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<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835S9Q9</accession>
    <name>A0A835S9Q9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015349</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000152">
        <property type="protein sequence ID" value="KAG2423322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835S9Q9"/>
    <dbReference type="OrthoDB" id="539810at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="97"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="154"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="185"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2423322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="198" mass="20492" checksum="18FC94067087CA36" modified="2021-09-29" version="1" fragment="single">MGCGASIQQPPGASPIYVEWSKASRDPAQDLPLSDWDREEVSGWFQRLVPGVQAYGAQLLPEEGYVVATWTLSYLVEKGVPAADARRIIAYRDRAMQQQQQQQQQSQQQSAARQPLRSSQSPSSSIATPAVGPPSATASPSRRGEEDAGDATVDGGGEGGGAGGRGGGAGAESGQQGGGASRPAVGERDPTAEGRSKT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SJ29</accession>
    <name>A0A835SJ29_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">UBX domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_014441</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000096">
        <property type="protein sequence ID" value="KAG2428092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SJ29"/>
    <dbReference type="OrthoDB" id="49605at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09212">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.2190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036339">
        <property type="entry name" value="PUB-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018997">
        <property type="entry name" value="PUB_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23153:SF38">
        <property type="entry name" value="UBX DOMAIN-CONTAINING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23153">
        <property type="entry name" value="UBX-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09409">
        <property type="entry name" value="PUB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143503">
        <property type="entry name" value="PUG domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="UBX" evidence="2">
        <location>
            <begin position="514"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="176"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="580"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="644"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="21"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="125"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="224"/>
        </location>
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        <location>
            <begin position="267"/>
            <end position="291"/>
        </location>
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        <location>
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            <end position="408"/>
        </location>
    </feature>
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            <end position="419"/>
        </location>
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        <location>
            <begin position="593"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2428092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="681" mass="65269" checksum="50A2B18E65CB9599" modified="2021-09-29" version="1" fragment="single">HIPSPPPAPGSGSGAAGAAPSGPPGRLPPPHAGAHDDVVLDARSGLALVNTPTAREAALVMARAGAAAGAAAGAGAAAGDGGLGGAGAAVGVVGGGGGGGGLLGAGVRGSPGTPTAHHLLLQAGGGGGSGSGTTGGQQFSAGGGGGGGSLLRDSDSPVALAAIAAARRSGAAAAAGARAGRGGGGGGGGGGGVVSTLSTPTAAERRLGGGFGPQPGQVPGGAAGGLDGGAGADYGLAPASAQAYEMQRCLGLILSCASPPPPGAPGAPGSSSSSAAAAAGSSPGSGSSSSSPAAECCELLLRLLRNVLTAPAEPKYRQVRLSNPRVQSALVGVPGAIEFLEAAGFKMEFAPDDGSETANQGFLVLPDAVPPTALAEPFRLLADAMAAHGLGQQGGPQGGPQGQQGQGQQGQQAAAAGRRQAQEEGQEEGGGVGRVPAAVPLAAAAAVERHTAVILPVAPDVEVPDWFFERTGLELKAAWQAAVRRREAEGTLMTRAMRERQQQQGGDAASSGAAAATTATVRVRFPEGVCLQGQFGAGEPVSRVFEWVAGCLRPVRQVQTGDGGGGGAVPPMFELITPDRKPLAITGPPPSAPSSSGAAAGRGRPASCSSQPPPRPNNVPLTLRSAGLLPSCLLLLRPVYLDGGPGGPGGGPGAGSSSSSRRLPLLRDELLTGAGGGVQLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SJ60</accession>
    <name>A0A835SJ60_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000096">
        <property type="protein sequence ID" value="KAG2428108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SJ60"/>
    <dbReference type="OrthoDB" id="526326at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052980">
        <property type="entry name" value="Crinkler_effector"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129:SF1">
        <property type="entry name" value="ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="605"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="767"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="605"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="623"/>
            <end position="646"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="777"/>
            <end position="788"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2428108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="880" mass="95275" checksum="E32A7848809D1376" modified="2021-09-29" version="1">MVTKAEAAAAVRAKTAPGKERARLLNWLDEQTDDQLHQWLIQAEDGHETIVECIKQKADPSAAGLGVGSAARAGSLPAAGGGGDGCSVEAARMMQALRKMSVLPGPGEVLKATSFHLHPDNDALFVRECYPRLFEALVCKPLPRLYIVTGTPGVGKSWFFYYMVARLLKSTRPPPFIVWEHLTVPNMAWCYKHKTGEVSFRKRSSFGGELNDDATWYISDGVPPQLNCRARTVLLTSPKRKTFKEMRKASARMLYMPLWKLDELLVCRRLLYKTVDEPLAEELYEHYGGVARSVLQLPKANPGEGLDTLLTDLHEAVAECDTAAMRQSVGSISRGPDVCHRLLHIVADEHFKKLYLVFASKWVAKEFAKKAVRDELQGLVSLLASTSGALKGMLYEATMHAVLSKGGRFTAAPISYDTGSLERGAEEDLVLAPCTEQEFFKALSDTATVETYYRPSSATFPTVDAFKRSQDTCDLFQMTVASSKTLDAKTLSNLVDELKLRQGVTPRLLFVVHEDSYPTFKLAAGKNWPPKPKQAASRVKLYVVKGVYDQPQTGTKRGAKTHLAGVALKRARTNPTPPPSPPTTQQERKLAGVAPDRVVRAVAGAGADSAQPATGDAAMKAAAAKDKDTQQAKEEKEEAKLKEKGKGKGTPAQAADCAATSGGVATPTTEPEYREAIVAMIRGQKGPVQLSVLGSVVKRPAAVGGKLKAYLESHPDLFAVTPAGVTLKSPPAKAAAQKTRNEGAAGAGLGQVAEGVRRRVIRWAQRQRRQTEGRASGLRRRRALRPRRVHAEPATNNTAQACAAAQQRFRLLCNAVAHSGDKRQTYCRRTARTRWFRAAPASAGAGAGDDEGEVAAGVGWQRAWGGGGGGDSWAAAARRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SJ63</accession>
    <name>A0A835SJ63_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_015337</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAEHOD010000150">
        <property type="protein sequence ID" value="KAG2423364.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056802">
        <property type="entry name" value="ATR-like_M-HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25030">
        <property type="entry name" value="M-HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="12">
        <location>
            <begin position="2263"/>
            <end position="2936"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="526"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="633"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1569"/>
            <end position="1631"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="526"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="572"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="592"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="652"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1569"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1599"/>
            <end position="1615"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1616"/>
            <end position="1626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2423364.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2947" mass="306769" checksum="8BF565FC568C8DB2" modified="2021-09-29" version="1">MNSQLLLDLQAALGAALSSGSQNSTPASQSNDPLVVKLRNGVGMLLDACAEASRNSTAAAGVEQDVVTVLSVAEFVVERLPMVFCRPDSLEVGPVRSLLGLLLAGASRFRSLVERMVSLLLRMLHLAPAGLRRALLLDLAEGAMELLMDAEQQLVVQALDQQALCCDTNPFSATTTATNINGDSSTVSLGMILTFEALLLRCGPTASSAAAAAAAAAAAGAGAGPGEGPVATAGCCVLEVQLDQYDRCMAASEAAAALLSSLVVYRSELVAPLVPHAVTQVLLQLIVAATQSPSTQTQLVLCTARIAAASEGTGFCEGLLQVALTLLEAWTTGVIALPEGGSPAPTSAGTGEEPQAAGTMAAASWHAAVSGAMQFCCAALEHRGTVALYADRLLQLCLRHCAAAASAAAPAAGGPPYSPTSPYSPYLVNLLAVLEDCPHLMPVAVRDGLMEVLLRLPPHPLQLATAGKPAVRAPTPHTQPAAAAEALRLRCAQWLAEPQVTAAIVDCVAVALGLPAGGVIPKTHVQSGVMSSSRDAQQVDSDTRVAPKPGRADMPGLERTLSADADQATLPIKDEGTERPTKRLRRTGAIGGKQQASQAAGGKYGNLQDMFASQAAIKQRALAEARTARDGGTQLAAPAAGAEAAGGGSSGDGRVAVGNARNPPAPGTARGPAGRALTAAATVVVQLMSAPATNPTPSPPPLPLSLARRQLLQSQLELLGRALAELLPLAGPELLLLAVRSLTELVRQACGAPGRAAGSASEAAAPVCDAAALTEPGLQAAVYRTTCVLVLAVLRALPELDVDLSNTAGVTAGVAAGTAGGSGTGGGGPRRGATVGADGAWAAAWGSGVQSLVDTALALVNPSPEAMCVDPESQSAEGAAATTAALVLLRTSLCTAGYSLAVSALPSACHPASRSEGLLVAWSGQCTALEKSLKRFFSATGVQGDAGLAIADSLGSKRADASQMSSAGDGRRFLTGVLGALGRNLVINLLPVGMLLPFMDFTDQSSTDRHVALSAIRMGGPDGIAATMLDEFARAVQCARSGQASIKVLEAPGLGAVAALVGGLQAAAELLAAKQVSQLARASLKAVVLGLRQLLVSLRQVARELALHSGGSGPELQPGARAAAAALLAAAASLPHLPEQLWLGLAADTLPHADSSGGGVDDEPCGSTQSAWPLLNRFAKLVEPWLGQAGGEGPGSISRAPAIAQVQVLTALRDVVHVCPASSAAKANATFAQAVFAALKSQHGIVRAAGTSLLRVCLRSGASADIFKAPAGSTANRAVREVLSRLHALMGDLRPDAGAVVRCSLLFSAVGLLADQGEGEAGLPGLTWRDCAPQLLLMVLGCLGAEDQQVRAAASCALGVLTAALDQSAQQLLLEGSHATMVLNTLGGSVLTSPRLLPELCRLLNATDAQLVRAIVPHAIGPLCCSNRLDELRELARRLDLPPAELFTLHAHHAYAYAFWKEPAAFDAFMERVEREVLERGHGDVVGRISMARMLTKQTIIMAGEPSDSWHVTGSLEPPAGLHERIEVFMRAIAAESREMETDDFVQELLLGEVAAGLFELFGKQLAQSPGSAGGAPAQAAGSKPEGRGGALLSPQRARQQHHHPHHHQSGHQHQHTVQQQQQQQQLVGSDVHHNHRTPTVESVDAEALQALRSLCVLVLMLGKHLPGHVPPVMVLLTAAVSRAIASSLELQLQSLAGWRVFLRCLAATAPSLLERVAVQASVVLLPLLQSPYGEVSSSAAGVLTLLVVDNKEHVRKALSRMPPLPAEVPGLEQVAAVLQEELQLADRRKRLAQLADSLQHDSLEVRHVALGELRFFLTDQRAFMCELVQRGCSGRTAVGAGMSPESSRAVAAGGAAQKQLGKRAAGATAAKGHSGAQGAVADAALLAQLLSALLRCCENTVRTRLGKDIRIRCGECLGLLGALDPARVAVERRAPPDLMDQDPSDAMALEAAAPAGSGAGATDKGSGVEARRVVAKSGGASAGGGGQYALEVALVENLVRVMETTGDLTVYRFTSYALQCLLQHYTGGSGDGSGGGPARITSGAAGAGGRAGAASPEPEGLYWEIRSDIRPLVKPYLTTRYTLEDVGRGGRPEVDSWLAGNPLFNAPKRPSYRRWMTLWIRAMLRFAVGPHQAAFNAMMPVMRQDLPLMSFMLPQVVHAVLVSGNATATEAVRREVVAVLQAGAAGPSEADGQLELYLQALFGLLDVLGRWVKDAWQAVGATGSTQAAAQAPGGGGGDSSVSELPARAQHVRAFIESIPMETLARAASRCGAHARAVQTFETHMRSEAIKAHAATQSRSATSGGLNPAADISRPQYKALNADVSFLLEAYGQLGEPDGLAGLCAMRPSGLSEADQVLVAERAGQWGDAMALYESAMRRDGDGGRDAADALSSEELLSAAGAALGAPGRSSCFGAAALRQGNQPVLGADSDDSAGSGALCSSQAGYVRCLLAMGHSQAVLSSVDGLLARGTCTPSAAKQFAALGVAASWRLGRWSRLRGYLHAVEVAGPEFGEHGEQQQLMPGCTPTATGLSPSDQWELDIGHLLDTLQRGDWARVRDLLEGYREESMAVLPALAQESYVRAYPHMVRLHMMQELSDVLSLLDPSCGWTGLSANERARRLRWPDRMASTQALLPTQEPLLSFRRQLSALMGDREAEALAVAGHRETMPRERAVLEAASRGVGAAAALESAKLLRARDLHHRAASELQSAIHELSAAHAAMSPAAADPKRMLARLKLCLARWSAGQGGRAPAELRRLFDDALNADNAWDKPHFHYARYLDQIYQDARRRQTGAWEASPFGGRVKVVIGDERQYYEYLPDVLRHYGEAITKGQKHVMQALPRMLTLYCEHGSDQLARGTNAPRTGRESRAATDVLNTMKLLAATNIAPPKWLVALPQLISRIAHANKEVSEVIRIVLVRLGEAFPPPGAVVSCGRDAAAQFAKRREGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SJU1</accession>
    <name>A0A835SJU1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Peptidylprolyl isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_014724</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000104">
        <property type="protein sequence ID" value="KAG2426871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SJU1"/>
    <dbReference type="OrthoDB" id="72596at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039663">
        <property type="entry name" value="AIP/AIPL1/TTC9"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242">
        <property type="entry name" value="ARYL HYDROCARBON RECEPTOR INTERACTING PROTEIN RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11242:SF0">
        <property type="entry name" value="TPR_REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0802">TPR repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="259"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2426871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="381" mass="41263" checksum="C513E78BD24A0253" modified="2021-09-29" version="1">MPLGGAFQELIRAAAQLKTTLIKQRPGRQEWENSPPFMRCTAAPTDTVSRAREGGFSIQNSTALQLKEQGNDLINKDPEAALGLYTQAISVFLWFDRGPDRAAEDIPLVCAADKLPESEREQAHHVLAVNFCNAAACLLSLNMAADAAYACTQALRYDPYSVKALYRRALAHRSADTTAGLEAALADLAAANQLEPANNQVRLALHALQHELRELRRKERGLYGNMFQKGGLYDSETATEQVAAAAAAVAAAAAAVDSGTSHGEGWRGGSNEGERPSTSGRDPEDLTFEYLQAPGNRKRSLAAARNRKMAERLDAARAPNAGRFPWWAVPWWAYALIALHLIYRVIKIWRIPVPAPTGGAGAALPKLPQQEVLATPAHGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SL66</accession>
    <name>A0A835SL66_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="27">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="27" type="ORF">HYH02_014682</name>
    </gene>
    <organism evidence="27 28">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="27" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="27">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Flagellum axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the dynein heavy chain family.</text>
    </comment>
    <comment type="caution">
        <text evidence="27">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000103">
        <property type="protein sequence ID" value="KAG2427037.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5593012at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030286">
        <property type="term" value="C:dynein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045505">
        <property type="term" value="F:dynein intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051959">
        <property type="term" value="F:dynein light intermediate chain binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008569">
        <property type="term" value="F:minus-end-directed microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060271">
        <property type="term" value="P:cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.1220:FF:000001">
        <property type="entry name" value="Dynein axonemal heavy chain 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.710:FF:000004">
        <property type="entry name" value="Dynein axonemal heavy chain 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:002141">
        <property type="entry name" value="Dynein heavy chain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.140.100:FF:000001">
        <property type="entry name" value="dynein heavy chain 17, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000044">
        <property type="entry name" value="Dynein heavy chain 5, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001328">
        <property type="entry name" value="Dynein heavy chain 6, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1270.280:FF:000001">
        <property type="entry name" value="dynein heavy chain 7, axonemal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.920.30:FF:000009">
        <property type="entry name" value="Dynein heavy chain 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.1120:FF:000005">
        <property type="entry name" value="Dynein, axonemal, heavy chain 12"/>
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        <source>
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    </evidence>
    <sequence length="4779" mass="518941" checksum="A10D1E39970206FB" modified="2021-09-29" version="1">[encoded data, 4779 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SL76</accession>
    <name>A0A835SL76_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_015532</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000358">
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        <property type="molecule type" value="Genomic_DNA"/>
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    </dbReference>
    <dbReference type="GO" id="GO:0004672">
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    </dbReference>
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    </dbReference>
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    <proteinExistence type="predicted"/>
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        <source>
            <dbReference type="EMBL" id="KAG2422031.1"/>
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        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1444" mass="152431" checksum="1EF88C8C55A725CF" modified="2021-09-29" version="1">MAPKQKGDAKVSTAASFDVPLPPAADLDKSLIDGDNAEIIVTVLAIVASDGARLHEVIKRYAPKHSFEGGQGKIWKVQLQPRLDPASQLVLPVIDMRAGPDKKMAKEGLSEEQLKTKLLGTPVPGMLKLIWTRYEQTGQILDLARNIIVQAVLSTGALGFLVQRLIRVSVTPVLKKHVAAQLRLQGGVAAGGGKGTDKVQAAADSIEGLLATQLAPQQDGSMADGLRSIAREYLRQVKLESHADMLARAVTYKTLPPVHENLVEDWMRIGTVLLMILDAMDQANVVHRDLKPANFLMSIMDGGTWMATRLADLGLARMVVDSQLNLTPGLLGTPGWMHILRCLWKAVFGEDPIRISDKEMDRQCGGKVLLSMPLSGELLQRHPISLGVGAFRYMLSWFSTEYLLPCDDRVGYGNAPVQLLGIQFALDLYLVGGTSQELSEALLLLTLSQTVSEQPQGRAVFATRAASTGEYLQRSEALFEECRPAWEAHAAKRRSMPTDAILDGRVYNAKQRLSEATALVREILGLCAVPQEEMRDRRVQAAVEQLMQRQRSAATLTCVGSGDGLQLKVAWVNVEAELRCIRGTFGGAGGDGTAAASSSSSSSSSTAAVNSGVDLTGTASGLNTATGGGRAGVGGAADTGLDTLAALSAVQLGLQLFMSMTEWHLLVVQRPNMVAPGRDAEEHEAHEEREEDEEDELWLRKVKQASTDWAQAAAQQRDVRNQKDLSSAMTVAAELVASAWCHQLAVDRGDALSPLHHILAGSDAAVAEAAARKAAGADAGSGGSGGLGSQVQRAGGISAAAAGGSTTAGGGVVAATVSAAGSAAGSAPAKGVIGVLPLHVPANIAFSRTIEAALALGPKSIQLDMLRLLFATDGRGNLLFAGPTKAMSLDIANSLPTAERAHVLVEMGFMSKQQAECVMNIRELPRHVNRGKEVRVAYTLQQTFAQTWPRVEQQRAREEKRMQKDMQQLDQDNKVQHRHDLNSRQKGWMTQQQCDAAAKKREEALEEKKRQLRERLTAFDTTQLQQLREVMDACMLTNVGQSLDKEAQKKLCFSLTCLMPALVSYANHALTQSMSIAAFLQQHPRALAVSLRGQQQAAAVRPAVAAGAGAAAAAAARPAGPAAAPPPLAPPPLAPAGRRGRGALAPVALVPRKAPGEIAAGGRPGGVVPLAMAPAPCQGAAPTAMPAAVRGLGGAAPTAMAAAPGAPLLSAGPDEAGMEEAGPEEAGAVDAGSEAEEAADAMAANVVMLVNRSAARTWAQYSAYQPRCSASAGSCASASAITSSRDASTSSSASGACSSGARAEQLVHAAIQTCDSEQALKLLIHKLAAFNTQDLREIEDPASPLVPTLLQAAQAAQVQQACGHAVMERAPPQPGQQGLAGLQGGPTSEPPMPQLAATMERKRQCPQEDVEMEEAVQPLQVLEEMLEDEQQPGEQPRKRQRLAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SLZ6</accession>
    <name>A0A835SLZ6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">TIP41-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_014041</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TIP41 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000085">
        <property type="protein sequence ID" value="KAG2429459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SLZ6"/>
    <dbReference type="OrthoDB" id="10253878at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031929">
        <property type="term" value="P:TOR signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051330">
        <property type="entry name" value="Phosphatase_reg/MetRdx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007303">
        <property type="entry name" value="TIP41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021">
        <property type="entry name" value="GAF/PUTATIVE CYTOSKELETAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21021:SF16">
        <property type="entry name" value="TIP41-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04176">
        <property type="entry name" value="TIP41"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="102"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="171"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="106"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="171"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2429459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="325" mass="34788" checksum="2DDC9657517B5495" modified="2021-09-29" version="1">MGDKEGDAYRRLLSAIVLPEMVFHLNRVELVHEASGVVISLNAFDALAGWRHEDLPPLQVRVAEEWRRAREHEIAQQNAVQLTYDWTFTTPYTCTVVPPPQPPPAAAAAVSASAGGDTAASDSAAGEGPGAAAAAAGAEEASQQQLPGELSLRHHPRGVADFVCDAPGSTAATAATHHGSSSSGPGAGAASTAAADGVAAAGHHQPTGHHDPHPHQPQPQPQPQTCVWRPTGDQIDRGLLMERDPILFYDEVPLYESDLDDNGVCAVTAKLRVMPRCWLVLLRCWVRVDGSMVRLRESRLFCRHDMRSKALEVLQVGRRACVSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SPB7</accession>
    <name>A0A835SPB7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_013572</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the MT-A70-like family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000077">
        <property type="protein sequence ID" value="KAG2430733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="14833at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036396">
        <property type="term" value="C:RNA N6-methyladenosine methyltransferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045123">
        <property type="entry name" value="METTL14-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007757">
        <property type="entry name" value="MT-A70-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13107">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13107:SF0">
        <property type="entry name" value="N6-ADENOSINE-METHYLTRANSFERASE NON-CATALYTIC SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05063">
        <property type="entry name" value="MT-A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51143">
        <property type="entry name" value="MT_A70"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51592">
        <property type="entry name" value="SAM_MTA70L_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="152"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="385"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="578"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="664"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="898"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1064"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1387"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="10"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="48"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="95"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="165"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="180"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="220"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="292"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1064"/>
            <end position="1096"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00489"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2430733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1427" mass="145353" checksum="DAA0E88CB53066DE" modified="2021-09-29" version="1">MGGVSSSGGQQQQQQQQQQQQQQQQQLISQTDLMLLEAELDAAEQQHEAASAQQQQQQQQQQQQQQQQQQPLLLLPPKPGPLGMGPPLPPPPPLLQASVQQQQLHRRISGSSSRAARLGYLGVAADEMLERLGPAVAVAAATGTAAAGGAAGYAGSGSSPCSKSGELGPLGYLGLPQRLGSGGSAGGGVGGDDDEGSPPPLDLTWLDSPAATTATGGGSRRPSAAGAAAAGAPTDQQQRQQQQQGVLQLEEPAEVVSARLAPKRLRLVPLTPQEVQELSARGMLPSEASPPRKLPPPPPLRPPPPPLRPPPPPPAAPKRLRLVPLTPQEVQELSARGMLPSGGGAPVPLAPPPPPPPHDEMLLLRAAPATAGGGGAYAMELAMTTHQQQNQPPPQQHGSVGHRRRRLAGDDADEAFYRYHDSDEAAASAAAAAAGVAGAAVRLVRPRRSDAAATYPLAAAGAGATAVGAGGEAWADDEDEDVQIAERPPPMLISAAAGGLVAAGLGSPPAGAAAVAAGAASRDDPRRMLLLPLSHQREQQQPPQGQQQHLTAAVTSARTTAAGAAAAAAVHATAATAADRADDDVAGGGGDDAGDGSQQQQLALRIVDVDLALMPAVITLIRTAGMLGGAPPVILIQPSQAVPPPPAVTAAAAAAAAAAATGGAASAAPDGSSGGGGGLSRPLAPPLLIPAPPPPGVVRTLYQQPDGRILVGRETPMTPAAAAAAVSVAPGPAAAGATTTTTSTTGTARRRIGGILGASAELGMRAQTRPELEEACLGSLREIVAAAQPITLSAAAGAAAAHEAAPPLPPSSGAAAEEAAVQVMHVPASLVLGAAARPAAAAVLARAAVAAAQEGPLHGRRHADYYDDQQLQPQQQQQQQQQQQQQLLLPLQAAALQRDGGRGPRPIHGDMGPPQLPMGMFPPPDPSAMMGGAMPGMPPMDFTPEMLLSMMGAGPMGLGGPMGLGGPMMMPPDFGGAAAQGGMMGGPGGMMPPPPQPPGGGPGGMGMGGPMGGPMGGPMGGMMGQQPGGMGAPMGPPMGGGMGMGMGGIGGGGGAAGGGGYGGRGGPGEGGRQGGGAGGGGGGAGGAGGGGPGGGAEHISNDYSQNFVDTGLRPQNFLRDTHLTDRYEEYPKLKELIVRKDRQVATHATPPLFLRADLRSTRLTPELFGTKFDVILVDPPWEEYVRRAPGMVADAEVWSWQDIQALELEAIADNPCFLFLWCGAEEGLEAGRVCMQKWGFRRVEDICWIKTNKEGGKGPGGGRRPYLTAANQHPESMLVHTKEHCLMGIKGSVRRATDGHIIHTNVDTDVIVSEEPELGSCRKPEELYHIIERFCNGRRRLELFGEDHNIRNGWVTVGKSLTSSNFSAKAYADHFRNRDGSVWVQNTYGPKPPPGSVILVPSTDEIEELRPKSPTGPHGGSSFHHSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SQC1</accession>
    <name>A0A835SQC1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000073">
        <property type="protein sequence ID" value="KAG2431377.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SQC1"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="29"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="84"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2431377.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="144" mass="15328" checksum="1422F6BAA9A60A64" modified="2021-09-29" version="1">MIFPKLLEDSSNTVASESEDGEADVLGKVAYLTLATACSMFLVCLGSAIMLFDMVTNVLNTDADFQWLAGSRLMVFMIDVPQNSLSFGCALAAAGVTLVAFAQQPLPWAGAFAGTFLGPLIGCTYLLVRLGQATFKQAARNYVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SQC4</accession>
    <name>A0A835SQC4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Acyltransferase</fullName>
            <ecNumber evidence="14">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_013405</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="2">Glycerolipid metabolism; triacylglycerol biosynthesis.</text>
    </comment>
    <comment type="pathway">
        <text evidence="3">Lipid metabolism.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 14">Endoplasmic reticulum membrane</location>
            <topology evidence="1 14">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the diacylglycerol acyltransferase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="14"/>
    <dbReference type="EMBL" id="JAEHOD010000074">
        <property type="protein sequence ID" value="KAG2431273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SQC4"/>
    <dbReference type="OrthoDB" id="264532at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004144">
        <property type="term" value="F:diacylglycerol O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006071">
        <property type="term" value="P:glycerol metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019432">
        <property type="term" value="P:triglyceride biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07987">
        <property type="entry name" value="LPLAT_MGAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007130">
        <property type="entry name" value="DAGAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317:SF0">
        <property type="entry name" value="ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12317">
        <property type="entry name" value="DIACYLGLYCEROL O-ACYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03982">
        <property type="entry name" value="DAGAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="9 14" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="8" id="KW-0319">Glycerol metabolism</keyword>
    <keyword evidence="5" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="11" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 14" id="KW-0808">Transferase</keyword>
    <keyword evidence="7 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="6"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004477"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00005420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU367023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG2431273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="302" mass="32577" checksum="126B4192749EE754" modified="2021-09-29" version="1">MVATLLYVQSSALTVAFLLYLAYVVVGPGSKADASCSWKPTFRKWRIWKVMVAYFPGARLVKTADLDPTGRYLFVSHPHGIIAISNWLAFGTDALGFSKLFPGLDLRCSTLTSNFWMPGVREYILAHGMCGVGRDTLKSILSSKPGRSVMLVVGGASEALLAAEGTYDLVLRNRKGFARLALQTGASLVPVINYGETDTFHTYIPPPSSRAAAIMKVLKQVFGFSTPLCWGTGLFGGWGMIALQVPLTVVVGAPIKVDKVAGASEAQVAALHKTYTEALLKLWADTSDKYGKGVKRPLTIVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SVK8</accession>
    <name>A0A835SVK8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_012479</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000059">
        <property type="protein sequence ID" value="KAG2434019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SVK8"/>
    <dbReference type="OrthoDB" id="537063at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051589">
        <property type="entry name" value="Sialate-O-sulfotransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45964:SF5">
        <property type="entry name" value="WSCD FAMILY MEMBER CG9164"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00321">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="8"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="domain" description="WSC" evidence="3">
        <location>
            <begin position="167"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="475"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="508"/>
            <end position="522"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2434019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="593" mass="61278" checksum="E507D04C6E8DF262" modified="2021-09-29" version="1">MCPSLFVVQKQIGCFGDHLERALDGYYFGYQTDMTVEVCASKARSQGFPYFGVQAGGHCLAGNNLTRALTLYGPASACTSKCTGNNNQYCGGSFQQNVYFTYPEDVCRGNPCDDGGLQGSTCTAVPGGSGLNAYSCSCPANSARNSSQASCTCNSGYSLSGGACGLVQKQIGCFGDHLERALDGYYFGYQTDMTVEVCASKARSQGFPYFGVQAGGHCLAGNNLTRALTLYGPASACTSKCTGNNNQYCGGSFQQNVYFTYPEDVCRGNPCDDGGLQGSTCTAVPGGSGLNAYNCSCPANSARNSSQASCTCNSGYSLSGGACGPCPWPGDPSLGGSYAFSCSSCTVSSSTATAPCTLSCNCRDVSGYTHYSSLPLAACASKLVDNNNGQLTCRAEPQPSLSPPPTPLLAPRPLPSPPPPPSSMRRCDKPSWWCGDTNQVAKQVFCDDDGTLDWICVEPSTGKRGAITSKLSCASDDSRTGWPNAPSSLCPSEFGTASPPPLPPPVSSPSSLTRSPPQSTSSCPWAGDPSSVGGSYAFSCSSCTVSSSTATAPCTLACYCRDGSGYTRSSSLPLAGCASKLVDNNNGQLTCRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SWM8</accession>
    <name>A0A835SWM8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000056">
        <property type="protein sequence ID" value="KAG2434574.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552990at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="240"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="299"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="500"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="873"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1096"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1273"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1637"/>
            <end position="1667"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1706"/>
            <end position="1738"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1762"/>
            <end position="1836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1924"/>
            <end position="1959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2029"/>
            <end position="2140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2445"/>
            <end position="2467"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2722"/>
            <end position="2748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="514"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="892"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="916"/>
            <end position="932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="941"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1096"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1273"/>
            <end position="1287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1637"/>
            <end position="1647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1924"/>
            <end position="1957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2029"/>
            <end position="2052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="2053"/>
            <end position="2065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2066"/>
            <end position="2094"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2114"/>
            <end position="2127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2434574.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2807" mass="270481" checksum="F18EE634E461B452" modified="2021-09-29" version="1">MLQLLAAVLVSLVALVASGVFLLRGRIWAHVCKAAGLEVCTAERLSLAGGCRRLRLELRKGPVRVVTLEAASVLRWREDVEPGAMGSAAVLLMLLRLLAAALLGGAWARGPKSGAALALVTLQGLEVQLQPPGGKAPTAKPRSGSAKGGGKHGGGAKPPPSLPAPLLRVLPLLKLKLQDIRIITAAATSAGAPPSATAAAGAQPPAGRQQSSQPAAPGTTGASSVEVFVAAVELGAARPDLAQPGLSSSGAGPGPGGPLRQRSLLSPQTSLLLHRQFSAEAPDAAAAAAAALGGATVGSTGGGRGADGSEAGAEGGGGRSLSVTSGGRPLTVSLQVSGIEAAVRQQGRGQEEGRQGRQPALLSASCPAVMVTSSFGIGTRPWSTTARRSQLLSAHVELRQVELSCDLEAAEGLGLGVAGRQPAAAVAADADAEAAAGEGESGNGAAAATAAAAPGAGQGADGAELSLAAALAALASLGISKKARRAAAAAAGADAALPAGSLPRAVPRLPQSRGSSPSKASAPAPEPAGGGVESASAVLKEQVAAALSRIGFGLPEEVSLRLEGVVALVWLRAGELRVPTASGDVAASGAARGTSPGAAHAAACAQVALGPSEVVVCGAAHPAAEGPAAAASAAAASGAPGAAELSLLAVAVELGPAALVAGPAALFSGPAADQVAARALEVAPLHLGLPRLGLSAAVSVPALLLPSSTSSSSSSGRFLPRRSSGSAPLARYRLSAALDLPGAVVNLRPGAAAAAAAAAAAADVTGSTAAAAHTAPGRLAYSSALRGVSASAELAFSGVQPVPPLQGRAAAALESASPAVVASTPPSKSATGLSGASTAGAVVGEGAAANVGVQAGAGAAAAAAAAAGLEHQGTSGLQRQTQIHRRQQSAGVGVGAPGGGPGGSAAPTTPPKLGRAASEPLAAAATATAAPGGAQGEDTTADAAAAPAAPAATSLHEAESAPAFAAATSEAVAALEGGGASGQVGRDQQQQVQQQLGAAAASGAISGSVLLPGDGALLPGEEAGAQPVAAGTGAVAPSLRPSESSAVPESPAPAAAAGAGADPATGGDPQSAAASADAPPALTFELTLESLELRASATAATTPETSSPPSRTSTPSAAAAGGGGKDKAGPAAAAAPPALLLLQRTVFSATGALAAAGGTGAAGPVGAGAAGGAPSALLGLDAAVRLGRLELELQPAQLQPLAAAAAYAAGVAAAAASAAKLSAAAAAAAAAAAAAASSQQGSHAGSAAGAAAEALLKSAAAAFASQPSAAARAGADAAPEGGPAPGSKSRRRRMVAVRLNALGLESAHGMRLVLHTAVALDPLYRRQPAAAGAPEVPDSKGGLPPAAAPAAATAAGKVLELVLTSMRLNLWGPAAAAAAAAEAGGAAAAAATSSSSSSPQAAVVTTELSVHNISAVVIHGARLAPSGGGSSSSSSSEWAAAGPERQQLLRLDRLKLLGCRPVVAGGGSGGGAARAAVGDAAGMAPLPAPLQRIDLRGARLHADVDVALLGLALTSGWLGLAAAAAAERSRGRRAVACVHVAAAATAAGEWEPGVAPLGKGSGKVAAPKAASRRRQVLELRAADAEANICVGASDVVTVTVREVRASSVLGAVTVEAAAARVNGRRLLDVEFLSAGAAAPGTTPGRPHTGPHGHHTPTPSDSDVDPSIFRTSDVAADTVPGGGGGRRHHRKTSSVLDILPGAGAAVQSVQSVQSEQHPVAARGVSQPQPPAAPRGKGILRPRPHAAALQPWVALGAPPAWASVTARPADTSSGAAAGEAKRPPAGGDAKSPLARGASEARRQAARARFQLPPQPAAPGPSAASGPPPPAAPAAGEGGAAAGGAAAVAVGVRSVALALYGATLTVAHDESAARVYVVGELWSRAVKQVVGPRVAALKSALQRLKQSTSKGSAKDSYSYKGAHAAEGTGAATDSTGATGPAAAQSQAQVPPPATATATAAKSKPHVEVVLDVRRLAVVVEHQPLEGWLAAHGAALQATATQRHLYERLVSSYAGSWAVKAARRDVAAAAAAAGLDSSSLTSLSSLSPGLEPSAAPAHRHHRHHRKRRPSSSSSSSSTSSSSSSSSSSSSSSSSSSSSSEDEVPKGGRGKGAPGSKGAGAQARAADAGATGKAHHHHHHRSEEWERAMRDVCASYVAVCRALESAAAITSVAGGGGGGATAGAGAGAGAGAGAGAGAGTAHGAAGKAAAGLGPGPAAGSAAAAPAGAVAGSGQPTGVAAAAAALGGNGGRGSCFKSCPGGALLHLVAAEAQVCLVVAPAGCTAGRKVAEGVIARLDSPAVVGVTFERVVAVSLDAGVADLQVTLAGCGSPLAPSPLLRAQQVALAGWIIRARQLAAPPRTAQVPAVWPVGREHAAPVAVPLRFTRPNMKTYTDLRVEADGVNAAFSTALEPALAQLTKALKARVIPPAPNLLLPSGRVGPPAAAAAQAGAATAPGGGGGGGVDSAAAASSPSGLPPWDNIRYVWRGGLKVMVRNLVALVALPPPGAAPAAAADLPLNPRTDPRLGLSAATLGVSVGGGGRCDVTATSLAVVGHVQGPGRGPGDEQVEVPLLALPLLTTSLHAAFKQPAATPYAFPLLRGPAAPQGAIQEPVDVPGLMRATSWSLGLDIALARDAAAHMQQQQQQQLQHSGAAGGASAGAAAAAAAPLVEHLAFTLPELQAATAGCSGPEALPRIFIGELQVRLLMDLVRGLAGGAPVATRGAWKRRTCYEPPRPPRGAGSSGSSSGGGGGGGGGLGALLGRTDISLAADVVDIAHDAQDPADPADMVYLRLHSLRYSNSFSYTKVGGGAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2023-02-22" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SX06</accession>
    <name>A0A835SX06_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_014466</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000097">
        <property type="protein sequence ID" value="KAG2428075.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SX06"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2428075.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="171" mass="17523" checksum="A42C26C44B5A9F42" modified="2021-09-29" version="1">MPSQTTAALAETNCSTNVNCTGFIVADDGRGWYLSAGRILQYSRSIGMCTYIKSGMSWGNAACTCQDTYPANNPATGEVLTYSGCTGVAIGTYIPDRPCPTPPSPAPPGPRFANCAAKPGFTALADTDFGSTSVGFGATAGLYQTTAALAENNCSTNVNCTGFIVADDGRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SXN9</accession>
    <name>A0A835SXN9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012065</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000054">
        <property type="protein sequence ID" value="KAG2435069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SXN9"/>
    <dbReference type="OrthoDB" id="552587at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="581"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="663"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="533"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="581"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="683"/>
            <end position="694"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2435069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="859" mass="83400" checksum="DD3B03F1DFBFAA64" modified="2021-09-29" version="1">MGTRLEELELQLCGGAVVPCEGLLALAAAARGATATRAASAAGGSVRSDATAERTREPAAPASAAAVEPPCWILGRSPRIQKELPDRALLEQRGEAAVAAAVETGPPPVAVAVVGGTPVRRAGGATGGRGLRELRVILALDKHMHIGPFRYGTQARPGGAVGRCTGAEAWRRNGGGATAAAVGAWVLPLAQAATGRAVPPAVAAIASLAPTLRSLELAGPCVERVLDPPGRLLGLSALTALQRLRVELPAATEPYGSGAAGGAGVGYGVGGGGRFGGGGGGGGGASAWDGGGGGGGVSDGGATCDGAGGWKLGPLLAAMPWIRDLDLGPSYRLPPEALVSLAALSQLSRLRCGSIATPPPQQYRSLAAAAAAATAAATVAALAASEAPEALLCRQSSSAAGAGAGSITISGRGMAADETLSASHEVPPVIEGAEAGLGAVLLPLPAGVLQLPLPVALEVLEVCTLPAVPVLAALAALPRLSDLRVTPAAPSAPASAVAAAPAACGSVRQSTLPTTTATATAAVAACTRLNCSSSSSSSSSSSGADGSSSLPRATARPGAVPGAAGSGGGRVWVLAHRVQSTAPGGQAQTSFPPSTSGGGGSGGSGGAYGGGADAAAATAVAPVASGAATAQIPAAAAPADAAASSAAASCEPLRLALVGDEWEHGQHHPGGGMQLQRERAGRRLAAAGAAEQGPPGAGGAGWSQPQEVVTAARLLRRVLPPASRRRLSLHPFTRSPARLAGPHAAWMSELWPLAGDGDRGGGGSRGGGGGGGGVEAVEVAGLDLAAGDLEALLAALPGLSSLGLFMCRLPDGELARRLQAERPGLAVRVDSSCVFDHPPAAASALPGSHMPYGRGGYGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SZU3</accession>
    <name>A0A835SZU3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000057">
        <property type="protein sequence ID" value="KAG2434492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SZU3"/>
    <dbReference type="OrthoDB" id="543907at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2434492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="218" mass="23712" checksum="3727101500E5A84A" modified="2021-09-29" version="1">MSTGAAATTAPLPNGDDNDGRYTLGHYYGSTKKVKVPELDHNARRRQRVIAEIVEAGRRLGIKEDVIRTNLDKMEALLPELTPDVNKMRAAEWAKLARDVNQVAMMLVVIKTSYPGANVGKIVSRAPKTLLQSPEQLQADAAVVRKVLAGAPNADAIIEEVPYLMSPPALAQSLSNVSRWYNTKDPVAMISKNPKLLLNVEEADLEADPLYGELTTAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T2D4</accession>
    <name>A0A835T2D4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_011070</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000045">
        <property type="protein sequence ID" value="KAG2437692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T2D4"/>
    <dbReference type="OrthoDB" id="543893at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="292"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="806"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="217"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="320"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="533"/>
            <end position="598"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="812"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="217"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="320"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="555"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="820"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2437692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1127" mass="112047" checksum="679B0D9A4D014D78" modified="2021-09-29" version="1">MSRTADAFCCAPAGCPALPALQVRLAPGVTLGLRRILVRRSRSDPSWRGPGLDLITDDSGRDLTGADPAAFAVVEVADSVNLQEVCLPPAYVPLSMGTMTWPAELQLPPFRQSGFSFNTTQQLHPNCTDRGGGTTSNTDLPYEQQCILSGGIYNAIGLYCYSIDAFGNQVKTGYVSLIRNSEFQCYTKMTVECISSHGGVVGCYNYMSKQMMNNSFTTTSSSSNNNATAVTNTTTTTSGSNRSSSTAAAVAAAPAGSANTPPLPPGAIGSSAGTGGDGGAGSGDSAAVTAGAVVGSVVGGLLLAAVIVVLVVLVRRRRQSAKHAKQQRRQHSPETGPASCGDRCGAGAPAACAGAAAAAARGKTDGGGKAGGGGGDGGAAAFLLDSPATAAAGDSSGGDSGSHPCSGDGFASATGTAAGTAAGGYVSGLTLASAAAAPSPAAVAGAGGGSAGGGSGSASDGGAAAAAAAVAAAAQARAAAAAAAAYSMVPVTALTPLNANIPLNIMMTTTNTNTNTNTNTTLTVSSAGAPALGSSTAAAGSEHVVSGHRKPPAPGAAELVAGAAGKSGSSSSVTTTPPPATPEPSGGHGPTSPQPPPLVMLFPGQVIGKGSYGKVVEGLYGGRRVAVKLIDTGLLLPGAFTAGAAAAAAAAATRGALPPPPPPPPAWAYTSLSVSTADVPPPLSAEAAAAAAAAAAAVEPPSGTGAVVGTAMAAAGAATSSQQAAVVANAADAEEAQRAEQARRQAAEANQSTAAAAALAAVAAAAAVEVPDMLAVSGVVSSDDGRLLLGTDTQRYCEAVLQLGHYCGAHEAGGGGGGLQQQQHQHQQLSPPPPPPQVQKQDAHVAHGGGAATLISSGAAGAAAAAEAAAAEEEEEDAAVRDLISSLGQEVEVLARVRHDNIVTLLAANLRPPHVCLVMERMDTSLDRLLHKEPGRRLQLDTALHIALQVARALQYLHPTIIHRDLKPANVLISHADGDGSQLVAKLADFGLSRLRNTVLVTCNPEVGTGPYMAPECFDLATNVIMDRADCYSFGVLLWELVTRRRPWEGLSMVAVAVRVAVRGERLPLAPLEAAGAPAKLVRLVASCFEADPRRRPAAAEVVKTLLLVQEQMKLGTEAGLGKMLGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T4G7</accession>
    <name>A0A835T4G7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">2'-5'-oligoadenylate synthetase 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_013022</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000068">
        <property type="protein sequence ID" value="KAG2432300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T4G7"/>
    <dbReference type="OrthoDB" id="549996at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001730">
        <property type="term" value="F:2'-5'-oligoadenylate synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.20">
        <property type="entry name" value="2'-5'-oligoadenylate synthetase 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11258">
        <property type="entry name" value="2-5 OLIGOADENYLATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11258:SF11">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50152">
        <property type="entry name" value="25A_SYNTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2432300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="367" mass="40399" checksum="C49915627519CE9F" modified="2021-09-29" version="1">MEVILASDDDLRRMYLNLRPGEEKSYVSYFNGNVLPLTVRGVLDAIPQAATDKMDRVHVGGSFGRRTLVRGAFDVDLTVFVNSYNGQVMRFDQWTEQTLINMQRDVAAWLRTKGWNVVEVEYGAHYKNCLSVTVLVNGRVEVEVDIKLAANVVQGSQEPNRGKAQRDALMAALWDTPAAQRRADPAREAALAEALTAVVKDTSDRVKSVARLLKSWYKYGLKRDIPHVPSVLLEVVTLAAAGQVNMDAREAGVLLLLKALELLDAAASGREVVVLEAGPKWGYTRAQANSCAHVWQWDAVKVLHPIDPTCNLARPKTGGRVIYWSSLAQEARDLRDVIKTRSMWDLLYGSSSSLAPAIQAMGAAAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T5H8</accession>
    <name>A0A835T5H8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ubiquitin receptor RAD23</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="5">DNA repair protein RAD23</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_013178</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="5">Multiubiquitin chain receptor involved in modulation of proteasomal degradation. Involved in nucleotide excision repair.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Nucleus</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="5">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="5">Belongs to the RAD23 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000070">
        <property type="protein sequence ID" value="KAG2431961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T5H8"/>
    <dbReference type="OrthoDB" id="419317at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003684">
        <property type="term" value="F:damaged DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031593">
        <property type="term" value="F:polyubiquitin modification-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070628">
        <property type="term" value="F:proteasome binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006289">
        <property type="term" value="P:nucleotide-excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043161">
        <property type="term" value="P:proteasome-mediated ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd14280">
        <property type="entry name" value="UBA1_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd14281">
        <property type="entry name" value="UBA2_Rad23_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01805">
        <property type="entry name" value="Ubl_Rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000002">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000003">
        <property type="entry name" value="UV excision repair protein RAD23 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.540">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004806">
        <property type="entry name" value="Rad23"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006636">
        <property type="entry name" value="STI1_HS-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015940">
        <property type="entry name" value="UBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000626">
        <property type="entry name" value="Ubiquitin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015360">
        <property type="entry name" value="XPC-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036353">
        <property type="entry name" value="XPC-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00601">
        <property type="entry name" value="rad23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10621:SF0">
        <property type="entry name" value="UV EXCISION REPAIR PROTEIN RAD23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00627">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00240">
        <property type="entry name" value="ubiquitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09280">
        <property type="entry name" value="XPC-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01839">
        <property type="entry name" value="RAD23PROTEIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00727">
        <property type="entry name" value="STI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00165">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00213">
        <property type="entry name" value="UBQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101238">
        <property type="entry name" value="XPC-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50030">
        <property type="entry name" value="UBA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50053">
        <property type="entry name" value="UBIQUITIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="2 5" id="KW-0227">DNA damage</keyword>
    <keyword evidence="3 5" id="KW-0234">DNA repair</keyword>
    <keyword evidence="4 5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Ubiquitin-like" evidence="8">
        <location>
            <begin position="1"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="152"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="domain" description="UBA" evidence="7">
        <location>
            <begin position="350"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="199"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="204"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="249"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023204"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU367049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50030"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2431961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="393" mass="38865" checksum="69189DAE31AE56BE" modified="2021-09-29" version="1">MKLTFRTIAGKSFNVEAEESMTVSALKDKVQESQPDCTREAMKLVYKGKVLDDATTIGDNQVTEQGFIVVFIQPKAKEAPKPADAPAPAAEPAAAAAPAPAAAPAAAPAAAPAAAPAAAAPAAAPAAAVPAAGGAPAGDAYTSAASGLLAGGALETAISNICEMGFPREEVVRAMRAAFNNPDRAVEYLMTGIPANAGPPPPAAGGAPPAAAPAQRAPAAGGAPPAQAPAAVPAGGGPQAQPFNMFGGPAPGGGGGGGDADLPPELAALRNNPAFGMLRAAVAQDPRALVPLLQQLGRTNPELVQVINQHQQAFLAMLTEGGDDDDDDAMAAMLGGAGGGAGGMVVELSPEDEAAIGRLAALGFDRGACLEAYLACDKNEEMAANFLAENMFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T6I5</accession>
    <name>A0A835T6I5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_010802</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000043">
        <property type="protein sequence ID" value="KAG2438346.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T6I5"/>
    <dbReference type="OrthoDB" id="106784at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014891">
        <property type="entry name" value="DWNN_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033489">
        <property type="entry name" value="RBBP6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439:SF0">
        <property type="entry name" value="CELL DIVISION CYCLE AND APOPTOSIS REGULATOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15439">
        <property type="entry name" value="RETINOBLASTOMA-BINDING PROTEIN 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08783">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01180">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51282">
        <property type="entry name" value="DWNN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="DWNN" evidence="9">
        <location>
            <begin position="5"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="8">
        <location>
            <begin position="193"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="164"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="263"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="346"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="505"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="277"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="369"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="505"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="526"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="552"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="567"/>
            <end position="616"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2438346.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="671" mass="71993" checksum="BE31785675FD1823" modified="2021-09-29" version="1">MASSIRFKFRAELSYSNLPFDGHYITVGELKRLIAEKKGLGVDAANELQLTDATSKRDYDNDAEQVMKNSAVIVRRVAGAAKPKTILSSSTVPAPAAPAAPAAVPMTAAPLAAADLAPAHVDDEFGEDPYAKAAAVKQDEQQMMAFLAHAAQGVNLEAQLAAQTAPAGRGRGRGRGGFGAGGGRGGRGAGRECLRCGQLGHFISECPTQGDPVYDKRFKVPSGIPASKIQRNADGSLYLPDGELGELAANTSAFNKLAAMMGRGPAAPESGAGGAQGSAAAAVGAGEPSAPAAWQDPTHAAAALKQQQLQNAGGADGGVAAAQEQTQMQQMQQQLLLMQQRMQQLQQQQQQQTPEREVKQEPAQTAEPKLFDDDDHHGAGGTQPGAMQQPVKLGLGMVADDGGRQRSASPAPSRLTGSLAAGAQREDGTAAGAAAGGGGGAGRDVDHDGIPSWVADTGCSRHELSAVLPFLRNLLPGDMSMQAVFRAFASGRPLLRREFLELQSAERHAADRQRRDKDRDRERDRGRSHRSRSRSRDRRSKRSRSRSPSSRSRSRSRSPSKRHRARSSQDVRERERDREKERERAREKERERERHRERDRERAGRYHDRDVKREEGSPSLQQAGGGANARAAKRSRSPPGRGAGERAPSVDARTRIEAQRKVRRPVAAYQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T6K7</accession>
    <name>A0A835T6K7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Tr-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_010497</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">This protein promotes the GTP-dependent binding of aminoacyl-tRNA to the A-site of ribosomes during protein biosynthesis.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000039">
        <property type="protein sequence ID" value="KAG2439867.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T6K7"/>
    <dbReference type="OrthoDB" id="342024at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd04093">
        <property type="entry name" value="HBS1_C_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000204">
        <property type="entry name" value="Translation elongation factor Tu"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054696">
        <property type="entry name" value="GTP-eEF1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050100">
        <property type="entry name" value="TRAFAC_GTPase_members"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009001">
        <property type="entry name" value="Transl_elong_EF1A/Init_IF2_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23115">
        <property type="entry name" value="TRANSLATION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22594">
        <property type="entry name" value="GTP-eEF1A_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50465">
        <property type="entry name" value="EF-Tu/eEF-1alpha/eIF2-gamma C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="11">
        <location>
            <begin position="265"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="238"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="10"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="42"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="10">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="10">
        <location>
            <begin position="103"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="114"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="144"/>
            <end position="160"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="239"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2439867.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="712" mass="73694" checksum="8C82CD45846C1A9F" modified="2021-09-29" version="1">MVKGKRGAFYDDDDLDDGYDDDDYDDYYEEEPAPPPKKAEPAKTQVAGKQAAAQPAAKAVPAAAQAAAKPDPAVKSLHQPTYPVAPAASGSSPFQFDTPSPDDAVKAAQERKPGAVAPPATAAAPAAPSLPQNKNFLRPSPMMQQQKQQQQQGGPANGEAAADEAARRVASLGLASATSSGSVPEGSGTPAAGTRHHHPHVGHPEAPNALAHPGGLHGLHTRRPVTEYTMEPDLAREVAAATSSETPSTSAAAAAGGGGGAAHARPPLHLVVLGHVDAGKSSLMGRLLHELGLVSSKEAHKFQRDAAAAGKGSFAWAWVLDERPEERERGVTVDVAMTRFATNKFAVTLLDAPGHRDFVPNMIAGAAQADAALLLVDGSPGGFEAGFSEGSGGLHGVPGGQTREHAALARSLGIEQMAVVVSKLDTCGYDQTRFEHIRATLLPYLKSVGFKESALQWLPASGPLGENLVAPPQDPALRAWWGPGHPCVTDAIDAFAPRERAVSRPLRMPVSDVFKSKTGAVVLGGKLEGGAMRSGSKVVLVPGPAQPFTVRSLEVGGAATSLARAGDSCEVALVAHGGGGGGGAIDPSMVTPGAVLCHPDFPAVLVTKFELRIVVLDVPVPLLRGQAVTLHAHVAREEGHISALVALLDPRSGEVLKARPRCLTRGQSALVEVTSSRGLVLEEYGHYRSLGRVALREGGRTLAVGVVTQLLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T7L8</accession>
    <name>A0A835T7L8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pseudouridine synthase RsuA/RluA-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_012817</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>a uridine in RNA = a pseudouridine in RNA</text>
            <dbReference type="Rhea" id="RHEA:48348"/>
            <dbReference type="Rhea" id="RHEA-COMP:12068"/>
            <dbReference type="Rhea" id="RHEA-COMP:12069"/>
            <dbReference type="ChEBI" id="CHEBI:65314"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000064">
        <property type="protein sequence ID" value="KAG2433115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T7L8"/>
    <dbReference type="OrthoDB" id="428658at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009982">
        <property type="term" value="F:pseudouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000455">
        <property type="term" value="P:enzyme-directed rRNA pseudouridine synthesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.2350.10">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020103">
        <property type="entry name" value="PsdUridine_synth_cat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006224">
        <property type="entry name" value="PsdUridine_synth_RluA-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006145">
        <property type="entry name" value="PsdUridine_synth_RsuA/RluA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050188">
        <property type="entry name" value="RluA_PseudoU_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600">
        <property type="entry name" value="MITOCHONDRIAL RNA PSEUDOURIDINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21600:SF88">
        <property type="entry name" value="RNA PSEUDOURIDINE SYNTHASE 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00849">
        <property type="entry name" value="PseudoU_synth_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55120">
        <property type="entry name" value="Pseudouridine synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01129">
        <property type="entry name" value="PSI_RLU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="4">
        <location>
            <begin position="221"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="domain" description="Pseudouridine synthase RsuA/RluA-like" evidence="4">
        <location>
            <begin position="382"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="133"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="215"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="356"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="434"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="573"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="136"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="168"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="228"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="361"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="459"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="608"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2433115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="617" mass="62948" checksum="3136AB61AD1E09B3" modified="2021-09-29" version="1">MVRIDTGAWPAQNEGFVFRDWIKSRHAGQGLAHFYASVHPASASPAEWEARIRNGQVAINGVEVLDPTRVLRVGDVVSYRRLPWVEPPAPCHVDVVYEDADMVALSKPSGLQVLPAAMFHQRTVLSLLRRHYGDSDSGGGGGSRDGGGGEGGRAGGGEATHTANAAAGAGGSGGGSSGVEATAGLSLGSEEAVGCGGETGVCSCSYTGPAAGGAAQVTKQEGQHRQQKQPQSQQLQRQRLAVPAPVHRLGRGTSGLLLCARTPEARRRLTELMTSKTVAAAEAAAAAATTATAAAATAATAAAAAQVAEQLATASLPTASSDCEPSSSVAAAISGVACGRGRTAAPAASVSGSAAAACCETPPPQPQQSPPQPPPPPPPPLRKLYRALVQGRVPADQGRVDVPIGPIPHPGVDRGLFAVTPDGKPAASVWRVLERRGPTASQRPPTSPTPARPGGGADSGAAGAAAAAADVGTARTAGRGATEGGERRADGGDAAEEECTLMEVEILTGRPHQIRIHMAALGHPLVGVDAAALADEEGGGGVGELEYGGYGRPGDCGYHLHSLELHLPHPTSGRPLVLRAPPPPLLMTRQERELELEREEEQEGEGLQQRERGQGER</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T7N3</accession>
    <name>A0A835T7N3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_010309</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440422.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T7N3"/>
    <dbReference type="OrthoDB" id="541739at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2440422.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="361" mass="38398" checksum="2698DA7BB5BDC92C" modified="2021-09-29" version="1">MRASQSPWTLQHERQSTAALASSSSSLAAAAAWQASVQQSESTLVEDWLAAMHQVDAEARNLCSGLLSRNPTLLYRDAARTTGVVQALVEATRQRHLLRPYHMQDAHILALVDRYTPESLRARLSELHRLVWQKLDDSNTPALFAARTSLDMLDLDAKALALKAQALRALIPEFLPSTVLRACPELLDVQVDDLPQHVRRAGDVVVVGAHTQAELVAPNNVVIVRSRVIEPVQAQQPQPQAAAGGYGASGLASPGSSPPLPVSPFAAAAAGRLLRTARCGAAALLRDTAPATSGAAAAASREVTKVFCNTRQLVYAAGEAVEVRVEDPHKAQEDLSAACRMAVLQRLSLAGQASGGHVRVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T902</accession>
    <name>A0A835T902_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ADP,ATP carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011721</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000051">
        <property type="protein sequence ID" value="KAG2436009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T902"/>
    <dbReference type="OrthoDB" id="543971at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43596">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43596:SF1">
        <property type="entry name" value="ADP,ATP CARRIER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="21"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="90"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="197"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="228"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="388"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="456"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="329"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="346"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2436009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="553" mass="57651" checksum="584CF5436A620602" modified="2021-09-29" version="1">MRPASWFSYLYGYALSPHEAVTARHGFTAFFFVLASYFILLPLREDVALTLGPSVLPSLFTASLVVTAVAAPLVTSYVVNPTTGSRAIGFGRLCNVMCGCLMALWLLLLITSPNPWAPARLLRLLLVWRPPQRLPAGHPALAPPPPDDPTQHLTYSWYGNAVRVCFYVYLSLQSLLSTSTLWAVCADTFSPATSTRVYGFLGAGATLGQLVASATALAFGAACKQTGAAGASTWLLLPAAWLLLMAARACRAMSGRAEKAGGLIATSTSTTGHPAAAIFSSSPSSSLAASPSPLSHQHQHQHQHQQAALVVVASASGNGLQELSERFKGGGGGGGGGGGGSPPPNSSTSHHSMKNNNSNNSNSNSNNQNHNAPPHLLEGFHLIAASPYLLLACAFLALNYATSATLYFLRAAIVSRAAWLSGSDSRIAFFAALNTASAGVIFAAQMLVTGRVLTSLGVAATLLIGPAVSLVGMGLIGLAPSAAAIAGVEVVRKVVAYSLSRPCREVLFTVVSRREKYTAKVVLDTVVQRLGDTAAAALFELVGEWDRERGGGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TBC9</accession>
    <name>A0A835TBC9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_009835</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
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        <property type="protein sequence ID" value="KAG2442043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0A835TBC9"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08215">
        <property type="entry name" value="STKc_Nek"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="4"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="304"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="435"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="491"/>
            <end position="554"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
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            <begin position="334"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="438"/>
            <end position="454"/>
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    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="501"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="525"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
            <begin position="538"/>
            <end position="549"/>
        </location>
    </feature>
    <feature type="binding site" evidence="9">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2442043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="700" mass="72818" checksum="EE72B38F05C3376C" modified="2021-09-29" version="1">MDAYQELKLIGKGTYGKVYKVRSKVDDDVCVIKKVQFDGTPQTEAEAALREGQVLSLLRHPHVVPYKEFFKHTDGDLCLVMAFCEGGDLFKYIRELRDQGKTVPEPQVWAWLVQLLLSLSYIHSKRILHRDVKTQNIFLSGGKVLLGDFGLAKQLQRTFEMARTPIGTPYYMAPEIYEEQPYSFKSDVWALGCVMYEMMTGRAAFAADNLSRVVLRVIRGQYDPLPDTYSSALRMVVTSMLCKEVRARPDANQLLTVPAVVPHVQSYLESLTAEGPSGWATWRMKLPLTAMVQMSEALEAAGVPFGGRRSHTGGGGTLPPSNRTSVSGAAGPTPQLSLDPEPLQEEPSLSPEPPAGGGGGLAPATPEQRQGGSAPYNGVVGGQVVKLPPLPGVKPVRTPYGLATPFMGGAATPPQHYAELQVLAHQVMAIRTSQCGDSAGNSESGAAAAGPDGALEGGGAGTTAGLAPGDEVPEVVKALDRTLIKTLEVARRATEADSGGPDAGGGGGGGGGGGIDEAWLSAGLPQGGFGFGGGGFGAPPPPAPAPKPSKPSDVVSLPPIARPRPISAKGLLAAGGATSEPPTPSANAPARAVPYGVPDEGFASLSHVSLHAQSLVARRANLEAYCGQLLGPDLMEQVMQAVSEAQKTSATLGGAGGVEAAEAALARQLDRLLAGGGAAGQQLRAEVGPLLEELALLHVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TCB1</accession>
    <name>A0A835TCB1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine phosphatase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_011870</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000052">
        <property type="protein sequence ID" value="KAG2435576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552813at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0008579">
        <property type="term" value="F:JUN kinase phosphatase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14498">
        <property type="entry name" value="DSP"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Protein tyrosine phosphatase superfamily"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000340">
        <property type="entry name" value="Dual-sp_phosphatase_cat-dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029021">
        <property type="entry name" value="Prot-tyrosine_phosphatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016130">
        <property type="entry name" value="Tyr_Pase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000387">
        <property type="entry name" value="Tyr_Pase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020422">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL_dom"/>
    </dbReference>
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        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DUAL SPECIFICITY PROTEIN PHOSPHATASE 19"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DSPc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52799">
        <property type="entry name" value="(Phosphotyrosine protein) phosphatases II"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="TYR_PHOSPHATASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50056">
        <property type="entry name" value="TYR_PHOSPHATASE_2"/>
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    </dbReference>
    <dbReference type="PROSITE" id="PS50054">
        <property type="entry name" value="TYR_PHOSPHATASE_DUAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tyrosine-protein phosphatase" evidence="4">
        <location>
            <begin position="30"/>
            <end position="172"/>
        </location>
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    <feature type="domain" description="Tyrosine specific protein phosphatases" evidence="5">
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            <end position="153"/>
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            <end position="237"/>
        </location>
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            <end position="1921"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="2003"/>
            <end position="2012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2015"/>
            <end position="2044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2057"/>
            <end position="2069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2118"/>
            <end position="2144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2165"/>
            <end position="2178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2225"/>
            <end position="2245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="2246"/>
            <end position="2260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2261"/>
            <end position="2276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="2290"/>
            <end position="2302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="2327"/>
            <end position="2346"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2380"/>
            <end position="2389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2498"/>
            <end position="2517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2561"/>
            <end position="2572"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2435576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2626" mass="248252" checksum="13556A916B83373D" modified="2021-09-29" version="1">MQPAGNSFWHAKAAIAKQFARKPPIQADTRDTLCEIARGLYLSSCHLEAQRDTLKQANITHVLQVGTELTPTHPGLFLYKNIPVLDLEEEDLVKYFQECFRFIDAGREAGAVLVHCAAGISRSATVVIAYLMAHGSLSLEDARSAVKAARPAINPNQGFLLQLQLFQEAGFSTEGWQPWNLDRFLQVRSAAYPRAEAVPAGNADVRGACEVAPPELSREESLSAANSPVQSPARKGRPLRPVALLAAGAAAAGAGGGGGGGAGPSRMGVVAASLASGEVGGADAAAEQAAAATETTGGVSSSASGSSMTGARVSASGGFGRAGVPLPLPLPLPLLPPPPPMGLVPSPLTSPHKLYPQQQHQLDAMGAGPRSSLHDQVWTRPYAHSAVHAAPPPPPLPGHGPRHTISGIPDASSSSQWAWAAQRGQAPGAAAPQPSAPPSASLLIAPPAADAVEEGSGAAALGLDGAGGAGWTGVAGHGSSYARPPLSPPPMGFGGGGAAATWASSAAISPAGAVPGSQLPPRTGFRASGPGGRASTSGVWSVDQAAVRGTSAYAAAAAAATTAGPPAWGSQAGTGISTWGTPNYVHPHRQHASHSQPPQSLSQQGFPPQQTMSVPLQLSGGGGLPAGAGAAAAAAAGLSVAVAQPPIAAPELSQEHGSAGQGASVAAVAELQEESSAGGSASGNEGPATAAGRRHHAPRRSMSDSLPGMLARVLADAGAGAGSGELSTSAAAAVAGAATVTGATTAAISAGGDQGSCQPYRMSDAGAGAAMPRYPRVSGSGTGMVPPPPPPRQSYDGSVGGAEVWVGHVSTGGARISMNGSGGSLLAGVGADLAWGAPASPPATLPGVPGTAREGEGRAQGAEAASASTPGLTWAQTPVLTPAGLDRTPSKAMATPKMRAAAAAMAAAAAQLPPSASPDSMISRTVRELFGAASGEGLAATAGTTEEAEGQEADPTGAREALLAMTAPGVRSDADLVVSRSNSMGGAAAGLAAAAAAASASASGSASGSAAAAEGAAGAQGPGRGGRGGASALAAAGGAAATAAAPGGGGKGASRLATATFADSGVGLGPPRLSEGGYALGSQPSVDGRSNGGSSGSAGGTGTGHGGTAAPAGAGPGLGRVSAPSAMAYNTSASGLAAFLAPQARTEAQPSAGGTPPSSAPVPMTTGPAAPGSQPLDLPVKRLSIRSRAAGSSAGGSSAAGDSGAEVGTPIHKRVLRSLTSLLRVGGGSPGSSAGGAVSADAGSEASSGGGAGGGPGKTGGAPASGGSSPAAEEQARAAPRRRLWSSTDNLASGAAAAAAAAAARASAAVPTAAAPSSSAGVNTADSGADGAAAAAAPPMLVDDATAAAAASRGAGADVLLPRRAQPPLLAPDSIPGSPALFQPAVGVAAGQHGDPADLPPRRRSDTGSVASPTTTMIYGAGRGGGGGGLGAGAGAGGGAVGGPHSASGGGEFGPYGPGGLLHRKPSRSGNASPAHTEPGGMSQTQAQAPQPLPLPLLPRPQVGVGMRPRRSDGGPVTDGAGATLNTSDDGWHGVAAAASVPPHSWSNGGAAATASSIPDSSATGLISPARPLAAGSADAPPYGGASGGGAGGHPAPMGLLPDCADVDDQASWGVDLDSLPAAPFRWAEPEPAAAPGARSSAGPGAGASGAAAAAGAEAAAEGGWAPGLPGFPARPMSVDGSAAGPPARVATAAAPGFAQQGRGAGRSVGAVTSSSQCSASSTAFMSASAAAAAAAAGGGGGGPLTAVNGGIAVPEPGVFNNDTLRPAMLEPSGQLSPPAASPAGAAAATRPPPLDMAVVPPPPLTAVALQAHGGGAAAVAAATAGASVSGAMARRPRTSYSGALSMMVPPASMAVGGRTSGIFPPSPLPSPGPVGGASGGGASAASAVPWTAPGPGVTSGPPSTTHSATASPLPSSQQHFGGSEAGSPSPRQRPQLQSGGGAVGEGGASVLVAGATGASSGGPDGRAVWGGSRATADISSMMSELPASPAQQPGSQLRSRVAPRDHARQPRSDGPAGSAAPRTSSGSGAAGAPRSLPPAAGTSAAVAATARAAAAPRSTSAGSSALPQSGGGLGAAGGASIAAAAGQPAAGGDARPGRSDDGFDITRIWEHLRAVRQQQHQELQQQQEQQAAAAAGAGLHSQSSPIPPPIFRSEGGASDTSTVPLAVSSPNALSSSSNATTALAISSSPTFAAGDGAATAAAALAAASAAAVARTSNGGGTVAGGSATARSSTSREAPASAPAGFAGGGGGGGRQGGGFASPASSSAASSSVVSPRAPPAMMRESTFDGSGGGGGGGGGGTADVHAPAVLEGSPSPSHRVPLRPARGGGGGGGAGAGNGGSGGGRPDASLLRPVLGIRRLLPMPSPSCIVATPTGTPRAVRSGSVGAATSGGGHDGAGPADASGTSHPPRRGSVDSSVRVKAAAAAAAAASLVAMLGLPPQAAEDTSLPPDTFGVATAVAPAASAVASPFGGTAGLPAFPAVGPDADAGQQLGAARSASSVLPSPGGSSSGAGSARGSLRAMLPVELTQQQGDTAAAAAAANVPVTGTAATAATASEVASGAHSSSVASGANRSALLPSRSTSMEQSAAAAAAAASPMWSPSAVRSPCVVAGSHSGSEDGAPQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TDC5</accession>
    <name>A0A835TDC5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Anthranilate synthase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_011650</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000050">
        <property type="protein sequence ID" value="KAG2436146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TDC5"/>
    <dbReference type="OrthoDB" id="1865897at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006805">
        <property type="entry name" value="Anth_synth_I_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04715">
        <property type="entry name" value="Anth_synt_I_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00095">
        <property type="entry name" value="ANTSNTHASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anthranilate synthase component I N-terminal" evidence="3">
        <location>
            <begin position="106"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="2">
        <location>
            <begin position="326"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF04715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2436146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="556" mass="59336" checksum="B2A2BFF39FF61789" modified="2021-09-29" version="1">MSLLGQRPQLGARDATSSSRRKLVAPCSQRVARAAFGRAFVPVRATATLDSSAATHSASVGSAHHASSGAAASANGASADAGFQKFLDAVKSGANLVPLSQRIFSDHLTPVSAYRCLVPEGDSELPSFLLESVVNGDQQGRYSFLGSCPALEVVASRDRVVLLDHDKGSRTVTTMADPMQLPEEISRNWRPAAVDGIPNVFTGGWVGYAGYDTVRYVYGSKLPFDSAPEDDRRLPDMHLALYYDVVVFDQATKIIYPIAWVPVGEQEASDPAALRAAYEAGRTRLAALTAKLAAGPATGAGGLLPGAISLDLNKRPALPENSNMTKQEFMDAVGATKEHIQAGDIFQLVLSQRFERRTFATPFEIYRALRVVNPSPYMVYMQARGCHIVSSSPEILCRVDNSRVVTNRPLAGTRARGKDPEADKALEADLLADQKEIAEHVMLVDLGRNDVGKVAVSGSVVVQKLMEVERYSHVMHISSTVTGELLPALDSWDALRAALPAGTVSGAPKVRAMQIIDELEVNKRGPYGGGIGHVSFTGRVAGCGWAVGWVGGWVGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TFG2</accession>
    <name>A0A835TFG2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nudix hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011150</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000045">
        <property type="protein sequence ID" value="KAG2437775.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TFG2"/>
    <dbReference type="OrthoDB" id="185493at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.79.10">
        <property type="entry name" value="Nucleoside Triphosphate Pyrophosphohydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015797">
        <property type="entry name" value="NUDIX_hydrolase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000086">
        <property type="entry name" value="NUDIX_hydrolase_dom"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55811">
        <property type="entry name" value="Nudix"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51462">
        <property type="entry name" value="NUDIX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nudix hydrolase" evidence="2">
        <location>
            <begin position="79"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2437775.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="235" mass="26181" checksum="7D883F3CD4756C7E" modified="2021-09-29" version="1">MSAPSAEVAAGTPRSQAGGNAGAAVHVPAEHPWHNRFEVKEDRAVHKRYMTMFDRTVEFTSESGQTQTVQYDVVGHPQCSFVSAVAFPFHPATSTSPAQVTLVREYAQGPNALMYTLPCGGFEPKRHANLRECAVAEMREEAMLVGGEVVDLLPEDHPGQSELKWSRNRFKPFLFIDPQPDTSGHAERDAEEHTIQVMRVTIPELHDIIRTGQLMMLSVYAAFLSLEVLRERKLI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TGK6</accession>
    <name>A0A835TGK6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Steroid 5-alpha reductase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_011026</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000044">
        <property type="protein sequence ID" value="KAG2438330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TGK6"/>
    <dbReference type="OrthoDB" id="67965at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010721">
        <property type="entry name" value="UstE-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251">
        <property type="entry name" value="3-OXO-5-ALPHA-STEROID 4-DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32251:SF17">
        <property type="entry name" value="STEROID 5-ALPHA REDUCTASE C-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06966">
        <property type="entry name" value="DUF1295"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50244">
        <property type="entry name" value="S5A_REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="124"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="149"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="189"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="219"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="276"/>
            <end position="293"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2438330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="38103" checksum="C6E16BE0FC7046DF" modified="2021-09-29" version="1">MKHQVALNLTRKLAQPSKEGGVTGLSLLARRSLLTSRRLGLLGRGGRGLLGGGATVGALMWQDAGAAIAHSLHTSSGLLSSSASSLFTGRLEMGLLGWLAVDVAINWAGWAVASAFKTEKFYDLLGSVSFLTLTAGSLVAGGASGARKFVVSGMVMAWAVRLGSYLVTRVMKTGGDARFDEVKHQPGKFFVYWTMQAVWVFVTLLPVLCINGGRSPVPLGPLDALGIAVYGLGMALEVTADWQKAAWKARPENKGRFIDEGLWSLSRHPNYCGEMMIWWGVFLTCAPGFGAAWQYVSVASPVVVMLLLRYVSGVPLLEEMGEKRWGSEPAFQEYKARTNLLLPLPRFKDTHVN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TIP6</accession>
    <name>A0A835TIP6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_010910</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000043">
        <property type="protein sequence ID" value="KAG2438455.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TIP6"/>
    <dbReference type="OrthoDB" id="10053569at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004502">
        <property type="term" value="F:kynurenine 3-monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070189">
        <property type="term" value="P:kynurenine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002938">
        <property type="entry name" value="FAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46028:SF7">
        <property type="entry name" value="KYNURENINE 3-MONOOXYGENASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01494">
        <property type="entry name" value="FAD_binding_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00420">
        <property type="entry name" value="RNGMNOXGNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="1" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="461"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="510"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="4"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding" evidence="4">
        <location>
            <begin position="344"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2438455.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="536" mass="55821" checksum="22774DD1E9B7F659" modified="2021-09-29" version="1">MPSAIVVGAGPAGVLTSVYLAQLGYAVDVFERREEPSQAQASSQHSYPMVLANRATVCIAEAGLQPACCTEPTARPCCGHYSLGKLRGGGDPKSLGPEMVTWVVDRVGLAADLLAEACRVYPDRIRFHFNAALTELDLAARRVVFSLAQPNGGSTSTQEVCGYDLLVGADGASSGVRAAMAAQLPPERFSAELLYQSVVVYRTFHGLPRTRPAAPGPDASAAPERPVPVPVEELVPGIGEHLPKQHLYWYDNRTGPLVTFWINEAGQLDGLVSKVTDWSASALSSLIRSVHPAIPPYLVDGIVEQVCPKQPSAEASSAAPESAPAGGGSRFGCVVRCRPFHAAEEGVVLVGDAAHPVTGHLGQGANMALESARALAAALRRFGPGRQAEALAAYSAERAADTAACQHLEMSMAAFVLPPVYRPGGGKAGKAGAKGGPEEGGAGAAEGAAGSAPFSLGFRLYAAWLIMGSMMVGLAGHKLAPAAFPLPIWLMAATRDSRLRYSVILQRARLMAGGLVLAGGAAAVASVALAVRWWRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TJ19</accession>
    <name>A0A835TJ19_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_010574</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000040">
        <property type="protein sequence ID" value="KAG2439695.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF147">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="13"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="450"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="553"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="787"/>
            <end position="818"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="843"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="924"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1063"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1215"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1315"/>
            <end position="1342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1366"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1544"/>
            <end position="1564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="13"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="34"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="453"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="481"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="558"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="787"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="865"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="926"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1066"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1091"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1239"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1366"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1403"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1546"/>
            <end position="1555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2439695.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1670" mass="163580" checksum="8E11E3412C590643" modified="2021-09-29" version="1">MDDDPEAYLEEVLGEDEGEDAGEAVTLQQLRPPTKQEEQREEESRKKDKAAAAAKAAKRKKPLPPIRVNLSACKYEVLRIVQRKLGWKEVGDDDDWELYWTDTSVSIERIMKLTKIQKINHFSGMLEICRKRAMARNLMKMAKAFPQHYDFFPRTFILPSDREDFLADVRSRGKKQVYILKPDAGCQGRGIRLVQGGKEEVVTRVLTEMATPNVVAQHYLVNPMLIHGYKFDLRIYALVLSCDPLRVFLFHEGLARFCTEKYSPPKASNLDVAFMHLTNYAVNKKNEAFVSAAAAAADGSEDASKWCLAQLRHYINSTGASYDKVWADIADLIIKSLCSVQPVLRNNYRSVLPPDNDGFSCFEILGYDVMLDDGLRPWLIEVNHSPSFNIDSPLDLAIKEELITQTIDLVRVDPKLISKAKKAERRAAASRLLEPMHVKKQPAAAAAAAGPAAAGGGGGGGGRMGAGAAAEEEWGGGGGGGKEREKERDAAGKPRTPEEYEAWRAKVLAARERYEAKHAGNFTRIFPSPDPAKQALYEELLKGAQEIYQASFQARSAKPAEKKKEELETESQKAERLRAKAHRDKLAQMAVERRKAKLQLAAAANGQAGPGAGLPAYLSPPPFLAPPPAPGSSMMAVGGGGGAAAGPHYAPLLPGSSTAGAFAYGDASAFQQHQLYMQQYQQQYGAAYYTGPMPLGGGASGGAGGIGSRVSEVYGERSDVFGSAPSSRPISAMSAASGAAAAADVAALSGQLAAAGLLHHGGGSGGGGHAPLMRIYSGHMARAASASAAGRAASPAGGHPAGSGSGRNSPSLAAQQQHAALMQQQLQLQLQLQQQQQTTFLQQNQQQGALPPNPFLGGGASTFGPRRPASAATSAAREAALCGPAPAAGGNNAAPGGEWGHHYVSDAAANAALAAAAGAGVAAASRGGGGSGGGGGGARAASPATHLTPGAPGAGAAGGNAVVAGAAAGAALPFGRTSLLGHGSAAAGGSGGGGGLPAATALQQLQQLQQAAAALALSQSAGAAAGGGGGGGPGAGAGLGCAVGGVGGGHGVTVGSAHNHVKHAHSGAAEAAGPSAGCGSGLNSAESWQGEGPGAGSAPGGAGPGRGGGGGGGGGLLGSRPPSAATASLRDKLQPGGPAAASAALAAAMTASAGAGASGFGANSGLSRRQSLSMSATLANAAAAAAAATNSWDAAKAAAAGQDAAAALQYLSSRPRPLSAGHGLRPTSAGAGRRSPSPLGGGGGGGGDSGGGSAAAVAALAALSANGAVASAGAGGPAADLYSSQPYGGTGAGASNHAAVSGAVAHSPKLAALVRTSSNPTGPLSPRSPSVSGVTVGASAGGGGGGGGTTVGMYGSMYDSVGSGAGGGGAGAGGGGGGAPGRVYKQTRVPGLPTPHMAMPLKGGAASAGPPRSAAAAAPAPGLPTYDEDAGGGPDSGALTYQPLPMPMPDALAAVGGGGGGGGGGGAVIGSRHWSATTASIGSPPAPSSTRQRSFTAAASASASVAGAGAGAGPGALGGGGVNSGPLPGRLPVYPPLGGGYVGQRATGAPSSGRPGAAGSGKAGVPAGVRVNSALAAVLAGGAAGGAAAAAAAGLVVSSGSPGVARGGGSGGGGGGSVVGVGGVLEGLQGLQVSALGLGLGPDLDSQMRNAALQSLNRRALTVTGKKVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TKR9</accession>
    <name>A0A835TKR9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_010281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440391.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TKR9"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02373">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="2">
        <location>
            <begin position="621"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="810"/>
            <end position="865"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="968"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="969"/>
            <end position="991"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2440391.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1022" mass="106160" checksum="C501EEB80192CE46" modified="2021-09-29" version="1">MRVGASVPTSGQTSSEPGAVVEPAGVSKAATRKLRENALKELDSAAHSLVTGLLTEAKLLPGCNGATLAFARLYRPELREALLWLSRSLGLGDARSRGGGVSAARISSCLAPTCPAADADVCNAVSSQMDCFTRQCGGDGSGSFPAQFSLPATKGCDCSGCTLGLDAELLARMATMRPYFAAAAWELLLNYAAFIRERTCGPGSSGGSPAAVVAEMQKVAAGDCGGGLFHPDFVRHQQQLLLAQFRNPDTSVVDYGCITCDVCCRRVGVGVYSQRRHAAAAGGDVCHFCTRHKACVLGPDAADDAQFVSLLTVREWQALLVAASVSPAHAHLLLPPKDIDAVCKDFLPQYLPATAVGASVSPAACRQPGGGMPPAAGTGVLTRAVAATATAGVRVGRPGERVTAFPADIQDDGRHVHVLKPECVDPTDAAAALAASKAVAHRLAAGIPSVLAMQDSLLPPAELAKELRDAGAAVSAAGQVEQSSISFRDRYGASAPALLGGEPHAAPAVGPGAEEAVAPTYSVTFTGPGTAPVPKADAPRPAADLLGLLGKLVAGSVTEDDILRHIYLPPPPSRSQPASSRAPPALQRLKAEVAAAIRGGRLIAGLPLGVKVVNFPSDCHLESLIPDLARRVKRAVARRLRDLLGSDMVQLLPPGAYDRVKMYVNLALAVTDAHVDDTAAWNWVVWAASANPDDVVATWLFTHPTATPLVHAMLERLKLGTNRGEADDGAFAFRANLSLSPQDFIRLCRESGIPVTVVHQRVGDLVVVPPNSVHAVWTHCPALKFAADYMPAFGLHPCMLLADAMGQQEASLRLSPAPPQPSSPSSPSSSASPAPQPGTKRPSTGDQSSSSGGGADGGAKPSKRPKVAFRLDLSKHSLRKDVDAQGHNSDRAGPQLMLEMFLRSCCDDVCAKMAAAGAQLHVDWGVVLRYQERQVFKLTDPLHAPPHKQITSKGPFILDSAAMVPAGEAGKGGDTGGKAGKGGKAGKGGKAGQHHDTSPTMLYGPFSVARYIPPPPVWFAAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TKU4</accession>
    <name>A0A835TKU4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Patatin</fullName>
            <ecNumber evidence="8">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_010319</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Lipolytic acyl hydrolase (LAH).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="domain">
        <text evidence="8">The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the patatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="8"/>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440436.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd07211">
        <property type="entry name" value="Pat_PNPLA8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045217">
        <property type="entry name" value="PNPLA8-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24185:SF1">
        <property type="entry name" value="CALCIUM-INDEPENDENT PHOSPHOLIPASE A2-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13855">
        <property type="entry name" value="LRR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00364">
        <property type="entry name" value="LRR_BAC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51450">
        <property type="entry name" value="LRR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="5 7 8" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="6 7 8" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="PNPLA" evidence="10">
        <location>
            <begin position="832"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="412"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="524"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="564"/>
            <end position="583"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="588"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="720"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1223"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1407"/>
            <end position="1460"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1497"/>
            <end position="1552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1713"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1824"/>
            <end position="1844"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2021"/>
            <end position="2062"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="7">
        <location>
            <begin position="836"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="7">
        <location>
            <begin position="868"/>
            <end position="872"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="7">
        <location>
            <begin position="1089"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="412"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="428"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="457"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="569"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="730"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1223"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1237"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1262"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1407"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1504"/>
            <end position="1524"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1734"/>
            <end position="1746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1827"/>
            <end position="1836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="2025"/>
            <end position="2047"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7">
        <location>
            <position position="870"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="1089"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2440436.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2122" mass="207314" checksum="6529E577AE30E357" modified="2021-09-29" version="1">MHPPRPACAPACACACSCCEVGSWSALANMNLSSCGLASLPAAIGALSSLRILRLSHNRLAALPPELSGLSNLEVLAADHNQLTALPAELRRCTALRHLELEGNRLATPVLDLRALSGLVSLQLYGNPLEYLPELSPASALRSLSLANVRIMADAAYTRWEVEVAALPYMSRVSHKLAPLFKLTFRRSSCQHPLLAGALGRISEDRSNCELMAREETAIQQLVLMALSEAPVVGEQACRTLGALAALGLATARRLLAHDVQSTILTLLRSPRRASKLCGMGLLSSLAAASEAVAVELLGRELLALLADCVAAPEPDARAAALSALANLAFCRENKLKIRRAEGLVARLVELATAGAGAGAGPEAAGAAGEGPGVGLGLAEAAAAAGGERAQALSQLAEQQGLMEGQQQRLLAPAPAGAAAPGAGGDASGTAAAPPLPASLAESGLTSPAGVVSSRGSPVQPAPVSSPTAPAAASAPGRRPAAAAAVGQLQQQLASAQAPTTFTLPASAAAAAAATNAAASTPLASARPLSTGSGATPPASASATAANMLPTGMAPAPVAVRMPMRASGPGAGTGEGGAGRLSDTGAAAFSSLLGSPPTASGGGGGGGGFLLSRQSASLVASSPTSASTGGALGLGGGGGGAGASLSGNGMSVGGAGAAAGGAVAGAQGGGGDVLSPPLSTRPLHHSASTPAAVNLLASASAVTSGGGAAATASTTLVAGVPSLSPPRLATGGGGGGGGGGYGSVSAPGLPSGVMSPTSPPAASDAAATAAALAGGLPAAIALAPPRLVPEVVAAQEPSRLLAIKVLAILGENEVVARAVGTPPIRGRGLRVLALDGGGMRGLALVQILRHIEKRTGRPLHALFDLVVGTSTGAIVAVGLGVFHFSLDQCESIYTGLGHKVFNQAASKSGSVTPREELAMAAQAQAAAQAAGAAAAAAAAASGGGAAASAGGGGGAEGGWRDSLFRVVRGTSTSLRVAVYGFKHDASTFEELLRQMCEIKKLGCMGNQMIDAAALGGPKVAAVATLVSVCPVTPFLFTTYELPPEVEPLAAALRAGPSSSRHLIWQAVRASSAAPYYLDDFLCGEDRFQDGAATANNPGILALQQARLLWPNTPVEALVSVGCGAAPSVRREKGAHAMLDTGAVLVDAATSPDRADEALSLLLPLVPGCRYFRFQPVHERCAMELDDVDPQHWAALQAAVDDYCVAHGSRFDEVANLLLTALPPEPPQQQQQLDQEGGDGGSEGGGELGGEQGDDEEWEAAGAGAGSSGGGALGLDAQPLSRVPRIRLGARRGFLLLESPEAPAAAAAAAAGACAGAAAAAAAAASPSEPLSAGGSTSGHQLEPHQPQIAAAAAAAAAAAAALEVAVLEALSRQPHLLRRCDVAATAADEPLAASLVAGYLHRLQREREEREREEREEREQAAEAEAEAGHARAEQAPVGSSAATAGPRGQGEGAHRAGADVVPRRGASGVAMPASSTADAAAVAAAAATAAAAAAGADGVSSSGSGGGGSGGGQASAGSGGGAGSSSSSVGPTRSGHSLLSPRGSSFRGWASTSRGGAAAAAAAGLPSGGLEDAAAEVATAAAAAAAAAAAAAAAVDSGVADAAVEAAAVAAHDSGSVAAPAQQQQQQPSSLFEYFFGSTSGAAAAAAAKKPATTPVASLAAVGATSAPPVPAAPAPASAWASTAAAAAAAAAAAAAPPVPLDKVTGAGADLAASHPVRGGGGGPAGHPLQIEAGDGSSAASPALASTPRAAATAAAAAAGGAPAVAAGAPARAQIAPPPRAALLLGAILADAVERCGLLHLSLPVAAVPAAATAAAAAATAAAGESEGRAEKGWAVDDSGGDDVDGEELEELALVTGWRRDVVAVVEPGPDADRILRRLGHAHPTASALPSAPAPTLGSLLSAAPGGQLRDARRCVSYSLLARQEVWHGGRRLTTLLLQVTRPAAALRPAALAALSRQLGGLVVTAASPLPHTITAALLRAGARAVVCPDRPILASEGTVPHPDGSAHGHVPRPLATRESISFGGAAPPQQQQQLQLPGQAAGQQPRSGALGQVSEEEGGGRMLEQAQEQAQEPGGATAAACFYDVLVREMTCRGASVMEAISAAERSCPALRGRVALHHL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TLU0</accession>
    <name>A0A835TLU0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_010068</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000036">
        <property type="protein sequence ID" value="KAG2441225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TLU0"/>
    <dbReference type="OrthoDB" id="544035at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2441225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="295" mass="28965" checksum="A9C679766FAE95EA" modified="2021-09-29" version="1">MRVCRPASQVLQGRLFCAGSRLDQATRCLLQPASTGSSGAATCGADAACSYLTAAQLAAALAAAPAAAAYLHLASLASFNEWPLPEGSGACVAKWLTQPDTVAALGRTAAANPAGWLLQPDLVGSGCSSTLRVANISAAPEMARTRAAVAAAAAACQSAGSAGGADGCAAAAAGCDWSGNAGGNSSSDVGTCSVGTPALLDSLFDPTDAWVKAQDQATALCTARTTKSSCAAAGSILVDPARLNTWRDVLADGGADWNLRDGGGAGSMAGGQPPPLLRWVLVAAALVLAGMSAVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TM62</accession>
    <name>A0A835TM62_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_009284</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443209.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TM62"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48038:SF1">
        <property type="entry name" value="RIBONUCLEOPROTEIN RB97D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="62"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="107"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="121"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2443209.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="225" mass="26426" checksum="2BB5BA1331050FB0" modified="2021-09-29" version="1">MMLDPLLTTSSALPPLCSPHVSIRRPRGFGFVEFKETRDAEDAMYNLDRSIVNGREISVTFSREGRKTPRDMMRIESKTKGDDRRDDRRRSRSRSPRRSSRRDSRSPRRSRSRSPRRSRSPRVDRGRDRSPRDRSPRADRSPRADRSPRDRSPHDRSPRADRSPVHAERERSPDRDRERVREDSRSPPPRERSPAPRDRSPAPRERSPSPRRDSPPRDDYAGDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TM66</accession>
    <name>A0A835TM66_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ataxin-3 homolog</fullName>
            <ecNumber evidence="4">3.4.19.12</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="17">Machado-Joseph disease-like protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="23" type="ORF">HYH02_010117</name>
    </gene>
    <organism evidence="23 24">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="23" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="23">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="14">Acts as a chain editing deubiquitinating enzyme that binds and cleaves 'Lys-48'-linked polyubiquitin chains, with a preference for chains containing four or more ubiquitin molecules thereby modulating protein degradation by the ubiquitin-proteasome pathway. Probably by regulating the IGF-1-insulin-like pathway, regulates lifespan. Regulates germline DNA double-strand-break repair and apoptosis in response to DNA damage by recruiting E4 ubiquitin-protein ligase ufd-2 to DNA repair foci. Interacts with key regulators of transcription and represses transcription. Acts as a histone-binding protein that regulates transcription.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1 25">
            <text>Thiol-dependent hydrolysis of ester, thioester, amide, peptide and isopeptide bonds formed by the C-terminal Gly of ubiquitin (a 76-residue protein attached to proteins as an intracellular targeting signal).</text>
            <dbReference type="EC" id="3.4.19.12"/>
        </reaction>
    </comment>
    <comment type="subunit">
        <text evidence="15">Forms a complex composed of deubiquitinating enzyme atx-3, adapter ubxn-5 and cdc-48.1. Forms a complex composed of deubiquitinating enzyme atx-3, E4 ubiquitin-protein ligase ufd-2 and cdc-48.1. Interacts (via RRDR motif) with cdc-48.1 (via N-terminus) and cdc-48.2 (via N-terminus); the interaction with cdc-48.1 is not required for atx-3 enzymatic activity. Interacts (via C-terminus) with ubxn-5. May interact with ned-8.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="23">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.12" evidence="4"/>
    <dbReference type="EMBL" id="JAEHOD010000036">
        <property type="protein sequence ID" value="KAG2441276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TM66"/>
    <dbReference type="OrthoDB" id="10063692at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd01767">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.287.10:FF:000018">
        <property type="entry name" value="Ataxin-3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.70.40:FF:000004">
        <property type="entry name" value="ataxin-3 homolog"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.20.90">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.10">
        <property type="entry name" value="S15/NS1, RNA-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033865">
        <property type="entry name" value="Ataxin-3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006155">
        <property type="entry name" value="Josephin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029071">
        <property type="entry name" value="Ubiquitin-like_domsf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001012">
        <property type="entry name" value="UBX_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003903">
        <property type="entry name" value="UIM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14159">
        <property type="entry name" value="ATAXIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14159:SF0">
        <property type="entry name" value="ATAXIN-3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02099">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00789">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02809">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01233">
        <property type="entry name" value="JOSEPHIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM01246">
        <property type="entry name" value="Josephin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00166">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00726">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54236">
        <property type="entry name" value="Ubiquitin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50957">
        <property type="entry name" value="JOSEPHIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50033">
        <property type="entry name" value="UBX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50330">
        <property type="entry name" value="UIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9 19" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="13" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0645">Protease</keyword>
    <keyword evidence="24" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0788">Thiol protease</keyword>
    <keyword evidence="12" id="KW-0804">Transcription</keyword>
    <keyword evidence="11" id="KW-0805">Transcription regulation</keyword>
    <keyword evidence="8" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="Josephin" evidence="22">
        <location>
            <begin position="1"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="domain" description="UBX" evidence="21">
        <location>
            <begin position="366"/>
            <end position="443"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="214"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="20">
        <location>
            <begin position="321"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="20">
        <location>
            <begin position="321"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="18">
        <location>
            <position position="14"/>
        </location>
    </feature>
    <feature type="active site" evidence="19">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="18">
        <location>
            <position position="110"/>
        </location>
    </feature>
    <feature type="active site" evidence="18 19">
        <location>
            <position position="126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000707"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022807"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00060106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00063584"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00069055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00082365"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR633865-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS50033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="22">
        <source>
            <dbReference type="PROSITE" id="PS50957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="EMBL" id="KAG2441276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="24">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="447" mass="45692" checksum="3CF67B64E9ED5696" modified="2021-09-29" version="1">MSLLYHEKQVAALCGVHTLNTLLQGPYFSEIDLAQIAHGLDALERELLGDALGNEASGNVAMDGMFSIQVLSRALESWGLTVLSLESEEARDLKAAPTSAEAFICNLQEHWFTLRRVADGEWWNFNSLFPAPQPLSTFYLTAFLDTLREEGWTIFVIRGKLPATQPGGLETLPNAGKWWSAEDARAATDEAERARKRGRVANALETALARAGEQGGSLQLRTRGTPAAAAGGNDDEDADLAAAIAASLQGGAAAGAAAGAGPGPGSQAVAAVSGGLGGSGFGAAAVGGGDAGFGHGLGEFEDEDPELAMAIAASLADQPAGAAGAGPAAGADGRPGVAAAAGGAAQPPPPEPEPLVVELPPEPEEGAEGAIELAFRLPSGGRVSRRFLASQPAACLATYLAQQLGVAPGRVAVATQFPRKELTLGADTPLSELGLTHRTMLLAESRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VQY6</accession>
    <name>A0A835VQY6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_015166</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000123">
        <property type="protein sequence ID" value="KAG2424495.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2096344at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050349">
        <property type="entry name" value="WD_LIS1/nudF_dynein_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44129">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1254"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1297"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1572"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2086"/>
            <end position="2120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="397"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="449"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="623"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="974"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1678"/>
            <end position="1706"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="39"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="401"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="449"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="645"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="986"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1678"/>
            <end position="1692"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2424495.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2181" mass="217553" checksum="9C7ACC752ED6D74F" modified="2021-09-29" version="1">MGCGASSQAAHVSAQPVAAPASGTPGSGLLGVRERSDSPAAAAVAGGLPQAPATATSTATADTGHAENATYVPPAGQVTEPDIALAQRPASPTPMGGDQEQVPVIAAVAAGASAVQLGPGPPGTSAPAVGSAVEETAAAAVGSFPSQCTSEAVSRDEDPLATVSKGVSLRGLRRLAQHIAAWFGPVRYPHATTTDVTSQWVVGVSAPHKCRVAEMRSLLPEEDVGVPLYFISHAWKNRFQDLVLAVERHLAAAGEETRVWLDIFAVNQHGDTHFQPRDVGAFKDVVRASEGGTVVIMGDVAVANPATRAWCIYEWAATLALHGPDGLHIDLDAAHRAAVVRQLDVEAAQCFKPEDKDFILGDVVAQHGSTAAFNARLKLQLALEPLGGQAAEAERLMMGPQQQQQQQQQQQQQQQQQQAHAGGGGGADDQDGGACWDWAPVQQWLTDAAAAGQAQQPVGTTAGADDDGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGSAATQCAPSRLLLVLGGPGEGKSTALAAMAATEGPLQQQQQQPGGPLQAGAGGRCVGGAAAAAAVAVHYVRYDDARSRDPVRLIKTLAFQLAARLPAVLEALLALDPADITRLGGGGGGGAAQGEHESGSGAGPIQAAAGTPDAGAAWSDEQQMQAQVEVAFQLLLQQPLMAYAAAVVAQEQPQPPRGSALPVVLVIDGVDEADPPAPAASQGSHQPPTATPWVAGNPVLRLLTAQLSRLPPGLVRLVVSSRPEAAAGQLLGSLVRAFGPVASVAAATAPAGAAAVGVPGAPAGGGAVGGVLAGVTVLSPAQLRRTSGPHAAAAAGAAGGQLQGEVVACSHVAAMCGRLGLKTPPPQLLAAQAPDAAAGSGTAVPAPPHGTTVTSLSSLHAMYDLLLAAAVMTPPPTGAVDKQGVRGDAATRATVPRLLSVLLAAQEPLTQATLQSLGLGSPQLLGMLLPGTAAGAGGNAGGRSDDLTATSTSSESSTVISHSSTSGGLFYVSEHTVRLYHRTLADYLTGSWGPGGGGRSSIAGAGVGVGAGAGVDVGLGHWLLAQHLAAPASRAAPSPYALKYTAHHLAAAVNAAAATAADAAAVPALQAAAAVAQAQLRERCGLLDEALGDWTYLAAVFRAGHGPRLVAALGALTPAALAASRLARDSLFWLRAAVHSGAAGSGPLFGLGSREERLGAGAEALARSALLTAPLGSPLTSLARRVLAGRLGGWAAAGVAPWAPPHSDWEALGLRLKGHRGEVWGLAWSPDGRQLASGGGEDGCVRVWDVNTGACVAVLHGHGAGVRSVAWSPGAGRLLASCSRDGSVRLWDSATGDTAVVLLAGDVSALAWAPLQQQDQHQHPQQQRQEQRLVLATAGFTSTPQQGVFLWDGGSGACLGLLASVTGAAAMDVAWAPPSAADANIYVGGLKVAASCSDGSVQCWDAGSGQCIWCTLGAAGAGGSGGRLCWGPVGTQLLLVSCGERVRLLDGARGTALGEMGGIAPTGSHMMQMQPDLGAAGGGDGSLALPQGAGLPRGHTASIMGMACWAAGAEVGRQGQQQEQQQVPKQQVVMVATGGLDRTVRLWELRLPRAPPAPAEGQQPEPLLAQDAGCCVAVVRGLTGYVTCVAAQPYAAAAAAAAAAGHTQHQIQQLQQQQFVFSCSDGSVQLVDAVALQAEQQQQQQQQAPDDQPASAPPSSGPAAAPAAPAVWSPDGSYIASACVGGGLAMWRLGAADSNQQCEDAQVSGCHHVISLPLTPEPLQQLPSDCNADYGAGDMWGGGGGGPASCGRVTGLDWSAAGVLVAITEAADHGSGCGVCAITGLPGAHGCSSAHAQPRVQWLELSGGCPPAPCVSCCLTHLGCGEEPASCTVLVALGGGDGLGIRLLALTPAGDSSRELGCLQLPHPRDGEGVTSSVSAEAAAPPLAMAPPPHLSDWAAPPSLGDSGAPLSAAVTRVAWCASTTATASGGGPTRLLAAAYADNQVRLWAVDPGAGSSHSQQCVQVLHQDNPMAPVACCSVSCLAVSPCGQWLATNFQPSQQQQQKSGGGQVLVWRVAAQQGGISTGHDSSPFAKSDGGPVLVLTTGVTVGNGAALALDWSPCGRWLAAGCEDRAVRVWSLSWGQGGVRPEVTAGPLVVLEGHRHSVEVVAWRRARVGGGNANVSWLLSCGADRAIRVWRHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VQY7</accession>
    <name>A0A835VQY7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_015467</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000251">
        <property type="protein sequence ID" value="KAG2422264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VQY7"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="41"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="144"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="238"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="311"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="423"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="620"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="767"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="832"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="875"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="81"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="95"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="156"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="257"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="326"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="396"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="501"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="671"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="767"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="832"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="879"/>
            <end position="894"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2422264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="894" mass="89454" checksum="D90EE0F2BA7B9ABD" modified="2021-09-29" version="1">MRRSANPLAPPQPPSPGAAAAPTVVAPSSLRGASYDQCPELLRRTLSFTQPTSSQRSPLRQPPPHLQMDPKSRHATAWSSSGGGGGGAGGGGSGSPSSAGLMPAPAAAAAAACPERHALLRSQLRAYSCSALLSCQQLQHLRTQLGPPVPDEQLPPQLPPVPLSPQPPGLPPKLSAAFASGGGPDGGIYSPGAGRSGRTLSSGTNAFCDRVLAAPTCPGAPSSPDAFGMVSSLSSAGALYDPVPGPLPPLQLGSPAGAPPPVLGPPPVGSRTGRRRSVETPSPLGRTATGDLPSPVLRMSQCASEQFAYYSSSQGGSAGCGGSRRPGGAASPGASSFNAPLSPAPPGSAPGGHVSAGRPHVMSPTYASSKHRRAPNSTLSVVGQMAERIAEERKAAAAAAPLAAASGDQMPQPSMAAVTAAVAAASARGHSRHQLHQSSDVTPGGAAASADGIPGLRCYSGLDDRSRSSLGGARSMNRGAGTSMVLRTATDTGLGTGVGATTSPGSPCRSGSSRNLRAASSPQAYVFPPATVAAAPAPATAAATAPQDALLRQRSGRSLLAAAAHEPSGSEYSTCQDEEVLGPPAEQTHVFRLTADGSASHDGSLPELDYLTILLSQDGPRRQQQPLPQPPQQRSRDNPQQHPARAPVVPRLRLPTGGGVDADARQPITNTPAAAASVAVRPTASGSGGSSCQLDGDRHRLNTLASQIVAGHDAATAAAAAAAAHLPLTRLTYSGTGRTMPVLTDVGGIHDYLDDLVPAEPQEVEVVEAAAQQQQQKRRTPQLLLTNLPPPPSPPDTERTRGFKATVANAVATVAAAALKEQLAEGARLAGAGKGSGGAGGGAGGGAGGGEGRQSRSASVQGLGFGLGGEASRLRLPESLLSKAAQKARSSSRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W051</accession>
    <name>A0A835W051_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Anaphase-promoting complex subunit 4 WD40 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_013128</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000069">
        <property type="protein sequence ID" value="KAG2432059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAEHOD010000069">
        <property type="protein sequence ID" value="KAG2432060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W051"/>
    <dbReference type="OrthoDB" id="529961at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47822">
        <property type="entry name" value="CARBOHYDRATE BINDING DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47822:SF2">
        <property type="entry name" value="F-BOX AND WD-40 DOMAIN PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="304"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="36"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="51"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2432059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="524" mass="53305" checksum="9B5D8F097B53ECA8" modified="2021-09-29" version="1">MSSQGLTVQASSRSVASKAPPPKAPADDDDDEFVDDGGRAAEEIGKTFTYRSTLSAAESAALESFRRRDRSEDDEQELNPLPAKQRNATYADIRQPVHTRALGPGAEALCIAASSSGNVLAVGGRHGTIQLLHPHTLEPMDTLLVAELGAPAAAAGAGAAAGAPAAAAGVAASGGPRANKAGGAANGAAGAAAARRGGGNSGGLTGGDGVVTSLVFRPDVAGSRMQNVLLAAQADAIVHVHVGTKRVLHVQREERNRINTLAMRADGRMFASAGSDTVVRVYDEAAAPGGAACRTLDHGDGVTTTGHTSHVFSLAWQPDDPQILLSGGWDNRVLVWDLRVHRSVRSISGPHICGDALDISPASGAGAPADTPLVLTGSWRAKNPLQLWDLGSGRLLTNLPWWQPEPDGCLPYAARFGTGAAAGLVVAGGSGVKPLVRVYKLKSPGNCDLAFTVLTNRPVHATVQVQGFAAAPTTPGRAGSAAAAHGAPEPCVAVACDNEVHLVSLSSAIHGPTTAHPHGHAGGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W060</accession>
    <name>A0A835W060_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_012393</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000058">
        <property type="protein sequence ID" value="KAG2434380.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W060"/>
    <dbReference type="OrthoDB" id="543305at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001730">
        <property type="term" value="F:2'-5'-oligoadenylate synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11258">
        <property type="entry name" value="2-5 OLIGOADENYLATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11258:SF11">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2434380.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="379" mass="43198" checksum="291C386E0DCFB130" modified="2021-09-29" version="1">MPWFDPNQEEQLAAKAALEKVTCVRPVGSWARQTAVTQGFDIDVVAFVRRFEGTDVTSLEMWRGDKLTRMRRHVKDQLQAADPSWKVEVRNDAHYQHVLHVTVGEVEVDLLLAPDCTAGGKVGKMWASTQHKRLRKPLLSNPAATVFDLVRHRSDSAALIEFYIGALADVLEVMRFVKGLYKYGVQVAPGCEHIRSLSLEVLVLAAHQRLRSTKYRRNPKGRAYKMELLVEFLRLVVAAVEKREVVMLDVSYWCRAVQPYGYSREVGMQYVHIWGNDPMIVIHPTDFTCNLERPPEGRAASDWSGLVQLAERLLARLERNDVVGFWAEPEVVRAMVHAVRLRRAIVEGDGHHRRLRQYLGGAAPVKRARKQSRVLRAVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W0T3</accession>
    <name>A0A835W0T3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013155</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000070">
        <property type="protein sequence ID" value="KAG2431936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W0T3"/>
    <dbReference type="OrthoDB" id="549504at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="22"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2431936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="170" mass="19076" checksum="5FCF666A79DDFA7A" modified="2021-09-29" version="1">MQMLMLGRSHRDVVLNASAWQDAAEDNAEGGGEGGAGVGGDEDGDDLWDSFRSVAEREKQQKEEEEKRRKELEQERERERLRAVAEARQAKEEEERKMREAEEQAAAEEKRKKDEARAKELEELQMQANTAQVYQPPDAAALGSLDPAGADINDLGLTYKHDEDGDGFED</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W1Y5</accession>
    <name>A0A835W1Y5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_011217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000046">
        <property type="protein sequence ID" value="KAG2437577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W1Y5"/>
    <dbReference type="OrthoDB" id="553132at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031937">
        <property type="entry name" value="PNISR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48134">
        <property type="entry name" value="GLYCOPROTEIN 96-92-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48134:SF2">
        <property type="entry name" value="OS04G0609100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15996">
        <property type="entry name" value="PNISR"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        </location>
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        </location>
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            <begin position="243"/>
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            <begin position="1127"/>
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        <location>
            <begin position="1148"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
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    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2437577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1164" mass="123923" checksum="2213100F719AD71B" modified="2021-09-29" version="1">MIIQQPQGMQGLPQQILLHPQNPQQQMPGMMEQQQHGIMLMQQHQAHPGHPGMQGGQFAPPQQLGSFQQPPPPPQDPAQQHLQQMQHMQQQAQQQAAEYQHQQLQQQQAQYHQQHQQYQQPQPQQPQEQQQQQQQPLTNYQKQMLAERAARGQTQQQQQPPLQQAHSGQHLQGGGGGGGMVGIVPPPPPPPPRQDPDGGGAPPPPPPPPPASSHPSNVQAAQHHLHLQQQQQQQQTHSQQQQESAPETMEQQAFDSMTAEQQAAYMEQWAAYYQQQQQYYYGGGSAAGQGAGAGAGAATGAAGQQQQGHEAYAYGQYGYGMDGQQYGYGADGYGAQAGMYGAGMMQQHHSAAAAGYGGGYPQQHAAAAAAAHQHQQMAMMGGGQHHPHMMMMGGGQAGAVAAGAHGGFMQGRLDVSGGGGMMGMMGASGMISPGAASSGAAGSGGSGRHIPEWLRQELLKRQAAAAAANAKKGSDEDEDEDDDEDGGAKKAAAAKPKRHFTEAPAGAGGGSRWGGPDKETDGGKGRGKAGARPQESEDEEDEDEEEAAIRQEVVNREIKSNLTQILLEVTDALFEEVAREVYAETAPAKKSAAEGAVKLQAGAALIAGGDDEDDEGGGGGGAGLLGLGYGSDQDDEENEQEKKEDQTAATPDAGRKASGAAAGAAAGAMATAGGNKGGAAGAGDGGAGGAGRRVESDDQQAHQAGSRRDGADVQDSQAAPTQASTAAATAATPPEPERPALYSKGQSVWLLGREGEGGTRLPAKVIAVLPPAAPGEAPRYSLVAEGRKVTAAEAQLASLEDRLQPQQPTAVPAPAAPAPPAAAPATAAQAAAAAAPPAPQPASIAAPQALAAGQAATVAAAVPLPSAAAAAPATHAEPKAAAAPAAHPGGSKPKEAPEAGAARKGAKAEEPEPRDDKARRRKASRSKSRSRSRDRRRSRSRSRSRGRTSRSRSRSRSRGRGGRRDRSRSKDRGRDRRSRSRSKDRERERARERERERERERDRSRDRHRDRDHDRWQPARSRSRSRSRSRSRDRKSRGDRSRSEREVERQSSGRERDRDRDHGRDRERRAASRSRSRERERGREKDWDRGRDEGKGRSEREKSSGKDKKDKTEKKDRDKKRRREDSASGSGSDSDSGSSRSRDEGRSRKSSKHKSKDKKSKKER</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2023-02-22" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W389</accession>
    <name>A0A835W389_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_011059</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000045">
        <property type="protein sequence ID" value="KAG2437680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W389"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2437680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="175" mass="18651" checksum="1158A58438BBD7CD" modified="2021-09-29" version="1">MEPCLDLGVWGVCVGGYYVYTPDQALTLYEVDYYSHGSLGAGEQQFNDTHLSCFNDDPNNTVFGDYITSWEGSPRDCSARARAGGFAYYGLKSGGYCVLSRNVTELAVLTPKEEADDFEDEDLEDIGLGGGEAEAIDESQLGPLPEVRHQGTAAVQVRPLWSAAAAAAAAAAATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W7E9</accession>
    <name>A0A835W7E9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Coilin tudor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009402</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
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            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
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            <taxon>Chlamydomonadales</taxon>
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        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
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                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAG2443337.1"/>
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    <dbReference type="GO" id="GO:0015030">
        <property type="term" value="C:Cajal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="F:U2 snRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:spliceosomal snRNP assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024822">
        <property type="entry name" value="Coilin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056398">
        <property type="entry name" value="Tudor_Coilin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15197:SF0">
        <property type="entry name" value="COILIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15197">
        <property type="entry name" value="COILIN P80"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23086">
        <property type="entry name" value="Tudor_Coilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Coilin tudor" evidence="2">
        <location>
            <begin position="525"/>
            <end position="592"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="100"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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    </feature>
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    </feature>
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    </feature>
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    </feature>
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        </location>
    </feature>
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        </location>
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        </location>
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        </location>
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        </location>
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        <location>
            <begin position="403"/>
            <end position="420"/>
        </location>
    </feature>
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            <begin position="421"/>
            <end position="443"/>
        </location>
    </feature>
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            <begin position="449"/>
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    </feature>
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            <begin position="697"/>
            <end position="709"/>
        </location>
    </feature>
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        <location>
            <begin position="710"/>
            <end position="740"/>
        </location>
    </feature>
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        <location>
            <begin position="756"/>
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        </location>
    </feature>
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        <location>
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            <end position="800"/>
        </location>
    </feature>
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        <location>
            <begin position="829"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF23086"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2443337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="893" mass="87705" checksum="077215E8348D7A9B" modified="2021-09-29" version="1">MMQRIRLEIAEELLPPGLKEAGVHRTWFWPSPAATCVAAFSHEVLARFQLRCPGGPAGLQLLLSGFALPPDAPIGILRDGDLLVVQRLAVAAAGALPNVAPKTARQAAPKPARIEAGAPGPSGGATAGAAGGAVAAAASGKKRKSPVVGGAEAGPAEAPTPQPVAQHGSSALEGNCAAPQPVDAATGAAEASPDAAMAEAPATGGSDKAKGPSRSARRKAAKRRLKRTGVLPYGDAAARVDAKAAPGSHQPQGGGAAGAPPAKKQRQNLQSQQQPQHAAKGQAMALTPAANATAGLLAAAMAASPLDPNGVLMQSHQPQQQQQASAQQPQARGCGSGAGPSTGGAAARPAAPQAAAGARPAQNGGAASKGKRGLRLDDSSDSSEESSGDGSASSSSSEEEEGGSSSSDESSSSSSESSSSSEEESSEDSSEESSEESSSDGEEEHARKAAASKAKAAAVTPAPVAKPAAQPAPTKRQAARGTSSGAAAAVVAPKGRPLPPPPPPPPAAPPAAAAAAASAPAVSNNNYEALPAVVGPVPVGSVLAYKLLEIGADMCPRVSPWRMGKVTSWDGAEAVVTLQPHPDARSHPLQAELDVLKARLSAEAEAELEDEEHDRGKAPSSADVELDWDSLPFPTEYQEDGTLAMPLAGFADVRAVSLPAGAQAARTAAGGAPRTAAASVPAAAASKAQPSRAAGIPPSPVNLGPPRPSPAAQVPVRGPPGGAAAVARPPPAINRAATATPGGGAKPRLPPPGAPPAGAVVAAVGGWADLAEQLRRRRQELASPGGADASSGGPPASGAAAAGGGPPLPPEVSVPAFTPKGRMPPQRQGAASIGPPAGGSDAASSAGASPATADGEGSRPSGVQTRGAVRPRGGVRRIALGPMLNHLRQSGEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W8E3</accession>
    <name>A0A835W8E3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_009950</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000035">
        <property type="protein sequence ID" value="KAG2441358.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552579at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
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    <sequence length="2277" mass="214186" checksum="CA66027F00185DEA" modified="2021-09-29" version="1">MAAKRLWCCFTGGAVEQAFKPLGEGSAQSYTRRGTEDSAAEPVEGARPPAGAASRDSSGSDAGSGAGAGAGAGGHLSPRGSSSSHSPQARLCTLPVPPTAALRAGSTLYAGPSMSGHSAWSAASSEGHHHLGPTPSRLSAASHPHPNGSLSPGPAAPLPSGAGNAHGNAITSPLLGAGRSRGGGGGGHAGAGAAAGGAGAAAQPLTSPGSTAAGNGPAPPANRSGSGVANALSGALRALKRHGTNIGSKAPSDRASLQRITGGGGAPLVSSVPPPPPGLQRSPSDIRQHLQSQTPKRSILKHSSANRTVSLSRLSRSSKSMAVRHVGESAVSFRVKVAGSGGDDAEDTATGGGHDEASDAEQPPLRRRGFTASGVSFQVAEEDGKAGGRVSSNGDGVGAAAEAGEGGAGRVGRTGCEAAGAAGGRTGPRWRGSKSVRVVVPEDDPDAQLAAVGVSAAAEAAAARAAAVAAKRNATEAGAAHDETEGEEEEEDGEAELGASAAAEAAVRRTLRSSTGGLMGRMVSPVAAGSPLTRARSIGFAATPLELFGAPRSSSTTHGTGKQQQRGRNLVNTFLTSVSGGSGPSTGAGADGSGAGEGGDGAGLGNAGPSAGPAARAASPSASMPDAVVRFRRPLSHSASTSSLNTTIDGGVATAGLSPEASAFARRSAEASGSAQPFILSSSSGGGGIADDAGFGAAASRFGPRSSIVGRGGASYRLLSVRSAIEQHRGRELERARERLGLQADGADAGSLGDSTEDGTAVSAEQPGPQAAPVLSALSAAGTAAAAERPRASAADGLMEVAAADGRPVVQGELLAEALASTEQGELLAEALASTEQGELLAEALASTSASGAGCMRSSNASSSSSSSSPASGAPRSASLSGTEWAGVRPHTGAAAAATATAAAGALLSGHTQAHSGSGGGGGGGSLARAAAALGPMHRHSDGSGGGSASGGAGGAAARRLSARPQLPLAPSPQHPSPADSQRPGSSSLHPQRRASGTGGAPCATSSGSGAGAVELDRDSAGGGGGGGGRQGSLLSVVVPGGGPDIASVSAHEEALLGLESGTGSAAPVSPFTPSGGNLIVGAPPALSSGGGSGGSGTLPGGASRRGSRTASHSHIQLPTPVSSTVLPTRGASPSPSFSARMLAAATGGRMGATVVPEPCPLSPRSGGGGGGGVSGVSGVSGGGGGDSGGGVASGPSTGPVAQATASPPILQRNRSAAGATGPMPMFAGAPQSPLPLPYMVSPLSAASTGNSLAGAAASPATSAAGCAAALAVAATAAAPSSAAAPASSAPDAVARAGNSVGGAEGAGSRVLSPRPASGMRVSGAQFVRSFSLSASEASPAPADAKAAAGGPGGGAATSRRPSGAEVAAPPSLARLASAMSSSALVPGGRGGSWGGGGGGGGSAITSPAAAHSIEGGGLRSSRPTSPANYLPLADPGAGTPGAPCNSSAHASSAVAGGGTGGGGSFVASRLGSWRQLASPLSALRAALAGGGSMGGGGSGGGASGAGSHMGSSGAVSSDCDHSSSALSPPQHQPHQHQHQYQYPQQLQRSPSSTAAAAAAAAAHDAGAAAAAAAPSSSASRLSIRVAPSPMSTQGHLQYAAAAGGGGGGGGPGSSFGSAAGAGRRPGTPTAGGSRLSVAVPLSAAEAEAGGLSAYGVTTYGAAGATEPLRPGSPAAAGGGFEQVSSPPSRMQGLGGAATSVGVAAAAAGAGGSGTGTGSGGGGGSMSRDLLARRKRGSVSGMEYANYIAARAAAAAAAAATATAAAAAGSGTAPGTGGVADAGADGGGSPPSRSGRRKNRTMSTGGSSLTGRAVYALEAMAAGLGFTRGSVPGPVPSGGGDDSVRGGGGGGGAAAAAAAAAGVGAAAPARSMRPATGTGWGSSDVVEALGGELGGPLDEFAEEGLALSPAAAPAAAPAVPASWGSPSPGVGGRSAVPAVAATHNRGPSGGVGAAAGVALAASSPAGPRPRTGSVQGAVAQPRSPRAALGPDRSARGFEVLHGGEGPDRQEGWELREEEEDVLGRLDSEGPGGARALARAPSGTAGLLAAAAIAGDGGAPATPRFGRRAAAAAAFGSGGISGSPVVSGAAPELLSPQPSFRHSPQPSSLLRRAPTLPTHASFGAGAAQGTQSVMSMAACAAALAPRYSTPGTGTTYGNLAQARLSSNGASTGATAAATAGQPPPERLRRESVRLMSDWSSFSVAAAVAAAGGGGSGGGGGTDRAPISASRMASAMAGAATQGLRRDTQDSGSDSGSMHLNVTLGQSPGLLGPLPGAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W9G5</accession>
    <name>A0A835W9G5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Translation initiation factor eIF2B subunit gamma</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">eIF2B GDP-GTP exchange factor subunit gamma</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_009990</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="8">Acts as a component of the translation initiation factor 2B (eIF2B) complex, which catalyzes the exchange of GDP for GTP on the eukaryotic initiation factor 2 (eIF2) complex gamma subunit. Its guanine nucleotide exchange factor activity is repressed when bound to eIF2 complex phosphorylated on the alpha subunit, thereby limiting the amount of methionyl-initiator methionine tRNA available to the ribosome and consequently global translation is repressed.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of the translation initiation factor 2B (eIF2B) complex which is a heterodecamer of two sets of five different subunits: alpha, beta, gamma, delta and epsilon. Subunits alpha, beta and delta comprise a regulatory subcomplex and subunits epsilon and gamma comprise a catalytic subcomplex. Within the complex, the hexameric regulatory complex resides at the center, with the two heterodimeric catalytic subcomplexes bound on opposite sides.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the eIF-2B gamma/epsilon subunits family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000035">
        <property type="protein sequence ID" value="KAG2441401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W9G5"/>
    <dbReference type="OrthoDB" id="10250549at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005851">
        <property type="term" value="C:eukaryotic translation initiation factor 2B complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002183">
        <property type="term" value="P:cytoplasmic translational initiation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd04652">
        <property type="entry name" value="LbH_eIF2B_gamma_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.160.10.10">
        <property type="entry name" value="Hexapeptide repeat proteins"/>
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        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
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    <dbReference type="InterPro" id="IPR051960">
        <property type="entry name" value="eIF2B_gamma"/>
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    <dbReference type="InterPro" id="IPR056764">
        <property type="entry name" value="LbH_EIF2B3/5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005835">
        <property type="entry name" value="NTP_transferase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45989">
        <property type="entry name" value="TRANSLATION INITIATION FACTOR EIF-2B SUBUNIT GAMMA"/>
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        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="5" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
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            <begin position="8"/>
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    </feature>
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            <dbReference type="ARBA" id="ARBA00046432"/>
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    </evidence>
    <evidence type="ECO:0000259" key="11">
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    </evidence>
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        </source>
    </evidence>
    <sequence length="513" mass="51964" checksum="F3B34EBA9677DA96" modified="2021-09-29" version="1">MVNASYQAVVLAGGEDQILYPLTTNTVKALLPVANKPLISYPLRTLAEAGLRSAIVVVIGEKAAASVREWISSEYAGSPGALASCEVVSVPEGYGTADALRAVASRITSASFVVLSGDLLTDVPVGALVAQHNLHAGAMATMLLAHRRVSPASETKPGKPPKNVDYIGLDPTRQHLLFYASSPDALRDLKVPLPTVRRYGNMSISSNFVDAHLYIFNRSVLQILSDNPKLSSLRQDMLPYLTQNQFRIIRAQQLASSAAAMAGSSSGGAGGGAGGAGGAGGEAGGAGAGAGSGGPGGAGAGGSSLLTAPSTEIETDAASDLRFNLHAELPGAHYMDMSHGAAAPPVPESLLRVQVVGPQDGYCARVQDVQMYGEVNREVADPGVALKLSGLKPGRHDNIVPASATLGNKCTVAAACILGEGCAVGDKSSIKRSVLGAGVRLGANVKVINSVLMDGVSVGDGAHVQNSVLCRGASVQAGATLKDCQVGSGCVVAGGVEYKGEVLVTKGAAAAGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WAW7</accession>
    <name>A0A835WAW7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009211</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000030">
        <property type="protein sequence ID" value="KAG2444011.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WAW7"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="222"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="102"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="103"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="427"/>
            <end position="442"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2444011.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="537" mass="55157" checksum="7FD25F75F9BD6DD1" modified="2021-09-29" version="1">MTSTFWDACPTEPAAAAAAGVAAGGSSSSARGPAGDMAAGWLELSRRSQTDGTSCGWTSCKWGGCGSGEVEVQTRWCGFAYAELCCRSRTAVTCARVLACTPAPSPPSPPPPPIPAGAPAPPSPPPRPPPSPSPPPPPRLLQPGGRLSLLARTPRAGPLSVWFAMHLCEMSYIKNEREGQEAWEARVRSHVVGELGAADVKFFSGRRAGGDAYLVATRDLVVLVFRGTDTAADDGDQVANIAAQLGSDVDTSFFGGGRVQVSAAYLNAYRELQEQEGLLRAVAQARGSPARPLWVAGHSLGGVMALYAAAALANAGSSVQAVFAFGALNSGETDWVRRYSALGLDGVTSIVRLSGDRLVELPVGHRQVNGAYLYLDRDGCPFSVSSSSSGSNITGAGRRRLRMGSTPRQIVGGLGGAAASRRRRLQQELQPSASSVPAAGAPVAPAASGIASPLQALGGGDSSGKAGAPFLQQAATATATATATTATAAASGTDARNALVDVLRPLGGTHGTRYYLQALAGCFPLDDPLQSLFRQHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WB68</accession>
    <name>A0A835WB68_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009114</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000029">
        <property type="protein sequence ID" value="KAG2444176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="545626at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="35"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="93"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="298"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="967"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1399"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1452"/>
            <end position="1480"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1541"/>
            <end position="1583"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1399"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1541"/>
            <end position="1559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1566"/>
            <end position="1583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2444176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1774" mass="178862" checksum="701CEAB97C673CF1" modified="2021-09-29" version="1">MLRRRWPARTGQVAGEDEDDASLLKPLKQRPRPSLRVLVTTLVNAVWSSILPPADVASSEYSEYLTERVKGLTIGWHIFRTVTEGAFLASYGLAFNTVVVQIFWMISVSSVVLHFAKHKWWLAIREWLCVNTNRMYGVITVLKIFHLVPRLPNENNYMFKHCFLTMADAAFAQTPVHRQYLVQFAEAAIRCVVWRRYHVLPNVPTWGVICISFAWQIWLVTFASMLQARHVSAFRRQRRASRDGAPADANTVAAAAGPSTSAAPPSYSITAEAAAAAAPMPAPAGAVEVGEGKEVAEHAAAARSAAPSVSSMTATSATGSGVTSGPTSRAAAPSRRSAGSRLGPSGGSSSAAADAGQPQHQQPSLSQAQQRYMTALRCVARGPSSYVLLSHQRRQAGANPCATAQFYIPAASPEQLPANWRERLAVAVAENAPGWQLASACVRTGSLIVHLDLVYVPPAPAHGPRSTAAAAAGAAAVKRAAAAASADTAAAAAAAAAADDAASAVLSPFTAVSAAYTASPFVAAAAKVAPGSSAVNSGVTDDSSSSRDVLDGYLSGMSAESLMELLGLAPEDGGAEQQPVAGADARPVSLQIGDSMCYLASSSAATSAAATTSRVSGSGAGAVATTAAVLLQPALAPPIADEPAAQPVVAAPAAAAAAATQAPQRRPLKSFLSEAVRTALAPPAELRSREYAAFLSARVGQLHLAYAGFMCFTAAAFCVLRAANGVRPLTLVLFLGAEVLTLAAHGLGGGRAWRAARCGLVYAGVALRSVQMLACTVGFLPHMLRDTDCVTGRWVQKVLLVTTLQALCMQPPVRTFFAVRLPSVLMAMHVHVVVCQAGLSAAAGAALHLGWEAVMFVICAGLQLRHLEAFRCQRITAGASGAVAAGAGISSLAAADTAAAADSCGAAGLAGKSTGTGLGSDNSNGQLPAALSPLMSGLDSAMGTDQTPAAAVAKEKAQALAKLGPGPEAAAGAAASRPTSASGAAPAASPLAPCAASGDPTAVSLSAAVVALAPRRAARLQLQFTCTPAVLDELHVVLRHVSPASMATGVHAAHAARDITHALAAPIAAAGAAAALPAEWSAELTLVAAAADVPGVVHVEIWRGRRRVVSNPVLLVAAPQRTAAVTAMDLLRANGDRAMDDSAGAASTLCGGACASGSCSSSSGAAGRDGCWVDDITAYVSGLEAEGHGAAAAQFIEELGSYLAQVAAVERGLAGATASGGAGAGAAVANVLYFHGLTSDFMYLKPRAADGSAGGSSTSGRGSAKAAAAAGAVDPTFRQLLLCQGSMLLAVAAEAGCTALSAHLLQLMTGPLAADAAAVLDAARTPVTQLPLLHAAVKSGRPDMVDLVAQWSAGVGLADIWAQEAAVLAVTLSDAADSSGFLPSGSVSRRASLSAGSSGARRSLNLAGGPAAGAPRLGRSPSYRSSQLARSSARDVELRIHEREVAAPVTVTTGATQQQLPRSARGSGSFSTTAHAGGNGVSGEVAADAVVADDGAAMVQDLLASCSNALNNADGETPFRIIAFRGSGRAVAAAPAAAVNGDDGAAATPAADQQQQQPEGVRDQRQQQQQQQEAPRTSLDGGPLVDGGVVVLTPLHLALALGDNGALASHILRTYPEAAELLRVGMGVAVGLDDDAATGASASACGITVSGRGHASALDSSGAFAGGVSSSAAGVAAEGECGNSTAAALAAAAAGGPHLMHAFNSMPGLGRGGAGGAAITYLAGGAAGDCSDRDSMDCNSMQSMSLSEVAFLEGMRWVNQEEAPRRPGFKVTKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WGB3</accession>
    <name>A0A835WGB3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446719.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WGB3"/>
    <dbReference type="OrthoDB" id="546586at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="586"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="225"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="417"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="448"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="469"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="517"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="545"/>
            <end position="554"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2446719.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="586" mass="57438" checksum="B937DA499454AE7E" modified="2021-09-29" version="1">MPLVPHTLLFGCYFDWANSVGEFTTSTERSNAIRVIDGMTYEGAKLRCEPLHMEDGPDAVEERGAPAASDRYDGGAPDRTGGGGGGGSYHKSERAAGGGHEEKSYPREERRAAGGEKAAAAGGGYDDRYGYDEPYEGGGGGGGGYSSREGGRAAAGYEGGGGRAVPAAGGGGAAYDDRYPPEKYSRGEYPPTSGRGGYEGGGGRGAGYYEGGGGGGGYREPAYREGGGGGRGGGGGGGGYEGGRGGYEGGRAGYEGGRGGYEGGRAGYEGGRGGGYEGGRGGYEGGRGGYEGGRGGYEGGYSSREAGYSSREGYGPAGGGGYREPARDADYGPSGGRGGAGYDERYPPAKYARTEYPPAAGGGGRGGDYWDGYEGGGRGGGGGGYEGGYEGRGGRGEPGYGPPPAKGDGYAAGPPSRSERGADYGRGDGYAAGGYPAREAGYGGSARGSGAAAAGGSTRDAGYYERGYEGGGGRGGGGGGYERGYDRGYDRGYDRGGDYYDEPGYKSGGGGGGGYGAPASRAPPAAGGAPAAAAAAPTGSGGRGAAAAYPADAGYEGSGRGGPDRSYPPARSGGGGGGGYERSAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WHB3</accession>
    <name>A0A835WHB3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1</fullName>
        </recommendedName>
        <domain>
            <recommendedName>
                <fullName evidence="10">Methylthioribulose-1-phosphate dehydratase</fullName>
                <shortName evidence="10">MTRu-1-P dehydratase</shortName>
                <ecNumber evidence="10">4.2.1.109</ecNumber>
            </recommendedName>
        </domain>
        <domain>
            <recommendedName>
                <fullName evidence="10">Enolase-phosphatase E1</fullName>
                <ecNumber evidence="10">3.1.3.77</ecNumber>
            </recommendedName>
            <alternativeName>
                <fullName evidence="10">2,3-diketo-5-methylthio-1-phosphopentane phosphatase</fullName>
            </alternativeName>
        </domain>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_007912</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-(methylsulfanyl)-D-ribulose 1-phosphate = 5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O</text>
            <dbReference type="Rhea" id="RHEA:15549"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:58548"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="4.2.1.109"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>5-methylsulfanyl-2,3-dioxopentyl phosphate + H2O = 1,2-dihydroxy-5-(methylsulfanyl)pent-1-en-3-one + phosphate</text>
            <dbReference type="Rhea" id="RHEA:21700"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:49252"/>
            <dbReference type="ChEBI" id="CHEBI:58828"/>
            <dbReference type="EC" id="3.1.3.77"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <text evidence="10">Binds 1 Mg(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="10">Binds 1 zinc ion per subunit.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 2/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 3/6.</text>
    </comment>
    <comment type="pathway">
        <text evidence="10">Amino-acid biosynthesis; L-methionine biosynthesis via salvage pathway; L-methionine from S-methyl-5-thio-alpha-D-ribose 1-phosphate: step 4/6.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the C-terminal section; belongs to the HAD-like hydrolase superfamily. MasA/MtnC family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="10">In the N-terminal section; belongs to the aldolase class II family. MtnB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.2.1.109" evidence="10"/>
    <dbReference type="EC" id="3.1.3.77" evidence="10"/>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WHB3"/>
    <dbReference type="OrthoDB" id="191080at2759"/>
    <dbReference type="UniPathway" id="UPA00904">
        <property type="reaction ID" value="UER00875"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043874">
        <property type="term" value="F:acireductone synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046570">
        <property type="term" value="F:methylthioribulose 1-phosphate dehydratase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01629">
        <property type="entry name" value="HAD_EP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.225.10:FF:000010">
        <property type="entry name" value="Probable bifunctional methylthioribulose-1-phosphate dehydratase/enolase-phosphatase E1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.720.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.225.10">
        <property type="entry name" value="Class II aldolase/adducin N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03116">
        <property type="entry name" value="Salvage_MtnB_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_03118">
        <property type="entry name" value="Salvage_MtnBC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001303">
        <property type="entry name" value="Aldolase_II/adducin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036409">
        <property type="entry name" value="Aldolase_II/adducin_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023943">
        <property type="entry name" value="Enolase-ppase_E1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017714">
        <property type="entry name" value="MethylthioRu-1-P_deHdtase_MtnB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027505">
        <property type="entry name" value="MtnB_viridiplantae"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027514">
        <property type="entry name" value="Salvage_MtnB_euk"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01691">
        <property type="entry name" value="enolase-ppase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03328">
        <property type="entry name" value="salvage_mtnB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10640:SF7">
        <property type="entry name" value="METHYLTHIORIBULOSE-1-PHOSPHATE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00596">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00702">
        <property type="entry name" value="Hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01133">
        <property type="entry name" value="C1.5.4:_Enolase-phosphatase_Li"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG01129">
        <property type="entry name" value="C1.5:_HAD__Beta-PGM__Phosphata"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00044">
        <property type="entry name" value="enolase-phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01007">
        <property type="entry name" value="Aldolase_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53639">
        <property type="entry name" value="AraD/HMP-PK domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 10" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="1" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 10" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8 10" id="KW-0456">Lyase</keyword>
    <keyword evidence="6 10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 10" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="9 10" id="KW-0511">Multifunctional enzyme</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Class II aldolase/adducin N-terminal" evidence="12">
        <location>
            <begin position="13"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Methylthioribulose-1-phosphate dehydratase" evidence="10">
        <location>
            <begin position="1"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="225"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="region of interest" description="Enolase-phosphatase E1" evidence="10">
        <location>
            <begin position="264"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor; for methylthioribulose-1-phosphate dehydratase activity" evidence="10">
        <location>
            <position position="131"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>substrate</name>
            <label>1</label>
            <note>for methylthioribulose-1-phosphate dehydratase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="106"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="108"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="181"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="269"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="402"/>
            <end position="403"/>
        </location>
        <ligand>
            <name>substrate</name>
            <label>2</label>
            <note>for enolase-phosphatase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="436"/>
        </location>
        <ligand>
            <name>substrate</name>
            <label>2</label>
            <note>for enolase-phosphatase activity</note>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="462"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM01007"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2447166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="506" mass="53886" checksum="ED9465F27464492A" modified="2021-09-29" version="1">MSSNGISVDEAKTLICELCRLFYDQGWVSGTGGGISVKAGNEIVMAPSGVQKERMQPDDMFVLDAKGDVIHTPAVKPPPARPPKLSECSPLFMAAYELRGAGAVIHSHSMNAVLATMLDPGASEFVITHVEMIKGIEGHGFYGKCVVPVIENTARECELTDRLRQAIADYPQANAVLVRRHGVYVWGKDWIQAKTQAECYDYLFEAAVKMHGMGLDYRRPPPPIFADNGASKANGNGAEANGSHAAEPAAKKAKTRHAALPAAVVLDIEGTVAPISYVADVMFPYAQQHCRSFLESTYDSDETQADIALIRTQATADVAEGRDGAAAVPEPGAGKAEVVDAAVAWVSGAIAADRKVGALKNLQGHIWRSGFSSGALQAELFRDVPDALVEWRAAGLKAYVYSSGSREAQRLFFGYSKVGDLRPYLCGFFDTTSGPKTEAASYNNIALSLGVDSPSDILFATDVLAEAQAAAAAGWRAVLVARPGNKPLPEGAGGFRVITNMQELLQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WHC5</accession>
    <name>A0A835WHC5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">6-phosphofructo-2-kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_007783</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000022">
        <property type="protein sequence ID" value="KAG2447460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WHC5"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07067">
        <property type="entry name" value="HP_PGM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1240:FF:000006">
        <property type="entry name" value="6-phosphofructo-2-kinase/fructose-2, 6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013078">
        <property type="entry name" value="His_Pase_superF_clade-1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001345">
        <property type="entry name" value="PG/BPGM_mutase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00300">
        <property type="entry name" value="His_Phos_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00855">
        <property type="entry name" value="PGAM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00175">
        <property type="entry name" value="PG_MUTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="252"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="252"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="active site" description="Tele-phosphohistidine intermediate" evidence="1">
        <location>
            <position position="26"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="1">
        <location>
            <position position="101"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <begin position="25"/>
            <end position="32"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="81"/>
        </location>
        <ligand>
            <name>substrate</name>
        </ligand>
    </feature>
    <feature type="site" description="Transition state stabilizer" evidence="3">
        <location>
            <position position="167"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR613078-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2447460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="311" mass="33032" checksum="6FC60CC2D3554BA1" modified="2021-09-29" version="1">MASNSLTAEVARPGLTSVRKIFLTRHGESQYNQKGLIGGNSSLSERGEKYSRALPGALLERLSVSQDEPLSVAVWTSTLKRTIETARFLPFPKLRWKALDEINAGICDGMTYEGIAEKYPDEAAARKRDKLRYRYPAGESYMDVIQRVEPVIIELERERETVVVVAHQAVLRAVYAYFMNVPPEDIPRLAMPLHTLIELTPMPDGTMSEQRFPVDIDAVPPAPAAELTAELTSGGSGVELVAVLPEASAAPSTALPAASGSPRSSVHSSSASAAAQDCAAGSDACLPLVPASPAPSPAGDAETVATPPAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WHE0</accession>
    <name>A0A835WHE0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_007952</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447211.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WHE0"/>
    <dbReference type="OrthoDB" id="2866996at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF100">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="158"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="305"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="305"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03372"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2447211.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="355" mass="36586" checksum="C27DFE0F63FCCC50" modified="2021-09-29" version="1">MQECDEAFFGAELAAWMAKAGMKGSFVPRPVGPVPGPTEGIAVLWRAEALELVAAPRNLLFSELGPQVAGLPAEVAGTQPWLKLRELGEGAVMALLRHRDSGRLLVFSCTHAFWNPVFPDVKALQVALLCGELAAFSKQAAAEQGGGGGGGGEATAPAPVPVPVVLCGDFNSLAEKRQPDVFDPQVPEGARQVSGVYQLLSGGTLAPDHPDHPHTRVWKPGPMAPTVIPAGGEGAPRFPALPLSASGLRLGSLNALAFGREPPLTTRTATFAGTLDYVWLSQPGLEVTAALSLPFEDGGSPPLMAPGAAAAGPGAAASTQPGTWRDPVADVAMVPVPNEEYGSDHLAVGGEVQFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WIE3</accession>
    <name>A0A835WIE3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007343</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000020">
        <property type="protein sequence ID" value="KAG2447888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WIE3"/>
    <dbReference type="OrthoDB" id="539768at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="275"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="281"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2447888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="302" mass="31310" checksum="408E48AD6E3D5256" modified="2021-09-29" version="1">MAWDLHKFIFDLKNLSDSEKELCFAKLDKEGFSDPTKCQVFFALSEAHLASVGIEKLGTRLALQLAIAGGPPPLLPARTATGGAAASLGMGSSSAAAVVDPRAGSAPGADLSEDVFPSSVFCVTFTLYNGGHLVTTLTSHAQALGLRGKVRTISPSRSDFTLMASAATENHEQSLQTLRRFLAYMGTLVRLRKPAAEAGAAEAGAAEAGAAEAGAAEAGAAEARAGTSTADEAVTYVEFTSDLKAPYTSDQTLLDLYHGGQLSVSGRPATWLAAEREAQVAGQQEQSRKSSLGKSGESSVQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WKH0</accession>
    <name>A0A835WKH0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Ankyrin repeat domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_005509</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449354.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WKH0"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030149">
        <property type="term" value="P:sphingolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393:SF6">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140860">
        <property type="entry name" value="Pseudo ankyrin repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="277"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="420"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="284"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2449354.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="809" mass="79912" checksum="18E3B4210A765AC5" modified="2021-09-29" version="1">MEPAPPAEYEAHWGAPGALRSVNRADQARLVSLTAASGVLPNLQLALRVTGVQLRPRPGVGAAVAEAAIARGHLHLLRWMVGCEAGGGGAGGDGGGGYGPAAAACVRCRSALVAAAAAGQLAVLRWLHEELRAGPLTDYMLDVAARGTCGSEIKRDVAAGGGGCDNNGSCKGSSSSSSNGNTDVVRYLLARGCPVHLPTALYGAACGGQVGALRLLLRRVVLVTSPGEAAVVAARAGAGAGAGAAAGATVEAEAADASRPVLLEQVRRGVWKVVGPAPPPAPPASSSAAAATSPPGASLTAATVAPGAQQAQPAPQSVGAVRIHGSVQSRTFLCHVANGCPLAVLRRLHRQWVEPPPLAAAGAAAGVAAGAAAGVAAGAAAGAAAGAAAGAAAGAGAGAGATGGVRGGGDVVGTSVGTAAASADSCLEGWEEEQQQLEKELELDRLRRAAAAAAGAATAEAAPAGSRQRLLRQPEPGLLQPGDSSSGGGDPSCLMYEEGYPALNRVAEAAAGSLTADWAAKLDWLVSAWHYPLTDGTTAAIVDVMLRCRGDDRAALARLAWLHARGCPPPDMQAVRNAVRLGLSRTLRFCLAALPNAAPDGGSAIGRPGGGGGGGGCTEGAGGAAVGGGVAVHKPLRSLKNTEVRSACIEAARAGHVECLQALAAAGLQPSAMDPTAVLLAAVGYGQLEVAKWLVDEYGPAIEAERLAAAAGGSAGGGGGSSKRVVWLTDNIAARAAYNYSSGHRGGVEVLEWLWSRGCRFGRRALRLAAKYASEEVCDWLRRHAGRGCGGGAGGAGGVCVGDSLKARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WKJ6</accession>
    <name>A0A835WKJ6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_005709</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2448954.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WKJ6"/>
    <dbReference type="OrthoDB" id="10259977at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.4.10">
        <property type="entry name" value="Hepatocyte Growth Factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056508">
        <property type="entry name" value="HPAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485:SF4">
        <property type="entry name" value="HYDROXYPROLINE O-ARABINOSYLTRANSFERASE RDN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="HPAT"/>
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    </dbReference>
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        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Apple" evidence="8">
        <location>
            <begin position="118"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="domain" description="Hydroxyproline O-arabinosyltransferase-like" evidence="9">
        <location>
            <begin position="223"/>
            <end position="531"/>
        </location>
    </feature>
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            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF14295"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF23452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2448954.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="562" mass="62588" checksum="AADD32577FA7B090" modified="2021-09-29" version="1">MASSTRVVIVAVAFTVIATFYSLSELHRMSAMHADAETTKFATHTGDNNRILRAGGQNSAISTSNSVGTGQVGSTASVGTTATTTAAASTAVSAATTTTASTTTMGSGAHKCYTYEHTELWGDVVVWGTLNKKKTAGECCDACLTYQPTGPDEPGCNVWVYCGDEVKCGSQHQQCWLKHLVHPEASKPARVGPQTPWTSGTIDVDINADPGTDTKSVGAPRMFHTVTSAQGAAVHWQVRIHYYWWKKRKEECQKAGNCEMGGFTRLLHSGQSDDLMDELPTVVVDPLPQSMVEHSWYVVLNRPYAFVQWTQRVKIPEQYVLMSEPDHIYLRPMPNFMKGNAPAAFPFFYIEPSKAENVHITKKFTGEITQKQLEEIAPIGNSPTFMTFEDMKKVMPTWMNVSIAVFKDQEANSVWGWVQEMYGFTIALWLNGIKHVDLFLNMQAQPPWDQEMQMANGKPFYILHYTYGMDYKLSGEFTPGKFGEWRFDKRTYGSRPPPRHLGEPPKNMKNDLVRALINSINEASAALPCWDQYAETGKAVYDCEEMKTLTDPRFKKDGKAIA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WKJ9</accession>
    <name>A0A835WKJ9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005548</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449399.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552700at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039191">
        <property type="entry name" value="Nopp140-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23216:SF1">
        <property type="entry name" value="NUCLEOLAR AND COILED-BODY PHOSPHOPROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="135"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="362"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="378"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="505"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="578"/>
            <end position="859"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1003"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1076"/>
            <end position="1110"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1236"/>
            <end position="1301"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1328"/>
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    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="310"/>
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    </feature>
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            <end position="1104"/>
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    </feature>
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            <begin position="1263"/>
            <end position="1283"/>
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    </feature>
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            <end position="1299"/>
        </location>
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            <begin position="1348"/>
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    </feature>
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            <begin position="1463"/>
            <end position="1472"/>
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        <location>
            <begin position="1489"/>
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        <location>
            <begin position="1666"/>
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        </location>
    </feature>
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        <location>
            <begin position="1706"/>
            <end position="1717"/>
        </location>
    </feature>
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            <begin position="1718"/>
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        <location>
            <begin position="1959"/>
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        </location>
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    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="2094"/>
            <end position="2105"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2106"/>
            <end position="2122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2133"/>
            <end position="2149"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2150"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2186"/>
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        <location>
            <begin position="2218"/>
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    <feature type="compositionally biased region" description="Gly residues" evidence="1">
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            <begin position="2281"/>
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    <feature type="compositionally biased region" description="Gly residues" evidence="1">
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            <begin position="2425"/>
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            <begin position="2462"/>
            <end position="2472"/>
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    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449399.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2472" mass="231192" checksum="57337141C23C5A32" modified="2021-09-29" version="1">MRHSDSGIFGPLLASEDNEATEAGDAIVAARDAAASGDPGADDAVTVVVWLDPAGPRAWAHRRSLLHSAHARQQSGSGSASHGGSGACTRAGRRLWAASREGRAAAAAPREVVALHSAASESLAAYLLQRAGSSAGNGSNGSSSCSSGGGGGGGALECSDRTGPWRLWGAANSRPWRLAAAAGGSSSHGWAAAARHGAAGARAYNSSSSSGSGSSQAGSGAPQAAASAAAVQQAQPPSQNVVTPIPAPLPAAAAVPGSAAAASGQPLQPLQPLSVPALAIGDVFLSCNTVAGLEHADDWDLASLGSGLLGAPQQQPPGAAAPAVAAAGGTAGSSSSSSSSSGKGKSGNAGGSSKGDAGGGGGAAAAAAAAAAADADAAPASSSSSSSPSSSSSSSSSHPPPPQPAPPSGPRPAVAPLDPAAELLLRMSAPVGGRRLLFTSKEGAELVRRAMILARYDEIMEERRASGGAAATSAPGSGTSAAASPASVVPAAAAPSKAAAAAAGSEAAAKTSARRRPQGGASTDSGDGEEAGSSEGGGGGGGEGGGGGWLQQLVSPAANVVAALAMGEFPTPHNLARVAAAAAAAEAAEAAAEDSEPGKGGDEGGAAAGKDKGAGGSGPAAAGTASASSSSPAAAAAAPPASGGEESQKDGSSSSSNKGGPAGAASSSSSSGSSGASPVVKAPGVKPWTAAGPGAGGDDGAGSGSSSSSANPDGGSPAAASSNTDISSGNNGAGSSTIGSSRNGSGGSGSGAGAGAGSGSDKGLAGAVRGGLEAMGRGLGSMMGWGPGPDGEGATQPRPQLPAAPLTHAMQLPSVAPPPSGPRQPQSVPSGAAGGSGAGGGGGGGGKRPAGGLSAAQRAALSSDALIAELRRMEEERVIRDAEAIIATMKGDTHGGGGKGERGERSAGSSTSGATATSSSSSSSSGIGTSSGTSSSSSSGSSSTDGYLPAFSFSSYVARLPLESALRCLLATGSSSNAPTAATAATAATAATAGTAATAPSSAAAAAGTDGRTAAQQQQQQPTARRFVLVPDAADEEAAEEAAALGLAMSDAMAAAAAAEAAAAATLAAAAAAGKRAAQRRRTGSVRSGGNVDGDGDEEEDPGAADEAAAAAAAAEAAVGVRATRMEPRVALNVYDSSLRHWALDVVDAGPAPAAVPLSSRAAAAAAAAAQAAAAAAAQAAGATAAEAGGAGAGAEGTGVEAAATGGAAGAGPGAAATAEAAAALAAARASFARATSDSTANSRSSSSSTAEGNGLQGGGKAGAQALQGPQPSQSQSQSDRPAPAGPAPAGPGPAPGPGPWLALELQRLMLGAPRGPAESMGPALGIASAATSSSEEAEDEDDDHHTSSPLTTTTTTTTTTTATRATTTAAGHGLDGAAHARTPAFLVPGLTLSVRAADGTVLRLRPAFLSLQQLAAAARLAGDLAVLSWRRRRAAARWKVVAALDVLSVHTAGFPILRLPGAAAGSSSSSSGGSGGRQGPSASQQGDPGQGQGQGQGQQGDEDSDDGLPEAKELLREMGAAPQGRRSQAGSGYGAAEPPPPSGPLRLLASVGVGVLSFAGWAVASGADLADEWWSRTPWGLEEIGVPQHVSVRPVFLEDHVAELAAANGPALAAAAARRAAAAEAAARAQERRRKHPHKSEASKAAAAAAAAGAAPAAAAADAAAATAQQQQQQQQQSSQGAVPHLPALPGQQSGQQEAPAAIASTASQPQLQPNDVSPSSPASGSSSGAPAPAAGSATATPVPSSTASHARSKKRAATSGSAAATAAASYGVPGGAPGGIVLQPETLAGLSGLLNFSWVLVRAAQSAVRRVEAADGDILFGTDLAASGGGGGVTDLGFGGMGGGGAGGGLMAPGEDALMRRLGFGGGGGGGAGGFGGRLGYGASALGGGGGGGGGITSMTASQEGEIGLVARLDVRPVPAAAAVGSAAAAAATRIASAAAAATAAAARSAASAPSTAAAADNAGPDQAPKGGAAAASSDPSQQQQQQQQQQQQGSPAAADAAGTPAAGDATAQPTTSNGNGSGSTGAAAASTGAGGAGGIAIRDLGPVGPGASNRFVLTQSGNRMAGQVTRHCRFEVGLHLHLRKLLGGGGDSGGGGAAGDGLGTSTSTSSSPLLPLDAPEPVLERQQPAGPSPVGPAAAPAPPPAPRAAAAAAPSAGGATAGAATAAGDPAAGAQPLPPAPAPSAAGRGSSGDAGSASTATGAAAAAAAPAAAPPRSDAAAGTASPATSAAAASSSPSPSSSSTAATSSSVAAPAIPRLTAPPQRRPAAAAAAAQAGRNGGDGGGVPGPDAHGLLLIGDLGLDADAAALEAAAAMPSAVPYRPYRPPPMGYVDLAGLLGPEAAAAAAVEAAAKAKSAAEMSTAATAAAVAAFGAGAGAAALASAAALYGGGGMEGVMEALGREEGEEDDSSEERSSTDDSEGGGGDGGGAPGGWAASGRQAGGGTAGAGGGKTWAARGSGRGGWGRWGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WKL0</accession>
    <name>A0A835WKL0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_005888</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2449141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WKL0"/>
    <dbReference type="OrthoDB" id="544367at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="186"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="92"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="53"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2449141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="211" mass="23173" checksum="F953F02814352924" modified="2021-09-29" version="1">MATNAEKLQLAESDLRKLDDEIAKNAEDRRQLLQVILSREKVKEDCEHLWQQMASLEVDRDNLQTDKKEKKLAVEHLKQTLAAEAADGAPSTIAAVPDADGPRDQQAAAHSSPAPLRGFGGYSLVLFHQQLRAFKANPICKAFVELPAWSRLYACSAQLGASPLLLLMHALTAVVRSWLGGIALQVAVFLATAAVEWLIMWLLFAVAQLLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WMM2</accession>
    <name>A0A835WMM2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">MRH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_005257</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449731.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WMM2"/>
    <dbReference type="OrthoDB" id="28322at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017177">
        <property type="term" value="C:glucosidase II complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006491">
        <property type="term" value="P:N-glycan processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.130.10">
        <property type="entry name" value="Mannose-6-phosphate receptor binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039794">
        <property type="entry name" value="Gtb1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009011">
        <property type="entry name" value="Man6P_isomerase_rcpt-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044865">
        <property type="entry name" value="MRH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036607">
        <property type="entry name" value="PRKCSH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12630:SF1">
        <property type="entry name" value="GLUCOSIDASE 2 SUBUNIT BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12630">
        <property type="entry name" value="N-LINKED OLIGOSACCHARIDE PROCESSING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13015">
        <property type="entry name" value="PRKCSH_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50911">
        <property type="entry name" value="Mannose 6-phosphate receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51914">
        <property type="entry name" value="MRH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="MRH" evidence="4">
        <location>
            <begin position="207"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="24"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="118"/>
            <end position="144"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2449731.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="332" mass="36892" checksum="69E45F84B2911077" modified="2021-09-29" version="1">MRKVATVNQDYAAAQAEVERLKADVSRLEAEEAAQRAAEEAQRAADQAAQEQAAAAAAGSEHQELNTGADGHAERELKEEGQQATEEREETPEERGRRIASQWTNDPEAAGVPGSQEHVNDGEEHEQEHHGDYSHHEQHDHEEYNGEGGEYQEPRPDASTPLGEVRAKLYDAEGTLREAERDKQRIATYLYGNLDFGPEDVFLGLADQCFTSSQTRWTYEACIFKQAVQREGYSNSVTVGRWAGFTADYKTMLFTGGDECWNVGPRSFTVHMSCGLENRLSDGEEPATCAYSAKFTSPALCNDEELIALRNQLATLEAFEREVAEKIAKDEL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WN17</accession>
    <name>A0A835WN17_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_000326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000012">
        <property type="protein sequence ID" value="KAG2450228.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WN17"/>
    <dbReference type="OrthoDB" id="545609at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2450228.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="131" mass="13796" checksum="B047B5F7920E0E4C" modified="2021-09-29" version="1">MRATSAQVAACRAALALYRERMEVVMAERGRLTERLADSMAALGLEQEAEGGGRGRLLSTQQLERTSVEAAAAAAELDANVAAEGRATKIAKDLLSSDMFTALQCARGSMASYPYFPDALAIITEVAKLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WNP4</accession>
    <name>A0A835WNP4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_003776</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451169.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WNP4"/>
    <dbReference type="OrthoDB" id="540163at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46732">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE LA (LON) DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46732:SF5">
        <property type="entry name" value="ATP-DEPENDENT PROTEASE LA (LON) DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="159"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="239"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="247"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="265"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="296"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2451169.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="410" mass="41068" checksum="CD47B8D328C9C677" modified="2021-09-29" version="1">MLLLEELLSSPHQMLVHSAVEASHKVAARDRLGGFEAGGFSFFLSTIVKVIDVKQTETGVLLRVQAEGRVAVKSLVQAQPYFRAVVVPLTDSVDLDTLQAPTWRDICGNVERLRSLMRDVQNLSNKFKGPETSNLQRAMQWVDNPQPLVFSSSSLMLNSRPASGAPPDGLRTPPTGSFASGSYDSDDFQPSKILANQIQPDVDPIFTESISGSVSDSESDAQYAAAASTGAAGATAAASGAASTSGSGSGSGGSGSGSGSGSGTSGPAAGLPGAAAGSRGGSGGGGTSGSGSGGGGGGAGGLGFSTSSGLAAAAVLGDGSALGPGGVIRSRPSLLDLERACRLSMAAIQVLPRTTEEERAAVRAAQTAALETQDVLERLHLANKVMGEARGLLSAKCALLTLSASSSSSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WNS1</accession>
    <name>A0A835WNS1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_004794</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450286.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WNS1"/>
    <dbReference type="OrthoDB" id="1875050at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038934">
        <property type="entry name" value="At5g64816-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35548">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35548:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2450286.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="115" mass="11985" checksum="D4B10CD2FB55C0EF" modified="2021-09-29" version="1">MASNKLGGQAFSQPAPDDDWAVSDKFCCERVCVTDKLVGKVGGPAKDATKGNCVTVCGVSAQDACTDACARAVCVSASHVPAWNDACIRRCNAECLRTKQQQGAAAPVPPTQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WPV3</accession>
    <name>A0A835WPV3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">PH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_003648</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">May be involved in the transport of sterols.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the OSBP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WPV3"/>
    <dbReference type="OrthoDB" id="1914979at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032934">
        <property type="term" value="F:sterol binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0120009">
        <property type="term" value="P:intermembrane lipid transfer"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00821">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.160.120:FF:000001">
        <property type="entry name" value="Oxysterol-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.160.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.3490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037239">
        <property type="entry name" value="OSBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000648">
        <property type="entry name" value="Oxysterol-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018494">
        <property type="entry name" value="Oxysterol-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001849">
        <property type="entry name" value="PH_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972:SF205">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10972">
        <property type="entry name" value="OXYSTEROL-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01237">
        <property type="entry name" value="Oxysterol_BP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00233">
        <property type="entry name" value="PH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF144000">
        <property type="entry name" value="Oxysterol-binding protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01013">
        <property type="entry name" value="OSBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50003">
        <property type="entry name" value="PH_DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0445">Lipid transport</keyword>
    <keyword evidence="6" id="KW-0446">Lipid-binding</keyword>
    <keyword evidence="4" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="PH" evidence="9">
        <location>
            <begin position="268"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="39"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="174"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="472"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="677"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="749"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="72"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="94"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="184"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="490"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="697"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="778"/>
            <end position="794"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003361"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023055"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023121"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003844"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50003"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2451873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1227" mass="128512" checksum="A7A37C47D23F2A6A" modified="2021-09-29" version="1">MPLHKADTAHLVSATGPSAAAAAGRFSTGGMNSGNAGLAASGGSASGVPNMGKRSEGSALAAGQGHSHSDAHNSGGSAHGGSAFTAGAAGPNVNARSSDSGNHLVSGGSASGAPGSPPPPSGLHIKGTTASGHPAAPTSTQSTGSQRGRLQQLGQRLNFVTGLGRKKQTTFADESAAAGGAGGSATAAAGPSSTLMSATSGGDMRGMSASTGGAGVPGGVSPTLNNAEAFNPPNHPVNPFSYLATPFRVMAKTKAGAAMGRYTAAALRLKRDGMPPASYMWLWLGNFKRWHKRYFVASEAPGVLLIYKRANMKGKVWSTSLVDATVAQDDSHPRQIRLETPSGTIFLRVLRPEERQPWLTCLRDSIATYRKHKEVVDTLAAAAGGGGEGEGGHGAVAGALPSVASGAVDQDMEQRRRIRLRVHERLAELAPHVSEVERHMAALGSQLANAAAGFGHLSTPLLPHHSSVAAALSSRGTRVPGGSAEHGHTSAANNISGSGSAADAPAHSPSGPGRQSHNGRGSAGHASLAGVAAQAADREPSQERLGLLARSRSRSRAAAPGAPAATLTGAMTALMEAVRAALHADALRITTLEAENAALNKTLQIVRANANRSGARSRGLSTPGVSGAAGASTARASVAAAAAAAVAGGTTGADDDAMSDGSACTADEDAFDVVEAFDEDDDDGGPFTAHGHYPGTGDEEMEGEDDDEDAEEDAAELAQQAEVLNALEVVRQVEYIAANRNAEHLKNLLAADTPPPPDAEEDEGKGGHKGGKGRGEETDATLGEDEEDDDDDSETALMASTGAAPAGAGALIRAGSTAYDMSGRARVYEGRDRLPAPKPLGRGFSIWSILKNMIGRDLTKITMPATINEPTSMTQRMAEVLENRTLLEKAATTPNSLDRLMLVSCWLLAGYNSQPQRDNKPFNPLLGETFEWVAPDGTARYLCEQVSHHPPVSCFVGEGAGEQGYSLYGEVETKTKFWGKAIECILAGHMEVRLKAWDEEYRFNLGTITINDVILGRFWIDLSCDMKIRNEKTGETSRLVIKPCRGVLKERGKCEGTVYDAFGKEVWKISGSTMVALNAALTPAAAAERGASTEPQLIWTRPLGVPNPTEQYCMSRFALGMNDPADPIVQFLPPTDCRFRPDIRALELGEWNRATSEKLRLEEKQRAARKERKEAGIEYQPKWFKQVMFGTKEATQLATQPGAVWAWTGEYWSAREKKEWGELPDIY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQ34</accession>
    <name>A0A835WQ34_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_003765</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WQ34"/>
    <dbReference type="OrthoDB" id="553123at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="976"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="39"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="313"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="834"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="907"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="943"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1025"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1071"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="213"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="350"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="413"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="439"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="467"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="482"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="501"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="523"/>
            <end position="533"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="534"/>
            <end position="543"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="550"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="597"/>
            <end position="625"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="653"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="663"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="760"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="911"/>
            <end position="928"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="959"/>
            <end position="968"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1055"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1071"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1106"/>
            <end position="1126"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2451994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1237" mass="118543" checksum="6B31FE15DD6C4FC2" modified="2021-09-29" version="1">MLGSSLWLANVGDCRAVVCDDGEARQLTVDHKAGAAADAKAGAAGGGGGGGGTGGGGGSADGPTPSGASMTERRRLESLGVQLSADGYLQMTAPDGSCSDIAVSRNLGCAHLKKAATPTAASASSSAAAAAAAATFRRATLQYFPQHYSHHGHSYSHGHGAAAGGGAVAGAGYGHGRSGSSSFSHASRGHLHHPHLGVHHSHHGSHGSSSGHGSSGGGGGAGATAGAGGGRPHLTSAPVSVAQGMDGMMSSAVARGVGGTAVAAGTGSAPYLRGSGSSASFSGPCSASAAGSTPTSSSLLQPLLIPQLQPLQPARFDAPSDPTGFAPNGAGAHANASHHPPLFHSRSAHHASGSGPATAAAVPGSSNGGSPSYSSTRGGGGGGAAAAALAIQLQQHYSPHAAAAHLHGHSYSHFSPASASAQAQAQALHQQQLHQQPQLHHHVHLHLHHHHGRSHPHHPHHTPHHRPQLDLVREDSSQPPAATQPPPCMEPPPPSEEDRSATASATMAMAGGSGGLELGCGRLPPPLPPPQEPQPLGQPEAGGQPPPPQQQQQQQQPPQQQQQQQQPPQQQPDGAGYIGILSSSPPRDPRLRYVRAPPGQQQLQQQQPREEQQQPPQQQQQLLQPHGLDVGPPPPHLARIATSPGAGDRSRSKGGGSSGGAVAGPAEAAAAGAAPAGDLPSRASAPAPAVAAAAATHTLGMSPRPPRPPSSGGGAAVAGAIAAAAAAAGAAGGGISQASPRPPPSPAAAASPGLAERPPAAAAAAAAAAAGGHGLGPASSVGGSGGGSGGGVGGGSLLGLPPLPPSPSLPGTAAVAMAAAAAASSSSSPGVMQGGVFYHHGRSGSGGGGGSSRVRDRSPTSPFPRTSAGAITLPPLDEGSSSAEVGWSDGGAAAAAALTAMAARTQLRDSSGGGGGGGGPSSTGGGADGAAAVNGTVAAAHANGPGTIADGQQQNVGSSQGGGGGGAAVAGAATAGAGAATAAGLHRSGSGGGGASRGSSTAFELLHAESFSKWTLASAFADPAAAPAVSGGAPPPPPGTGPEAGPGAAATTGMPPLRALPAATATGAATGCAEAPASAPGSGPSGSRGRPLLQLPGDDNTPHLADGGGGGGGGGDGGGGGGDGGAGPGTLVCDGAGALIPDPDLFHYQISTDSEFLVVACDGVWDVMRNGEACRMVRRWLADGRSAAAAAEALCTSALKLGSGDNLTAVVLRFSSRPLATAPSRSMLRRVASEFMS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQ35</accession>
    <name>A0A835WQ35_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Methyltransferase</fullName>
            <ecNumber evidence="20">2.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="22" type="ORF">HYH02_004012</name>
    </gene>
    <organism evidence="22 23">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="22" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="22">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="18">Catalyzes the methyl transfer from S-adenosyl-methionine to the methylene group of 24-methylene lophenol to form 24-ethylidene lophenol.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="17">
            <text>24-methylidenelophenol + S-adenosyl-L-methionine = (Z)-24-ethylidenelophenol + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21044"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29107"/>
            <dbReference type="ChEBI" id="CHEBI:33203"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="EC" id="2.1.1.143"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Steroid biosynthesis; sterol biosynthesis.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Microsome membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="19 20">Belongs to the class I-like SAM-binding methyltransferase superfamily. Erg6/SMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="22">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.1.-" evidence="20"/>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WQ35"/>
    <dbReference type="OrthoDB" id="4310724at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030797">
        <property type="term" value="F:24-methylenesterol C-methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016126">
        <property type="term" value="P:sterol biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.150:FF:000168">
        <property type="entry name" value="Methyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030384">
        <property type="entry name" value="MeTrfase_SMT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013705">
        <property type="entry name" value="Sterol_MeTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44742">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44742:SF2">
        <property type="entry name" value="24-METHYLENESTEROL C-METHYLTRANSFERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08498">
        <property type="entry name" value="Sterol_MT_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51685">
        <property type="entry name" value="SAM_MT_ERG6_SMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="3" id="KW-0444">Lipid biosynthesis</keyword>
    <keyword evidence="13" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="14" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 19" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="9" id="KW-0492">Microsome</keyword>
    <keyword evidence="23" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 19 20" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="10" id="KW-0752">Steroid biosynthesis</keyword>
    <keyword evidence="16" id="KW-0753">Steroid metabolism</keyword>
    <keyword evidence="12" id="KW-0756">Sterol biosynthesis</keyword>
    <keyword evidence="15" id="KW-1207">Sterol metabolism</keyword>
    <keyword evidence="5 19" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="11" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="SAM-dependent methyltransferase Erg6/SMT-type" evidence="21">
        <location>
            <begin position="102"/>
            <end position="381"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004111"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004938"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022516"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022848"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="ARBA" id="ARBA00023221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="ARBA" id="ARBA00051352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="ARBA" id="ARBA00057056"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="RuleBase" id="RU362025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="21">
        <source>
            <dbReference type="PROSITE" id="PS51685"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="EMBL" id="KAG2451412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="23">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="387" mass="42043" checksum="7368AA698147AE0D" modified="2021-09-29" version="1">MAVALPAAVTSAYERLAGEFDKLSTTQKYAVGIAGGVTSLYLLAKVLKGSDRDKPTTLQLSGGSIDASKVKTEFDAYADSYGKNAGEGITDRSKTVHLVDVFYSLVTDIYEWGWGQSFHFSPKLPNKDLKASEAAHEARIAALLRLQPGQKALDCGCGVGGPMRTVAAVSGAHVTGITINQYQVDRAKSHNARQGLAPLTDVVRGDFTNMPFKENTFDGAYAIEATCHAPKLEQVYGEIYRVLKPGSYFVSYEWVSTNKYDANNAEHVKIMDEINFGNGLPEMRTWKEAEDAGKNVGFELVMSLDLATASVVAGPWYERLRMGKYTHAINHGIVSTVDALGLAPKGLKEVHHMLVEVAKSLIHGGESGIFTPMHLLLFRKPGADKKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQ38</accession>
    <name>A0A835WQ38_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ricin B lectin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HYH02_003943</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="3">Cytoplasm</location>
            <location evidence="3">Cytoskeleton</location>
            <location evidence="3">Cilium axoneme</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="12">Endomembrane system</location>
            <topology evidence="12">Single-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451339.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="542249at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00161">
        <property type="entry name" value="beta-trefoil_Ricin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.80.10.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="14"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001611">
        <property type="entry name" value="Leu-rich_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003591">
        <property type="entry name" value="Leu-rich_rpt_typical-subtyp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013210">
        <property type="entry name" value="LRR_N_plant-typ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013122">
        <property type="entry name" value="PKD1_2_channel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035992">
        <property type="entry name" value="Ricin_B-like_lectins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000772">
        <property type="entry name" value="Ricin_B_lectin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27000:SF642">
        <property type="entry name" value="INACTIVE LEUCINE-RICH REPEAT RECEPTOR KINASE XIAO-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR27000">
        <property type="entry name" value="LEUCINE-RICH REPEAT RECEPTOR-LIKE PROTEIN KINASE FAMILY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00560">
        <property type="entry name" value="LRR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08263">
        <property type="entry name" value="LRRNT_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08016">
        <property type="entry name" value="PKD_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14200">
        <property type="entry name" value="RicinB_lectin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00369">
        <property type="entry name" value="LRR_TYP"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00458">
        <property type="entry name" value="RICIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50370">
        <property type="entry name" value="Ricin B-like lectins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50231">
        <property type="entry name" value="RICIN_B_LECTIN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="11" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="4" id="KW-0433">Leucine-rich repeat</keyword>
    <keyword evidence="9 14" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-0675">Receptor</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 15" id="KW-0732">Signal</keyword>
    <keyword evidence="5 14" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 14" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="15">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032293976" description="Ricin B lectin domain-containing protein" evidence="15">
        <location>
            <begin position="21"/>
            <end position="6974"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="5649"/>
            <end position="5670"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="5690"/>
            <end position="5712"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="5821"/>
            <end position="5841"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="5862"/>
            <end position="5885"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="14">
        <location>
            <begin position="5931"/>
            <end position="5956"/>
        </location>
    </feature>
    <feature type="domain" description="Ricin B lectin" evidence="16">
        <location>
            <begin position="2437"/>
            <end position="2586"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="19"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2139"/>
            <end position="2159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="2389"/>
            <end position="2410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="3400"/>
            <end position="3462"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="3877"/>
            <end position="3908"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="4041"/>
            <end position="4079"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="4242"/>
            <end position="4267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="4677"/>
            <end position="4700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="4815"/>
            <end position="4925"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="5603"/>
            <end position="5624"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="6124"/>
            <end position="6150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="6270"/>
            <end position="6392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="6528"/>
            <end position="6566"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="6619"/>
            <end position="6715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="6756"/>
            <end position="6784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="6797"/>
            <end position="6827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="6901"/>
            <end position="6974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="23"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="2143"/>
            <end position="2154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="2392"/>
            <end position="2401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="3400"/>
            <end position="3457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="4820"/>
            <end position="4872"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="4900"/>
            <end position="4909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="4910"/>
            <end position="4924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="5606"/>
            <end position="5624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="6315"/>
            <end position="6331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="6365"/>
            <end position="6392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="6543"/>
            <end position="6553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="6630"/>
            <end position="6672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="6756"/>
            <end position="6766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="6901"/>
            <end position="6918"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="6919"/>
            <end position="6928"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004236"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022614"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00037847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00458"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG2451339.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="6974" mass="714935" checksum="1C2218503089D2F9" modified="2021-09-29" version="1">[encoded data, 6974 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQ69</accession>
    <name>A0A835WQ69_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">PDEase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_003986</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451384.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WQ69"/>
    <dbReference type="OrthoDB" id="568146at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="7">
        <location>
            <begin position="332"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="33"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="240"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="240"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="407"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="407"/>
            <end position="411"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="411"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="448"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
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        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
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        <location>
            <position position="449"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
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        <ligand>
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        </ligand>
    </feature>
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        <location>
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        <ligand>
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        </location>
        <ligand>
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        </ligand>
    </feature>
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        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2451384.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="721" mass="76874" checksum="AD0410F0B5DBD62E" modified="2021-09-29" version="1">MKASSGCPLCPLKVPARDAPALEVFNHFCSPRHSRGNSGNVASSPARARRGSIDVPGGFGGVPVDDPLTPSSPWWTHIPPHREDDDLSTRSAPLGGLAGGVLSPRQSLCCGTATPAGGGAGGRSRLAVGGSSYHMQDQVMHDLLEARRLSRSKAGTPADLMLAMLSNMLLGLTPDLRDVELAREMLLKHADPYQPLNLDTQMREANLDADVVGSLMQQLGASGSAGGGVGQGQGQAAAQAAVAGSHGAQGDQSSGSGDEFLLPRLSSMTEVDSLRDALALLLGVGRLAPLALPSPLQSGCVAEGDEGLATASVDDSASDTDGGVALRPCQWVPPPVIDEVERALALADEWKYDTWHLAEVTKGHALSCLAFYLLHREGLVSQFRIEPTKLARLLRTIEQGYADNPYHNSTHAADVLQTFHVLLRGAGLTTHYLDRVGLLAAYFAAVVHDHGHPGLTADFLIATSDPLAVRYNDRSPLENHHGASFFSMLLQPDMNVLTHLAQHEKNAFRKQVIDLVMATDMKQHFTLLAQFNTAHRLSAYNKDVGPWALANTWRGHRPSHGIECETTSGADEVGASNLSFTVHVATDPKPLDDTERTLTLQIVLKAADLGHLGEDVEVHQRWVRALEEEFFRQGAKEQALGLPISPLFDRTKQGVSKSQVGFYDFIALPLVHALASAFPGARPLLACYVTNYDHWRAVEKAVATAAAAAAVASTSADGGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQV0</accession>
    <name>A0A835WQV0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_003059</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WQV0"/>
    <dbReference type="OrthoDB" id="1910737at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008821">
        <property type="term" value="F:crossover junction DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045290">
        <property type="entry name" value="MOC1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36015">
        <property type="entry name" value="HOLLIDAY JUNCTION RESOLVASE MOC1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36015:SF6">
        <property type="entry name" value="HOLLIDAY JUNCTION RESOLVASE MOC1, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="570"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="8"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="588"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="638"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="663"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="691"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="703" mass="69889" checksum="F8CBD05B34E73039" modified="2021-09-29" version="1">MRTHATRSKPASQSSSRATSSGPAVATRPRRSRRSSSSDAQDQHNDSANGFSTESSTQTSASLLSAPAAAPPAPLPAVANPTWRTPPTAEAARRITLAASASAAYSANSAAAASAAAAAATAAAASGAAGSGPSSSTATVTRGAASAAGGVAAAEFLLSGALSRAVAASGAGAATKPHQRKAPPTPAAQGPSGATSPAPWRTQVDSAEQAARSPGPSAATGEAASGSARPGTPAHLPSLPHAAAHAPPPPTARGGAAASSGHAVASSTAAAAPAAGAGTVLPTRHIVAAVDPDLNGALALIYWDEDPNDPTTATASGPGAATTDAAAAAAAAAAAAAGPAARLAALAAAAPSGSGAAAAAAEAAAAALLWLPTPPRPPADPARWRVCVWDMPVSASERQKRTASGQVARRSYVEVPPILPGDGNIAAYTSLWSTGSWLGLLTGMGFTVGSTPVRRWKTDLGLYGAQGKDASLALARAVFPGQEPILRHKKNHGRADALLIAAWALGACLPRGLGASLKRNGITLDQLLEQQPGTVGLVWGPPRPPAPTDAYGNLLTPEQDIWDEIEAAESKVERKTQARATSRRRKAAASGAGEDEAGQQQEGQERLGQVAEAVAAEVPKRRRTKKATAAADEEEQEGEAKQQAEARGETEKVASRAKRMRKAIGGASASASSTKSGAKRSSTGTRRRAAAKGAAVVGESESE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQW1</accession>
    <name>A0A835WQW1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">PUA domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_003734</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="8">Belongs to the methyltransferase superfamily. RlmI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451961.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WQW1"/>
    <dbReference type="OrthoDB" id="269872at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd21153">
        <property type="entry name" value="PUA_RlmI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd11572">
        <property type="entry name" value="RlmI_M_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.130.10">
        <property type="entry name" value="PUA domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.750.80">
        <property type="entry name" value="RNA methyltransferase domain (HRMD) like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025714">
        <property type="entry name" value="Methyltranfer_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002478">
        <property type="entry name" value="PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015947">
        <property type="entry name" value="PUA-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036974">
        <property type="entry name" value="PUA_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041532">
        <property type="entry name" value="RlmI-like_PUA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42873">
        <property type="entry name" value="RIBOSOMAL RNA LARGE SUBUNIT METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42873:SF1">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13847">
        <property type="entry name" value="Methyltransf_31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17785">
        <property type="entry name" value="PUA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00359">
        <property type="entry name" value="PUA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88697">
        <property type="entry name" value="PUA domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="3" id="KW-0698">rRNA processing</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PUA" evidence="10">
        <location>
            <begin position="251"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="170"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="431"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="34"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="9">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="180"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="436"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00038091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00359"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2451961.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="705" mass="72031" checksum="C23D814F77C00037" modified="2021-09-29" version="1">MHSTSVAGTRAGAAGVATTPVPLTMRPPPLLPHGPTRAGRRATALLPRATRDAPASGRGSRPAGRGSRDGASAAGRAPRRAPGSGGGGRGAGGGLPPKGRPPKSAAPKRADAEDEDEPADVDGEDAAAAAASSDGVDDLDALLNNADAVKQLRATLLAGLTAQHEAAMREEAGLGEEEGASSSAPATASAPAAPAAAAPKAPAKQPAAPTPAPAPEPVVAAAAAAAAAAASAAAAAAAAAATASESPAAAPLVVLKKDKARLFVHGNPMVYGGAVDCVIGRPPPGVGDVVVVADANRRPIGWGVFNPHSMFRVRMLALQAEEDADPRGPLAAARLDVGALLRLRLAQAAALRRSMGLPGPDTNVYRLVNSEGDRLSGLVADVLGDTVVVQVVAGWVQRYRPEVEAAIREATGLSRIVWRPAWRILAEEGLTPPPEEQVQQPAKEQQQGKAGQEEGEGEGEAEQQQAERVEVREAGLRYWASPLGQKTGFYADQRDSRAFLGRVVRAQVQQQQQQQAAAGSSSSGSSSSSGVSVLDLCCYSGGFALSAAAAGASRVVGVDSSDAAVQLAADNAQLNGLAGVASFVRADVSDYMREAVQQGAQYDVVVLDPPKLAPDRNSLARARIKYTRLNTLAMRLVKPGGLLITCSCSGAMTQSGEFKDMVIEAARQAGRQATALREAGAAPCHCLNPAYPEGEYLTNLTLRLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQY2</accession>
    <name>A0A835WQY2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_002701</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452459.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WQY2"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013111">
        <property type="entry name" value="EGF_extracell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062:SF376">
        <property type="entry name" value="EXOSTOSIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07974">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032832935" description="EGF-like domain-containing protein" evidence="7">
        <location>
            <begin position="27"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="8">
        <location>
            <begin position="86"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="70"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="70"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="90"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="5">
        <location>
            <begin position="109"/>
            <end position="118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2452459.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="798" mass="83512" checksum="C23852410C7798F3" modified="2021-09-29" version="1">MNQQLQRWITCLLVFGVLLRSGAARGREVFTAGRRLRSERSLVVSSTAGALRSVSAGGTQAQLDATRAALQAGDADSSSDGSLASRPSRCPGRCTEFGTCNEELARCDCPIGRNGTDCSEEVPSGPALQQVCARYGHTLASCTRVDAAGCVNGCNGRGRCVGGFCHCRPGFFGADCSLSLSLSRAVPAAAAGADDSSSSSSSSTAARPAVELLAGQGYAVRASGPRIYVYELPPELNVYGNLDRLDRPLMYMVWQRLLSAGVRVADPAAADFFFVPVRVRLSYDSEKLVQAVSYIRSTWPHWDGQPGGGGERHIFVHTGDWGRDELSEEAQALTRNATWLTHWGLARDHEFAGWKAAHRPGRDIVVPLVLQASLLSSYRLTRTTPLHPGAAAGGRKLRPRSRTMFFAGRVCGSRAQPSTNGTYPNCPDVLGKEDAYSAATRQMAFYHHHNRTGWKMVTSSKTYALDMLGSKFCLAPSGGWHGAWRGVAGKRAVISVLMGCVPVTVTDGLLQPFEPELRWDRFAIDVRERDIPVMHAVLEGLKADQVSEFQSNLRCAAQHLFWSSLFGSVFGEDGRYDAFETLMQVLRMRATYPSLGPEEYAYVDASFAAFMKCEAHLPGAGAATAAAAGAGAAGSGSSRSRGSGVAAVAAAGGLLGGFNGTGAAGGLLDVAKPDLGQALAAQRATAAGGGSSSSSTDGAAASGAAAAGGGAAGAAGGGLLPAPRALLLPAELVGEGGQGVTRQELCTHSELPVPPGSGSLPAAGSCNRCPRRRGRLLNPGGTICCNTKDLAKCPRLWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WR63</accession>
    <name>A0A835WR63_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">proline dehydrogenase</fullName>
            <ecNumber evidence="2">1.5.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_003753</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the proline oxidase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.5.5.2" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451982.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WR63"/>
    <dbReference type="OrthoDB" id="5464at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004657">
        <property type="term" value="F:proline dehydrogenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010133">
        <property type="term" value="P:L-proline catabolic process to L-glutamate"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.220">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029041">
        <property type="entry name" value="FAD-linked_oxidoreductase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002872">
        <property type="entry name" value="Proline_DH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015659">
        <property type="entry name" value="Proline_oxidase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914:SF0">
        <property type="entry name" value="PROLINE DEHYDROGENASE 1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13914">
        <property type="entry name" value="PROLINE OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01619">
        <property type="entry name" value="Pro_dh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51730">
        <property type="entry name" value="FAD-linked oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-0642">Proline metabolism</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="652"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="683"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="713"/>
            <end position="737"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="8">
        <location>
            <begin position="506"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="900"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="904"/>
            <end position="937"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005869"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012695"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2451982.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1023" mass="105443" checksum="D530F1CB9F5074D7" modified="2021-09-29" version="1">MTRSPSAQLPLSLWKSTLPGASRGGLPVVLEGISATLSTHGVCRSSGVGGSTGLHDSSQSRRLGPQTLGCSFHQPRPLAPIFRAAAGVTLGGAKFSAAIAHGIDASGAIIVNSGVGGGWRAYGAAAAASALARRAHPDGGAAAADSAPDILIAFSRNPPGAHHEDEATAAATTAAAAAGPTAATAVHGGHHEDEELYHLISPALAGATAAGPVLMPMTGTATAEHSPAGATAPAATTTAAAAAARADARPAPPLSFTDHRAVFEGQSTWQLLRAYGVLRACGINVLVDHAEALLSASRRLPLLPAVVDAAVKATFFAHFCAGEDVAEVRRTVERLRASGVGAILDYAAEDDVGANTAGGATDNTTATAAAPAAATTAASPPAAAAAASKAVVAPAAGAAGSGRGGGIDTAATATAAAATAADAAEAPAAGAAGAAAVAAGDVVLSPRALGVVGRTYDYESEEQCDRHVHHFLSAIEMAAQQPGRPAFAAIKITALGNPALLQRASAAVAMMHRLFARFDEDGSGFVDRHEFERQWRRLVAGAANSPELEAVIRRQGEETYRWLDRQGTGKVDYVSWCSRLDLRHLPLLAARIAEGGAGATAGGGASSAEAGSSGSSSRAVADMCLDENEVELMAALLGRLQCGLLPACACGLLLRLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLLTAANGCLVQTLVAAALRADVRLMIDAEHSYFQPAIEHLTLRLMQQHNRGPGGPRLLNTYQAYLTDCPARLARDLERARREGWVLGAKLVRGAYLHLERRRAEQLGYPSPCWPDLAATHACYDACAEQLIAAAAEGRAEVLLGTHNQASVEAAVAAMAQHGLVPPPQQQHQQRASASAAAAAGPSGTSTNSDSDSASDAAAPPLPPASDRVMFGQLLGMSDHLTLTLGKAGYRAYKYVPYGQVGQVMPYLLRRAAENRDIMKGAKQDLSMLKSELRRRAAAAVGLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WR78</accession>
    <name>A0A835WR78_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">F5/8 type C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_004422</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fucolectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000009">
        <property type="protein sequence ID" value="KAG2451155.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WR78"/>
    <dbReference type="OrthoDB" id="550804at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042806">
        <property type="term" value="F:fucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010185">
        <property type="term" value="P:regulation of cellular defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001868">
        <property type="term" value="P:regulation of complement activation, lectin pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051941">
        <property type="entry name" value="BG_Antigen-Binding_Lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000421">
        <property type="entry name" value="FA58C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006585">
        <property type="entry name" value="FTP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45713:SF6">
        <property type="entry name" value="F5_8 TYPE C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45713">
        <property type="entry name" value="FTP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22633">
        <property type="entry name" value="F5_F8_type_C_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00607">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50022">
        <property type="entry name" value="FA58C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="F5/8 type C" evidence="9">
        <location>
            <begin position="6"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="160"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="161"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2451155.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="356" mass="38042" checksum="BD78844079BC3CEE" modified="2021-09-29" version="1">MYGRLPPGTNLALNKPAYAATAMDSRYPPSEAFDGIKTDDENMYHSNYWSNSDSYWLSVDLGATVNITGIVIYNRPVFEVRLKNAEVRVGNSQVTNPSEALANPNTLVWTVSGVAGISQHVLTLDPPVAGRYVSIRNMNVAAVSGDAVLNLREVEVYGVLPPSPSPPSPAPPSPSPPEPMPPGTNLALNKQAYGAPSFYYGGYLLPSFAVDGTINRDLNCYHSASNVAVDRHWWSVDLGSVVTINGLAIYPRNGYQRRLKNAEVRVGLGPVTSEAEMLATTNALVWTLSGIDGVYPAVKTLATPVIGRYVSIRNMNLGATSDEATLNLAEVEVYGAPLPMPPSPVPTPPTIGAFAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WR87</accession>
    <name>A0A835WR87_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP-2 complex subunit alpha</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_002861</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Subunit of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Adaptor protein complex 2 (AP-2) is a heterotetramer composed of two large adaptins (alpha-type and beta-type subunits), a medium adaptin (mu-type subunit) and a small adaptin (sigma-type subunit).</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <location evidence="1">Coated pit</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Cytoplasmic side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adaptor complexes large subunit family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WR87"/>
    <dbReference type="OrthoDB" id="413467at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030122">
        <property type="term" value="C:AP-2 adaptor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035615">
        <property type="term" value="F:clathrin adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.1230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.310.10">
        <property type="entry name" value="TATA-Binding Protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050840">
        <property type="entry name" value="Adaptor_Complx_Large_Subunit"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017104">
        <property type="entry name" value="AP2_complex_asu"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002553">
        <property type="entry name" value="Clathrin/coatomer_adapt-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003164">
        <property type="entry name" value="Clathrin_a-adaptin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008152">
        <property type="entry name" value="Clathrin_a/b/g-adaptin_app_Ig"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013041">
        <property type="entry name" value="Clathrin_app_Ig-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009028">
        <property type="entry name" value="Coatomer/calthrin_app_sub_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012295">
        <property type="entry name" value="TBP_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22780">
        <property type="entry name" value="ADAPTIN, ALPHA/GAMMA/EPSILON"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01602">
        <property type="entry name" value="Adaptin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02296">
        <property type="entry name" value="Alpha_adaptin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02883">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF037091">
        <property type="entry name" value="AP2_complex_alpha"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00809">
        <property type="entry name" value="Alpha_adaptinC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49348">
        <property type="entry name" value="Clathrin adaptor appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55711">
        <property type="entry name" value="Subdomain of clathrin and coatomer appendage domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0168">Coated pit</keyword>
    <keyword evidence="3 7" id="KW-0254">Endocytosis</keyword>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="4 7" id="KW-0653">Protein transport</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 7" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Clathrin adaptor alpha/beta/gamma-adaptin appendage Ig-like subdomain" evidence="9">
        <location>
            <begin position="816"/>
            <end position="929"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="541"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="573"/>
            <end position="602"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRNR" id="PIRNR037091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2452624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1062" mass="110941" checksum="1B98B9E03CD36617" modified="2021-09-29" version="1">MACSLLLQENDEFLRLAINAIHLDLTSRNEAFQALALSFVGNIGGQEMAEALTLDVLKLLTSGASRPLIKKRASLCLLRLLRKTPADAPLVVAADTFSPTMGALLEERDLGLLLCSVTLLHGLVARSGTGGYETCQGRVIKILERLVRERERIPPEYLYYGIPSPWLQARCLRALQLFPPPDSATERKALHDVLQNIIATTSAEAAKNANPNKTNALNAILFEALAVALHHASATNTAIAATGPDAANDRATLGSCLSLMGRYLAGKDPNAKYLALDSLARLAGAMPEVLEGVRHHQATVMASLKDPDVSIRRRALDLLFAMCDAASAPEVVGELLKHLVVADFGVREELVLKIAILAEKFAPSMQWYMDVVLQLLERSGDFVSDEIWHRAVQLVTNNPSMQEYAARNVAEALKRGAAHESLVCTAAYILGEYGRLIRAEVPPAEQYRLLHGAFPAASQPTKGLLMTALLKIYLLEPTNATLSRDVRELFDRYKRFMDAELQQRATEYLALAANPQAATASFILPMPAWQIRESSLIKRLQPEGSEAAGEGGPAGASSLAAADAPSTLAGANTSPLLSVPMPGSGLSPALQPGGGGGDLLSMDSASRGGAAGNGAFGAAPAAVAAAAAAPPPKPATPVDLLSDLFSDAVITPSAAPAPAPMPAAAAAGYPGAYPGAPAPTGYPMAVPSAYPGAPTPAYPGAPAPAYPGYPGAPAAVPQAAAPGYPGAPAPAANPFPSPYGAPPAAAPAPAATANPFAANPFPAAVPAPAPAPVPVAVPAPAAAHADPFGDSHFGAQPAPAPVPPPVPTGDVNAWYSALLLKERGILYEDQYLQIGLQSQYTRGRGNITLYFGNKQAGAQLTNVSLVQTVQSPGVAMAPGPMPAVLEPKQQLQVPISLTCLGPFTEPPALALNYGVAGAPALNAMQLRLPVAMHKFMAPEVHIPKETFFDHWRAAQPANKAQEMVDRGAAGPVSPETVQGLMRMLHLGVEHGYLDPSPHNEAGAAYWACGPADPQRVVLCCCRVEANPQNRAQFRVTVVADQPELAQSVHALLVAQLKAAPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WR96</accession>
    <name>A0A835WR96_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Patatin</fullName>
            <ecNumber evidence="4">3.1.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_002872</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">Lipolytic acyl hydrolase (LAH).</text>
    </comment>
    <comment type="domain">
        <text evidence="4">The nitrogen atoms of the two glycine residues in the GGXR motif define the oxyanion hole, and stabilize the oxyanion that forms during the nucleophilic attack by the catalytic serine during substrate cleavage.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the patatin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.1.-" evidence="4"/>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452638.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WR96"/>
    <dbReference type="OrthoDB" id="545248at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047372">
        <property type="term" value="F:monoacylglycerol lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016042">
        <property type="term" value="P:lipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1090.10">
        <property type="entry name" value="Cytosolic phospholipase A2 catalytic domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016035">
        <property type="entry name" value="Acyl_Trfase/lysoPLipase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002641">
        <property type="entry name" value="PNPLA_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32176">
        <property type="entry name" value="XYLOSE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32176:SF92">
        <property type="entry name" value="XYLOSE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01734">
        <property type="entry name" value="Patatin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52151">
        <property type="entry name" value="FabD/lysophospholipase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51635">
        <property type="entry name" value="PNPLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 4" id="KW-0442">Lipid degradation</keyword>
    <keyword evidence="2 3 4" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PNPLA" evidence="6">
        <location>
            <begin position="32"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="348"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXGXXG" evidence="3">
        <location>
            <begin position="36"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="GXSXG" evidence="3">
        <location>
            <begin position="155"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="DGA/G" evidence="3">
        <location>
            <begin position="433"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="348"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="3">
        <location>
            <position position="157"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="433"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01161"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU361262"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51635"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2452638.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="714" mass="76613" checksum="B6FA2CB1CFF1CA61" modified="2021-09-29" version="1">MAATPGVWPQVVRPAALRPSAGPRIGRTPTLLSLDGGGMRGLISAQVLVELEDSIKQVLWKERLIEDVKPLLEDAAARKVPGLGSVAARLAEYESQVSSAGFTINEGHEAAERWDLRWDDYVKWQSSLLAPPKDWAVIKQCFDVDIGDWFDQLAGTSTGGLLALYLAARGGAGEARPSDPTLRPGSAAASSAFYEENGEKIFASGTEQARKAKMVQNFLDTAGYARHTKDGLEEVLHGVFGDRTLKSLEEHGANVLVTTVDVTSMRTGAFFHQSAKPSPAQIAAEDSNKDRAAVTLHDDSGLFTPLRKADKGRVVLVRNPTSPNRVETAESRQAMGWLDGWVNHGEDPTGGGRARGGTNGVGAGGVRTTTPRELRFLSAIGGWVAPMHSELLDFKLVDVARATSAAPTFLPPMTIMRPEGAANWPEEGRTFVDGGLGNNDPVFMGLAQLLQRNNNAGLQDCAVLSIGTGTKVAFDGYNPVRENPKLKGLLFWGMQLGLFDKWARSFAQAPVNGLKEKGPRAVVNAAKAVGGLVGLTMSINGEDKENILRSILYGLLHLPEGTYLRIQITDEASAGIQPKSDPQQPREVTPAVGGIAGAAEPTGVVSSPWGSLAPKDAKQEEQWRKALAAMDNPNPEILSAYKEMGKALAENYRNRIKWWVRCFLFGLEDAAHSPLLVDVAPKPLEIEHEDKVAGGKFITAAQKRPSRSGPAGTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRY1</accession>
    <name>A0A835WRY1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cytochrome c-type biogenesis protein H TPR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_002163</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452817.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRY1"/>
    <dbReference type="OrthoDB" id="1926212at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045892">
        <property type="term" value="P:negative regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044650">
        <property type="entry name" value="SRFR1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056413">
        <property type="entry name" value="TPR_CcmH_CycH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44749">
        <property type="entry name" value="SUPPRESSOR OF RPS4-RLD 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44749:SF1">
        <property type="entry name" value="TETRATRICOPEPTIDE-LIKE HELICAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13432">
        <property type="entry name" value="TPR_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13181">
        <property type="entry name" value="TPR_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23914">
        <property type="entry name" value="TPR_CcmH_CycH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="9"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0802">TPR repeat</keyword>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="352"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="395"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome c-type biogenesis protein H TPR" evidence="3">
        <location>
            <begin position="418"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="429"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="1">
        <location>
            <begin position="463"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="109"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="109"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="138"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="200"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="218"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2452817.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1046" mass="112049" checksum="A80B949F05B895B4" modified="2021-09-29" version="1">MLVNRGFCHQRVQLYRKALKDYDAALEAVPRLPLALYRKGQVLAAQKKYEEARAAWNEALQACNERSDAQLVLDISAAIKDPTGVKAGLSALVAPLTADASKAAAAASSSSAASAPATPSQSYSSNGGGVAPAPAVPVPSSSSSSSSGAPAPPGPSKPTAQAADPVGRQEHSAAAAAAPSTGRGGVASTSAPNGGGSSNGGAASKSSSKSSSPPPPAASKAPAAAATKLGSSSSTSAGSKGAGAVGECDVEEVDCVAGQKAARAAATGGPGGIASPDMQTMLNNSIAIQLAVTQINSGNIVEAEAILDKVLIKTPRELGARVARGTARALRRDLAGAVEDFGVAIEVEPRYADSWKRRGQARSALGDNEGALADLQKAIDLAPLFGGPDSAQSRAECYVEKGMIYQKMRDYRRACRELQQAVKLDGSNAQAWNVLGLCSTSQGDIRDGVRAYEKAVELNPKLKEGWVNMGQALKEEGRTKEAERVLVKALALDPPDQPAVHVLRVLAQMKQQKGEHAAAIKLLDRALPVAEARDEQVIEVLYLRAICYHALGATREAVRDYDDCLGHVPKTGIANVSEEARQFQFLSFYQKDIALYLYHALDRQAKDFCPDSELPAVFKELWCKKGPPTAELISHFPPQPPLPLTPAPLPPISAAELERLRPLTSAADQLGILLQNHHQGFLPNVRQQRAAGYAAVELAQALREVVAARRAGRQVWVRSEGSSGQAGASGRHLFGWRDAMDIVVKWRQLSEPNDQVVWVDLLTRREFEQGFGSHTPMFSGQTKCVRYYMNFARALELQKEVLLREGHAFDASNNTIPVDSESQRAAIRAAKTAEDMYQVIQLDSWVVVPIHSVARPEHMMEGTRLTLVRVPNQPDAYEFSIRTPVTPPRWKDFDVELEAAFEGILQAFVDDDQPLLASRIMTYCYYWYNFMPLARGTAAVGYTTMLGLFWAAGMPVTATIPKDYQVDWEAILAQHPDQFTASVSAWLYPPQARGQPAPAAAELEAAGSGKVPTFPPIDSLPPVSEVLGSIRQRIFALNGENSKRYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRZ4</accession>
    <name>A0A835WRZ4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="3">1.3.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_003277</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="9">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Dus family. Dus3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="3"/>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452253.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRZ4"/>
    <dbReference type="OrthoDB" id="259935at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="14">
        <location>
            <begin position="2"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="252"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG2452253.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="281" mass="31136" checksum="9CD8A857492C1CEF" modified="2021-09-29" version="1">MDINMGCPIDLVCDKNAGSALLRQPKRMEQIVRATATALGEVPLTFKTRKGFNDGEDVAHTFLHKAGEWGAAAVTLHGRTRQQRYSRLADWDYIAQVGRNCATTGLQLVGNGDVFSYTDWNAHMGESGGHLASLMIGRGALIKPWLFTEIKEQRHWDISAGERLDLYRQFAAAGLEHWGSDSRGVESTRRFLLEWLSFTHRYVPVGLIEVLPQAMNHRPPAYRGRNELESLLGSDDPQDWLRISEMLLGPPPAPISFAPKHKSNSYASPPGGASEADMARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WS83</accession>
    <name>A0A835WS83_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">MATH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_002956</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WS83"/>
    <dbReference type="OrthoDB" id="660257at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055327">
        <property type="entry name" value="TRAF1A/B"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47477">
        <property type="entry name" value="TNF RECEPTOR-ASSOCIATED FACTOR HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47477:SF8">
        <property type="entry name" value="TNF RECEPTOR-ASSOCIATED FACTOR HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00061">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="2">
        <location>
            <begin position="72"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="353"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="440"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="808"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="440"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="502"/>
            <end position="522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="535"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="638"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="719"/>
            <end position="763"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="808"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="824"/>
            <end position="850"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2452725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1108" mass="116031" checksum="BE8C0E1B465954DF" modified="2021-09-29" version="1">MSKVNQSRIREALTAGTNVKEKGPPVADGILSVTPDTPEMLEWRSRSALDVAETSSTFLDDEDDGPKPHELYGKFTWKIENFSEISKRELRSNVFDVGSYKWYILVYPQGCDVCNHLSLFLCVADYDKLLPGWSHFAQFTIAVVNKDPKKSKYSDTLHRFCKKEHDWGWKKFMELSKVLDGFTVADTLVIKAQVQVILDKPSKPFRCLDPQYRRELVRVYLTNVEGICRRFCDDKKARLSWVREEGNAFRHFWASLTPEQQRKYLTDKGEVILKAVVKQFFNEKEVTSTLVMDALYSGCKQIEEHSRTWLEGKCSDNAPVVLIKAERNSFTLCGDLMEIADRVQKDYIPAAKDDNKAMQPNDGLTLRSGQDGDDYRRDSIERDEKRLAELGRKTIEMFVISHIFCEKLEIAYREAEALKRQDQLIAEEFEMARLEESKAQAKAMADKEKKAKKKEKMKQKKEAEKLKREAEEAERKAREEELRRQEAERKAKEAEKKRLEDAQAQPLAQQQQAQQQPHQQQARKQSKGKEDKKAVQQQQQQQQAKAKQPAAAQQQQAASRPAAGPSASGPPSLSSIAAAAVSESAAAAAASASSLPERPGANEDPSSDSGSEEVGTVNQATGAAESSGDGEDEVEQVASRGAAAAGAAASDSDGDSDGRAALEEEVTILRAQVSQLQRALAERDAEVYSLRAQLAESHLAQVHLAQQLAEAVAKEAPVASSNARTSGTNTSSSGSAAADGSLGAGREAAAADGSSSAATAGSRSEAERGPGKSDAAAANGPKEVLSTSTVPPSAAAAAAAAVRRMQGGPAAPSAAAQNHDAGHHGAASRSAAPGAPAAVAGRGAPSGASGSAAAAAAADLGSAGSMMQRSTSATLPSAAPGAGTGSATFTPAQLAAAAAATANGRGREAAAGASGATAGATAAVGAGAKSFLPAGASSATSASGTASSAAATSNGISGVLHSSSGAAPAQDGLPSYRNAAAGVLAAGQPSGSATMVSVSTAPMIPAPASAAAAGVGQGKRVDEGAGAPAATAAARLGVSAPSTDGFSATNARIIMQQAQQQRSSNMAFSTPTAVPPASAKRMAASTQLDSPGLEDFAHINMIDDLLTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WS95</accession>
    <name>A0A835WS95_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_002632</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WS95"/>
    <dbReference type="OrthoDB" id="543833at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032622366" evidence="1">
        <location>
            <begin position="27"/>
            <end position="79"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="79" mass="7819" checksum="207F0B607CCC3F99" modified="2021-09-29" version="1">MARSTLAAVALLVAAAAMLVAPGADAGRLGVSRAIGGSDANVLFGRRLLDTCRTCSEMASCITATCVSATSTNVSTTAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WSX4</accession>
    <name>A0A835WSX4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">CREG-like beta-barrel domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_001829</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WSX4"/>
    <dbReference type="OrthoDB" id="2138282at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.110.10">
        <property type="entry name" value="Electron Transport, Fmn-binding Protein, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055343">
        <property type="entry name" value="CREG_beta-barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012349">
        <property type="entry name" value="Split_barrel_FMN-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13343">
        <property type="entry name" value="CREG1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13343:SF29">
        <property type="entry name" value="PYRIDOXAMINE 5'-PHOSPHATE OXIDASE FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13883">
        <property type="entry name" value="CREG_beta-barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50475">
        <property type="entry name" value="FMN-binding split barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CREG-like beta-barrel" evidence="2">
        <location>
            <begin position="121"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="26"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13883"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2453613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="369" mass="40178" checksum="EC57F31A0F645639" modified="2021-09-29" version="1">MQAQQLLRHSLGAQPSSCGRAPAPVCRRQAAPRPCLRARAAGADTPQPQKQDGAPGGKPTASKPAETLNLAYESDKQKVAAATKVIMESPVKTTGLHRAPLSGGVKTATKRYELPSPPVAVRNLVEHARFGHLCTMMSGMHHRRAGYPFGTLVDFASDGAGYPVFCLSPLAIHSRNLIEEPRCSLVVQMPGWTGLANARVTIFGDVYQLPADLQDSAREIFIAKHSNERKERWVSGNFVYFRMNRIVDIYFVGGFGTVQWIAPDEYLASTPDEIVLNNPNHILTVLNEQFAPVLRAKLGTVARPLDELMFISIDASGVDIRVRTGPEFSVERIGFPIKVTNLTQVMNAMRQVVTDMSKAPTPAASGEAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WSX8</accession>
    <name>A0A835WSX8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">WRKY domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_003251</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452221.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WSX8"/>
    <dbReference type="OrthoDB" id="1918969at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="2.20.25.80:FF:000006">
        <property type="entry name" value="WRKY transcription factor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.25.80">
        <property type="entry name" value="WRKY domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003657">
        <property type="entry name" value="WRKY_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036576">
        <property type="entry name" value="WRKY_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044810">
        <property type="entry name" value="WRKY_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31221">
        <property type="entry name" value="WRKY TRANSCRIPTION FACTOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31221:SF193">
        <property type="entry name" value="WRKY TRANSCRIPTION FACTOR PROTEIN 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03106">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00774">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF118290">
        <property type="entry name" value="WRKY DNA-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50811">
        <property type="entry name" value="WRKY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="WRKY" evidence="8">
        <location>
            <begin position="110"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="domain" description="WRKY" evidence="8">
        <location>
            <begin position="359"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="163"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="234"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="306"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="414"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="604"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="20"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="260"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="285"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="436"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="470"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="612"/>
            <end position="623"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50811"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2452221.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="642" mass="67472" checksum="E44FC1C0F4643950" modified="2021-09-29" version="1">MDSSIPFPRPINARGPAPGQTPSQLSSLPPSLQARLGLGATHDSPVLLPLLQVEASPTTGIHQLCPPLFQPAQPGRVPLPIPARTEAASAAPEPARAVKREYEPRAGNGKQSVANSDGWQWRKYGEKLVKGSPNPRSYYKCSHPGCLAKKIVERSDSEGTVLSTEYKGDHCHPAPSAVKASRFKPKPKAEPPAMAPPPAVGPVDASLPVGFPPGANGRAGLHLSGGDMLPIPEALKSDFPVPHPAGGAVAHEDDTDTSEPEPAAALKAAPQDSRAAQAAATAIRKVRDSAESPSKRLDMLAAYAEEAERQLKSNSNSPEQGPSAKRQRTEAGAVRTRANPEEDDEGSGAPSTSGMQRVVDITNMDDGYRWRKYGQKQVKGSPFPRAYYKCTHMGCSVRKHVERSAEDETRFVVTYEGTHNHRPPTGSRRRNAKDVAEDDEDYEGEDAEEDSSQPTSPQYGHVTGSGGSGQQAASKAAAQGAPLHPSGAQPASADFGQQLQQLSTSLLASTVLQQAALSGVLPLIQYNSLSSEALASLGVNSEALQGVEQLNPLNLNLTSGNLADLTNLLRQHAQLDLALAAQAQAIDQANASWDPLACLITPRPNVSPPGQGPAAGQAAPSAGTGRQTKAAVFPKQVATTEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVA7</accession>
    <name>A0A835WVA7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_002461</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVA7"/>
    <dbReference type="OrthoDB" id="21470at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47423">
        <property type="entry name" value="G-PATCH DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47423:SF2">
        <property type="entry name" value="PROTEIN SQS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="2">
        <location>
            <begin position="1062"/>
            <end position="1108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="318"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="730"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="856"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="82"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="95"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="409"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="626"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="649"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="677"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="741"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="868"/>
            <end position="878"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="919"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="931"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1029"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2453135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1110" mass="110670" checksum="450500EF0B7888B6" modified="2021-09-29" version="1">MGRRRKKGPAFVLGEEQEFPGEATEGPLGFEEAYVQIGGVRITNMGFTPHAAAGGQQQRRQQQRQQQRQQRSTPGSGRGRRGGGMLRGGGGGGDPDSCSSSSGSDGEGLDEELIDYMSNVLGGVVSRGGPKARRGGKAAHQAVPSRGRAGAAAPAAAAAAAAGHGARQAGSSDEEGGGEDELEEDVEERGGGEEGEDEDGADEEDEDEDEDEDEEAAGDNAMLQRLLAGFAGRDLDEEGGSEESGGRGNLYEALLGGGGGGRDDDDDDDQEASASGASGSEDGEGAGGRGRRGKVTAVGHYYEYRMGEDGQEEVVVVVAEGGRGDTSEGAGGEDPGRPYSPGAQDEPGEDGDAGGGRGGVSVNRFPFVMRSRGQVRAAAAAAAAAVVGSPSAFMAAAASGGATPARPGRSGGGHHGAAATGGGGGQRRSGAKGAFEGALRPGEKKKLRKEKIKAKRSAREAARGFDVLALASRIAGFVSGGGGGGGGGPGDVLALEPMGTLGTGLAQSLAGVYGLRHSMQGNAKKKFLLLQSTDRTKAPDAKTQAKVDKIVAAEVARQRRGAAAGAGVGVAGAALQDVTAASVAAARRGKGGKGRGGNAAGRKGSSFSTPVAFVSSGLQRDGPPSEVEEEEDDDDDDDDSLQGDSGSSPAGGSGSGNGGMDVDEEQEDGSGGGSGSGDEEDDEEDDEEDDEEGDEEGDEEEGEERALHAGLGIMDPQRAWLAVAFGGLGFRPQEPGPGTAPRHEHPHREAGAGASEADADGTGASFFRSHFCRGPGYEAEEGELPRPVADTGAEDAAVAASSSAPAAFIGVPFALGRTGVTQLSPGDAAAAAAARAAAAAAAEAVAEAATAAAEASEAAVQTQAQGEEWNESGEEEQQDGAGSSEQEGPGPMAGEGTQAAATEEGRDEEAADGGGWQRDRKRRGGGKKAKAAAAKGNAKAAKTAKGGAAGVAGANGAAATARAAAAPAPAPAAAAPAAASRVTAVAVAAAAMGASTAGTADLLDRTSHQVKQSGKKAAKEARRQERWRQEAAGLAAPGGGVGLQMVAAAELSYEYGHFERHGRGIGSRLMERMGWSPGDGLGRARQGAAEPLRAFIRPKKLGLGAGQPQT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVB7</accession>
    <name>A0A835WVB7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_001344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVB7"/>
    <dbReference type="OrthoDB" id="552713at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="242"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="315"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="389"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="732"/>
            <end position="754"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="770"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="139"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="243"/>
            <end position="263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="315"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="614"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="627"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="644"/>
            <end position="655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="682"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="855"/>
            <end position="871"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="874"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="932"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1050"/>
            <end position="1063"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2454316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1236" mass="118116" checksum="509B13E908E8757A" modified="2021-09-29" version="1">MSKEQPKARRELNWWHSFNSWWRDEYDKLGRRPRMQEVDEWYHENAERIWGAEKPSLEATRDHAKCLRSKKELREYFQRYNAKKFGKPFTDLRQARHQSSSGAGGSGSQQHRSHTGASPGPTLSDPGTGAFTVSGAGTGPSTLTTQSPRQSSGLAAATGGGPGGAVSSAFGGPGGSVAGRYSEGGGAAGSGGVLPLGGGLGLGGGDGASSGMGLQMVAQLAARALQQQQLLQLQQAAAVAASSGGGRSGGGGGSGVGARGGSASGSQHLGQRSPGLGISADTSNTHGGGSMLSFGGAGGGGASLLGGLQAALTARGGGAGGSGSGAGTPPPSLLLGSLLAPLPQQQRSSSMRPVSRGATGTGPFSASGGNGTTTTTTVTRGAVAALHGDDDDDVAARSGGGGGGAGDGDVSARRSRLAQLLEGLTSSGLGQHLLAGDVEALAAAATAAGIDLGMSLEGIQPGDAGVSTAPRAGTVGARSSASEDGKVAAATDVDDAVDLAAALLAVRRGGSDGAVDAAGVTGLGGGNRQHSASDPLSLEPSLGPAGVARTRLDVAGDAAAHADLPSALDRLAGVKRTGPPAALDADGNLSAVSGGRPPKLLRLDQLLGLGPSAAAAAPGAGTVRAGSGAGSGSGRGAGSGVATPPSPGPSPPPATFMPSAFGGGMARSPIRGGGGAGAGAGGPPPDPFRMPGPPGGGAGGGGGSMLTAAVELAPAGAFAMLPTMLSTRDSLEPRASLPPLLPGRESSNNTRAGGVLLPTVLSTRDSLLSRASLPPPLHGRESVGTTHMGGPPTLLPPAMSLEARGSAPPPGLLAGRDSLEPRGSRLMPPPPPQLPLAERLSTPHPRPSPLGMPPSSSSAAAAAAAAAANAAGKEQGGTGHGTGTGDAREQPRQGGSGVQAAAGKEPSVPAAVGAAERQQPRQELVAAGGNDSPAAQAGAVAATVGASSGAGATAGAGAAAAAASPSAGCSVDAGGAAAGGSGDLVAAVLVAHLLSGAGLSGAVGASASEERARAAGAPNVAPDAEAEGATGGAGTAGNARPNGDVVMTEAAATAKASAQPSAPDADGHDPTADPAAPGDSKQAASGPVARGDDTTVQGGARDTGPPGPPPPLLQPADSISLAERPPPLPTPGSVKQQQSHSRGGGGGCGLVPPSTSASEVLALAEAEAAAAAAGGGQPPHLPVLVHPPDVQAGVVSAAQPGGGVTETPVQVVTVRLTLSAATVAALRNGLGGERRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WWC5</accession>
    <name>A0A835WWC5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_001845</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WWC5"/>
    <dbReference type="OrthoDB" id="277235at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000051">
        <property type="entry name" value="RNA-binding transcriptional accessory protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050437">
        <property type="entry name" value="Ribos_protein_bS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF10">
        <property type="entry name" value="S1 RNA-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00575">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="4">
        <location>
            <begin position="64"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="143"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00025453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2453630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="560" mass="60188" checksum="A62DC4875438C353" modified="2021-09-29" version="1">MLRELGRTATVKAHGRSVLRPVRGPAGRRQVAFTGVRPSVRVFAEAPAAEQAAKAIKLEDVKEGSEYEGTVTTVEEFGAFVNFGANTNGLVHISKLASGFTKNAKDVVQPGQKVTVKVLSVDAEKKRVSLELKSAVAAEAAAAEDSDDIITEPDREENAAAEEEDVEVELEEGQVEVRADLPGFEDIPFVMEEADMDAELSEAAMAALEADLDGAEIRYELEAPAYMEEVTGKVARIEDYGVFLEFEWNGKTLTGLLAKDEMKVPSAALSAEAQAALRAEWADTGFEMPEFVELPDDELDVKKYYQPGESVPAFVLESSLVDGRGISLTHFTDEEVSAEAVAAYEELEDDDDEELDKMLADAADLEDEVLAFDPEALMEEDEGEEAGAAAATGDDAEYEGVSADGLEGANGNYALGATRSGLIKGKNGYQVAPMGLPSRPLNDAVTSSGLAILGTSEVDFDGDEVQLVDYWTSEAFDNIPKDVLKKLGLKMSYNEAGEAEFEERPDFEAADVPFYLYGGDVESRAKEFVADLLSDDVDEAELPARAGRTPIVLAAAVQSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WXB0</accession>
    <name>A0A835WXB0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_001335</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454306.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="537322at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006302">
        <property type="term" value="P:double-strand break repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038892">
        <property type="entry name" value="SMCHD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22640">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22640:SF2">
        <property type="entry name" value="STRUCTURAL MAINTENANCE OF CHROMOSOMES FLEXIBLE HINGE DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13589">
        <property type="entry name" value="HATPase_c_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="331"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="635"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="931"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1204"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1247"/>
            <end position="1301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1359"/>
            <end position="1385"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1621"/>
            <end position="1714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1991"/>
            <end position="2029"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2158"/>
            <end position="2221"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2253"/>
            <end position="2275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2856"/>
            <end position="2876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3289"/>
            <end position="3384"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2778"/>
            <end position="2805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1211"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1272"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1360"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1621"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1680"/>
            <end position="1693"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2014"/>
            <end position="2027"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2163"/>
            <end position="2177"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2191"/>
            <end position="2210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2253"/>
            <end position="2263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="3289"/>
            <end position="3298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="3304"/>
            <end position="3313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="3328"/>
            <end position="3338"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2454306.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="3384" mass="355403" checksum="37F03709AC4C54E0" modified="2021-09-29" version="1">MAARSEDSEGLVRIQGDFNAVPLSRSIRQEVLFFEPDIMVMELIDNSIDATLHRSEPHITIEVNLVPEPGGSELIFSDNGRGMDLNTLKNYFRLAWTTSRIPPLPRDEHPGVLPLQHFINPKLNRYGRGCAACLYFGNYVSVETFRANVGHAYLCKYDYGAQESTTNYELEMYQRTQWHIADDEDEMDGWTEIKISQLLPERLQELESAEFWNGLAKKLSQVYAFFIHGFPEDLWNRLPPELTVGQHRPKGGLEIQIKVTDHRGEQPRVVFTGALSRDASTGSSGGGPRPQAFVSDLQAVLREFEEQCRANPLLQPCVTISRYLPPGLPVPGERHAPSSSGVVYASGRVDGGAGRGARRSYVQPPAGLTTPGPPPTLPRGGSGAAVAAGNGPHHQQLPQGSVVGSVADSRLDPEAAGEVTVLVGDSGTDIETRPKDAPCDFVTIWLYFPYSQGLRTKPKRDNGKELFVFPFWSGKDMVNSKLHGQYLDTHKAAVKMAMANQAVQAHKHKLEDTGRLVALVLVSPDALAHQHKSDFEGRAYRMFCEAGPAADPYVPSGPDQPRLFTYIWPAEPERRNGAGNAAPVIDLIGDTPVPAKAATPSRRTSTAATPLHPLYQLAMGGLATVSAAGAVAASGRGGGARTPGTGRGRGPGGGGGGYGGRDAPILADYCGWREDKERGWAAVQLLQAFATWRQLDEDGQLVDSTMGELTNDPGMAPPWGFDVVERGFVEYSQKYTYGPGWEPLQAGEMVVVGDATKIQQRRVSAAPTAAAAAGGAGAGPAPASGRGAGGAAATAVAAGSGGGAPGARSGVQRRPESARIVELFYIKGSDYARDLFAVARKWRPRWSPKPPALSICIMEVQPILKENKDGTQLKARLKEKEALAAKWEDTLPSRVVAVQETQEGSRIKLPAVELETNHAFDSLTLALAKPQPAAPASADGAQGKKIKLGRPPGGGKAAAAAAASGAAASGGGAGGGGGGDEDLLLDASKLMYFSTMDNAYRPVVKLVIEREAPAGGGSGDAGGTGVWDEVFSREQEEPDKGRWKFSGFKKYIKDPGRYRLRVLVSEGVVAEDAPAATAGGAAAAARDPSRPPAHPNVNALLLLDRSCDPANLYGDYFTALEHRFVVSAGLPGALTAFFASSPELEQALAAGETITSSMTREAALQRPPVVRLGEPVPVLAVQLQDRKGAKMAFSTDLMAKLRLPWDPATPPSAASGAGDGAAASPGGAPARRPHPLKITAAVVGGDPLTLPLQLRPPGSGGGSNSSRAQENQQQQGQQGAGPSQPRAAAAAGAVAAAPGSGGSAIRFSEDRMTMFVSGLCFTPVELQQNVAGPDGRLQKGVTVSEIKARLNISLKVRTTAAASNPASAKQPSAGATGAGAGGSSSPGTAAVALTVRLPDNAPGTEVRLVSGPPAGLEPEEALLLAHDSLENAIKLSKGTHPAKDLALRLLDAHGNPYFLQAGGPRAALPRVQLACCRVGPGGAEGPSPVMVRKPGVAAGSTTSRGAKSEFTELAEYEFDISGNLLTLRGSDLRAVGLPGDVGRLTITLMDQGAPPLPAGQSAAALAAAARRAAAAADAAAQKAGCTSLELLARRKAPGGVRSFSVYVHIPEVVLGVEVAEDEEGAEQDADADVEADAAAGEAGPSSNGVEAPAAVGSKRKATPTPSSAATGGPARKAARKGTASSRSSASGSRPQELGRSAGRRRANAHVHEYTLDGTDTARSALRELLRKVLKLQRLDALTPLSWEQLQLPAPGGDDDDDDECTQKSLLDEAFERRLRYTCAGPQEVWLRPSGTLLLTRDAVLAAMNVALSPPPLPSAAAMAAATLPSAGPRVAGGGVTYEQVFVLRPGQLELGGLRLSLSDAEDDVVNELLSVSVRVFIGNRDAFKGGAVPLTVKSGRVDLMDLAFEPGDFAGPYRTAAVHVCDADSVSAVLRGSSVKGNARAAAAAAVSKAYRYGTFYVRQEPHPWELRLAPIDCPILTNHRAELLQSPPAAGTSSQSSMPAPVEGTLRLPASTPAGAAGAAASAEEERQPQLLELVCGSGTAAAARQRQGGSSQPERKHDAAVLLASGLSLARQRVSIRAGDALQVPLVVVDQHGMPLRVSPELAAQLEAHTRAELVPRAEAAASANAQAAGSAPAGAIPCHVHWSWGCAVEAQEEQAQEQQDAAGDQAQQQEQRQEAEGGPRRSSRSAASTSRSQPQAQQQAPQQQPKPLPPLPHFTAQVHLPQVQGAHALRLEFDAAAAAAAAGVAGAGAGPSTAPARPAPEPASGSTATMRPATLVFALDVTHGKLAPAGYRLGLSAPDGVQPEALEAHPAGRSESDMALLPAPECDRIFRVEVAEQTDLVLSVQLQDAQGCLVAEDGGFTLQHVHAGQLQEAPLTVRGGVLTLQLPVGAGPMWLSPPVATPDEAAGGEGGGGPATVGRLLVLRPTSDNFKHAQPLCIYLHVRAGRYPVEPLRLLSVGGRSGGDLLQLRLALSNSDPPPLDADANAPNADADEAALVPAAGAWPGLPGFKLQVLSADGVKFEAEELKDLKLHWERQADGVSERWEEVEDAPSAELMPRPSGVFAARRGGVPLPTRAGHWRLMAVYRDERVLSPTRQLQPVQVLQVHVAPAPPTAIQLSPQSEAALGSGAGRQQCRLLSWAELQQGAPVLPAMSGCLVDRWGNHSVPPPCSQPGAFAPTLRRILLIAYERPADSAAGGSVPAEVPMYHVAACEVCGQEGTFQLPAVSLAGQPLRMGWDYELYLQLADEQEPDRPGEVCELVRTLYVCSVADSAQLYEDVARLEAEISSAQAEVAACSANLRGAEYATGGAAQDLAEQRHRLAAALGRPLPPPEQLEAEVEAADAEAASVAAAAGAGAGNGQPPPAQQQPLRRLVAHEQAVAAAVSHLAEQEAELGRFFEPGTLVRYQSQQRYPHPQQQQQPQSLCLSPVLSRVGPNGAVDEAATRQYQRVRCIADATFGVPGALGPLVMLGAAERSDVSDALAYLSRGSLDKLYVVGRSALDTVKSQLRELGAGSALDLCNGSLERFYELDPGAVDMSHPQMPLFKREMRDRYRDVLNFDVPRSALEGRSRPQDAREPDDHGFIGFAVNLVHLPPHLADVRVPTSRGQATLRQTLLNRVFGHAMVFDTEANVTAFQRRCSERGLRIETPVIAVDGRGGLNLGGIGEEQFGRRTRMSIGYSGLPPELVTPLALAPAAAGQPQQHLRGGALDLRLRTEQVRTAMMGNRRAQLQALATEVSDALQRLRVRRGMEAARRQELAALQLEAQPRLEALQQELAAAQAELERVRQRERQQQPQAGAGGGAGGTGPLERRRSGGDESNGNGAGGGAGGQGRDQVRYGRRPTARQPRLEHAQQGAAGGGARKRAAVELGGKSVKRPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WYD6</accession>
    <name>A0A835WYD6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_000418</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC73 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454575.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WYD6"/>
    <dbReference type="OrthoDB" id="2186602at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016593">
        <property type="term" value="C:Cdc73/Paf1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000993">
        <property type="term" value="F:RNA polymerase II complex binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032968">
        <property type="term" value="P:positive regulation of transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006368">
        <property type="term" value="P:transcription elongation by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11990">
        <property type="entry name" value="RNA polymerase II accessory factor, Cdc73 C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007852">
        <property type="entry name" value="Cdc73/Parafibromin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031336">
        <property type="entry name" value="CDC73_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038103">
        <property type="entry name" value="CDC73_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032041">
        <property type="entry name" value="Cdc73_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466">
        <property type="entry name" value="CDC73 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12466:SF8">
        <property type="entry name" value="PARAFIBROMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05179">
        <property type="entry name" value="CDC73_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16050">
        <property type="entry name" value="CDC73_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="Paf1 complex subunit Cdc73 N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="domain" description="Cell division control protein 73 C-terminal" evidence="6">
        <location>
            <begin position="317"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="119"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="199"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="125"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="199"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010427"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF05179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF16050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2454575.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="484" mass="51416" checksum="2BFDE9771895BB52" modified="2021-09-29" version="1">MDPLSVLRDFNTSDRLHLVQQLDGNVQFGDRYAFPASTPVYKKAGASAYYTLHDVLFYLKNRQLKPQEYVMAASQAGLGIVNIMDRKKMLEVLDGLTVLDPSLVPVGVVVPLPQQRPAAAAAEEPQAKRQKVADDEASAMRGLMEQERQLRNRNTMLIAPHKDFRKVLEVVANAKKQAHKQAAAAAAAAKQTAAAKQTAAAKQPAAASRPGSQPQSQGAGASSSSRYGRDNTADQLKAMGAGGKGGIDMYGTSGSRAAAAAPAPPPAAAAGYVPVRKSGSSAAAPLPPSSSSKSGKSAPAAAAAAGKGKEAAKKGGVPIIIVPSGMTSLINMHNARSFLEEGLFVPTQQAIAASGGAPKQMQITIKRTAHRQSPVEYVVTDKPPAKDSPDWERVAAVVVQGAKWQFKDWPHKGAKDGDLVDALGKVCGFYVHFSDEKVGPPVSDWNVRTVPLHRESRHKDMTAMLELYRHLDVFLQAKRSPLAF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4B1</accession>
    <name>A0A836B4B1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Endonuclease/exonuclease/phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_008162</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000024">
        <property type="protein sequence ID" value="KAG2447008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4B1"/>
    <dbReference type="OrthoDB" id="428734at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.10.10">
        <property type="entry name" value="Endonuclease/exonuclease/phosphatase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050410">
        <property type="entry name" value="CCR4/nocturin_mRNA_transcr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036691">
        <property type="entry name" value="Endo/exonu/phosph_ase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005135">
        <property type="entry name" value="Endo/exonuclease/phosphatase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121">
        <property type="entry name" value="CARBON CATABOLITE REPRESSOR PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12121:SF100">
        <property type="entry name" value="POLY(A)-SPECIFIC RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03372">
        <property type="entry name" value="Exo_endo_phos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56219">
        <property type="entry name" value="DNase I-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Endonuclease/exonuclease/phosphatase" evidence="2">
        <location>
            <begin position="35"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="207"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="352"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="553"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="607"/>
            <end position="628"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="842"/>
            <end position="886"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="956"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1043"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1067"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="250"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="277"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4B8</accession>
    <name>A0A836B4B8_9CHLO</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">HYH02_008175</name>
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    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
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            <taxon>Chlorophyceae</taxon>
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            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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            <begin position="23"/>
            <end position="46"/>
        </location>
    </feature>
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            <begin position="66"/>
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        <source>
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    <sequence length="96" mass="10777" checksum="98495550BD0D279E" modified="2021-09-29" version="1">MQDLLQPEPDSRPRSQPLLQRRLAGLLMVLGAVGLVIGYTAHAVVVLAPPEHLPSFLDAMRKYSELIFRATFTFHVTALAALVHWFSRKLFKHNSA</sequence>
</entry>
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        </source>
    </evidence>
    <sequence length="3978" mass="392123" checksum="B94A3D99B7EBCED0" modified="2021-09-29" version="1">MHTKRAISLLAVWVLSATALGHSTRVALAQAGNTTVHVYQPPHAPDSQLGPVYGNRKSGWLAVGLLPEPISLTDAGISNTSAFDSAGRPLTCDGTTISGAAFSALALPQQQQRALDLALLVDFELQSPGAGQQHTGAAAASGSAAAGGLLRELVRVGGLRVQWDVVTGRILLGASWNPNATVAVAAPTTLVEGPQRVRLSISRRRSDAALAVCVNGGPARLLQAPPTVFPITPEAADGWLVGSAFGAAWALGPVEPLVAAAEQLGQGQGQGQAAAQPQPPPAGDEAVVLLGVVDSDGDAGFSASLPLSARVRQVWLATAAWGCGEAEAALSLSGPQSPAPGLASRPPAYANSAPELLSMDVQPEGGGTGAAGEAFVGQRVRVAAAVADADGDPLRLRLTFFGVPPSNCSTAECGNEVVTGEGAGRVDLSHAVAFQLPGRYVVRLEASDGSGAVAAWDAAVLVRKAGDAQRLAPCCRSTGMVIAGQDGRPVHSTRFRDPAVARLAAGLGWSAAYLQSQEELEAERLFDFGLLAPAHNPGGVRLRRCVDLFLAGPGSPRVLGGSERQRRITTGPNKRLLIVPQGFSWGEAAAAAGPASAPACESHWSQWAGSSPYRRSTGTQSDGSSPAYCSYACTRDGTQWLRSMAGLTDRLAEALAELSYGRLSLNAWAPVVTDTQLMPQNTSGYDAFSYSGAGLSEHLQRQLQLLDSSPAAAAAGSTPSSSSSSASSPSSPSSSLAAAPLSADASFSIANVSATSATTTPAPAYAAATASAALAARFHTTLVLSPQPPRSVNPGYTAWSAVGSGTAFVMRCAPQLYYMLHEIGHLLGLPHAGMWRLDNATRAPVDPAGAGGPVDDYSDKLDMMACCRGDFGALSRLWLGWLPYPERQHIPIFLLQKQQPQPTAPPAPSAPDAAAPPTGTAPTAGSGNGGSTGSTTAAAAACSPAASPQGCSYSLWPLDRAESRGRLKALTLRLGPGEAVVLSHKSLAWWQDARLARDGGEVPPPPPDRGSLTADESRLALGPGLSVEYMRLVADPSTGRPSWTPRGLLDMNLFFGEWPAALPRTPGALPPEPAKSAFALLREGQAWLHHLMGGSSSAAGGGSSNSNRNSSGSASNTDAAPAAPGLLVVVQREADCEEQPELPVHAYAVPNFYGFRGEAPGAEAWRRADYSGYSASRLRCLRVTVRTALPPAPVPAAEGGSGSGGPGKLRVRVMAVAPSTPPPGGRPDPNAAATTGEPVDVRGTCGFPLLPRLRLLVSASDSATASSDSSEGGRSGGTAETGGSSSSSRSSSSGGGGGGEGMPPFLAAAVWKDPLNITFAADTLTATLPPFSDGWVREAAAADSPTCAFGCDAAYRVRLVAWDGAQTLVTIRVVEVSLRHYLLHVSYRHYQLQRISTEAEVLYVPLLPPVAPLPAAPPPIPGRSGSTTFSASSSASSSAGSSASSGPQAWGLQLLGDAQGTQPLDGPAAVWQAAQLPPTACSRQWSLTLLLQVQVPAAAAGSGPASGRWHLASGLARSGGSPASAAPSGSATAAAAGPGWPSLWLVANGTGGAADSSGGRPALWLVTKLDPAREAAVPLRGGDAGMPPAAAAAAASSPSLGSRRTRHVALVYDNGRLGLWADGVGAWLWRDMACVPPRPGVTHCAGWPGLAAPATTATTSSSPAAGSASSDGGGLPSGLRLLGGASADDTASPAAAASVIAGSLLLSARMYNYALPRAEFGAEAVCLSASLQQQQQQGGPSSSSSSGVGAGAYSACARQFGLRTSADPAVAAPATAASAAASAVLPAAALSVVLPLTGTSGQPEWDPLLAAAAAVAQPQSGPSPAGAATPGSSTTASAQAQGAAPGSSGGTSSSSSSSSSSSSMPSILAWSYTLRVGAWSACSAPCGGGVAVRSVLCFRATPLGPWPVSPDDCAGSSSSTGVIGGGGAGTAALPAAVIACNVHPCPETRVELSRAPGPDPCAAAAAGPAASSTTQAGCQQQVQDSIRPTAVLLQPSCVAGGTLLVPLAACADSGADSNSYARSGAGGGVLLSAGDANRTMTLCNTTATSRVAPGSGSSSQQAAAGGWPLLLAEAAWSAVSLRKPAGSDSAGSTGGAGTSAGDTQAPALAEQQDVSTTTTTTTNTTAAAAAAAAAALSLQQALVSGQLQRQCAGSGDGGGGGGAAAGSAGGPPCSTPAGVATAPAVGPAQPQSGWRLEWRYGAWGACSGGCQGSRARKLSCANATTLVTSSGARNASSANGSAASSDSVSSTQAPMAACEAVLGLPPPQMLTQPCARGGPCAAPPPAAPGSASGGSGDSNGAASDGWAAAPVLVPLLSAWSDCQPSSSSVMGFGIRTRSLLSCVSVGGGSSPAGTVTGSCGAWHTRPEDAGPTKLPVTSGGSSSSNTGSSDSSSSRGSGGEWLVLATSAACVVPAPFQGLCQVPALARRGEAPCFGNGVCTYAGCACAPGFGGQLCEARLTPATATPTATAAVAARNSATSSALPRPSPASGFAATAAAGNDHCRSGVLDAQGQCCAAGVTAADGVCCGGADAAGAGGIVGLDGAGRCCVGAAVDACGVCGGSGVGVDVRGTCCSGLLDRYGVCCAAGRLLDECGVCGGDGTTCALRLQIRLSLRLSLSLSLDSGPDSGGNASPGGSGEGVSPALATAAAAASGPWWQPLSLAGQAAAGSGAPGAQNATAGAGSAAGSVVQQLPVALLPAASAALGRLLRLALGPAQAPLQLQLRSAVVAAAAAGGSGTDALRTATSMGDSRPQPTRHLLQAPGFPNSAQQTNEPQANRSAILRTEVLATYDILYGVGTDVNVPADSNSTGTFIPGGGVNEGPLAPYNFTTTAVALRLQALSAALAAASAAERAEAEAAAAALPPLPGLSGPAPDASPSPASAAGGVATIQAGGGGPLGVASGSAAAAPSSTGGAGGGGGGGGGSDSGKGDVWSSGGSEEFVGGGYFVVREQPAGGQQPQAQRGGDQQPQAHTEALGQGHSSPAQGHSTPTPAAQVHRHQTRRHRRRRLAQAVGVSGDTPAPPGAAPALPSASTPTPTNTNTNSTGVSAAAAAAAPAAAEPAAQLSPAAEAAAIAFGLLQLSGLQLAGLQRQGVCGNGVCEVGEKAAAFASVSALPASVSAYASGARSSAGGATAPWEPLAGGVSAGSGGDLYGEDECAADCPLQLRACPAGSRSGASGGAGPQLLQCSGRGVCLIASGACECFSGDGACVGQFVLGRTLPQWDLLGTGAAPPAPKSGLLRNPVALPLLVVGSVLAALVLVSAGVWLWRSGALASMRRSKRVAAADASPARAKALPSGLPRLTPPPSSARDHHHKPRHSPARAAQVVPYTPQRVAAAAAAAEALAAAAAAAAVGITPGGHTASPGQPGSRATSRNGWLSPGDPVAGLAPRRLFAGGECESSPESDARGGGTPGNRRLVGGYGSGGEGGGHGAGRGHRAVRRALLHVDATGSEWPSLQQRPEELQQPQQVFQQQQQPGLMHGGGLGSDVASAVAVAKAAGAPQVDELPTSSPHPHHIPQGQLPQPRHASPGPGPAAAAAAAAAAAAAAAPPRAVWFRAGPAQQPVPPVAGAANGPAAAPTAHPSPGRSPAPPAPPPSHPGSSYVMHSALPQSYSALPVPVPVPASSQPPQQQAPVAPIRPRVATASSMLSHRALTSAMPWLQHQHQHQHQHQHQHQHQHQQTPVRGGGVGGVGRPGGNPGGGAAGAGGRAIGEAVEARGHPREPTRATDALPVQPGAHALSHVRRSRQVPSRSVSHPHRPLSQPPHPPQLQPPLHPPLSLRDRPSAATDSTWALHGEALPQQHGAGSGAQALTSTTQARPNPVPATVPAPAVLLRSPSAATAGAGAEASQPAATTPCSLIRTPPATRTPGPSPGLAVASAAAGPGLAAAASTAFATSAAAAACGRPAAAPAAAGVTVTVAPSPRVAMLRGQHSNGSSCSSGGCGGGAGGGADDSAVVIKSPRSTPAVTRPVHMVGSRWAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B6C2</accession>
    <name>A0A836B6C2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005699</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2448941.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B6C2"/>
    <dbReference type="OrthoDB" id="552074at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1740.10">
        <property type="entry name" value="Zinc finger, PARP-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036957">
        <property type="entry name" value="Znf_PARP_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2448941.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="145" mass="15014" checksum="4D7EA9DF2B485D33" modified="2021-09-29" version="1">MTIYKFDYVPTARGCTCEGCRAKLEEGALRLEIMAGSASPAPASPHSSAGGGKKGAKSPAAKSTAAKSPPTKSAGGGREHSARYRCLDCITPTIAAHAVEAAGGEVEDLPGLPELRKHDQQAARRSAAGCVRWCRGLRVAVRRAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B7D4</accession>
    <name>A0A836B7D4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RmlD-like substrate binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005395</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B7D4"/>
    <dbReference type="OrthoDB" id="6235964at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029903">
        <property type="entry name" value="RmlD-like-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43242">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43242:SF1">
        <property type="entry name" value="NAD(P)-BINDING ROSSMANN-FOLD SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04321">
        <property type="entry name" value="RmlD_sub_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RmlD-like substrate binding" evidence="1">
        <location>
            <begin position="1"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF04321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="341" mass="36187" checksum="451582CB9C2DE3C4" modified="2021-09-29" version="1">MNVLITGGSGYLGQFLVHGLAGQGYTVHYAYGSRQLASAPPGVVAHKVDLATGEGLQEAFDQAPFHAVINCAAISQPAVCENSPDTARAVNVPSHLVDCLLRQEQVRAGLRAVLVHISTDQVYDGSRAHWKEDEAGGQVNVYGRTKYEAETHILSRLPEPYPVAILRSSIIYGPPAPDPVPRPLFLQFVASAVSNPDKPTSFFQDEYRSPVHVRDLQRITELLIAAHGQQLASEAAAAAAAARGGGQAAEAAAVPARALEALAPEALAAVAARRHRVFNAGGPERLSRVDMARQVADCLGCGYDSIESVPSASVARWVQRVFGGRGRGGRCRSLTCTLRAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B7E5</accession>
    <name>A0A836B7E5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_005193</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449663.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016592">
        <property type="term" value="C:mediator complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051647">
        <property type="entry name" value="Mediator_comp_sub12"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46007:SF8">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46007">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52058">
        <property type="entry name" value="L domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032816042" description="Guanylate cyclase domain-containing protein" evidence="4">
        <location>
            <begin position="17"/>
            <end position="3929"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="407"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="594"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="5">
        <location>
            <begin position="3100"/>
            <end position="3239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="913"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1172"/>
            <end position="1230"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1363"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1450"/>
            <end position="1469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1532"/>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="2">
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    <feature type="region of interest" description="Disordered" evidence="2">
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    <feature type="region of interest" description="Disordered" evidence="2">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="2820"/>
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    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="2926"/>
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    </feature>
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            <begin position="3852"/>
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        <location>
            <begin position="980"/>
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    </feature>
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            <begin position="1012"/>
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    </feature>
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            <begin position="1966"/>
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            <begin position="1986"/>
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    </feature>
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    </feature>
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            <begin position="3371"/>
            <end position="3383"/>
        </location>
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            <begin position="3571"/>
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        </location>
    </feature>
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        <location>
            <begin position="3642"/>
            <end position="3653"/>
        </location>
    </feature>
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            <begin position="3702"/>
            <end position="3714"/>
        </location>
    </feature>
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        <location>
            <begin position="3715"/>
            <end position="3740"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2449663.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="3929" mass="383638" checksum="5EF21E2A85B44FAD" modified="2021-09-29" version="1">MGLLLLVLVLLSTTAAQQPSDSARLILMDLFNATGGPNWSQLQSSIPASGWGAGSDPCQWTGVICCSPGTGLAGQANLTYTYARRRAGDAQVVVTRPCGTAGAVVGLALPGANLTGSLPASLAELSLLEVLLLPDNPGLHGALPAALWALERLFEMDIRNTSMVCKDLGSGSGSGGSSSSSNGYSSGNSSAAALLSACTVPVPLLPSRTTMVFTSSPGADVTLPVLPPGTSYACPLLHYYRNALSGLATGASSASSNTSNTTVAAAYAVAALVPAGGSSTTTAIAGASASSTGTSDSAGGLVAAAAAALVLDQDGVPSGAAVVRADPRYWLYQSCACLQLPGAVATAARQPSLLLLPSGVNATAAGGVAASCAAAAAVAVTANGTDSGSDGSSGVGDKSSGEVSLSVGALVGMVVGIAVGAAVLTACCGAAGLVCYASLRARRQRAAAGSRSRNSSAKSLRSRALGGGAGAGGGAGGGVGGGAMHGGAQHGSWPVWWSTLAEWLWDSDGQGGSGAEWVGAAGAGGAGSMSQSSRQLTAAGQHQLLLTGVSGGVGSGLPGELPGPSRKPMPGSLFEAKRARPPGCHSELFGHEVTLVATDVEGSTELWEWQPDVMNAALALHDRTVRLTLAACCGYEVTTEGDAFLVAFHEPVDAVRWALLLQSALLKLDWPPLLLEHPLCRPRPLVPVAAPGPGPGKDGAGRDAPLLVLFKGLAVRMGIATGVPSAVREHPVTRRMQYTGAVLRLATGIAELGCGGQVLLEPMTFKGIHNKFEELDVEESEVQELTDLISGQPWEGEEAGGGRASRSVHLAPAALQLQHQQLSQHLQQLQPSLGARESLVMSDHFAGRYSPAGAAGPGSATGGAGLSGYASGPGIPSGSAGLGSAGGGGTAGVAGIGGAAAATGGGGGPGSTIGLSTARSAPGSAAEGDYFSTAASSPALYPPPQGHAPQGLQPAHPHPHPHPHLQPPHHPQHNLPYHYPAHHPQHHQQPHAYAHHHPQHNPHHAPHPQQHGQLHTQSYTHLQPHHVPRSSRDPSSIAPVAATGTATGTAGGPPVHRGRSAIMLGQEDAAFGLPPGAARTQHSIPTQHSNLVLALAGQPGVSVGAGTGVGHVDGGSSLVSPPQAPMLALHPTGSSSVMSPGLALIERSAWEAAAAAVPNAMAALAAAAAAAAGPPGVGRTSGSRLSGGRRNSGNRASGGDTASRGLGRLQGLGYTTSSTSNGGGGGGLPLFSAPLPSSMVDGLHSPPSPSAGSAGKLPLLVQGAAASQVLHVRRGSGGGAVIPPGIPRSGGTSSAGGFMPAGAAAASANGGGATSSVGFSLAMGSSVGVYAGLGPASSITPPSPTAPYIQQIVQQLQIQNQNQALVQQHPQSQPEQRAQQHAAQSAVRQESSGQAPGQGQGQGQAAAHREGHAVAPSTSGVAASSTHVAVSAAFQNHFLSTQDLVSSVGGGGGGMSGLSSERSSSVAPSRRVTAAGAALALAAGPGIGQGVPGTGAGGMEPGVAAAGVPSAAGEWEQGDAVGGVTIEGYVMPALSPPHLPRPPPPPRPPPAAPPPPALQPASAQSPMSKLSARGPSTVAVVSLAAGPLCEGRELDPRLPNSSPDGYLDPALVAAVAVAGAAAAEAEAAAMGAAAGTRDGATTPGSATPPSHQLLQLQAQPPCSPSPGSTGITIATTSPGPHQLLHQQHHHQQSLTAAAPLPPAPIVPSGGARTTPFGAVVQMAAERSFRRSPAAGGGPPQLHRLASMSNAGGGAATGPRGSATTSGAAPSGLISAAAPQGSGSGSLGDGAIAGLSNGGSAVASSSTIGTGTGTTAALSMLNPLSAAGAQHYVPAAGSAAAAAAASASAGPAGDGGGGAGRLALPMHNRSTGHLELSAHSWEAGLLSPDGAAERAASQPPPVDESARLLDGGGGAGAPAEFRLSLFTAARVCTSSNSVSGAPLSVLSADPVTPPSQPLRQQPPPGEKGSGGSAGGAGSSDALNASGPSPSSPIRTSLSLAVSGRANARRAGDPSYGGGGGTSVTLQAALSPRHPDALDAGVYLGASGGSSTGSYYPPAALAGALASGGSVGGIWLGGGGGGGGGGSGSGGVGLPPDQSGTAWHQPGRHTAPQVLEAGAAGPGCAPMHTPPVAPLPAAPHLPGYHSWQVQAQAQAAYHQHVHSLQQQQNQVQQQNQAPVPLLVPHMLPTPADHGGGGGGVGSALESPRLVSPRHQHNHHVMHMYAFPAAAAAHPAQAEAAVSPAAPSAAAGAGAVLGRGSMSGLVGWPRGPGLAGALLARHGGGGGGGEDALLRSATAMDGFQAAEVGRAGVGVPWRRSSDPDNGAAAAADVAVSDTAAAAAAAAAAGGGGGRTLGPAGGGVAAGGGGGMAAHLDRNLRNHSMRNLMDLMNMAAAGPGGGHPGLGGGHAGGGGGTTGLYDSFGSGGGTGGTGQGPRLLALRSTMALQAAGSNANRAAKEALDLSMGMDSDYVDPISPRAGAAAAAAAPAQPPQRAGAPPSVPQSGRSSTTGSSRFRAPRKNSTRSLLLDLLRVPSLGGRSSGVQPQSGLAPTPQLAEQPLQPQPSMKLQQQQQLHGAAQPGNAASAAAVAAAAAAAAAGRPPPSWGPGMAAISPAALVGAGGTVHQGLSSQLAISQSLLPPTSPSSQQRLSIYSAPGGASGDPESRRMQHFSKSPITPMLGGGGGGGGGVDEGGSVRGGVSGSAAGPLMTFEAVGQGLGLDPLACVAEEGQSGPMGSGSRGGGGSGAGGAAGGVEGEPRGGHGGLPSGIIGVTVGGGDTTHESGHLLQAVQAPAGAAAAASGGAAGAQRTGLLQAVGGAGSAASDAAATPGPHPAAATPGPHPAAATPGPHPAAAAVAAAAPPAAAAAAAAAAAVSAVAAKLELATAYGSNNGVGAADSPRTEVQKLKERYTKRSFIKSLSTRRRNAATAAAAVGAGGPPSDREPRSPSARLRLRGTAAGLLGGGSSKDGGATSGSVGGAAAAAASGGLTSGVVSRRQLQAQNTTASSLRSPLAAADRHSVVVVDMGTHQLKIPALGAAYNDIYDGVQVIQILPEHLKYRAAYNPPLKSLAQLSPSFFDAPGARQALTPMSPGQPPSFPRCSLLFIQPAGYSAVANSHPEVAERSGAVFSAAVREVLSVFSAYECQEYENTFMVACHGPRVAAEVALALHSWLLDADWPTELLVDHAEGRVQLAEDGQPVLRGFRAKVGIFTGVPLSVVPHATTGRADYFGALVNRAARLMAGAKGGQTLLDKSAGLEVLKEWRHLAATHQKHLQQQQHLQQQLALQQLHSQAAHSQALLLGHAATAPLSPQLQPSQRSLLTPGSPWSAMVFAAASRSTTAGMDVGLPSPPVFARQSAAAAVTATAAAAASQPGQLPLAPQGLPSMPSLVQPHSHQQPHLPSNQQPPSAAAITAAYAAAAAAARPHLTRFGSSQTRTPGSAPSNSPALVALVAALSVPPAHSLPSSFRASSGRSSAPALSSSPPAALGPLPGSWVLPVGAVEAVGGASRQASQPAVEVVHDSATDAALAAAEAAADVAYAAVAAAAAAGSVPLELDPAMAGAARAIPPSPTGQPALQPHPLAAAADPHAREAGGGNSAGDLTPHFAVAAAVLGFGEAADASEDAQRAVDPQLPPAPQPAAPSGRSHNTSPANSANMLALPPPPQQQQQQQPEQRDSDQQLQQLQALDHAGDTLRTAPPRGFSPGPSPGPSPGPPPGLSISAAPPLQLPAASGPQPLGLPSLGQPPLVAGGAAPSFVTSTAGIGSAGGGAGGGGGGQAGSGAPSAFQLDSVGAGAPADWWTALQASRNPQLLGRVHCADMMVQVCDLGLFKLKGLAEGQPVIAVQLKRLAAPGSCCASGPPAAPGPTGPGQQQQQQQGGLGMAAAGGAGALGASKAEQLRGTALGLIDEVLVSLPARARPHEGTTTTTSVGM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B7F6</accession>
    <name>A0A836B7F6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CBF1-interacting co-repressor CIR N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_000023</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000012">
        <property type="protein sequence ID" value="KAG2449917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B7F6"/>
    <dbReference type="OrthoDB" id="2159131at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039875">
        <property type="entry name" value="LENG1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22093">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER LRC MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22093:SF0">
        <property type="entry name" value="LEUKOCYTE RECEPTOR CLUSTER MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="139"/>
        </location>
    </feature>
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        <location>
            <begin position="156"/>
            <end position="373"/>
        </location>
    </feature>
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        <location>
            <begin position="27"/>
            <end position="53"/>
        </location>
    </feature>
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            <begin position="95"/>
            <end position="131"/>
        </location>
    </feature>
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            <begin position="174"/>
            <end position="211"/>
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    </feature>
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            <begin position="234"/>
            <end position="280"/>
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            <begin position="286"/>
            <end position="317"/>
        </location>
    </feature>
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            <begin position="318"/>
            <end position="343"/>
        </location>
    </feature>
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        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="405" mass="43294" checksum="AB768677F3D86160" modified="2021-09-29" version="1">MGGHGGLNILPQKRWNVYNRDNRLKVAQDEAKAQAKEDEARERHEQAEREHRHALLLRRAGGGAPAAAGNGDAEGTTAIAVAQEAAGGAGSEGGQAEKKHEHINFWKEEETKLQNPENEKEQREAAKRRGNPDFYTSDAKFDERFALGYGIIGGDKPWYAQPLKPEPREPASTSGAGALNALPAGAAAAGSLPGTSGRQPQQQLQLQAAPASRHDREERKRKGKRRHHSPPPGTSSSSSSSDYTSDSSSDTGDSSTSYSSSSTSSSSANSSSSSDSGSGSEAEERRRRRKSGRRSRSGSRKRDGKSRSSSKHKRGKDKSRDRSRDGKDGSSRRRRSSRDGKDRRSSKKRRRSDGGALAVAVGGGGGGGGSKSLEQLRAERLAREQAERAKQRGVLAALPGALPDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B8F0</accession>
    <name>A0A836B8F0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Peptidase S1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_004815</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B8F0"/>
    <dbReference type="OrthoDB" id="542443at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2450309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="218" mass="22833" checksum="70DC26510F6780C6" modified="2021-09-29" version="1">MAFLLQRSAGEADVPATIRARARHSDKYAAHLVVEPPNSSPYKEAATVIGRHHVATFAHGGHEEWMLGQHLQIAVHCPDAPRRMFVDGKVVYKNPTKDVAILEVQHELPPPELDFGVVAGDKYYVHGQSTHAQPDGTSISHGVVAVTVPDACDHIRGDIVPGAGDSGGGCFSVHTGKLVAMVVGVDPRALKAVLVPAAILRGILTDLSATSGAAGAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B9H5</accession>
    <name>A0A836B9H5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">ATP-dependent DNA helicase</fullName>
            <ecNumber evidence="7">5.6.2.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_003556</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>Couples ATP hydrolysis with the unwinding of duplex DNA by translocating in the 3'-5' direction.</text>
            <dbReference type="EC" id="5.6.2.4"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the helicase family. RecQ subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.6.2.4" evidence="7"/>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451777.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B9H5"/>
    <dbReference type="OrthoDB" id="10261556at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043138">
        <property type="term" value="F:3'-5' DNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009378">
        <property type="term" value="F:four-way junction helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd17920">
        <property type="entry name" value="DEXHc_RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001389">
        <property type="entry name" value="ATP-dependent DNA helicase RecQ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.10">
        <property type="entry name" value="Winged helix-like DNA-binding domain superfamily/Winged helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004589">
        <property type="entry name" value="DNA_helicase_ATP-dep_RecQ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032284">
        <property type="entry name" value="RecQ_Zn-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036388">
        <property type="entry name" value="WH-like_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00614">
        <property type="entry name" value="recQ_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710:SF155">
        <property type="entry name" value="ATP-DEPENDENT DNA HELICASE Q-LIKE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13710">
        <property type="entry name" value="DNA HELICASE RECQ FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16124">
        <property type="entry name" value="RecQ_Zn_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="51"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="263"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="400"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="454"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="592"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="862"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="400"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="460"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="471"/>
            <end position="489"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="496"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="595"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="862"/>
            <end position="880"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005446"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU364117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2451777.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="960" mass="96523" checksum="2FB0FF470078B82E" modified="2021-09-29" version="1">MSKRSLSFSPTEHDSIAKRPNVRENNRQKALCLLKKYYGFDAFRGKQEDAVLSAMAGQDALVIMPTGGGKTLCYVIPALAQPGLAVVVSPLLALMQDQVNNLKAVGVPAAQLSSALPAAQREAILTDLGGGGGGGGEGGSGMSAPSLKLLLVTPELLAASKKFRYVLRRLHSARLVSLFAIDESHCISTWGHDFRPAYRQLGSLRSDYPGVPIMALTATAASQVQDDICKQLRLQSPLRLCASFNRPNISYSVRYLDVEGAGEAEALVRLLTERRRAAGGVLPCSIVYATKRDTCEDVAARLCRDGLAAAAYHGQMGDAKKREVLAKWQADEVPVVVATIAFGMGIDKAGVRLVVHLNLPSSLEGFYQEAGRAGRDGAPAESVLFYSREARRRMDYVLEKEQEKAAREGGAKGPKGPGGGAAADDSSAGGGFVTAAAAARAAAVAAVAAVKAGEGGAGGANSSPTAAAGAGAKGAGGHGVDSGRSGGGSGDDDDSPSAASAAAGPSAAEDAAVKKTAWQAFGRVVDWALAPRCRRRALLAHFGEALQPAGAPCAGTGNGEAAGCDVCRDREAVLAALEALKQQELAAAAQRQAGGWWGKGGGGGGKKGGDDEEADMFAVRGGGGGGGDDDGGGGQRADKDEGPGVYNAGRHDEVPVSAATASAARAAAAAARSAAGGQVNSAYFDALEAREREHERRQQRGGGDIVDRMLSAVGGGGGGGGASAAAVAAPPPDEGARANARNKLAGALAGNVACAGLEPDLLQRLAAAVEAEVYGNGHVPRQQYTSRMAGLLSRARAAPSALALLPQAPPAAAAAEGSPAGSGASGGGAVVAALSAAAAAPLLPALLQGEVAAVEAVMQPAASPADSPAQPQARAPAPLDRPTKDRLLGRLRCLAAVAVGVEAVAAGGVGRRLAALGKLGKQQAGSGGVGPGPGPEVVELADAARGVVAAWKRQLPERAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B9I0</accession>
    <name>A0A836B9I0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_003570</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B9I0"/>
    <dbReference type="OrthoDB" id="9675250at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2451792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="271" mass="28356" checksum="4721DB82D0C922B0" modified="2021-09-29" version="1">MASQRVRGLDWRNAYPFPVLTLPACRYDSDNWFLLHLPREGPARSWRLLDWEKNKGGARCSDTWLYPAATAAEGGLAAAPVAAVAAAGESGGNGGGRPGAAAGGAGGGGPGPGPAPAGYEAFAPHPMDPQPPETGSCGTPRLEEVGAYELEPLQAAGDVPGPSGHQFNPEPPCCLTFQRAFLERCLQEGPTAACCAILGEHLRPSSAAYGASCMCWPPFWSQAQDVFRESGRNASEVLERCAREHGKALQWPGRVGGSCLQPGSRQLPPLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B9I2</accession>
    <name>A0A836B9I2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_004178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AB hydrolase superfamily. ABHD14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451583.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B9I2"/>
    <dbReference type="OrthoDB" id="284184at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46197:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46197">
        <property type="entry name" value="PROTEIN ABHD14B-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="7"/>
            <end position="130"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2451583.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="169" mass="18675" checksum="F5D939ED65E80B8C" modified="2021-09-29" version="1">MRNPTAIFLHGAKYNSDFWLKLGTLKMVAEAGVRAMAIDLPGYGDTPALPYSDNNMRSELVRTVVEAAWARVNATVVLVSPSMSGRYSIPFLDRHGVMLTSYVAVAPIGVRDWGGPWEDTHKRVRGGPWEDTHKRVCALAVYGSKDALVPDAERLTKLFQNSWKAAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BAX1</accession>
    <name>A0A836BAX1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_002387</name>
        <name evidence="2" type="ORF">HYH02_002388</name>
    </gene>
    <organism evidence="1 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453053.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BAX1"/>
    <dbReference type="OrthoDB" id="17255at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2453052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2453053.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="73" mass="8019" checksum="9600EBF08F830030" modified="2021-09-29" version="1">MQFHHKAQGTPPYRVAAARRTGKVLGWNAKQKPWTHAVFFGWNVVSRTPGLLSVGDVLTPVSQQQPADMVPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BAZ9</accession>
    <name>A0A836BAZ9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_002455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BAZ9"/>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046404">
        <property type="term" value="F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046403">
        <property type="term" value="F:polynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006551">
        <property type="entry name" value="Polynucleotide_phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01664">
        <property type="entry name" value="DNA-3'-Pase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2453126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="258" mass="28143" checksum="3E161E38C90A3CDA" modified="2021-09-29" version="1">MSGRPRRAPKRSKKYDDEVDDFSDADSDVPLSDSDSDRKPRKKAAAAARGKKSLDAFTTDEGWSFEPPSIFYKEYGDAQPGDKIAAFDLDGTLVNTKSGATFAKDDLDWKWYNKSAPEKIQAYADEGYKIVVFTNQGTIKSAVKGKAAEKILARIDSIMEELGVPVQVFACTMDDHYRKPERGMWDFFVSRFNGGVAPDHAKSFFVGDAAGRTADFADTDKGFAENVGIGFRTPEEEFGQADGGKKAAAKKGGGDVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BB93</accession>
    <name>A0A836BB93_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Crossover junction endonuclease MUS81-like HHH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_002455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BB93"/>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.110">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027421">
        <property type="entry name" value="DNA_pol_lamdba_lyase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010996">
        <property type="entry name" value="HHH_MUS81"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14716">
        <property type="entry name" value="HHH_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47802">
        <property type="entry name" value="DNA polymerase beta, N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Crossover junction endonuclease MUS81-like HHH" evidence="1">
        <location>
            <begin position="18"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF14716"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2453128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="126" mass="13138" checksum="647DE8CDC9AF9B7B" modified="2021-09-29" version="1">MTTRSHATAWPHGVAVPENQALVDVFDELAQKAFEGSKTDPKAKFKGIALKKAGKALAEFPSQITLANLKEVSSLPGVGKGSIAKIKEFLETGTVVELSGVDDLAGVGKAAPQAADPGKDMAMNFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BBZ1</accession>
    <name>A0A836BBZ1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">P-type ATPase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_001535</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BBZ1"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032630">
        <property type="entry name" value="P_typ_ATPase_c"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16212">
        <property type="entry name" value="PhoLip_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="44"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="71"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="118"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="151"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="187"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase C-terminal" evidence="6">
        <location>
            <begin position="4"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="364"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="515"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="554"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="390"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="402"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="605"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="618"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="641"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="679"/>
            <end position="691"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF16212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2453309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="691" mass="70446" checksum="6D3F5CDBA960B678" modified="2021-09-29" version="1">MQAVMSADFAIAQFRFLLPLLLVHGQYSYKRISRMINFFFYKNMLFAITLFTYSAFTTFSGSYIYNDTSMTLFNVVFTSATPLLVGMFDRPLGKRAMLRYPQLYRQGIANRDFNTPTILGWMCSALLQSGIILVFSLVGCRGTTASADHGIPWSMAEVGVVMFTAIVLTIHLHLSMVEEAWTWLHHLAIWGSVALWYLYLLAFAYFPVSWSLEMWHLFGDIVAPNAQFWLYSLIIPAAALLPDLAFRAFKRLLWPSDEDIIREMQKAERAANIGSSHHAGGAAGGVGATSEHHALQKHKGGGGLMMMASLGSGSNRVAPEPLLSPPRGRQGNGVKSSAAIAVAEGGPGNRSNTVTAVIATGGAAAGAGAQDGGKAKGARGRRSSATREDGIEELDVADVADDVAAPQPASVAPRHSAAGALVGARSSREGTPNGFRLVSNKGPAGAAVQPAGGGATHATSRVGPSPFAAAPPPPPHGTTGASGGPDELLLLSEDGGGIDDAAGGVGRGESPLLGSFAPSPTRGLAAPTVGPSGIAGRSRTVGLPTVSSATSLASAAAGGGVPSGSGQHSQQHHHTHVPHGALASSISTPVLGEDAGRNSSWTGRGATGVGTAAGAGTGLSATASPRTQAAAARSQAAAMGSRGGGGGGGDPNASMSGGRMVLGQPSGQTGDGSGVREVSALSRASSASAQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BDB1</accession>
    <name>A0A836BDB1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thioredoxin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_000426</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BDB1"/>
    <dbReference type="OrthoDB" id="72053at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030134">
        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd02961">
        <property type="entry name" value="PDI_a_family"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000174">
        <property type="entry name" value="Protein disulfide-isomerase 5-4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045888">
        <property type="entry name" value="Erv"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012936">
        <property type="entry name" value="Erv_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039542">
        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF37">
        <property type="entry name" value="PROTEIN DISULFIDE-ISOMERASE 5-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00085">
        <property type="entry name" value="Thioredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="21"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="433"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="domain" description="Thioredoxin" evidence="7">
        <location>
            <begin position="144"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2454584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="474" mass="53403" checksum="7FAC77153FD7E6FF" modified="2021-09-29" version="1">MARLFSKLKAIDFFKKIPSDLTEATLTGAWLSIVAAVLMMFLFVAELTAFLSTSTSSQLVVDRSPQNELLKLNFNISFPALSCEFATVDVSDSLGTKRMNLTKTVRKVPITLDLERHGAAVEDTAHKMGPKYDEEGRFDEEPDIDITVPLSHANFEATLGRYPIVVINFYAPWCHWCQRLEPTWEASTKEVHDKYPEWDGRIRFAKVDCTAEVDLCRQHFIQGFPSIRVFRKGHDDIYIGGMHEHEAYMGDRTKEALVAFADSLVPSAGQPHRKLAGLSAAPKTPGCNLAGFVMVKKVPGTVHFVARSEGHSFDHTWMNMTHMIHSFHVGTRPSPRKYQQLKRLHPAGLTADWADKLHDQMFVSEHTQSTHEHYLQVVLTTIAPRHSRHTGNYDAYEYTAHSHSYQSDSIPSARFTYDLSPIQILVQETGKPWYQFLTTSCAIIGGVFTVAGILDALLYQSFKVVKKMNLGKQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SAG5</accession>
    <name>A0A835SAG5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_015549</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000415">
        <property type="protein sequence ID" value="KAG2421996.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SAG5"/>
    <dbReference type="OrthoDB" id="547029at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <feature type="non-terminal residue" evidence="1">
        <location>
            <position position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2421996.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="173" mass="19372" checksum="6ECD923EE8DD78AA" modified="2021-09-29" version="1" fragment="single">MLQEMRLRRGDAPYGHTQQLSVYWPPYVRVSRAHRMAAQRLTPPLAAGPAVWRRLTQERVARAPPAAWPRPEHTAAAAGERLFWAQVALRPSYLTAKNAPMVQVFKELGPITATAASPNGALLAVGTAPGVMLVFDMRGRPAAPWFQVMADGQTYKRPWWFRRRKPRNPAIVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SCL6</accession>
    <name>A0A835SCL6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_015166</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000123">
        <property type="protein sequence ID" value="KAG2424494.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2096344at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050349">
        <property type="entry name" value="WD_LIS1/nudF_dynein_reg"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44129">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN POP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1160"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1203"/>
            <end position="1245"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1478"/>
            <end position="1494"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1992"/>
            <end position="2026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="303"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="355"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="529"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="880"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1584"/>
            <end position="1612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="307"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="355"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="375"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="551"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="892"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1584"/>
            <end position="1598"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2424494.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2087" mass="208700" checksum="02E57E3815F834F7" modified="2021-09-29" version="1">MGGDQEQVPVIAAVAAGASAVQLGPGPPGTSAPAVGSAVEETAAAAVGSFPSQCTSEAVSRDEDPLATVSKGVSLRGLRRLAQHIAAWFGPVRYPHATTTDVTSQWVVGVSAPHKCRVAEMRSLLPEEDVGVPLYFISHAWKNRFQDLVLAVERHLAAAGEETRVWLDIFAVNQHGDTHFQPRDVGAFKDVVRASEGGTVVIMGDVAVANPATRAWCIYEWAATLALHGPDGLHIDLDAAHRAAVVRQLDVEAAQCFKPEDKDFILGDVVAQHGSTAAFNARLKLQLALEPLGGQAAEAERLMMGPQQQQQQQQQQQQQQQQQQAHAGGGGGADDQDGGACWDWAPVQQWLTDAAAAGQAQQPVGTTAGADDDGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGSAATQCAPSRLLLVLGGPGEGKSTALAAMAATEGPLQQQQQQPGGPLQAGAGGRCVGGAAAAAAVAVHYVRYDDARSRDPVRLIKTLAFQLAARLPAVLEALLALDPADITRLGGGGGGGAAQGEHESGSGAGPIQAAAGTPDAGAAWSDEQQMQAQVEVAFQLLLQQPLMAYAAAVVAQEQPQPPRGSALPVVLVIDGVDEADPPAPAASQGSHQPPTATPWVAGNPVLRLLTAQLSRLPPGLVRLVVSSRPEAAAGQLLGSLVRAFGPVASVAAATAPAGAAAVGVPGAPAGGGAVGGVLAGVTVLSPAQLRRTSGPHAAAAAGAAGGQLQGEVVACSHVAAMCGRLGLKTPPPQLLAAQAPDAAAGSGTAVPAPPHGTTVTSLSSLHAMYDLLLAAAVMTPPPTGAVDKQGVRGDAATRATVPRLLSVLLAAQEPLTQATLQSLGLGSPQLLGMLLPGTAAGAGGNAGGRSDDLTATSTSSESSTVISHSSTSGGLFYVSEHTVRLYHRTLADYLTGSWGPGGGGRSSIAGAGVGVGAGAGVDVGLGHWLLAQHLAAPASRAAPSPYALKYTAHHLAAAVNAAAATAADAAAVPALQAAAAVAQAQLRERCGLLDEALGDWTYLAAVFRAGHGPRLVAALGALTPAALAASRLARDSLFWLRAAVHSGAAGSGPLFGLGSREERLGAGAEALARSALLTAPLGSPLTSLARRVLAGRLGGWAAAGVAPWAPPHSDWEALGLRLKGHRGEVWGLAWSPDGRQLASGGGEDGCVRVWDVNTGACVAVLHGHGAGVRSVAWSPGAGRLLASCSRDGSVRLWDSATGDTAVVLLAGDVSALAWAPLQQQDQHQHPQQQRQEQRLVLATAGFTSTPQQGVFLWDGGSGACLGLLASVTGAAAMDVAWAPPSAADANIYVGGLKVAASCSDGSVQCWDAGSGQCIWCTLGAAGAGGSGGRLCWGPVGTQLLLVSCGERVRLLDGARGTALGEMGGIAPTGSHMMQMQPDLGAAGGGDGSLALPQGAGLPRGHTASIMGMACWAAGAEVGRQGQQQEQQQVPKQQVVMVATGGLDRTVRLWELRLPRAPPAPAEGQQPEPLLAQDAGCCVAVVRGLTGYVTCVAAQPYAAAAAAAAAAGHTQHQIQQLQQQQFVFSCSDGSVQLVDAVALQAEQQQQQQQQAPDDQPASAPPSSGPAAAPAAPAVWSPDGSYIASACVGGGLAMWRLGAADSNQQCEDAQVSGCHHVISLPLTPEPLQQLPSDCNADYGAGDMWGGGGGGPASCGRVTGLDWSAAGVLVAITEAADHGSGCGVCAITGLPGAHGCSSAHAQPRVQWLELSGGCPPAPCVSCCLTHLGCGEEPASCTVLVALGGGDGLGIRLLALTPAGDSSRELGCLQLPHPRDGEGVTSSVSAEAAAPPLAMAPPPHLSDWAAPPSLGDSGAPLSAAVTRVAWCASTTATASGGGPTRLLAAAYADNQVRLWAVDPGAGSSHSQQCVQVLHQDNPMAPVACCSVSCLAVSPCGQWLATNFQPSQQQQQKSGGGQVLVWRVAAQQGGISTGHDSSPFAKSDGGPVLVLTTGVTVGNGAALALDWSPCGRWLAAGCEDRAVRVWSLSWGQGGVRPEVTAGPLVVLEGHRHSVEVVAWRRARVGGGNANVSWLLSCGADRAIRVWRHGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SEM3</accession>
    <name>A0A835SEM3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_015224</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the OXA1/ALB3/YidC (TC 2.A.9.2) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000128">
        <property type="protein sequence ID" value="KAG2424141.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SEM3"/>
    <dbReference type="OrthoDB" id="2148490at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032977">
        <property type="term" value="F:membrane insertase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032979">
        <property type="term" value="P:protein insertion into mitochondrial inner membrane from matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001708">
        <property type="entry name" value="YidC/ALB3/OXA1/COX18"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428:SF65">
        <property type="entry name" value="CYTOCHROME C OXIDASE ASSEMBLY PROTEIN COX18, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12428">
        <property type="entry name" value="OXA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50005">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0802">TPR repeat</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="878"/>
            <end position="904"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="910"/>
            <end position="933"/>
        </location>
    </feature>
    <feature type="repeat" description="TPR" evidence="6">
        <location>
            <begin position="675"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="63"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="122"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="313"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="838"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="64"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="134"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="324"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="841"/>
            <end position="858"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010583"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00339"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2424141.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="966" mass="94897" checksum="C72F7DC717F47A8E" modified="2021-09-29" version="1">MRRVLSGFLGSTLQASAASHPAAVGSCKGAPAACLQLATEALLGAPGPLSSVPCSGIGRDRTPGNSIGCSDSSGSSSNGSSSGSGDWGRSGASGQLPPLHSNTLHDITAASHLHAAALSLGDGSGSSVPRSEPGQYSSSSLYTHTPREAPPAPPHALTRPALRTSAALAAAAATATAAATAAAAASLSPLSSTASIPLSASAFDATAAAFASSSASAMAASASVSSFAAASPGEPSLALAAVQQLANGYEALHAGSGLPWAAVIPAVTLALRLALLPLSMRQARIIRTNYSLYKEALTLTAAQEAEAAAAAQLAEGEAGRQQRHATWQVQGHGQAQEAGSVPGAGGGGGDGAAGALVGPSPGSAAASAVEKKEADLRAKLLRSQAVLSNFHLLRAKVGAPHPGWLVVNPLVQVPLFVGVSTTLGIMCRLPWPGLESEGLLWFPNLTLPAMVFPADGPFGAAGFVDASSPAYAAATAAAAEAAAAATEAATAYASAGVGGFPGVGATADLVAAATAANEVLLPMGTNGLLLPLIVYGMTMSSLRLGFGAAGAAAAQSPDIRGTALGALLHSLPPLLYCLATANLYLKAQMAHGVLLHWATSAGFTLGLQTALRNPTLRTWLKLNPGQQGGAAAPAPAAGPATATAATGATAATAAGRSYADLPTELVARVAETSDPNVLVIMGAQLSARQHYPGALHCFRKAVLLAPGHVRAHYSMGQVHSLTGGWGVGAWPEAEAAYRAAAQLSPEGPERGQALYCVASALHSQGKFSEAAEAYAAADALWRGQAVVAFGRANALAASGRRQEALEAVAEAEARDAATPGRPFGAVLARLRAQLVMAGSGSDSGGGGGGSGGGGGDGTGTRRAAVRGVRGAASSETALALALALALALVLVLVLALALVLALALVLALALALALALVLVLALALALALALALARCCPAAGGATAAPVPAWATNGRVDVPGTLGIAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SEQ6</accession>
    <name>A0A835SEQ6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Pherophorin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_014892</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000111">
        <property type="protein sequence ID" value="KAG2425888.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SEQ6"/>
    <dbReference type="OrthoDB" id="550638at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032634079" description="Pherophorin domain-containing protein" evidence="3">
        <location>
            <begin position="23"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="843"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="409"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="447"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="521"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="536"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="558"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="585"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="600"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="628"/>
            <end position="657"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="674"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="702"/>
            <end position="712"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="713"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="757"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="767"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="807"/>
            <end position="820"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2425888.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="874" mass="81480" checksum="6A34B3F2B359C295" modified="2021-09-29" version="1">MRSFSLLAGLALAVASVASVSGQADCSASYLVPHLFAAADGSAPPLVVCSPKPNFISNASLVDWSIGWDTAQLPPALTAPGFTVSLPLYGPLLNSSGGSGGGSSSGGGSGDGGAAAPQVAVRPGWYRLVFLPSDASVGVTVDAAILEGGPATDGGSSSSPAGSSYYTSGYGRLHGSLAPTPAYAPLLYLPGGVAGLRLTVAVPPNAPPALSVAFRVEAAAAVVPQCAAPATPLVVAGGAASFGSCLSISGGGGGGGGGGGGGGGLGPTSFSFSFQVFLAGLSPGFKSRAVTAALPPIPLPGGVAMPPGAYTVRLLISTKPGAAAAAAAVTATLCDAGAGGAAAACGGGGGYRGWQLVYSGGSNTGGGSVGSWVAAAEGIGGIGLAVVAAPGAPDQINVGIQIDAVTVGGGGISWPDPPPPPPPAASPPPPPSPPPPQLPTTSSPTPALTPTPTPTPAPTTSPAPTPSPTSSPADPPPPSPQPPAAAAPAPVPTPTPAPAANSSAPTPAPAPSPSPTPTTAPEPSSGSDTSTSSPPASSPPATTPPRSPTSQPPATATPSPPEPSPPAADPLPAPPPSPSASAAPSPSPSLAPAPAPAPGPQVSSPYPASSSSPSTSTSVQPPPPSPPGGDAAASPAPQPPNAAEVVSPPPSGAAAGPAPQPQPQLNNSTGGVTAGASPPSFPGAAAVPPSPASFPSPASGTAPPPSTSPSPSPTSSGAAPGASPQQLASPPPPPPPPLPRPLLLLPPAPPAPQRGAAAGGGGGGGQLQPPGQSAGTTLSPPALAPEPPLATQTDGGGSSLVTDGASVAGGGGGSGSGGRGSSSSSSSGGGGGGGSSSAALVPALATVLPISAVVIAGVALHWWRRSRVKWTLLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SER1</accession>
    <name>A0A835SER1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014902</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000111">
        <property type="protein sequence ID" value="KAG2425902.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="551734at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="204"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="345"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="626"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="717"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="894"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1177"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="204"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="352"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="368"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="601"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="726"/>
            <end position="736"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="765"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="928"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1049"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1117"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1184"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1196"/>
            <end position="1211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1244"/>
            <end position="1258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1259"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1294"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1327"/>
            <end position="1343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2425902.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1374" mass="133751" checksum="0EF272943D4D8DC4" modified="2021-09-29" version="1">MRALVAQRHRRAAAASAAACAHGGSGSGPGAADDAPGEEQQLLLDLADRGTWPQHMCDTALLPPPPRATADDCRGLTAAAAAAALRAAARCPPSALQGLQHPRRQGGAGLTAAGCLAASRAAHLGRQVLHRHGCTPEDLAGTSAAALAALAAATPGGDAAAAAAAAAAAATAANGATAAGSSKAGGKKKPAGVADGAVAVADAVDRNSDGEKAEKSEEKKISKKRKTSDVKKEQQQQGEEGGQEQERGDGEEPPKKKKKKKKKATAEAGGEADGMEVDAAAPEVTAEPKASAMAEPGEGSVRTANGGAGGAGRDAAGGLEAASSQRPAVAAAAALPASPLRGLKGQKLAAPKAPPALAAPPPAPGGEPLPAASGAAAAPPTTPAPAPARASTPSLLAAARSGSVADDGADLRGVPAEQLLHWRTAPALVGRQLGICSGAVGASAVDTPAADAAAAEAAAAAAAAAAAADGVPYLGGSLPAPALGGAVRMLRRLARDSRRTVLQPTTTRLAVSQRAALLRGRELCYRDTSLARHGVLGARARTALILARAWEPPPGALTGAPLSGELTEALAATPSGTLRQRSAEPGAVAPLSVNKPSGRKAAGGGGAGSGSGAAAEASARKAVAEGKAAAGGKGGDKGGDKGGGGGGKKHKQSSGPPPGQGGEDRGRGAAGRAVVSTLSDGDLDEEFSALEYPVTLTRIIEAPSVAAAAAAAARSAGGASSKGAAGAAGGKGGGGGGGGGLQLTKLVDLKSATGSVKRPATAAAAGGGSGAGDGGGGGGGGGGGSLGSRIVRPPGAVPQIMRPRPSGPRNCLHIWFQGKAMPTESTIRDLAQHLPALRKDQWPSVKMDTTPGRARASLTFPADAAEAAARMEALLRASGARLLKLPQQCIQFSTTAAGEEPQPPKWVTAAPPRRPEHGAGAGAGGVQPPGARPGAPGAGAPVTARLPPKPSATLPPAAHRPPPDGAGGYSSVGGRPHAGAGIDRRRGPPPPHHHGTATGLPPQQQQQQQQQQQQHPLGAGGPPGGEFPLDPRGSGGSGVWSRGGGGGDPGFAPPPHHHQHQHMMGGGGGYGGYPPPPPLAAAAEPAPWQNYSPTHPSLDGGGDRRQNDLSTMQAMLLPPPAAPPPQPAHYPPQPAFAGGGGGGGSAVAPMGPPMPMPMPMPFPLGQPQPVAVTQVPVDPRRRAQQQQAAAATAPGGVNGAGAAGGGGGGGEDLYEPEAYDPQPFATAGAGAGAAQQGRQWPGGDAHRDGRRQGEREGSADVGAAGAAAGGSAAVHDGDRDGSSGLGRNGQEGSEAAKPERAERGEGAAGRGRVDELTTPGRLAAAAGDGGAGADGAAGNGGAGPDTEERYKNLFQGLDPDALAALASVVLQPNQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SF34</accession>
    <name>A0A835SF34_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_015302</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000140">
        <property type="protein sequence ID" value="KAG2423602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SF34"/>
    <dbReference type="OrthoDB" id="535245at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAS1" evidence="2">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="66"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="156"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="328"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="66"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="156"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="335"/>
            <end position="346"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2423602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="404" mass="41431" checksum="D5F11962DE9B0460" modified="2021-09-29" version="1">MLDCGKRCGTLQKLPRTVFLPVNVAWNKYFSATGTTLADLTSKKSRKALTALMRYHVLPQVVPSSRVPLSSDVPSSSTGGGSSSSGSGSSSSSVAGEEVETLQGGSITLARRPDTSTIRVAGSRNQAVVLHADISLGTPLVHLVSDVLLLEVTEPPPAELPAPMPSPSPPPPSPSRSPTPSPSPGSGAGSSPKPLSRPGTPATGSTIFNLTWDRNVDMDLIVVASWPETDSGDTMTMFYGYTGPEALIGGGAMSASMAPGGGALTGFYSRTAGSWEALSWPNPLKPAPAVYTICSFFYNLEWAPGTAVSADAPVNPAFTVITGADQNAGAGRGTAGSSSTTTTTTAAGGGEVLVGTLGKPLWKPGEFSFTLLPRNCTPDCPWYLGQVCVDGAGKVRVVSGAERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SHR8</accession>
    <name>A0A835SHR8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_014629</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000102">
        <property type="protein sequence ID" value="KAG2427224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="546633at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000976">
        <property type="term" value="F:transcription cis-regulatory region binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050663">
        <property type="entry name" value="Ankyrin-SOCS_Box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24193:SF121">
        <property type="entry name" value="ADA2A-CONTAINING COMPLEX COMPONENT 3, ISOFORM D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24193">
        <property type="entry name" value="ANKYRIN REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="158"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="281"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="314"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="359"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="404"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="1288"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="12"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
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            <begin position="62"/>
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        </location>
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        <location>
            <begin position="98"/>
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        </location>
    </feature>
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        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="139"/>
            <end position="156"/>
        </location>
    </feature>
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        <location>
            <begin position="540"/>
            <end position="549"/>
        </location>
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    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="656"/>
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        <location>
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        </location>
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        <location>
            <begin position="792"/>
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        <location>
            <begin position="1219"/>
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            <dbReference type="ARBA" id="ARBA00022723"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
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        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
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    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2427224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1354" mass="127501" checksum="F3165D0BB5DE7168" modified="2021-09-29" version="1">MLLCGLLGGCLGGGGGPKRSPSTASSVDGRHVSGPGDSADDVASALTAGGGRHGRLSGNGHVGHHHEHRNVHGGGGGGGHNRHSGHSGAGEGRHGRGRGVSGNGGAPGQNGPLDPSDPAAAAAAVAAATQPVSLVKLDGPGGGGGGANGRGGGGGPPARRTPLHVAAERGQLQVLSALIEGLCCAATASLLQPEDADAAAAAAAAAAGGAATAAGEGGDAADAAVAAAAEAAAAVMAAAEGEGPAAAGVSGSFPVGAPGRSGTPAAPDQYIQYHLNLQDGEGSTALCLACRAGHVDCCRLLLANGADRRLADARGNGPLHYAALRGHLGVLFMLLDEFLSEEPAAREAMAGYVDVRNASGCTPLHYAVWGRQSGSVQVLLQHGADVLPRNSRPAQELSPAVTAAGSTPLHLAAARGHVEICRILLKTFAERVLEPLQLSGGSLQDEVAAAQQPLLAALDPRVQANAQGHMPYQVAQRLGFYPLAMLLRPSIPILRLFSDEERAVRFYGPPPLKALAAEALNKKLMAELDALAEAAEGLAAPPSAPAAAPGAGGGGGGLRPVSAPPSSAQLQQLMAADANAAEGLAAEEAEDAAAAAGASGAGRHSGGSVAASAAGSRRGAAAAAPRMTDNGAVTSSIAMAAMETERPGLMLRGSASGSGSGSGGGSGSGAAGGPATRRGVAPPPRLEVGGPSPSASSSSANVAATAAALAAAAAAACSSGSSPASSLGLVAPATPESGSGSGSGSGTGAAPPPASSPSRMTPLSPGLMSPLGFLPTPSGLAAAIGASPSALSAAAGASPGRSPPSARRALVPALSRERSRNSMLPPPTASSSPGGGGGGGASVAAAAAAGGGGGGGGGGSRPVSSRPGVASPSGGATAAAAAAAATAATSSRAAAAAAGEGDLVLSLLPGQPDLPELQPTSIRLVPSPSGGAAAAAATAAGHGGRRSARPSASGAAGDLLPPQLSPRGAGGGGAAVATGAAGAGAEGVVAAGEMLVDGSVDVSGSLGDAAAAAAAAAAGALLGPRTPARQPSAGALHARRPAGSPSGGGAAAGPGLQQQQQQQQQQEAGAAGAASPSAGARPPGLARLRSNPLFGPASSAAEGGVAAAAAARPSAAATAGEAAAEPLQTAAAAVAAEDSVTTTPVGAMTPVAEEPGEGGEGEGGEGETADGAASEAAATVASSCAAAAVTPFRRRGSGGAAAATSSNSSDDGDGEGEGASKPQQAQQAQQAQQAQSQSQKKDAAAAASAKGAAAAAAAGGGGALAAVLAIQTGGGGGGNDDEEEEVECGVCMEPLPLVAVSPCRHSLCGPCARRIVCLNITKPSHCPFCRTTITAFVPVAAAAAGALPGQPLAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SI90</accession>
    <name>A0A835SI90_9CHLO</name>
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        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
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        <name evidence="3" type="ORF">HYH02_015012</name>
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    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
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            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000116">
        <property type="protein sequence ID" value="KAG2425402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
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            <end position="110"/>
        </location>
    </feature>
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        </location>
    </feature>
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        </location>
    </feature>
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    </feature>
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        </location>
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    </feature>
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            <begin position="1069"/>
            <end position="1110"/>
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            <begin position="72"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="EMBL" id="KAG2425402.1"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1178" mass="117451" checksum="82143EFEB35AA576" modified="2021-09-29" version="1">MPPHAPYVCRTCVSTAAPATQEQREPAGEAATAAAFKPGAAGASCSSAATGVKPPQGSGGQLLLGPASSQQKATLGWQQQQQLHSFAPADRGQVRGLQAASAAGERDSCTAAETQELWDADGGSAPTAPEHAAAAVQQAAAAELDAAADLEPAHEEPPAPRPRRQVRVVQGWTNLRLLATTSAAAVAVAVVPPVADGGDEQPTAAGVEPSASPPAAGGPSDTWTLGQPACAALMAALVAAAAASKTPARGGRRGGVGSLVPRWRCTCQLIMQHFGLVGRAECIYNKHMGRCKGPIYEVTSAGVQAEFRRPPLAGRAPPPTFLVHGPCLEDIRVSNGLEAKWGPGAKGKQRAVGPVLPRPAEAVIPSVQQLAVALTATLLSGSAAPAAPAEEAAEEQEQTQPLPLISLSKLGGAGSTATSAAQPPAGGVPDAGGGGVFAGGSNTGGGRRGALATTVMPSHILCQRLRALHPRAAAVADGLAGTAAVASLAGEGSGEDGGSSSSSHVSAPRSSRVLPAAAGAPHRQGLLGGAGSAAMAVATAKHQQRPTLRSLTGGAQAGAAAAGLVGSQHTSMAPPPALPLQRLLPPAPTMAAAMPRSGSLGAPGSGTMASVPAATSGGGLLESAWVELQVTAYTELEVPPEKRLSGGGGSGGGGRSSSSSFSQGGCASNLQAPAVAVCDVDQRADLYALSPGSWVLLTASVSDAAFILHVRPHMPRGARLSPCTGIQPFAIARVLRARPLSPDAAGATAAGGGGGGGGMTIVELEPSSWHWVVDRGAVEPSKQLPGIDLLREPDISPRQRAQMPLAAARVALTATLLSGSAAPAAPAEEAAEEQEQTQPLPLISLSKLGGAGSTATSAAQPPAGGVPDAGGGGVFAGGSNTGGGGRGALATTVMPSHILYQRLRALHPRAAAVADGLAGTAAVASLAGEGSGEDGGSSSSHVSAPRSSRVLPAAAGAPHRQGLLGGAGSAAMAVATAEHQQRPTLRSLTGGAQAGAAAAGLVGSQHTSMAPPPALPLLPLLQLPAPHLRLAGGAAAASEADPGLRLSADTDQPALLPEGVAHLLRAEQRDALRAALQAAEQRNGQLQSQRDALRAALQAAERRNGQLQSQRDAAWAAALQAAEQRSRQVQQQRDLAWAASVLELQQRNQQLQEERDAAVAEADSVWADLRQALIDRLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SIY0</accession>
    <name>A0A835SIY0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_014833</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000107">
        <property type="protein sequence ID" value="KAG2426406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SIY0"/>
    <dbReference type="OrthoDB" id="5204190at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00105">
        <property type="entry name" value="KH-I"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.10">
        <property type="entry name" value="K Homology domain, type 1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004087">
        <property type="entry name" value="KH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004088">
        <property type="entry name" value="KH_dom_type_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036612">
        <property type="entry name" value="KH_dom_type_1_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10288">
        <property type="entry name" value="KH DOMAIN CONTAINING RNA BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00013">
        <property type="entry name" value="KH_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00322">
        <property type="entry name" value="KH"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54791">
        <property type="entry name" value="Eukaryotic type KH-domain (KH-domain type I)"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50084">
        <property type="entry name" value="KH_TYPE_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01159">
        <property type="entry name" value="WW_DOMAIN_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="WW" evidence="4">
        <location>
            <begin position="497"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="67"/>
            <end position="112"/>
        </location>
    </feature>
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        <location>
            <begin position="186"/>
            <end position="214"/>
        </location>
    </feature>
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            <begin position="361"/>
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        </location>
    </feature>
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        <location>
            <begin position="470"/>
            <end position="512"/>
        </location>
    </feature>
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        <location>
            <begin position="36"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="80"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="189"/>
            <end position="201"/>
        </location>
    </feature>
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        <location>
            <begin position="365"/>
            <end position="376"/>
        </location>
    </feature>
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        <location>
            <begin position="377"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="470"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="491"/>
            <end position="500"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00117"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2426406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="532" mass="52774" checksum="A9E1811EA51B7CC9" modified="2021-09-29" version="1">MADHEEPPPGTYEGEERAPGVDTGSSHLPPPPEPHAAPQEPAADQDALLAGRSRAEMLAAMFAAQGANVGTSDPSGHKRKLDDDANHDAPDSKRPASMAFGDSGPLPPPPPLGALGADVAVAMETVMCPPDKVGRVIGRAGATIRDLEASTGTRIQVDHKAPGDKPVTISGRADEVERAKRQVLDLISGHGGGGGGGGGGPDSAPAPGEAQKSLECPQGIVGRVIGRGGETIRTLQQASGAHILVNQDFPDGVPRQITITGSQDAVDRAASMVQELIGGEHSNTQQVIQRFGVGSTEVLECPKTMVGRIIGKGGETIKDLQKRYNASIQIDQSSMPCKVTITGPSHTISAARHAIEDLIRSTGPPGMGSGGGGGGSRPPYGAPYGQQYPGSGGGGGGGYGGYGGYGAPGGYGAPGGYPGGYPSGYPAAGGYGGYGGYGAGAYGAPGAQSSDPYGAGAGSNYYGAGAAGGAGSGAPGTSGAGAGAAAPPGTNGSGGSGGSGSPWQALQDDQGRTYYYNSTTGVSQWERPVDMP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SMB9</accession>
    <name>A0A835SMB9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_014863</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000109">
        <property type="protein sequence ID" value="KAG2426108.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048306">
        <property type="term" value="F:calcium-dependent protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051426">
        <property type="entry name" value="Peflin/Sorcin_CaBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212:SF3">
        <property type="entry name" value="GH27120P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46212">
        <property type="entry name" value="PEFLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0106">Calcium</keyword>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="402"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="7">
        <location>
            <begin position="438"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="39"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="280"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="631"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="789"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="921"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1151"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1283"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="39"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="93"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="123"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="292"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="634"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="841"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="856"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="936"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1294"/>
            <end position="1307"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2426108.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1307" mass="134534" checksum="2A7330E33482BE3F" modified="2021-09-29" version="1">MAAVDRLRSFYGDQLMCRTGTLASIKSFGSAASGVASAVSGADASTVAHAKQRRAGDEDVVIDPYQLDPDGSSSDSSDEDKDGLSRTDSGSGIDDDDEDGDLDEAEWTSASGDELGPGPGPDSVRSAAATATSLRGAGGGGRSVAAVSTRTARSAKSHKAGGGELSGANAGGALRSGKGVSIADVPLFQGPKGPRSVAASNWGARSRRSVATTARSVATSAVSSAALSAMPSGAPGGVVSVQKLDARLAGRAVRRRLLRRRGWEFDLVPDEVDYTLGRELAHELTRPQPTADSDEEPEEDEAGGDDGDAELVDARAGGCPPSGPVLEAIKSYAHERAPEVVWSERVKHAKRVARQTGQTVTVRGRLEPKKRRELARKIQKWDNREWFNSRKRAPPAPPLHPAVERVIEQWFQLVDDDGGGTLDREELLTALQASDVPVKPENIDEMVALMDLDRDGVISWKEFVTFFMYEFAAGKNLLSGEYVLPSGVALPFGAMIAKLKRDRLVADLMQGGHARAKWQNIADSPIALEDELGMMAAVELAMEEMKNPALGRARARAAKALNKLPPHLRTPSIARHLQRHPEVADKLLRAPSMAALMAATSLKRAPSATNIVARLASTNSNGSIASRTSSMAGVGAGSTGGGSTSGGGGGGAPAARVGNVDLNVAVAMAAGLEWPVEGASFYNKRAKTVLRAACQKPPEAILRANQAAGPSAGAVQSTTSRGVAARAGASGAVAGGVAGGGMLTAGKGPSLRKQVSGRKGLSVEAVAAASATAAAMEVDTSQARAHFLRGGARGEGCSRRGSRRRGGSESSGDEGGSGGRRRNRRGSGSSEEVLPWLVNAKRREEEERQELRERLMGGASSMSAAATVLAAGPSSRAKADAPQPRSEASDAGGDEEEEGLWVSPLLKRWLTVERDRLLQPSGELAAARETAEQHNTDAATTSEKAGTEATSAPQPSQTGSAGPSRAASASAPLEVVVSEVSVSSPAAGTPPVRAVSSTLDGELEGPATLGGAISTAARKPRRRMRFVDEAEDAALAEEEASTAIDGAASAGAEEEAVAAMTDRAQATVFANSSAPPVFLGSLGPHTCAVGPLQAQGATTLATAKAFVELPDDPSASSLRAIRRSVLLGVATDGDAGPAAALQSTLGLLPGQSPRASGGVLRTSRVETASPLPGGGAPPSGEVGAAPPGASPLRSSYGPALQQWALGSAATSATGDAISLEPLDSEEARELMAGITLQLSKEEVLYHIHTGYEADRPTTSDFRAALTRMRLAAAALVHSYALPPHPEASAEPVPRLRALAAGAGPRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SQI4</accession>
    <name>A0A835SQI4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">AP2/ERF domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_014496</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000098">
        <property type="protein sequence ID" value="KAG2427893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SQI4"/>
    <dbReference type="OrthoDB" id="610645at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009873">
        <property type="term" value="P:ethylene-activated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00018">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.730.10:FF:000001">
        <property type="entry name" value="Ethylene-responsive transcription factor 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.730.10">
        <property type="entry name" value="AP2/ERF domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001471">
        <property type="entry name" value="AP2/ERF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036955">
        <property type="entry name" value="AP2/ERF_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016177">
        <property type="entry name" value="DNA-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044808">
        <property type="entry name" value="ERF_plant"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31190:SF374">
        <property type="entry name" value="AP2_ERF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31190">
        <property type="entry name" value="DNA-BINDING DOMAIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00847">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00367">
        <property type="entry name" value="ETHRSPELEMNT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00380">
        <property type="entry name" value="AP2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54171">
        <property type="entry name" value="DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51032">
        <property type="entry name" value="AP2_ERF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="2" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="AP2/ERF" evidence="7">
        <location>
            <begin position="573"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="190"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="290"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="509"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="632"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1016"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="190"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="311"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="329"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="407"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="522"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="540"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="551"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="569"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="645"/>
            <end position="665"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="666"/>
            <end position="675"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2427893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1203" mass="116737" checksum="C1F9BD1AE536BD7A" modified="2021-09-29" version="1">MQGLQAAQAQLQATAQANAAAQAAHAQAQAQLQAAEAAKAAQQGTSTSRAASPDGNPTQPAAQVPAPGAPVAPGAMPALPRPPMPAAVPPAAPAPPSAVPPSPAAAMQALVSAQAALQAAQAQMAAAAAAAAAVTAAGQAQASAAAPGAAPPGTVPTPAQLQAQAQANFQAQLAAAQQLRNAAAAAAARPPFPGAPVPGQPAPGAPATALPPAPVPTAPPPLGTPPAPGSVPATAPPQPAGTLPAPGQPGAVRPPAVSPAIASQAVAAAAAAAAAAAAAVAGVRPPAPGAPLMPPPASAPAPMHTPPPLQQQPASTQPPAAPGAGNQPPSSPPAPAPTIPNPSTSPPAPPAPSSMPPPPAGLPRPTEQSPPPGAIPPGGGLVSSLPPPPPAAAPTGSGGAPLPPPDLSGLPPGLPPGMTLPLLGPDGQPLDPDAPLTEAQQLQLSEAMQAQMEQQMQMMAAQQQMMEQAGMQLPPGMQFPFPPGMPFPPFPPGMPLPPGMQLPPGMQMGMPPLPMPPMQMMQEEELEPESSDSDNELASPRKRREKKKAPRGGGGGGGGGGGEDVVSKGKNKTYRGVRQRPWGKWAAEIRDPTVGARRWLGTFDTAEEAARAYDAAARAIRGPAARCNFPLSASHDDHYHHHHAQQQAAAQQQQQQQMEAAAMAAAGGGMGGPNGMGPPMGLMHGGPMGSVPEDEPLPGGPPPLMEQPKVKLPAAAGLKLRGLKQKAGMRKSGMDEPLIQSAMHGGLGAADIHGAMSVNDAMAAAGGSGGGAMPGMNGSPGNPFQMRIKTGLTPNFSGWHGPLPPGVAGSLGASAMATSIGNSSGGLLAHFPPLPEWPPAGSMGSAASMMMLGMSPGAGEAYGTSYGNQYGKSVDMMDMCAQLLEAGVMDPLATIGSLRNELVVPPDFKSEGPNAGGDGDLDGVHEMDEMMILGTTPDFGRPSNDFFKQLPGSYGAGGKLVAGKAAAAAAAAAAAAAAAAGGGAAVGPGAPSGTLTLAPPGSVAAAAGAGAGALPFGSRGNSPPSDVPDLGAAAAGGGGGGAVVGSPLTNMLLHGRHHGGGGGLVGDPALLGMGQLSTDGAALGVGGNDEDDYLMGMSPDLPTSGGKGKPPAPGIREPGFESFMKAHAAQAAAAAAQAAGTPKGAVAAAAGGSSGAPSIELPVSAVGGGSPNRDTAGTSELLSPTISLAAGVAGHELPPPDKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SVQ0</accession>
    <name>A0A835SVQ0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_013568</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000077">
        <property type="protein sequence ID" value="KAG2430728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SVQ0"/>
    <dbReference type="OrthoDB" id="545402at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="978"/>
            <end position="1091"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="465"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="722"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="796"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="102"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="982"/>
            <end position="991"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1035"/>
            <end position="1046"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1072"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2430728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1091" mass="117572" checksum="59B5DED750923363" modified="2021-09-29" version="1">MEGGEDAKAALFSAVSRALESYERGAVNPQHFSALLEQLQLVLEQALTDVPGAKEHDQDGKEHGHMETLYRAGGAFGKSTAGSPGGLSTEGTSSSWTSPLRAAAGAALHGGQPSGKQPSASPAGRWLARQTHHKEAQELRRENAALKQRVSELGDAEARMEAQARELEFARERAGPDAPRSVQEQQLLTRLGQIQAANDSLKQQLADSRAEAAAAGRAHAAGASRAEVVLMGELEQHRQAAAAARRDLARQAAAAAREKEAMEHEARRWQLAASQAAAVAEKTQQKVASVEQKLEAQVAQVRSMATDLAARGRELGALQQQLTASRAALAARNRYLERLDAAVLQPLLSWHAEADPAVAAALLIAGGSVGSGPAPGRGLPRSRDFVQLKFRAEAILGAAAADVDSAAKRHAAAAAAAFEALAARITSLKQEVESCSAAARSQIAEAEARMGRSLEEVRASAAQQVRTVQDQLQSTLEAKAQLREALAAEQATAAVRTSELARLSEREVRLALQVEALGAELAKLKAETSRALKDQEAEAEATQKQRAEAAFERGRQLGDRQAAATVTALKGELQDAAMQLQASRKEVAMLTSQLEEARSAAESFEARLSDARQEAHKARVESEERLRRDADCRLAEAKASAERRAQLELQDHALALQRERERGERALADAKRAGELAVEAARREGELLLQRAAGEAEMQLRAAMSQAASQLKLTEERHLLATQDAERRISALSEELRLANDKAAATQEKCEQLIAQVYNVTQELQKVRQALSDQEAAATAAAQDQASTIAELQFKLLECRQRLAAQAEQLEQITQRQEDAQVHELEAARLAMEHMAAERDDLQAECVALTQQLSSAQAAAAGVEVEMDTLTRALEAHKAARAAAEAAAEEARRSAAAAAEAAEEGAARVTALQQQLGEQQRLHEREIGLLDARCQAELESAKARYRAELEGLQSGLKLLRLKQSRVMAYVEDVFQEEQEQLEQQHHNHNQQDRGGGTWAAGLKGGEEGQLQEQQQRSRPGRTLGPASRQPGGPRRGADEGPDEGKVGHAGALGVGWRDAGAERPPRHTLWQGDRRSVVRNDEQSTDGEDEW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SVQ2</accession>
    <name>A0A835SVQ2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_012964</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="2">In the C-terminal section; belongs to the trehalose phosphatase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">In the N-terminal section; belongs to the glycosyltransferase 20 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000067">
        <property type="protein sequence ID" value="KAG2432392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SVQ2"/>
    <dbReference type="OrthoDB" id="755951at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004805">
        <property type="term" value="F:trehalose-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005992">
        <property type="term" value="P:trehalose biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03788">
        <property type="entry name" value="GT20_TPS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01627">
        <property type="entry name" value="HAD_TPP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000010">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000052">
        <property type="entry name" value="Alpha,alpha-trehalose-phosphate synthase [UDP-forming] 6"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000079">
        <property type="entry name" value="Trehalose-6-phosphate synthase 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001830">
        <property type="entry name" value="Glyco_trans_20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003337">
        <property type="entry name" value="Trehalose_PPase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00685">
        <property type="entry name" value="T6PP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788:SF94">
        <property type="entry name" value="ALPHA,ALPHA-TREHALOSE-PHOSPHATE SYNTHASE [UDP-FORMING] 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10788">
        <property type="entry name" value="TREHALOSE-6-PHOSPHATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00982">
        <property type="entry name" value="Glyco_transf_20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02358">
        <property type="entry name" value="Trehalose_PPase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="703"/>
            <end position="743"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="703"/>
            <end position="714"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="723"/>
            <end position="742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006330"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2432392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="823" mass="89976" checksum="A00FF95F659CDFD3" modified="2021-09-29" version="1">MYVGSLPVDVALEEQDAVAAQLKRLYNCCPVFMEKELKEKFYKGCCKQQMWPLFHYVLPMSPESSGRFDQEMWQAYVKANKVFCEKVVEESATDTDYVWIHDYHLLVLPSLLRKRFNRIRCGLFLHSPFPSSEIFRTFPKREELLRSLLNADLIGFHTFDYARHFLSCCSRMLGLEHETSRGSITIDYYGRTVGIKIMPTGVNPKRYLDGFSWDEFKWRRGELVAQYAGLTVLVGCDDLDVFKGVELKLLALERLLDTHPEWRGQLVMVQITNPPRSTGRDIAELHRCVLGLVDSINRKYGKGSYQPVQYLERHVPLHERMAFYSIADCAVVTATRDGMNLVPYEYVVCRQGPDGWDGGGGAGGAPGGGGGPGKRESMLVVSEFVGCSPSLSGAIRVNPWSVESTADGIYAAIKLPREHRALRHDKHWRYVSQHTVAYWATSFVADLQRVTKNHVAMKCYGLGLGLDTFRMVALDANFRRLEERAVAASYASSHFRAFFLDYDGTLTGASPLGPTSASASAASSSSGLTAGGLHGPGGLAPSEPLLAVLRALVADPRNRVFLFSSSPKADLTQWFASIPSLGLVAENGFFLRAIGSATWETAVPHADFSWKRMAAPILQQYVESTDGSSVETKESALVWHYRDADPDFGAWQAKELLDHLEGVLSNKPVEIVGGQGYVEIKPQGVSKGRALERLLAAASAPAASSSSTAASGAPPQAPPAAAPSPSSSPAHGGLVGPRPAAAGPGGLLGGPDFMLCVGDDRSDEDMYTSIENMKSLPTMTAEVFACTVGQKPSRAPFYLNDPAEVLQLLARLVNVPLPHQAIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SVQ3</accession>
    <name>A0A835SVQ3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="12">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_012503</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RecA family. DMC1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000060">
        <property type="protein sequence ID" value="KAG2433958.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SVQ3"/>
    <dbReference type="OrthoDB" id="10251254at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000794">
        <property type="term" value="C:condensed nuclear chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140664">
        <property type="term" value="F:ATP-dependent DNA damage sensor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000150">
        <property type="term" value="F:DNA strand exchange activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003697">
        <property type="term" value="F:single-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070192">
        <property type="term" value="P:chromosome organization involved in meiotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000730">
        <property type="term" value="P:DNA recombinase assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042148">
        <property type="term" value="P:DNA strand invasion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006312">
        <property type="term" value="P:mitotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007131">
        <property type="term" value="P:reciprocal meiotic recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000239">
        <property type="entry name" value="Meiotic recombination protein DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.20">
        <property type="entry name" value="5' to 3' exonuclease, C-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011940">
        <property type="entry name" value="Dmc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016467">
        <property type="entry name" value="DNA_recomb/repair_RecA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010995">
        <property type="entry name" value="DNA_repair_Rad51/TF_NusA_a-hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013632">
        <property type="entry name" value="Rad51_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020588">
        <property type="entry name" value="RecA_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020587">
        <property type="entry name" value="RecA_monomer-monomer_interface"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF003301">
        <property type="entry name" value="PRK04301.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02238">
        <property type="entry name" value="recomb_DMC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942:SF30">
        <property type="entry name" value="MEIOTIC RECOMBINATION PROTEIN DMC1_LIM15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22942">
        <property type="entry name" value="RECA/RAD51/RADA DNA STRAND-PAIRING FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08423">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005856">
        <property type="entry name" value="Rad51"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47794">
        <property type="entry name" value="Rad51 N-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50162">
        <property type="entry name" value="RECA_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50163">
        <property type="entry name" value="RECA_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="5" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="7" id="KW-0469">Meiosis</keyword>
    <keyword evidence="3 9" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-0539">Nucleus</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RecA family profile 1" evidence="10">
        <location>
            <begin position="75"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="domain" description="RecA family profile 2" evidence="11">
        <location>
            <begin position="254"/>
            <end position="317"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008897"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023254"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU003422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50162"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2433958.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="317" mass="34030" checksum="F4549F676BF7789B" modified="2021-09-29" version="1">MRAVQVAHPSADIKKAKEGGVHTAQALLMIPKRHLAEIKGLSEAKIEKMVEVARKLVPGAGWRTATEAAQAREREIIKIKTGSSAVDELLGGGFETKSLTEMFGEWRCGKTMLAHTLCVTTQLPQEEGGGSGKAAFIDTEGTFRPELVKQIAERFGLDPDAVLGNIVVARAHTSEHQADLLISLTALMAEEACFRLLVVDSLTAPFRTDYTGRGELAERQQKLNNVLAKLKKISEEFNVAVVVTNQVVSDPGGGAMFVSDPKKPVGGHVMAHASTTRLSLRKGKGEQRLIKVVASPCLAEAEASFCCSATGVNDFKD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SVS5</accession>
    <name>A0A835SVS5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cyclic phosphodiesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_014175</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000088">
        <property type="protein sequence ID" value="KAG2429139.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SVS5"/>
    <dbReference type="OrthoDB" id="514292at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004113">
        <property type="term" value="F:2',3'-cyclic-nucleotide 3'-phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009187">
        <property type="term" value="P:cyclic nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1140.10:FF:000007">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1140.10">
        <property type="entry name" value="Cyclic phosphodiesterase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012386">
        <property type="entry name" value="Cyclic-nucl_3Pdiesterase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009097">
        <property type="entry name" value="Cyclic_Pdiesterase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28141">
        <property type="entry name" value="2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28141:SF1">
        <property type="entry name" value="2',3'-CYCLIC-NUCLEOTIDE 3'-PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07823">
        <property type="entry name" value="CPDase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55144">
        <property type="entry name" value="LigT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2429139.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="192" mass="21207" checksum="0584EA91A36E2F10" modified="2021-09-29" version="1">MSAPEALRDQYSLWAQPKGRLGEQLKAEIAHLAARHGAPAFPPHTTVLGDIERPGGRQEVLAVAAELAKKVKKYRINFTDVTRGPIYYQCVYLRVAKDDGAMAAAATAREVFGTTTGPYMPHLSLLYSDIPEEERAKAVEYETARLYGESSGYDTLLVENGYEVDSFAVWYTPVADKSLKSWCLVGEFELTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SW04</accession>
    <name>A0A835SW04_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012363</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000058">
        <property type="protein sequence ID" value="KAG2434347.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SW04"/>
    <dbReference type="OrthoDB" id="548633at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00302">
        <property type="entry name" value="cytochrome_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002401">
        <property type="entry name" value="Cyt_P450_E_grp-I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00463">
        <property type="entry name" value="EP450I"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="12"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2434347.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="329" mass="37512" checksum="D4C4709667CB8BB0" modified="2021-09-29" version="1">MDFLAKLVLSVLITPLLYGLYLASQVLWPYVKSIPLRRRLAHLPGPPVTGWFILGNVPDLVRTPVHQCMAQWTERYGKIFKVELPNTTAVVLTDPEAVAQVLKVERFEKLTTSYQNMEKLTAEQQPNILTEPLSAYYKAVRRAVTPAFSTANLKRFFPRLLDITQRAMAGLEAAGPAAALDMDRLAQRLTIDVIGSFAFDRDFGATTDIAQPNEALQVVGELMTALQRMLNPLNRWFWWRKEARWLWASRRRYDALVRRALEDLRARPPAEHTLLHHLMHLTDPDTGKPLSARRLRCETALFWIAGFETTAHAIGWTLMFIAGSPERRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SW42</accession>
    <name>A0A835SW42_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014493</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000098">
        <property type="protein sequence ID" value="KAG2427890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SW42"/>
    <dbReference type="OrthoDB" id="419711at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242:SF1">
        <property type="entry name" value="MYND-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12242">
        <property type="entry name" value="OS02G0130600 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="22"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="133"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="291"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="330"/>
            <end position="352"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2427890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="385" mass="42355" checksum="A13943B78B2F90C3" modified="2021-09-29" version="1">MSSPPPSSMPPPPPPGDVYHDWAPYVSVFLICLANFLCYFCNDNGLFGRWLWKRHGRSAFFASNTRGGRGWKHSLPNTFWAFDALDPKSVVTSWFLGDWGVLVVHVLTLTWLMVCLIVEATKNGPVNGEWVTYFTHWSLVLLSFAGGVAMLNHIRYMWRRTKAGLSLSRVSPEPSLVNVNVTTAVGAEELGEAGGGVHPKHMADAAAAAAAGKAHNAADDAATWDWLSCFSQLTMQTAVNAAFFLDVYYWVVLIAIQGDPVEGPATQLKHGGNLGIAALEVFLTRMPIVSVHFQATLAYGTAYLVFLWIYGSVSGTWRYSLNWKKTSTVIMHAAVPIALAVFMLIWWGLAMLRDVMGAAFNRWRTRRRHPAPSAMRDPGAAALQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SWQ1</accession>
    <name>A0A835SWQ1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_013989</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000084">
        <property type="protein sequence ID" value="KAG2429649.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SWQ1"/>
    <dbReference type="OrthoDB" id="547225at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="WDR48"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862:SF14">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="347"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="372"/>
            <end position="388"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2429649.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="451" mass="47242" checksum="AED23F79A5FCE2BF" modified="2021-09-29" version="1">MGKATIANLKRNGKRRLHQTARGKRGCRRRPYHATVELYHRPAAEDGTLVGQSPNTTAGGLPEHLRAHCASPALVPWCNGTLYRFDTGNRRSGEAKFRSDGVAEWPSMRVWGWPGAYLMVVWAAGSDADAYKIEPLVLAFTLESCQFGEMLDLEAAAKQFSSAAASSSSTGGVARDRLALISGCQVCPLRQPAPYAPSITRCPNSAACTHEEAVLVFAPPAADGTSGPAAATGGGAPASDGGGGTTYIATEEESTVLGYLGVDDLRSVALYSCLKLNGSALISGVGDGGSGGGGGGLADDVGCYNTTYMTLLCAPEYEGNLCGTCVPGYSLDSNFQCSECPPLGRTIGLGLFSVFIIVTLIVYTAFKNVNEVERPSPKEEQSPTEHADSSSSGGSSAAEEETDTSDIIKVVIVHVQFYIIICRLNIDYPPLVTSLSDAFRIVTGIGSPPPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SWT9</accession>
    <name>A0A835SWT9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SRCR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_013375</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <property type="protein sequence ID" value="KAG2431388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6477838at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="Scavenger receptor cysteine-rich protein type 12"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="SRCR-like domain"/>
        <property type="match status" value="11"/>
    </dbReference>
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        <property type="entry name" value="Vitelline membrane outer layer protein I (VOMI)"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
    <dbReference type="InterPro" id="IPR036772">
        <property type="entry name" value="SRCR-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="VOMI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036706">
        <property type="entry name" value="VOMI_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48071">
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48071:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="11"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="11"/>
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    <dbReference type="SUPFAM" id="SSF51092">
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    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EGF_2"/>
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    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="2328"/>
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        </location>
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            <dbReference type="ARBA" id="ARBA00023180"/>
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        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="PROSITE" id="PS50287"/>
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            <dbReference type="EMBL" id="KAG2431388.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="4739" mass="477873" checksum="332DFAD0F73ADD12" modified="2021-09-29" version="1">[encoded data, 4739 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SY52</accession>
    <name>A0A835SY52_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lysophospholipase NTE1-like P-loop domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011769</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000052">
        <property type="protein sequence ID" value="KAG2435472.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SY52"/>
    <dbReference type="OrthoDB" id="421051at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056556">
        <property type="entry name" value="NTE1_P-loop_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24179">
        <property type="entry name" value="NTE_Ploop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lysophospholipase NTE1-like P-loop" evidence="2">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="208"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2435472.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="276" mass="25722" checksum="567318A88789C139" modified="2021-09-29" version="1" fragment="single">MAAQEEEYRFIVLEADVAASPWSSVCVAQADCILLVAPEGSEPQLSGPESLLVFNAASPAFARPKAARSGLTPGGPTAPLSRGMTPAASAAHLGGVAAAAAGAAGAGSPPPAAAAAAAPGRSPLRFSGVAAEAAAAAEGGRGSGGAGGGGAGGGGGGGGGAVGGVGASMHPFQAKGLAHQQLYGGASNPAMLRRVELVLLHSTAASNSGGGRGGGPGGGGGPGGGSRAGGAAGGGGGGAGAAGANIPHGTAQWLALRPNLSRHHHIRLSRTADIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SZY3</accession>
    <name>A0A835SZY3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013444</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000074">
        <property type="protein sequence ID" value="KAG2431314.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SZY3"/>
    <dbReference type="OrthoDB" id="541563at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="242"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2431314.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="281" mass="30916" checksum="FC769AB8225FFBC6" modified="2021-09-29" version="1">MAYSHRPSILHRPQRAQPSRATEESVESQYEREQALLRAKSARQQEAHSRLLRSLHPQQEDKVAAWEELVAANSMLASRGQRDKELAPQSQVPSPGAQTALPDGARPWHHATATQQYSVEAEEAARRRFAAEVAAENQRLARERELARAMERHANRREPADPSTWYSRGDSHAYAQSVLFTGDGVPAPLRASCTMPVQTQPHTAGISATTSMAGAPPGAQQQQSRPGTAAAPWATWGDAETAAPQKPAPQAYQPAPQQPGLQPWAPKVQERNYPWSWTGPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T0B2</accession>
    <name>A0A835T0B2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014120</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000087">
        <property type="protein sequence ID" value="KAG2429186.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T0B2"/>
    <dbReference type="OrthoDB" id="544020at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="457"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="558"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="748"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="467"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="629"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="667"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="684"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="804"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2429186.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="926" mass="93482" checksum="DA8F22A0FF10FA4B" modified="2021-09-29" version="1">MVEPASSPEQRMQPGASPSGRHHTEQTSSRGPAVTREGLATPPVSKPPVRRGSGAKLRESGDSISGALPPAALGSPAGGRGSALFAGGVTGRVGSTSVRFADPIPASALKRDGNQRDTTVSGGGAEQSDISGLQLPGAAPAPGPRISRVRLADDLGNDNDATSGAASETNVSMAGCQSRASSGTSVVGANKPDAAESRAVTQLASKLIARDINYRQEFEAIMETFGAVFPKSCLETFFETHSISLPNNRQLMILTLYQAGDNGDRIDGVSLLKDLDRAAFKRFAIASGRGPPGAEAGGKRSSITSVQRSDKSRILTLVSTQLNRDKSFSINAGGDELTDAQHIQELIEQIDLNNILIPIGTRAKYVPATDDPESFQVPVWSLRAMHKRKQERERFLIGNDPDFKKLGQTGRDALRKRLARRSMFQQQEIIANAVVAAARAAVEPSVRRVEHSIHSATASRMGSFQHSLSGSLTRGGSLDAHGGPMRPRSAAPPRAPGGASASGAFRPVSALPPRAPAASTLPGNWTLGAGVGVSPRGGLSVKPVTVAPVGPSVPPVMAAKRPSEPDATPLRPAPLLHGADKANTYGGADANNNTLHRNGGGIGVGIGRAPATPPHVAPRSPAHTTPFGHAGGGAAAAGAGAGNGHELDAAEAAIRRLAVKSFGRAPEPVDRSGAGHEGRQPLMGAAGASAAGAGAGAGAAAAAGGPPRNPRRSTDDNGISDFQGACNSTDVSDAGAAAAAAATAAVARTPGAHVPSVTSFSDRDASGLVPAEDGQSGAAHHLPHPDPPSPRLLYNAAVRSASGAARPAAQPTSSRPATSASGGSAAAHGRSPRPSSDAPLAGIAPPRPPSQDAAARSASGINKHLYAASRASGTGSGSGTLRGASADLSDDEGGELPGQMLAILAPAASAAAAATTPLRSQRSNIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T1D8</accession>
    <name>A0A835T1D8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase M41 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011309</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000047">
        <property type="protein sequence ID" value="KAG2437048.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T1D8"/>
    <dbReference type="OrthoDB" id="511013at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045037">
        <property type="term" value="P:protein import into chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.760">
        <property type="entry name" value="Peptidase M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000642">
        <property type="entry name" value="Peptidase_M41"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037219">
        <property type="entry name" value="Peptidase_M41-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF37">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01434">
        <property type="entry name" value="Peptidase_M41"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF140990">
        <property type="entry name" value="FtsH protease domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M41" evidence="2">
        <location>
            <begin position="73"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2437048.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="391" mass="41606" checksum="69FD5BF58E75AFC4" modified="2021-09-29" version="1">MAGFTGADVMGLMARAARMAARQGRHAITEDDIYAAMENKTMEATLEASTAGDGGGLVGGEGVEGSPDPIPPQLRRAVSVYEAGKALLAYITPDYEEIARVSVCPLNVLTGFTLFVEDEDKNVNAILTRSELEGRMVVHLAGRCAEKLVMGEGQMTGMGSPDLFHANLIAREMIMSMGMGRRTGPIDLLRVAATSEAAAGADTLRAGPAAAEGDPFYYHTTDMSTEQARVALAEVVELLDAAEAKAMYGLAINWKALQALTQALLDRGTITGKEVAHILESNGVIHFPDPYTTGFGWDPDGSLRYPFKPDTPPQGGSGGEGAAAVAAEGAAASAAPDLSGARGKTWFAGTPYDAPRNPDGTFKHGWHWNMPFSVQTELPDWYKKEVERYSY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T2J8</accession>
    <name>A0A835T2J8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">phosphatidylinositol N-acetylglucosaminyltransferase</fullName>
            <ecNumber evidence="2">2.4.1.198</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">GlcNAc-PI synthesis protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_013763</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Glycolipid biosynthesis; glycosylphosphatidylinositol-anchor biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.198" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000079">
        <property type="protein sequence ID" value="KAG2430401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T2J8"/>
    <dbReference type="OrthoDB" id="734129at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.2000:FF:000026">
        <property type="entry name" value="Phosphatidylinositol N-acetylglucosaminyltransferase subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013234">
        <property type="entry name" value="PIGA_GPI_anchor_biosynthesis"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08288">
        <property type="entry name" value="PIGA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="3" id="KW-0337">GPI-anchor biosynthesis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="PIGA GPI anchor biosynthesis" evidence="7">
        <location>
            <begin position="48"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004687"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012420"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00032160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08288"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2430401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="272" mass="29722" checksum="E3FF178F676B1FD3" modified="2021-09-29" version="1">MAAAEARQHRVVMVSDFFYPNFGGVENHIYQLSQCLIHQGHKVVVVTHAYGDCLGVRHLTNGLKVYYLPRLPFYQQSSFPSLLGWARLLRAICLRERATMLHGHQAFSTLALEACIHASSLGLKVVFTDHSLFGFADAGSILLNKVLKAVLGADVHGVICVSHTSRENTVLRACLPPAAVAVIPNAVDTSQFTPDMSPGAVAWPRDAEAEEVVLVVLCRLVYRKGIDLLSLVLPAVCERHPNVRVLVGGDGPKRQLLEKVGIKFARLACTAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T3H2</accession>
    <name>A0A835T3H2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_010960</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000044">
        <property type="protein sequence ID" value="KAG2438262.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T3H2"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="80"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2438262.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="175" mass="17775" checksum="25D48153981F772F" modified="2021-09-29" version="1">MADQGGAGPSRPPGPQRGRDADEEERDATCDARRKQRLEVLKKYQEQRRQQLQAQLQAQLDAQEQAEWAAALAVDDAALAGGGEPALGLDTSGATSGGAAGAAAAATAVGGAGAAAAQLSLQQAGSDPSVRGNQREASHDSSSVNAQGHVAMPSAEAEAQPQPQAQPQPQPQPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T4L7</accession>
    <name>A0A835T4L7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_012948</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000067">
        <property type="protein sequence ID" value="KAG2432375.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T4L7"/>
    <dbReference type="OrthoDB" id="1099063at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001547">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF62">
        <property type="entry name" value="SERINE_ARGININE (SR)-TYPE SHUTTLING MRNA BINDING PROTEIN NPL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="20"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="118"/>
            <end position="198"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2432375.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="271" mass="30318" checksum="2DCC03464F9A217F" modified="2021-09-29" version="1">MYGGGGGRYGGGGGDRYGGRAIFVGNLPYDVREKELDEIFYKFGRIRMIDIKKPARPPGFAFVEFEDPRSAEEAARRRNNYEFAGMRMRVEIARGGEAAGAQQPLRIGYRPIRNTAGFRLYVKNLPRSASWQDLKDFVRRVCKPLYTEVFKDNRDNILGVVEFESKEDMKATLRKLDDTEFANPFDKGHYVRLTEDLEDRGRSRSRSRSRSRSRGRRDRSRLKCRALVARWSGCCGPGAGAGAGAGAGAGLRWVEWPGPAIVGCFVACVGD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T6Q0</accession>
    <name>A0A835T6Q0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methionyl-tRNA formyltransferase, mitochondrial</fullName>
            <ecNumber evidence="1">2.1.2.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_010611</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.1.2.9" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000040">
        <property type="protein sequence ID" value="KAG2439733.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T6Q0"/>
    <dbReference type="OrthoDB" id="10268103at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004479">
        <property type="term" value="F:methionyl-tRNA formyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd08646">
        <property type="entry name" value="FMT_core_Met-tRNA-FMT_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12230">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00182">
        <property type="entry name" value="Formyl_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005794">
        <property type="entry name" value="Fmt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002376">
        <property type="entry name" value="Formyl_transf_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036477">
        <property type="entry name" value="Formyl_transf_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011034">
        <property type="entry name" value="Formyl_transferase-like_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041711">
        <property type="entry name" value="Met-tRNA-FMT_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11138:SF5">
        <property type="entry name" value="METHIONYL-TRNA FORMYLTRANSFERASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00551">
        <property type="entry name" value="Formyl_trans_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50486">
        <property type="entry name" value="FMT C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53328">
        <property type="entry name" value="Formyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Formyl transferase N-terminal" evidence="4">
        <location>
            <begin position="237"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="449"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="587"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="124"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="475"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="587"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="611"/>
            <end position="624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="625"/>
            <end position="636"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012261"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00014185"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00551"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2439733.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="636" mass="63380" checksum="7FF9C0ED8B4C87D0" modified="2021-09-29" version="1">MGRPAAAGAYWRVACWASLHANAGVFFSAPAASLLGAQGWFRRLGTASPPTTGTSSSSSSSSSSSSASGQVALSAGQKQRILFLGTPQVAALVLERLLEASRLPGSNFEVAAVVSRPSGRHWLERERERERDTAAAERERTAAGAVPAEAEAMAGAGYDGSPGPLATTAHRAGAGDIAASGGISRMGMGVAAPSAPAAAVAAAAAAVASGRAAAAAAAPNWSRHGASAVERVAAAAGLPHDRIMCPVSAKEPGFLAALAALQPDLAVTAAYGAMLPQAFLDLPRCGTLNIHPSLLPRYRGAAPVQRALQDGATVTGVSLVFTVLKCDAGPVLEQQQVPVPPDVQAPQLSEQLFALGADMLLRHLPAVLERGRAAAEAAARQDEAAATYAHKILRQEAYLDFRLSAPRLHNTVRALAGWPGARATLLLEAKGTGTRDPIEVKVLRTRVASPDQLPVHGRTRVSAHATQQQHHHHATAAPSPSASGGSGSTAAAAPAAATSTAAAAASAAAATSPLPPGTSAQVVVTPAGELLIPCGDGSLLQVLEVGRRGGGVGAAASPSKTLTAKEFVAGLARRRLYVPLCTGGGRGGGGGGSGGSGGSGGSGGSGGSGGSSSSSRDGSSNSSRDGSERQADAARV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T7Q3</accession>
    <name>A0A835T7Q3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">LysM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012704</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000063">
        <property type="protein sequence ID" value="KAG2433160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="529994at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.60.10">
        <property type="entry name" value="Cyanovirin-N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036673">
        <property type="entry name" value="Cyanovirin-N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="LysM" evidence="2">
        <location>
            <begin position="152"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="127"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="205"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="465"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="841"/>
            <end position="869"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="918"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1069"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1200"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1287"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="209"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="244"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="468"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="841"/>
            <end position="866"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="942"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="952"/>
            <end position="966"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="967"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="977"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1072"/>
            <end position="1098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1208"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1294"/>
            <end position="1314"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51782"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2433160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1340" mass="139604" checksum="5E2A0A15FAE78800" modified="2021-09-29" version="1">MHACARARRYGITLGDLWAANPQLDPTTRPQLAAYNGTELIIPQMCGRPSVQPPVSTISAACTRFWPPPNTTVTGTETCGTVARSFLSNDLPYLNSINGGNCPSAATTIARGMRLCIAPKAAVVASAKGRHHHRRRLQQTSSDRNPAAGCSLNFTVPLGGFCDGIAAMYGIPTATLMEWNRLNCNELQVGQVLCVAKPGYTAPLLSTPQAPPLPPSPPQPPPSPPRPPPRPPAPPAGRWNAAQPPSPPVSSPPPTPPPVPNPPPRAALPVPSPPSSGVPPPPSPRPPRFPPRPPPAPRPPRPPVPKDDADVCVTTPWVCGPEPNNACVPVGWAQSERGYACECGAGFRRSADGATCVQLRDVAIGRPIFVSPFLEWQSVDLGSAYRVERVAVTLEADGLTPALLSSLEVRVGAAVIDGDGAIDLLLYGKVLASNPLCWSAAAAAPPVHASGSRLDVACAMAAATNDTSSSSNSNSRGGSGSSNNVPRGDSFVGRWLSVSSRSGMDTRVRQIAVYGTPYVPPPHSSSSGGGAVVRADESATAVATGPADKPHWADWVPEPQDGVCPFGYYLATPSSAGNTTSTGTTAAAATATLAASPAPPTSSAPRCARTPNAALGRVDEVYYGVRYGVTTGAQVRVGDRAVTAATVFDNPICWVNLYNIRTDDAAFRTFVSSRMSVVDARCIVPRPGRWVSLWGPDNSFRASEIAVYGTPLTDLMPAATPGGGAVPPTAAATTLPPPNLLSKFLAYRNCYIYSTYELKLPAGLNGLEEMALACVGNPTCLAFQDDGLVLFYTAVRKEDILCHDDEQLISSGPLFEPNWRATVYVKRAVAASLDVAVLPPSPPASPTPPPVPPPPPAPPPAPPPQPNAGRCDKPSWWCSGTNQVAKQVFCDDDRTLDWICVEPSTGKRGAITSKLSCASDDSRTGWPNAPSSLCPSEFGTASPPPFPPPVSSPSSLVRSPPQSVSSSPPPFPPPVSSPSSLVRSPPQSVSWRCDKPSWWCSGTNQVAKQVFCDDDRTLDWICVEPSTGKRGAITSKLSCASDDSRTGWPNAPSSLCPSEFGTAASLDVAVLPPSPPASPTPPPVPPPPPAPPPAPLPQPNAGKLPISVPDTVAVSLCPAVVDKPGRCDKPSWWCSGTNQVAKQVFCDDDRTLDWICVEPSTGKRGAITSKLSCASDDSRTGWPNAPSSLCPSEFGTASPPPFPPPVSSPSSLARSPPQSVSSCPWAGDPSSVGGSYAGSCSSCTVSSSTATAPCTLSCYCRDGSGYTRYSSLPLASCASKLVDNNNGQLTCRVEPPPRPAPPPPPPRSPPPPPCSSHKAGNDDAAPPPIDHEPDDSLPCT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T7S1</accession>
    <name>A0A835T7S1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_006535</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000041">
        <property type="protein sequence ID" value="KAG2439006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T7S1"/>
    <dbReference type="OrthoDB" id="423559at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="582"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="371"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="589"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="643"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2439006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="663" mass="66725" checksum="C6058E422F26F789" modified="2021-09-29" version="1">MLIVSNPTPAGCMHTPVSVHEQLGHLAHSHRLLCEGLLMALHDDPHGEPATITTTLLAMPIMWRQRSCPACTAGMPGWSRTLTARSLASVASFQLVRVVAASRPASWALLHGVMLRNSKAALEIQQTRHTHTHTQDMVAELSGVERAFRDVPKVRGTTAPMAERPRLSATGPIAKKADKASGTAAAADAECTDSASAGGGALAALVTQLQRCKLVKAHGNDGSIVGEHTPGTAAFGRRWQRLELDALRLRSYLACLQVPMGALQLLGAQALGRPPGGAGGGGAVAAQKRLKHRRRDLHVAAAEAVAVAKAQLKSAAESSGVDATAAAVVVAVAVAVVVAVAVAVAVVAAGGAGQQPAAAAAEASGRPNKKQHVDAHGNGNKEGEGAPAKTLLKEYVRLQDKVKYMARSEEKAKEALAAAKTGNMTAEETAAAGAAVAAAAPADATPEVAATAAMIIALKDAINKRREELGLGSQEVWLMNAELRRSIRVPRGGGGGAAAGRVVALCSGLVGGRRGGMAAAARLLAAPPRRAAHRPGGGTAFQEALYRCEPMVREKYSALNHLITQQADLGMVGDLPKAAEAAAAEADGGSDGAAGGGGGGAEDGPGPSGSGGAVADGAEPGADGGPSGSGAMPNGLGKGAAGAGTAKAAAATKAPMSVRNEHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T8R9</accession>
    <name>A0A835T8R9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000057">
        <property type="protein sequence ID" value="KAG2434490.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T8R9"/>
    <dbReference type="OrthoDB" id="543907at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="231"/>
            <end position="254"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2434490.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="254" mass="27285" checksum="1C18BD67F9852D58" modified="2021-09-29" version="1">MSTGAAATTAPLPNGDDNDGRYTLGHYYGSTKKVKVPELDHNARRRQRVIAEIVEAGRRLGIKEDVIRTNLDKMEALLPELTPDVNKMRAAEWAKLARDVNQVAMMLVVIKTSYPGANVGKIVSRAPKTLLQSPEQLQADAAVVRKVLAGAPNADAIIEEVPYLMSPPALAQSLSNVSRWYNTKDPVAMISKNPKLLLNVEEADLEADPLYGLSLNLSTIDTWDFGLQKVGGDGDGGEAATAAPAPAQPQPQPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T923</accession>
    <name>A0A835T923_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PARP</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_011751</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000051">
        <property type="protein sequence ID" value="KAG2436039.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1669894at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd11709">
        <property type="entry name" value="SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.920">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.40">
        <property type="entry name" value="SH3 Domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001870">
        <property type="entry name" value="B30.2/SPRY"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043136">
        <property type="entry name" value="B30.2/SPRY_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010606">
        <property type="entry name" value="Mib_Herc2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037252">
        <property type="entry name" value="Mib_Herc2_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13857">
        <property type="entry name" value="Ank_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06701">
        <property type="entry name" value="MIB_HERC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="21"/>
    </dbReference>
    <dbReference type="SMART" id="SM00368">
        <property type="entry name" value="LRR_RI"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF159034">
        <property type="entry name" value="Mib/herc2 domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="13"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50188">
        <property type="entry name" value="B302_SPRY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51416">
        <property type="entry name" value="MIB_HERC2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="1123"/>
            <end position="1155"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="1159"/>
            <end position="1191"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="1227"/>
            <end position="1259"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="1494"/>
            <end position="1526"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="1531"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="1565"/>
            <end position="1597"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="1785"/>
            <end position="1817"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="1818"/>
            <end position="1840"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="1991"/>
            <end position="2023"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="2025"/>
            <end position="2057"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="2198"/>
            <end position="2230"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="2272"/>
            <end position="2304"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="2314"/>
            <end position="2346"/>
        </location>
    </feature>
    <feature type="domain" description="B30.2/SPRY" evidence="7">
        <location>
            <begin position="2554"/>
            <end position="2735"/>
        </location>
    </feature>
    <feature type="domain" description="MIB/HERC2" evidence="8">
        <location>
            <begin position="2746"/>
            <end position="2816"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2132"/>
            <end position="2175"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2428"/>
            <end position="2463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="2760"/>
            <end position="2780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="29"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="72"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="112"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="2428"/>
            <end position="2450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50188"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51416"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2436039.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="2816" mass="287032" checksum="475651DDDA20E3B7" modified="2021-09-29" version="1">MADEAAEAQQGGAGSGGGLGAGGAPAPREVNRAAAERQMRKQRLAALLTGKPSATASPAGPGSGADSEVEVPGTPTAAALADAAPGGTGSASSGALTPNAAAHGPLPPKPPVSSSAAATPALPATSSLQRAPVAGGPQAHTQPQQQQLPPPAASPLGAWRPGTASGDWAHGSPDGSSGFAALGTKPGAPAPVASVSVAQGGSGAAAVRSGGGGGGVDVIWRDKDPRVLLKELTDAVMLYGGVRVLELNEPKFIKRLQWPQVLECLLLSGSPPARVLIPQLSSVREGERPLVAAALQLLRSARHTAAADATDAARGGTGGDSMIGVLGGAGGGGGVDIVTDMDEELEERVMRFHEERDVAELGRALGNTLHHRLAGTTPVPEGPRQLVLDLQRLGLTRAQLSELLEAAGLPHPTARSVKHPYDCAAVVTLLDVSGNALTDRIAADLLLLALTSRTVHRIRAVGVQMSAAACALLAVVVAHFRARGLSRVELDLGLDPAAAAEAAAAGGAGPGGGAAAGGAVPLSAAIAGSQREEWVACWFTCLDQVVIATVSGGELPPAGAVTAAAAAAAAGAAAGMAALMRSQTLNRGAQLTSLMSMVRGRVVGTSSSGAPIMPGASASGVLGSAGGGRRGAGDAAAAGAGAGVGAGVGMGFSAAPPVPGGLQLLQALQRPAPEGLGDWLRPEELAAAVCLLDPSRCSTLELAGSSREAPVLLNEDLTGRIAHRIVAWSLPLTRLMLSCCAVDVVVLRSNNAIRQLTKSLNERCALTDLTLREVTFSQPAALAELLNCIRSDTLQRLDLYGTDCGSTAEGVAALAGRLAKCPALTHLDLRQCGLKVSGAAALVGALPGCPALRSLDLSHNAMQLGGGDVAAFARALAAMTALTSLQLEACKLDHSCLEELGRELFTPHADSPLPLQVLKLADNNCRGAWLSGIGRALERLTVLDLSSCSLGKSCMGCLAEVVAAGGLPRLASLDLHSNITMDDEGAAVLVAALAGRHQVLGAPGRLDLRYNNLSGDAVAGAAAALWDGGLVSDLLVEDQVLATTAGAASEYSLSELFRAIVDKRPEEKVPIILSKTGVDILHDKRPHDGFTALHMIAKRNLMPLAAIVSRFQQGVDWAVEDGLGATPLHWAAFKGHLEMAMLLLAQEGSAGWLDAPAKDGATPLMLAASAGHRELVAALIGAGASIHRRNRGGFSALHLALASPSEAASEVVVCLLEAGAHYGQKCGGKTPLHLAVTYGKVKAVEALLVRGADPLVPSSEEEEGGSSSGSGAGVSNVLPLELISKAGGGGGGGGGGARKVRVMSASANTDRMEHVLAEDSNTWKSGSGNSSALRHFLLFEIPEGLNVEKIEYRSVAEHATDDGGYWPHAWRVEAGANASSLNLVSESRIDPPSRKQDFSAPISGSLGANVRYVKLWMHNTRQGNVITVNQIAFKLRPALVLAAEVSPEDRQAMAEALEAAMLAASAHAAAAAGKAEALVALLDRGACLNRLDLKGRAPLHYACEAGNVPLAALLLARGADPNLPTGPPAREAYTPLHLAALCGSLPLVRLLTKVPQVDINATSSRGYTPIMLAAVAKAGPVVFLLSGAGADLEARSKDDNSLAHCVVCPAGDFSLLEQGAMSKKAGPPRQGYMRGVLASLADVGSIINSPNAFGYTPLDVAAIAGDKLGVKLLSEAGYKNTHFGWAALDDSVNLPISDWGDYYTSSGGYGYGGGYGGTIFYSGGGYGGGYYAGGGGAAKANKAKQAVATSRHGWTPLHAAAANGSSKVIAGLSRKYSVHLQDTLCGNTPLHLAALAGEAKAVRELLFDRASSNTANQEGNTPLHLAAQSGNSAAAALMINSHISPCDPNTPNKDGRTARDLAAASDCLQAMGAALAADGGTGGGGGKSSAARNVYYQRQQPRHSLTWAVENDDLDEVSAILDLPGLNLKDVDPNTGLTALDVAVRCGASGPVAALLRARAVRHSLHFAASDATRLVEAIAFWKDVDMANGNGQRPLHVAAHEGAADCCRLLLEAGAGVDAASPVSGVTALHVAVEAGHGPVVELLLAAGASALTKASKQTRLDAKGVSPLQLAAALPTHKLRRELTSLLLGSLEPPSEEARVAVAPAAAAFLKLTASASTVSRAVPPAAGLSAGASGSSVGSKGVPAAAVGAKRPQGTGAAAPATTGGSASAGQQHQSLVARVGAVMGAEQAEQVRGALSAALRCAVALADLELVQQLLRLGADPNVQDPDTQYAGLHLALTATPRPEPGTTKSLVAALLAAGADPLLADSEGTTPVHLAAGAGALPLLEALLAKAPPAAAANGRVADLPRLTDLATPLLMAAAGGHLPVVKLLLGRGFSGDLMRRRRDGTHGLQLLAPHVSALRRLGVPVPRWTSPGADLVDAGTGLEAALVALVEEPGSKRRVWSAGVPSNWLLLDTWAHCGGGGGGGGGGGGSRAAGGGGGSGGGGEGQEEAEVVPARLPGGPSRVVRVSVLMHKDQRKTAPVRWTVLTGRSPEHLAERVAAAELPDGAHGWTDLPLPEGGLPAHRYLKLVAHPREGEQVQVCALSVGVAAAAEDEGAKEEAAENVEPLSFEWSPALMHEDVKLISPVCATKEKNGDRYSTVMVDVPLDAGLHEWEVSVDTMAGENMFIGLRAVDDQLDRDAGQVDEERRTYYLANGKVRVMGKLVSDSTRFRTGDVIRMELDMDAGGAISFYKNKELIGKGTGVEKGMRPFVCMERPGDRVTIVSYNGSGTSQKVVSEPTVEATVTQETAAKGMKVQRGPDWSWENQDGGPGKTGTITNVKGDGWAEVKWESGSTNSYRVGAEGKFDLKTVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T9S9</accession>
    <name>A0A835T9S9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_006620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000041">
        <property type="protein sequence ID" value="KAG2439098.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T9S9"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="181"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2439098.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="193" mass="19582" checksum="BA0626CC404ABB71" modified="2021-09-29" version="1">MQARAATSASGPSLDDPNNAYIDKGLTVQGAAEGPLKGLTFAVKDLFDVAGHRTGFGNPTWLETHPPATRTAPAVQALLDAGATLRGKTHMDELAYSLNGENKHYGTPRNPAAPGRIPGGSSSGSAVAAAAGDVPLALGSDTGGSVRVPAAYCGLFGIRPTWGRTNLEGARPLAPSFDTAGWWVGGLSGSGME</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TBG3</accession>
    <name>A0A835TBG3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_010177</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000037">
        <property type="protein sequence ID" value="KAG2440597.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TBG3"/>
    <dbReference type="OrthoDB" id="542825at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <keyword evidence="8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="407"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="575"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="455"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="663"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="795"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="969"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="663"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="798"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="602"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2440597.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1042" mass="108265" checksum="7F51E76EF47C0E5E" modified="2021-09-29" version="1">MARKVVIPPLGEVRLRHFTARNTRRGGGGEIDFIAYSPKGILWTDDLNKNQIICLHSDPSKLIPLPLPVGFPQFAGQAQNVSLWDSYCASGRCWNEVLHYDQFSTDVNVGSDSETGGYVMAKVNSSKTCDAFVEQPCIDSKGGEACMQAVISSFLASLPPADPAVVTSDRQLFAAICAQNPLILLGADLDLREEHWPANCSAPVKLVRNMTISGPLDAPIKYTINFNFMARKVTIPPLGEVRLRHFTARNTRRGGGGEIDFIAYSPKGILWTDDLNKNQIICLHSDPSKLIPLPLPVGFPQFAGQTQNVSLWDSYCASGRCWNEVLHYDQFSTDVNVGSDSETGGYVMAKVNSSKTCDAFVDQPCIDSKGGEACMQAVISSFLASLPPADGTSVSTDSGGDSGGVNVLAIALPVALGGAALIGIIAAVGVWAVRKRRRGAEAAAAAAKLGDLESSGGAGGYGRRNSGGELKKGSKGGDSQSSDSKDHHNSEEEMGVYAPHRNGQGHGHERPHDTIASSFRYETGDDMGRCLVVNAAAALGGVAGGGSGAGSVAAGSASGLAVVEGVMDDGSVCALTVGAALGQGSFGVVFRGTWRERPVAVKVICCERQHAEQVASEVRLMMSDACRHPHLLRALACMSRTRVLNTRMNQAASALEATLNTLGSRARSRGSAGPGSSQQQRLGASGTDSGPINRESGGNAGELVETWIVSEYCDLGALAPHVHVAKKFLSPPRPGGGGERRPQLAPILSCLRDIAAGMAHLHSLNVVHGDLKLANVLMASPRCVAAAAAAEAGGGAGTAASASPDDSAAVSSENNVVTDSADASVWSVSQLPLPAGFVAKVADFGLSKALKEGQTHHSTKTVGTVTHQPPELLRSGKLTLSGDVYSFGIMAWEMLTGSVPYKGLMYGEVVERVVVSHRRPEFPPHTPAAYRALAERCWAAEASARPTFKEVLAELEALLAAAPQLQAESDSVALPPPTASSSSAVPATTTTTTTATTTAGALNTPSGGPSGVPTSGGVTSPDSATITAVAAAAALEDLTPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TDL7</accession>
    <name>A0A835TDL7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009940</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000035">
        <property type="protein sequence ID" value="KAG2441348.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TDL7"/>
    <dbReference type="OrthoDB" id="540503at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31535">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31535:SF3">
        <property type="entry name" value="REGULATORY PROTEIN ZESTE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032706871" description="Nucleotide-diphospho-sugar transferase domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="653"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="869"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="900"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="934"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="945"/>
            <end position="957"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2441348.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="967" mass="102386" checksum="FC3ECD3B8535A58C" modified="2021-09-29" version="1">MIVLVILAVALTCAKPGLALLPCERSGLCSIGKTAPYVGNVDSSAGLRAALEARSFKREVILMSTDSEQLLPVRQAVHNLLRLGLEHVLLMSASGPDCVRVAGAVPSAGCVWLDFELPVFGADSAAVPTAAPMWHNRYRLAARAVRLRYNTFIVDTDAIFFDDPYVYFKSPPFADFTIINQAEVLYNQDDYVSEVRPNGGVLYIQNAAPDGPAAWLLAEVTDRLLRWIEDGFNTTRHTHDVLTWCNYMDQDGLRDAISSVMMGTMFFASAMRDCRVPEWVQQHGPEYDAINYAIIYRMGEGPGEAFMKTEHVQLPPVMRPAAGGESQVMIRHFAMSQPAYTPWNASYGPYLYPASRGVLSRQWLSQLKEDCGCDLWPDPEDPSPAVVAAARATPPERYLLAPPFLLGNWFSRGRFGFWNRALSPAGPQQVVGHLHYIPDTDTIVSKTVARMAAGQFDWLLAAATPASGPGFGGGGSNLYLLMRGSRTTSMAPSLANSYAAAGGALGGGGGSCGGGGGALQAGSPHLVAYHPQLLADLAAAGSWRDYSALLVALATAAEAMGRVPVWPDMPCSASWVADRGPQHASSLPLDIRTEWVPYGRRRSRLMCCWHMLLHEACVAGGRGMLALEFAHWMAGARLQYPVEPGAHNTVATLAPETPDGADRKDATRGSSSSTAADAAKGIRPVPLPSGSSASAAAAVSRELSWWGQQAAAAAAGEGAEAAATMAAAALEAEEVGPGVGTEARALVGASSGGGGGEIRAPRRKRFQVYSVAREEVVLAWGIRATFAHRVLYLRYPINVTFAPGSDASWALGNTLNECRATNPLAIQESLANKPFDNTTATDLWVDFVPAAIGGAGGGSIRRSAAIPGYNVPDHHVEPAASGSSSGAEDGRSGSSGSGADGSSSSSSSSSSGADGGGGGSVNGDSSPAANGNSKDMRIAHGEKVPQQQQQQQPLMPLLERRRRRYHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TGM4</accession>
    <name>A0A835TGM4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_010816</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000043">
        <property type="protein sequence ID" value="KAG2438360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TGM4"/>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050490">
        <property type="entry name" value="Bact_solute-bd_prot1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43649">
        <property type="entry name" value="ARABINOSE-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43649:SF12">
        <property type="entry name" value="DIACETYLCHITOBIOSE BINDING PROTEIN DASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2438360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="84" mass="9236" checksum="BC8EC46010019A32" modified="2021-09-29" version="1">MLQLANVCGACVVYRETVAVYEGKVVGLPTHGLVVHLYYLRDLFSAAGLRPPRTWDEAIAIARRFNGTDLDGDGAANDYGMCMW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835THS5</accession>
    <name>A0A835THS5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_010179</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000037">
        <property type="protein sequence ID" value="KAG2440599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835THS5"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000005">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.10.25.10:FF:000038">
        <property type="entry name" value="Fibrillin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052080">
        <property type="entry name" value="vWF_C/EGF_Fibrillin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47333:SF4">
        <property type="entry name" value="EGF-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47333">
        <property type="entry name" value="VON WILLEBRAND FACTOR C AND EGF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="8"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57196">
        <property type="entry name" value="EGF/Laminin"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6 8" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0964">Secreted</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="62"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="102"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="350"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="9">
        <location>
            <begin position="390"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="8">
        <location>
            <begin position="66"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022536"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2440599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="561" mass="59349" checksum="E3B7AE0C9DEE4FC0" modified="2021-09-29" version="1">MAPAVPADAPTAAAVARRFRCRCRRHSSTTTTITSWAAAVAVLCLAVAVSVAPRGAEAIDVSFNPCILSPCGIHTCKFLGSNSYNCTCLPGYTNLSPTQCVDIDECAGRTRICGPGGDTCTNLNGTYSCTCKPGYKYNTATKYCDDINECNASPGICGDALKHNCTNTPGGYACSCKKGYADTVTNVLTGAHTCKDINECALGACASNGTYTCSNTEGAHYCNCKTGYQSGPPITNASLLLNDCLDVNECSLSPYTCRYPDGRPETKCINYSGSFTCNCTAGYKTVDEGSAVSKVCKDIDECSEWEDKVCLTGTPHWPIPKCNNTIGSYKCNCVKGYTEALVNGYKTCVDVDECALGACGNGSASCTNKPGSYECKCKAGYTFDGITCKDKNECMEKPGRCGTGGVCVNKNGTYSCACNATYVSVSTGRNGPTCTKDICGILKPCGLGKCKNVPYDKNTCKCKTYPPGYDGVKQDTEKYTAADKVQWCVDNTCATFGTNTTTHPCKWGKCFNVRSPLGYDTYDCECKESQNLVRKVVGVKPYCEQINIIGSGVGGGGVIVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TJ72</accession>
    <name>A0A835TJ72_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_010661</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000040">
        <property type="protein sequence ID" value="KAG2439785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TJ72"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="122"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2439785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="305" mass="34002" checksum="1654455F18703E62" modified="2021-09-29" version="1">MAAIAEIIAAIEKVEAETQEAGVAIKAVESKIEAVESVIEAVESKIKAVESDLQNQALSAEDKTALRSTLDHLRKKEQQLRTEKEQLRNKEQQLRNKEQQLRTEKEQLRNKEQQLQEQLRTERERLEEEGDALLEGFNEYIKRVRILNGPSQTSLKREQRDPSSPLVKNWRPTTAATVGLLPELAHPQFAVAVDILGGGEELDQATIDAADRLCCIGADIFDNEARLTDEVRGVLESYLEDDRAFPITSGFAVNNVKPDWSLGDASQSPSNLFLVVEVKPGLGGTGDSHYQGALYQMHFWAAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TJV9</accession>
    <name>A0A835TJV9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">mitogen-activated protein kinase kinase</fullName>
            <ecNumber evidence="7">2.7.12.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HYH02_010455</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>L-tyrosyl-[protein] + ATP = O-phospho-L-tyrosyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10596"/>
            <dbReference type="Rhea" id="RHEA-COMP:10136"/>
            <dbReference type="Rhea" id="RHEA-COMP:20101"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:46858"/>
            <dbReference type="ChEBI" id="CHEBI:61978"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.12.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.12.2" evidence="7"/>
    <dbReference type="EMBL" id="JAEHOD010000039">
        <property type="protein sequence ID" value="KAG2439821.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TJV9"/>
    <dbReference type="OrthoDB" id="10252354at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004708">
        <property type="term" value="F:MAP kinase kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd06623">
        <property type="entry name" value="PKc_MAPKK_plant_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000432">
        <property type="entry name" value="mitogen-activated protein kinase kinase 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013">
        <property type="entry name" value="DUAL SPECIFICITY MITOGEN-ACTIVATED PROTEIN KINASE KINASE 5-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48013:SF32">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE 2-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="134"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="33"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="229"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="290"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="76"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="92"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="102"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="240"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="294"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="binding site" evidence="11">
        <location>
            <position position="163"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00038035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00038999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00049299"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00051693"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG2439821.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="510" mass="51528" checksum="3DB74FBAB261DCE1" modified="2021-09-29" version="1">MQRRLRPEPIAVPEEKKASYVLTNKGKFVEGDLTISREGLQINSPASTLGAAPRPGSASSLQPNKRPLPPEEDSASSRGSGEPSTSGAVAAGGSPRPRIGSAGPGGGAAAANGGGAGGGAGASSATEGLTIDDFEELCVIGQGSSGVAKKVRNKRDGRHMVLKVIQFDVSSDTVRKQVTTELRTLYGADHPAVVRYYGAFFDNGAITIAMEYCDAGSLADLLKARAKQYQQQQHHQHRLASCSRPPAPSGSAAGAAVAAGPGSAAAGAAAGTSNGGATAAAGAAAAVGESGTSSGAGAGPGSAAGAAGGARAGPGLPEPVIAHIARQLVAGLTYLHKELKVVHRDIKPSNLLLNGAGEVKISDFGVSGQLASSVSNCLSWVGTVTYMSPERIKGDSYSFDSDLWSLGLTLLECALGRFPYPPPGETGVNLGFWELLEYIVMEPPPALPADQFSPALCDFVGQCLQKDAAARPSVTALAAHPFLAMYLDASLAEVLEPVLGAQGGAKGAGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VMY3</accession>
    <name>A0A835VMY3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_015392</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000193">
        <property type="protein sequence ID" value="KAG2422787.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VMY3"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43289">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE KINASE KINASE 20-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43289:SF6">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE NEKL-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="60"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="590"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="672"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1026"/>
            <end position="1048"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="594"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="616"/>
            <end position="626"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2422787.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1083" mass="115184" checksum="3035482836BD7754" modified="2021-09-29" version="1">MAPKQKGDAKVSTAASFDVPLPPAADLDKSLIDGDNAEIIVTVLAIVASDGARLHEVIKRYAPKHSFEGGQGKIWKVQLQPRLDPASQLVLPVIDMRAGPDKKMAKEGLSEEQLKTKLLGTPVPGMLKLIWTRYEQTGQILDLARNIIVQAVLSTGALGFLVQRLIRVSVTPVLKKHVAAQLRLQGGVAAGGGKGTDKVQAAADSIEGLLATQLAPQQDGSMADGLRSIAHEYLRQVKLESHADMLARAVTYKTLPPVHENLVEDWMRIGTVLLMILDAMDQANVVHRDLKPANFLMSIMDGGTWMATRLADLGLARMVVDSQLNLTPGLLGTPGWMHILRCLWKAVFGEDPIRISDKEMDRQCGGKVLLSMPLSGELLQRHPISLGVGAFRYMLSWFSTEYLLPCDDRVGYGNAPVQLLGIQFALDLYLVGGTSQELSEALLLLTLSQTVSEQPQGRAVFATRAASTGEYLQRSEALFEECRPAWEAHAAKRRSMPTDAILDGRVYNAKQRLSEATALVREILGLCAVPQEEMRDRRVQAAVEQLMQRQRSAATLTCVGSGDGLQLKVAWVNVEAELRCIRGTFGGAGGDGTAGRQQQQQQQQHCRPADMVAPGRDAEEHEAHEEREEDEEDELWLRKLAVDRGDALSPLHHILAGSDAAVAEAAARKAAGGGRGVGRQRGPWQPGAARGRYQRGGSRWQHDSRLLFASWMAAGNLLFAGPTKAMSLDIANSLPTAERAHVLVEMGFMSKQQADRLDKEAQKKLCFSLTCLMPALVSYANHALTQSMSIAAFLQQHPRALAVSLRGQQQAAAVRPAVAAGAGAAAAAAARPAGPAAAPPPLAPPPLAPAGRRGRGALAPVALVPRKAPGEIAAGGRPGGVVPLAMAPAPCQGAAPTAMPAAVRGLGGAAPTAMAAAPGAPLLSAGPDEAGMEEAGPEEAGAVDAGSEAEEAADAMAANVVMLLVHAAIQTCDSEQALKLLIHKLAAFNTQDLREIEDPASPLVPTLLQAAQAAQVQQACGHAVMERAPPQPGQQGLAGLQGGPTSEPPMPQLAATMERKRQCPQEDVEMEEAVQPLQYWKKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VSC3</accession>
    <name>A0A835VSC3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015242</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000130">
        <property type="protein sequence ID" value="KAG2424063.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VSC3"/>
    <dbReference type="OrthoDB" id="548283at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="79"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="157"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2424063.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="260" mass="26341" checksum="7B980489C205C03B" modified="2021-09-29" version="1">MRATSLPAVSPAAVRAQRHAALAQTLVQFVARLPPPSPGSPAEALRSRLGARLSVPALGEWIRDFTAALVAGARDQATAASGGAPSAPPSSGAELQQPGQGEDLALHPELHEELERAVERLLSSQPQLLAHDSAVLVARLRGLAGLLQLQVLRQAGAAGGQGQGQGSDTAPAGRGREPGAGAGVGTGRAVAAPSPTAPTAPTALDLALQRPALLLADLPTLERRLAALQAALGLPDREAAVAAAVRAPVWLYMEPPPPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VTD6</accession>
    <name>A0A835VTD6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">PEP5/VPS11 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000092">
        <property type="protein sequence ID" value="KAG2428577.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VTD6"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057307">
        <property type="entry name" value="PEP5_VPS11_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23341">
        <property type="entry name" value="PEP5_VPS11_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PEP5/VPS11 N-terminal" evidence="1">
        <location>
            <begin position="6"/>
            <end position="86"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF23341"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2428577.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="110" mass="12096" checksum="0CDD843483D55787" modified="2021-09-29" version="1">MGFAFKRFNFFQPHQVARHAFPPNASCVVPGGPVLWVGTESGSVFILDARLSLLGTFNAHGHRVLEVVWLEKRQLLITVGSEEPGCLPFPCASREMHGVPRLVLVRAMAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VWJ7</accession>
    <name>A0A835VWJ7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF7798 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_013083</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000069">
        <property type="protein sequence ID" value="KAG2432012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VWJ7"/>
    <dbReference type="OrthoDB" id="546800at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056700">
        <property type="entry name" value="DUF7798"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36011">
        <property type="entry name" value="BAT2 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36011:SF1">
        <property type="entry name" value="BAT2 DOMAIN PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25074">
        <property type="entry name" value="DUF7798"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF7798" evidence="2">
        <location>
            <begin position="496"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="631"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="778"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="875"/>
            <end position="973"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="116"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="139"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
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            <end position="172"/>
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            <begin position="359"/>
            <end position="376"/>
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            <begin position="1"/>
            <end position="105"/>
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            <end position="227"/>
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        <location>
            <begin position="531"/>
            <end position="550"/>
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        <location>
            <begin position="90"/>
            <end position="105"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="207"/>
        </location>
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        <location>
            <begin position="403"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="SAM" id="Phobius"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG2429658.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="550" mass="55692" checksum="47AAB45AF66C93B6" modified="2021-09-29" version="1">MQLAPGAVSGAGLPTRRLRSHTASPTPFAHRRCCVAHASRDKRDGPGRGSGPGYGVAPPSQWVLPKVLVGEPRPASQGAEQRVGSPAEQAAPSGTPSSSSASISANPPLTVYTVRFTTGTSRGAALSDPYSAVNVCLIGANGRAALHRVSPVNDPVESRAHTAEMCQLIDSEVGADCSAFVPPPPPAASGSSSPAPSPASAPPPPPASSQSAPLVGRPPPPAPPKRRFQEGMVDEVSFLVPELGPLSGVLVGVEAGAWYLDEMDVSSSRTGHMDRFVCRRPLGGKVGEGAALLTPVPVGAVVYGEGEQAVVLTKDQAAALWSLNMNDYTDLKKRLAATTALLVASGASLAALTGGTAAALPYAAGGVVGLMYQWMLMRGVDHVMVAASGSSRQAAALRGEGSGSSSSSGSGTSGVRHGVYSSGNSAKQQQQQAEGEQEPYGGREETTSSGTVSRILGSAPLRLGFVCASAALGLALLGQEEAAAGAATTGPTAAWQLFLAALGFLTYKVALVGVSLGESAASTAAAAKGVAQRANSQGANRTEFEKYKRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W4B0</accession>
    <name>A0A835W4B0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Endoplasmic reticulum-Golgi intermediate compartment protein 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_010663</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
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        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000042">
        <property type="protein sequence ID" value="KAG2438865.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:COPII-coated ER to Golgi transport vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="Erv"/>
    </dbReference>
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        <property type="entry name" value="Erv_C"/>
    </dbReference>
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        <property type="entry name" value="Erv_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984:SF82">
        <property type="entry name" value="ENDOPLASMIC RETICULUM VESICLE TRANSPORTER PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10984">
        <property type="entry name" value="ENDOPLASMIC RETICULUM-GOLGI INTERMEDIATE COMPARTMENT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07970">
        <property type="entry name" value="COPIIcoated_ERV"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13850">
        <property type="entry name" value="ERGIC_N"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="333"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="domain" description="Endoplasmic reticulum vesicle transporter N-terminal" evidence="7">
        <location>
            <begin position="2"/>
            <end position="72"/>
        </location>
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    <feature type="domain" description="Endoplasmic reticulum vesicle transporter C-terminal" evidence="6">
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            <end position="355"/>
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    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
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    </evidence>
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        </source>
    </evidence>
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            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
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        <source>
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        <source>
            <dbReference type="Pfam" id="PF07970"/>
        </source>
    </evidence>
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            <dbReference type="Pfam" id="PF13850"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG2438865.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="375" mass="40656" checksum="D92500EB450BFB37" modified="2021-09-29" version="1">MSGGIITIVSSVVMVLLFLSELRLFLTTSSAHELSVDVGRGEKIMIHFDVTFHKVPCSWLSLDAMDISGELHLDLDHDVYKQRLSKNGTPLKEVEKHNVDATKKKAPAAVNATLAGHEAGAGGENGTALATGCGSCYGAEDKQGDCCNTCDEVRAAYRRKGWALSNVDHIEQCAHDLYTESIKEQAGEGCHMWGMLEVNKVAGNFHFAPGRSYQQGSMHVHDIAPFGDAVIDFHHTIHKLSFGEPYPGMKNPLDGAKAGQATAVATGMFQYFLKVVPTSYTDLSNKTLSTNQFSVTENFREAQGGAGRTLPGVFFFYDLSPIKVKIVEHSSSFLSFLTSVCAIVGGVFTVSGIVDAFVYTGTRLIKKKMELGKFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W4B9</accession>
    <name>A0A835W4B9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_011539</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000049">
        <property type="protein sequence ID" value="KAG2436604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Phosphatidylinositol 3-kinase-related protein kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
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        <property type="entry name" value="FATC_dom"/>
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    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF124">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02260">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51190">
        <property type="entry name" value="FATC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="2">
        <location>
            <begin position="1373"/>
            <end position="1736"/>
        </location>
    </feature>
    <feature type="domain" description="FATC" evidence="3">
        <location>
            <begin position="3455"/>
            <end position="3487"/>
        </location>
    </feature>
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        <location>
            <begin position="209"/>
            <end position="275"/>
        </location>
    </feature>
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            <begin position="1070"/>
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    </feature>
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            <begin position="1299"/>
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        </location>
    </feature>
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        <location>
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    </feature>
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            <begin position="3286"/>
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    </feature>
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        </location>
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            <begin position="1499"/>
            <end position="1510"/>
        </location>
    </feature>
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            <begin position="2665"/>
            <end position="2685"/>
        </location>
    </feature>
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        <location>
            <begin position="2692"/>
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        </location>
    </feature>
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        <location>
            <begin position="3301"/>
            <end position="3311"/>
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    </feature>
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        <location>
            <begin position="3312"/>
            <end position="3322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="3329"/>
            <end position="3339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS51190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2436604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3487" mass="341625" checksum="00D4ECC2E4734F3B" modified="2021-09-29" version="1">MHHGLSRLRDLRSTQRSLLASLAQERRAAAAAASGAAGAADTAAAAAAAAAAATAAVAAAAAAAVSGRQAGGRRRGGHAGAGGSGSEADVAVAAQASGTQAASAAPASSGPGAAAAAAGAAAAAPASPAVAALETSLQRLGLAVTELLKLVGAAMLTAGEADSIAGLHVWVAREFEPLLLGAHLPGGSAMAAAAAASAAAGDAVVASGANAGSRSSRSRNGSSSTSAAGAEAVARDGAPSPSGSGAPRRRGDAGTTRTNRSGSAGSAAAGTKPPHKDPFAWLQGLRLQAAGSYESALLAYNAFLAAPQPGSSATGGGSSASSQQQQAQQAVALELAAAAQGFVVERVAECYAALSDWSGLQGLVSAFSRTAAAASAEAGGGEGGAGSAAPSGSAAAWWPPAAAAIQQRFGGLAAYDSGGGGDGGLLTSAAAQAAVSPLDVNAPLLAALHAMTAAAAGPSTAAQQPAGPSYQHQQQHQQLLQAQQEQLAAARGVVAAALGRCAAQLRSAALSEAASQKELLLRLTCLRAAARGLDQALSARSHRQPHTLPHHAHHQHQAFATWTGLLSLPTQYCSGTANDMGAMPAVSTPTMAAPQLLLGRALLAPDGLGLQPGVLRDAGLAAALLRPLRAAEHAAGGSSTSSSGGVWALSIEALRAAATGGNLGLAAKTAAALAAGSGVGAGGRAVLSVVHSLLSAYGAPGRLQPSQLVDLQLRALMPHLQPPAGVPILGAHNAGDADDLACALVTLGRWMTKAGAVYSHALQVHRQQQQQAAAAAAAVAATAAAATSPGRPAPPPGFGTAPPAPPLWQGAIDWLGLSQALLKQLGHAHHAPSAGAAVVGSGGSGAALAAFVVPEALFLGSQHAAASGSAAVPSGSAAAAAAAVTLRALQLSPGCSRAWRAWGDVLLRATKEQRARAAAAATAAACTGATAGRDFAHGAGAEGPGEVAAAGYGAAAAAYCRYLALSYSGTEPGGAARADEALPVLLQVLHIVLRHGASLEKQLQAQLAAVPPAAWAAVSAQLLAQLPSARGAARRLLAALLRAVAAAAPSLVLYPAVVEVRAADAAAAAGTDDADGGSGGGDSGSCASASSSSMVPELRALLADLGRARPGLLAGVQTLVGEMVRLTVLWDERWAALLAEVEVEISRRAVSLQAEAARVAEDSSLSPVQRQALLASRYHTLMAPAVVLLERQLRATAAAAAETPHERRFAATVLPRLRAAAAALRDPEGAAAAATVVGGAGTATPSAPVVRDWARPVAAWAPLRAAAAALSRSQRDPLPPLAELSPALAALVDTEVPMPGLADGDGSDGSGRGSAAAATSADWMPASATAPDGLPHPGDAFSAASAAAAAVAAGAGGPAYGGGGGGGVTVAGVVGQVTALATKTRPKRVALLGSDGGSYGFLLKGREDLRMDERLMQVLRAARSVLSSDADCAARGLAGCVRPYSVTPLGPRAGLLRWVPDTMSLFAVFRSWQAATLERHAAMAAARQEGAAKAAAEGAPPPPELEPPPAAATSRPMDLFYSMLVPALTERGLSSATPRRDWPAELLRAVFGRLVAAAPRQLLGRVLWAGGGSAAGAWRRQQRYARSLGATSVVGHLLGLGDRHPDNVLLEGRGGGVVHIDFNVCWDKGAKLRVPEVVPFRLTGMLVSALGAGGLEGPYRAAAEAALGCLRRRRDALVGLVDAVLSDPGVDWAVEREDAAARQDMELAVALGLFVSRAEEVQRQLAVIEAMLPGLVEGGLGAGGGGDVGLGGGGDGGGGDGGGGTGALASLLGYVEAHGFAEALRAAAAEAEQRVAQAKASTWAALEAASRSEAEARAIITAAAQEAASLAADATSVRAALPAALTQCGRWAQQHSTALSAVRDGAYLEGTIAAGGGAGGDGGAGAGSVGGGSRAASWRAAESGAALGLLSPLSVALPPAQVAPGGAVGSAPPGLLMAIVGGDGSALNQMPEELLCACSELDAKGSELLRRRETLLGGALAALEQYGVVVRKLMPYSYPASSYHHRWAAALSAVASGGLTLPAVAAAQALAPREPSPAEVLAAWQALRGSQRLATAAVMVLAPASQEAEVARAGVVGGARVAGREMAEAVAAAARALAETQAPPAAEARALAASMGVVTGSIGGGTAAATAAADLSAQLARLLDRRPAQQVDPRTAATAAAGLCSLLRSSQARLHPVLQRRAAAGAGAAAAAAAGGSSATAATAVILSDLVRLGGEAVALASAVSAAAAAGLGPSLQLLPLSAQHPHAQSRHVALPGLGGAGTAAAVCPVPWLAAVADGVGRWLELQQRLAADVAPELAGQVHVGGGGGAATSGDVAAGAAPPAAALTAAVADLSRLVAPVEEALAAGRECHTRLSALAELTATYPQRAAELAARLAAALHPAQRAATEAEAAALEAAWASRDATAAGLSAAAAGADEALVDALRRLYAAVLGPGHVPRELLTWRISDGMAAPPAFEGYAERGWGDGEAAAGTAGGGGSEAHAALSSLAAWWEAAVAAAEAVDVAAGTADPVDAAGDNSYVSSRKQLPPPMRPLWRFAAAARRTLAAAQALLRLRLAAQSGSDGALAEAYSAVLPALARGAAEVLGGALARALAAAGPVLAVQLAEAEAALRQQAASSAGAAAAALAPLPVPGSAAAAAAAGELVPFTGFDPDVAGAGELLGSLEGDDADDGIDDGGDLADEELDGGGGGDEGGDDGDSDGGLDLGLDLDLDDGFGMEEVDEHEQDIVSYGGGVAAAAVGNSTAHGAGSGGMLTAAVGTGAQQPVSDEVVARLMERLAAAAAAATAAACAGAVDPAVAAASAAAATSPAAVATTMTTTTTTTTTTTTPGGPGWIPGSAAAACRAARLHRLAALEWCREPLLATALQGDPRLGAGLAHFFAAGGAARDPLQPSARSTLPAAGFSRRAVLAALAAALRELPELERALADWEARGGGAAAQVVALLRGAPAAFAVDTALAAQRAGQLAPRRAAWVADGRALSLRVCQVSEALLQFEYSRQGLAWSAAGGGPAAAASPMAPAGVADGGSGGAAPATDGFAPHAQLLARAEVLATLGGDGGEAGRAAAVAEASARAAEAARQAADARFAAEVAQYEAVSARSQLEAHVPALVSRSLDLAGAAAEAEPVVRALGQLLGTKLGPALQEVAAVVVQHSAAADVASVAAAVSAHFERCRAAVGVLAAALPSVTAALAAADAVAPLPADMASEVGFLSAQLLGGEAAAAATSARARALLHHLSATAAELQPNAHTILELPRATAHLSSELGTLAAAAASIAAAVQSKHLLPAALPDEAPMAPHTAGPVASVEHKQQQKQEEEEKEEEEEQAGAEDSNGGARGAAAGVGPGSTPLTPLPAAGDGDGVAAARPAVAAAAVALAGGVPDDHVQHHRSRRSAADEARRRAFAAAALRRFAFKLEGREGAASAAAVAGASAAGGGGASGLQASAAAAEGTAAGGGAAAAPVLSVSEQVELLIRQATDPDRLARMYEGWAAWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W8H8</accession>
    <name>A0A835W8H8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 14">Pyruvate kinase</fullName>
            <ecNumber evidence="4 14">2.7.1.40</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HYH02_010599</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13 14">
            <text>pyruvate + ATP = phosphoenolpyruvate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18157"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.40"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>K(+)</name>
            <dbReference type="ChEBI" id="CHEBI:29103"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2 14">Carbohydrate degradation; glycolysis; pyruvate from D-glyceraldehyde 3-phosphate: step 5/5.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 14">Belongs to the pyruvate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.40" evidence="4 14"/>
    <dbReference type="EMBL" id="JAEHOD010000040">
        <property type="protein sequence ID" value="KAG2439721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W8H8"/>
    <dbReference type="OrthoDB" id="108365at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00188"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030955">
        <property type="term" value="F:potassium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004743">
        <property type="term" value="F:pyruvate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.33.10:FF:000004">
        <property type="entry name" value="Pyruvate kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.33.10">
        <property type="entry name" value="PK beta-barrel domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1380.20">
        <property type="entry name" value="Pyruvate kinase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001697">
        <property type="entry name" value="Pyr_Knase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015793">
        <property type="entry name" value="Pyrv_Knase_brl"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015795">
        <property type="entry name" value="Pyrv_Knase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036918">
        <property type="entry name" value="Pyrv_Knase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015806">
        <property type="entry name" value="Pyrv_Knase_insert_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01064">
        <property type="entry name" value="pyruv_kin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11817">
        <property type="entry name" value="PYRUVATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00224">
        <property type="entry name" value="PK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02887">
        <property type="entry name" value="PK_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01050">
        <property type="entry name" value="PYRUVTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52935">
        <property type="entry name" value="PK C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="11 14" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="8 14" id="KW-0418">Kinase</keyword>
    <keyword evidence="10 14" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-0670">Pyruvate</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 14" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate kinase barrel" evidence="15">
        <location>
            <begin position="30"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate kinase C-terminal" evidence="16">
        <location>
            <begin position="400"/>
            <end position="517"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001958"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008663"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012142"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023317"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00048152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000504"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00224"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF02887"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG2439721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="563" mass="60641" checksum="AC6F67213BD8A6D5" modified="2021-09-29" version="1">MATNHVFFEPPKSLLSILEEDKDLSVPALTKLGCTLGPQSRSVEVLESLLRAGMTVARFDFSWGSMEYHQETLDNLRIAMRNTKRLCCTMLDTMGPEIIVLNRPEAPISLNAGQTLTLTCDKSVAASASVLPISYPSLAGTGLAPGSQVFVGQYLFTGSETSSVYLTVQEVRGDEAICTCNNTCVLEGLALTVHMAHMRNEAPILADSDVAAIRQWGAANKIDYVCLSFTRNAADIAVVRGVLDSCGLEQTRVMAKIENLEGLVHAGDIIEAADSVLLSRGNLGICLDAEKMFLAQKKLLRACNLAGKPVMVTRVVDTMTDAPRPTRAEATDVANLVLDGADGILLGSETFRGKYAVSTVKTVCAICKQAELCFDNQSYYRSLMEYFGCYTLHPNLGKREALASSAVRAAAKINAALIIVFTVTGQTARLVAKYKPACPILTVVCPDIKSDGLKWTLLGEVQARQCMLYRGVLPIMADPDFSLPGGAILDYAIAYAKQVGMVRSGDKVVVSQCPRTGYSDVMEEAGVVKLITVDDHVIPGSAMTFNHPLFVIGSMETLNKQAD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WFD8</accession>
    <name>A0A835WFD8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008417</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000026">
        <property type="protein sequence ID" value="KAG2446425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WFD8"/>
    <dbReference type="OrthoDB" id="10376898at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="75"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2446425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="99" mass="10658" checksum="7169C18606DD5042" modified="2021-09-29" version="1">MHLCTARIVKRRGYGVLARLSGEPSALENAHCIVRGYQGPTLSEMLGYAQYALHVVGDAWVAATSPLAVFGPDRWGISLLFYAAVGLLAYNLIIAAPKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WGE1</accession>
    <name>A0A835WGE1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_008253</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WGE1"/>
    <dbReference type="OrthoDB" id="545792at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="281"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="352"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="506"/>
            <end position="546"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="286"/>
            <end position="312"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2446686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1090" mass="110404" checksum="8E7CE32E6DC18098" modified="2021-09-29" version="1">MVVMALTPGVEGRVIRLEERAPSITTLIVDAMKTAAASSTGPVCTGAEPPVPAAAAKEAAALAPARFSGFATECPDDTGRPHHSPFASAGSHDSDTGSQHRDAGDRNTPDATPSGSASSDQHRLQQLLPGVLQALLPSLLPALLPGAVAAAMPSASAAASAAALTAGTSTAASAAAVAIAPAIVEAALPAALASVLPQALSAALSALLKSAGGEELSTAATAHQSQQAISGERQASLDQQGAAEQQLVRMLFGAEAAAEGAAAAPAAAAAASLPVTVPKPSELTVGSPSGSAAAHSHNSGSSSPTERSSTAVAAAAAGNSMFSRRLSETTVTGSGGVAAVAGSAVIAQRAVAQPPHAHHAHAPVAGGCSRSSINSGNHAPHWPGADGESSVEDALSTCSADALVSPAPFGDACCGNSSAPGTGAAVNSSANSFLFSASSQTHMLPAGLSGSNIEGLSEVSGMYSMSGARDDLLSPSGNGPSPAELLMAAAGRVNGGGANAATMALLAQQQQQQQQQQQQAAAAVAAAQQQQQQQQQLQQLQQLQALVAAGAAGSDLGAPASPPLGLAQWRRDTDASADLWGQADADPLSFAAASLALNQQQQQACGLLQQQQQQQMLAQSLAAVAVSNASGRQLRAEDLLALGGNPAAAAAQLAAAAAAGGAMGSSADLSTYMDAALRRMLLVSPQVASELARACGAFSGAQAQLHHLCCVIAEQLLDVAAMAPEVAAALLRALASHRARGAQATDVDPRVMGRILQLLRAGPAGRQLCLVSLEQWVDGLSRIHKRRAYLDTILHNYQLTLKRLVQAMGHQVHAVNMSLPRQLLNDLSPRALLLLTAELAPYPLLQPRRWSEEIIWAISQMHTMGVDMPLAPGTPAAAPAVAGQQPPVTAFQWEMRRALSAAAEDIAASGGAGGSPTGGSSLASLTGQLSSLGLGGAAAAAAGAANANCPNGAVPWAAHAALHRHLLLGLRRIQSRFFSERLRKVHGLYGEAVDSLLRGSLPQDVLVPEREMVVLVLVLLMLECRMRPEEFDAAFARDLQRCLAVSPVEEVAARLRCGLVPDSPLRIDPHKSRALSQLLKLGALGGPSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WGF4</accession>
    <name>A0A835WGF4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446701.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WGF4"/>
    <dbReference type="OrthoDB" id="48903at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050490">
        <property type="entry name" value="Bact_solute-bd_prot1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006059">
        <property type="entry name" value="SBP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43649">
        <property type="entry name" value="ARABINOSE-BINDING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43649:SF12">
        <property type="entry name" value="DIACETYLCHITOBIOSE BINDING PROTEIN DASA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13416">
        <property type="entry name" value="SBP_bac_8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="1">
        <location>
            <begin position="533"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2446701.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="604" mass="64452" checksum="EF8D96B7E0334A2D" modified="2021-09-29" version="1">MSSVATSQQAPPRPLRVVAPKLALLDSLASRADVFSDTTGVPVSFDLLSFGAFSLRRQSLLLDRSPPNVTHGYDVMIVTPTAYGDAAQVPGKLLDISRLVSGDPSLLDILPAFRAATMYSGGVMAIPLVPAPFLLFYRLDIFQRDNLTVPQTWEQFADLAERYHNGPDGLVGNCNIPVGGTCRGESVFLRALLTSYIQTEGPSHGFLWDPETMQTLVTSEAGETALKMFRRLTAVGPTWSHSPECVQNDFNMGRCFMGVGHPSQFKSGSFGAPGLTRARGKMGIAPHPGTTRVLDRTTLKLVPCDRTRCPLAEEVVMEDGASRLLNRPILLQSTMVMLNGLSPLAFQFYAFQLFALLASASVVGTGRGNGLLLEPNELLPMRLSDVSPDQLKYWVAKGYDPGDAERFLAVYRTTAIKEHIMPEVKIRMASNVTSALNTAAALYNSPATNATALPAILGRLEAALNGIVAAEGGQDAFAQQYRRSLNWVPKTGTGGAASVSPAPDSQHGASSAEVTVALAVAIPCVAADTKCLTLVVTDIYESTALWEKLPASVMDAAVSTHHAVIRQALLVHGGVESATEGDSFIISLKAPVAAAAFCLDVQQP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WGG3</accession>
    <name>A0A835WGG3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_008281</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446716.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WGG3"/>
    <dbReference type="OrthoDB" id="546586at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050374">
        <property type="entry name" value="RRT5_SRSF_SR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003">
        <property type="entry name" value="RNA RECOGNITION MOTIF RRM DOMAIN CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23003:SF62">
        <property type="entry name" value="SERINE_ARGININE (SR)-TYPE SHUTTLING MRNA BINDING PROTEIN NPL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="55"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="137"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="42"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="137"/>
            <end position="171"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2446716.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="252" mass="28555" checksum="8B4510C6D33A5B5D" modified="2021-09-29" version="1">MSEQVPSKEDRDRDSQKEYAPSKDYAEKYPPREPRGGGGHTGGRDYPKSNSGRDNKIYVGGLNFSATKDDIYDVFSEAGKVINIQLVVDHETQRSKGYAFVTFADEDAYLYALRKMNGVQVKGRSVVVNKALNPEEKAQFEREKGTQHRDRDDAPQRRPYHSERPHYERPPGPKVKGYRVTVYGLPESYTWRELKDFLRTQTNAQPTYANIERPGVGYYSGVLDWRWYLSCMVNGMLGAPVLGISCVVGAVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WGI4</accession>
    <name>A0A835WGI4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SCP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_007837</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Probably involved in the defense reaction of plants against pathogens.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WGI4"/>
    <dbReference type="OrthoDB" id="337038at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.33.10">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014044">
        <property type="entry name" value="CAP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035940">
        <property type="entry name" value="CAP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001283">
        <property type="entry name" value="CRISP-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002413">
        <property type="entry name" value="V5_allergen-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10334">
        <property type="entry name" value="CYSTEINE-RICH SECRETORY PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00188">
        <property type="entry name" value="CAP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00838">
        <property type="entry name" value="V5ALLERGEN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00837">
        <property type="entry name" value="V5TPXLIKE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00198">
        <property type="entry name" value="SCP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55797">
        <property type="entry name" value="PR-1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0568">Pathogenesis-related protein</keyword>
    <keyword evidence="2" id="KW-0611">Plant defense</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032456715" description="SCP domain-containing protein" evidence="3">
        <location>
            <begin position="26"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="domain" description="SCP" evidence="4">
        <location>
            <begin position="2"/>
            <end position="138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003143"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023265"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00198"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2447087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="150" mass="16388" checksum="15725BDB96AC46FE" modified="2021-09-29" version="1">MYRGWHQAPPLTWSASLAAAAQAYAEVLAPKGCPLIHAGVGGENLYTTTQYPKPDNTCLRAITAWYSEEPYYDYTVANAFQYNWPRGIGHFTAMVWKSGRSFGCGVARADVPMSSMPGGFAGCKIVVCRYSLPVNLADNTAFKQNVLPKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WHG9</accession>
    <name>A0A835WHG9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Fungal lipase-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_007532</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447612.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WHG9"/>
    <dbReference type="OrthoDB" id="544680at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00519">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002921">
        <property type="entry name" value="Fungal_lipase-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051218">
        <property type="entry name" value="Sec_MonoDiacylglyc_Lipase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45856:SF11">
        <property type="entry name" value="FUNGAL LIPASE-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01764">
        <property type="entry name" value="Lipase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Fungal lipase-type" evidence="2">
        <location>
            <begin position="221"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="106"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="349"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="106"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="123"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="356"/>
            <end position="368"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01764"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2447612.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="529" mass="56631" checksum="7C2C8BDB06617747" modified="2021-09-29" version="1">MQTGYWIRNSGCLSSSYCSSNGWCESASTWTTTRGCGSSSTVSTRESASSSCRSNGCGYGGCNSNEIEVSSSWCYWPPSYNERCCTKVITSTCRDWLACSWVQNPNPPPPEPRRSPPPPPPRASSNSGGSSSGGSATAVFSSGGAWDAYASSNKGTNAYIAAILANHAYADSVGASRTNLDDWSTKSWAKVGTPMGAERASYAFGNEGAAWIVYETRDTVFVAMRGTEPSDANDVANDLDVSWANAHSYFGNNAYIMQGWYTVFTANVRFFKQEYDKFITGGARSKKLWFTGHSLGGVMATLFAAYMQRNGYSVQGVYTFGSPIVGDEDWKDAYPLVITKCSAANRRRQMQQVIPSNRSSADSTNSSSSYEAELCGYSTTLERNGTTVTAHTYNCTEPAPAKRTAAPPKNATLPSSSTSSSSNTTSSSGDATDGGLAELGALDALDALDAPTAAPEDSQQPTVNATTADGTTAARAFYITNPLYTFFAVKNTAGGAHYMSDSYMKIIYFCYLSSSERARVPSWSWANRP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WHH5</accession>
    <name>A0A835WHH5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Luc7-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_007409</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Luc7 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WHH5"/>
    <dbReference type="OrthoDB" id="10266921at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005685">
        <property type="term" value="C:U1 snRNP"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006376">
        <property type="term" value="P:mRNA splice site recognition"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004882">
        <property type="entry name" value="Luc7-rel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12375">
        <property type="entry name" value="RNA-BINDING PROTEIN LUC7-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03194">
        <property type="entry name" value="LUC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="234"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="2">
        <location>
            <begin position="94"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="250"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="369"/>
            <end position="379"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005655"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2447482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="379" mass="44277" checksum="94157BEA1FC02393" modified="2021-09-29" version="1">MVDAMRAMLDELMGKERNVPLNQRSNKRIRFDDPTVCKFALAGLCPYGLFKNTRSDLGPCGYEIHDDHIEWETLQGEYNKQDPREHERYERRLMKVMEDLIREMDRKIAKAKDRAEAESSARPLKPEDAARLADMQAKAKEMLQKSQEAGEAGEVDVSMALAQQATEMQAQHDRLHKSLTAPERTMSVCDICGVFINSTDNDQRRQEHLTGKQYLGWKAIREKYAELTSRWEARARSREPELPPPPSLPSRERSGPPPEERERSHDRERERSPRRDERGYDRGRSGGSGHDDRGGYDRDRGYDRDRGYDRDRGYDRDRGYDRDRGYDRRDDRGYDRGRGSYDDRRDRGGYEDRGRGGGYDDGYRSGSGRRSDYEDRRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WHK8</accession>
    <name>A0A835WHK8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007489</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WHK8"/>
    <dbReference type="OrthoDB" id="551189at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="170"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="63"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="238"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="271"/>
            <end position="280"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="282"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2447566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="329" mass="33003" checksum="059C1D2CEFC4C81D" modified="2021-09-29" version="1">MRHSPQYQQQYPQHSQQHQQNQQRQHQQQAPTSGTAPPSFLSSGPLRPLPPSLMLGGGGGGVAAPRPTAGAAEPAVARTASSPWRMSNSGGPALPHTGSAGLGGHGGSSFEGGASAMHGGGRGGTGGGILSKLSYSGSSSSNNNMSFAGAAGGSASSAFGFIAANHGGGGAPPGRTAGEDRGCSNPIARGSYNGGFPSLGPAAAHNAFPTSTGGPMPGELQRWQPAPQQLQQRRSMPGGTGGSGAGTGGVHGQAEHPAAGGAPSQQQLAPAAGVVVAGDGTPQPPQPQPQPQPQQQQQQQQQQQQQQQQQQQQQEQACFQPYPQQQGNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJK9</accession>
    <name>A0A835WJK9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_006209</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000016">
        <property type="protein sequence ID" value="KAG2448858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJK9"/>
    <dbReference type="OrthoDB" id="550170at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="277"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="605"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="625"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="261"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="286"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="340"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="378"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="426"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="527"/>
            <end position="538"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2448858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1146" mass="111740" checksum="8C3504B0040B60BD" modified="2021-09-29" version="1">MEAAAGARLSSRTACCGAVVGGGAGGLDAGQPLQYGIQLNQQVMAAMAQLCVRLQLGAKPRRAASAAVQAPAEGAAGSRQPVAGASVHRTPVAGADAAGAGAAAGAAAGAAGAAGAAAGRASFFHSAGAVPATAVPRGARTSAVAAPAPVCGAGARKRAAESGPGELHAAIELPAKQLKRPHPPHDQAQQVAAEVAAAAAAPALCHMPAASRPLSSSALHSTGAAASCDGSDTPSAPSAPAPPPLRRAGSALTSMLSSQHPGPAGALGAPPGASGPAYGGALLPPSRQPAPPAPAPAAGAVAAAVAVGAVSSGAARLEVHSYHNHTQQLHRTELARQHRGAPPTGRAAAAAAAQVGAARTAAAAAATHGGASAQPVMPEAPPPAQPPPPPQKHQLVCALPAPCLTLQELLTQKSAKQHQHQHHNNPHLSQPSNSNAAPAPAAAAAQPPPPPAATAYPALLDAALRSADPAVVAALQATASAAAQQQQEWRSQLPPLDRLVCSWVLAELPAQLLRQPPSEGVASGRGLVRGGGGAGGGADAPMQPLAAPQSMPGVVGGMGQGVSGTCGGSSAVQGAPLGPCWGGSCASRDEESDGESSGGAHGGVATEPLLQFSCTPFRRRRAAQVLPRRRAVTGEVRQHQGATGQPPRLPQAALAAALEPDACESRGDLWALFCHVMEAQQAEQEAAAAAAPAAAGIEAEAAAPAAAGNEARLSDRYGATEAEEGEQEGAEDDPDVYITDDALACLAALGSEPHGRCGWSIPVIVRRWRCGGGGGGGSMGPGGAAAGAQPDTPVCTPRRDSVGGSVSMDGDDGGAGHGSSCAGEGAGTVCASGRAGGRVSGGSAADAARATLYFGPPLLDQMGLVLGSWSRMCSRAMAAGAAGVAAGCGAGSAEGERSPDCDGGGGCKPPGEGMLAGPHPHHDTCAAADSDSCKCCQQDEWRLGPCGAAASLLVLSHCHVAAAAAGAEAGEEEGKGTGACSGRPGGGAGGGPGCAHEVEPLQVVALAAHGGARAAVRAGGGDMGCSGGDAWGGTSGSSDAVAALAAAAAHYPELAVRAQLLRGGVETQVVVVDPADGALLAEQRLGPGALERLAGPAQVERCWQLAAQLLGWLQRLPPGPYLLRLDLAAQRLELLCGAGREPAELQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJM0</accession>
    <name>A0A835WJM0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">HTH HARE-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_006222</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000016">
        <property type="protein sequence ID" value="KAG2448873.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJM0"/>
    <dbReference type="OrthoDB" id="547517at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007759">
        <property type="entry name" value="Asxl_HARE-HTH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05066">
        <property type="entry name" value="HARE-HTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51913">
        <property type="entry name" value="HTH_HARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0804">Transcription</keyword>
    <feature type="domain" description="HTH HARE-type" evidence="3">
        <location>
            <begin position="35"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="135"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="440"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="623"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="784"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="818"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="135"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="178"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="200"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="220"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="243"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="260"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="282"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="344"/>
            <end position="354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="629"/>
            <end position="643"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2448873.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="841" mass="85170" checksum="02F55A02C5719D4D" modified="2021-09-29" version="1">MSEDRAKRGLRSRPSDRSEDDKAPRASGGAAGGGGIFKSAAVAVLRQHRKLMTTGDITRLAVEMGLLKCQGKTPEATMASALYTDVKRKLQKSLFTRPQEGLFGLREWLDEGYYPEGWVGPPDGLGLAPFKRRNSASAHAGGSGGSSPSKASRTGVRTGPGRSSKARASRSWRNAGSDAEDDDIILDDDDDSPVARPRRGGGISPAGEAAGGSGTALAGLDDEDGDEGLGEGEDLDGEDGMEVDGALEGAAGEVGVAADGSRHESPEPGPTGDRRPSGGGAEQAEPQAQVQAAAGPAGQAAKEEEEEERHGGADAAGGLASARPQPSPSPGPGAGRRGGARSRSGGGGIVGDGGLAQDECLSPLHMLGEAAMSESQGDMPRAGGMSVDQPPSKRKRPTSIAVPERGGGLGGVEGITPKSPYEDSLAALHEIATSPSTFELTSVREQRDATSGLGSGGKGGRARPRLHVDVPGTGDLVGGLNSRRDGTPGASLLTDNLMLHGETTPAILVQASPVTTADGQQAMVYRQAPVMVTLPPALASPSAAGMGQLDSQPLVHVQLPNHIPAELMHMLTPGGHQQLTPGRQPSLTGLGGGAGPRGGVLKVEGPTSSRAPGRRVSFSGQVGILGPPSAGPPMLQPLQPLQPPSLTLPSQPPPSTSGASGGQQVWPPRLTPAQVESELVEIKRVQTVVERLESKLGNTHPQVGKAWLALARMYQHVAEAERNNGVNCASSMTKATEALRRAWAVCRGCAESCGASIGCDEAFEYLTSSCSNAAAAAAASQVDGALPRTGTPPPTGDGAGVLGNEGISPVVEKSAGVTAAGVPSTTGAPEGEGAGAMTVQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WKN4</accession>
    <name>A0A835WKN4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_005794</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="7">Belongs to the DEAD box helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2449043.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WKN4"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd17966">
        <property type="entry name" value="DEADc_DDX5_DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18787">
        <property type="entry name" value="SF2_C_DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000079">
        <property type="entry name" value="probable ATP-dependent RNA helicase DDX17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000629">
        <property type="entry name" value="RNA-helicase_DEAD-box_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014014">
        <property type="entry name" value="RNA_helicase_DEAD_Q_motif"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00039">
        <property type="entry name" value="DEAD_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51195">
        <property type="entry name" value="Q_MOTIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 7" id="KW-0347">Helicase</keyword>
    <keyword evidence="3 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box RNA helicase Q" evidence="11">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="9">
        <location>
            <begin position="139"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="10">
        <location>
            <begin position="342"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="short sequence motif" description="Q motif" evidence="6">
        <location>
            <begin position="108"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="33"/>
            <end position="45"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000492"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51195"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2449043.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="444" mass="49172" checksum="2D24E45973A88DAE" modified="2021-09-29" version="1">MSHYSSHGRGDDRWGGGGSSYGGGGSSSRWDSGGFGGGGGGGFNSRGGRDDLDRMALPRPDFSNLPKFEKCFYLEHPAVSARTSDDVERYRRGKQIHVYGDGVPKPVTTFEEASFPEYVLEEVLRAGFKEPTPIQCQGWPMALLGRDLIGLAETGSGKTLAYLLPAVVHINAQPYLQPGDGPIVLVLAPTRELAVQIQQECQRFGASSRIKNTVVYGGAPKGPQARDLRGGVEIVIATPGRLIDMLDSRITNLRRVTYLVLDEADRMLDMGFEPQIRKIVDQIRPDRQTLLWSATWPKEVQAIARDFLKDPYQVIIGSPELKANHNIRQVVEMVEGYAKYGRLRKLLDGEMDGRRILIFLETKRGCDELVRQLRTDGYPALGLHGDKSQQERDWVLQEFKNGTHPIMLATDVAARGLGNVASRRALEKNTPQHSPAQAPRSRRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WL01</accession>
    <name>A0A835WL01_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">VASt domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_005186</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449654.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WL01"/>
    <dbReference type="OrthoDB" id="541621at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="At1g03370/At5g50170-like"/>
    </dbReference>
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        <property type="entry name" value="VASt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46296">
        <property type="entry name" value="BNAA05G37250D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46296:SF8">
        <property type="entry name" value="OS06G0297800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16016">
        <property type="entry name" value="VASt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51778">
        <property type="entry name" value="VAST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 4" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="549"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="domain" description="VASt" evidence="5">
        <location>
            <begin position="337"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="157"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="222"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="157"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="176"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="240"/>
            <end position="255"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51778"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2449654.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="647" mass="65036" checksum="678C4D62156190D4" modified="2021-09-29" version="1">MRVTPPPPGTHARTHPQIHEQLHDYQLHIKLHGLRGLAALGSGGAAASAGLALQFSLCGWEQREPLRCALSPGGEAAPEDMELVVPLGAAYAEAESLKGRLRDQFGEVRIDLMSWKNKLARTQVPIWDVPFKAEPIPAPVVSEAARAAVATSVPGSLIGGVSSSGPSGPSGPSGPRPAAASSTAEPPATPVNGAAAASDATKSFLGVFACNMANAMAAVGGGGGGGGSGTQANKDAPSAPASPEPPAPPPEPPAPLWAGKRYVRKLEKLDKVLDKAVAGQAPQKPEVEVSMQLVRVADANASKADGGGAGGAAVGAFDWDAVDVETPAEPLAAPPPHPHSACDYVVKAGPHELLRSLYGPNAVCADKTQALEQMTDYKKGEWGPDPDGKALTQRTVTYMKPTPVGPTPVTSVQRVLTRTDGGWVVENRVTPNVPPVGQCVHVFMQLVGQHAGPGKTRLTATLRTEWFKSGMMVNVVKGKVEAATPPDAVKFFNTLKAELAAKYGVEGGGGVGAAGAEGGAPEAGAAASPVAVAAGGGSAGTAFGGASPVLLLALVAGLGLVLLLMVLVLLRVVSELGHSARAFEALAGALEALPGRLAAVQQQALAAAAAAAGPQHSCPSTAVAAEVAAPLVTAAVEAAAAAISGSQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WL15</accession>
    <name>A0A835WL15_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_005531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WL15"/>
    <dbReference type="OrthoDB" id="10279460at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2449381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="87" mass="9664" checksum="AF97738CA7A62FAB" modified="2021-09-29" version="1">MSLCSKSADEVAKHVVTLLAACEDAFDEEWEKVWQYLGEDYRCVGEGYEEVKALLNDEHKALLQKVHEMGQAEGHAARRAGLAGLKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WL25</accession>
    <name>A0A835WL25_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_005970</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2449224.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10625398at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1209"/>
            <end position="1234"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1780"/>
            <end position="2414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="600"/>
            <end position="630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="765"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <begin position="923"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="969"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1085"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1172"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1258"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1353"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1620"/>
            <end position="1687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2052"/>
            <end position="2129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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            <end position="2365"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2420"/>
            <end position="2448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="600"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="945"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="979"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="997"/>
            <end position="1006"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1089"/>
            <end position="1103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1182"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1391"/>
            <end position="1412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1638"/>
            <end position="1652"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1672"/>
            <end position="1681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="2091"/>
            <end position="2101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="2153"/>
            <end position="2167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2168"/>
            <end position="2189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2339"/>
            <end position="2348"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1807"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2449224.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2448" mass="245874" checksum="5F1178BAFE62FD8E" modified="2021-09-29" version="1">MFASKQASTEPGPPETILDLRAFVDGGPAFVVQAGARLELHNLTLLLPPLPLGVTATGPGITLLDQLFQAAGLFGDANTTTTTSAAAATNSSGSSRPGEAEVLLQGVTLVLDSEWDLRDFTHRLCVAEEWTYTTELQVMDGVVRYTSAAMAIGTAAAAAPPSTAGGDTTIPLDLPALGSPAPTAPTARLANVSVTCCLAGDNSAGGGGSNSGGGPPQGSWLCGATHVSDGRQLLAAARRLLGSSEEVVHISLAADVQVDPADWVRPPPRAAGTIFETSYTYRAAVGDGVVGVGAAQRLILYGPPPHAVSGGGGNGVGGGSNKLTRLLVPSRVLDWSGVEAALYTATGAITFRDLHLRGLPYPDTVLQPRDLLAGWVHAVRPERTTILPVGIIGKRTTASIRLERCSVLLPDREVAWWRAAAAAGPGSGMLDDPGGSGMRYAGGIDTARITLSPPEQQQLVLQQLGLAAAATADSGAPPPPGGGGDGAVATAQVLPLLVSDMTEERLMHSTSLRDCVLLPMSVAAAATAAATVAGARTSGSSTDTSSDAAGGVWPIAEGYTEEESAQLRIGLMEMPFGPVPDSILGALCAWYSVGYAPPPPPPPSPAPPRPPPGAPLSFSPASQQQPTEQASAAAFALLGRHPRLLLPRLLARSRTSLLPTAWSHGLPYVDPATARAGWQEKAVMVNPSQYGWMFTLSGMPIGDEGGGGDRLRVCNVAGAPASQTGRVTYWDMRSASGRARLLPGLVFMLERIVLYNLSPAGPDRLYPPPPPTAPGPPPAPPKPPRFPAPPPSPPGAPPSLPPSPDPPSPPDHPTAPPLPPEWPAASAGPYYPFPPSPPPPWVAPSVSQDSVLRRMALPLWNFILDRTPEAMAQFDSAAGSLLLLRNVTLVVPAWELQLLRRLLQEAGRLPTVAASVAAAAAASGSSAPPPQPAAASQLSPPPLAEGGGAGSGGPLLGRRLRLVTQSDGISKSLSRRRVQQQQQQQDRQQPASPPPAAVSAASGSTSGSASACATRSLLLSYAAASEVGWATDTSLFLTVAAHHGWRGLDVTLTSTLPEDAPTQPMVTSSPATDPNLAAWLAELQSPTDCSPPPAAQPQPPAAPPAAAAPVAPPPPQQPPAAGGAGAAIAAAPAPPPTAVERRAPPPPTAVAVAPEPGGTAVGASSAVGPLADADGAGGASTGVGVSSSSSSSSSSSSAAARSPSAGQRLALAIGLALPLGAVLVVLVAMAAALWRRRGWSYSGAASAAKQAALQGGDDAATAGMGRADGDGSKFVPGSPTSAGQVSSFMGTTPLGAAAAARAAAAAAAAAGPAGAAAGAAAGAAAAQSGQPASISAQPKGPLLTALRRALSSLTGDGRRRLRHAGSSSGTAGDTPRASRYTQPGSAGGAAGVSSSSPTVDAAGSSLQNSNSGGNCGGANTAVEAVAAAAAGPMSVSVLGASRTATTTTAAAATAAAVAAAAAAGPPDMGEVDAFVRRYLEDCDRRMAAAASDILSSAAAAAQSAAGTAATAATAATATAAAALVGEVKPAAGGMVNVDEASWLAELVEEPPDDFGVAMGSAQQAADAAEDAATGFTVRLPGLPYLQLGKSTVESMDLLRTPSGSHVYGHRLLARRLLRDAADSGGEQAPSSNSGGAGCRQQQQQQAAGAEGADPSSASLAFPSTPRLRWRSPPQARALPRATPLPPTVTPRMAAALLGVSAAARQPAVAGGGGGVAVVRGGAQALGSRGGGTAARNGLVLGAAANSTSTSSLNDVLRDWFTKGPHQALAVHQHQRGGNEVALIKMIGRGSFGTVHLGWWRGLPVAAKTLVVHDTLFGREGQRRHRAILEAAIGSSLVHTNLVATYAFDVQQMSERPTVEQQLQRLAAGGGLAPNCDVYKLVIIQEFCGGGALKEALRRAASMAAVNPDGGNPLSALHGGAQAAAAALHIALDVACGLRRLHAASIVHGDISAGNVLLAAAPPPEEDEVAELLLMKMMATGASAETEATAAGAAGVVDTEINRCTGAAVAAVTRSASAADREEFVIAASSTGTAWRQPRVPLEGVATVTGSSADVTTGVPAGGAVQEPHVQPGKIGPEAPPPPPPGSSSSPHLKHLHPHPQQHYRQAEQQVPHHDAGEAPAAAVDGSGGSPLRALGIDELEAGCRRRLLMLMLMPPPEQPPAPRPAAPPAAAAGMQQQQQHQHQQQQQPAPLYRPTILAKVSDFGLSHRLEAGRTHASGKYQGTPLYIAPEVMTAGRLGKAADVYSYGVLLLELLHGKEAAQMWDEYAARAAGGKGGAAAAAGQPPAPSEVWGAQVAYLEQLLSRATAGAGSAVGSSGSGSGSGDGGGLCIGLPLPPAVTPAGGPEEGAAGIGMQPPRTPPLSPSPHMSPVSFLGLEIVAALHALVRRCLSLAARDRPTFDQVLLELTACLEKLLTRMRSDWSSSSSSSSSGGGGGGGSKPPTAGDTVH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WL29</accession>
    <name>A0A835WL29_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">shikimate kinase</fullName>
            <ecNumber evidence="4">2.7.1.71</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_006123</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Catalyzes the specific phosphorylation of the 3-hydroxyl group of shikimic acid using ATP as a cosubstrate.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>shikimate + ATP = 3-phosphoshikimate + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13121"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:36208"/>
            <dbReference type="ChEBI" id="CHEBI:145989"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.1.71"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Metabolic intermediate biosynthesis; chorismate biosynthesis; chorismate from D-erythrose 4-phosphate and phosphoenolpyruvate: step 5/7.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the shikimate kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.71" evidence="4"/>
    <dbReference type="EMBL" id="JAEHOD010000016">
        <property type="protein sequence ID" value="KAG2448770.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WL29"/>
    <dbReference type="OrthoDB" id="197068at2759"/>
    <dbReference type="UniPathway" id="UPA00053">
        <property type="reaction ID" value="UER00088"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004765">
        <property type="term" value="F:shikimate kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008652">
        <property type="term" value="P:amino acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009073">
        <property type="term" value="P:aromatic amino acid family biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009423">
        <property type="term" value="P:chorismate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00464">
        <property type="entry name" value="SK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00109">
        <property type="entry name" value="Shikimate_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031322">
        <property type="entry name" value="Shikimate/glucono_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000623">
        <property type="entry name" value="Shikimate_kinase/TSH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023000">
        <property type="entry name" value="Shikimate_kinase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21087">
        <property type="entry name" value="SHIKIMATE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21087:SF16">
        <property type="entry name" value="SHIKIMATE KINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01202">
        <property type="entry name" value="SKI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01100">
        <property type="entry name" value="SHIKIMTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01128">
        <property type="entry name" value="SHIKIMATE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="10" id="KW-0057">Aromatic amino acid biosynthesis</keyword>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002641"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006997"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012154"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00048567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2448770.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="336" mass="36396" checksum="8CA091D4C9C56BFA" modified="2021-09-29" version="1">MSVSMIQRPGAGVALAGPVQRSSAALRPLASPVPFTAHRANVSGKRILRQGARAEPSRVVVVRAEKATEDGGVTPGHPYPWEEDFDLLGDKVKEVTDQLLPDLRGCNIWLVGMMGSGKSTVGKMLANTLKYAFFDTDSVIELAHDKKPVSQIFAEEGQDYFRQCESQIIKELSPYRNLVIATGGGAVLKPQNWGYMHLGIVAWLNGDTELLARRVSKDGIEKRPLLAADAPEGADVQAVAKAKLDTLLEDRRKYYENADVVVTLEGYGKDLEGGAPTAAVMYRLLLAINDKVQAKKREQADRMNFTIEGADQLKTMRAVDSPAGGLQLDGSGPQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WM23</accession>
    <name>A0A835WM23_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">NAD(P)H dehydrogenase (quinone)</fullName>
            <ecNumber evidence="2">1.6.5.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_005621</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a quinone + NADH + H(+) = a quinol + NAD(+)</text>
            <dbReference type="Rhea" id="RHEA:46160"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.2"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a quinone + NADPH + H(+) = a quinol + NADP(+)</text>
            <dbReference type="Rhea" id="RHEA:46164"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:24646"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:132124"/>
            <dbReference type="EC" id="1.6.5.2"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the WrbA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.6.5.2" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449476.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WM23"/>
    <dbReference type="OrthoDB" id="504689at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003955">
        <property type="term" value="F:NAD(P)H dehydrogenase (quinone) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.360:FF:000001">
        <property type="entry name" value="NAD(P)H dehydrogenase (Quinone) FQR1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010089">
        <property type="entry name" value="Flavoprotein_WrbA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005025">
        <property type="entry name" value="FMN_Rdtase-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01755">
        <property type="entry name" value="flav_wrbA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF002999">
        <property type="entry name" value="PRK03767.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546">
        <property type="entry name" value="FLAVODOXIN-RELATED PROTEIN WRBA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30546:SF23">
        <property type="entry name" value="FLAVOPROTEIN-LIKE PROTEIN YCP4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03358">
        <property type="entry name" value="FMN_red"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="6">
        <location>
            <begin position="72"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="33"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047678"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048983"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2449476.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="270" mass="27753" checksum="7A925FDCED020F24" modified="2021-09-29" version="1">MGNVCGGASGQAVDQHGKPLTKTPAAETKTEAAKPPAAAPADAVPPAAASPAAAPAVAAPADAAAGKKKLKVYIIFYSTYGHIEKLAREYKTALESVGDVEAHLFRVAETLPAEALEKMHAPPKPDDIPVMETGKLPDADAFVFGFPTRFGMMAGQMKNFFDTTGQLWQAGALHGKPASMFTSTATQGGGQETTIMTAVTQLAHHGMIFVPTGYAAGAAMFGIQDAKGGSPWGAGTLAGPDGSRQPSEVELEALRVQAKHFGGIAKKLAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WM25</accession>
    <name>A0A835WM25_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">AMP-dependent synthetase/ligase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005232</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449704.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WM25"/>
    <dbReference type="OrthoDB" id="10253115at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.300.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12780">
        <property type="entry name" value="N-terminal domain of ligase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045851">
        <property type="entry name" value="AMP-bd_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020845">
        <property type="entry name" value="AMP-binding_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000873">
        <property type="entry name" value="AMP-dep_synth/lig_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042099">
        <property type="entry name" value="ANL_N_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44378">
        <property type="entry name" value="ACYL-ACTIVATING ENZYME 17, PEROXISOMAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44378:SF2">
        <property type="entry name" value="ACYL-ACTIVATING ENZYME 17, PEROXISOMAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00501">
        <property type="entry name" value="AMP-binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56801">
        <property type="entry name" value="Acetyl-CoA synthetase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00455">
        <property type="entry name" value="AMP_BINDING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AMP-dependent synthetase/ligase" evidence="1">
        <location>
            <begin position="219"/>
            <end position="582"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00501"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449704.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="853" mass="89134" checksum="63B9A22AC9FE38B3" modified="2021-09-29" version="1">MSKYHESVREALASSGVASPQQVGELEMLLRGLTGECAADAPKIWSHLARNVLLPSHDFASHLELADAVYGQWPAAALGRPPLWLPQPPDACRTNIATFLERIRDEPWWRDVTGGCGGVASGSCCRTPEALVRDWRLLQRVSWEAPEAFWPAVLRHLRIRFHTPPCRALLRHPSDPDQCRWLPGARLNIAAAALESELAPPGCPALLWAPDGEPCAITAFSRAQLRQRVAAVAASLRRCFKPGDALALYLPLTPDSVALYLAAVAAGCVVVSVADSFSAEELRTRLDIAKAVGVFTQDVVLRGGKALPLYDKVVRSGTAAACVVLPAAESAGAALSAAAPALRAGDVTWRAFLGAATAEAELVELQPHIADVYEVTNILFSSGTTGEPKAIPWTHLTPLRCALDGWAQLDVRPGAVVCWPTSLGWMMGPWLLYAALLNGGTVALYGGAPLGRDFLQFVSAARVEVLGLVPSIVRAWRHGGAFEPPKPPAAAAAEAAGAAPPLPLPPPLPDLSAIRVFGSTGEASAAEDYHWLMSRIRGYRPVIEYCGGTEIGGGYISSTLLHPCAPSTFSTPTLGTRLVLLTSAESAAAGEDALGRSGQAVCDGGPSWWNGGSARRFLSTSSSTCSSACPPSSGAAPAAAGMAASGGVLLTGEVALAMPMLGVSQRLLNKDHHKVYYQGMPLYGSTGLPLRRHGDEMAALPAPAAGATCSGGGPPAWCYAALGRCDDTMNLGGIKVSSVELERAVVEGVVGVAEAAAIGVAPPHGGPEELYLFLVLRSSGDSASAGSSSGSGSSSVDVAALHKACQEAVRGKLNPLFKVTRVAVAPLLPRNASNKVMRRVLRDQLLQAGRSKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WM50</accession>
    <name>A0A835WM50_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 8">folate gamma-glutamyl hydrolase</fullName>
            <ecNumber evidence="3 8">3.4.19.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_004819</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>(6S)-5,6,7,8-tetrahydrofolyl-(gamma-L-Glu)(n) + (n-1) H2O = (6S)-5,6,7,8-tetrahydrofolate + (n-1) L-glutamate</text>
            <dbReference type="Rhea" id="RHEA:56784"/>
            <dbReference type="Rhea" id="RHEA-COMP:14738"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:57453"/>
            <dbReference type="ChEBI" id="CHEBI:141005"/>
            <dbReference type="EC" id="3.4.19.9"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Secreted</location>
            <location evidence="1">Extracellular space</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peptidase C26 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.19.9" evidence="3 8"/>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450313.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WM50"/>
    <dbReference type="OrthoDB" id="64220at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005773">
        <property type="term" value="C:vacuole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034722">
        <property type="term" value="F:gamma-glutamyl-peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046900">
        <property type="term" value="P:tetrahydrofolylpolyglutamate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.880:FF:000054">
        <property type="entry name" value="Folate gamma-glutamyl hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.880">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029062">
        <property type="entry name" value="Class_I_gatase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015527">
        <property type="entry name" value="Pept_C26_g-glut_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011697">
        <property type="entry name" value="Peptidase_C26"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11315:SF0">
        <property type="entry name" value="FOLATE GAMMA-GLUTAMYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11315">
        <property type="entry name" value="PROTEASE FAMILY C26 GAMMA-GLUTAMYL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07722">
        <property type="entry name" value="Peptidase_C26"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52317">
        <property type="entry name" value="Class I glutamine amidotransferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51273">
        <property type="entry name" value="GATASE_TYPE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51275">
        <property type="entry name" value="PEPTIDASE_C26_GGH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0964">Secreted</keyword>
    <keyword evidence="5 10" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032670895" description="folate gamma-glutamyl hydrolase" evidence="10">
        <location>
            <begin position="21"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="334"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="341"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="7 8">
        <location>
            <position position="144"/>
        </location>
    </feature>
    <feature type="active site" evidence="8">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="7">
        <location>
            <position position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011083"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR615527-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2450313.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="397" mass="44283" checksum="C6C40351780E7D3C" modified="2021-09-29" version="1">MARTAALLALIVAALALAQGARLGVQKEITSGVSDSYVPTKYKNTKPLIGVLTQPCHDCPGKSYIAAGYVKWIEMGGGRAVPVRFYSSDSELRRLFNSLNGLVFPGGLTWLWLDSPYVIAARKLFNWALEANNKGDVFPIHGTCLGFQLLHILASNISRNDLLVDTDSVAHPSTLIWTPEAAGSRLFGGLAPDLHDKLADPKFNIALQNHMYGIPPSFYQKFPVLAKWYKPLSTTLDRNGTEYISTMEGIKYPFFGTQWHPEKPPYEFGMEEVPHSLDAIRVSQHLANVFLEAARMSSHKPESKEEELAMEIYDTAPIFSARFEVMDEENYDGPDITYYFDQKDKPPHGPDDDEGEDSGPTRAERAPGSAEQEGEQLSEQEERALHFKFWSTQGGFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WMS1</accession>
    <name>A0A835WMS1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_000326</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000012">
        <property type="protein sequence ID" value="KAG2450227.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WMS1"/>
    <dbReference type="OrthoDB" id="545609at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2450227.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="157" mass="16639" checksum="B428B377697183B0" modified="2021-09-29" version="1">MPPLPPVDTGRLQEPPEGHWRPVALAMRATSAQVAACRAALALYRERMEVVMAERGRLTERLADSMAALGLEQEAEGGGRGRLLSTQQLERTSVEAAAAAAELDANVAAEGRATKIAKDLLSSDMFTALQCARGSMASYPYFPDALAIITEVAKLGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WMS4</accession>
    <name>A0A835WMS4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_004875</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SEC15 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450370.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WMS4"/>
    <dbReference type="OrthoDB" id="10267033at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000145">
        <property type="term" value="C:exocyst"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006893">
        <property type="term" value="P:Golgi to plasma membrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090522">
        <property type="term" value="P:vesicle tethering involved in exocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.670">
        <property type="entry name" value="Dsl1p vesicle tethering complex, Tip20p subunit, domain D"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.357.30">
        <property type="entry name" value="Exocyst complex subunit Sec15 C-terminal domain, N-terminal subdomain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007225">
        <property type="entry name" value="EXOC6/Sec15"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046361">
        <property type="entry name" value="EXOC6/Sec15_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042045">
        <property type="entry name" value="EXOC6/Sec15_C_dom1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048359">
        <property type="entry name" value="EXOC6_Sec15_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042044">
        <property type="entry name" value="EXOC6PINT-1/Sec15/Tip20_C_dom2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702:SF0">
        <property type="entry name" value="EXOCYST COMPLEX COMPONENT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12702">
        <property type="entry name" value="SEC15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF20651">
        <property type="entry name" value="EXOC6_Sec15_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04091">
        <property type="entry name" value="Sec15_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0268">Exocytosis</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Exocyst complex component EXOC6/Sec15 N-terminal" evidence="7">
        <location>
            <begin position="121"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="domain" description="Exocyst complex subunit EXOC6/Sec15 C-terminal" evidence="6">
        <location>
            <begin position="940"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="60"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="489"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="830"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="10"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="86"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="835"/>
            <end position="855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007944"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022483"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF04091"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF20651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2450370.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1162" mass="116967" checksum="56273268EE133D94" modified="2021-09-29" version="1">MKSAFKDAGAKAAAPAGQPGAQGAPPAAARSEEASIRELVESCLVNDDFTPVLRIVFSGPSKDPATPTAADALLGGGPGASPPPDSASASAAAADPTLQPASKQQPLLDGRPALELLKGVLRSVAAEQDGVVKEVCSLHAMEIATCVAELDRMALSAEALRKAAEASSEALQRAGSTLASTSRDLHGLLSAQRHLAAGVGGLRAVRRLLARCGQVGQLLAARRLFAAHELLEAVRAQDLVLALEVLSNNTAVAAALATGPDAASALAAATAAAAVGSALDVGAGGTAGIAPKHQALVSRLRRFLQGLVSDLEAAVEYYAVAEFNNWLVGVRAESRQVGLRAIRQAAIGRQLGEDLAAERRSVAAALMLAEKGISGPSGAATAAGGAAVAAGATAGSGAAAAGGGGGGGGSSAFAGAGAAAAVAAAAAAGAGVGGGGLDAARGDLVAAVSERVVVGAPFRRDLAAEGAPAPPPGTAAAVPRGLARNATMRASTGSAAGGGAASGAASATSGPGPPIDIGSLHPGQPLQAIQALLARHRAAAASAPPPAVCALTDYTTGLLQGVDMQGLHRCVHIHRRLGRMPSLRRYYLQQRRLQITTDLAPPARFLEAYQAYLAQVVGFFVVEDAVAAAAPDLVSADSAALLWEAAAASLRGVLGRALEEALGGGAPASIMLLLKDFMLLVCSALGARGFVTAPVTELLSASRLRYHDLLTAGVALRVGRALAADPLAEGVRVASEAQAAELVGRLGLPAVLEGYGAGARPAVPYTAPYTACLPRILTAIRGFVSDSLAYLQGLLSPWELLPAVLHARDRLIGKTVVDALADHTARLLGADAAHAPPPPPPSRGAPPPPPPPGPWRPREVMHMVANASCLASAMQALDEWTLLQVRPLGAMAAAAAAAATGGAAGNPLSANRGAAGGGGGGPGGGGGAGTSDPSMGAVLAALRSVQDAGEKGLLRLIAARVEALVAAGGRAANWLPGGPLPMGMSPYAEELLALLRDSFDAAAATLPRSSFLFLARAVARAMGGAFMQLLKEGVKAYNLFALEHLAGDVAALDRYLYGLSLSGAVPGLADEFAEPRQLCALLLSPRVEEVLIPEVRRQRYGALDLPVLVLVMERYREQSRVDRTKEKTGHVPKRVLEGIAKQLRGQMVAGTAMSGPRVLEDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WMT5</accession>
    <name>A0A835WMT5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_005691</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449550.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WMT5"/>
    <dbReference type="OrthoDB" id="191196at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061927">
        <property type="term" value="C:TOC-TIC supercomplex I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045037">
        <property type="term" value="P:protein import into chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031610">
        <property type="entry name" value="TIC110"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34935">
        <property type="entry name" value="PROTEIN TIC110, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34935:SF3">
        <property type="entry name" value="PROTEIN TIC110, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16940">
        <property type="entry name" value="Tic110"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="312"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="218"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2449550.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="682" mass="75492" checksum="5D9DCEC19DA299DE" modified="2021-09-29" version="1">MAALVGEVDALLEYERKLVRYGSEDDLVSGLGLVTIHGGALDVEGKGRDMKDVFRMYLEEKLNGAGEFSAELDADAAELATVMCLGAKETQGLRDEVSAKLYRRLLKEEVTSGRLDAAASPASVLQQLCEKVRFRPEAALELHRQLYKAKLAALLEARRGRGGLTDADAEDLKRIRRILCLPADVAKKVQMETAGKDFEELIGEIYLAGAKPLGAYEADRVEKALKELRLENEVAVDVMARITRERFRGYITQAQKEGNRDRKEFASAIKKLLQFNALMVTPLLDKVKGVDAAKKELAEMLMKAAEEAKKEEAAEAAAASGEKPAEAKPEQPKEDAVEQVRKSIQATRGEFTEEERKAQKEISLKDDLEPAMRGEIYKNYLMYSMSGDVVELPVGGVIRKKSNAQARQAEMQRLTSLADVLGMTQQEVMSAQADLAEQAYKAQASEVMRSGPLNEEKIQYLDEMRTQLGITKETGDKVLKAARLEVYGTSSAAEDGKWSIDRVLELHKTGGSVDTLLEEVTRRNLFRKEVIKKVTDGSGEADVAYFKELLPAALQLPENKIRLIVKEEVSTRKRMLLVQAVSQFRQRRVNEAVTSLQNLLSCLALMPEDKAMAWKERNELQEVFGLFCAKEESEPKRLALRHALGLTEEEASEIAVTASVDAAAGGPKKTGGIVDDSDEDFF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WN47</accession>
    <name>A0A835WN47_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_004784</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450273.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WN47"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="294"/>
            <end position="305"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2450273.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="371" mass="39028" checksum="2613CFA25875D4F0" modified="2021-09-29" version="1">MSQDAGLPSALACYIKRAKERDAAAAAAVGAAAPQGNTEALAILSQEERRVGLRRALRDFGLAEVELAFFSNAYLDFLLQHLITDLPSLRREADPLLLQDAGLPSALACIIKRAKERDAAAAAAVGAAAPQGNTEALAILSQEERRAGLRRALRDFGLAEVELAFFSNAYLDFLLQHLITDLPSLRREADPLLLQDAGLPSALACIIKRAKERDAAAAAAVGAAAPQGNTEAVPAAAGPPPGSSDTGARDQLPPRGGGAVAAAPKSSSWWSAACWLLPTAAAAGSSCRSAPSPLTEPQPQQPEPYYPTAVRPAEHAPDACAPAAHVLEARWGMKDLSTASTQQQQQQQQELLLPATCRRRRAHHADPGQHE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WN70</accession>
    <name>A0A835WN70_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">FAD-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_005271</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WN70"/>
    <dbReference type="OrthoDB" id="531840at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46496">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46496:SF1">
        <property type="entry name" value="ZEAXANTHIN EPOXIDASE, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0274">FAD</keyword>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2449745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="368" mass="39048" checksum="9EF7BB4763D959C2" modified="2021-09-29" version="1">MAKWLVGADGGYSRVRRTVGDGRAPTFLGTFSWWGSATEAQLAAAGADWPLPLRGPRQPITRNATYMPPGNRLSTTGARNLLTFRTPPCEGPGAVDGDEGAGRDVALWYMESQSAAMAAEGVDPSPEGPILRHAAADGGAVALARALRMASHLPPDVRAFIAATPPQRVLEKALHSHPLDQQEHSSWTNGRGLVLVGDAVHASGRPDGQGGNLAFEDAACLAAHVRRHGLGQQAFDAFAAARRPRVTAIRGDCKPPFAVRKALVDGSMFEPLWGPQDLPSKAELEGELLPELGASQNAEEAGHGHSSAGTISEELKRKVLAWSLRRCWAIADRRTGGLMLAVPAAEQVVETEQKVQPEKQAMTASVRA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WNU2</accession>
    <name>A0A835WNU2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">Fucolectin tachylectin-4 pentraxin-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_004713</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fucolectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000010">
        <property type="protein sequence ID" value="KAG2450881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="547680at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042806">
        <property type="term" value="F:fucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010185">
        <property type="term" value="P:regulation of cellular defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001868">
        <property type="term" value="P:regulation of complement activation, lectin pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051941">
        <property type="entry name" value="BG_Antigen-Binding_Lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006585">
        <property type="entry name" value="FTP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45713:SF15">
        <property type="entry name" value="F5_8 TYPE C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45713">
        <property type="entry name" value="FTP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00607">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0106">Calcium</keyword>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0430">Lectin</keyword>
    <keyword evidence="9" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="10" id="KW-0732">Signal</keyword>
    <keyword evidence="9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032289728" description="Fucolectin tachylectin-4 pentraxin-1 domain-containing protein" evidence="10">
        <location>
            <begin position="24"/>
            <end position="3429"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1941"/>
            <end position="1964"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1970"/>
            <end position="1994"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="3285"/>
            <end position="3304"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="3310"/>
            <end position="3330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="3342"/>
            <end position="3371"/>
        </location>
    </feature>
    <feature type="domain" description="Fucolectin tachylectin-4 pentraxin-1" evidence="11">
        <location>
            <begin position="538"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="299"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1154"/>
            <end position="1181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1627"/>
            <end position="1705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2098"/>
            <end position="2121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2380"/>
            <end position="2408"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2516"/>
            <end position="2535"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2693"/>
            <end position="2746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2785"/>
            <end position="2838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="2856"/>
            <end position="2998"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3101"/>
            <end position="3122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3137"/>
            <end position="3170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="3403"/>
            <end position="3429"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="309"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1161"/>
            <end position="1174"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="1627"/>
            <end position="1701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="2711"/>
            <end position="2720"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="2796"/>
            <end position="2813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="2814"/>
            <end position="2838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="2861"/>
            <end position="2874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="2937"/>
            <end position="2948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="2949"/>
            <end position="2958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="3101"/>
            <end position="3116"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00002219"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010147"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011233"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022734"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00607"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2450881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="3429" mass="346582" checksum="6743EEC7CCEABE47" modified="2021-09-29" version="1">MARPTGAIAWLLIFALVVIKADGSHGGRNVRYRRRNLLQGQQEAGPQARVLVYADSLKFSVSGTSQALESLPDVRVTYDTAPTNTPAQFSRQFYDAIVIPKLRADEVDPLVDDYFSLIDFVYDGGAIILGPGTLQLNMTSAFLNNLATKDSSRGDLGYSTALVCNSSAGLGLPNPSSSAMYPLRPGWDPAAAGLAFASPVAWPRFLAAAGGGVQPSAYLIDCGDLRAVNGTAMYGDTMSAPPLPATEAVVLSFPRGDLGGRVYYVGLDLDTAPWTAEWGQLLRAIIMKATSGPLPSNISVASPPPSVPAAPADWQATAPAADPATSSASRPWPLARGRYSYTPGGTTATAAVTKALTAMDGRAEHLCHIVPRPTVNAAGYADPTSSWLVFDLGTARRVYSVRIQALIARMSNEALINATSVDPVRIKVRVGNRPVFSATPGAFGQSSNVADNPELCPPAAAGNSSAGAAYYYLPVGRKPTAYNDPGALVVACGNSGSLVGRYVSISLLDDVAIPSAMSTVKLCGVDVMGAIPDAWQLVSRSKPVCASKNKGGTVYPAESQPSLVVDGLYNNNRNSVMSMCALTDLSTAPYIMVDLGADMVIERVEVTKSASQAHSHQLSDFSITVTSENPCTSPVSVAASPQPFQFCAQGLRLPPGETGVYNCSGMVGRYVSVALPENFTLPRYLRVCELDVYASLPAANGTLAGGWGRESFLLSVNKVTSAAPGSSVDSLLKGQSSSTLRAMAGLLVDGITPRDLRASAAASGSDPAAVPLESMCVNVTLEAVFNTSAWVGVDLGAMFMVRHVTVHYMYDFDELYKLGIGYYSNVRADVTLRLSSEKVAGSRILMEAQPSCVQSAGFFTGLEQTTDLYGTGGSHVRTYVCGFEGRFAYLVAERPSGDFSNPVFLPPFCELEVWVASDASTPVGYLSSLNRVAAFSTGASVGSIATRTGASSGSRALQGPNYVFSALETEKCSKGLGVPGQPASAFWLVDLGSVRVLSMVQILGGLQLTSVRLARMDADVPLDTTAPLSTRTAITLPGAESLLSWQGNGTVTWKPTAGVNISARYVLVMALVAEQPITMCQVWVYTTQEGVPGTRARPGVAVELARGRATQQLGSAPLDITVALRRRQLLALQQQPTLGGRRGMIGVSTASAMESYDSDDSSSSSSSSSSSSSSGSGGARRLLQSGTGPALLFLDLGLVRPVEVAVMTTPSMITYQEISNVQVAVSNVSNATTGGTFCAFDVTLPLSLTRHVFGCGGAYGRYLVATRSDGFALLPDSGLEAFLVDPGNELNVALNRPTNQSGAVVSGAGGSNNAVNGYYDQVSVNTAVLGGRTVAFGSATATVAAPWWSVDLGSAMPLSWVEVTAHPAPADGQGLQSFDIVLSNFTIATGSEGVTVLTGLSLAAGATGRYPLGGAAARQLIVRQPTATRSMQLAQVVVIVDKATVTATDNQLIKPKPLLYPTVRDTNRFTGSYIDSSGVVSSGELSPLAVDGIAASDTVLRCSRTDVSATPSELPWILVDLGASRQVRRLALLKAADPAISAQLDNVDVFLGDAPSGSVTSSNPVVLPGLRLPTPGVWASFAVPTTAAPGRYLGVRGKTAGGTLVLCEMSAYGSSVYELELSPPAPFPPPSPMPPSPAPPSPEPSPPLPPSPPPAPPSPEPSPPEVPAPPLPAPPFLPPLPVGAPTTPAPPSPPSQPPDAPPTSTKQFTLAAALVTTDPTAVTITTASVVAVTVATSLAATLAASAVASAAASGAGGAMVASVPGGAVTGGTGGAAATAFVGHLQFFAVTSHASAQISGSYTDTNSALGWLNLEYDTLLKMGVTWLPDVEQKAYSQALNVGLVFTAVLLVHIGLVLAVQHVRRNAAACAAFWSCRWCAGRQAPPPPPAPASPGGGATTAAGPIAEALESRASIAATSPSEHKKRKLGVTLPDMLVFPYLEIFIYIFFLVSLANAAGMLVAAGFAASPHRVAPIAVGVGILVLLAAITVAAVLLLTRLYRAAARLGLEYVPKPRAPPAGEREGRVSRWLRLAERGFWERPEGVEVKRMEPLRTEHYLTAGPFNPAAALAAANPDARLTHLSRLAARFVRMASTLPFLNSSRRDRTDDQADDQASLGMGSPAGKDAAGAAAVTVVTAAGAEVGAAAAETRRGGEPVDGLFEAVARPSALRIAGMEGSLGGSSHSRNVSGVGDVSAGIGGGGGDSAKGVLAARNSIFNASRRSNRVSASNAPVIDGDASVASGAAAAVRAGPPALAERWSASGATSVGAWGSSTAGAARSTGSGTAPLALVSFDAAAGGGASVAAASAAAGAAVTAAAATSAAAGSRPGSAAPRRSESGAGSLASALLGPFRRGGVGGGSKASSSAASMTTAAAAAATTAVAAPGPTSSSRLAEPAELQGPANGSASAPPELHPIVELRDNDLFGDSTYSAAITTPPLTPDAGGSGAAAPGRANAALPAPHLVYSGSLRVSGADYAAAAVLGSPAEGGGTVGAAADVASAAAAGGALVTSAAVTTAAAAKEERRSPLAATPPGWRGSRDGAAPTIAGDVVPTLPAAIIASPPPPRVEPLGMCMPSISRRQSRAGGPGSSSLSEAAPAAVMVAGSATSGAPPLKPLVVPEHPAEAEEGHNAQVLDRDHLPAEPEADPHTHRSALAGSMAAFAAALELHDSFTGGHASPNRLSGGGGGAGGVWYGSPRLPGTLAGSPSASRDAARHSQKQRRRKSLIMADGGAALPHDGVASPRQLSDDESEALAAAATAAAATLLARKSGGSAATQHLAGRSRLGFAGVTSGGDVAGHMPAPPPAPLPPAPAPPPAAQPANDGMAGAAAAPEPPQQSAAARMVAATKAFAEAFAAMEHARAQKLAAQQQQQQQEQQPQPEEPPAPLSQRTSLSGAGDGDPAGAGLPAAEPPAPPSRAESSRRTTYDGAATLNRQASERPPSGRPPSGRPPSGRPSASGAPSRLPSAAQRNANSIGRRESATGRIDAGTTAPAVGDGARPDAAQPLAVLGSPAAGASPQLQATALGTLQNAASLSRTDSRGARKELSSVTTAVHAITATTKLAAASASTAAAAAAQAAAAAAVAPAAAPAAAPAVGFAPYAASGGSTSISSTASPSSPPSTHRCQQAPPTVAIDEKDARVAAGAAGSPTATQLPAIRVPSSSDGEGEVHRAATGAAAAASPSGVAQGGAAKAPPLVIGSPSGVAAFGIGGGAKLGSPAADPVLPIELQVRRVEVYERYGQLFEEFRGGKLTAATFQGALLVNAVVPAVLLAAQAGADMAAGSPGAKATNIALLSVKALYALYMSLVLPFSNAITMAAELVCSWLEAAVCAGLVALQWHAGAKGISSAMVVCEVLVIALQIVRILLTSAIPCIIIVWEWCHAHCCLRCRRHKSDDGTDAAAIGAIGAGGRAEGGWDEEGATGRAAIAGGHEKRSG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WNX8</accession>
    <name>A0A835WNX8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">STI1/HOP DP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_000209</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000012">
        <property type="protein sequence ID" value="KAG2450105.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WNX8"/>
    <dbReference type="OrthoDB" id="539167at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041243">
        <property type="entry name" value="STI1/HOP_DP"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171:SF9">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17830">
        <property type="entry name" value="STI1-HOP_DP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="STI1/HOP DP" evidence="5">
        <location>
            <begin position="155"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="227"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="260"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="293"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="58"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="70"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2450105.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="359" mass="37717" checksum="DC4648C2125FB825" modified="2021-09-29" version="1">MFPGMPGGPGGPGGAGAFDFSALQSALNDPSIKQMAEQIANDPSFKEIAKQMQESFGAMMGGMPQGPGAPGAEARAAGMPGMPPGMPPGMPGMMPGMMPPGFDPSKYMEAMQGMFQNPGFMQMAEKLGKSIIEADPNMANMMKAMQDPDYKTKVEDALKGLKDDPELKPILEELESQGPAAMMKMWNNPEVLSKLGKAMGGVFDFEGALEAGEGGEGAEGEEEEEGEVEETVHGAASAGDVELLKKLIAEGANVDEADEEGRTALHFAAGYGELDCVHVLIEAKAKLDAVDTNQNTALHYAAGYGQAESVKILLSNGADRTSKNLDGKTALEVAELNEQADVIAALKEEVKEEAKEEAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WP66</accession>
    <name>A0A835WP66_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_004314</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000009">
        <property type="protein sequence ID" value="KAG2451046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10252171at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1627"/>
            <end position="2122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="198"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="450"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="646"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="805"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="971"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1118"/>
            <end position="1154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1173"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1247"/>
            <end position="1296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1310"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1466"/>
            <end position="1485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1534"/>
            <end position="1555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2046"/>
            <end position="2089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="198"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="457"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="646"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="679"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="805"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="838"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="868"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="982"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1007"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1124"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1173"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1310"/>
            <end position="1321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1352"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1374"/>
            <end position="1384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1475"/>
            <end position="1484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1534"/>
            <end position="1550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2048"/>
            <end position="2089"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1654"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2451046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2145" mass="213533" checksum="E94D4B0B4E4857CD" modified="2021-09-29" version="1">MDGEAFILLPGARLELRDLTVLLPPLPLLDSRTLSAEAAAGAGAGAGVLSHILSYAPPGGGGALGSPDSARNGVTVLLSGVRLVLSTEGELRFFTQQLCSPASWRYRPPPPSPPLQARLEAATVGAGAGVGDAAAAGDWVGENTAAAAAAAARIQVLGGVVQYDAGTMPLGGGGGRAPARLLNCSVTCCLAAADAAAGDGSSSSNGSAGSSSGSTDVVTTTSSSYGPSAPYVCSAVTTATRSVSELLGLAAQLLLATSGGGTVYISLAADVISLDVAAGGQQQQQQQQQQQSQEAGAMVVVPPGAMLALLGRPAPPPPASSAGRRATQIDWGGGAVGAIRPAVAFSPGQPVGVVLLRDLVMTGLPYPAALVRGPEDLLAGWLHVVRKPSGGFLPSVGVVAERCTLVLAAQELAFWRAAAAAEAAGEPTATAWRKEHFGFGWRIIGASPAAETPATTSGGGGGGGGAQQQEREQQQQLLRIDQLLDRKATRFTNLTFMTLPAAVTQVGVTVSPGAQAAAAEWPILKSAIVVDGGGGAGSSSSSSIGGGSAANATAAQSQQQALLLQPRLGRFRTSGSYYTYIENWFEVATAIGDRFMLLDPAAGFERMRRPGAARQQPPPQLPLCAMSLNNTSNSVGASFFTNITSSNSSSNSSSNSSSSNSSSSSSTGAGSVSGSSNTDGGGDTGSGDSGGGGSGGGCSAWARSDVVLYSTLPRSIYEWSEPVVSANITLLPVPAAQTRMRAFWDMQGSVGAHVNLRIADGATLTLYGIVLYNLPPVGDTWEDGSSLVVAAAAAPAAAGGNGGGLPNIGGGDSGLPNIGGTGPDMGSTGPMIGTTGPDAGNTGDDQAGAAAAAEGAREEHPSPSRAQSPPPAIPPPSLPPALPQPPEQPPAQPPQQPPSQPPSPPPPLPPSAVQSALATLALPLWQFKMNRASTAQQQQQVPVQLINVTLVVSPAELALLRRTLQAAGRLLLPEQPPPPPQQQQQQRQAAAGGAVGSRRAFQRRQLRQQATSPAPAADSTTPPATSAAVPAAAAASATSSTTAVTSSSCPRALLLSFAAQSAVDWATEDALHFSTLAHYGWRGEDITVTSALPDDAPSRRYAWPGGAADDGSAALSPLLEAACPSPPPPPSSPPPNDPQLQAAGAGSTAADLRAATPPAAAAAAAAAASGVGPSTAAAAGSSSALGGGSSNSPSPSALVAEASAGGSSAGSGGSHTTVIAIAVPIAVVGSALLAILSTLAIMRNRRRRRHQQGGNSGVFAVDKTGGGVKGTGTCATAGEQKDESSVTGNSDNRESTYPGLARVLDVHPAATSSAGGSSNPLASPAATATDEQRAKGVKQAAAPSPGGGGTSSSGSHHVTGNNSSGGSAAAASGPGAGGGGGGVGGATWHNSRLAAIASATEGFSGSLGDNNNAADANTPIVGRLLEMARAPSSSTLLPGEGGTAAYATATSATSDYTDAAAAATAAAASMPSPSRPDDGGRDLRTAPSPLALMAAAAAYSEELQAYLAKQERRLEVAAAATAAAVTGASIQAAGGGAAASSSTPGSSQQGNASSPMAAIRTIRLSRNGNCTRRGLPNGRSTRASWTGGGAGAGAGAGGAALVRAIQSLGAALEEADVAREGAADDEVTLLLPLGAGGFGSVYLGTWRGLPVAVKVLVVQDELVGEEGRQRQRAVLEAAIGSSLSHINVVSTFAYDLKPLAVQFDPQQQQQQQQQQQQQLGGAAAAGVAAAGGGGGGSGGSDVYQLCILQQYCIGGSLKAALDDAPNSGLHLGVLLDPAFSSSSSAAASGLAAARRAAATATALYLAIDIALGLRHVHAAGIVHGDVSSGNVLLAKREEEEEEEEEGAKVASAGPLAGAGVGLLQSVQEELLGPGPKGSSAGEGPALPAAAVGDEVERRVCARLAACGAFKPPLVAKVADFGLSVRMDGSRTHASGMFQGTPLYSAPEVVADGRVSRASDVYAFGVLLLELLLGRSVGSLWCDPHLLQQLAARLQQQQHPCAASQQAQQQQQQQQQVQQQRLLQAAMTPGPHQAASLAQILLMDKTDGDGQQPMQQQEQDQEQQPAAFTAPPPAHAALHRSAAAATHSPGGLPGPLSQLLLSCLAAGPSCRPSLDQVLEQLTACVEQLEAAVPQRSRRVGGPKRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WP71</accession>
    <name>A0A835WP71_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_000326</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000012">
        <property type="protein sequence ID" value="KAG2450225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WP71"/>
    <dbReference type="OrthoDB" id="545609at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="81"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="37"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="135"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="212"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2450225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="346" mass="35748" checksum="746E1A6895C252B7" modified="2021-09-29" version="1">MEFTGLSDSPKAARKAAERTRQRKKGAFAPRPKQVQLQSLQAKLDELLEQYKAAEAENKRLKERLTLIEVVLPTREHQAKIAAAAGSRGSSGALPRPLQATPAPAGTDGGPGASPGLSPRYPLSPSPSPATGPDAASSVSASTPSGSGQAANNRAGEEAACAQSRSPQPLPGPQLGPPASGGAGLQNLQHPRALASEPPTVLPGQTPPQPQPLSLSLQHAGHAASAAVAVAAKRRPGRRPEAAAPPPQPPPPGDDDGLSAAWRALWMAWVRDAALLIVAHDARPGGGYWLQRLDEACTRLKTQVVQLGLKHPELIADDMPQLNLGEVWGLCGAGAEPGAQGPGRAW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WP92</accession>
    <name>A0A835WP92_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_004766</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nucleolus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WP92"/>
    <dbReference type="OrthoDB" id="440760at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006396">
        <property type="term" value="P:RNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05791">
        <property type="entry name" value="S1_CSL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.140:FF:000223">
        <property type="entry name" value="Chromosome 1, whole genome shotgun sequence"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.100:FF:000157">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.100">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039771">
        <property type="entry name" value="Csl4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019495">
        <property type="entry name" value="EXOSC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025721">
        <property type="entry name" value="Exosome_cplx_N_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686">
        <property type="entry name" value="3'-5' EXORIBONUCLEASE CSL4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12686:SF8">
        <property type="entry name" value="EXOSOME COMPLEX COMPONENT CSL4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14382">
        <property type="entry name" value="ECR1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10447">
        <property type="entry name" value="EXOSC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110324">
        <property type="entry name" value="Ribosomal L27 protein-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="S1 motif" evidence="4">
        <location>
            <begin position="71"/>
            <end position="150"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2450255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="197" mass="20887" checksum="AE94C05FC5A4F55E" modified="2021-09-29" version="1">MSAADAQGVCVGDRLGTTDTYAAGEGVFVRDGFVIASVVGFKRVEVPAAAGEKPTLHVASRDTLPLVPKPGDIVTVKISRVAQTAAHALIMCVGRQALSTEFKGVIRQQDVRSTEIDRVVIYDCFRPGDIVRAEVVSLGDARSYYLSTAKNELGVVYAKSATAGAAMVPTSWVTMQCPDTQAVEKRKVAKLESLVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WP93</accession>
    <name>A0A835WP93_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">GPR1/FUN34/yaaH family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_004692</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the acetate uptake transporter (AceTr) (TC 2.A.96) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000010">
        <property type="protein sequence ID" value="KAG2450858.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WP93"/>
    <dbReference type="OrthoDB" id="2013617at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015360">
        <property type="term" value="F:acetate:proton symporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071422">
        <property type="term" value="P:succinate transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000791">
        <property type="entry name" value="Gpr1/Fun34/SatP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047623">
        <property type="entry name" value="SatP"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF038013">
        <property type="entry name" value="AceTr_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30178">
        <property type="entry name" value="INNER MEMBRANE PROTEIN YAAH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30178:SF3">
        <property type="entry name" value="SUCCINATE-ACETATE_PROTON SYMPORTER SATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01184">
        <property type="entry name" value="Gpr1_Fun34_YaaH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="14"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="79"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="131"/>
            <end position="152"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005587"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2450858.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="169" mass="18758" checksum="F78D98DE41745D98" modified="2021-09-29" version="1">MLMFITTEWTDKQFLPTVFCYAMFYGGFGQFVAGALELIKGNTFGGTAFASYGAFWMGWFLLEYLSWTNKAMFPGVQSGKSLWCGLWAVLTFGFFIVTCRKNGCLMTIFSTLVITFSLLSGGVWSHDCEHAAGYFGFFCGASAIYAAFAFLYKAELGILLPGVRPVHFI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQY8</accession>
    <name>A0A835WQY8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4 12">Cysteine synthase</fullName>
            <ecNumber evidence="4 12">2.5.1.47</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HYH02_003882</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 12">
            <text>O-acetyl-L-serine + hydrogen sulfide = L-cysteine + acetate</text>
            <dbReference type="Rhea" id="RHEA:14829"/>
            <dbReference type="ChEBI" id="CHEBI:29919"/>
            <dbReference type="ChEBI" id="CHEBI:30089"/>
            <dbReference type="ChEBI" id="CHEBI:35235"/>
            <dbReference type="ChEBI" id="CHEBI:58340"/>
            <dbReference type="EC" id="2.5.1.47"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 10 12">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="2">Amino-acid biosynthesis; L-cysteine biosynthesis; L-cysteine from L-serine: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the cysteine synthase/cystathionine beta-synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.5.1.47" evidence="4 12"/>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451276.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WQY8"/>
    <dbReference type="OrthoDB" id="10259545at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004124">
        <property type="term" value="F:cysteine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006535">
        <property type="term" value="P:cysteine biosynthetic process from serine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd01561">
        <property type="entry name" value="CBS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000067">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1100:FF:000130">
        <property type="entry name" value="Cysteine synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1100">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005856">
        <property type="entry name" value="Cys_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050214">
        <property type="entry name" value="Cys_Synth/Cystath_Beta-Synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005859">
        <property type="entry name" value="CysK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001216">
        <property type="entry name" value="P-phosphate_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001926">
        <property type="entry name" value="TrpB-like_PALP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036052">
        <property type="entry name" value="TrpB-like_PALP_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01139">
        <property type="entry name" value="cysK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01136">
        <property type="entry name" value="cysKM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10314">
        <property type="entry name" value="CYSTATHIONINE BETA-SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00291">
        <property type="entry name" value="PALP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53686">
        <property type="entry name" value="Tryptophan synthase beta subunit-like PLP-dependent enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00901">
        <property type="entry name" value="CYS_SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 12" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="8 12" id="KW-0198">Cysteine biosynthesis</keyword>
    <keyword evidence="7 10 12" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Tryptophan synthase beta chain-like PALP" evidence="13">
        <location>
            <begin position="7"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="75"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <begin position="179"/>
            <end position="183"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="267"/>
        </location>
        <ligand>
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </ligand>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="11">
        <location>
            <position position="44"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004962"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012681"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00047931"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR605856-51"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU003985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF00291"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG2451276.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="322" mass="33864" checksum="93021536EE38B110" modified="2021-09-29" version="1">MNIATDVTELIGKTPMVYLNKVATGTHAKIAAKLEIMEPCCSVKDRIGYSMISSAEKEGLITPGKTVLVEPTSGNTGIGLAFIAAARGYKLILTMPASMSLERRILLRAFGAELVLTDPAKGMKGAVAKAEEILASTPDAFMLQQFQNPNNPKVHYETTGPEIWSATDGKVDILVSGVGTGGTITGTGRYLREKKPGVQLVAVEPAESPVLSGGKPGPHKIQGIGAGFVPAVLDTALISEVVQVSSDDAIDMARRLALEEGLMVGISSGAAVQAAIKVASRPENEGKLVVVVLPSFGERYLSSVLFQQLRDEASKMTFEPSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQZ1</accession>
    <name>A0A835WQZ1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">ARID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_002714</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452474.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="533185at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009725">
        <property type="term" value="P:response to hormone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022702">
        <property type="entry name" value="Cytosine_MeTrfase1_RFD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028942">
        <property type="entry name" value="WHIM1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028941">
        <property type="entry name" value="WHIM2_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460">
        <property type="entry name" value="CYCLIN-DEPENDENT KINASE INHIBITOR-RELATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12460:SF38">
        <property type="entry name" value="KINETOPLAST-ASSOCIATED PROTEIN-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12047">
        <property type="entry name" value="DNMT1-RFD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15612">
        <property type="entry name" value="WHIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15613">
        <property type="entry name" value="WSD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ARID" evidence="5">
        <location>
            <begin position="1468"/>
            <end position="1568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="229"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="441"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1217"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1422"/>
            <end position="1459"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1619"/>
            <end position="1657"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="1180"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="18"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="265"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="309"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="452"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="1224"/>
            <end position="1233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1254"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1295"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1630"/>
            <end position="1657"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2452474.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1657" mass="182297" checksum="948480A3A79E920A" modified="2021-09-29" version="1">MADTQEEAGPGQVPPPEDGAAAPEAAAAETDAPLRTLNEFTIVNTASGNAPVSLEALATFPPGSVIAVGSCPPVDASPGSTKALTLQTQPITDWVISYGNPAGVWVCTEKAWYRLEEPSPAYAALFAPIQRKLDFCLRAAAAIASNPTVTLHGAVAALLQAGQHPGDSQTVYNVDDLKQDTPFVLPQLVAWVKSNNLATPPLLVELQPIAAAVKQQQAQQERAALLAANPPVAHVGGGRGRGRGKHEDDHEKAPGRGRGRGRGRGAAAAAAAAAAAAEKEAAAGSHAHRTRSLTPGGPLPIGPPGDDGCAGDEEPDLDDYDDWDDFGEEDVEGDSDLSKEGDEMGEAMDAGLNEEERGELKRQRKEAKWERRRAEHLAKLAAADSERGDPPEAVADWRVDPDMVPEVLAVWEMAMTFAYMLQLPAMPLRALEAAIMPAPLPQRSADGKPLLAKKEDTKVKTEEDGDAGEADKAEQPDVLYDANSMVDYNYIASAALLRDLHAGLLRMVDGHAPRKQELPQESKLMADEAKVENWVERTAVAIHNAPVDLVGPEAKAIAETLRTREYVLLPPRHKLTIMRALIHMALASDVLREHINARVEMFAVKAQLLAARGVNPATGDDGASRRAVDDLAQPLLPSGPVEAEDPDFWIRWMDSVKLGLRKPVGKDYRGRRYWALGANAGAWRIFVENPTDSSWGWYEGEKLEQLVDWLKRGNISREAPLLRVLESIQIPKKLTHGRVHEPGEVAEADLARAAIPWTPEDMEIRRASGYRHLTAPLLKGDLNKMPHQPGIPRLPLIIEDRVCNAVEAIMGEVDWWMQASAWPKTLGELLDLLRFTYRSAREALEDDPECSNPETQALARFSGSEVLLALEDMLFQVGALNDTWKVQLRDAWQASLRNPNLTAREVSLHVLALQQFLTTTDSPFVLTRAAFQKRINEARCPLYFPGPNEEVVVMRSGIFSHIDKFSQVARSHKDEKWLNELAEMRARVDNMHCAQRYRVACLSYRTYPLLEQSSEAAAVAAAAHAAAQAEARAEGGEAPETSGQPYAPPSRPPCMWMLLTPLRAPLPRFEQAQGQVVLPLYIENTLPNFVIRGDIFDKAREKGWAPGDRCRMYVGGKQGAKVSGSWYKGKVIHVGLPTAPEHQDFDPWESVVVEWDRQGLENTQARVCPWDLEVDPEAERRLAEERKRKAEEEAAAAAAAAAAARAERLQARDRATKVVVQQEMGEEDDDEYVPTDGSSSDSDESEGSEDSGAPRRRGRPPPRKKQSRGNARGGSGRGNDDPRQQQQHGGGGGNQSQQAVLEQQRRAQLLQQQQQQQRQAQGNNNLLAQAIQQQPLLGQIYQQIAHYPLAQQVQVLQNAGQQNTQQGLLARQLLQVLVQQQQQQQAAQQQQQALQQQRQQELLLQQQQREQQQRQLLLQQQQQQQQAAMADPDDNGRPVAPDLLSPPLQSRNPGGRRQAVPHHLLQAMPQREPFHYMLVNWYRQRGVLRYRLPQLGGRDVDLHKLFLEVHLRGGYDVCVLKQLWPELCASQGVHPQTPASNAQPNTPAAAALRAHYERCLLDFEDYVTSGQFETDVQTNRLPPLDRLLEIPGAVPAVKREASGYGMQQGGNDVRMQQLMMQQQQQQQQQGNGGYGGGQGYGGQGYGGGGGGWQQGMR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WTB7</accession>
    <name>A0A835WTB7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_002409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WTB7"/>
    <dbReference type="OrthoDB" id="540004at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861:SF3">
        <property type="entry name" value="PUTATIVE (AFU_ORTHOLOGUE AFUA_2G14390)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43861">
        <property type="entry name" value="TRANS-ACONITATE 2-METHYLTRANSFERASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase" evidence="2">
        <location>
            <begin position="34"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2453077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="212" mass="22791" checksum="900CD0D84C7DBF7E" modified="2021-09-29" version="1">MDASVWDKKYSEEEFVYGQAAERYLNQVPGGALVVELASGEGRNVAYLAAAGHRVIAVDFSQAGLDKTMALVAGRGGGSATARVTPVLADMTAWAPPGGPGSVDAVVLSFCHMRAADRPRVMAAVVEWLKPGGLLIQEVFHPSQVHKGYRETSGGPHDPTMMVELQELRSQLGDKGGEELEGEELEYVLEEGKLHNGMGAVTRYVWRKDPAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUD3</accession>
    <name>A0A835WUD3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_002240</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the peroxisomal membrane protein PXMP2/4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452896.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUD3"/>
    <dbReference type="OrthoDB" id="5345392at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007248">
        <property type="entry name" value="Mpv17_PMP22"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266:SF21">
        <property type="entry name" value="ACT DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11266">
        <property type="entry name" value="PEROXISOMAL MEMBRANE PROTEIN 2, PXMP2 MPV17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04117">
        <property type="entry name" value="Mpv17_PMP22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363053"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2452896.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="281" mass="30457" checksum="7904AC42F0A8AC7B" modified="2021-09-29" version="1">MPAIRGALQLLKLPFVKVGTAYNNVAVKAPMLTGVVTTVVKTSAADLFAQKVVEGRDEVDWRRHSMFVMFGFGYLGCWQYYLYNNLFVRWCAPITRAFGHAGSAPVKVFIDQCIHHPLLYFPCFYSLKGMVEGRPLEESFADYKEHLWDNCKALWMIWVPAQMVNFTVVPLHLRIPFVAGVSFAWTVVISVMRGAMDKHPPTKEEAAAPSMVSQAAAAAASAASGVARTSVGSLQPLLNTATASADSGSLEDGSSSGPVGLQQLVAGNEQVDSASAPMLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUE4</accession>
    <name>A0A835WUE4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Elongation factor Ts, mitochondrial</fullName>
            <shortName evidence="5">EF-Ts</shortName>
            <shortName evidence="5">EF-TsMt</shortName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="primary">EFTS</name>
        <name evidence="9" type="ORF">HYH02_001845</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4 5 6">Associates with the EF-Tu.GDP complex and induces the exchange of GDP to GTP. It remains bound to the aminoacyl-tRNA.EF-Tu.GTP complex up to the GTP hydrolysis stage on the ribosome.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="5">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 5 6">Belongs to the EF-Ts family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453632.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUE4"/>
    <dbReference type="OrthoDB" id="277235at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070125">
        <property type="term" value="P:mitochondrial translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd14275">
        <property type="entry name" value="UBA_EF-Ts"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.286.20:FF:000001">
        <property type="entry name" value="Elongation factor Ts"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.8.10:FF:000001">
        <property type="entry name" value="Elongation factor Ts"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.286.20">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.8.10">
        <property type="entry name" value="DNA helicase RuvA subunit, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.20">
        <property type="entry name" value="Elongation factor Ts, dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00050">
        <property type="entry name" value="EF_Ts"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036402">
        <property type="entry name" value="EF-Ts_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001816">
        <property type="entry name" value="Transl_elong_EFTs/EF1B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014039">
        <property type="entry name" value="Transl_elong_EFTs/EF1B_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018101">
        <property type="entry name" value="Transl_elong_Ts_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00116">
        <property type="entry name" value="tsf"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741">
        <property type="entry name" value="ELONGATION FACTOR TS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11741:SF10">
        <property type="entry name" value="POLYPROTEIN OF EF-TS, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00889">
        <property type="entry name" value="EF_TS"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54713">
        <property type="entry name" value="Elongation factor Ts (EF-Ts), dimerisation domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01126">
        <property type="entry name" value="EF_TS_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01127">
        <property type="entry name" value="EF_TS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 5 6" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 5 6" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Translation elongation factor EFTs/EF1B dimerisation" evidence="8">
        <location>
            <begin position="105"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="domain" description="Translation elongation factor EFTs/EF1B dimerisation" evidence="8">
        <location>
            <begin position="303"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="220"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="220"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="233"/>
            <end position="245"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00025453"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="HAMAP-Rule" id="MF_03135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="Pfam" id="PF00889"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2453632.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="466" mass="50137" checksum="EE936344FC44C1D5" modified="2021-09-29" version="1">MCVFYAPSLADISAAEVKALREKTGAGMMDCKKALAECAGDAEAAAEWLRKKGLSGADKKAGRIAAEGAVARYIHPGSRLGVLLEVNCETDFVAASEKFQSLVNELGMIIAATDCICVSPEDMPEEVLAKEREVEMGKEDLANKPEAIRAKIVEGRLQKMRDQSALMNQATLSNPDKTVSELVKETIAAVGENVKIRRFTKYRLGEGIEKKSNDFAAEVAQQTQAKAAAPAAPKKEEPKKEEAPKKPTVAVAAGAVKELREKTGAGMMDCKKALAENEGDMEKATEWLRMKGLAGADKKAGRVAAEGVVASYIHPGSRLGVLLEVNCETDFVAASEKFNELVNYIAMGIVAGQNVQYVSADEIPAEVFEREKQLEMAREDLKGKPDAIRAKIAEGRAKKIATEMCLLDQPFLTDPSKTVAEAIKEAIAAIGEKISVRRFVKFQLGEGLEKKSNDFAAEVAAATGQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUF6</accession>
    <name>A0A835WUF6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_002266</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452926.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUF6"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051034">
        <property type="entry name" value="Mito_Enoyl-ACP_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43981">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43981:SF2">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0521">NADP</keyword>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="286"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="3">
        <location>
            <begin position="181"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2452926.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="313" mass="32346" checksum="CC6C27EA2C2D8803" modified="2021-09-29" version="1">MCHAAPRTPVSAYVQAELDRLHFHARPRLALDAVGGDSAARLADALAEGGELVVYGAMSGRSPALTWQALLFRDLRVRGFNLRRWAAAGVPPPPPAALASAAAGSAAFGGGLSGGSSGGPVRYRAALEALGKLVAAGMLTVAYTEYDLTEFPEALEHALERGRDTKVLLSCGRCGPAAEMLAALQQQVQQTQVHQQQQQQQQQQQQQQQQVQQVQQVQQLGAGVVPLAGASDVEVEEEREKPDVVAAAAAQPIPTGAGSGAGKQVKFALELGDEVEAVAGGVGVRAGLKKGKGGAQRGGKPVVISTADATSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVC0</accession>
    <name>A0A835WVC0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_002108</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453903.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVC0"/>
    <dbReference type="OrthoDB" id="551059at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" evidence="1">
        <location>
            <position position="34"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2453903.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="179" mass="18780" checksum="930CE7C27FDB70D3" modified="2021-09-29" version="1">MLNPEHLQIQANLGAGGFARVFRAKYEGLEVALKVLAPANIHPGNPAAAEEYATAKELFLREGRSLLGIRHPHIVRCVAMGPLPVASVPGLLGSGRSLAQHHRHHKPHTAAAAAAAAASSRTPGGGAAAPPNASLLAPAMALEMCEPYTPRQLIMRSMATASKAYSTTTALEWLMQVCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVH3</accession>
    <name>A0A835WVH3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_000893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2455068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVH3"/>
    <dbReference type="OrthoDB" id="5034579at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2455068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="171" mass="18643" checksum="93EC91137602E206" modified="2021-09-29" version="1">MTTSEVLSPPPPSQVASLAQPQFNVEALQSFPMPLVADVVNTENGDVASFARSSWHKESGKAGAFGLPTMLDMKAEALEQVQLDTWSAQPVDRGPAAAAPDPKLLRSWQYQVTGKLATAQVLVDVKAEHIKSGGPMGMKQEAIKHIMRHKPDDTFYVVDLANVQRMFKVMD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVH9</accession>
    <name>A0A835WVH9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">procollagen-proline 4-dioxygenase</fullName>
            <ecNumber evidence="4">1.14.11.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HYH02_000905</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="14">
            <text>L-prolyl-[collagen] + 2-oxoglutarate + O2 = trans-4-hydroxy-L-prolyl-[collagen] + succinate + CO2</text>
            <dbReference type="Rhea" id="RHEA:18945"/>
            <dbReference type="Rhea" id="RHEA-COMP:11676"/>
            <dbReference type="Rhea" id="RHEA-COMP:11680"/>
            <dbReference type="ChEBI" id="CHEBI:15379"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:30031"/>
            <dbReference type="ChEBI" id="CHEBI:50342"/>
            <dbReference type="ChEBI" id="CHEBI:61965"/>
            <dbReference type="EC" id="1.14.11.2"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>L-ascorbate</name>
            <dbReference type="ChEBI" id="CHEBI:38290"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the P4HA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.14.11.2" evidence="4"/>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2455084.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVH9"/>
    <dbReference type="OrthoDB" id="420380at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031418">
        <property type="term" value="F:L-ascorbic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004656">
        <property type="term" value="F:procollagen-proline 4-dioxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.620:FF:000002">
        <property type="entry name" value="Prolyl 4-hydroxylase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.620">
        <property type="entry name" value="q2cbj1_9rhob like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005123">
        <property type="entry name" value="Oxoglu/Fe-dep_dioxygenase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045054">
        <property type="entry name" value="P4HA-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006620">
        <property type="entry name" value="Pro_4_hyd_alph"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044862">
        <property type="entry name" value="Pro_4_hyd_alph_FE2OG_OXY"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869:SF238">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE 6-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10869">
        <property type="entry name" value="PROLYL 4-HYDROXYLASE ALPHA SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13640">
        <property type="entry name" value="2OG-FeII_Oxy_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00702">
        <property type="entry name" value="P4Hc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51471">
        <property type="entry name" value="FE2OG_OXY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0223">Dioxygenase</keyword>
    <keyword evidence="13" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="11" id="KW-0408">Iron</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Fe2OG dioxygenase" evidence="15">
        <location>
            <begin position="52"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001961"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004648"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00006511"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022964"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00049169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51471"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG2455084.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="180" mass="19712" checksum="9633302F5BAD5723" modified="2021-09-29" version="1">MVKSSVVDNESGKSVDSEIRTSTGTWFSKGEDAVISKIEKRVAQVTMIPLENHEGLQVLHYHDGQKYEPHYDYFHDPVNAGPEHGGQRVVTMLMYLTTVEEGGETVLPNAEQKVTGEGWSECAKRGLAVKPIKGDALMFYSLKPDGSNDPASLHGSCPTLKGDKWSATKWIHVGPIGGHH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WWG2</accession>
    <name>A0A835WWG2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_000520</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNAP-25 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WWG2"/>
    <dbReference type="OrthoDB" id="19261at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd15841">
        <property type="entry name" value="SNARE_Qc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15861">
        <property type="entry name" value="SNARE_SNAP25N_23N_29N_SEC9N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044766">
        <property type="entry name" value="NPSN/SNAP25-like_N_SNARE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305">
        <property type="entry name" value="SYNAPTOSOMAL ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19305:SF9">
        <property type="entry name" value="SYNAPTOSOMAL-ASSOCIATED PROTEIN 29"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="141"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="70"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="231"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="13"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="165"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2454682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="280" mass="31267" checksum="A642BE6620CDA9B9" modified="2021-09-29" version="1">MFGKKNASAATVVRERKEEEASRNELFAGQQEEIVIDPTQLPLEQQTTDQLVRTAQQTHKETTQVAQRALKVVEESKQIQAETMKNLEEQNKKMYDIHNRMDDMNEELTYAEKLLSYMRRCCCCWLCDSCTGADPEEQRKRAWQRRVAKGKTAVPAGRGPPPQPGRGGAGEKAANGNGGGGGGGRAQGGTYRNPDIRLPDEHRAAEMGLHEETRKQNEVIDQIHAGLEHLLEGARGMHEELAQQNKELDALDSKATATRDRINDVNKNSQLRNMAGIRPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WZP9</accession>
    <name>A0A835WZP9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_000977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2455160.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WZP9"/>
    <dbReference type="OrthoDB" id="547828at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="206"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="251"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="284"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2455160.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="307" mass="31836" checksum="37D269E07CE86B9D" modified="2021-09-29" version="1">MQVQTRSTVSAARPVGASARRVSLAAVQQVKQASTTAAAGPQEEIYIGFVKEEGFGDRTGRKGRVIKDDPRKYPSRDWVGVGGWAGGEAGLWQLREQVTKEKESKKPAGPAPSSPLPVKIPKAPAGKAPVYIGFVKEEGFGSREGKRGRIVVDDPRKYAGKEDLGPLAGVTGGFAAGEVGLKQYVATGDVKLRAPGQPGPKQFSPLTLAGAVALAGAVGGVVLGLVNDAGEIEQTRELLQRAATDENTLKYVAVGAAAVGATAVLVAINNAVRALQRQLEENGGRVVVSAAFLAVVLLVAKGIIESQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B0Z1</accession>
    <name>A0A836B0Z1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DNA polymerase delta subunit 3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_009082</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000029">
        <property type="protein sequence ID" value="KAG2444143.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B0Z1"/>
    <dbReference type="OrthoDB" id="514823at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043625">
        <property type="term" value="C:delta DNA polymerase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003887">
        <property type="term" value="F:DNA-directed DNA polymerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006271">
        <property type="term" value="P:DNA strand elongation involved in DNA replication"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1904161">
        <property type="term" value="P:DNA synthesis involved in UV-damage excision repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006297">
        <property type="term" value="P:nucleotide-excision repair, DNA gap filling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1030.20:FF:000002">
        <property type="entry name" value="DNA polymerase delta subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1030.20">
        <property type="entry name" value="DNA polymerase delta, p66 (Cdc27) subunit, wHTH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019038">
        <property type="entry name" value="POLD3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041913">
        <property type="entry name" value="POLD3_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17598:SF13">
        <property type="entry name" value="DNA POLYMERASE DELTA SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09507">
        <property type="entry name" value="CDC27"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0235">DNA replication</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="153"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="428"/>
            <end position="492"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="160"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="171"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="246"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="315"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="372"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="383"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="400"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="434"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="465"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00017589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022705"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2444143.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="492" mass="50266" checksum="30AC96D520D5FCFC" modified="2021-09-29" version="1">MPSDESAEIVQELQGLVHDELKVLSYKWVARQYSIPANRAKRVLFQFAEQQRDKVRTVYLVSGWTKQDPPSHVHQLVEAGQLQVCREGFGEVTGMHVYSVAPNQATNPDTLWQHTHQQSQQLLKEITSGQPSASADTFRTNSCSAVRFTAQPAEAQPLRPSAPAPAPAPVAKPAAAASKPAPAPAAAAQPESRSPAAIAKAAPPAPAAAGPSGSSPPKAAAGSPPKGGKAAAAAGKGSKTLANMWAKGPAKPKAAAAAPAAEAEPAAETPAPEVKAEPVDEPEEDDGGFVTANRGKKRRGAQIEDSDEEQEAAKEPAAAQQQAPPADEPAAGGKSKGKGKSSAATKENKGEKGGKRAKTSAVKEEAPAVAMEVEEPVAEEQQEPAAAPVSAPPAWATAGAGAGSGGPGSRGRKVTRTYINDDGEEVTEEVFEDGPAPLQPQQQPAVAPPQPAAKAAALKPPPKAAAPAVAGKGKGKAPAAGQKSMTSFFAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B2A6</accession>
    <name>A0A836B2A6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Bidirectional sugar transporter SWEET</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_008735</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mediates both low-affinity uptake and efflux of sugar across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 12">Cell membrane</location>
            <topology evidence="1 12">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the SWEET sugar transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000027">
        <property type="protein sequence ID" value="KAG2445268.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B2A6"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051119">
        <property type="term" value="F:sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000004">
        <property type="entry name" value="Sugar transporter SWEET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047664">
        <property type="entry name" value="SWEET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004316">
        <property type="entry name" value="SWEET_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791">
        <property type="entry name" value="RAG1-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791:SF224">
        <property type="entry name" value="SUGAR TRANSPORTER SWEET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03083">
        <property type="entry name" value="MtN3_slv"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 12" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="24"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="64"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="94"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="122"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="152"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="181"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="208"/>
            <end position="229"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU910715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2445268.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="253" mass="27382" checksum="93149171F4C1D77C" modified="2021-09-29" version="1">MTPWTGRSLLDDDDDDEPFDMKKLFLHHLAPGLGCIIAFLMFVSPLKTVLQVRANKHLGDLNPLPLVAIIANCAGWLIYGCINADPYVIAANEPGLLLGIFMTVSCYGFADPKARDLMLKALMFFSVLLSCVGISIALFIEDDEWASKTAGYTAVFILLCYYGAPLSTMAEVLRSRSSASLFWPTSAMNTVNGLLWVAYGTAVSDPFIAIPNAIGAAFGVIQIGLIQIYPAKKVSTPPADDVEPLIHEGRHVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3C2</accession>
    <name>A0A836B3C2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_008457</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000026">
        <property type="protein sequence ID" value="KAG2446465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3C2"/>
    <dbReference type="OrthoDB" id="360390at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003107">
        <property type="entry name" value="HAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008847">
        <property type="entry name" value="Suf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204">
        <property type="entry name" value="PRE-MRNA PROCESSING PROTEIN PRP39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR17204:SF25">
        <property type="entry name" value="RRM DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05843">
        <property type="entry name" value="Suf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00386">
        <property type="entry name" value="HAT"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="4" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="6" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="8">
        <location>
            <begin position="744"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="611"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="821"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="39"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="50"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="611"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="633"/>
            <end position="643"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="677"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="702"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="724"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="825"/>
            <end position="861"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="879"/>
            <end position="898"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2446465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="956" mass="101500" checksum="0A5DF576A45FD35B" modified="2021-09-29" version="1">MAPKKGSRKQPDAAVEEAPEQQPATKAAKQDKPPVKEPAAASKANAGNDSSDDDSSDEDIDIDADTAAKLMELEHELQTSPTYEKHLEYITLLRSTPGLRTRLHDAHEALAAKFPLSEELWLAWVNDELAAVNGPDDVAGLLSLLRRAATRDYLAPGVWDLYLEVAHDLDPEVKEHTAEGADRYRALCEEALAAAGLHLAEGHKLWAKYRKYELAAEAKAAAAGQRVAAGKATDRVRALYQRQLAVPLADTAEVLEEYKAWEAGHGKPLPPHVAKAADKAREAAELRAGCEAAVGPEQPADVAKLGAFLSYIKMEQNAGDADRVQTVYERAVSAFPLTHSLWLQYGQYMETAAGGKLPKDKVNAVYERATRNCSWVGAVWERCLRSLDRTGAPPERLQEMYERALAAGLQSPEDYMVVVLARLDALRHTAVAAAEAAAAGGGAGSKKAAAAAAAALRSGFSSATELLMSHFPDYVDRSLRLPGYWAACEEHVLGDVPAAREVWEGAIKGGMGRFAEVWEAYVAMERSARRIKEARALYKRCYSRTFEEDGQLRLSHAWLRFEREEGSADDYLAALLKVEPILEESAAAAAAAADQAAAAAAKKAKVLSKEEMKAMRQAKDPNFDPEKATDKKEKKKGSKSGKRVRSEDEGEGALTSGDGEEAPPASTKRVRIHEPEAAPAAGPSSAPAVEAKAEDGDAEMGEGAHEHGGGEEAHDGGEGHAEEGGGAGQGPGGAHPRPHYTDKQTVFIKGLRPAVKDEQVDEFLKKSVPDGIKDVRIIRDQATGQARGFAYVECSSREALDKLVALNSTPFQGVSLFIAESKPPGHGGPGGRGGRGGRFGGRFGGPPGQGGYGGRGRGGYGRMDADGDAEMADADGHGGRGGRGRGGGGRHAGLGHPGGRGHMRTHLQIAPGTGPAPTTLVPRSVQLGGSAQQQGQAGEGKAMTNDDFRRMLLGGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4D5</accession>
    <name>A0A836B4D5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">SBP-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_007819</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4D5"/>
    <dbReference type="OrthoDB" id="514967at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd14733">
        <property type="entry name" value="BACK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1100.10">
        <property type="entry name" value="Transcription factor, SBP-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044817">
        <property type="entry name" value="SBP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004333">
        <property type="entry name" value="SBP_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036893">
        <property type="entry name" value="SBP_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31251">
        <property type="entry name" value="SQUAMOSA PROMOTER-BINDING-LIKE PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31251:SF169">
        <property type="entry name" value="SQUAMOSA PROMOTER-BINDING-LIKE PROTEIN 8"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03110">
        <property type="entry name" value="SBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103612">
        <property type="entry name" value="SBT domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51141">
        <property type="entry name" value="ZF_SBP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="BTB" evidence="6">
        <location>
            <begin position="39"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="domain" description="SBP-type" evidence="7">
        <location>
            <begin position="912"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="268"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="589"/>
            <end position="618"/>
        </location>
    </feature>
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            <begin position="631"/>
            <end position="716"/>
        </location>
    </feature>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="844"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="979"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1032"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="273"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="344"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="364"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="389"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="418"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="474"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="642"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="679"/>
            <end position="690"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="742"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="769"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="871"/>
            <end position="905"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="979"/>
            <end position="990"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="991"/>
            <end position="1001"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2447068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1063" mass="105704" checksum="D316B1D2FBEA7AFC" modified="2021-09-29" version="1">MSLPPDPEGCGAGAFIYRDTSARGLYAGLAPHFNDRRLSDICILRPDGKTVYAHQVVLAACSRKFSSVFGQGEATGKELPIQGVDSAALELVISSFYHGECRLTPTTVVPVYDVCLKLEVPGLTTACEQYLQRSMSADTCCIYLEAALGVLLEHTVKSCLTYAKGRFEEVAASPSFLSLSTKTVRLLLTQVRNSGSGITDISLARALARWAVTKPEHLSECESIFKELNVTTTALLQLLQSAEFVHALQSKPGVAAAGGAGVGGVGGGGSVAGAGNQQQQHPLPSPHHQQPPQAAAAAAGDATPASQQQQQGGAGPWRDGRETFGSVREASSREGGAVSSGLPALGGIGNGRTGGPNGSPAQNASSQQAPGGPAGATAGPPHGGPPQQPRSSPLLASSGAGKTGERGPHGDYGGDGPGARPASAAGAQYGTGSGGSGRGPSSQQAAPQQGSRPGSGRSPPPPFGRQSQPEHLAGAGGSSGLAVGGSDGPFQRRSLPPELLSGTADDDRQQAYARRYGTIAGGSPALRSLLGPGRGGGNDRAAPDSEIAAAAARGAGGGGGDGGGERDNLVALPLPMLELAGLTVQLTPSGTLAATGGPLGSKQVPLSVSSGSGRSGPLMVLLPAGVVRRLQQASSGPVAFESGGGGGSGRSGAVGSGGRPDDGSPPLPPGLLQPQQQHQQRDPGTDRPDRYGGPGVSPHAAAPLGRGSAGLGPFQRSSLDMLSSVAASAEEQAGFVDVPGLPRIGPAGARPASASGLAAGPRSASLGAGALGLSGGRSGRQVDLGGLGSLAQHMVSDSGGVPGRWSVPGIGPGAGGSTLLSLGGSLSGPGDLLSADAGSLNGGGGPLLGGISKRRRPSPEDFDPDHEEPGLGLGGAGGGGGRGGGGGLTPPAAGGGGGGRGRGGGGYSSKGPLLCHVDDCNVDLSSLKEYHQRFRICDFHLKAEVVLREGIPQRFCQQCGRFHLLSEFDGTKRSCRARLQRHNARRRKRPDQKGDGDDVPRRRPVYQTMPQHVSAGVVAGNMALAAAAAAAGMPGPHAGGGGGAGSSSMHIPGLPTSSGAAVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4F6</accession>
    <name>A0A836B4F6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_007861</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447113.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4F6"/>
    <dbReference type="OrthoDB" id="544410at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="19"/>
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        </location>
    </feature>
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        <location>
            <begin position="420"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="487"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="683"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="776"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        </location>
    </feature>
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        <location>
            <begin position="872"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
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        </location>
    </feature>
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            <begin position="242"/>
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        </location>
    </feature>
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        <location>
            <begin position="309"/>
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        </location>
    </feature>
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            <begin position="487"/>
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        </location>
    </feature>
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        </location>
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        <location>
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        </location>
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            <begin position="718"/>
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        </location>
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            <begin position="1195"/>
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            <begin position="1261"/>
            <end position="1270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
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    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2447113.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1270" mass="128241" checksum="DDA3E172C8E5C9CC" modified="2021-09-29" version="1">MANVPIVAASAAALTASLAGLAGLAQSIAGRREAGARARPGLRAPAAAAEDFEDDNVNLAESASVWLARRGSSQVLEPPSSSYGELELLADGEFVYFRKDTEVLTTIPHCKVLQLQPLQLAKGRSDAVPTAPLEPNSVWLVLRKKQEVVFMLLGSDHQRHVLEADPQSPLGVTLGGGAVKRRGRWTITPQGLASLAWPEHLLPLQVLTVQLVDARAVGSVKAAMARKLNELANILDGEAHHRAMAETRSQQLELELRRVKDEVASQVAELRAQLDAAVRGRHVAEREVASLQGQKADEAVRAKMAQARAAQAEFDAQQAAATVKGLQQQIQGMLAGHAEELRTLQNELQIAREANDGLKRAMGEQVMALQGALELRDARILELEEENERMDTVLQVIQAQLGQGGGSAVEGLSAAVEQARAAPEAGDSRGAAAQGGVGPSTCEGSEPSTCEPSKPEEEAQPEQPPLWKALLDSTGDISLTALKESLEVSRRNNPEEPRHANPPGSSDAAPEPGTQPASVEERAALESTEPSTGPTVPEPAAATNDRADAQADGSEPAGPRAWPFTLSPDRSFSLTDGGSDLPSGSAIQAAASASSSSSPTRHLQRQHSAAELEFGGAAVVTLDSLRRRMRALAAEYDRCAVLSQSLRESLPWRTADAAAAAANGGAGVLAAAAAAASGAGLEPVAEAAVEAPSTDSGRSRSSAGGVGSRRSAAREEVTSPTLAASSGRASWQASETPQELLEDGSGRKRPRQSFGSRLEGVMSGGGAGALAAASLSMEAAARPGRSSAAAVPQREGGTNGVAASTPPALGVGTVAPGVRATGSNVQRITQKLLAAGAGGSASAGEPNMNSIAAPRGPRLGSHALLVTDSLTSSTATLAGSPHSRSGAGGGDTDRSASASVSVSAMQQLATPFASASAPPAPGQALVPLRASSRSGSGSGAAGQEPGAEADATASPPGFTVHYTPWSASVSEEAQMPVPVGSEGSDDGREAEGATSSVRCNLSSSLGAGPTSRRGSASSSGSQQGSPGPESDSLSPLPADEPSGLRGQADAAVPPTDGPGGGPLKPAFANGPGSGGIGRFVPELKLEGTRADTGMYESIDGMCCLGSTRAFPTARNAAGALTARQVSHSRQASFGAHAAFAVAHDQLTPPVLSPAGAAAGPSTAAAAEADTFARTPLGEDAQSRGAAGAGAGGGAAAATAGTTPKGASTPPSGAALDDDAMHCDDQEPSPPPPGGMLLGTLEQLRGGGGPGTTGKRAALAALEEDDEEEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4H5</accession>
    <name>A0A836B4H5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007779</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000022">
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            <begin position="1"/>
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            <begin position="321"/>
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        <location>
            <begin position="440"/>
            <end position="454"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG2447456.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="558" mass="54936" checksum="F2BD7BFF77E7CBAB" modified="2021-09-29" version="1">MGDAFSRRREEDEAAELSQDVARKAVESPPAKASVASADGVCTPQVRLSGVREPTSGAAAGTEAAGPGSRAMHMQPPEEGRTQERPVRLPPTFTISNANSAAPGILSSHGVQLASPPAAQTLSMDAHGPTPVTPPPPHPSSTTTAARTVDPADELMAAAPVSHAEGAAPGINTAAAAAGGGPHVVRNLEAALLTAVATATADAAATDGRIRGAAAAAHAAAAELGEPGPGPHELLSGEGQQQQQQQQQQQPHGTHGGSVSPGKGAHGSRGALPARSAVTAVAAAASHTSRAAASTGGKEAVPRQHSTSTKRVGGSNASAEAAPAAATAAPGAQQQQQQQQQAGTGRIKRMSSNDHHHHTTTTTTTAASTITAAASRHDAEARGALSPADPAAVTAAPLPALSVPDADEAAAVAVQGPLPPPPAPPAHHVPHYLLPTAASMSRRSSQGLVSPLTDSGSHGHGSLTGTAAGTLLARDRSIHLPAAAAAAAAPAAQHHEGGGALPLPLPAVSPRSPTSPGSGLASRAVGRTTSLRRVSQPGGAVSDAAPARSTSRKESAVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4H9</accession>
    <name>A0A836B4H9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447173.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
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    <dbReference type="OrthoDB" id="2436248at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="541"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2447173.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="639" mass="65451" checksum="9EA1D84D6EB863C5" modified="2021-09-29" version="1">MEQADTNFISGLADEFGLGPAWELSAVTAFTGASAEIRAYIRGRPHNNKQVDLLNELMQASAAGLGVGNAAGAEGGRSGDAQSGGAGSAVGPLGVEVAAGAGGPDTSTEYIRRVLLKPLGAANVGGGGGDGGLLMMSAPAAAAVARLSDQPLGAKLPVLGRMAQSALASNSELGDYVVTAEADARLAADAYTLCMITTSALMGMSCNQFGGSETFTTVQMARLVDDPLSLAATSLGLHVRTDRNTTDRSGATGRQLRPDFLCWVDNVLLFKGEEKANASDLETAITELEARMATSWNPALLPGVSMPCMFAYAAAGSAVQFFAITSSGGGGAVQATAISDLLDTGTPLGRIKVVHHTLVIVRALAAYAPYAPKITMALGGRVGLGGAVEVFSEFVRKSVDLAQQHGTVMGYPGLADMYRTLSGVCCPNLVRLHSGSSSGAGGGGGSSSIRLQADGRTLVLHLEPVGLPLHGAPASEADLKQALRHVLTAVAALHAAGFVHRDIRWHNVIRLPAAASASTAGSQQPPPSAASSSSGNSSSPAGADTYVLIDLEHAAPADCDLDCRQPPHRLHTWPAADGLLDPATGRYTRQSDLCLVAAALMANLPFALSDAGRDLRQQLATRQVPSAEAALHHAWLCAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B5F0</accession>
    <name>A0A836B5F0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_007097</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000019">
        <property type="protein sequence ID" value="KAG2448070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216:SF65">
        <property type="entry name" value="PAXILLIN-LIKE PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24216">
        <property type="entry name" value="PAXILLIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="945"/>
            <end position="971"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="4">
        <location>
            <begin position="2878"/>
            <end position="2915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="74"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="283"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="535"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="784"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1127"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1182"/>
            <end position="1239"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1271"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1341"/>
            <end position="1372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1392"/>
            <end position="1413"/>
        </location>
    </feature>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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            <dbReference type="SAM" id="Phobius"/>
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    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
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    <sequence length="3051" mass="299504" checksum="9E5FE7688D53F322" modified="2021-09-29" version="1">MTNYSDASTASPASPVEPAGTRRRRATVPGSGRGHAERCARLRVKGPSVIVLLALQLLLGALLPPPCIVAAQGTRPPSPAPPRPAPPVPLLSGNTSSVVRSNGNTSSSNSTALRNTTSPSPRPSPSPRNATANTTGASDAQQFQQHNHVEFGCGLRAGLPSLITYCREATRRALQPEANHNPRLAIVSVVPDNGGATAPGAALGADSRVLGSAEAVLQPLLFDYAAGNLSTLSQLEANVSAGGALPDRYLSVPAGATGGPLQGPLLLFYRRDWWAHLLNHTSWGSSSSSSGGGGGSSSGGAATAAAAPPPPTWQSLLQVLEAAVNTNLEGGMLEDSGPDHVLCVDMMPGCKGWAVLAGIYASMVQTRGGWQGVFFNTSSSGASAGGLSPSVGGPAMAAALKLYARLARVNAPPYTPGGQSTSVDRAPVDPADLLVAGGAVDNDTGLPLCGMVNSLFAAGRCLFTIDWAAAGLQLTTGGAVGVSGNLGVGQLPGSIEAVDPAAGGTLQLCTPTSCPLAETTPPPFNTLLSSYQTAAEMGAQPPPPPSPMPPSVPPPSPPPPSPPPAYPPPPSPPSPPVPPSPPPPSPPPPPYPGNGAAVDMLNNRAPFLAETTHIFVPSPNQSAAEAARVNEVMRIVGFGVGLRYSLLQSLPVRSASAASNSSTASIAVSVAAVAAAAATTSSDAMCTAPQISLGVGGVGTATAAAAEAILDLATEDQDALVLAIQTALRHRNAASDIKLPYGNVYRSALDAAAVAAALTIKYDDSRAAADLAAMALMLRNANISSSSSSSSSSSSSSSSSSSSSTVNSSTRRSAIAAAGGDSAAATPGRDAAGAARKGEGAQPEGGAAFALVPVAQSGTDGGGGSSSNNNGSGSGNGVVVVDVGVVDPDPAVQQILVDLTTNFTDTLNLFPYPSILRLLHTFYLPAKPVEEALPAAPSSNNAMRLGLPIALTVGCTLIILAVLAAVAYWMVRSRRFRAKALKPPGPGPATTLVMTDVQNSTLLWELLPLGVMDVCLGIHHRIMRHAIADNFGYEVFTEGDAFAVSFWSPEDALSFCFQVQEELLMADWPEVLLQQEDGCEVWARRCIVGPAGHTGGAAVASLATAATTGLAAAVTNRGLRMLRTSGPQTQLALPPTDGAPAAAAAATPSAGGGAGGGGGGGAEGVYPGLAAVVAARWSTPAAAAVPSPPPPRPPMALPAPPLPQAAAAAAAPAAPPAPAPAPAPAPAPAPAPAPAPAPAKVTSRLGMLMARKDALDRFQRRHSAPLAAVATFGSGSSGGQPQAATGNGIVMAGGDAAPGASGGTSPSAARPPAGAGTGGSSPAGVEPATAAGLLTTAAGLQQGDGKAQGQVQGQGRRQGQALSGTPVRAPAPSEPLYKLQLLPVAHSMAAPGAGGGAGATAATAGRAPGEGRGADVSIRRLAQVREAEDGASSGGGIAGGSLSSATATASHAPAATAGCDGGGDGLADEGLIVLQPGLSAASLDGSGSSPEDSELSGRQHAATASPAAAATTAAATAAKARVAAAAAAVAAVAAAPVLPAAGMSAAAAAAGDGDGSLVGGDMESAIDDFLRGDADWRNEVTWEPTDQLIVAGGAKGSRKAIRLSSGNHRGAAATAAGGGGGGNRTSRAGGAPSSGDGARGGGAGGGSSRVGGGISPTLHQYLTRDRGRAGGGGGGYGAAASGGRRGGGGGGGGGGLVGPSMSDGVDQLPDLDAAVRTGSNRSVRGVVSDVLVDSGSVGVAPRRRSALGLPRLHLSAFYGGSGGGAAATPSPRAAAARRQFDTASQASGSPAPAGLITTTNAVAVAIDLDRSPSASPAAARSGSARRRRGGGGGGGGGGRAAATSGHGYGNQGHDIESQPGTGGGGGVLAKLGSLRLAVLRLGRNGSVTAGDGGGGGGGGAAQGPGETSGSASATPAGAASTPRRSATSPLATMDVSDVGEAAAAAAAAAGTVLEPPAAGGAIDTHHPTQLQSQSHPHSQDHTHGHGHGPGHGRGHGHSHGHGHGLPSHDLGHHSSSAAAAAAAAAAAAAATGAGAGASGPRLPILHDSHVVSAGPFLPSETTTVAAVPSRWGLKSMATTGPIGRRYLTGALPGAGGGGGAAAASAGGGGGGAGIFDKLWYDINTAAIAPPTAAVGGGGGLGHAGLAAVSGTTAAPSEGADTPVGTRRGSVSHWRAMAAAVSAATALTTAGRSVPPPAGGIGGAAGAGGASGTVTEEAVFASESGGGGALPKPPASRAPSASGGAAAAQAAAVAAAAAAAATAGPAAWVTVGAVLRRLWVVDPFGPLHLFRATAGAATLLDSHAAAIAEEGAASDCAVSATATALTAATAEGAVAGASALQLGSPRARDMLLAMRTGGDSAVSALMAGGSVVSVAAAAAAPPPYNNHANYHNNHNRHANRHQAPVLVFRGLRVRMGLNSGLEESERALPRHNVPVVRVPVSACASCCFLPLQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQHQYMVTQSGLGVQAVAYCGDFLATAKEVGDVAMGGMVLLSASAFAAYHSTQSRARKTGGGGGGGGGGGRLAPSELLLLHLGEHAFAKAAAPPPPPPQEQQRPSAPQLEGLDMLLQPPEPAAATAAPTAVAAALPTPPEPTVRSLYGALSPAMAPRLAVLPDLVRNTRVIAPGCLSAPAGAVVPVFCNVVGLEVLVAWERVMQQRAARELSAASTHATAASGGAGGGGRGGAGVSRRAAAAAAAAAGRTGGMSSDDGGGGGGGGSAPGSSGLSGGAGVVQAALRLLRTLGRAAVARHGGYVVASSWDGAHWVLVFPSPESAIMWGLDMLSSMLTADWPPGFTDHELTEEVLKDGVLVMRGLRLRIGVDCGRAMVRLVPRSGRLDYVGRPMNRAARIAAKAKAAWMLASDAVWQAAKAAVASAAVAHSLGSVSLKGVREDLHLWALRPRRCFPPSPAPSQPPAEPLLARPAAAPGSSAAAATSGKAERPSAGSLRSSSPQSRTAGSTRRAAMLAGAAAVPTAAVVAAVEDGGGI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B5F7</accession>
    <name>A0A836B5F7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_007275</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000020">
        <property type="protein sequence ID" value="KAG2447819.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="61409at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051144">
        <property type="entry name" value="Formin_homology_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011936">
        <property type="entry name" value="Myxo_disulph_rpt"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR02232">
        <property type="entry name" value="myxo_disulf_rpt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733:SF7">
        <property type="entry name" value="C2 TENSIN-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45733">
        <property type="entry name" value="FORMIN-J"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 6" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032302637" evidence="6">
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            <begin position="22"/>
            <end position="1731"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
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            <begin position="822"/>
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        </location>
    </feature>
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        <source>
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            <dbReference type="SAM" id="Phobius"/>
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        <source>
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    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1731" mass="167809" checksum="C2FE770A3E2EE98A" modified="2021-09-29" version="1">MLLVVVPALLLLLRLLLLARGGFVFLSSDDADDWGHCQGARCGSLYYSIIRKGLDLAPADASGILAVGQFLESSNATISLTGWVGNTTNITFARNASDVLSANLSSYKMLYIPSGYSDVDGGLDVSLNNALISIRSRIMDFVNNRGGSLVALMQRGLGSKALGFLPLAMNFTSMDVANVSVTQDMMTFSPSSNDVNLDHAFWHGYWTGPVDWNGLLVLSYVRAVLSAELCYNGRDDDGDGWADRDDPDCWRCGNGWTDPNEECDDGNVMNGDGCSSLCMSPAVLSPTPPPPPSPNPASPPAPPAPPPPPTSRPPLPPLPPILIPQIYIPPEYLAATATTAAIAAGPPATAVDDGRGNSSDSAARTGNNTATATTANGIATAAAATTTVAGTLTVAQEVSSVPEALASDPAALVALFPAAASITVTGRTVSMSFAVSTSMRRGDVAATTPSTAGATSSATTAGAVAGAAAGAASAAAAPPAAEAAAAAAAAAGGCSKAFLYSFRQELARRAAMSTQVFHNLTCTDIATGHEFDITGTDPGTLLQPAGAGAATADSTAVTAGSGGNGSSGSTGTSASTSSSRRLQQTSSSAAGGGGGAAAAAGLSCAAVASGDAVASLSMALTLKVPGDDANAMDAYKRQVMAALSAWEAEAAVATAAAASSQQQPAVGGGAAAAPLLPLVLQVCSPPEGRITTTSDLLVLMELALSPLGLSRLQSECGFGPDAGLVLTKALGGGGGGSGGSDSSSTSAVSCRVAAAQLPATAATLPDAAAAPAVSAGANGSNDDSAVAAGGATPDQVLPKPPSQATAAATPQQAASSSSAAGMLLPIIAAAAATGGVISSLAVVIGAVVLRRRRRRQREEEQEQQQRPHRNASAGPPGTQTPSGGGDGDRSLSGDDDAAPEPNKHLLPLVTLAATSPRAGGRGGGRRMTEVRGDGDGGGGNGGGGGGGLRGGDLPPAQLQQLRSSLSAMLPEAAAATAAAAAAAGGGGGDGGGGDGGRVPSSGRQPFCAAGGGGFGGFGVSGGVAAEPDDDEAEPPSMLMRALTSPPPPPAAGAGSSAGAAGTGRRRATGSTATATAITTPQYCAPYDSTAGASAGGGGDGGWGSGGGSANGCHTDQLPQHRPAGRLRTVSHNALFDPNDLEASTVGSGGGGGTTAAGGVFLSSTSSISSSIRPYSAAAPAAPAAPAAAGAAATSMARAASIRDRLVSMLAAVAAGVSTTAGGGTSSAAVAPEPSPTSAPQPLLSAAAANTAHHHHSTMMMAAGGRMRVSSSHPGSPRAAVRLPSPAAHSGSTTPARGSMRVAFAAEAITAAAAAAEAAASDAAIASAASSSRAGGAQRRLMLRPHTMSYDPGRTSDEYDKAMEAEVEAEDADRTHPHTYSRQQQQQQQTAAAASSPDGGTAGMTLTRSKSIGGTRWLAGRAAGAAAAAMAGQGAATADDADEDNRSGSSPGGANGANAITAGGSGSQSFRPRRATFTGRSATTSRIRNRPGAELENEGSAAAAAAVRNSGWGAAAASGTETKGDAPSLLGSSRRGPSFTAATAAAARAGSHVRAWPAADITSGDRAAVEGEGAAVTAAATEAAQPEPSRRRKGSGGVELGGGGAGSSAGGAGLWRSGALPAGHSDGGSSSGSSSGSSSGSSNSDGAATPHQQVLLAAASPSGGARLPPTAGDGGGSGDFVSNSGAGPGAAVATAAAAAAGGGVGRRLGSTGYTGTGSFRPSRFSTSVGTTG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B6I7</accession>
    <name>A0A836B6I7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_006088</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000016">
        <property type="protein sequence ID" value="KAG2448734.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B6I7"/>
    <dbReference type="OrthoDB" id="10475685at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2448734.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="139" mass="14666" checksum="15636527FD787563" modified="2021-09-29" version="1">MVSRTRAAEALGAATSDERGKLLFFLHKVSDEELSGWDIEGQDNDTILSFIREAYKHAQGGSLPAAAASAPGLGSAEGAGTASAANQGAVPLLGRGGDGGWFWLLFGHFAAVADRYPSPHRCTKRGGMQALQLMRQHQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B6L4</accession>
    <name>A0A836B6L4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Helicase C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_005794</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2449045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B6L4"/>
    <dbReference type="OrthoDB" id="196131at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47958">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DBP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase C-terminal" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="45"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2449045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="104" mass="10536" checksum="C27A670A267CC0E3" modified="2021-09-29" version="1">MPKTAEDYVHRIGRTGRAGATGTAYSFFTNGDARLARQVVEVMQEAGQQPPPELMQMVSFGGGGGGFRGRGGGGGGGGHRGYGGGGHGPSMTGANAIPVAPRRY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="22" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B8M3</accession>
    <name>A0A836B8M3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="20">Peptidase C1A papain C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="18" type="ORF">HYH02_004268</name>
    </gene>
    <organism evidence="18 19">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="18" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="18">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Acts as a defensive agent. Recognizes blood group fucosylated oligosaccharides including A, B, H and Lewis B-type antigens. Does not recognize Lewis A antigen and has low affinity for monovalent haptens.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotrimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the fucolectin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="18">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000009">
        <property type="protein sequence ID" value="KAG2450997.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="551758at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008234">
        <property type="term" value="F:cysteine-type peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042806">
        <property type="term" value="F:fucose binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010185">
        <property type="term" value="P:regulation of cellular defense response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001868">
        <property type="term" value="P:regulation of complement activation, lectin pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00054">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd00118">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd02248">
        <property type="entry name" value="Peptidase_C1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.120.260:FF:000163">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.350.10">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.250.10">
        <property type="entry name" value="SRCR-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051941">
        <property type="entry name" value="BG_Antigen-Binding_Lectin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Cas12f1-like_TNB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000152">
        <property type="entry name" value="EGF-type_Asp/Asn_hydroxyl_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018097">
        <property type="entry name" value="EGF_Ca-bd_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006585">
        <property type="entry name" value="FTP1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008979">
        <property type="entry name" value="Galactose-bd-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018392">
        <property type="entry name" value="LysM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036779">
        <property type="entry name" value="LysM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049883">
        <property type="entry name" value="NOTCH1_EGF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000169">
        <property type="entry name" value="Pept_cys_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000668">
        <property type="entry name" value="Peptidase_C1A_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039417">
        <property type="entry name" value="Peptidase_C1A_papain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001190">
        <property type="entry name" value="SRCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036772">
        <property type="entry name" value="SRCR-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45713:SF6">
        <property type="entry name" value="F5_8 TYPE C DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45713">
        <property type="entry name" value="FTP DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="Cas12f1-like_TNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07645">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01476">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00112">
        <property type="entry name" value="Peptidase_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00181">
        <property type="entry name" value="EGF"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00607">
        <property type="entry name" value="FTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00257">
        <property type="entry name" value="LysM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00645">
        <property type="entry name" value="Pept_C1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49785">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54106">
        <property type="entry name" value="LysM domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56487">
        <property type="entry name" value="SRCR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00010">
        <property type="entry name" value="ASX_HYDROXYL"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01187">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51782">
        <property type="entry name" value="LYSM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50287">
        <property type="entry name" value="SRCR_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00139">
        <property type="entry name" value="THIOL_PROTEASE_CYS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0106">Calcium</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="4 12" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-0430">Lectin</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="19" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
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<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
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                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">CCAP 11/173</strain>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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            <title>Comparative genomics of Chlamydomonas.</title>
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                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
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        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="2">CCAP 11/173</strain>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
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    <name>A0A835SBN2_9CHLO</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <dbReference type="NCBI Taxonomy" id="2026947"/>
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        </lineage>
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    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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    </feature>
    <evidence type="ECO:0000256" key="1">
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        <source>
            <dbReference type="EMBL" id="KAG2424327.1"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="146" mass="15232" checksum="84F6F38A836AD874" modified="2021-09-29" version="1">MRAQASAESGGPLEARCGGASAHAGGDPDACRGKEGALLFESACVQPIHKRVPVSVQMWAALQRALPAAAPTRSMSNGSGSGEGAHAGHLRLYVEDQGTGKRSNAFCVCLKTDRSGTYITRLPPMAVGRICIGWELQGSQLVMRVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SDR5</accession>
    <name>A0A835SDR5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the FAM221 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000116">
        <property type="protein sequence ID" value="KAG2425408.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SDR5"/>
    <dbReference type="OrthoDB" id="196393at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026755">
        <property type="entry name" value="Fam221a/b"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31214">
        <property type="entry name" value="PROTEIN FAM221A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31214:SF3">
        <property type="entry name" value="PROTEIN FAM221B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14753">
        <property type="entry name" value="FAM221"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00011026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2425408.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="195" mass="21989" checksum="264B8E1562060F8A" modified="2021-09-29" version="1">MIDAEEAAAQLAMQTGIYGVWRSAKGGDCTRIGPKARCFCDHPFADHFFVSPKSPYPICKSCNCRGFAFIPSRPEEIGEWWLPRRKGFNVHTWRAKCRCGHGHDEHDPHTRRCRCGCPAFTSNFACLACDLKWEDHETVFETARERLVAGRPVGEDFRPLADDPALRDMVFPEGHSADSADAYVPNRPTPAMRFS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SE60</accession>
    <name>A0A835SE60_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_014991</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the splicing factor SR family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000114">
        <property type="protein sequence ID" value="KAG2425617.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10266058at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12230">
        <property type="entry name" value="RRM1_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12231">
        <property type="entry name" value="RRM2_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000097">
        <property type="entry name" value="U2 snRNP auxiliary factor large subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006529">
        <property type="entry name" value="U2AF_lg"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01642">
        <property type="entry name" value="U2AF_lg"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="6" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 8" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="1643"/>
            <end position="1725"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="10">
        <location>
            <begin position="1760"/>
            <end position="1838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="43"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="197"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="246"/>
            <end position="811"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="861"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1378"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1491"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="55"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="263"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="281"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="295"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="317"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="342"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="365"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="438"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="450"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="500"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="532"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="572"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="614"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="638"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="649"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="664"/>
            <end position="689"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="692"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="733"/>
            <end position="758"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="773"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="881"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="901"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="913"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="946"/>
            <end position="961"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="977"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1113"/>
            <end position="1125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1149"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="1217"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="9">
        <location>
            <begin position="1509"/>
            <end position="1527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1546"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="1567"/>
            <end position="1577"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010269"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2425617.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2011" mass="211314" checksum="C4706953E6DC1CF2" modified="2021-09-29" version="1">MKWAPRHIGYPGYYDYYGTAAAAAGTDTSAAAVKDRPVQVVPLNASAKAGDSKSADGQAKQSAGSGSGQGQEQAVAAAAAGADDDTMALPPPSEPKPTASGAGGAEAQPPLPATAHQYPPEEELTDFQRKMLELMEKKKEEAERKRKGQQQTLHTLRGARLAIAAGAAGAAAAAAANTGGGSAAVAAAARLINSGDPLAAFSEEPPSKPDPKAKADTGAAGGTSKKHQIGGLNNLSLIINAPLASLTLPPKFDGPTPAELKYGRPRSRSRGRGGRYDSRSRSRSRGRYASRSRSRGSSSSRSRSPGWRGRSRSYSPRRGDGGFRGRGRGEFRGRGGWRGRGGRYDGGRGRGRGDWQGGEGGYNRGRSRSRSPSRSRSRSRSRGRSRSVSRSPIRRSRSPGPPRRSRSPGPPRRSRSPGPLRRSRSPGPPRREGGPPGREGSAGPRSRSASPRERRPCDDGYRPQGEELPRRRVGGGGDGDSDYECRGGDGGGRGFRGRGGRSGLWSGGRGGPGGRGGPPYDRNQNYDAEYEGGPGPGSGRGRGGGYFGRGRGGRGGGDGGWHSDDDRDYYEGPGGRGRGEYGGFRGGRGGRGGYGPGPGRDGGFRGRGRGPIDPGRDGGYERRYNDHDHDDDWRDDYGGGGRGGGRGRGGYDDYRGYREYDGYGPSGGRGRGRGGWYGEGRGGGGGSGGPLPDDRWRPDLSPDHEVLLTAERDSEREVGGRDAVRRGSASPEPGRELQHERAGKRSRDLSDGGRDRAVAADGSRGGEPPLQRSAAATPAAAPAAAAAAGPSAAAAAMEEEERLQEEERRLAEAAAKAAAAAAAAKAAAEKSAHDFITAFEDLDKLDIIDTSVALRPLSLGGAAAAAEDDGGPAGMWVEVKPSAPAAVPQPQAPQAQALAPTPAPAPSPPPAAGPSAALAPAAAAPEQRCRSPSPPDVDMEVEPAVEEPQPVAQPAQAQPQKPQDEPPPEPQRQQPHQRADHGPEEYRPRERDWDQEPQRGRNWSLERRHGPDWERGRERGCDLEFDHGPDVGWERGRERDWQRERELDRSRERDWDREREPDRRWEQESDRQQPGPERERGRAWDREAEPDRGQQREGLGRSPRRRASTPGSASGGEEGSRGAGGADERAVSGQDADGGDAEAMGTGSSKKHKKHKKKHKKEKEKDKDKKEKKEKRKKEKKERAAGAAVEDEERDRDGRDVADPTASPAADRYGSVDGERGRSPPPYYDDRYGHWLPVGRRQGPAATSTATMTADMIGDGTTETRNTIEVTAVASGSMTVAAGAAEEAEASTDRMDMGLPITTAAMAEVGDEAGPPFAVVVVITADGAVVMTITMIMATQLPAATEAGVADVGSSAFPEAVAAAVVLLAASMAVATTTATRRTERRGGSPSAGAMTTKMAPHHLPVGPSGACGMKNAGYGLSLVRMTTMARVGAHRRGATALAAVPCRRRLSGAAAGRFLAPALPKAIGAALHPPALGALAHSRRLNAGERQAVTVGGRGSSTGTITAARRRRRVVTPAHRNHRGRSYSRSPPRGGAAPGPGGPTGRRSPPRAQSRSRSRSPAARGTAGGTVGGGGASAAAAAQLLPEFKRGPRPDSPPDTRTREEIRAEIARATEIARAASQLAAGLMPAAPQQLQLTRHARRVYVGCLPVGMSEVALTQFFNQIMMASGATTQPGPPVMSCYMNVDKRFAFLELRCVEETSNAMAFDGIQCQGETLKVRRPHDYNPAAAKLLGPTEPSPKVNLALLGVINTLVEDGPNKIQVEGLPKCLTEEQVRQILQAFGPLKAFNLVLDRETGNSTGFGFCEYADPAVTDTAIQGLSALIIQGKPLIARRANTSAETSQTLQTLIQRQQQALVNSGAGANNGAPSPQARAALTAAATAVAVAAGAKAVVASPPAAAPSPSGSGPTVVRLSKMVTREELLDDGEYADLLEDITEEVGKYGKLVGVQIPRPGTSGVADPPGVGLVFLCYEDTAGAKRAQVALNGRQFGANLAEATFYDRARFDAQEFT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SF73</accession>
    <name>A0A835SF73_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014937</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000112">
        <property type="protein sequence ID" value="KAG2425874.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SF73"/>
    <dbReference type="OrthoDB" id="541059at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032347">
        <property type="entry name" value="DUF4864"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35716:SF6">
        <property type="entry name" value="DUF4864 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35716">
        <property type="entry name" value="OS05G0574700 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16156">
        <property type="entry name" value="DUF4864"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2425874.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="351" mass="37617" checksum="52EBCED4094E2971" modified="2021-09-29" version="1">MRLAANGRVSMRASTRPRPVCRSPTVRTTALYHNPGPKDNGKTKAAGAAVEKVLELVAAGDREALCDYFATSNLTDAPTLKLASGCEVVVFEDVMESMMLREPSRHFLDSYAIRHLILNAPASKQTLSGLMLGPNKYVQRMSVTAPSGESCILTFTMTATVALPELGTAAGAVAAASVPANQAVTAPVPPSEPVWRLSSVRGEPQFGAASTQPVGPSPELSPEQIVEAQLAALQRKDVSAAFQFLSPGSQKIIGDERQFAENMSRHRRYGGLLGHIAATSVRRCMARPSTYMEIVSVTSASGIRFVFCYILGHENGMWSIDFVKVIDDPRLVAAVESSCAAQRKARPADEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SG86</accession>
    <name>A0A835SG86_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Carboxypeptidase</fullName>
            <ecNumber evidence="8">3.4.16.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_014773</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the peptidase S10 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.4.16.-" evidence="8"/>
    <dbReference type="EMBL" id="JAEHOD010000106">
        <property type="protein sequence ID" value="KAG2426414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SG86"/>
    <dbReference type="OrthoDB" id="443318at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004185">
        <property type="term" value="F:serine-type carboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019748">
        <property type="term" value="P:secondary metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.12670:FF:000002">
        <property type="entry name" value="Carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1820:FF:000143">
        <property type="entry name" value="Carboxypeptidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.12670">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001563">
        <property type="entry name" value="Peptidase_S10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033124">
        <property type="entry name" value="Ser_caboxypep_his_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018202">
        <property type="entry name" value="Ser_caboxypep_ser_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802:SF254">
        <property type="entry name" value="SERINE CARBOXYPEPTIDASE-LIKE 20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11802">
        <property type="entry name" value="SERINE PROTEASE FAMILY S10 SERINE CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00450">
        <property type="entry name" value="Peptidase_S10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00724">
        <property type="entry name" value="CRBOXYPTASEC"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00560">
        <property type="entry name" value="CARBOXYPEPT_SER_HIS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00131">
        <property type="entry name" value="CARBOXYPEPT_SER_SER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2 8" id="KW-0121">Carboxypeptidase</keyword>
    <keyword evidence="6" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="7" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="5 8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 8" id="KW-0645">Protease</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="8">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033099421" description="Carboxypeptidase" evidence="8">
        <location>
            <begin position="27"/>
            <end position="540"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009431"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022645"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU361156"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2426414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="540" mass="58373" checksum="D482D049F2ABF8A1" modified="2021-09-29" version="1">MLHRLRLPALALAFSVLGLLCCGSNGARLPARGDISKKHSGKSSDNGQLTPEAAADAILALPGFTNQQLPSRHFSGYVTVDESRGRRLFYYFVESERDPANDPVVLWLNGGPGCSSFDGFVYEQGPFLYDLIPGPGGRGAQAVSLRKNPYAWSKVANMIFLDSPAGVGLSYSEHASDYVVDDGRTAADADAFLRGWFARFPQYQSNDFYVSGESYAGIYVPNLVRQVLVGNEAGEEPVINIVGYLVGNGCTDERYDGNAHPLYAATKSLLPWAQFRQLEAECGGEYWNRTSGSTCDKLWGRLSSNLAALNIYDTLQDCFHGDDDASTASASASGRTPDALLGGAVATQEQLAAAGLLGVWPLPGGAVRPGPVMNWAHVQKRLGRLGLTPPCTDSRAADMWLNDPAVRQALHAQPLSAIGPWTLCSDKISYTRNHGSMIPIHVNNTKTHGLRALIYSGDHDMAVPHTGSEAWTSELGYPVKSPWQPWFVADRQVAGYYVEYGHGLTYATVKGAGHMVPETNPRDSLALFQRFLADTPLSGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SME9</accession>
    <name>A0A835SME9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_013957</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000083">
        <property type="protein sequence ID" value="KAG2429699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SME9"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08529">
        <property type="entry name" value="STKc_FA2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001226">
        <property type="entry name" value="NimA-related protein kinase 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000097">
        <property type="entry name" value="Probable serine/threonine-protein kinase nek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF7">
        <property type="entry name" value="NIMA-RELATED KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="9"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="290"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="393"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="410"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="38"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2429699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="525" mass="58101" checksum="4B9BF7BE406502C0" modified="2021-09-29" version="1">MARSTYDDFIIKEKIGSGSYGVVFKVVRKVDKHVYAMKEIDLQGMSRKEQEECIRETRVLSSLDSDYIIRYYDSFLEKGKLYIITEYAANGNLHDYIKKQKSRLPEDLIWKLYIQILLGLNHMHSKKILHRDIKTLNVFLDEDLNVKLGDMGVAKILSTNTVFAKTIVGTPYYLSPELCEDKPYNEKSDVWALGVVLYECCTQRHPFDADNQGALILKILRGKFPPVSGYSPDICDLIKRCLTQNANRRPNTYKLLLLPSIRQKGEELGISLPDQASLAIMADKNMANAGAAGKASRPKTPQGDMNAPPEVAGSSVSDDKAFVFGSTIRAEGAGARPVDVSVSAVEATPGEGAALGAAPVPVQTAWAVDDAKPKVNRPPAWGLAQQMEDLAVDDGEDEDEGKNPYLGVGGDDDDDDDGEGEDDDDYDENGEYGDEPGEGEPGWTPDPTRIAHMKSAMMIQRAACLDLVGEKAFNELYALLKSNQVDEASMTDLSRLVFKIIPYDKSEVIQMMYKLLYLESQLEGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SPI3</accession>
    <name>A0A835SPI3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014062</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000086">
        <property type="protein sequence ID" value="KAG2429406.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SPI3"/>
    <dbReference type="OrthoDB" id="551874at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="33"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="257"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="75"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="95"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="159"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="262"/>
            <end position="272"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2429406.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="317" mass="30996" checksum="4A5DBBCADEC84571" modified="2021-09-29" version="1">MQGQDSDPASFFFATGPEGFSLAAADDAWNEGGYQAVEGDSEDDVMRRLRPSFADPRALAGPGAPSSSLRDDGRGATAAGGAYAEGAAAATAASRGGGGGGGLGGSWGGDEAGRRRLGGRWGAGGKGHAEPGGGAGTVGPRAHGGGGGDDVSSLPWRSRSHDDARRHAGPTDRMPYYGGGDVLPRDQLPPYGYVVGTADVPLPYSSGYSRLHGGDEAVGATAGGAADTRGGGGSGTGSGAAGVFGAATAQAARAAAADRGESSGGGAAGGGVAVPTTRSWPAHGERPEEGFVSGGRHVLYWWAGGWVGGWVGGWVGT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SPJ3</accession>
    <name>A0A835SPJ3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014590</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000101">
        <property type="protein sequence ID" value="KAG2427368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SPJ3"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="18"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2427368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="83" mass="8247" checksum="FCC4D0BC98210A18" modified="2021-09-29" version="1">MEDVGLVLDMDAIMLAPAGQGNQGLGQQAHRQQQQQKPSGGGAAPTEARPLNSVDLLGTQALEALAAADIDGAAHSAGGGDES</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SPJ5</accession>
    <name>A0A835SPJ5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">USP domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_015220</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase C19 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000127">
        <property type="protein sequence ID" value="KAG2424235.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552341at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016579">
        <property type="term" value="P:protein deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02257">
        <property type="entry name" value="Peptidase_C19"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.70.10">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038765">
        <property type="entry name" value="Papain-like_cys_pep_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050164">
        <property type="entry name" value="Peptidase_C19"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001394">
        <property type="entry name" value="Peptidase_C19_UCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028889">
        <property type="entry name" value="USP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018200">
        <property type="entry name" value="USP_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24006">
        <property type="entry name" value="UBIQUITIN CARBOXYL-TERMINAL HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00443">
        <property type="entry name" value="UCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54001">
        <property type="entry name" value="Cysteine proteinases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00973">
        <property type="entry name" value="USP_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50235">
        <property type="entry name" value="USP_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="USP" evidence="3">
        <location>
            <begin position="299"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="608"/>
            <end position="639"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="657"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="714"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="766"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="875"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1061"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="45"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="171"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="657"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="786"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1103"/>
            <end position="1115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1123"/>
            <end position="1136"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2424235.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2230" mass="231534" checksum="24B0596E63AD7770" modified="2021-09-29" version="1">MQRAKLNAYDFGEDGSEPEKILPVLAEYSAWLELLRLLPTDAQNSAPAKAAEAEAQAKAAEAAASSSQPSAAASTTLAVPPQDAPLKWQQAASTGGGALWRGRSVGAASAIVAQQPPGVAWCHSLLGTSPATALQSSSQAEGGSKRYGAESDSDKVTRAATISCAEPRPPASTTSAPQWQQPREGPTWCRAAHRSGQLSASSAAPLLQCTLPAVHKSGANQGYSAVSPSGKAQAASPRGTFLDVLLRANRSPPAPLRGGLQAGSMGLDVAAATHRDVHGSPSAASAASLSSAARPAGVVGLPNPSGTACSLNSILQALNAVPELVAAFCRPAPGLWSKEARVAPLISKLMQAMQSGQRVDATTVSDLWSLVTARMEADAAKQQDVHEVFTHLAGALQEEGAERSIMEVIFGFTMQSTLSCQCCGFASHSIGYHITVQVPTDGDHAQISEVMEAAFKEEKNIGARCPRPETLNNVPCGEKACVSKQLQPAEAPPVLAVMLQRVAHSSGSTSSTKTHTVVELGTEGLTMRYNRLLESGGSCPSKQQYKLFATINHRGRNTYEGHYYADVHSSAYDGKWYRCSDEAVAEVAPPSASDCAYMLLYRRVDARPPQGASPGGSAGQARSLLLGPSCSRSSSGQRTAADGRGLLMSTCNFSACSPPASTSPLLQTRSDQNSERRQRGPMAALATARAPAVVTATNCNPVSLPGQCNGCSGGSGGGTSAVPPTSRDAPPPQSRRSTRLGTGGVRGVQATGTAPVAAATSGVLPAANDAPLLPSRRSTRPGAGGAQTTDKAPAAAVAVATSSDTGASGGVGTGNSTVPPTARAIPPPQSRRSTRLGPGRRGVQATGAVPAAAVATSSGGGAGICAGTGTSSVVPTANDAPPPPSCPSTRLGGGSGGEVSSTSVTAAATAAAGKSGIIAAAAATPSAASGRGRSFSAEADDARIIQEEASQLWRQASCREKPAGPSVRSDEASAGVATGMKEDAIPLVIGVVAAGSYDQPCARSPPPVVSTTLPSPHKAPWQKESSSAIIEHPAAASHQRCVPICGGCGGPPLTAAEPEGMEAGAAADARDAEELAVEGQTGASTSAAGHIDEGVSAGHRPGRWSSGSRGSASSSVVPLATTAGRSTLEAATTGVQQEEAGTAGGRRQSSGCSGNGSPPPHSQQPAAGRRRAAEVHGATARAEDGALVEQYSSKQGAAVAAASSNGAVVIASKAEPAAAAVERAGADAAAAEMVVAADRLQRCVAPAGSGGSGMAGAEAVEMNNQRCKVPAGGSSNGGQIMAHREWYMHAGEEMIKTWAEAMQRLGDHTSQTLLGLNVLILGLVLLRQSKTGASQPWKRGSTLATLKKQLQQEASAQRLNLDACLTWAWIGAAGYAGSPLNSESFKVAMTTVQNCLEVESNAIGEGRSNRVFKVAGLDGVVMRTRKAKPPAQLLDAIYQQGPAIFNHLLVAGMPQPNLQSTAVGVIVKGLWPQVNGRVVDPTNRDEVLSLAQSARNVTIVMVLEKLVPLDTAAAHLGAIARRRKEGVCYLSVLMSMLNSVLRSASGLLLQGYWAKVDVKANNCAARPQHSLDQQAMVSMPVSWQPDDSHQQLAPTLKASGAACTAGFRTFELDTDSIDMCEYGVKDSYVKGNVDEECLQRYKPAARMLSSSMAQIEVAGFKTAVMVEQLLAMANGDDTSAGSTAWENAWAREENKNKVMHIGRPAAWRVTGDASGVLGVLYPEEMPSAVLAQVLAALMHPLPSRRKYLPDLLPRLSCTTDALNARTLRLPNAARDQSSEGVFANLCSGPQTDVLEELCGEVLQNWAGDPFVAATLTPLLELLYQAAYHTWPAGPINDFMQRLLKLAVLCDAIHVKMQDGKRRPNLLMLQRKTCHHDRTLTHLLAATGNTEAYLNVLNTLYTAGFVYKVASIMNAIDENQDTDVMLAGVHGQLEPILAKFYFTLEKLRELDGNVAQGWLLWVSSTSELGSFLTILCSLHNGHNKLRRWAYIPPKLQLPQGIKELSPLTSALDGVQQKVLQKLADYNVPAAAVLQATPRAPAPQHVEPDQLLLQVIRAALQVPRACANKTTLQAFVTQQVHDMLKAKTAPELGGDTAFHMLAAMAGLLPEVHGDVKSLYGPDIASACLVEKNKDGHTPVEVLLDCHPVVMSKAGLAGLASLAALPDTANAPKGLCKLVPTLRSFVEDLVREVAVDTANGTGQLEGARAVIAACGEQLQELDSWASQMQISVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SQK8</accession>
    <name>A0A835SQK8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013366</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000073">
        <property type="protein sequence ID" value="KAG2431379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SQK8"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="41"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="68"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2431379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="104" mass="10883" checksum="1A3E0BD7CA9EBE1F" modified="2021-09-29" version="1">MIFPKLLEDSSNTVASESEDGEADVLGKVAYLTLATACSMFLNSLSFGCALAAAGVTLVAFAQQPLPWAGAFAGTFLGPLIGCTYLLVRLGQATFKQAARNYVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835ST03</accession>
    <name>A0A835ST03_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Isocitrate dehydrogenase [NADP]</fullName>
            <ecNumber evidence="10">1.1.1.42</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HYH02_006656</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>D-threo-isocitrate + NADP(+) = 2-oxoglutarate + CO2 + NADPH</text>
            <dbReference type="Rhea" id="RHEA:19629"/>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:16810"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="EC" id="1.1.1.42"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="10 13">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
        <cofactor evidence="10 13">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
        <text evidence="10 13">Binds 1 Mg(2+) or Mn(2+) ion per subunit.</text>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the isocitrate and isopropylmalate dehydrogenases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.1.1.42" evidence="10"/>
    <dbReference type="EMBL" id="JAEHOD010000066">
        <property type="protein sequence ID" value="KAG2432669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835ST03"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004450">
        <property type="term" value="F:isocitrate dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051287">
        <property type="term" value="F:NAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006097">
        <property type="term" value="P:glyoxylate cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006102">
        <property type="term" value="P:isocitrate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006739">
        <property type="term" value="P:NADP+ metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006099">
        <property type="term" value="P:tricarboxylic acid cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.718.10:FF:000002">
        <property type="entry name" value="Isocitrate dehydrogenase [NADP]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.718.10">
        <property type="entry name" value="Isopropylmalate Dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019818">
        <property type="entry name" value="IsoCit/isopropylmalate_DH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004790">
        <property type="entry name" value="Isocitrate_DH_NADP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024084">
        <property type="entry name" value="IsoPropMal-DH-like_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00127">
        <property type="entry name" value="nadp_idh_euk"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF006156">
        <property type="entry name" value="PRK08299.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822:SF21">
        <property type="entry name" value="ISOCITRATE DEHYDROGENASE [NADP], MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11822">
        <property type="entry name" value="NADP-SPECIFIC ISOCITRATE DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00180">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000108">
        <property type="entry name" value="IDH_NADP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01329">
        <property type="entry name" value="Iso_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53659">
        <property type="entry name" value="Isocitrate/Isopropylmalate dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00470">
        <property type="entry name" value="IDH_IMDH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0329">Glyoxylate bypass</keyword>
    <keyword evidence="6 10 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="9 10 13" id="KW-0464">Manganese</keyword>
    <keyword evidence="5 10 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 10 14" id="KW-0521">NADP</keyword>
    <keyword evidence="8 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0816">Tricarboxylic acid cycle</keyword>
    <feature type="domain" description="Isopropylmalate dehydrogenase-like" evidence="15">
        <location>
            <begin position="12"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="78"/>
            <end position="80"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="80"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="85"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <begin position="97"/>
            <end position="103"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="112"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="12">
        <location>
            <position position="135"/>
        </location>
        <ligand>
            <name>D-threo-isocitrate</name>
            <dbReference type="ChEBI" id="CHEBI:15562"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="254"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="262"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="13">
        <location>
            <position position="277"/>
        </location>
        <ligand>
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <begin position="312"/>
            <end position="317"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="14">
        <location>
            <position position="330"/>
        </location>
        <ligand>
            <name>NADP(+)</name>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
        </ligand>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="11">
        <location>
            <position position="142"/>
        </location>
    </feature>
    <feature type="site" description="Critical for catalysis" evidence="11">
        <location>
            <position position="214"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PIRNR" id="PIRNR000108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="PIRSR" id="PIRSR000108-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="SMART" id="SM01329"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG2432669.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="415" mass="46339" checksum="6B935315E54B44FE" modified="2021-09-29" version="1">MATAGKIHVANPVVDLDGDEMTRVIWQQIKDKLILPYLDLKIVYFDLGLPNRDKTNDKVTEEAAYAIKEYNVGIKCATITPDEARVKEFGLKKMWKSPNGTIRNILNGTVFREPIVISNIPRLVPGWTKPIVVGRHAFGDQYKATDFVVDGPGKLEMTFTPASGGPPRKFEVYSFEGPGVAMGMYNTEESIRGFASSCFEYALQKRWPLYLSTKNTILKAYDGRFLQIFAETYESQYKKVYEEAGIWYEHRLIDDMVAQALKSSGGFVWACKNYDGDVQSDIVAQGYGSLGLMTSVLVTPDGKTVEAEAAHGTVTRHWREYQKGKPTSTNPVASIFAWTRGLAHRGKLDNNAELIQWTHDLEAAVVETIEQGHMTKDLAICVHGTTKVTPDQYLNTEPFMDAIAATFAKKRGGKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835ST23</accession>
    <name>A0A835ST23_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Thiol methyltransferase 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_006683</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000066">
        <property type="protein sequence ID" value="KAG2432699.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835ST23"/>
    <dbReference type="OrthoDB" id="276151at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008854">
        <property type="entry name" value="TPMT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32183:SF11">
        <property type="entry name" value="THIOL METHYLTRANSFERASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05724">
        <property type="entry name" value="TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51585">
        <property type="entry name" value="SAM_MT_TPMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2432699.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="239" mass="25434" checksum="272ED98F6C8CD9C5" modified="2021-09-29" version="1">MVASATEGVKISAAGLPMVAPPGGEPEIYSDRWELLWSAGVGKGQRWDCAAPSPSLVDLLKSGKVDAKGKRVFVPGCGRGYDLPVFRSAGASQVVGLELAPSAVREAQAHLQELGLPEADAAAIEMLSGDFFRWSSPQGPFDLGFDYTFGCAMHPSMRADWASTWAKSIKPGGTLVTLVFPINPDADPNVGPPFPISPALFRTLLEPAGFEVVSEAPVPAELSHPPRVGKEVLMVWRRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SUS7</accession>
    <name>A0A835SUS7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">signal-recognition-particle GTPase</fullName>
            <ecNumber evidence="8">3.6.5.4</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_012516</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>GTP + H2O = GDP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19669"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:37565"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58189"/>
            <dbReference type="EC" id="3.6.5.4"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="9">
            <dbReference type="Rhea" id="RHEA:19670"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the GTP-binding SRP family. SRP54 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.5.4" evidence="8"/>
    <dbReference type="EMBL" id="JAEHOD010000061">
        <property type="protein sequence ID" value="KAG2433584.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SUS7"/>
    <dbReference type="OrthoDB" id="1727884at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005786">
        <property type="term" value="C:signal recognition particle, endoplasmic reticulum targeting"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008312">
        <property type="term" value="F:7S RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006614">
        <property type="term" value="P:SRP-dependent cotranslational protein targeting to membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd18539">
        <property type="entry name" value="SRP_G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000022">
        <property type="entry name" value="Signal recognition particle 54 kDa subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.140">
        <property type="entry name" value="Signal recognition particle SRP54, nucleotide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.260.30">
        <property type="entry name" value="Signal recognition particle, SRP54 subunit, M-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00306">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036891">
        <property type="entry name" value="Signal_recog_part_SRP54_M_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013822">
        <property type="entry name" value="Signal_recog_particl_SRP54_hlx"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004125">
        <property type="entry name" value="Signal_recog_particle_SRP54_M"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004780">
        <property type="entry name" value="SRP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022941">
        <property type="entry name" value="SRP54"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000897">
        <property type="entry name" value="SRP54_GTPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042101">
        <property type="entry name" value="SRP54_N_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00959">
        <property type="entry name" value="ffh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE 54K PROTEIN SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11564:SF5">
        <property type="entry name" value="SIGNAL RECOGNITION PARTICLE SUBUNIT SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00448">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02881">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02978">
        <property type="entry name" value="SRP_SPB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00962">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00963">
        <property type="entry name" value="SRP54_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47446">
        <property type="entry name" value="Signal peptide-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00300">
        <property type="entry name" value="SRP54"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="4" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6" id="KW-0733">Signal recognition particle</keyword>
    <feature type="domain" description="SRP54-type proteins GTP-binding" evidence="11">
        <location>
            <begin position="350"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="43"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="539"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="59"/>
            <end position="69"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005450"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023135"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00035672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS00300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2433584.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="566" mass="61367" checksum="DE2AC723D99CDC8C" modified="2021-09-29" version="1">MQTALRGRSAALRGGWNRNDAVAPVASVHLRGQYAPFSGASQAASAPVPACGAQPLSSGRRPQPLQRTPLQRRRGGLVIRSAMFDSLSRSIEKAQRLIGKSGTLTAENMKEPLKEVRRALLEADVSLPVVRRFIKKVEERALGTKVLEGVTPDVQFIKTVSNELIELMGGGIGAKDLEPGFPQIILMAGLQGVGKTTAAGKLALYLKKAKKSCLLVATDVYRPAAIDQLVKLGAAIDVPVFEMGTDVSPVEIAKRGVEEARRLGVDAVIIDTAGRLQVDEEMMGELRDVKAAVRPSDTLLVVDAMTGQEAANLVRSFNEAVDISGAILTKMDGDSRGGAALSVREVSGKPIKFVGVGEKMEALEPFYPERMASRILGMGDVLTLYEKAEAAIKEEDAQKTMERLMEEKFDFNDFLNQWKAMNNMGGLQMLKMMPGFNKITEKQLYEAEKQFGVYEAIIGAMDEEERSNPEVLIKNLARRRRVAQDSGKSEAEVTKLMAAYTSMKAQVGGMSKLLKLQKAGADPQKANKLLQELVASAGKKVAPGKVRRKKEKEPISKARGFGSSSK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SUU5</accession>
    <name>A0A835SUU5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_013175</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000070">
        <property type="protein sequence ID" value="KAG2431957.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SUU5"/>
    <dbReference type="OrthoDB" id="10686724at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="196"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="81"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="216"/>
            <end position="226"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2431957.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="585" mass="59049" checksum="91C6A964351DE200" modified="2021-09-29" version="1">MPQVLRGDIIESEELAELRDEVLAKLLPAPPRRAQPDEVLAHARAEAHQQAAVFNDSRLAHLQLIHQQHNSLARLQYGDAEADLREAAEAAEVRAQQAAQRTLELIREQEEEDRKARALLAARCSVDSTLHTGVGVSVGAEAACAGSDGAAVRASVGSGRSAKGVKLHASSMAACAAEAPAEITMSRYIVAPAPARFLTTQPPPPPPSQPQEAAPGGAGTGAGGAAAPGAAGPHATHAFYAGSRHASFGRRNSGGSGGMAWHGAPLELPGGGAAVNAPASGGAGGRFVSAVSPWPAELPPSTHGIGAATFSPAAMRSPAPSMRRRSSAADFLLDSVPEVAAMAAKGSGAPSPMLQHLLQNPHQHQQYALHPTPPPPVYLHSGSMAAAATGSGCPSPAPGSATAAGFRSAGTPLAAAHTNSGRGLQHWGSDRQRFGSTSALMAATVAGVVSKAAVAAAQSEAEAEFAADADADVQAAFGGGSEMNTGQSSELDAVVAQVELLQQQRATLHTPPPHQARIHSRPQSHPHQMQAQQGLVGTLASSGCGSASGKRAHQPPLLAAVAAPAAAAALAATTCSCAAAARRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SV30</accession>
    <name>A0A835SV30_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF4386 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013716</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000079">
        <property type="protein sequence ID" value="KAG2430353.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SV30"/>
    <dbReference type="OrthoDB" id="547559at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025495">
        <property type="entry name" value="DUF4386"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14329">
        <property type="entry name" value="DUF4386"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="12"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="50"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="81"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="145"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="176"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="206"/>
            <end position="225"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2430353.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="244" mass="25080" checksum="08B46C2BF93CBA01" modified="2021-09-29" version="1">MENRDNYFSPWAARTFGFILLWAFVAYGGGDSWMVSLRAKHLSSLSFSGPVAHELGVVLLGALLFPLLWHHGAPGVAAGYLATRVAEALLLAAGVVAQLLLVPLSAARLTGDGGSAEGSAAPRTGGGRGGGGVSRADLADLLVSANFYCFQIAMLALGLGSLPVCLLLLRRRLLPAWMAAWGLLGYSLLATGCVAELHGAREGTGVALAIPGGLWEMALGLWLLARGGFLPGNSGGASSAKKQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SVT3</accession>
    <name>A0A835SVT3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">SRCR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_012464</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000059">
        <property type="protein sequence ID" value="KAG2434003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SVT3"/>
    <dbReference type="OrthoDB" id="535530at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.250.10:FF:000006">
        <property type="entry name" value="neurotrypsin isoform X2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.250.10:FF:000011">
        <property type="entry name" value="Scavenger receptor class A member 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.250.10">
        <property type="entry name" value="SRCR-like domain"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001190">
        <property type="entry name" value="SRCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036772">
        <property type="entry name" value="SRCR-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19331:SF465">
        <property type="entry name" value="EGG PEPTIDE SPERACT RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19331">
        <property type="entry name" value="SCAVENGER RECEPTOR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00530">
        <property type="entry name" value="SRCR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00258">
        <property type="entry name" value="SPERACTRCPTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00202">
        <property type="entry name" value="SR"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56487">
        <property type="entry name" value="SRCR-like"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00420">
        <property type="entry name" value="SRCR_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50287">
        <property type="entry name" value="SRCR_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="4" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="domain" description="SRCR" evidence="6">
        <location>
            <begin position="339"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="6">
        <location>
            <begin position="441"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="6">
        <location>
            <begin position="540"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="6">
        <location>
            <begin position="642"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="6">
        <location>
            <begin position="744"/>
            <end position="841"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="6">
        <location>
            <begin position="1055"/>
            <end position="1163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="841"/>
            <end position="881"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="844"/>
            <end position="878"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2434003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1164" mass="122971" checksum="E63E4C426B20E4DE" modified="2021-09-29" version="1">MPVAADLLRNTVLCRGSLLDKLLTCHDRGNSSGRGGGPDACSSTPGCVWTTRSAVEPIPEYLDLIEGGGANVRVANASAAAAAGLNTTAGNATYLYDPVFDADNMVTILQGFMRYLTGAPWPSYSAGAPNTLCTARWATDRERLAQVYKQYYKQTDMTLDGSDTDEQWALKFYGSPSAAYLFGTCAAARTFLSAALRCGTSASSRAACTAQPYCDYYQEGSSGGSPQAGYQSCELGRLEPLAAADPAIFLSDPWGAALTALAAKCMPLQDAASGRRYGSADCGEYRQSAEGRRGLSAQFDAAVQLAAPGALLNPANLRPSYYVPPDTADQAASGATRTVRLVGGSSPTSGRVEVLYNGEWGTVCDDYFNFTEASVVCRQLGLGQYGIPYTDGRGSGAILLDDVRCSPNATRLEDCASRGWYTHDCSHSEDVGVTCSPSRPLRLVGGSSPTSGRVEVLYNGEWGTVCDDYFDVKEASVVCRQLGLGQYGIPYTDGRGSGAILLDDVRCSPNATRLEDCASRGWYTHDCSHSEDVGVTCSPLRLVGGSSPTSGRVEVLYNGEWGTVCDDYFDVKEASVVCRQLGLGQYGIPYTDGRGSGAILLDDVRCSPNAARLEDCASRGWYTHDCSHSEDVGVTCSPSRPLRLVGGGSPTRGRVEVLYNGEWGTVCDDYFDVKEASVVCRQLGLGQYGIPYTDGRGSGAILLDNVICSPNATRLEDCASRGWYTHDCSHSEDVGVTCSPSRPLRLVGGSNPARGRLEIVNDGEWGTVCDDYFGTKEATVVCRQLGFASGSFYTHGAGSNAPIWMDDVNCTASASRLEDCNFPGWGRHNCDHTKDVGVSCSMPFPSPSPPPPPRPPRPPKRPSPPRPRLSPPPLPRPSPAFVTPLAGPTGFLLFAMGYVPKDGNTPAYFSKFNVDALAPGSEALAYVGAYVPAPDPAGPPTRAPDFPACLPDRGWDDAAADLACRIAGFASGRATLTAPNLQLPEASTMVVNVACPLSRATRRAEPQDCTANLRRQSAGMCTSMLAAVCTTARLASPSPPPPPSPPPPKRPVPWLRLVRPAGVSASSTLGRLEILYNGEWGTICADGFSSTAATLACRALGLGTSGRVIPDYTALFDAGTGPIWLADVGCWAVSLADASASLADCTHVAPHCTHEQDVGVRCVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SW56</accession>
    <name>A0A835SW56_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013529</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000076">
        <property type="protein sequence ID" value="KAG2430998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SW56"/>
    <dbReference type="OrthoDB" id="560105at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030149">
        <property type="term" value="P:sphingolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393:SF6">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="206"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="255"/>
            <end position="277"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2430998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="285" mass="29932" checksum="83FF344720406788" modified="2021-09-29" version="1">MFAAVAAGCPLPVLQHRYQRWLAFQGLGGLAAMIAHVAHVSLLPAFEAALGSSLPDWREKCEYLLTQKPLDDFVSFHGDRKEADEEYYPAAIDSTEAGPYRWAAQQPDYAQRLRYLYSLRGRTKEERVPPRRLAAEAAAAWGREDALIYLLDECGLQIGHNVAHTAARAGQLRILQLLRQRRLTVFESHPDLAGGAADAWPLDVRGAGGGGGDGPVGAGPPGAQGPGAVGARLHAGGPTRLRHGHARVPARAAGRAGGPGGGGGGRQRGGAGVGAGAVTGSARRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SX85</accession>
    <name>A0A835SX85_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Non-specific serine/threonine protein kinase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_013320</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000072">
        <property type="protein sequence ID" value="KAG2431628.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SX85"/>
    <dbReference type="OrthoDB" id="63989at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990604">
        <property type="term" value="C:IRE1-TRAF2-ASK1 complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036498">
        <property type="term" value="P:IRE1-mediated unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd10422">
        <property type="entry name" value="RNase_Ire1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1440.180">
        <property type="entry name" value="KEN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045133">
        <property type="entry name" value="IRE1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010513">
        <property type="entry name" value="KEN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038357">
        <property type="entry name" value="KEN_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036855">
        <property type="entry name" value="Znf_CCCH_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954">
        <property type="entry name" value="IRE1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13954:SF6">
        <property type="entry name" value="NON-SPECIFIC SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06479">
        <property type="entry name" value="Ribonuc_2-5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00580">
        <property type="entry name" value="PUG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90229">
        <property type="entry name" value="CCCH zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51392">
        <property type="entry name" value="KEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <keyword evidence="4 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Protein kinase" evidence="9">
        <location>
            <begin position="1"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="domain" description="KEN" evidence="11">
        <location>
            <begin position="214"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="727"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="768"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="727"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="7">
        <location>
            <begin position="768"/>
            <end position="796"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="456"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="578"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="476"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="507"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="543"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="578"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="628"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="12">
        <location>
            <position position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS51392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2431628.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="833" mass="81463" checksum="3B04C8C556D7A31E" modified="2021-09-29" version="1" fragment="single">STLCDYLATPAGRGQFVDPVTQQPTARCMAAMLDICRGLAALHERGIVHRDLKPHNVLLTETQAAGGHGHGHHHHHPSRAKLSDMGLSKQLVPEQSSFHLLDGGSTHGPGGSSGWQAPEQLIARGGGAARQTRSMDVFSLGCILYYCMTGGRHPFGDNTYERDANILNGSPALSALAAAAGPEAANLVASCLAKDPAARPSMAAVLGHPLWWGEERRLGFLVDLSDRLENEDREPDQTLLEALECHARVALSGPGAALEGAVAAGAAATAAAGGVGAASSSSGAGAAAAASAPALPPAIAAALAPIPNWGAALPPELISNLGRYRRYDYTSLRDLLRVVRNKRNHFREMPPQLQAMLGPIPGGFQRFFAARFPRLLLAGYAFGLEHLAAEPNLQQYWGGGVGGGGGGGGGGGAAGGAAAAGGSSGGAGEGMGAAGRQPFVQTFVAMYGPNLRPIKSVMPSAGQPTTGTVGGGSSLANGHGTNASSSSTSSLSAAGAAAVNGAGGGSSSTSTTSTPAPPAAAAAAAPAAGGSGGSSSTSSGKEGASGGSDAGRAAAGGGASEATAWRTAAAAAAAAAGASSSSPSEPTSAEAAEAAAAATAPAGAMPDSTPSKSAKKKQQQQQKQDGAEPPPPPPLGTPPPPAVAAAAAATATEPAAAAAAAAATPNGAANSAATATAPASVAATAAPATACAAATAAAPASPSTLVLVGYEPCGDDGECHVREFPRRPGKQLCDFYAKTGHCKFADTCVFDHPPEHAVRLTALGLPLRPAEPVCTFYIKNNDCRFGPACKFHHPLLRPVFAGSAQVSGPGVGAGAGAGAGAGAGAGAGAGAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SY95</accession>
    <name>A0A835SY95_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014454</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000096">
        <property type="protein sequence ID" value="KAG2428106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SY95"/>
    <dbReference type="OrthoDB" id="542443at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="178"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="206"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2428106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="296" mass="30886" checksum="E1A9D3DC5552A6A8" modified="2021-09-29" version="1">MPAATGEDVRATTKKRAPCSAKYAVHLMVPASPPYKEAATVVGPRHVATYAHEDHLSWQSLRSQVAVHCPDEDRRTHVDATVVYHDKDKDVVILEVQRELAAPVLDTAISAGDMYYVHGHGQSTAAQEADATSISHGRVAATELDALSHRGDIRGDMTWGKGDYSGGGCFSVAGHRQAHGPGGRVGCNHQEGHPGAHRGHQQHPDGPGSAATAPGAASGMRSLLTWRLQTARPVLPVPRAQAALCVFTAWAKAVKAQVGSARGARHAAEGVGVAAAQSLAARPSHVRGGVRGGGVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T1H6</accession>
    <name>A0A835T1H6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Serine/threonine-protein phosphatase</fullName>
            <ecNumber evidence="13">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HYH02_013567</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the PPP phosphatase family. BSU subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="13"/>
    <dbReference type="EMBL" id="JAEHOD010000077">
        <property type="protein sequence ID" value="KAG2430725.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T1H6"/>
    <dbReference type="OrthoDB" id="309851at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009742">
        <property type="term" value="P:brassinosteroid mediated signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07419">
        <property type="entry name" value="MPP_Bsu1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.60.21.10:FF:000008">
        <property type="entry name" value="Serine/threonine-protein phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041758">
        <property type="entry name" value="MPP_BSL_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006186">
        <property type="entry name" value="Ser/Thr-sp_prot-phosphatase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012391">
        <property type="entry name" value="Ser/Thr_prot_Pase_BSU1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46422">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN PHOSPHATASE BSL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46422:SF4">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE BSL3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036363">
        <property type="entry name" value="PPP_BSU1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00114">
        <property type="entry name" value="STPHPHTASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00156">
        <property type="entry name" value="PP2Ac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00125">
        <property type="entry name" value="SER_THR_PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0880">Kelch repeat</keyword>
    <keyword evidence="9" id="KW-0464">Manganese</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="Serine/threonine specific protein phosphatases" evidence="15">
        <location>
            <begin position="648"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="58"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="422"/>
            <end position="458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="835"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="432"/>
            <end position="449"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001936"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022912"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023211"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU004273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS00125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG2430725.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="888" mass="95864" checksum="1345D4237B0D5CD7" modified="2021-09-29" version="1">MVDMDSDLRPSPVPRPRVFPVVGTAPGPRCGHTLTAISGPEGDLSKAKLVLFGGATALEGSSGKSESTQSTPGSAASGIRLAGATNDVHIFDVRTGKWEKTTPAGEPPSPRAAHAAAAVGNMVVIQGGIGPAGLASEDLHVLDFTDPDRPRWHRVLVSGPGPSARYAHTLSLVANRFLVAMGGNDGKSTLGDAWALDTSEKPYAWRKITDAGEMPSPRMYATAAARSDGLLLLCGGRDISGTPLGDAYGFARHRDGRWEWHSAPGAMPTGRYQHGAVFVGNRLHISGGAVGGGRMVDESTSTVVLDTTHGCWVTPVGGATGEDFTRRCRHAVASVGPFVFIYGGLKGSQLLDDLLVADDSNGTELSIFDPRSSAWQQYMETMHGNAAASRMLEKAAAEEAAAAAALNVRRVSAMDDLRCVDEQLDGTGAGGSRTSDSPSTNRSSSPDVSLGKDHIPGTTPYTPDVKLWHRAVVVHQENSLRGLVRQLSIDQLDNEGRRVSIYENGGGPGGAKEKSPLFTRSMSVTGVHKRVINELLRPRTWKAPDDRRFLLNAQEIEELCNNAERIFREEPTVLDVRAPIKIFGDLHGQFGDLMRLFEEYGTPSTAGDITYIDYLFLGDYVDRGSHSLETICLLLALKIEHPRSVHLIRGNHEAHDINALFGFRLECLERLGDEPGVFVWRRINELFNYLPLAAIIEGKILCMHGGIGRCIHKIDQISELKRPITMEDGGPVLMDLLWSDPTTNDSVQGVQPSPRGPGLVTFGPDRVKEFCKNNNLQMIVRAHECVMDGFERFAQGHLITLFSATNYCGTAGNAGAILVLGRDLVMVPKLIHPLPPNTPHTPDSSGGLDEDPPTPHPANDTWMQSINDERPPTPPRGRPHMGSSLEYF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T2J7</accession>
    <name>A0A835T2J7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013696</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000078">
        <property type="protein sequence ID" value="KAG2430700.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T2J7"/>
    <dbReference type="OrthoDB" id="2013972at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041698">
        <property type="entry name" value="Methyltransf_25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050508">
        <property type="entry name" value="Methyltransf_Superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42912:SF68">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 11 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13649">
        <property type="entry name" value="Methyltransf_25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase" evidence="1">
        <location>
            <begin position="181"/>
            <end position="288"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF13649"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2430700.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="359" mass="39394" checksum="7E2FF7B00B7CE7E2" modified="2021-09-29" version="1">MQLQQIKPFQQARAGPVRQQPVRVVCQASTTPAAPGRQFNPLLMGTVEALFRFPPFFNAAAKNARGMIMKRAEALGLDWNSAMAELKAQDWEARMKEVTNPNITYPAYYTQPFHAYSQGNLCWEAALEVTMAAKSVHAMVMDPAGKKMDPAGDAALRSSYSARMAESLDQLGVDRSTVKHIVDLGAATGLSSLELLRAFPQAHRVTGLDASPHFLAVGKWEQERRVAAAGGAPREEEKLVFLHGLAESTGLEAGSQDLVSMCLVCHELPQAATKAIMKEAFRILRPGGAMCIMEMNPESAVFQRIFGNPFAYTAFKSTEPWLQEYIALDMPDALREAGFAEVVTRESTPRHKTVVAIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T405</accession>
    <name>A0A835T405_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SRCR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_013375</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000073">
        <property type="protein sequence ID" value="KAG2431390.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6477838at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.250.10:FF:000016">
        <property type="entry name" value="Scavenger receptor cysteine-rich protein type 12"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.250.10">
        <property type="entry name" value="SRCR-like domain"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.20">
        <property type="entry name" value="Vitelline membrane outer layer protein I (VOMI)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001190">
        <property type="entry name" value="SRCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036772">
        <property type="entry name" value="SRCR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005515">
        <property type="entry name" value="VOMI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036706">
        <property type="entry name" value="VOMI_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48071">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48071:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00530">
        <property type="entry name" value="SRCR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03762">
        <property type="entry name" value="VOMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00258">
        <property type="entry name" value="SPERACTRCPTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00202">
        <property type="entry name" value="SR"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49478">
        <property type="entry name" value="Cna protein B-type domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56487">
        <property type="entry name" value="SRCR-like"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51092">
        <property type="entry name" value="Vitelline membrane outer protein-I (VMO-I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00420">
        <property type="entry name" value="SRCR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50287">
        <property type="entry name" value="SRCR_2"/>
        <property type="match status" value="11"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="2327"/>
            <end position="2354"/>
        </location>
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    <feature type="domain" description="SRCR" evidence="11">
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        </location>
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    <feature type="domain" description="SRCR" evidence="11">
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            <end position="1221"/>
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            <end position="1532"/>
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        <location>
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        </location>
    </feature>
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            <begin position="1665"/>
            <end position="1707"/>
        </location>
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            <end position="474"/>
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    </feature>
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        </location>
    </feature>
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            <begin position="1484"/>
            <end position="1509"/>
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        </location>
    </feature>
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            <begin position="2004"/>
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        </location>
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            <begin position="441"/>
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            <end position="3378"/>
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            <end position="4482"/>
        </location>
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        <location>
            <begin position="4550"/>
            <end position="4560"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2431390.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="4739" mass="477873" checksum="78554651BED5D33E" modified="2021-09-29" version="1">[encoded data, 4739 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T5S1</accession>
    <name>A0A835T5S1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">G-patch domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_012375</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000058">
        <property type="protein sequence ID" value="KAG2434359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T5S1"/>
    <dbReference type="OrthoDB" id="4822at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000467">
        <property type="entry name" value="G_patch_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47650">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47650:SF2">
        <property type="entry name" value="ZINC FINGER CCCH DOMAIN-CONTAINING PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01585">
        <property type="entry name" value="G-patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00443">
        <property type="entry name" value="G_patch"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50174">
        <property type="entry name" value="G_PATCH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="G-patch" evidence="3">
        <location>
            <begin position="420"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="165"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="257"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="295"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="574"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="34"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="180"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="262"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="320"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="334"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="349"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="371"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="584"/>
            <end position="596"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50174"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2434359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="660" mass="67248" checksum="A28D1718A89DA371" modified="2021-09-29" version="1">MEAELAEQLTSQREALASIQEAIASIGGDAADGAEELLQMREELVAAVSELEAALLDLKKSRILQQLQQKAAAAPDGAGGAAAPAARLGAGGGGDGEGCTAEAAALPVAPGRTCRFRYMDGRWYAGRVQGRGRQPDTVSVTFEVPTRPFMLDPVDVLCGLVQPYDPAQQPHHQHQHLHQHQYQYHQQQQQQEQPPRIHGGGAAVTAATAAAQPHGHAHGVAVGRRALAQLPGSRLYLPVEVVALDWARATATVLPLLQPPAGGSGSRGGGGGGGTGPRGEVVVSLERVARHTHAEEVAAAAAAAEAREEGGDADGGDGGSESSDSSVSALLRPAGGGGSEDSGSGSGDEYGDGEGDEDDGDGGEDMYSGEGADDYGGDGEEEEEEEEEDGGLDVFGHARAAAAAGALGDTARFADWDAHGRGVASRLMARMGYVAGRGLGLRGEGVMAAPEVLLLPERKGLGAVDPNRVRRVGGGKLAAAGGVDKKRRRGGAREKRKRAIAAAREARAEVREREDGAAGGGGLFDFINSSLGDSSAAARIRKAQTSVAGVGGAAGGGGGTAGAAAIASAVAAASGGRGGPAAPPDRRGLMSHHDHVSGIQTKLARLKEMLGRHVGNKGMRAQIEAQMRGAQAELAAAQSAAARVSKAIHDKDAQKKWMKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T615</accession>
    <name>A0A835T615_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Flagellar associated protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012827</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000064">
        <property type="protein sequence ID" value="KAG2433125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T615"/>
    <dbReference type="OrthoDB" id="568015at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="99"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2433125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="164" mass="18356" checksum="2C3AD2CF3D80118C" modified="2021-09-29" version="1">MSEGAGPSGFRNVEPQTREERAAARDKDLLEKSRLQARSRVGPLKEPQNFMGSPVVPARNAPAFCDEYDRFNRDVAGELNAKKQQNLQKKEEVYAIKRAEQYHRERSNWETQAQAAAREAARLEASRTTGMGAKRNQGSESYNIISLSYNNTSGGQQLAAKVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T760</accession>
    <name>A0A835T760_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">JmjC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_010943</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the JARID1 histone demethylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000044">
        <property type="protein sequence ID" value="KAG2438242.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T760"/>
    <dbReference type="OrthoDB" id="415358at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.650">
        <property type="entry name" value="Cupin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.10">
        <property type="entry name" value="Jelly Rolls"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041667">
        <property type="entry name" value="Cupin_8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003347">
        <property type="entry name" value="JmjC_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014710">
        <property type="entry name" value="RmlC-like_jellyroll"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461">
        <property type="entry name" value="HYPOXIA-INDUCIBLE FACTOR 1 ALPHA INHIBITOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12461:SF102">
        <property type="entry name" value="LYSINE-SPECIFIC DEMETHYLASE JMJ31"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13621">
        <property type="entry name" value="Cupin_8"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00558">
        <property type="entry name" value="JmjC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51197">
        <property type="entry name" value="Clavaminate synthase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51184">
        <property type="entry name" value="JMJC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="JmjC" evidence="3">
        <location>
            <begin position="182"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="404"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="438"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="662"/>
            <end position="696"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="776"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="829"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="83"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="131"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="142"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="167"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="451"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="664"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="781"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="866"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="894"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="909"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="920"/>
            <end position="948"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2438242.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="993" mass="98476" checksum="C60BC7946A4C5CB1" modified="2021-09-29" version="1">MRWAESASEPVLFPGLLQDWPALRRWRGNEGLRHLANLAGAADVQVMVSRSRAFYGDISRHQPATVAFRELLRMLEQQQQQQQQQQQQQQQQRVEERCEQGGRGGSGGGEEEKEEEGEEPPQGEVQGGGAEQERPCGRGDEGSSSSSSSSEEGSSSSGDEGGSSSCSEEEEEEEDADDAEGAGSVPHIYLAQQPLTGALAALRRADEAPTPACLASTRLASVNLWMCGGPVRSSLHYDPHHNLLAVAAGRKALRLVPPPYTPCLYPMSITGDAPNHSSVPFAAPRAALAASHPAYLAALAASRTAELQAGDALFLPEGWWHQVDSGPEVTIAVNYWWKSGLGKLLAAGAAGEGGAGAGSGAAAGAGAAAGAGAAAGAGAGAGAGAGAAAGAGAAAGAGAGAGGVGSCGTEGSGNQTSSGGDAGRAGEAVVTAAAELAPGSAGGGMQPRTLAADGCSAGAHSGSSSSSSGGSSSWGAGLANLFALRQLAAAAVEDMAEHLLRAAAAPAAAAATAAAPRPHPLPPLAPAAVASKEAVSEGAATADSVAAAAAAAAAAWDAEVRAAAAALSAAVCAARRMQGSGSGGGGGGGSDDSALRAVPEVQVAAAAVASYPQQQQQQQQQQRLDLTAGLLLLLPPGAAARLGLTGCPVAAALARILLLQPAQPSQPEPPSQPHQPPPQTQDATADPPQSLPGAVCASLAPNRHNRHHQPLPPAAHVLLAHALHRLCVTQPAAAAALVRRCCVVPAAAALLSRAFDLLGPEEEAEVEAGAEAVEAAAEDGEQGKGVRVEWTREERTGLERQREEPAAEQTAVAAAAAAAAAAAAAAAVPSCGSGGMRKRPTPAVAAEEGDGQQGREGQHRQGKGQGRQQQQRQQQQQQPSASASAAAKRARKSPPSPPPPPPPPPLCPAAPGGAAAVPREGGGGADSDSSSGGGGVGGGGSGGGGGYPGHAAFFQQLYAVASEEPDKVFAALLAGRAAVHAAARRLLVEHVLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T7V6</accession>
    <name>A0A835T7V6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_012719</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000063">
        <property type="protein sequence ID" value="KAG2433176.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T7V6"/>
    <dbReference type="OrthoDB" id="21204at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051826">
        <property type="entry name" value="E3_ubiquitin-ligase_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765:SF411">
        <property type="entry name" value="OS02G0248440 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22765">
        <property type="entry name" value="RING FINGER AND PROTEASE ASSOCIATED DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="323"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="484"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="538"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="678"/>
            <end position="708"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="910"/>
            <end position="1030"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1056"/>
            <end position="1092"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="63"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="375"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="484"/>
            <end position="501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="502"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="541"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="554"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="682"/>
            <end position="702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="964"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1061"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1071"/>
            <end position="1092"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2433176.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1092" mass="104564" checksum="94ADE0C3D63533C4" modified="2021-09-29" version="1">MERPSGPDRSANVHVRCYSCSRVSTIAAAGSETEHARCPHCQSDFVEFVDAPAHAAAGGSSIPPRGEAAGAAGTAAQPAGPHPHGTRFEFRATFDAGGGAGAGGPGARPGLSLVDAVSRFAPLRLPNGQQAFALQVQDGALMSPFTMELPFGLGPGMGPMGGMGAPAAPGAGGAAGGAGAGFALNPSDWVVGEDLDAVVSRLLDAYVPPRSSATQETIDALPRLRVRPGPLSPKPAAGIEAAAAAVDAAAAAAAASSSPAAEAAAAAGGTSTSSEERQEAAAAAVAASAAADAAAGAGTSTTTSSTGGAHGGGYASCQPGELCTVCHDPFEAHGEVVELPCKHCFHGDCIVPWLQQQSSCPVCRTKLKQRRGTVPGQPAQPHQQPQAGAAATAAAGAAAATAAAAPVATGAGAPPRGGMGLMFSAGGGGGLPFPMSFLMPQAAPQAMPAPRPLLTPEERAAAEAALEGLRTRFAPLTLGPTVVGATGRGPAPAPSATAAAREGGGGGGAGVGGGAANWSPAPLRGGFFNRPAAAAAATSGAGAGGAGGTGGTGSSSSTSRSALRGGFFNRGRSSAGGASATAGSAPSAAPPSSSSLPQQPQPQPQLLRGGAAAAGGGGGGGGGLASLTMGGLPMEALMASMMGAGPLRPGGGGGGGGSSADVTDLMSRIMWVTALSAAMAEEQAEQEEEQEEEQEEEQDEAAEAAAAAAAAAATVTVERMASSGNGTAGRVTIRLPAAAAAAVAANDLRAMCGMMEAGALHSLERSVAAADAAGEARPTEEELRQLQRRTLDDCERKVRQLSLLMPDPTGAVMRGIAAASDNWLVHAQEVLRRPPAELAAAVAARRRRVAAARHGPAGRVSGSGAQEGSAAAAGAAGAATSAAAAASAAAEGSAGSSDCKAGEPAAAAGALGRGTKHGEAGGDGEVCAASDSEEARCEGPSRQVLRRSQGEDAASLANVALGDSSSSSTPAAAAAAGGRRVRVTAAPRHGGAARAGAPRHPQQHAAAAPASGQGAAHSSGENRRSGGGGGGGLNPVSLVVGGAGAGLRLLGGLASGLLRRGSGGGRGASAGGAAATPAGAPGDEAPGAATAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T998</accession>
    <name>A0A835T998_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Chorismate-utilising enzyme C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_011650</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000050">
        <property type="protein sequence ID" value="KAG2436144.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T998"/>
    <dbReference type="OrthoDB" id="1865897at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000162">
        <property type="term" value="P:L-tryptophan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.120.10">
        <property type="entry name" value="Anthranilate synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005801">
        <property type="entry name" value="ADC_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019999">
        <property type="entry name" value="Anth_synth_I-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015890">
        <property type="entry name" value="Chorismate_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236">
        <property type="entry name" value="AMINOBENZOATE/ANTHRANILATE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11236:SF9">
        <property type="entry name" value="ANTHRANILATE SYNTHASE COMPONENT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00425">
        <property type="entry name" value="Chorismate_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56322">
        <property type="entry name" value="ADC synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Chorismate-utilising enzyme C-terminal" evidence="1">
        <location>
            <begin position="39"/>
            <end position="64"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2436144.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="87" mass="9013" checksum="38811829E6578EE0" modified="2021-09-29" version="1">MDMALGLRTMIIPDAAADTLYKYTGGPAAPGAPPRREWSVHIQAGAGIVADSKPEAEYEETVNKAAALGRAVDLAEQAFVADGRSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TAG5</accession>
    <name>A0A835TAG5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">GBF-interacting protein 1 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_012295</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000057">
        <property type="protein sequence ID" value="KAG2434465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TAG5"/>
    <dbReference type="OrthoDB" id="548783at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd14279">
        <property type="entry name" value="CUE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009719">
        <property type="entry name" value="GIP1_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051833">
        <property type="entry name" value="TC-DDR_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009060">
        <property type="entry name" value="UBA-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16308:SF13">
        <property type="entry name" value="PROTEIN LINGERER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16308">
        <property type="entry name" value="UBIQUITIN ASSOCIATED PROTEIN 2-LIKE/LINGERER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06972">
        <property type="entry name" value="GIP1_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46934">
        <property type="entry name" value="UBA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GBF-interacting protein 1 N-terminal" evidence="5">
        <location>
            <begin position="7"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="44"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="588"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="871"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="927"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="51"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="109"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="133"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="173"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="262"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="588"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="628"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="886"/>
            <end position="897"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF06972"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2434465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="964" mass="92331" checksum="56C2D0FC29CF954E" modified="2021-09-29" version="1">MSDKQFPKKVIEAMKEATGASEEDVKSMLQACGGDVNVATEQLLVNPFKPANEKKERKAAHEADRRTDSRSGGRGYDRFANGGAGRGRGRGEGGRGGRGSGYATGRGSTGAPSGRGPSAGPRGQQSSSAATDSNGAAAHAGSSWGAQGATDADANAWGTAGTSSWPSEKPAEASTTSTSTAWGSSAPAAASTSGSAWGTASATTGDNNASSSAGATSSNPAPIRPGTGMTMAEKLKASQAKPPAPAPAPAPAPEPPKPAPAAPAAASSSAPTEPAASSSDATSTSYAAPAAAPAAASTWGADAGKNLMGMLGAGKAAATSTAAAPAAAAAPAAAAPAAAAQAPAAAAAAPATADKVVTLSAADNQVAPPTASSQAAYPAYVAAPAPAAEAPKAPAAAAAAPAAPGQAADVDTLQLSFGAFSVGGGLADFGANFSASYNGQPADASKAAPAAPAAAAAAPAGAPAAPQQPGAEAAQPGAAAAASVADQYKQAYAQYAMQAAADKAAGAPGAAAGGADQAGAGATYGSFPSQAAAAAFGNAFGGAGFGAGQVPDTSRGVFGGQDYGAYNQEALKQATQAAYGQAPAGQAAAGGYQQPAQGAPQAPVPAQGAPQQQQGVAPQGGPQGGPPGMQAQQYQQYQQYYGQQQQAQQQPAAAGYNQAGAKYNPATGMYGQADLNAAAAASSAAASTTAAGAAPQQQQGAPAGAAGAAAAGGMPQYGAAPGAIPPAMQFNAAAGAASHLPYSGYQNPYNNPAFAAAMYQNPYLYYQQMGYQQAYQAPAAAAPQQQPYLQGGQAHMGQRTGGFPGYNAANPAAAGGLPAGGYNANPGAAYGLTGYEDSSNAAAGVNAAAGGAGAYNVPAKQADKQDPSALGGYGMGGQQMPQQGMQGQGAPAGQGHMGGHHQGGHQGGYGGYNQGGYGGGYGNQGGYNQGGYNQGGGHYGGGGYGGNRGGYGGNRGGYGGYNRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TAI5</accession>
    <name>A0A835TAI5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_010370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="553329at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
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    </dbReference>
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    </dbReference>
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            <begin position="1"/>
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            <begin position="2262"/>
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    <sequence length="2448" mass="242248" checksum="2A92788BE6AAD036" modified="2021-09-29" version="1">MPLQPGHANAGGGAAPKAEPGLPLGQVAQPPRPRIAAQASGSARGLLPPLPGGAAPQTQMPHVPAGISAKPPQQAQQGKLPTGAGSSMAAAPSSQLPAAGVPAAQAAPRHRTLLNYALTVFPSRLAQLAPLGMRLRSGSACGGDVGQGQAAVLLPAESLQQLQTVAAAVQDALVKAGACVGGGGGGAGGTAALTVADREDVWRLSAACWEAAVAAAASTPPPDTPARAEEQSKLLHGLGSAIHEVALDPAAGFGAVAGGCGGCSGVRLLQRVRFLHQMGRAWLALGRCAPAGWFLVRAREGLGQLQAEAAEARPAPEQPQQRLRIKRARLSAPPHQDASDGSGAGVEAEGVGEVGHPDAAEEGACGGAGTSQTGAGGDGGGPWLALGLGCEEYLQVESDVLVESLRLALAEGQQALSANLRSQLRRLATSPHTPPGLAATSALTCMAILTDAAAIRLGAGAVDGASGGLGVASAPPQGGSSGNQLQPQAQGDAMALLGDALDVVEAAAEAEARRPAGAGRDEAAVERAAALVEARQQVLRFLISSCLRTASYQAALSYVRAFAESTAPAAAAGEGVASAGNAETVTAAEAAAAPPPLLAAAGTRAEADLPLDVLLLSVQAHVGLGRMVEAAALVAARVQPHPACTPAVMKAALSRLLGGASLPQLSASMPHLTACLLASLERCGRQDDAAVANLHHNGAAAQPGDAVLVGAGAWNAAAGGELVVLVSSALCAHEGRTAEQLLLALLALDDVVAAVCNSGSGSGGAGGGADGGSGTRGSARARLFGMLYARAAAAFQESDYEGAARLFAAALLYASGGGGAPYCRTARMLSACYAAAGQPDRALGYLDLAEAVEPHTAAHVLLRLRLVLALQQAEARTGPAAAGESGGAAPRHGGAGAGAAAETQGGAGGGDAAPGLGDGAAGGARAAGDGEVVQLVQRLPRCCDFELSHLAVAYDVAMRAQRFGVAVTATELAMRYLGPPPRQAATLIITGAAATAAAGALHAAIALARDCIAGRLAAVAAASSQGASVSRSGSRRAFAAPPSADSGAPLPLAAAAAVLRDLLWLCSRLSDAAAAPLTAQAQASLSWLRDVAVRLGHDALNGGRGLQPPAESQWRAAAAALRAAQQLDSALLLQGATASTATAPQQQGLLLGRREALRQQAAGSDAAQRQLQPVMVAVAAGMLATYATHAQASAAPGPNWGPSSALACAAAAARGVGVGSLPPPDMALVVEAQQLLEGCRCAGSGHCAPEAEPVAASPAASAAAASRGGGGAAMRGAVLQLRFVAATLAQDEAEQRALLQALVDEPAVCGRRMEALASLCLAPDTPWRCIRPGCALLSFCIRKGLPLPLPRPPAPVLRHALGGAVSSDVPSAGADYAPSAAMDVELVARAVRRLYAEGSSDLRVIVCKRAIEIATQLCSAHHDHVDDTGPATQDAVTAERAATTDMRVACRYPRVELHFLWAACLNAAVAAELSASALGMIASRDGAAGAPLLLDLASGLLRQLEDGGAEGGAAASGGGGSGGHQGSGASSLRTMWLGIFRSVSKQPRGHSGNSPAPAAAAASAAAGNIAAGRRTDPPPQLALPASSPATLPLAVQTPAPGLPAALPSQSHQQLAPPQPAESQLPVLHPSEQPQELRRQGSERGGDAPLGAAPQSHSQLLEQTDEVIGLEVQTGHPTVAPGPMQQQPQAVLPSSSQGVQSLGAFTRTEGVDAPEAMAAEAVRGEQATGTAHPQQPEQPPDMESDKRAGADPLPARVPALPCSDGAATDAAAAEPTGSGTAVAGATAAPVAGAVYAADMGSRQRRHHASFPPDMCDVEAWRSPGAASGGNAAAAGTAESATQLGRYAAAAASLQPPAWTLEGTAPDVPVQQGRASLGHALDTPAGISIVPKGAQPTVGAVRLALAPSPRAPPLRKPDAAMSPRRAQTTAGSAHASGSKQEAAVQQSLATAGSQTSLLSECYGGQPDPALASLMPPHGRITPGGGDRGLGNAGAGRTCRGGGVGGWLGSVLPMLPEGWRDATQLDADADIAGVQNATAASEQASAEAAATSQVCTLAAPPAVKVAPSPGVDLPCGRHAPGAVARTPPPSHPTASCPAMHPKQQESGAQGNAGMSQQGPAAQVDGAEGLVAGDEDGEGEELSPLPEQADPLERRSPEAVVLLARQSPPAMPLLQPGSPSACSAVARGPSALPASQRGQPVQLGQSPRKADAIRAGEAEQTSPLASERMSVADTAAAAAGAGTTAPAGTGTIAPAPVQPEHSPSSAGAPNAANAAAPAAGEVGQGAVAAPAAPKPAAARPRLSDSDINLEELDTCVAADEVAAAVLPRDADGPTTAPAAEHISQGQGSLGVPAGAVQAGLVQHAVAPSDGGHGSAKRAEGPTGAAEERAAKRIRTDAVVGSCSAAPPPFHEIRAMERLSVGVGSDGAAPVPLLVGMGTEYADEADALMLEDW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TDR4</accession>
    <name>A0A835TDR4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_009686</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000033">
        <property type="protein sequence ID" value="KAG2442201.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TDR4"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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            <begin position="1"/>
            <end position="20"/>
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        <location>
            <begin position="236"/>
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            <begin position="358"/>
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            <begin position="241"/>
            <end position="275"/>
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    </feature>
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            <begin position="381"/>
            <end position="402"/>
        </location>
    </feature>
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    </evidence>
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        <source>
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    </evidence>
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        <source>
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        </source>
    </evidence>
    <sequence length="505" mass="49737" checksum="4921AE4A0881FE2C" modified="2021-09-29" version="1">MESSAIAAGGGSASSSSSSGASSLAVHASAAAQQVIGTIGGSPSLLHEQPPSYCSPASMQYNHQLAALQQRRLALAAAGLTSPAAVASCSSRRHLHSQRSQLSALRASARAGSSGYRPNLRAAATSALTAAGDAVAAFNRRAAAEAAAAAAIKADSALEGAAAAAEEAPIPADASADRNGTVTAVDALSARLGAAMELWEQGQLPEALEAALGVLAEHRLLTTALAAAAAAAHEEERAAEQRLQQPQLHLGRQQGQQRRRQQQQQQQQAVAARQGAAASSEAAAWEAASRDLRAAAARLRSQHAHLIRDHAARDQARLAADVLRLVWDLDPYGVAARLMAAAAAAAAAEYGAPASVAGPVPAPPPPPKQGNGSSCSRSGDGVSGGGGVSSGGGGGGGGGGGGGVTGGGGGGCMEAEWDEGVGGDKELALLLIRALTATAVSVEGGPGGVVVSSAEERERLMMAAGALAEAVVAVGLVVEEMEEEEVAAAAAAAAAESKTGVRSGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TE03</accession>
    <name>A0A835TE03_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_011330</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000047">
        <property type="protein sequence ID" value="KAG2437070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10686847at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030149">
        <property type="term" value="P:sphingolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393:SF6">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="417"/>
            <end position="449"/>
        </location>
    </feature>
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            <begin position="663"/>
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    </feature>
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            <begin position="1542"/>
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    </feature>
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            <begin position="418"/>
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        </location>
    </feature>
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    </feature>
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            <begin position="1689"/>
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    </feature>
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            <begin position="1702"/>
            <end position="1719"/>
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    </feature>
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        <location>
            <begin position="1724"/>
            <end position="1733"/>
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    </feature>
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            <begin position="1792"/>
            <end position="1801"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2437070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1844" mass="184409" checksum="BEB526AC620E28F1" modified="2021-09-29" version="1">MPSGDSEKGHWDKLTPDIISRIASSLHENEVAGALKLVCRDVAAVLANYNKLTLGVKRRRDGHWSFYPNQAQQPWPAHAFVLYWGRPEPWRSLSLQQRERLLCLAAASGDAASLEVALAHCACELRSPTLRAAALGGSLAGCQRLLQEGCNFEVNAITDAAECGSLQVLKLVLEASGDPINAGNLSLAALGACAGGHVHVLAWLQRAHGYGPDMCDQFHAARAARGGHVGVLEHVMQSLLPQAPPPAAGAGAAPASAAAAAAATADAGEGAVEGNDRHYVRWGVLEAIAGGACPAEVLQRHLPGLWPDPAQGPSVLDKVDLLAAAVGSGTPCWAAKVDLVLGRWGRAQLLQEMSLMHGRMWDVWMAAAAHDSFMQRVRHLVAHGFSPDKDMLVQAIARGHTDALTFYMTECCNSAPDGGEGTGSDPRGGGAGGGGAGWQGVGEDPGRPGALRDWVDPLLRRGGTTPCVFPGGLAVMRLLLDSGVALTCEHLAGWRCVQDWPEEALVWAAEHLPDMVLEAEASKYRNTPQQCWTEIAGMAARGGAGPQTLRALRARGAELRMDDVVAGGSEDCIRWVAAELEAERPRALEAVDTGILACMFEAGNLAALPWLHSRPLPLPPQQHGWRPRMPSIEQVCRDLDRYTCWRRKTWVLLQQQLLRCQPPTAAGAGQPPPAAAEKQEQQGKRSSEGGAGEADGGAAAGLLPAEAGADGAAAHVWAAVRQEVGRLFAKAGEQAGESNGDGHQRRSSGYELLRYQPASSTLTRLLTEGVRDAKRAARRLSCPLGAGGQQQQAPNVLAFSETLAEGQSDLLPAVAAFRAVLSSAVDKDAELVDAYQRVAGLAGLAACELLLGLGQTEPRDAASAAAHATAALADALSTSYSLACMEAAKASAAAEQGALFAACGHPTGSSRSRSAPNTYGGGGGAGGGSAVGVLGLSLEDRRCQECVLSILGFALAALHATVRSHPEACPRQAHCLLRQLRGLPGVAAVLAPAHRSGGAGGGGGCAAQWEERGWDTSTGAELGACWRPPPGGTGPGGAFRVQLTPLAAADGCEEERPAPQLPPALDSFARFIRQVTDTLQRGLFPAGSTNPGADGEGSGSGGGRLSEVYLRACLEAAHHQVSWELDTTRGVVAVPLQAGSGGSAGALSRGGMAGRGAGGLGGGGGAWLHMGLLAEEEGGEHDAANAGSEDADWAYGHDGDDGGCVDAVSASNRDGAAAAASSSDRAAQHVPPHAAAATIVACPDSPLVVARAGSISGLGPRPAFAAPGAAFSAPATAGVTAASLSAVASSGYSSSSSSWMLGKALSVGPRGGLGGLASPSTLTSASASAGGLPIGNLAAGLRSPAAATAGAAASGGAVQPLRSFSSMRELRSPFAGGGGAAGGGGGVGVGGGGGGSLTSQRRGGLLGGSGGSGILGGGVVAAAALAARTGVSPCSSAAAGSTVVSRAGGLVGGATPVGAAAAMAAAAVSRFGAETLVAAAAANQQQSSGRSGGWAANGLARRTASWTIDGHGGGGGGGGSSLGAAALSSPRHRYAAAEVLDGNNGEGKQQQEERGGADCQGISRSSAGAALGSRQFVVQLQGTARPRQQSANGGLPQGTAGALEAAAATAASVARPQSPISPVAAASGYGPMRYGRSEPGAASSPRHVVCGADEASFGGGCKDTSAAGADDAWTAEGIPAAYRSHEGPGGRGGGGGGGGGLTLRRLPSSSGVSRSAGSGILMPASQQAVTSDSAGPGLGAVPEVPGLTQTTSFNKRNVSFAGVNGMPTIARGFNATPSGAGGTCAEVAGGSGSGTSGGGAGIQITRSSSNSIKILDHRSSGRSFSPSLSIGARSTHAAPLASHR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TE08</accession>
    <name>A0A835TE08_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Plant heme peroxidase family profile domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_009770</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>heme b</name>
            <dbReference type="ChEBI" id="CHEBI:60344"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the multicopper oxidase family.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the peroxidase family. Ascorbate peroxidase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000034">
        <property type="protein sequence ID" value="KAG2441977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004601">
        <property type="term" value="F:peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006979">
        <property type="term" value="P:response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd13889">
        <property type="entry name" value="CuRO_3_BOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00314">
        <property type="entry name" value="plant_peroxidase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.520.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.420.10">
        <property type="entry name" value="Peroxidase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011706">
        <property type="entry name" value="Cu-oxidase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045087">
        <property type="entry name" value="Cu-oxidase_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002016">
        <property type="entry name" value="Haem_peroxidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010255">
        <property type="entry name" value="Haem_peroxidase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019793">
        <property type="entry name" value="Peroxidases_heam-ligand_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48267:SF1">
        <property type="entry name" value="BILIRUBIN OXIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48267">
        <property type="entry name" value="CUPREDOXIN SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07731">
        <property type="entry name" value="Cu-oxidase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00141">
        <property type="entry name" value="peroxidase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49503">
        <property type="entry name" value="Cupredoxins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48113">
        <property type="entry name" value="Heme-dependent peroxidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00435">
        <property type="entry name" value="PEROXIDASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50873">
        <property type="entry name" value="PEROXIDASE_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033016140" description="Plant heme peroxidase family profile domain-containing protein" evidence="4">
        <location>
            <begin position="34"/>
            <end position="1333"/>
        </location>
    </feature>
    <feature type="domain" description="Plant heme peroxidase family profile" evidence="5">
        <location>
            <begin position="179"/>
            <end position="528"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001970"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010609"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2441977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1333" mass="145347" checksum="B1BBBE0D90E25E22" modified="2021-09-29" version="1">MERISKGARLTLAAVALALLAASSLPGPRGVDAQSQQAIVSWNLVGSIKPEVAKSLNYDPTAKTVTTVSGAVVDVGAYLDRPFQCSGRVCANLSSAALDQGHLDMSDVSAKVLLWSPKLINVTAGREYDPRTKDWVSVVATCRELFQYEKRMASFFIRSSFHDSMAVDVSQCPGPNCGGAEASLLLSIEEMARPENAYDDFSLLAARAAKKIASFFDISVADTLAVCAAVAPEVLSKGRIKILTGSGPGVLRVGRLDSMMPSSPGNLPNTSVNLHEFAKFFKDRGMSEAEATALMGSHALIDTQACYNGRKINDYCNPATSDCTDVRMFRWENHYYKDICSPTLTITPIAPDELDPAETPILGMTQPEFDAEAKQEMCKFTSNEGRAMAMNNLAQVRRGNRSEAVVPPEPVVVTWTNKNCRAGSAYGINVTEQCPHAHLWFYTTTDAYLGQACQGVGSTPEAVGVRAAARSYINDQAAWDDTYRAAYIKMVSIFANWAPLADDSNPYYINGGECHSGSHLEAACAQATPGLATPDTKLLYSGEYSVLDATLGGSCGTCAQGICPLADQCGLCINYFNNRLVYLTTARNPLVTEANCCGCSTLIRSMTYNVSSDMVVSSTFVARWPDVVPTTQPAQPIPADLGGLVPDRGLDTTPFNDNLAPVLKVLNGSFPTPPLAPAGDLATICPAADGVYRVRGFPSSFHRWVPFQQPYANPPRAQIAASYAKPGTNLTVDAYEIDIYTAAKDIGCPAGKPTWVLTYNGSVPGPSFRVLKGRQTLVRFNNRLTPANLTGTPFTEFHPCEGGRSGRPISVHLHGSASLAPYDGWAEDTTCGAETKDYYYPNWRGGFGWYHDHQLDITSENAYFGLSGLYTTVDRAAEGGCGQPWNLDNIPEWDMQFKDAVLDSNCQLYYDRAGPHRNNLYGDINFVNGIPWPTVTMEPRWQRFRWLVSSVARPYKLRLVNGATGADVSGSICRVIGGEAGLRRAPVDFPAAGLFMGVAERYEVVCDFSSSVLSKNWNTNTLVTLYLVNTPDDRRMKDVPFFCNSHLVMKINVRCGMNSCPNKPPAFQPPAPGATVVTPIDRVLNQTDIDRALAMVSNKQCTRTFRFGRRHGHWVINGESWHTARIAAADVSHNTWEVWCLETGGGWFHPIHIHLVDFFVLARNWDTKQVHEYERNIGKDLVQLDPSAHIALLVRFGAHRGEYMFHCHNLMHEDFEMMRSLHVMPTPGSRTAGTALPMQSDQTIVTNLNYVYDLYADPVYPAAGPKPTSSLTPLRTPGAATAAALAMPIDRAIHRIYYPYGSTNITSGAGAKLADPVANPWLVPICKPQTAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TF06</accession>
    <name>A0A835TF06_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_011309</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000047">
        <property type="protein sequence ID" value="KAG2437046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TF06"/>
    <dbReference type="OrthoDB" id="511013at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004176">
        <property type="term" value="F:ATP-dependent peptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045037">
        <property type="term" value="P:protein import into chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000982">
        <property type="entry name" value="Inactive ATP-dependent zinc metalloprotease FTSHI 2 like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.720.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076:SF37">
        <property type="entry name" value="ATP-DEPENDENT ZINC METALLOPROTEASE FTSH 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23076">
        <property type="entry name" value="METALLOPROTEASE M41 FTSH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="343"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="domain" description="AAA+ ATPase" evidence="4">
        <location>
            <begin position="445"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="76"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="SMART" id="SM00382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2437046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="593" mass="64373" checksum="AF7CFF38A6346524" modified="2021-09-29" version="1">MAVAVLSGPTRAAHARDRTSAQPPAEALVHHRSAANPVLSDLAAASATAEPATATSSSGPSTTSATTSTSTSSSSSALSPVEAAYSAYLRRIAEAYLAEHPHLAGPEHAAHVARVVRSRALGTPLSFDELMRSAVPAPGDVPNRNSRGQVAEQVRAILDQYDREDFDLGIKQFMLEAKVKAKLEAASRGTSRDRAAPKDYEEALAAELFAAEEGAAPKEKAKTEDMVDDAFTTEVVEEAMALFGDANSVKTAWRTQEVLRELSYTQLWALVGEGHVARVRFYGPEKNKVMVTTRASAPGGERLCKVVLPPDPELLDHLVSNGVVVDTGVTEDDRLRAGLLVQMLRYTVPFMVISGLFWMIHTWILDPLPNKFRRQEFIRYRREMLHVASKLNFRTPAREVRIDTSGPDFIKWDDINGIDEVKKEINEIIEYLRNPALLRSRGVARIGGVLLAGAPGTGKTLLAKAIAAEGGVRMFTCSGTDFYDVYSGVGARRVRETFDRLRNAAPAILFIDEFDAMGAARGAQASGDESASIINELLVQMDGFEDNRGIVVLGATNRPGAIDSALIRPGRFDRIIYMPLPDALGRAKIMQAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TGV4</accession>
    <name>A0A835TGV4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_009366</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443298.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="541199at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="9">
        <location>
            <begin position="1759"/>
            <end position="2125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="299"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1494"/>
            <end position="1517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1543"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1978"/>
            <end position="1999"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1313"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1501"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1552"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1571"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1989"/>
            <end position="1999"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="1840"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="1840"/>
            <end position="1844"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1844"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1881"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1882"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1882"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1882"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="2031"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="2031"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="2082"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2443298.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2145" mass="221886" checksum="939514481B67F39B" modified="2021-09-29" version="1">MEADANRPLEAGTRHHLLHLTSTAASYCEMPAGGGGGGASCDLGRHSSSGRMLVDLDEAVAAAAAAAAAAASILAGSGRAQAAAGDAGGSAGGAGGCCGASYEAAGAAEADAGSGSGRGLISGTTEGDATTALGAPTTAVNSGVAGGCSAADYASLMESFMALKASYDVLLQQQDAMMDAEAAMEALSSPARPPVVLASGPSAMAAPAAAVAQAQTPAPQQTAMLKPQQLQQVVLQQQEAIQCRPISPTSSRRASLMSSAPTVVQGHAHRGMARRGSITGLMCLGLGAGGEGATAALSANSRVGSSQDDSSDQATQDAVGNCPMDGSGSGGDGGGDGASSVRGGSVVDAASIVLMDTGPSGAQCASPMSLLHKGLSSMASSGGVGELERLAAHARALKATCDVMQLQRDRAVHAATAQKATFDRALAAAQLEAEVVADSAAATKAQFDKFVLDKAEEKAAFDAVLEQTAAAAAQQKAIADKALVDFGELQANAVADKAVHDKALFDFQATAAADKAVHDKAMFDMQATAASTKAQFDKFVLDKAEEKAAFDAVLEHAEATAAQQKAIADKALVDYGELQATATANKAQFDKFVLDKAEEKAAFDAALEHAEATAAQQKAIADKALVDFGELQATAAADKAVHDKALFDMQATAASTKAQFDKFVLDKAEEKAAFDAALEHAEATAAQQKAIADKALVDFGELQATAAADKAVHDKALFDMQATAASTKAQFDKFVLDKAEEKAAFDAVLEHAEATAAQQKAIADKALVDFGELQATAASTKAQFDKFVLDKAEEKAAFDAVLEETAAQASQQKAIADKALVDFGELQATAAADKAVHDKALHDVQANAASTKAQFDKFVLDKAEEKAAFDAVLEHAEATAAQQKAIADKALVDYGELQATAASTKAQFDKFVLDKAEEKAAFDAVLEHAEATAAQQKAIADKALVDYGELQANAVADKAVHDKALFDFQATAAADKAVHDKALFDMQATAASTKAQFDKFVLDKAEEKAAFDAVLEETAAQASQQKAIADKALVDFGELQATAAADKAVHDKALHDVQANAASTKAQFDKFVLDKAEEKAAFDAVLEQTAAQASQQKAIADKALVDFGELQANAAADKAVHDKALFDVQATAASTKAQFDKFVLDKAEEKAAFDVALEHAEATAAQQKAIADKALVDYGELQATATADKAVRDKAIHDIQENAASTKAQFDKFVLDKAEEKAAFDHVLEQTAAQASQQKAIADKALVDYGELQANAAADKAEHDKALYDVQATAASTKAQFDKFVLDKAEEKAAFDHVLEHAEATAAQQKAIADKALVDMSELQQTADATKAQFDKLVADTAEEKAAFDVALVRAAEEAAEHQRRADTMRAEAEAAAARHASERQCMDDLQAQNERLLKQQEVLQAELAMALRSYTPRTIIDAGTPADKILAMMTDLLDGSPPTIQDILFVQSAILEAHDVYKPVNLGKQLLGSSALDKDVGLSLLQQLGGQDEADEATRAANGSASGGAAHHGAPGGVAGGGAGAALTLRDFGTRDAAMGRAVSAPQQPAGLSGSLSGGSCSSSLHGEEAGAGGGGAAAGGPQSAPAVSWDTLESALTAIMALGGPLEDNNNISNNNNTPTAAESSAAASGCVSRAGGCADGFALVSGSGAGSGPLGMAAPGTPRATALAAAAALQDGGAGRALMRAVSSASRSMHARARVGTVSAGQLSLCAAGGATGGATGGGTGGGGGGLVLGTPPLERTNTAASLATTVTELCELDEFPEQPLYTEVERVLSTGVGSWQWDAFKLADASADHALSTLGYFLFHQSDLIRKFDLRPQQLAAFLRRVEDGYRPNPYHSKTHAADVLQSLHVLIHRGGLAPGYVDPLSLLACYLAAIIHDYEHGGLTNDYLINSGDELALRYNDRAPLENHHCAAAFLLLRRPEYAFMAHLPKADTDRLRKMVIELVLATDMKQHFAIMSHFTTVHRLTSATSVTPSLMSGERRRSSSNASSVNSLACSGSGVELDKILIPLDENERILSLQMALKCSDIGHVCASLPVHLRWVAALEEEFFRQGDMEKAHALPVSPLFDRAKPGITKSQVGFFDIVVIPLLSNFSRVFTNTKPLLTYTMRNYKYWSEAQKTEQQVAAAAAAQAAAAAASGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TH76</accession>
    <name>A0A835TH76_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_010918</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000044">
        <property type="protein sequence ID" value="KAG2438216.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TH76"/>
    <dbReference type="OrthoDB" id="539773at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="74"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="107"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="164"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="200"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="227"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="253"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="276"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="312"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="350"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="376"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="403"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="193"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2438216.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="516" mass="51815" checksum="26AF35EA0A52037B" modified="2021-09-29" version="1">MLLQRSGVTSQLAASLEEGGRRDLNEPLLGSPARDASKAGGHGHGLVGLQRGGVGSLQPRAVGQLAVRLVRSRLGLQLLTVAACLSWMSASSWAILVNKHIMVNLKFAYPCTIAWMGLATTTLASLAALHAARLLPRHVRLELGFAPQHGGSSSSSSSSSSSGALAALAAGVGGVGGGAWGVGLLGVGRGVSWRYYATRVLPTGFFMALTFTTGNMGYLYLTVAFVQMLKAFCPVVTMLLLFVARLEAPSGRLCTAVGLIALGVALASYGELNLNLFGLTAMLVSVMAESVRLVLTQYLLAAGSAPLHPLEGLFLISSACTAVLAGQAALTEWPRLGAGGHLGLIRQHPGSFAAAACCGFLVNMLAITVIKLASSLTLKVLGTVKDAALVTIGIVFLKEHVTWLQLVGYSVSMVGFAAYNAIKAQQQQQQQHLGIGSSVGVAGGGGGGGGGGKDGAGTGGLGLGGSLGAGGGKGAGLGLGGPGAGGEVMVAGLVGGGKGNGLLLLPLYNGSDAKGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835THX8</accession>
    <name>A0A835THX8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">RNA helicase</fullName>
            <ecNumber evidence="2">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HYH02_010267</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the DEAD box helicase family. DEAH subfamily. PRP16 sub-subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000037">
        <property type="protein sequence ID" value="KAG2440689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd18791">
        <property type="entry name" value="SF2_C_RHA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000007">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000615">
        <property type="entry name" value="pre-mRNA-splicing factor ATP-dependent RNA helicase DEAH7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1080:FF:000018">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase prp16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF91">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR ATP-DEPENDENT RNA HELICASE PRP16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0347">Helicase</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="14">
        <location>
            <begin position="705"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="15">
        <location>
            <begin position="890"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="632"/>
            <end position="687"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1344"/>
            <end position="1398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="43"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="116"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="139"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="178"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="196"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="213"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="247"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="316"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="354"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="370"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="408"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="424"/>
            <end position="435"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="649"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1348"/>
            <end position="1371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00038040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG2440689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1398" mass="151905" checksum="B6BE4C1F82A153E6" modified="2021-09-29" version="1">MADRLDAPAEEAGGLMVRAERPVFKAPPPRTSILGLDKLAAQKRAEVAERESKRVKLSYEEDPDASNPQGAATAGSGGGGSSSTMPPPGGERRFRGQRTETPSHPGGVNSAALESLAEHKERQRQRERSGLYASTSAGADRDGGGRDRDGGGRDRDGRDGGRDHRDSRDRGGGGGSSSHKDEVLQRSDARFQQQLERYRQDRDRGGGGGGSSSRDRGRDDRGRDGSSSGGGRDSGRDYRGGSGSSGGRDRDPRDRDGGDRDRDRGRDYGGGGGGGRDSRDSRPGGASGSRRSEWDNTTPLRRGGGDDEWALTPVVPSGRPGDSRPTGPGSSRPGAPRSSHASGGWAAGGDTPLPAAAVPSGGAAVPSGRSGAGGGAAAGGGGFGRVQFDTAPSPALTPSWKSSSWNRQGGGPGGAGGGKGGRGPVERSPDLRPEGEEGPPGADGFDEVYAREKEDEERQMERDWYDQEEFGGGTDDHGTTRFVGDEALFERRTADLQRRVRKDGSTMSLAATRRANELDKAMNAWEENRLLTSGVVRLKEVSLDFNDEDEARVILLVHDTKPPFLEGKVVNNKQADIVLPLKDPTSDMAVIARKGSGLVKEVREKKEKNKSRQRFWEVAGSNMAKITGLTEEEAAAAAEAEAARKAEDGGDGEDGEDGEGGSYRKSNQFKSHLKKNEANSEFSRNKTLAQQRRSLPVYGVRDELLQVIRENQVVVVVGETGSGKTTQMTQYLHEDGYTKYGTIGCTQPRRVAAMSVAKRVSEEMGVELGDQVGYSIRFEDCTSDKTIIKYMTDGVLLRETLINEDVDSYSVVVMDEAHERSLNTDVLFGILKRVVTRRRDFKLIVTSATLDAQKFSDFFGSVPIFTIPGRTFPVDVLWSRTVQEDYVEAAVKQAVTIHLRDPPGDILIFMTGQEEIEATCFSLAERLEHMRGNGSEIPELLILPIYSQLPSDLQAKIFDKAEEGVRKVIVSTNIAETSLTVDGILYVIDTGYVKMKVYNPKMGMDALQVFPISQAAAGQRSGRAGRTGPGTCYRLYTESAFRHEMLTMNVPEIQRTNLANVVLLLKSLKVNDLLEFGFMDPPPRDNIVNSMYNLWTLGALDNTGALTHLGRQMVEFPLDPPLAKMLLMGAQLGCSNEVLTVVSMLSVPPVFFRPPDRAEESDAAREKFFVPESDHLTLLHVYNQWKNNGYRGDWCDRHYLQSKGLRKAKEVRQQLADIMQQCGLQLTSAGSDWDVVRKAICSAYFQNAGKFKSVGEYVNARTGMPCHLHPSSALYGLGYTPDYIVYHELVFTTKEYMQCVTAVEPEWLAELGPMFFSVKEVGGSLLESKRKQRADKEAMAAEMAAAKAKKEAEEAERARATEALRSRERDAIATPGLGPGPGRKGTTPALSKRRPMGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VRD1</accession>
    <name>A0A835VRD1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000196">
        <property type="protein sequence ID" value="KAG2422714.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VRD1"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="197"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="363"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="397"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="19"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="59"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="219"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="397"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="419"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="459"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="499"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="539"/>
            <end position="563"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2422714.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="563" mass="54305" checksum="18A4FC96EB25FB07" modified="2021-09-29" version="1">MREQTPAATIPRRPPTRPPVEAASAVSASAAAPAAARVSGGCQQTPAATIPRRPPTRPPVEAASAVSASAAAPAAARVSGGCQQTPAATIPRRPPTRPPVEAASAVSASAAAPAAARVSGGCQQTPAATIPRRPPTWPPVEAASAVSASAAAPAAARVSGGCQTRLAATIPRRPPTRPPVEAASAVSASAAAPAAARVSGGCQQTPAATIPRRPPTRPPVEAASAVSASAAAPAAARVSGGCQQTPAATIPRRPPTRPPVEAASAVSASAAAPAAARVSGGCQTRLAATILRRPPTRPPVEAASAVSASAAAPAAARVSGGCQTRLAATILRRPLKWPPVEAASAVSASAAAPAAARVSGGCQQTPAATIPRRPPTWPPVEAASAVSASAAAPAAARVSGGCQQTPAATIPRRPPTRPPVEAASTVSASAAAPAAARVSGGCQQTPAATIPRRPPTRPPVEAASAVSASAAAPAAARVSGGCQQTPAATIPRRPPTRPPVEAASAVSASAAAPAAARVSGGCQQTPAATIPRRPPTWPPVEAASAVSASAAAPAAARVSGGCQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VXP7</accession>
    <name>A0A835VXP7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein DETOXIFICATION</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Multidrug and toxic compound extrusion protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_014213</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the multi antimicrobial extrusion (MATE) (TC 2.A.66.1) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000089">
        <property type="protein sequence ID" value="KAG2428891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VXP7"/>
    <dbReference type="OrthoDB" id="2126698at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015297">
        <property type="term" value="F:antiporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042910">
        <property type="term" value="F:xenobiotic transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044644">
        <property type="entry name" value="DinF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002528">
        <property type="entry name" value="MATE_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893:SF46">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42893">
        <property type="entry name" value="PROTEIN DETOXIFICATION 44, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01554">
        <property type="entry name" value="MatE"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="326"/>
            <end position="346"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="480"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="511"/>
            <end position="535"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="556"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="592"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="622"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="686"/>
            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="40"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="64"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU004914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2428891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="724" mass="69923" checksum="B99005275A99BE8D" modified="2021-09-29" version="1">MIARHQLSVRCSPGVARERPSAGSRLVPARSGIRRPIFQSAASSSNAASAGSSSDGPAPGGAQNGPQQQQPAIPSAKPAPPQVPAPAPQHLHKHHHHQSPYPDQAALDSEILSIALPMLATLAADPIAGLVDSAYMGRAGAAQLAAVGVALSVFNTCTKVLNVPLLAVTTSSVAKATGEAKRAAEAAAEAAATAMAASEEVAAAAQATATRPASSAASATAATAAAGGGGTPAAAQVVTLDPAAPAAATPAATAAAAAAAAAASAAAAAAEAAGEAQARAATSCLWLAAGLGAVQAAALLGGAGWLVGTWGVSAASKVYEPALGFLTVRAAGAPITILMLTLQGVYRGLQDTRTPFQATLVSNALNIALAPILIFGAGWGAAGAAAATVAAQAVPVALMVRELLKSRKLRPFGFAGGGGARSGSSATVAAAAAAAGSAEAAAAAAGAGGGGGGGEAAGGGRGLLGAVADMMELFKPTGYLVLRSASVTATYAVATALVARAGAAVTASHQIAFQLWLACGLLADALAVAAQSLMARDLGAGSAAGARQVAGRVGGLSLGLGLALAGLMAAAGQLGLPAAFSSDPEVLRLVSNLFPLLAISQPITVLAMAWDGVLYGAGGFRYAAISMALAAAPAIAVMYGGGGAVQEIFRMMGGYFGGSGGGGAAATATAVGAAAAGLSGEEQLGVVWAGLGVLMLMRWLTIWVPYKLRAGPFAKLQGEERGGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VXQ9</accession>
    <name>A0A835VXQ9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_014043</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000085">
        <property type="protein sequence ID" value="KAG2429464.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VXQ9"/>
    <dbReference type="OrthoDB" id="543478at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000390">
        <property type="term" value="P:spliceosomal complex disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052094">
        <property type="entry name" value="Pre-mRNA-splicing_ERAD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44313:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY C MEMBER 17"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0143">Chaperone</keyword>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032394159" description="J domain-containing protein" evidence="6">
        <location>
            <begin position="26"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="domain" description="J" evidence="7">
        <location>
            <begin position="38"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2429464.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="82" mass="8655" checksum="12DC8DEAED743CDB" modified="2021-09-29" version="1">MASRCILLLGLLLLLLVAEKGGVQAGSKITAADLANLNLYKVLGVTAKSTSAEIAKAYRKLAIKYHPDKNPKPSAPITVLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VYT8</accession>
    <name>A0A835VYT8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_013858</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000081">
        <property type="protein sequence ID" value="KAG2430031.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VYT8"/>
    <dbReference type="OrthoDB" id="6275295at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12446">
        <property type="entry name" value="RRM_RBM25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034268">
        <property type="entry name" value="RBM25_RRM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053294">
        <property type="entry name" value="RBM_PWI_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47334:SF2">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 25"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47334">
        <property type="entry name" value="SPLICING FACTOR PWI DOMAIN-CONTAINING PROTEIN / RNA RECOGNITION MOTIF (RRM)-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="3">
        <location>
            <begin position="107"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="219"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="294"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="308"/>
            <end position="349"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2430031.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="371" mass="39125" checksum="6ADDB4F1A872C159" modified="2021-09-29" version="1">MSGPPGFPPFGGFRPGMPPGGMGFPGQPPPFGMRPPMLMGGMPGMPGMPGGMPGGMGNLPGLRPPPPGMPGMPGGMPPGPPGRPGIGGTSALAKSVYVPPSIAEKSTTVYVGKIAASVPDDVVRTLLDACGRVKSWKRQMDPDTKQPKGFGFCEFEDAEGVLRAMRLLNGLKLDGSELLLKCNAATQKYTEQYEAQKNAEKAERKAKAAADKAAAAAAGEGAEGGAAAGADGKEEGEDGEADEDAAADNRVLEVVMTVVSEREEKTRGALPPPPPLSGGGSAAQAANEFLAQLGGAGAGAPGSGGKGSGRERERDRESERERERERDREREWAREAEVERRKDDERRRELDVKYEARLREWERYERCVMAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VZ52</accession>
    <name>A0A835VZ52_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_013526</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000076">
        <property type="protein sequence ID" value="KAG2430994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VZ52"/>
    <dbReference type="OrthoDB" id="194358at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010730">
        <property type="entry name" value="HET"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06985">
        <property type="entry name" value="HET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Heterokaryon incompatibility" evidence="2">
        <location>
            <begin position="49"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="802"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="886"/>
            <end position="908"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="710"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="723"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="736"/>
            <end position="750"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="766"/>
            <end position="787"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF06985"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2430994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="908" mass="96661" checksum="17BF148F22EAE33E" modified="2021-09-29" version="1">MPRYLRVKDIPDILTELKAGDASSTPYQLDEWQKRWCHVTDTIEEDAAVLSYRWRIRGHSENIKDYRTWLKDCRSEGYQVAELRDGQRPVRWELADGHALQIEVAAWLLFLHTNSVAEYAWVDQMCVPQDASVDEKMGHIKDSPAIYAAGKVYVLLAPVVDYATGRIMTAKDARELVKSFRSEMNNYRGYDFLSRSAVKCLLVNHSYMRRVWTIQEAVAASRPRMWPLLGEGELNSYQSLYVVDWPEFNAWNGHPELGPIYTRLFDKDAEGEAVRDYYDGDYTGAIRVLREHASYAIGYLAMMAKDLMWITQDRNGFTNDIKRATSAARRAYVLLNHQQVHAARSFLPEDRVLALVPLVDYGAWKSATAGVPGHHLVQASVAWAYGVMEGEMQTWKWSMRVYNSTACSARGLELLQPRRNLGDTTSMHGASPRWEQALPPGGSALTLPLPQPHPTPKVASYLAASGALGPEAAAAAAADGAGGAALARCLRAGSGEGDGDDRSGRLLPAAVPVAGPLALHVELSVVMPHPGNPKYWGGGPWTGVRDALGTDEGFRLAVQWSLEPWRDPTKEFDIDRCAVYVVVSSSCGAEGGVGTEGGGTEGGGGGRLRHPCILVIAIPSGEKPPRSGQVMTVLEVARPLLQPLLDCLKRQALSHITEPLTALSGGVDEPAAAAAASAPSAAQAAAAKAKLHTAAAFTAAKAAVAMQGLAKEEQDQEEGKGAEGLSGSSIGSSSSGEDEEGKAAEMEVEVEAPAQEQEPAEEQEQEPAKEEEQAEEARAEEPGERTPAEGQKQVQATEEEDGAAAAANGLPFTGALEAAEEGAPANTTTAPVAAAATAQLLSDAPMAAVAPAAGTAIQKGPAAGGGGEGGEAALLPFSGVETAAGAKYAGQQPAPVKQEDAGCCCTIS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VZU6</accession>
    <name>A0A835VZU6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013468</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000075">
        <property type="protein sequence ID" value="KAG2431036.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VZU6"/>
    <dbReference type="OrthoDB" id="342190at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37807">
        <property type="entry name" value="OS07G0160300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37807:SF3">
        <property type="entry name" value="OS07G0160300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13671">
        <property type="entry name" value="AAA_33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="104"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="152"/>
            <end position="199"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2431036.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="326" mass="33681" checksum="A3A7EA5A796B1971" modified="2021-09-29" version="1">MEFLILMKGLPGSGKSTLAAELARELRCPLIDKDDARDVFQPVVPQAPDLDWNGLSYDVMFRLVERQLGLGLSVVADCPFARASLYQRALEVADKVERKLRCVPAASDSSPEIEGPARSQQPSSAVMSSAVLPTAAAAAAAAAAAAAAAPTAGPAACGRPGLPDGGQEPRGQQPGTSGPAPDAGGLAPEAAGSLHPSPAVAVATASPASAALADSSGAPQAPRRLAVVVVVVDVECRDEGLWRRRLEARGAEDAGTERSHKPGSWEQLQGIVQRYGDSWRWSTDGSAHVPYHVAVDTAAASTAECVAAVLCYLQALKNQVSGRPTR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VZV2</accession>
    <name>A0A835VZV2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013070</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000069">
        <property type="protein sequence ID" value="KAG2431998.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552533at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031490">
        <property type="term" value="F:chromatin DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044661">
        <property type="entry name" value="MED15a/b/c-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33137:SF43">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33137">
        <property type="entry name" value="MEDIATOR OF RNA POLYMERASE II TRANSCRIPTION SUBUNIT 15A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="177"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="422"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="709"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="777"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1011"/>
            <end position="1035"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1258"/>
            <end position="1318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1372"/>
            <end position="1433"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1497"/>
            <end position="1554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1606"/>
            <end position="1785"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1862"/>
            <end position="1914"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2074"/>
            <end position="2100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="193"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="220"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="235"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="379"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="380"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="422"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="777"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="799"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="826"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="906"/>
            <end position="930"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1260"/>
            <end position="1269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1294"/>
            <end position="1306"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1606"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1659"/>
            <end position="1673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1697"/>
            <end position="1713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1767"/>
            <end position="1780"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1885"/>
            <end position="1903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="2087"/>
            <end position="2100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2431998.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2158" mass="209246" checksum="81D679402AB4A2EE" modified="2021-09-29" version="1">MCRKDLLVVEPSGKAAMSLADFLQAAGAVLGGQQLAGRLLRVLWWDEADDNGSYTPRWFQAEITKYDSKTGRHSIRYKSKELADEKPHEHLYLPLTLHHMNRYAPDAIDAFQTAEPWQASPLKQQPHGLPDHGPAATNTATNATAAAGLATAAVGGAAGASGRERVPRELLRLLDRVADPAEPTTMPGDGARAATSASADTPVASSAPPASLLAAAGRGSRGRGRPRGRGRGRGRSAAGASSSRPEAGRSPAGAAAAAGRGIELLVLVGRGRGRGRGRGRGLGLGRGRGLLGAGSTGAGAADAQMEAEADAASQQQLATAAIGRAAAADGSVVATAAAADAPGSGAMLVGGDAADVADPTSGGGSGSTRGGGRGGGGLRGRGRGRGRGRGRGRGVVGTAAGVLVSHVQVAALKVMQKYVRGGARGARGGGGHGSRGGRGSRELKNLLTPHLPGRPTRTLSAGAGAAGQTSAGSGSTSATAAAGRRKPAGIAGAAPSSAAAGGAAGGVASAAQKRVVEPPALPPLPVPSAAEVAARLAYYRKEAARPLVDIRSPALRGEQEVVGRQLPATRKTKPLLELTESMPTTKRGKVAHPLNQLRKGLRRSSNPAPGALAPPLESLAAKAGIGSAAAPQKSGKAAASRPVKSEVAAAGGGKLGAPTLAPAAVVASAKGTAAAAAEDKTRPAEAGAAAKRPSQAAAAAIGAAAAKPRPGALAEAKEGSGTGTKAAPGAGPSGRKRPAHEAGIDAAAIVSAVQKQAKTADGDAAAAAQAAAKSPAAGSAAAKEGAATDNAAAAAAPPGAAPAPPPSPPPPVKRGPGRPPKRKPEATPAAGAASATSPPGSAPPASAAAAGAAGSSPAAAPGVAAAAAGMKQPAAPPASAPDKTKRRSRELASLLSKQARARIGKRPSVAAAAAATAASGDAAGPSAGGVAAAKAQAGAARTTPANRLAASMAEAGTLGLIVSPGRRAAATAAAKAITAAAELELPKPRGSARTGKTLRVERLRQVGVSPKGVAGRLAGSPGPPGVRGRKPGAASAPASAAKGLAAAKGLAAAKGLAAAKGLAVTKGLAAAKGLAAAKGLAATKGLAAAKGLAAAKGLAAAKGLAAAKATAATKATAAKPGRALMPAAGPGGTTAATGSGGAAAAAAGATPEATLATSLLRLSAATGAFHAAALALPGIPPAARPAATTEDPVLGPLVAAMQSGTPQERLVLLVRLQELVSSTAGSLATAALRPPVSGGRSQLMLLPASQDAAMAAAGAGVDGTGGGHAAAGVAATDSQRRAKTQSEASKRPSARAAGNGPSAAAAQEDDRAAASTLAAASQDARRAAGEAAVAADEAAAAAAATGTVAATAAAAEPDALGANASTAAAAATEAVPVGSKRQQSQGRTPSKRPRASGDAAAQPTPSETEGSICRRGGSTANVAAGDTTAAPDTRGVGFRAAAATSLEAQDEGFQASMQEAAADLAAAQGGLDPTSPHALRKLASAALHIQEAEAHAEAAAQEAHAEAAAQEAHAEAAAQEAHAEAAAQEAAEAGAEGPVAAAPQPSARPSASARPAALVQDGAVITSTVLANAIAAATAAAAAVHNGMPQAVTAVLGSGDAAALPLPLPVPDQPPPLANSTALQEPEPGGLQPRRTRPVAPARPPSLGARTAAGDPERTVTVAPPGVAAVPATSESTGRRATPSLPAATARQSQLQSPQGAAPRRGRRPASAQTSVDGTARDGGMDEVAGGSRPLPVPPLVGLEAPAPLQPNALRGLLPPLQAPFPQQQQHQQQQQQQQQPDDASSVIVMQQLQLRLQLQQQLYGAGGHDAGGGAPFLAGGRGGARAAAAAAAAGGAGLLPGMEMQLGNGALYDTLGLLPQQQQFQPPPEPPRRRGRPPRSTYAQQQQQQQQQQQQQQQLLQQAPPPHMAYIGTADGQGFQLDVGGTLQAVGGGYGAAVVPPGLGLPGPYLNLIPLARGGSGAGAGAGACGFALAGGGGAGGAGYGLYGDGYRGTYRHELDLTEPDYTPLAPYGPGLVGSGYGPLGFPAPRDSGPYPRGVRGVAPPLDDLYSTQSVADITATLGHYQATGMLLGGGRGGTGPQRQGGQRGYGASGSGGVGPQVSASAQLQLLLASQQAAEDGGGLLAQAAAAQGVEGGPARRASMPGGVDLGADYRGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W1A9</accession>
    <name>A0A835W1A9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_013001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000067">
        <property type="protein sequence ID" value="KAG2432431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="548503at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615:SF66">
        <property type="entry name" value="CARD DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45615">
        <property type="entry name" value="MYOSIN HEAVY CHAIN, NON-MUSCLE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="16"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="448"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="736"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="784"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1339"/>
            <end position="1369"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="535"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1183"/>
            <end position="1217"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1257"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1375"/>
            <end position="1480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="86"/>
            <end position="97"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="108"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="143"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="174"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="218"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="229"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="269"/>
            <end position="294"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="295"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="316"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="340"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="357"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="457"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="475"/>
            <end position="487"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="488"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="513"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="753"/>
            <end position="764"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2432431.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1517" mass="152755" checksum="3F03862AE27CF1B7" modified="2021-09-29" version="1">MRKQTQLADLIASSGLVSGISKRTSSQDGSGAGGLPPPPPPSQPVLYGFGPGSGSKDRPPLPSGAASSPGPGRPPRAGGGGGGGPATSSSPTPPGSRGSVGSGGLMESHSQGQGQLNSHPISPSPLPGHQLPGQHAHSFLGGHQHHQHHHHHQHHQQQPQQQLPGYQSQGGGTPTRSAPSGSADSFFHDGPSSAPSLPPYLGSGFLPPASGGPYDLTGGTQYESETYASQPQAQSTEQPQQPQQPSNSDLGYVFSSSTVDVAGNGGAGAWAAAAGSRAGSRDAGGTRTAPAGATRGKGAGGGGPGAGPRRGGGGAPQPSVQQQQQQQQQARPGSGSRSSTAPLNRSASDSALRMANAAPGGTAAASSLTGSGTAAAPGSATRPGGSVDAAWVESGASGSQQDMLEPSSSVPLSGSGGPGGLLPVIGSRNAGRTLGVAAAAGAELVVVEEESSEFASPIQQPANVRSSLSQPQAQGLGGVGPGAGAGPSTGSAASPSGASRSVGPLSGGGAGVGPASLSTGAPAVAAAPAGPSAEVLELRRMVAELNAQVTRLTTQLRDNEAAAASQLQALVAAAAVSGREAAEAEAAKKHMKALKSAEAARDKAEVARRSAEKRAKSAEDELAVVKDKLDAKTKQAAELEAAVVAAQSALERQRKGHEEALAALEAQHKLQSRKIASDADTEKKSAQENLAKLQADMAKRNQTLLALQADLEMASRESARRSEQVAALEESVAKLQSELDHERQHSRGRGRGRHADEGSEEGHWQTHSIAVEEMVLKSPLRGDTVATAASPSGKTAGIETPHGGATSSPARGRPGALSGVASATSLSASVSVSGANAGGGGGGRSAAAATTSALLDEQTKAVRKLQTEVATIREGYAHRLVALEEVVAGCEAAMRDGLQGIERLFGVIVSRTAGLLANRLGGGTLALPSGSRPVTPAAARAAAAVAAAGGAGGAATAVLMQMNERLAAENAQLLAELARWQSGRHGMLRKMNMTVLGAEPPPPPSEKPLTHEQKIAQALAAVTGGARGGAAGQARQSASGANFPGSSAGSFNGGAGDGGGGGSAASAFTPGGVAGASGASAQQTAAREALAAAAREVLLAGRKELLPAVMTAEGWGEGAAPGGLDAGAASAALHGGKAEAALMTAESVLRLRTQVLALQAEVARIRASGGEVVERGRDTAVLQEAHEAAMSEMRRDLASARAQLSHLQRELERARAGIIDARPAGSGAGGCDAAERERLESAAAAAREEAGRNRSLLAAAKRDLEARERQVEEAAVRFERLESQLREARGESSRQAEGIKRLRLLLAQAKVMLREQAGVAFMEDDPGLELLLAAEKDKTIKGGGGGKGGLPPRPGTSSGHRASDGDGPLFKAMDAREREKEMQRLTNELTDAQSQLATANKELKKARKQLTTQQEAAAAAEKEQRLALASTIDALAKDAAAAKDAGKTLQKQLQEAQHDAGDLRRQIADLKDKLARAKLDGDYLRARAAAGKIKPKLSHARALSINIAAATAVPSEG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W3D2</accession>
    <name>A0A835W3D2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_006604</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000041">
        <property type="protein sequence ID" value="KAG2439077.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="537063at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="139"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2439077.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1709" mass="186469" checksum="9F871DC9B3576246" modified="2021-09-29" version="1">MIATPDGFVHASVAGSADLICVRDGSDCQEKDPYLFPTLHTSCHDADGCHAGWTWDAALAHCVDVDECAPGSPYNRCGDVAECINIVGNHVCVCPQLQDTYGGTYEGRYRFDRESQRCIDDTASPPCVWPQFRFGGQCVDDPCQFKPCGEHERCISAPDGTDYFCACKGRRVDGVCKLSPCLTSPCPEPWATCYNNDDWRGRRCAGSSCDGVECDDGEHCNSGVCVPDSDKSCNLPESWCDGDGEILAKADCGDGDGIDDWACFAPSTGRRAVLLSSNCSAGTDYWPDAPKALCPPLFNNLTCPLPWDEWCTDPGYVRRKLDCGDGDGIDDWTCTRPALGQRGVLLSSDCDAGDRWPEADVALCPPLFNRTICPLPSDDWCRGEGLLQEQLDCGDGDAVPDWVCHHNVTFQRKVLLSSNCSTDHWPQADTSLCPPRFASMPCPQPDNWCDGAGEVSELSNCGDGDSIGDWTCIAANTSRRAVLLSTTNCTLDYWPEAPKSMCPPRFNALMCPLPWDDWCVGDNLVRSKVNCGDDPSTLDWVCVKTNTSGRGVLLSTNCSESHWPDADKSLCPAAFSDLMCPLPWDDWCVGDNLVRSKVNCGDGDAILDWACVQTNTSWRGVLLSSSDCADSHWPDAEKSLCPTAFNGLMCPLPGEEWCTGPGDVREKVDCGDGDAILDWACVQTNTSWRGVLLSSSDCADSHWPDAEKSLCPTAFDGLMCPLPGEEWCTGPGDVREKVDCGDDSGVLDWVCTHPANGQRGVLLSSSDCSDSHWPYANKTLCPARFSDAPCPVPGGWCEASEGEVLHSLDCGDGDGVGDWACVHTDTSRRAVLLSSGSCNTDDAGWPTAVRSMCPPLLNGMMCPLPYGWCEAGDGAVAVVLQRVNCGDGDGIDDWVCSQPATGQRKVLLSSSNCSVDYWPQADAALCPPVFNRSMCAMPYNWWCSGDGFVLEQLDCGDGDSVDDWVCIHTPTGQRKVLLSSSNCSVDYWPTADRSLCPNRFNSAVCPMPYDWWCSGDGLVLEKTDCGDGDAVDDWVCVRNETGQRKVLLSSSNCSVDYWPQAERSLCPKRFNSSMCPMPYDWWCSGDGYVLERTDCGDGDGVLDWTCIHTPTGQRKVLLSSGNCSVDYWPQADKSLCPARFNQALCPMPYTWWCSGDGFELKATDCGDGDGINDWVCVHNATGQRKVLLSSSNCSVDYWPTADKSLCPPVFNQAVCPMPYGWWCAQAGGDVLEQLDCDLDGVPDWLCTNPDSWMRKVLLSSDPSNCTQDYGPAAPRSLCPSRLSKAMCYWPWGDSCSGESYTRQRADCGDGDGIDDWTCVQHNSSYRGVLLSSSACDDSHWRDADKSLCMPVFKDLPCALPWDGWCVGENLVRAQADCGDGDAILDWMCIETNTSRRGVLLSSNCTVDHWGDPDKSLCPAKFQDMMCPLPYYWCDQPGEVLERVPDYCGDGDAIPDWVCTNPTTGQRKLLLSSSDCSNDHAPQADTSLCPARWNGTVCPQPDWWCTDTGEHLERVDCGDGDGVDDWVCLNPSTGQRRVLLSSRCTLSGATEDFWPQADKSLCPNRFNSEPCPQPNYWCSGEGMHIEQLDCGDGDSVPDWVCLHNATGQRAVLLSSGNCSTDYWPQADKSLCPKRFDSLPCPQPYYWCTDSTLTLESVDCADGDSVPDWTCIQNTTNQRAVLLSSGNCSVDYWDTAPISLCPTRFASEYAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W3D6</accession>
    <name>A0A835W3D6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_006617</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000041">
        <property type="protein sequence ID" value="KAG2439092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W3D6"/>
    <dbReference type="OrthoDB" id="550561at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
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        <source>
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    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
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    </evidence>
    <sequence length="1091" mass="108904" checksum="4957E490E0A55D66" modified="2021-09-29" version="1">MARTKLKVKQQAAARRQGTAAAAQAGAEEPAESAAPPAAAPEPRPPARRGRARKDAQAVPATAAAPALAASGQRGTREAAKAQRAKRAEERAPGLELLGLVSEVLDAGAAQAPEKRRHNKSEARDTGEGPKPARHTAGKHNKYGEGAVSVKAVGGVKAGAGKAAAASKTAAAPAPATMSGLDALLGPGGGDSGGGSAGASIAAAAEGGSGLVRLGGLTKGKVKFRGSVAAAAPAPLPTAACTAGATTAGTAAAITSAKAAKAPAAKASVAAGGSRRKAASPQPQVKPDGLDHVRAGDGAQPEHQEKEEQQRTPDRKQQKRSADAKLTARPGKRARAVEAEEQEQEDAKAGPALAGAPAGRGGGAARREKGARAADAADAVGEGPSVLNAMAAAGNVQGGSDVEAARDAVQPAAAAAEAVGPGPSSAPAATDGAPAGAAGVADVAAATAPYDGDGMVEEMGPEEDEEDAAEDGVEGGAAAAAAAAAAASKRRKVTFSPNAQATDGAGGLIRFRPVLGARAGRGRGGATTPGRGGGSSEARGQDNPSAAGDGDGASGAPAATGSAGARARPAAQGGDKGERADGDCAAAGERRKQEEGERDAEEEEGGGRDLARPRAWGASARKLHWTDERLGYLYDVAKGNVESGAKPDWEAMLTKMGWNAFPDRTFALTKLRNRYNEYRRAVEAGGTSREPRVAPRKPYPYPLQFKVREVLSCLPGQKGTLKEVWVAVAADPLFRLALDHQPERPAGAALWQKQVSRVLNSGSNYGFVDTGERRQGLIVYTYDPEHDFTKGRGVEQYIKHQKHPAISAAGAGTGAAGAAAAPAVGGGAAALLVGIGPGVAVANAAAAPIPPLPQQHPPRSGGQEPQQPEQRGQPSEAERSDTAAGSTQHGAGTGAGTAGEVVDLEEVRERWKIVMWDCRGSRPKTRAKQAGAPQAAAAAAAAAGGSSGGQRAEDEQEPGTDGTDAETATEDAATETDGEEGQRARTRARGRTSSKSSAGGASKQRAGGKAGRPDGGGGGGGGTGGAKPAPSRKRRQHTPQPRRWKDGGRADEAALAAAAAAAALAALESGSAELSEQELMAAAMSMAGMGF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
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    <name>A0A835W4F3_9CHLO</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">HYH02_010777</name>
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        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
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            <taxon>Viridiplantae</taxon>
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            <taxon>Chlorophyceae</taxon>
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            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
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    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000042">
        <property type="protein sequence ID" value="KAG2438985.1"/>
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            <begin position="74"/>
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            <begin position="78"/>
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    <evidence type="ECO:0000256" key="1">
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="EMBL" id="KAG2438985.1"/>
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    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
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    </evidence>
    <sequence length="173" mass="17859" checksum="299CE5D92BC05EF6" modified="2021-09-29" version="1">MVVAGSERLSAAQAVEVAASLGRLHLEDQMVLDSLGRNLVSRLHELSGSQLADLVEAYAHSNATPGKVLADAVHQRLQGGGSSGAGDGSQQRMEVDESRVAVGRATADGVQLGTPERGGEAVEGRGEVQGEDAARVRRGLARLGYGAPADAADNSGTKQRQGQSDRSQGLDYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W4G5</accession>
    <name>A0A835W4G5_9CHLO</name>
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        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
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        <name evidence="2" type="ORF">HYH02_011801</name>
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        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
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                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
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        <source>
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        </source>
    </evidence>
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        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
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    </evidence>
    <sequence length="357" mass="35881" checksum="1664DE8F828EADE8" modified="2021-09-29" version="1">MDFKDQGPHSGQGALAQLAQNKGAGPNVVAKARGRVAPMLAYLHEHGVASPQEPAPGASVADWQAWAMRVFDEVDQVKEQLRRVQRQEEARRRREQRQEEARRRREEKARLREDVLRSILAEAAPSRSGSQVSAAALVLAATFTPATSSAAPSAPESGSGPVSGSGAGTGPSGSGGGPSSQQQQQQEAGEAALAEGAGAGVGTGPSGSGGGPSSQQQQQQEAGEAALAEGAGAGVGMGPSGSDGGPSSQQQQQQEAGGAALAEGAGAGVGMGPSGSDRGPLRQQEAGGGLGPWAPMLAAPVASTLQATAVPALAGATVPTVQDPRITLPSLSEAPGCCRCLPWLRAPRARRNLLVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W5J3</accession>
    <name>A0A835W5J3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
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        <name evidence="4" type="ORF">HYH02_009977</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
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        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
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        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000035">
        <property type="protein sequence ID" value="KAG2441387.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
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    </dbReference>
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    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
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        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
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        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050167">
        <property type="entry name" value="Ser_Thr_protein_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257">
        <property type="entry name" value="SERINE-THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23257:SF958">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE WNK4"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Pkinase"/>
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    </dbReference>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        </location>
    </feature>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1785"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1989"/>
            <end position="2008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="544"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="815"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="856"/>
            <end position="877"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1131"/>
            <end position="1176"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1405"/>
            <end position="1431"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1442"/>
            <end position="1471"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1509"/>
            <end position="1523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1600"/>
            <end position="1618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1640"/>
            <end position="1650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1651"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1785"/>
            <end position="1803"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1821"/>
            <end position="1832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1833"/>
            <end position="1853"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1921"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2441387.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2365" mass="234871" checksum="10531A882D095880" modified="2021-09-29" version="1">MKSCLTRRRVLALLCYFTFIQCVHISAEILLADLPVDRGDAAGLATLRLPVGISTALSDVVEVPAGERLVLVGEGPERSVLDLRAWGPTAGTPAFHLLSGGSSLELHNLTLLLPLLPEAAAAAAAGALPPSVLSHVVVAAGGNSSNSISTTDRIQVVLKGATLVAGSCSNLAVHRSSFCRNLNGWRARVAAYDEPTILGGTVRYGSRAPGGGLMALGLSAAGGGSGSGDSPALAQLLDCTVTCDAGIISDGGGAVAMPYVPSGPTGPWDCVAVTVSDSAGLAALPELVAQQLAPAGATVLVAVEAGPPVRVDPGKWTAIKIRQQTSVFFIGRGRAQSLLDLAGLPSKQFADVSSDVVSQGRLGLMDMTLAGLSYPARALTRKDLMAAWVHAVGISGVQEPSLYVHTTGRIAPPEVMAWIKNVRLALPDAEAQWWRNAAPVEAGGTGLPLLSSEWSGFGLGGPNTLLDAWVYGAFPPAAPPGARGADPAHQEWETGPVRMHWLGLRACDYCWFAPLSRCIPMASSLGSGGSSSSNASPPAPAPAPATATAPARARARAPAAVDVASGVSSGVGSSVSTGGEDLAAGGVDGVQTATTVDVQQDGATAGGAGFAVAVLAAPSPPPPSPPPVVQTTWPLADTLGTDVAVKLPMSRVALIVGIRGTPYAELASLCGGGGGGGGGASDDPAAGAGPMYIMPPADYESVASMFGGSASYTRRLRRSSGLGVSLMPPAGDYWDVAVRGEANPRMTLGGSGGGGSGARCVLTSPPAVQSAPGPATWDMMDLSDRIRIRVGPAGSDADGPSLQIQGFTLYNLAPYRPPPPPDPPLPPPPPDRPGINLGEVIAIEINGQPVDSQGRVVTGPVGSSSSGGDAAATTSASTDGAAAGGAAVSISSGGVAVSANDSAASAAVYGGEASSFTGTSTTTGAGSSSSSSSSSSSSSSSSSSSSSSSSSSSSSTSDSGGASAAAATSLAISDTSASDGTSVAAGGGLGTAASTAGAADALAGGGAGVAVDGAALSSPAGSDLNPVRDVTGGSDGGSGAAGTALDVAVGGEEVGGVAGVNGGDGFTNAVGETGGVTGGVAIGEVIGVVVDTGGGGDTTGGGGTTGDGGAATGGWTGGGGGICWTCLLRPTQPPQMPSPPSAPPAPPQPPVPPPEPPLLPPSPPPSRPPPPPPDPSDPFHGLSLALPFFQFDRFSPLLFAPAVGQPSPQPRRRLPPLALVNCTLVVPPPELELLRRLLLEAGRLLPGSGGTVGAAGLGRRRRRARRALLSVSRGRDSRSGRVLQQQSATSNNSSSSVDDAWPWAQPAWPAGVPLASGPEVPLPSQLVACPRSLLLSYAAVAEVSEASATAISFRRISFLGWSGRDVVVTSQLPDDAPTGLIPDLWMDLWKAERLFYSPLLEASCAPPPPVPPSPPSAPPAPQLEPPQPPPLSSGTGGGAGGSRLPDAARGPRGGTTTLTPAAPPVGATSTPPAAAAAAAAGAAAGGGAGAGGAATTGAGPADVQASGISAGGDAGGSGGGARTGGSSAPQPAWVVPVAATLAAVGGVLLFSLAAALVVGRTRHRRRHELAAKASDTEPAGGDARVPSSSYLPSRADSSRDQQSPTHRSTRGGTPQSSGWTLVTNLLFALRSNSNSSSRRSSGRHARKNSSKQRNPSGAASLRFSQLDSNGRADRSTTPGAGTASVVGLVLESQSVALPKTQQLSADAMAAVAAAQGSRLWRSLDVSILLKSPESRAAVGRAVGGAVRGVSGTASSKVVVLSVACRVSPVAAQGASVRAVAEKQQQQQQQQQQQRQRQQGQQEQRQQDANPRPHVSSADPRNANSITADSSSEAATLASPTTGTGTTATGTGTAMSSPAVLTSPATGAATVTAEVAAVFAGDGAAAGGRAHDEELWLECVIGRGGFGVVYLGTWRGLPVAVKTLVVHEALLGEEGRRRQRAVLEAAVSSTLCHVNVVRTYAFDVRRLGELPGVRSGGRGTAPALEVVAEEGNQEEQHRPRQPPAAPGLDGKADSVYQLLLIQEYCEGGSLQEGIETSRLYMGLAPDSLGGVLLGLCLALDVAAGMAHVHARGIVHGDLSSGNILLSARPPVVQAADLHSVSTWGCSLSASAGASMDARGGAAASGAGPLARTELPVAGEVGRIMAPAADCEDAPAAAAETAARALITDVMQPPVMARIADFGLSARMGEGQTHASNCWQGTPAYTAPELELEGRLSKAADVYSFGVVLLELLTGQTVEGLLSMAPIFASGAASSSSPAATAAAAAAAAAAAATDGCGGHVVSGAGGRAPPLAASLLTGRCGAAHAAAALRSTAPKVLHLPHAASKERLMLLVGSCLSPAPHDRPTFTQMLHELGAIIAGLDSSLPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W6L1</accession>
    <name>A0A835W6L1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_006604</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000041">
        <property type="protein sequence ID" value="KAG2439079.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="537063at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001881">
        <property type="entry name" value="EGF-like_Ca-bd_dom"/>
    </dbReference>
    <dbReference type="SMART" id="SM00179">
        <property type="entry name" value="EGF_CA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1 2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="2" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EGF-like" evidence="3">
        <location>
            <begin position="139"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="148"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="2">
        <location>
            <begin position="167"/>
            <end position="176"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2439079.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1639" mass="178971" checksum="F886BB45A98AF77D" modified="2021-09-29" version="1">MIATPDGFVHASVAGSADLICVRDGSDCQEKDPYLFPTLHTSCHDADGCHAGWTWDAALAHCVDVDECAPGSPYNRCGDVAECINIVGNHVCVCPQLQDTYGGTYEGRYRFDRESQRCIDDTASPPCVWPQFRFGGQCVDDPCQFKPCGEHERCISAPDGTDYFCACKGRRVDGVCKLSPCLTSPCPEPWATCYNNDDWRGRRCAGSSCDGVECDDGEHCNSGVCVPDSDKSCNLPESWCDGDGEILAKADCGDGDGIDDWACFAPSTGRRAVLLSSNCSAGTDYWPDAPKALCPPLFNNLTCPLPWDEWCTDPGYVRRKLDCGDGDGIDDWTCTRPALGQRGVLLSSDCDAGDRWPEADVALCPPLFNRTICPLPSDDWCRGEGLLQEQLDCGDGDAVPDWVCHHNVTFQRKVLLSSNCSTDHWPQADTSLCPPRFASMPCPQPDNWCDGAGEVSELSNCGDGDSIGDWTCIAANTSRRAVLLSTTNCTLDYWPEAPKSMCPPRFNALMCPLPWDDWCVGDNLVRSKVNCGDDPSTLDWVCVKTNTSGRGVLLSTNCSESHWPDADKSLCPAAFSDLMCPLPWDDWCVGDNLVRSKVNCGDGDAILDWACVQTNTSWRGVLLSSSDCADSHWPDAEKSLCPTAFNGLMCPLPGEEWCTGPGDVREKVDCGDDSGVLDWVCTHPANGQRGVLLSSSDCSDSHWPYANKTLCPARFSDAPCPVPGGWCEASEGEVLHSLDCGDGDGVGDWACVHTDTSRRAVLLSSGSCNTDDAGWPTAVRSMCPPLLNGMMCPLPYGWCEAGDGAVAVVLQRVNCGDGDGIDDWVCSQPATGQRKVLLSSSNCSVDYWPQADAALCPPVFNRSMCAMPYNWWCSGDGFVLEQLDCGDGDSVDDWVCIHTPTGQRKVLLSSSNCSVDYWPTADRSLCPNRFNSAVCPMPYDWWCSGDGLVLEKTDCGDGDAVDDWVCVRNETGQRKVLLSSSNCSVDYWPQAERSLCPKRFNSSMCPMPYDWWCSGDGYVLERTDCGDGDGVLDWTCIHTPTGQRKVLLSSGNCSVDYWPQADKSLCPARFNQALCPMPYTWWCSGDGFELKATDCGDGDGINDWVCVHNATGQRKVLLSSSNCSVDYWPTADKSLCPPVFNQAVCPMPYGWWCAQAGGDVLEQLDCDLDGVPDWLCTNPDSWMRKVLLSSDPSNCTQDYGPAAPRSLCPSRLSKAMCYWPWGDSCSGESYTRQRADCGDGDGIDDWTCVQHNSSYRGVLLSSSACDDSHWRDADKSLCMPVFKDLPCALPWDGWCVGENLVRAQADCGDGDAILDWMCIETNTSRRGVLLSSNCTVDHWGDPDKSLCPAKFQDMMCPLPYYWCDQPGEVLERVPDYCGDGDAIPDWVCTNPTTGQRKLLLSSSDCSNDHAPQADTSLCPARWNGTVCPQPDWWCTDTGEHLERVDCGDGDGVDDWVCLNPSTGQRRVLLSSRCTLSGATEDFWPQADKSLCPNRFNSEPCPQPNYWCSGEGMHIEQLDCGDGDSVPDWVCLHNATGQRAVLLSSGNCSTDYWPQADKSLCPKRFDSLPCPQPYYWCTDSTLTLESVDCADGDSVPDWTCIQNTTNQRAVLLSSGNCSVDYWDTAPISLCPTRFASEYAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WDE3</accession>
    <name>A0A835WDE3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Apyrase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_008769</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the GDA1/CD39 NTPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000027">
        <property type="protein sequence ID" value="KAG2445303.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WDE3"/>
    <dbReference type="OrthoDB" id="6372431at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017110">
        <property type="term" value="F:nucleoside diphosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009134">
        <property type="term" value="P:nucleoside diphosphate catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd24041">
        <property type="entry name" value="ASKHA_NBD_AtAPY1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.420.40:FF:000052">
        <property type="entry name" value="Ectonucleoside triphosphate diphosphohydrolase 5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.420.150">
        <property type="entry name" value="Exopolyphosphatase. Domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000407">
        <property type="entry name" value="GDA1_CD39_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782">
        <property type="entry name" value="ADENOSINE/GUANOSINE DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11782:SF83">
        <property type="entry name" value="GUANOSINE-DIPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01150">
        <property type="entry name" value="GDA1_CD39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01238">
        <property type="entry name" value="GDA1_CD39_NTPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="3">
        <location>
            <position position="182"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="212"/>
            <end position="216"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR600407-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2445303.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="454" mass="49114" checksum="7B6903D0C4E7A906" modified="2021-09-29" version="1">MKRPDTLSDRIWRYRGVLLVVSIPVILILAVIMLVPRSAPFHTERTHTLKELRHTGAAPKYAIVFDAGSTGSRIHVFKFEQAGGELKLISDTFEQLKPGLSSYADSPEKAAASLQPLIDTALKTVPQNLQSSTPISLKATAGLRLLPGDKADNILKAVEALLRKQPFKLAPGGVAIMDGKDEGAFAWLTLNYLLGRLSGPVGKTVAAIDMGGGSIQEAFALEDAHSKLAPTDYVVKLHGGGKTFNVYVHSYLGYGLMAGRAKLIDAGEKGKPHSCIHEGAAGKYAYAGKEYTFAGGETDFEACAQIGGSALLANLTCGPKPQAECSFNGAWRGDGLSKGRDYFVSSYFWDRAFETGIIEDEGAAMWEVTARDFADKADEVCVQTVDDIGKVFKKVQGEHTKFLCLDLTYCHVMLTQGFKLDEMMKLTLVKQVEYNGQRIEAAWPLGAAINDLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WDG0</accession>
    <name>A0A835WDG0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008841</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000027">
        <property type="protein sequence ID" value="KAG2445376.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WDG0"/>
    <dbReference type="OrthoDB" id="546768at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="34"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="113"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="37"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="52"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="141"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2445376.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="194" mass="19887" checksum="79461922F0E63FAF" modified="2021-09-29" version="1">MRLAVLLPVTSRGCQGAGDVRALFARLQRLRRHLDPPAHPAPPDQTQPPSPAAAATAAAQQPQPGDRAGSSSSSGSSWITAAHVCVCLGVDEDDPWLMASELPPAAAAAVAADAPAGPMPEVEGEVQDGSSPAGADGPNGAAARGSSFLVQAFPGLPVRLVVFTRAELELHQVDVVRGGWVDAERVEGERGSRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WFJ3</accession>
    <name>A0A835WFJ3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Nucleotide-diphospho-sugar transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_008505</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000026">
        <property type="protein sequence ID" value="KAG2446518.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WFJ3"/>
    <dbReference type="OrthoDB" id="523829at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2446518.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="689" mass="76070" checksum="1F939501BF7C5EFC" modified="2021-09-29" version="1">MLARIRGQAGYGHAMALMNELHDCQRLARVMQSAHHEQGPISCGAYISKDASGQDFPTGWQLMARHMGFTAWWKKWFTVARAIALGYNVLAVDSDVVVLDDWYWRAKQPPLSNYQLLSQAECPVCINGGFSYIQNANPAGPVAWMFYEAVHRAVRWTEDWSAVAAISPVSAPDHNRVAMVDDQTMLTDVLYNCIVGRPQFMALWYYVKDDPAALQKLQVANESAYRQVNTPADNFTDAVFNVSSELAGLVRESFWNVGADLAAVRLRSAVLRMPHSGGNWPLPHGSYPFNKQPGPRTLAFRQAFKDLGVPLPPDPEDPATEAAARAVAPEKFTFLSLDAGEGIRLGGWAESTWNIIGRLGYWHSHLHPPPVVGMGHIHAGLWPGEGVQKHVVFQATGHFDWRVAARLSGSPSRAYYAAWPGTEAFATAQHDRTLELRRVIAYAPGLVTSALSKQQFLAAVRGLAQVSVALGAVAAWPAVPCDAEWVLSPVGVNMSRPIRHSIPWLHLNTRYVVMPFGDSLDTLKCEWLGFATADCLMDSRRDGKEGGRALTAMEFEHLARRREIEQAGYVPHSTPYNRINELVSLGAPLRHAPNEHNTLRLGSSGPAVGSTGGGQPLAAVALSELRQLNAELLLMNQQPHEPVPVFWLGQLVGEVTGLQGRAAAVYDTWRQRCRALRYEELGEFERNLF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WFJ8</accession>
    <name>A0A835WFJ8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_008503</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000026">
        <property type="protein sequence ID" value="KAG2446515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WFJ8"/>
    <dbReference type="OrthoDB" id="431068at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="129"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2446515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="305" mass="32866" checksum="02E85653FC7EDC69" modified="2021-09-29" version="1">MGSRDRSRSRDRRRSRSRERSRRWDRSRSRDRDRDRDRDRRRSRSKSRSRSRDRNKSSGALDASISAVQAMAALQQQQQLQRQLLAQQMLLQQQAAAAAAAAALSKPAMAQQSTTAATADRKSREIYGRQIYVGNLAIGVVTADMLKELFNTILANQVADPVSTPPVVNVNLDPSAGRFAFIEFRTRELTDAAIQLDKLELCGRQMNIGRPKGYVDPNAHLVNAAKLGQAQVALATAQFALPGAAVPGALPGAAAALPGALPGLAGAAGLAGLMVTTPTAVVLLENMVTCATIRDDTERKEVSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WI16</accession>
    <name>A0A835WI16_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_007017</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell projection</location>
            <location evidence="1">Cilium</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RPGRIP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000019">
        <property type="protein sequence ID" value="KAG2447989.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035869">
        <property type="term" value="C:ciliary transition zone"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005856">
        <property type="term" value="C:cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1905515">
        <property type="term" value="P:non-motile cilium assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021656">
        <property type="entry name" value="C2-C2_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031139">
        <property type="entry name" value="RPGRIP1_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14240:SF1">
        <property type="entry name" value="PROTEIN FANTOM-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14240">
        <property type="entry name" value="RETINITIS PIGMENTOSA GTPASE REGULATOR-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11618">
        <property type="entry name" value="C2-C2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50004">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-0966">Cell projection</keyword>
    <keyword evidence="5" id="KW-0969">Cilium</keyword>
    <keyword evidence="4 7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="321"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="357"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="10">
        <location>
            <begin position="417"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="domain" description="C2" evidence="9">
        <location>
            <begin position="1111"/>
            <end position="1238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="499"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1311"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1390"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1449"/>
            <end position="1635"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="58"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="181"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="548"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="684"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="867"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="506"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1403"/>
            <end position="1414"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1455"/>
            <end position="1467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1488"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1530"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1574"/>
            <end position="1591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1623"/>
            <end position="1634"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006042"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023069"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2447989.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1934" mass="209634" checksum="28F0ECE274A0CA75" modified="2021-09-29" version="1">MGGNDDRGLDGPDESATSFGSLPPPKPVKYAWAPANDRVNHENFHRMLEEYRACKKRERDLELKIKQLGAQLARTEEAAKRALVQTDATAKGGAAQKLLDAERAIAKLRAENAELASKLAREKKRSSDLKAMADTYKHRLDGFLRDQRNLVQKVGQLERTAAASRRKPEDEFWGEEAGRRFVAQQEELVALKEENTALKELMESDGPLAQCKAYEGQINELQNLVKFYERKITAMAEAGMGGLEALGGPGNQPGPDDWVLEEFWHNDEMYLLDRKTGKMFTVPGDNNFPRPLGIRTNKEVKMGIHNSMERFLATLDSFLASNGARLQEVFAQFDVDNSGQLDRRELARLLQTLMPDLNQTQIEELRMMLDVDGDGLISLPEMLESIKEAFAARTAAKVGKNIEVNDALDRIREVLRENKQEVRASFDELDSDKDGCLSHLEVVRLVRRFLKDMYQKEVRYLLAKLQQWDVQGESKVSFDELYQCLELVRVFRVGPGLGGAMRTGSPMRSPTRSASPSKMPTAGPNIRASGPGRASLVRSTVGGGGMKEAFMRERVGQLEAELRDAQRRNSELEDDAKKVELLQRDAALYKARIEELERDFMKIDVLGNLEAAGGDEQLQKAWEIASTFKKRFMEHKGELDNIRILYARMQAQLDETHKLLHEEHRKRFKLEDEITRLNVELMRVQDLESRLTHEKGERVKLEREYLTLQQKALNAPGEALAEVRALREELFAVKREKATAQQKEAEVRMELQHVRTLLDGMDQTSYKAMQDDSDALKKKVASLSLELQAARDKLAVYMRTELPGGAANTDLLFADDDLLFGSDRKPDSDKTPEELRRELIQLRDVWRLDQGEIKKLHKVLETESAITMEAKAAVEEAHREMERVKRELQADLRKLEREIERRDEKIRKLELQLRGAYSGINRALRSSKRGGLRDSIRSDADDLSELGEDQNIFELHVTEAQIYEEALGKDPAVFFTFDFFMHESQATPIVSSNAPSFNTVIQYVVDSDPFLLDYLDTHVLELELCRARGYDYDVLGVARFSLKQVLEDLEIGAALGYNRAYHYADVFGADGKRLGRLRYGYCFRRPLDALLKEWRVASRHKRRSSEPDERDPATAAVQQALTQPGNSQAVKVIIERCDGLVPAGGTALTMRPYVYYRFPGHRDYRDTQTLAGAHPVFNDEAVWPIARTPALEADLRTRHLQLVVFDDSQSDDPLRAIVGVASVPLAGLAQGVPVEGAFKLTNPVTRQPAGRLVLGLGWHNPLQLPGAVPKPPPPRVPISSEPLEGGPTPDFGLGAGVQELFPVGGGVRPGGFGPGGPGHPLPRPSPAGGQGATFYAQPQPGVQPPQPGGARLYQGQQPYEAHGLAAELGGNNGGRPGGRVSEYGLAADTRQGAPAPMQPPYGPHGGGGAYGGGPGAPGSGFGLAAEAAARQPPAHMGIHGQQQLQQGLYEPSSQYGGGQQPYGGGPGQQRVSDYGLAADTRDQYGAQGPYGPGGVGGGIGGLPGQGQGLYGGPAPGQSPLRPGGRPPLQPQQQQQEFGLGAEAAAAGYGMGAHPPPAGGMQRQGSFGRPPPGPLGGGVGSRLGGPAGGGGLRPPSDAAYGMQAETGAGYPPRPGQPPLRQGSFGAGGGGGGEEFGLGAEVDVAASPPPPGNMMLPPSRGPGGGGAGGRTRYGADTELSLEQQQLPVGPDTATLQHAYHPAQQMSALLPPAAPAPPANAGLGPVLRRERPELSAWMGREYRILFCLHSIELTQQTLRNPNVSAVVVCHSLLEEGEAAGNGISMLDTYSKPLAKAPGQLPINYCVAYNILAGNAASELYAGLTGPGGADFSLELSLMYTSGGVAEAAAALAPAGGSGSEVAPGMFRVLGGAALPLAELWTRRRGDLIMERVEVLEDADDPGSVVAVLSVSLVAEAALATLRETMRHRGGAGGGVPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WI26</accession>
    <name>A0A835WI26_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">starch synthase</fullName>
            <ecNumber evidence="4">2.4.1.21</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_007224</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[(1-&gt;4)-alpha-D-glucosyl](n) + ADP-alpha-D-glucose = [(1-&gt;4)-alpha-D-glucosyl](n+1) + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18189"/>
            <dbReference type="Rhea" id="RHEA-COMP:9584"/>
            <dbReference type="Rhea" id="RHEA-COMP:9587"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:15444"/>
            <dbReference type="ChEBI" id="CHEBI:57498"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.4.1.21"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Glycan biosynthesis; starch biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the glycosyltransferase 1 family. Bacterial/plant glycogen synthase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.4.1.21" evidence="4"/>
    <dbReference type="EMBL" id="JAEHOD010000020">
        <property type="protein sequence ID" value="KAG2447767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WI26"/>
    <dbReference type="OrthoDB" id="2018403at2759"/>
    <dbReference type="UniPathway" id="UPA00152"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009011">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (ADP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004373">
        <property type="term" value="F:alpha-1,4-glucan glucosyltransferase (UDP-glucose donor) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019252">
        <property type="term" value="P:starch biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd03791">
        <property type="entry name" value="GT5_Glycogen_synthase_DULL1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00484">
        <property type="entry name" value="Glycogen_synth"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005085">
        <property type="entry name" value="CBM25"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001296">
        <property type="entry name" value="Glyco_trans_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011835">
        <property type="entry name" value="GS/SS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013534">
        <property type="entry name" value="Starch_synth_cat_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46083">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46083:SF5">
        <property type="entry name" value="STARCH SYNTHASE 3, CHLOROPLASTIC_AMYLOPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16760">
        <property type="entry name" value="CBM53"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08323">
        <property type="entry name" value="Glyco_transf_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00534">
        <property type="entry name" value="Glycos_transf_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01066">
        <property type="entry name" value="CBM_25"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0750">Starch biosynthesis</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Carbohydrate binding module family 25" evidence="10">
        <location>
            <begin position="303"/>
            <end position="396"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate binding module family 25" evidence="10">
        <location>
            <begin position="487"/>
            <end position="589"/>
        </location>
    </feature>
    <feature type="domain" description="Carbohydrate binding module family 25" evidence="10">
        <location>
            <begin position="662"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="122"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="167"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="216"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="412"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="123"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004727"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00010281"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012588"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022922"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM01066"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2447767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1221" mass="134841" checksum="980C7663ECDA0578" modified="2021-09-29" version="1">MASSMGRALQPQLGAQRSVRQGASRIRGAQGPRTVPSFGLKALRKEDAELLKEAESYMSPEEHTELRRLLEENQRLRQVVTTSASQMSPQQLERFTAEYKNLAAAAEQAGLAVDQQLKQQITAPQAAASPSRSSSASGTGRFEAAAGASGGYGYGRSSVSVLVAEPPAAPPASAAPPPPPPSFGSGGGSPKGGATAFEVSSRDYAKDMASLSVELDATIDDEEDHDVPPRKAQMLDAREKKQKSAAAGDYGALNGASAADDKAAKEAARAAAIAEVEGHRAADVVAGREHWMIITVPEKPVAGAPLQMYFNRNQSEKLRNRPHIVMQYGFNHWELQPEAGNSVDLFPAPTPKSDVTDFWTCRVQVPEDTYELNFILHDKAGAYENNNGMDFTYPAEAGIDYDTWVDTAAERIVAKELARREAEAKAAEEERKAAAALMEQQAKEFGEKKAAELKNNLSGLQEGGTAALLRNGVPVYKVTPSFPVAGGKAVVAYNRKGGSFNNFPIPEGEAVNLLYGFNGWQQSGKAAMRRVPAAPKPTGAVAGTKPVEDEEWWEVEVQIPNIAVAMNFVFNYYEHYDNNAKADYKVKVGLPAGKTLEAWAAGLSEEYRVMELAKRRAEMAEREEKQRRSDEKKKLAQDLVKAVERRKVRHVLYTVPEVVEAGEEVTIFYNPRDTPLNGRQQLYLMGGWNRWTHKRSFGPVAMHPPEDGGEHWQATVVVPKDAYKMDFVFADVPGGDGTYDNRGGFDYHLPVEGSPVRESPLYVAHIAVEMAPIAKVGGLGDVVTALGRAVKEQGHMVEVILPRYDFFLHSPVLQGQLKYETEFDWGGTRIYVTTAVVENLRVFFIEPKNGFFATPTVYGRYDDEVRFDFFCKAALEFLLKTGRQPDILHCHDWSTAHVAQSYWNDYHSYGLHKPRVIFTIHNLNYGQKKIGEAAHACQKFTTVSPTYAYEVGGAPIIAPHGHKFMGIRNGIDPELWSPEDNIFLPVKYTSETVVEGKKAAREALRQRLNLTGWNDKFIVAVVSRLTGQKGVPLIKHAAYRTVERGGQFVLLGSAPDPKVQADFDALASSMGGQDAAFQFKYDEPLSHLIYAAADMIVVPSMFEPCGLTQMIAMRYGTVPIVRHTGGLRDTVFDVDFDKERAAWELYGSSDWQRDGIDATNGFAFTGTDGGALDYAMNRAIDAWYNDREWFRGLQRRIMEQDWSWNRPAIDYIELYFSALKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJ06</accession>
    <name>A0A835WJ06_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_006914</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000018">
        <property type="protein sequence ID" value="KAG2448330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJ06"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1080">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011709">
        <property type="entry name" value="DEAD-box_helicase_OB_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF109">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21010">
        <property type="entry name" value="HA2_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07717">
        <property type="entry name" value="OB_NTP_bind"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0347">Helicase</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DEAD-box helicase OB fold" evidence="7">
        <location>
            <begin position="112"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF07717"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2448330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="218" mass="25409" checksum="6BF134C44ADD71E2" modified="2021-09-29" version="1">MAPPRCSNEILSIAAMLSSPNVFLRPREAAKAADEAKARFTHIDGDHLTMLNVFHAWKSHNEDSNWCYEHFLNFRSLKSADSVRTQLSRICTRMNLKLVSTPFESKEYYSNIRKAVTSGFFMQVAHLQRQGQYMTVKDNQVVHLHPSTCLDHKPEWVLYQEFVLTTKNYIRTCLDINGEWLIDVAPHYFDLSNFPPGECKRALERMYAKKEKDKSDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJ15</accession>
    <name>A0A835WJ15_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_006699</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000018">
        <property type="protein sequence ID" value="KAG2448114.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJ15"/>
    <dbReference type="OrthoDB" id="551458at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032595665" evidence="3">
        <location>
            <begin position="24"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="163"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="295"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="191"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="203"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="295"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2448114.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="341" mass="35576" checksum="832F8890723FA477" modified="2021-09-29" version="1">MGLVGADMLFFLVCLLVQAFTSGLHMGRKWSSVGVNGVNLYWWPTPKTLTLEEVAFSLVVDLVGVMAGFQEKPPVLGLFLLLDLITTILIGIHGISLFLLFRGVQMAVCILYRNALVHCMGMCMTEVERLEFLSTELGIMTILHTMAGFCGVLCGIEPQQAQRASRDGQEAAASPSLREGSAAPPPEQIMATPSTMSRTASIAGTAAEPGTEPEGGTAETDGAQPQPSSSPTLMLLAPTAGQALERQHQPSVLGADVPIPARGALAPAGTVSGAEPLTTVAVFSFAAGAAHASVQRSDTASSRQPDVSANATAAGPADWCLTSGRSNCGGGRRLEWQQWGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJ23</accession>
    <name>A0A835WJ23_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_006373</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000017">
        <property type="protein sequence ID" value="KAG2448482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10678941at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="146"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="78"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="680"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="738"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="834"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="911"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1145"/>
            <end position="1203"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1282"/>
            <end position="1313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1421"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1475"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1603"/>
            <end position="1680"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="119"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="129"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="751"/>
            <end position="767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="834"/>
            <end position="844"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1151"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1184"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1475"/>
            <end position="1502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1522"/>
            <end position="1544"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1603"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1652"/>
            <end position="1661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1669"/>
            <end position="1680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2448482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1680" mass="161672" checksum="B78E312B9093EB3E" modified="2021-09-29" version="1">MDISSVGLCSVATAPPHVRTRVVLALAPIASNSTNSTSPGGGSACVPLTAAALSRFQEEAEAVAAPLNLNPAPPSILNLNLGLDFPPPPPPGGKTQQQQDPAPGEPLHSAVGDGDASTAIGNATLVSTGGSSSSSSSSKKGGGIPAWVWVVVAAGAVLMLTGCFVLGGFVRRQHGRRQYRQDRAATSAEVVAAAAGGNMVVALPATDPGDREMALAAAAAAAAATGPAASGAEPRRSRLQLSAAARGGAGVSASGASFSGVVMAAAGTGSGGASPSAALAAAGGQDRSVNPRRSSIASVGDIEASVHGGSGASLRGGASRRVSIAAAGDEDSPRSLLLAKSVKRVASIHGGGRSHVDLAGGIYVGAFGGGDDSGDVAAAATAGPAAGSGSLPLPLGLHAGGDYELEEQRLTTAGAASRGPSRMPSFSEAGAGAPGPNLHLDPATAGAAAALGARSRRASSVRRGSSFYQLAAAPVVSASGVAAAAPLPLSSARSRRASMPTMMGDDLLVMAAAGRGAGARGGDALIAAAAAAAAGAGSVGGGRGGGDMDAQRPSGGGAAARRRFSAVTFASGTQPFLPRRAVGSVTGEAYGLGNAHDDRAGDAGAPPAVFATASGIPLQPPAKPSGGPLIISSSRAAFLSLGALRSDGHSRLSRGDLATAAAAAGGGVSVGGMVAAGDASAHGGAGAGVGSRAGSRSIRRPAWAGPGDARESHAGGDGGTVLSASQVMIDTQTMALGHGSGLAGAEPGGPSPFATTSLTPSATTTQTSHSLTGVAVAPGAAAAAAGRATLDSTSANRPRWASLMGTAATGPLSSNFSRSRFSVAQVPLEGAAPASAAASAPDAAGSRHRSRSTDAAGWPTLGGATPHARLREVLAGAGIAPGANAPAHEAGAALPAAAAAGAFAVSGGVAESPEASGSIDVPRDSNDGGGGNAAGGNKRSSLAGALGRSITMGLSRSRRASFTALSHMISGSFRRAPATAAIVPDNTIRVRPAGGDGAAGSGAIGQPATDLGGLRSQPIYVALPSGGLPSDPDAGGAASAPLLRLAAAGGSAATPRVMAAASPLASVLSGSPSRAVSGAGSAVSSTSVPQLQVLRSPSFGGGSAVAPVNPGGASTGAAAFGSPAASIGAIPSPREAAGLDGAGAERELQPPLAPPPLAPEPDQPPPYMVMPAARRAGPAPPSAAPSLTLGPALPAGASGTLDEDDGLEREFMMESLLPPPPSSSGNAGPLSTLMTTTNNNVEELAAAMASAGGSGAGSGAASTAAGAAAWGVRRLVPLSGKSGRGGAGAAGLGAGGGSDASGGGSARAGGAGAAGAADGNLVRGFSSLLDSNPGRAVPAGGRPVGMPALRDNPLAHQQASSSLLMSDLDGSATAAVAAGAAVSASNAAVSSANAEAPGALAPMVLQSASSSLFSLGGGLSSTAGGGAAPGAAVERSPRVPPPAATPDTDRGTPLLVSYQKLEELTNDLLLVPRLHSQSAQQQHQHQQQKQQAPPSPQQPRQAGAVPQLQSRQSIKVPRLNVAPSSQSVGDTSGPPTSASFTGLSSVLYGDAAAAPPPTSARPVSPIGTLGFASPPARKPPPAVPVPDASSSPAVIAVEAQLDAADAPVTASASAKPVAAAAKPDAAAAAATEDDWEPPGWSPSEELERQRQRLAAQRQRLGQQKERLAQRQQHVQQQQQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJ29</accession>
    <name>A0A835WJ29_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Mechanosensitive ion channel MscS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_006494</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the MscS (TC 1.A.23) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000017">
        <property type="protein sequence ID" value="KAG2448604.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJ29"/>
    <dbReference type="OrthoDB" id="431980at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0055085">
        <property type="term" value="P:transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1260">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.30.60">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010920">
        <property type="entry name" value="LSM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023408">
        <property type="entry name" value="MscS_beta-dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006685">
        <property type="entry name" value="MscS_channel_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011014">
        <property type="entry name" value="MscS_channel_TM-2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566:SF5">
        <property type="entry name" value="MECHANOSENSITIVE ION CHANNEL PROTEIN 1, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30566">
        <property type="entry name" value="YNAI-RELATED MECHANOSENSITIVE ION CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00924">
        <property type="entry name" value="MS_channel_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82861">
        <property type="entry name" value="Mechanosensitive channel protein MscS (YggB), transmembrane region"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50182">
        <property type="entry name" value="Sm-like ribonucleoproteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="12"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="68"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="domain" description="Mechanosensitive ion channel MscS" evidence="7">
        <location>
            <begin position="294"/>
            <end position="364"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008017"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF00924"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2448604.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="536" mass="55220" checksum="4BBF6B7216C1DDED" modified="2021-09-29" version="1">MWPWLPHAAESSAVTVVAAAAAAPVLTVAVAAAAMSVPPPHPPPPPYVPPDPALVATLHPGTAALRQAGLEVAAHVLLPLLALWALQRWLAGLEARTKQEVQEGVAAARRSGAAGGAPSLARELADALPIAATAPSRVVLAALTATHVARSLANTAQGLAERALLDGWLGGPDSQAWVLGCRVADLVEGASGSLARLDQVLVVVYQMLLVAFVTWVLLSWKDVALSRFLLRAHDTAAGRQDLERILTPLNTVATWALVVCAGVVVVSLVGVDVRPLLVLTGGGGVVAGLASQQLLSNAVSGLQMYMDRPFRVGDTIAVTAGVNTYLGEVVEVAALRTHLALEDGSTVALPNRSLSDMVITNKSRTSRGLNRPPWLDSRTPLSLQLRVRLRPATYADLGAELAGLQTAILASDAVEAEGAVAPRLEVAGYSDRGVEVLARVRLRNPSKLAAAAASGSLAPPPFLPMPQQATVAATSLGLHEAGPVVSGGGSGAGSSGGGSRAGRSRCSVEAVRALRQQLLLALGPWLQDHNATLAIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJ47</accession>
    <name>A0A835WJ47_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RanBP2-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_006521</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000017">
        <property type="protein sequence ID" value="KAG2448634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJ47"/>
    <dbReference type="OrthoDB" id="549419at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1060.10">
        <property type="entry name" value="Zinc finger, RanBP2-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001876">
        <property type="entry name" value="Znf_RanBP2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036443">
        <property type="entry name" value="Znf_RanBP2_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00547">
        <property type="entry name" value="ZnF_RBZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF90209">
        <property type="entry name" value="Ran binding protein zinc finger-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01358">
        <property type="entry name" value="ZF_RANBP2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50199">
        <property type="entry name" value="ZF_RANBP2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RanBP2-type" evidence="6">
        <location>
            <begin position="302"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="52"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="393"/>
            <end position="718"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="69"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="434"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="469"/>
            <end position="480"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="481"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="516"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="588"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="618"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="648"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="675"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="694"/>
            <end position="703"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00322"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50199"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2448634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="718" mass="75580" checksum="D21DCE16F142D3B1" modified="2021-09-29" version="1">MLGHSSLGQLRHGANYSLRLAPPVSFVAGRALLATSGHRQLCFASAAASSAHAPSSGDSEPAAHPPPLTASETPAATASASLRAETGASNLELWHALLRVLHEQGDFEDPDTPVDELLDEHDDVKAALLSFARRRPDILFSLPEDKLSGLAAVEPLPRDKPDRKLRNAARRLAETYARSRIRLGAGALREHASFQDAMRVLWDWAEAAPGRVEAAAPGLGGLVKELLVRVTAAASSEPAAEAMARAAELEAEMGTPSAAALAERAATELTPEQRRRAKEAEAAARKHQQRLRRAAANGNVVEAGDWFCGECGAANYSDRRRCFRCDYSSEARSNTVVSQDDIRELYGSRPPRRRKPRGVVEAAATADADSMYGAQAAAAAAAAADVAAGAAQAAAPSRSAKPGRDAAPGRRGPTQLEEDADHDDAAVRRGAQKPWERRQQDGDRPPRPQGRPGLRWRADAEDEAGGGEVEGRRGRSRRVDAEEEAAADGEEAGPGTTEARHTPAYRRNMRDFYGSNGAGSSGSGSGRQQGFRGRDRDADVDGGELGGSRAGSSRRKGWLHEVEEDGGGEGGGTSAGARRVRGGALGRDAWEPRTRGGRAEEATGDGGGDLSWEEWESPKPASKPAAAAAPAPSRGPRSQGQEEAAPAEAREQRSAGRGWKEEEGEEDVRRVGRPSRGGRGGGGGRGRGGRGESSRGSAGAGRRSWVEPPPIGGRRAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJR4</accession>
    <name>A0A835WJR4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Coenzyme Q-binding protein COQ10 START domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005704</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2448948.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJR4"/>
    <dbReference type="OrthoDB" id="530906at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.530.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023393">
        <property type="entry name" value="START-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31385">
        <property type="entry name" value="PUTATIVE (DUF220)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31385:SF1">
        <property type="entry name" value="PUTATIVE (DUF220)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55961">
        <property type="entry name" value="Bet v1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2448948.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="284" mass="31645" checksum="318686F0DC8F0562" modified="2021-09-29" version="1">MGKEDSQKEDRGTTEAWNEKNQAITVTEGNGFLYNLKLRAKVDASPSEIYDILTDPNTVSIFRSIKECTYRKEVENDGKGRRKLEIGHKALARFLFISITFETHLYVWEDDVAKTIRFQMAKPGMMQKFDGCWEVKPFTQATLDAIYNPEKAAAKAAAHHHHNPFGPQGLFSFLGPKPVEATESLVTLEQSILPRGPTPPGVKGLIRGLCAHQIRCMMEDLRKELQRRKDGTSWIKPVAHGEEGEEARKGGSIGKLRQQAAPAASLGLASLWHSAAPINIVVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJU7</accession>
    <name>A0A835WJU7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">phosphatidylinositol 3-kinase</fullName>
            <ecNumber evidence="1">2.7.1.137</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_006498</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="6">Belongs to the PI3/PI4-kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.1.137" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000017">
        <property type="protein sequence ID" value="KAG2448608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJU7"/>
    <dbReference type="OrthoDB" id="67688at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005768">
        <property type="term" value="C:endosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000407">
        <property type="term" value="C:phagophore assembly site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034271">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type I"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034272">
        <property type="term" value="C:phosphatidylinositol 3-kinase complex, class III, type II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016303">
        <property type="term" value="F:1-phosphatidylinositol-3-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000045">
        <property type="term" value="P:autophagosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048015">
        <property type="term" value="P:phosphatidylinositol-mediated signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00870">
        <property type="entry name" value="PI3Ka_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00896">
        <property type="entry name" value="PI3Kc_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1070.11:FF:000002">
        <property type="entry name" value="Phosphatidylinositol 3-kinase catalytic subunit type 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1070.11">
        <property type="entry name" value="Phosphatidylinositol 3-/4-kinase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1010.10">
        <property type="entry name" value="Phosphatidylinositol 3-kinase Catalytic Subunit, Chain A, domain 4"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.70">
        <property type="entry name" value="Phosphatidylinositol 3-kinase, accessory domain (PIK)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057756">
        <property type="entry name" value="PI3-kinase_type3/VPS34_cat"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015433">
        <property type="entry name" value="PI3/4_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000403">
        <property type="entry name" value="PI3/4_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036940">
        <property type="entry name" value="PI3/4_kinase_cat_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018936">
        <property type="entry name" value="PI3/4_kinase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002420">
        <property type="entry name" value="PI3K-type_C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001263">
        <property type="entry name" value="PI3K_accessory_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042236">
        <property type="entry name" value="PI3K_accessory_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048:SF7">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL 3-KINASE CATALYTIC SUBUNIT TYPE 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10048">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00454">
        <property type="entry name" value="PI3_PI4_kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00792">
        <property type="entry name" value="PI3K_C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00613">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00145">
        <property type="entry name" value="PI3Ka"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00146">
        <property type="entry name" value="PI3Kc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51547">
        <property type="entry name" value="C2_PI3K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00916">
        <property type="entry name" value="PI3_4_KINASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50290">
        <property type="entry name" value="PI3_4_KINASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51545">
        <property type="entry name" value="PIK_HELICAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="C2 PI3K-type" evidence="10">
        <location>
            <begin position="113"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="domain" description="PIK helical" evidence="9">
        <location>
            <begin position="477"/>
            <end position="653"/>
        </location>
    </feature>
    <feature type="domain" description="PI3K/PI4K catalytic" evidence="8">
        <location>
            <begin position="894"/>
            <end position="1177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="164"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="762"/>
            <end position="910"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="176"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="811"/>
            <end position="829"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="833"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="871"/>
            <end position="889"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012073"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00880"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50290"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51545"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2448608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1192" mass="124234" checksum="350BD38BE556091B" modified="2021-09-29" version="1">MWGTVPAGRGGGGATGGTAAGARGGLASGQFSFYVSCDINLNVRVKVSELQGLLPSARSSLPAALTNVTGVGAGGVGGVVGGGLGGTGVPVGHDATWPSHPSSAAATAAAAAAAATAGSTNGSGTGVTSAGPKTSSLYVIARLTSCGETLGLEATTAYAEAVCSPAPQRPQPPMLSASSSAAAATASESSAEEAAQAQAQEAQEAAVAGEAAGGGGGAGDVSTARWDEWLTFCVKYRDLPPDTQLVLVLVEAAEGRGREALVGSTVMPLFSKRGRLKTGPQRLAVWEGTPPCTQFPTSTPGKAPLAHRDRLARLEHLLHRHQRGEMAPGPGGEWLDGLTLAEIRRLAAADRAAWRSRPELRLTVLLPLFPHPVLCYQHVSAAAGAAAAAAAAGAAGREGVGGAAAGGAGAGWGQAGKREAGAGLLTSPDASVSAGAGAGGGVGGALIRLVDPEVGRDNPAELKAQKLARGLQRGVLDRDLKPNSEERRKLQAILKLPPNKPLHAEERALLWRFRASLTQDTRALTKFLQCVDWSDATEAKQAAELMRQWAPISAADALELLSPDFRAEGVRQHAVQALQAVDADELGAYLLQLVQALRYEAADTGSRLGAFLVQRAADDPALAVQLHWYLFCELDDPGFGLRARALHTQLLETLASGGPGSQGLVIADTIRRQVDLVKQLKAVIRELKSSKIKAARATERLREMVSENGPCGELTALRVPLPLDPHIVLAGIVPKECSVFKSAMLPLRLSFRIEAAPMNWKAPLLPPPPPGPHDPHSHPHQQHHYHSSSSQPGQRHPHQHQHPGGGGGGSHLSSGSVGSGSSSGAVHSPLGHTAGGGGGGGSYWQPPSDPLALLPTRTGIIPAPPGAPDAAGGGGGAAASGSHHGGSAGGHSHHGEGGGLAAAAAGPPPPGAPPPVLAGYRCCIIYKKGDDLRQDHFVLQMIGLMDRMLKRENLDLRMTPYKVLPTSCDDGLLEFVPSVPLSAVLAEHKTIHRFLALTQADPGGPFGLRAEVVETFVRSCAGYCVMTYILGVGDRHLDNLMLTHDGRLFHIDFGYILGADPKPFPPPMKLCKEMIEAMGGQGSDYYKQFRMYACEAYNILRKRADLLLSLFHLMAGASIEAIRADPEKAILKLQARGWGLGAGRSRAPMDKFRLDFDDEAAVEWMQGLINESATALLPQLVETTHRWAQYWR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WK16</accession>
    <name>A0A835WK16_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Triosephosphate isomerase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_005774</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="4">Carbohydrate biosynthesis.</text>
    </comment>
    <comment type="subunit">
        <text evidence="2">Homodimer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the triosephosphate isomerase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2449022.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WK16"/>
    <dbReference type="OrthoDB" id="547231at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004807">
        <property type="term" value="F:triose-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046166">
        <property type="term" value="P:glyceraldehyde-3-phosphate biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019563">
        <property type="term" value="P:glycerol catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035990">
        <property type="entry name" value="TIM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000652">
        <property type="entry name" value="Triosephosphate_isomerase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21139:SF2">
        <property type="entry name" value="TRIOSEPHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00121">
        <property type="entry name" value="TIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51351">
        <property type="entry name" value="Triosephosphate isomerase (TIM)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51440">
        <property type="entry name" value="TIM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0413">Isomerase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="447"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="512"/>
            <end position="577"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="512"/>
            <end position="526"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00024331"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2449022.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="644" mass="68172" checksum="65D0965D0D750575" modified="2021-09-29" version="1">MQLCKLSQRPAVRGSRSRSARVEVVCSSSAKFFVGGNWKANGSTASVAKLVDELNAGTIPRGIDVVVSPPFIYIDYVMQHLDRAKYQLAAQNAWIGGNGAFTLPVLPRLKGAITALSWVNGVAHKLVCASAGGHIFIADVIKPEDSSQKPYEFPQAIHEIHTLPNEPFALCICRGHTSSDGEIASTHRGGRGGPSILSTMAGHGHGGAGHDVMRVPAQRPRVFWYNVLEEKPVAELMGPRAGQGFGLACCVPPPPSLAPPPRPTTADTVVEGGAADGKSAAASAAATPQPGAAPKGKGGAANAAAAAAAAPPAGAPAAASQEASPEPAMNEAQRALIKAALDAMGANSSTPVLVPVKLHVPPGQVVPYPACVFRDTYLLAGGDVVDKVVRSNFADDDAVPQRVTQLYMYKVDALLRHLLPEDESTSRLGKVVLDRLLADLEAPKMNKKKGKRVKMDVEDPDAPKLNSAMRKPDPFDTTGSRPGSRAANRHITFGGGDTDGLFDDVLEGGRAKPKKETKVFPKETKKGLKTGPGDVKMLDKNASGRPRLAPLDLDKAKEAPPPFSERSQSPPWHHTNPLARIHPDWEEAPVLVRIMDRIGSKGGGRKRRDKRLETLTTELMTKYAKEAGAKPNLFVDLPAAGQLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WK32</accession>
    <name>A0A835WK32_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_006084</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000016">
        <property type="protein sequence ID" value="KAG2448728.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WK32"/>
    <dbReference type="OrthoDB" id="550884at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="23"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="262"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="331"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="450"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="676"/>
            <end position="699"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="762"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="809"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="963"/>
            <end position="1093"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="74"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="457"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="763"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="809"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="837"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="963"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1020"/>
            <end position="1033"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1045"/>
            <end position="1063"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1064"/>
            <end position="1074"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2448728.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1106" mass="108663" checksum="4A693469DA9EDA8D" modified="2021-09-29" version="1">MDTGPEALDPGASRAWGFVFAASPTTPEQPEVAPATPHTIDSNVMVVATPKGHDTGGDDGPSFSLGATPLSSARAVPGSVGSSRSGGPAHRRSGLAGGSPATHYRGGNTTTTRIKPQAHSAASPAAVVAPMATGASPPVGWPPLTAPAGDAATAPASLLGSFAQAAAGSATAAGPVWGSAPTDRQQPAGAVASFAAQPAFPPAQLQPREAQLLPPGGQEQQQQQQPQSDDGHCYLDDLVQLLLQPDDDDGGGQEQAWLQQAGAAGGAGYHSGRGTEGAIPGGGGGGGGGDVSPDNNGAKEPLNDLHALAAALEAAEAALGAQDFDLGPLLPAADFDEDADAGDGDSGGVWGSSPSGPGDEEEHPANRQQRRARLVAKRTAAAAAAVAAPGTGPTAGPAAAAATTSEGWHVMLAAPSPHNPENVATLLAAGLLVRPQTAKPAPLLALAMEEEQKRKQQQQQPGGSAANTTTATAAAAAPAGPAAAVLRCSDAVDVEAALGLHGRRVYCPPAVPGGTFAWRPLTVAVQRTPAGAAVPLADRRPPGPSGPRTREAGPTVRRVVMRGVPDHMGADDLAELFGSGLQLPGHCDTPLDRRFLLLCPDHVSFQALLGWHGCRLPVKCVDALQQIVPHRVEGWTQLSVEEDDGVLLPALVSQLLAAARQQAAAGDATAVTTLAAATRPPNHSQQQRFRPPGRFHPADLDLMDEADAEDRALEEAEEAAALLAAEAAARQTAAAAAAAAAVAAPKARVGAQVPGVPDTQGKLLAAAGSSGSSRSSSLSAPEGVGGAAGSAAAAAAAFSSSQAGGGRAAALASVSRPRGKGASQSGSHGAGGESDEVAAAAAAAAERAESSRGASSSGLSARPAPRPRRAGAASHFASSAAGGFWGAAPGPGSAASASALNPCACCPLPGTSQLPAPPGGAAAAPNSWSGAAAVELLNKLLALGIDAGLDDDLGAALGGGGGSSDGGVAGGGTRAHRSGGSGAAAVAGGGAEDGPDEAPYFRRSRKRMSTHFDRRPEDYSDHEEEEEEEEGLEADSQGGEEAGQQEEGLAQQDATAAAVVGTTGDEGVGLGGAAGPAPAALGSGGGGNSSHALSALNAADDLHALL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WL79</accession>
    <name>A0A835WL79_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="23">Endoplasmic reticulum oxidoreductin 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="21" type="ORF">HYH02_005299</name>
    </gene>
    <organism evidence="21 22">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="21" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="21">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 17">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="4">May function both as a monomer and a homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Endoplasmic reticulum membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
            <orientation evidence="2">Lumenal side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the EROs family.</text>
    </comment>
    <comment type="caution">
        <text evidence="21">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449774.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WL79"/>
    <dbReference type="OrthoDB" id="269384at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071949">
        <property type="term" value="F:FAD binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015035">
        <property type="term" value="F:protein-disulfide reductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016972">
        <property type="term" value="F:thiol oxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034975">
        <property type="term" value="P:protein folding in endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007266">
        <property type="entry name" value="Ero1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037192">
        <property type="entry name" value="ERO1-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613:SF0">
        <property type="entry name" value="ERO1-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12613">
        <property type="entry name" value="ERO1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04137">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF017205">
        <property type="entry name" value="ERO1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110019">
        <property type="entry name" value="ERO1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="13 18" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0249">Electron transport</keyword>
    <keyword evidence="8" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="9 17" id="KW-0274">FAD</keyword>
    <keyword evidence="6" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="14" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="15" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="22" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7 20" id="KW-0732">Signal</keyword>
    <keyword evidence="5" id="KW-0813">Transport</keyword>
    <feature type="signal peptide" evidence="20">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032528224" description="Endoplasmic reticulum oxidoreductin 1" evidence="20">
        <location>
            <begin position="29"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="19">
        <location>
            <begin position="259"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="19">
        <location>
            <begin position="259"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="active site" description="Nucleophile" evidence="16">
        <location>
            <position position="432"/>
        </location>
    </feature>
    <feature type="active site" evidence="16">
        <location>
            <position position="435"/>
        </location>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="231"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="233"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="244"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="296"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="299"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="17">
        <location>
            <position position="329"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="137"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="18">
        <location>
            <begin position="432"/>
            <end position="435"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004367"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00011802"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="18">
        <source>
            <dbReference type="PIRSR" id="PIRSR017205-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="19">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="20">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="21">
        <source>
            <dbReference type="EMBL" id="KAG2449774.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="22">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="23">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="523" mass="57055" checksum="FBA12398EF1CABE7" modified="2021-09-29" version="1">MRRLRPLCSLAAGVCLLALLQLQHTVVAGGAQTNLTGISAAALGAEPAADAFSTNRQLVGQGQEGAATIAADELTAGESCKLSGHVDECCNCTYQDVDRLNAALHPLLRQVVRTPFFRYFKVNIYCDCPLWPDDSMCALRACSVCECEQSEVPPTWRQLEQGGQAAEEEGSCNSNTCAAELDGKVNSTVDPDTALKLLNLKGWRGFNNPWMAEGEGDEEYLYVNLLINPERYTGYAGEHAHRIWRAIYSQSCFRSGSSDSEVSDSSSRSGGPPALSPTSLPPDWCPEKRVFYRLISGMHASISAHISANYLLNEERGQWGHNLTDFRMRLGRPELRDRIENLYFAYLFVLRAVTKAAPLLARYDYVTGFGAEEDAATAQLMKGLLTSPELASSCPMPFDEGRLWKGSDGLALREELRAAFVNITRIMDCVGCEKCKLWGKLQTLGVATALKVLFSSSDCNNALPTSPALSTLALERNEVIALVNLLERFSASIEYYRQLSAELQGVEGVEGAPLPVAIGEPVT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WL82</accession>
    <name>A0A835WL82_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_005659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449515.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WL82"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="366"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2449515.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="366" mass="38624" checksum="350DDF7B9CA4E209" modified="2021-09-29" version="1">MASPKEVEGFAEVVRQAIVETFVRLDNDWIAVGHMSGTTVTATIVIGYLLTVANIGDSSAVLDTGCSILELTGSHRIQSNPEEQTRLRGAGCTLAPLGFHLQGPARQGELGVGPLRLWPGGLCVSRSVGDLDAGPEVVPLPHIRQVLLPSNGARIIVCSDGVWDLMSLSKAVKLCRFKPASAATAALMGAVSRDLRLLDDASIIVVDMLPSDATSWPTVALKANPKPEKSGGLFACFRPELDEPDSRDVHSSAPGHLAFLADLDSLRVYPQMRAALQRTQIQHLATVLNNAVGGKPGIDYTMHGANKVSLYRGYVENGMPRTNSSSTAVADVASEGANHSNHSAHSAGGTAVSEASSPRRAMLREA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WLW8</accession>
    <name>A0A835WLW8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">3-ketoacyl-CoA synthase</fullName>
            <ecNumber evidence="1">2.3.1.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_005315</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Lipid metabolism; fatty acid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the thiolase-like superfamily. Chalcone/stilbene synthases family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.1.-" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449792.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WLW8"/>
    <dbReference type="OrthoDB" id="329835at2759"/>
    <dbReference type="UniPathway" id="UPA00094"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016747">
        <property type="term" value="F:acyltransferase activity, transferring groups other than amino-acyl groups"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006633">
        <property type="term" value="P:fatty acid biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00831">
        <property type="entry name" value="CHS_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.47.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012392">
        <property type="entry name" value="3-ktacl-CoA_syn"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012328">
        <property type="entry name" value="Chalcone/stilbene_synt_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013601">
        <property type="entry name" value="FAE1_typ3_polyketide_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016039">
        <property type="entry name" value="Thiolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31561">
        <property type="entry name" value="3-KETOACYL-COA SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02797">
        <property type="entry name" value="Chal_sti_synt_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08392">
        <property type="entry name" value="FAE1_CUT1_RppA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036417">
        <property type="entry name" value="3-ktacl-CoA_syn"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53901">
        <property type="entry name" value="Thiolase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="47"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="88"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="domain" description="FAE" evidence="4">
        <location>
            <begin position="110"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="domain" description="Chalcone/stilbene synthase C-terminal" evidence="3">
        <location>
            <begin position="418"/>
            <end position="474"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PIRNR" id="PIRNR036417"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02797"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2449792.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="531" mass="59867" checksum="29F3F4B17DED9129" modified="2021-09-29" version="1">MAAPGEPAPAVTATVMTTNGGHRSALNFPDYRRSVALKYVKRGYTFLMSYVLTIALVPLAGMLLLELVNMHRTGELTRLLSVAKQTDLTFNLVTVIATIGALMGVVISYYILRTRPVYLVDFQVYRAPDSWMATYTRFMAGSRKCGRFTDEALDFQEKIMTRSGLGQETYLPPAVQVVPPECTMENARKEFEMVVFPIIEELLQRTGVHPKQIGILVLNCSLFNPTPSLTAMIINKFKMRSSILSYNLAGMGCSASPISIDLAKQLLQLHPSSYALVVSTENITQNWYFGNDRDKLLPNCLFRVGGAAILLSNRRRDAWRSKYELMHTVRTHLGAKDEAYSCIFQMEDQERNIGVRLTKELFAVAGEALKINVTTLGPLVLPLSEQLLFFFNLVARKVFGYRGKPYIPDFKLAFDKVCIHTGGRAVIDEIERQLQLTNDMVEPSRAALYRYGNVSSASIWYVLAYLESFNGMRRGDRIWQMGFGSGFKCNSAVWRANRNFKCLHQAWEGFNLEEMRAHLASLPNHHNKKGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WM85</accession>
    <name>A0A835WM85_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">CCHC-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_005466</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449310.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WM85"/>
    <dbReference type="OrthoDB" id="5418639at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.60.10">
        <property type="entry name" value="Zinc finger, CCHC-type"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001878">
        <property type="entry name" value="Znf_CCHC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036875">
        <property type="entry name" value="Znf_CCHC_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010666">
        <property type="entry name" value="Znf_GRF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33680:SF1">
        <property type="entry name" value="OS05G0489500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33680">
        <property type="entry name" value="OS07G0190500 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00098">
        <property type="entry name" value="zf-CCHC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06839">
        <property type="entry name" value="Zn_ribbon_GRF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01228">
        <property type="entry name" value="EGGSHELL"/>
    </dbReference>
    <dbReference type="SMART" id="SM00343">
        <property type="entry name" value="ZnF_C2HC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57756">
        <property type="entry name" value="Retrovirus zinc finger-like domains"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50158">
        <property type="entry name" value="ZF_CCHC"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51999">
        <property type="entry name" value="ZF_GRF"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GRF-type" evidence="7">
        <location>
            <begin position="172"/>
            <end position="213"/>
        </location>
    </feature>
    <feature type="domain" description="GRF-type" evidence="7">
        <location>
            <begin position="323"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="6">
        <location>
            <begin position="408"/>
            <end position="423"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="6">
        <location>
            <begin position="457"/>
            <end position="471"/>
        </location>
    </feature>
    <feature type="domain" description="CCHC-type" evidence="6">
        <location>
            <begin position="523"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="264"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="471"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="37"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="81"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="279"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="291"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="474"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="502"/>
            <end position="511"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00047"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50158"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51999"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2449310.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="541" mass="52099" checksum="92232D53DB40B5B0" modified="2021-09-29" version="1">MACHPDDEDYGYGGPDVDEDFDQIEQRPPPAKALPSNAPSSNAYGNNGSAKRGRAPDEVPDTADQRLTHHNPYLAHDNGANGHQDQQPASNYEEGYGAAPYQQQPSKRSAGGAPGAQYAQPAPDPYGQYQHPPAADTANLHNNGPDAGVNGGGSSPYGAFAASGPNGEPVPCACGEPAVRRVSNSANNPGRAFFKCAKGIGQQCKFFKWEDELAAGGGTQGGGGAGAGGYGGGARGGAASMYGSTGAGAGGGARPYGNASNPYAAGGGSSGSQAVSSSGPGGGSRAGGAWDGAAAAPHMGAYGDPNAPPEAEGAAGEQEVVKCGCGEPCPVKTSNSANNPGRQFFACPKMRDDPTRCRFFVWADEMDKNGGGAPGGGGAGGYGGGGGGYGGGGGGGGYGGGGGGGGVCYVCQQPGHFASACPQKGAGGGGGGGYGGRSSFGAGGGGGGGAAGGDRPCYLCQQTGHWARDCPTKQGGGGGGGGYGGRGGGGPPQSFASRFNRDGGGGGGYGGGGRGGGGGGGNCYKCGQPGHWASQCPNSRG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WMX7</accession>
    <name>A0A835WMX7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_004904</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552876at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052812">
        <property type="entry name" value="Plant_DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44272">
        <property type="entry name" value="DNAJ DOMAIN (PROKARYOTIC HEAT SHOCK PROTEIN)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44272:SF3">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="15"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="551"/>
            <end position="583"/>
        </location>
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            <begin position="584"/>
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        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
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            <begin position="1093"/>
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        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="1">
        <location>
            <begin position="1126"/>
            <end position="1159"/>
        </location>
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            <begin position="169"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="301"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="612"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="795"/>
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        </location>
    </feature>
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        <location>
            <begin position="843"/>
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        </location>
    </feature>
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        <location>
            <begin position="1173"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1289"/>
            <end position="1317"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1333"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="185"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="202"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="231"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="324"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="368"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="386"/>
            <end position="397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="398"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="439"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="461"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
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        <location>
            <begin position="795"/>
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        </location>
    </feature>
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        <location>
            <begin position="843"/>
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        <location>
            <begin position="917"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="966"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1178"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1333"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1375"/>
            <end position="1393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1396"/>
            <end position="1411"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2450401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1550" mass="152141" checksum="E5B4735629A66EFB" modified="2021-09-29" version="1">MAGSKKKKSAPEGPDLYAELGVVRGASTEEIKKAYRRLALQCHPDKNPGDAAAHERFQKISVAYSVLSDDGKRRYYDQTGTTEGLDISPDEFMDMFQSLLLEIIGGADMIRDMLSCFTPKELSRLPPFPFPKELFPPGTFPEGLRFSSKGLRGMPPQVEEMLQSGDLHAMFGAMGGSPAAQGKAGRGRSHGHGHGHGRHRGAGGAGGSGAGSAGGSSAGGAGARRGLFGPEVGGGGGGSRRAGRGGRGDAAFGPFGGGMGGMGMDGLGLELEELAALAALGDLGDLGKLKGRDLEALLGGLSAAGGRGRGRPFGDFGGAGGDLGGDDDDSEFDDEDDDEDDSDSGSEWTDVSEEELEELWGLKGQGRQPQQQPPQQQQQQEQAGARDGGSQAGGGSWRSGAGARSGSASGASSSKGDSSGGSSDSSSSRGRHSQQGAGTSTTHSSSKPGTARGSASGGSAAGAATAAATASSSGPQVGGAATAAASSSAPRQPPHQQQQRQQHQQQQHQQPALPPSLVKEWIAAARGGDVGVLGVMLGAHPGLLGARCSGMGHSALHWAAAKGEVEGVEWLLRQGLDVNTRNDDGATPLHAAARNGRMEAVEVLLAWRPPQPPAAAGVASTSTPGASLSASATASAGSGAAAGAGSSSGGGGSAVGGGGGGVCDVGAVDGEGRTALDLALEFKHAQVADRLQRAMVSAQAPTASAAPGAAEASAAAGSSPAAASAPSALEAAAQGQQAALAAPEAAAAAAAAAAAAAQTTAAAAAAAAVAASASTSGHVSSSAAAPPTATVNAEAPLASAHSSSEAEAPVPPSVPTASPSSDVTGSDSNSAAAIATAAAAPATVQAPASQSEPTAAVPAAEPAPSAALSTTAAPTAPSTTAAPTAPSTTAAQTAPSTTAAPTAPSTTAAAGGPGHRAQSADTASTSATPPAATTRASSSASSSQQPSEQQQQPQQQPQQQQPPPQQQQQQQQPQQPSQATAPLAAPAAAPAAVGSGGGGGGTRAPLSAEQKAARRAALLAADEAAEREEERQEAARAAAAEARARAAGAAGREQGRAWLTAAQRGDLPELRLLLAANPRLICYQGQGTSLSFTAHSALHWAVAKGHTQVARWLLEQGADPDALNASDATPLHTAAGQGAADCARLLVVEAGARMGVQDGLGDTARDILLRRDAQQLPTGSSTGSSSSGSSGSGSSSSGSSGGGLQLANELELLARVAAMRDAPGGEADWAPRAMRTVLAAAGINTAGMLERQELVVACRQLIARHPPRIRRPPPAAAAATATAATAAAGASTASQAAPASGATPPRPTPAHAAASSSAVAAAAEEAASAAAASHSPAAAAAGTRQQSGSSTAAPAAAPPPQPSRQRPARPASPPDSDDESHDEDDDNDDDDGVETSGEPASDAAAAPAAAAAGSNAGDAAAAAASEAAKQRGNEAFGRGDFAKAVSHYTMAIRLAGQPNAVLFSNRAAAYCGMSYFGKGQADAEEAIRLDPAQPKYRCRQGVALLGQLQLREAAAAFTAALKLDPAYPAALQGLADVRAAAARTNGGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WMZ0</accession>
    <name>A0A835WMZ0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005172</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449640.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WMZ0"/>
    <dbReference type="OrthoDB" id="547262at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030149">
        <property type="term" value="P:sphingolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393:SF6">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="509"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="623"/>
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        </location>
    </feature>
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        </location>
    </feature>
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        <location>
            <begin position="542"/>
            <end position="557"/>
        </location>
    </feature>
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        <location>
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            <end position="641"/>
        </location>
    </feature>
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        <location>
            <begin position="656"/>
            <end position="667"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="708"/>
            <end position="720"/>
        </location>
    </feature>
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        <location>
            <begin position="721"/>
            <end position="735"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="853"/>
            <end position="863"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="916"/>
            <end position="945"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449640.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1209" mass="125155" checksum="888449B68BE47934" modified="2021-09-29" version="1">MPRLLLGPAAAGRSCWAKLPHDVLGNICSRLTQNEVMALALVERATRAAVAKLGYPSVFRLSLPVPPALFSRCWAAPGAFSRLTVAKRKRLLCLLATSGSLANLQFAAERIGLHQPLTHVGVLCAAAEAGHAALCKELLNAREAAQVGGEGGWGDAAVGEALAAGGLFPTLKQWFEDNSLRGGVSNSRMLVAAAASGHLYQFAWLVRRLGLRRRGLLEAGGGSDGSDTPDTAAAAVPGLSTRPPQGGLLLLRNVLCAAAAAGHAAFVEALLPPYGAAASLLYPLEDQGRRREAVWQQRQWQPQPTAAVLIPELLPELLLVDAYEDEARQAAAAEAAVAVAGLLRAVGGPAAATAAAGGSAAGAGSGAAATAEVPGMAVVSDGGGVVSPAELLLGSVVARDVLAAAAKGCDLKGLQRLHALLGRRAPPRSPALSRIDLLARADEPDAAVLAETREAAAAAVLAGAAGSPTPDWKQKFEWLEAAGNVPPPGPAGRSVRQEVVQAAAGLRLHQRRRGSQHGPECGCEGCGLRRRPEERPSGRKVSAASAAANSAAAGAAAPCPRLESGQEALRRVMWLERRGYRAAPEPQRADGGAKGLDVGSSSGCLAVNQAALAGNLPVLAFFMGPPQSSQRRRPEDKKEPPQDQQRCLAANAPAAERQEGMAEKEPAASKPKGMAPLLPPASLAALYREITPVVELEPQPLALAEPHPLAPAEPQPPKAPQPLQGQQELLQAQPRPQRRRRLLPVSEEQLLRALASGGQLASLRWLHGWAMARGRSCRLHEVLSAGPLVRSLLAAALADAQAETAHWVMSVLLLGKADAPLRPYHPADPDSAATGVTAASMPPASASLGQAPAGGARAGAGARSRRASSTVSLSASLSASFHHLSLSAATDALHRISASSSSSSISSSTHGAHPLAPADESAATTTTTSPAADAARAPTSTQAAPLPSPPPLLATPASSSKPICAQLQEDEHRSARTVAFSAANTEGDRAAEPLDRALSLLRQLHTQGSGLFGEQLMKLAVEGGCVPLARLMRLPEAGFPWDEEDAWTAAANCGSADVLLWLQEVGCKAERSSLPVLAAASNSDLATLQRLRAPPLSYPVDWLRLGGTVADFHGDDTQLQMLLVAEAEAAGAEAEAALQRGLATGLFGIWEDTNAGCGYRAWRGLKRLMCCGGASRRRRSLTRKCLACMQMSALGCLVACCYPCIAAQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQA0</accession>
    <name>A0A835WQA0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_003970</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451368.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WQA0"/>
    <dbReference type="OrthoDB" id="548247at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="172"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="258"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2451368.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="328" mass="33220" checksum="2A7452591BCCF81E" modified="2021-09-29" version="1">MSILPVHNTCQCSTTASTSGAGAAQFSARQCQAGARRPSGLPTPELLSSRARAAVCARAASDWSGGGDGRYIPTDWSGVAPGAYADPRVAPLGPQQRPPYGPGGETGPSAGASTNSFDGPQDSDPLSEIARSAVDAVTGCLAFLVGRLSDAALSLLPSHVKRRAVENTVKGALALLGLALLQSVLSLVLTVGTLVLAVYAAYQVFGVQLPFLPPQPGSGYAGGGGAGGYGGSYRQDGPFASAGTQVDPRYAGTGGSYGPYAGPYQQQHPQQVPQQHPGGPGRYGPGPGQPYPGGYGGAYPPRPSGVGGYGPGPAQQRRQGPTIDVYWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQB2</accession>
    <name>A0A835WQB2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_003706</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451932.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WQB2"/>
    <dbReference type="OrthoDB" id="26525at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050145">
        <property type="entry name" value="Centrin_CML-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23050">
        <property type="entry name" value="CALCIUM BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13202">
        <property type="entry name" value="EF-hand_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="69"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="107"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="183"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="15"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2451932.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="244" mass="26475" checksum="C9D9E161AA7B7D83" modified="2021-09-29" version="1">MGAGCSSEHGVATNAAPVAKAASVKSQPAAEATTPSPAGTPPAASQPSRASVDDFLEEEDTPAKRDPEARLEALHRCFDALDKDKSGTIDFKELKQYLFKTGVNISLITGKAEELMAKMDLNSDNLISRDEFTHMMEALLVGKTDEDLEVWVAEVVFTATSRNVVGFGDSLGEVLSGLDLTTEQVSTLKDCFKQLDRNSSGFVELPEVKALLGRSGMDMEHVSEELNTIMLKLDKHKQSRKDKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRA6</accession>
    <name>A0A835WRA6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">SRCR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_003080</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452042.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="539570at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.200">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.250.10">
        <property type="entry name" value="SRCR-like domain"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013320">
        <property type="entry name" value="ConA-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024616">
        <property type="entry name" value="Pherophorin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001190">
        <property type="entry name" value="SRCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036772">
        <property type="entry name" value="SRCR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002889">
        <property type="entry name" value="WSC_carb-bd"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48071:SF18">
        <property type="entry name" value="DELETED IN MALIGNANT BRAIN TUMORS 1 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48071">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12499">
        <property type="entry name" value="DUF3707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00530">
        <property type="entry name" value="SRCR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01822">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00258">
        <property type="entry name" value="SPERACTRCPTR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00202">
        <property type="entry name" value="SR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49899">
        <property type="entry name" value="Concanavalin A-like lectins/glucanases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56487">
        <property type="entry name" value="SRCR-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50287">
        <property type="entry name" value="SRCR_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51212">
        <property type="entry name" value="WSC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WSC" evidence="4">
        <location>
            <begin position="458"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="3">
        <location>
            <begin position="587"/>
            <end position="691"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="3">
        <location>
            <begin position="714"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="3">
        <location>
            <begin position="831"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="134"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="396"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="942"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1122"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1185"/>
            <end position="1218"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1370"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="137"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="396"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="947"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1130"/>
            <end position="1156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1370"/>
            <end position="1395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1403"/>
            <end position="1439"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS51212"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2452042.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1762" mass="185977" checksum="BD34D144DE686739" modified="2021-09-29" version="1">MPPLVSLERPHGFVWAVTSHGPVLPVCQAGGWDDTASALVCRAVGFPGGRVGKAVMNLRRQLTAMVTNVTCAADAVSIGDCSGILMEYGRCLRLAAVECNWEPPASLAPQSALFDAYEGVVTTPSNAVTAWADARTPRQQPQPQNQTQTQTQPPLQLTMSGTCLYDNSSSSSTAAGDVSGGGGGGAYGSVVFDGRSCFGRVAAGANLSGWSSERTAPFTLLAIANLDPPASGNSSEPYSVIHISRTPSDFDFEAVFDLATRVNSTSTSFLYDSQAGQLAFGRLELPASYGEWAMYAFVRQPGGTAAAMYRSSQPRIGGARSFGGGVELISSQSDQPAVSIQPDNLVVGANWRDGNHYLKGRLAVAAVYTSALTNDQLNDLYNLYAPRFGWMRVAKPPPPSPPSPAPFAPHPPSFPAPSDAVDAPPPGDVDTQQAPMSSPPPFPSGGARPMWPISIIARDTYVGCFEGDPRYGVSEASPAALLPYTLLYDVGNLTAELCADAALAGGFKAYGLTDGSTCLAAFDPEPARALAGVPPEGECRSLCSGDRGQACGGDGSFDLFLVGSYLDAKLDSGRSPAGGRDGSYLEVRLSGGFARDAGRVEVRLEAGGPWGTVCGLPSFGDAEAGVVCRTLGYTTGVSVFHPATRSTAPILMSGVSCNTSAHSQLSECTTARGAAADRTCTHANDMGVRCFNLETKALPEIATSMVPHSWSLDTQSWGGQIPVEDGSVGYVWSYSPAAAAWLPVCHPGAFDDTAATLACREASFDSGTVLPYDEWGVASLGFLSQTQVLRDVRCVPGASSMAGCTGSLAPMAMCRSLVTVKCSYDTPDLSLSLEDSPEGDPKTGRVEVTLEGDGKPICFDKSLLEPTNPVAGVLCHTLGYHGGGRAAAGPRELNTTNTAGWLTGLDCPPDAEWLSQCSYSMVDYSQSAVAEQCRSQRPLQLRCFDTAPPPAPPAPPPRPPRAPRQPPLGPRINAQQEKNKDTCVYVRITKRPPFEYDRYQEPLRIPSSKCVPFTSDIAREINMAAFEAGVKVLRPFQDVLDGCNGLGIRVCGLLEGLNQRGWSGRGGKPVVDLPKLAPFFSSALPRWIDRVFGGPGCNRTSLGYGVSAFLEDSNGEVQFTSTRTCTAVSSPPPPPPPNAPAAPALPPGAVPSPAGPPDAEQPAGAPPAIDYSCRGCVEIVMTPREGTLEAPPPMEEPPHNGLDPSPPSPLASSSPTTLYGNGWPIDQEFCRTAAAEISTAINRAANDFRAIWDEPFRLTECDPNPRRPLLRVCGRLGFVPVQLEALLQDEAQGPRTWLQPYMMQYNPYTYDYTNQPEEELCLPRFRHPERREHMYDIVVRMVSNDTFGMQCLGNASYDVSCAIPDSDYASPPPFPPPPPRVEPSVWRPPAPPVTPDAPKRPTRPSPPPRPPPSPPPPTPPPPPPPPPPRPPPPSPPPPPPPTCQICATLEYAAGNARFAFARPTHCAAFTAAVSSVMTQIATGRVDFATAWPTAATPPAVTCEATRITVCNTLTSRGAGIRIRDQLIARLEAIARAADGICTASPGIVFTAAVQDGRASPPPPADASCFPVVPVTYNCSLPAYREFPFRPCVAARNATAFVLDKVAPDAARANTHCFYFRNNTPASPGGVCASASRLTGVLFRANSTARARVRTVFVENGADRSARPALGLVFNNNDTILNVAVPDWGVPTVSNPAAPDPSRPRVCIQLDPGVPLSQFCGAGGASAVGGCALNIQTDVGDTCCPVQPYTPPAQAPTTGRRRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRC2</accession>
    <name>A0A835WRC2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_003055</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRC2"/>
    <dbReference type="OrthoDB" id="537338at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.30">
        <property type="entry name" value="TolB, C-terminal domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011042">
        <property type="entry name" value="6-blade_b-propeller_TolB-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044515">
        <property type="entry name" value="ABTB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231:SF1">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="484"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="151"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="320"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="320"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2452014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="676" mass="69355" checksum="01544B8BB4EEAF3C" modified="2021-09-29" version="1">MGRKLCPLLGADGRHGCGFELGEPLRLFRQPSTAAPGGAGLLFGGSADRQPFDTGCFNIDTCVWDSWSASVFFKSGFAIFRLVGDMVTLVAGDLNQRGYADGPGPAARFFRHGVCVAQLASDGAGSIVFVEGSCIRRIQLPAAWRAAATTQPLAHPHTAPTAGPRSSTWGPSGAGSTATVAPGATVAASAAAGAAAAAAASAAVHGDDDDEEEGEPVAQVSTLPFLLGRTVHSAVCVLQPQLPPAGTAGAAACTGRGAGSAGWLVLGTTSALYRYPLPLPPPPPPPPVPSPAAAAAGPAPALAPAAAARGRAAAAMAAAAVAGPQAAPHQQQQPPPQQPPPQQPQLFAGNEGETRQQDGRGAKARFRCFHGITADAAGCIYLADTHGHNGTHSCVRRVSLDGHVTTLASVPANCWFPTILPNGQLKLVDFGLQPLLPMPSAAAAAKAAAAAAAAMKAAAAGLPPPRSLPADLGALLDAQPDDSSDLVIRVGERRFHVHRLILSSRCDYFKQRLAASGGFADGRAAELELPDADPDAFALLMRWLYTGGADIPLEHARGVAELADRLLLPELCDVALEAVGASVDVATIVDSLLWAAGCSDLRNGGGGFGELLGLLKGWYVAHYVEVAEEAGDSRARLAAEAPGLMVELMDAVLLRPRQQQQPLQQAGGRYQKRLRI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WSF8</accession>
    <name>A0A835WSF8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_002447</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WSF8"/>
    <dbReference type="OrthoDB" id="552576at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47852">
        <property type="entry name" value="OS06G0298400 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47852:SF2">
        <property type="entry name" value="WW DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00397">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00456">
        <property type="entry name" value="WW"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="358"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="149"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="414"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="630"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="982"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1103"/>
            <end position="1208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="18"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="69"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="153"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="430"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="441"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="501"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="706"/>
            <end position="717"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="718"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="729"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="751"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="784"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="831"/>
            <end position="848"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="991"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1005"/>
            <end position="1014"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1107"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1137"/>
            <end position="1148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1174"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1199"/>
            <end position="1208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2453117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1273" mass="123784" checksum="02B3004EF79D6302" modified="2021-09-29" version="1">MKRGRAAARKAAADSGSDGEPEREPLDPIAAAMEAKRLRLLEAASRGMPNAGEDRYLRPPRVDSAPDLQSAPQPMASAAPAPGPFTVVTTITRIPRRPAPAAAPAPAAAGAASGAAASAAAATATVGPAAGGVGDGSAKGGLAALLGYGDAAGSDEEDEEQEVEAAEEERLGEAAGTPRAAGAGCTAPVAEAATTSGAGPTAAAEAASGAQEAGQARPAAHQGDGMDTELASFMQELEASGLLEDGGAASGEQPQQEQPQPQEEQPQPQPRQQQQQPEATATDAAAAHGGTGERTAGAAAAAADAEAPAADASAAEAASANQHAAGGAGAGAAPAATGGGGGGASEEQQLLGYLVQAPEWCKCLDGGSGRTYYWNLTSGEVAWEPPGGADPDQLLPPPAGAEAAGAGAAVAAAGAAEGEAAQEAAEAQEAPADRGEPTQSAGGEEPAVAAGGEAAEAAGPSAPTEDGMDVEAGGADDSAQQQQQQQQQDMNEATDPDTRQAAAGHATSSGDAATTAAAAAADGEQAAAAVELLQAVTDMVLRPPQPHIHQVMAALEAEAEVAARGLLEGLPPLVLLAVEARVRAADWRALAAQQAAAAAAGQPAEAVTWPALERHMVSAVRRLLEALPQARSEAERSRQLPGAGGGGGGKAAAIAANAAASRSGAGASASAAPVPAAAAGAGEPAAVRGSDAGGKLPGTGGASKSTDAEREATEREAGAAGPDPAPVADMEEGELLEDAEQNQEAGRQQGPDAPRPSAEAPEAAETAGPSPAALPPADATPASVLPPLPGSPPPPPPDAGPPPPGSPPPPPGSPPPLPPEAPPPPPHAADTEDGSDDMAIDDDDDDDATGNAGTAAAPAAAAATTTAHYYPHYAHAAGAVPGAAGLPPGFEAAATAYASGAAYGASAYDTYMSQAYGYAYGMPPPPASTPAGYEALQYVNSYLGYGAGAAAAGTDAAAAAPGAAAAAAGTSGAVGAKSAKEYRAEPVRNPEAAAGAEGAAEGTPEPQTGRVSASPTPPPLDLLNMHAAAAVPDTAAAMAAARRKAAAAGAVLVGGAAAAGGGGGGGAAAGSKKSKAGGGGGGALTGKMGAMLQKWSAAQREIEAEEEKAARKAAEAEDPNALERKRQAEVERWKWEQQVTGAASSNANFAPLGDWRSRFPKMAEGGGDAAGAKKEKKEKKEKKEKKEKKEKKSKDKPDAGGAADAAAGATAAVVAGGGGGSAAGSSAVLNSKTRPDLDALSLGLPPGWRAMWDKSSGDVYYGNLATKWSARPG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WTF2</accession>
    <name>A0A835WTF2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Phospholipid-transporting ATPase</fullName>
            <ecNumber evidence="7">7.6.2.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_001535</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>ATP + H2O + phospholipidSide 1 = ADP + phosphate + phospholipidSide 2.</text>
            <dbReference type="EC" id="7.6.2.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="7">Membrane</location>
            <topology evidence="7">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IV subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.6.2.1" evidence="7"/>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453311.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WTF2"/>
    <dbReference type="OrthoDB" id="377733at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140326">
        <property type="term" value="F:ATPase-coupled intramembrane lipid transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045332">
        <property type="term" value="P:phospholipid translocation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000029">
        <property type="entry name" value="Phospholipid-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006539">
        <property type="entry name" value="P-type_ATPase_IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032631">
        <property type="entry name" value="P-type_ATPase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01652">
        <property type="entry name" value="ATPase-Plipid"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092:SF150">
        <property type="entry name" value="PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24092">
        <property type="entry name" value="PROBABLE PHOSPHOLIPID-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16209">
        <property type="entry name" value="PhoLip_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6 7" id="KW-0460">Magnesium</keyword>
    <keyword evidence="3 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-1278">Translocase</keyword>
    <keyword evidence="1 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="386"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="438"/>
            <end position="460"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase N-terminal" evidence="9">
        <location>
            <begin position="33"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="252"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="876"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="878"/>
            <end position="899"/>
        </location>
    </feature>
    <feature type="active site" description="4-aspartylphosphate intermediate" evidence="4">
        <location>
            <position position="507"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="507"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="507"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="508"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="509"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="509"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="618"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="663"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="687"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="724"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="804"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="805"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="806"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="943"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="949"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="968"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="971"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="972"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="972"/>
        </location>
        <ligand>
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR606539-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU362033"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF16209"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2453311.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="984" mass="107654" checksum="A171F036B105A813" modified="2021-09-29" version="1">MGWFGGRGGPAVATEAHRHIPLGTSLETEEHLAGHYRGNYASTTKYTLLTYLPKALFEQYRRVANIFFTLMAALSLTPFSPLRPWTCWTPLVIVVGVSMIKEAREDYKRYKQDREVNERPTCVLDRKSGKFVTVPWKALRVGDIVQVCRDQYLPADLVLLTTSSDEGTCYIETMNLDGETNLKIKAAPEETRCLEACDLAGLNAVIDCEGPNSRLYQFTGNLRLRPPLPPTVVAAMEAARAMAAAAAAAEGGGGGAELKPKAGEQQEEGAGPGWGRAAAKSLVANGMEAHAEVLRSTASTTARPGEGGRWNLRASVRRRASARAEPPQEYVASLAASALVLRGCSLRNTECIYGVVIYAGHDTKIFMNSTEAPSKRSYIERTVDRIILLFFFVLLLWCLISAVYHAWWTNTHFKRHWYMRPDAVDAASDPDSPAQTGAVNFFVALLLYSYLVPVSLYVSIEMVKVFQAMVLIARDRDMYHAETDTPALARTSNLNEELGMVAAVMTDKTGTLTRNVMEFFKCSIAGVAYGAGITEIERSNALRKGQVLDDRERPEAARYRERFFNFYDERLMGEAWYSAKDPATIEMFFRLLAVCHTVIPDGPTDVKSIKYEAESPDEAALVVAAKAFGFFFYKRTNTTITVRERTPCGTNDVEYEVLNILEFNSTRKRMSVVVKEKANDKIIIFCKGADTVIYERLDPNYAPNEDAKAATTRDMEDFGASGLRTLCLSYAEVDRDWYTNWAKEWDAGKKSLDDREAKLAEAAEKIERNLRLLGCTAIEDKLQEGVPACIKQLALAGIRIWVLTGDKMETAINIGFACSLLTEEMRQHTVTASSPRVEELEKAGRRQEAEALAAELVAKQLDKIDLELRQAAEAAGSKVGGGGGAGSKHGGGAGPGTGGGMGGDAVEAALIIDGKALSFALSKDLAPGFLRIGLRCKAVVCCRVSPLQKAQVTGLVRSTGSITLAIGDGANDVGMIQRAHIGEC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WTF4</accession>
    <name>A0A835WTF4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_002426</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453094.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="539138at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028089">
        <property type="entry name" value="DUF4455"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027914">
        <property type="entry name" value="DUF4456"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21444">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21444:SF14">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 180"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14643">
        <property type="entry name" value="DUF4455"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14644">
        <property type="entry name" value="DUF4456"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF4455" evidence="2">
        <location>
            <begin position="109"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="domain" description="DUF4456" evidence="3">
        <location>
            <begin position="1237"/>
            <end position="1447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="645"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1175"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1457"/>
            <end position="1521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1533"/>
            <end position="1593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="652"/>
            <end position="661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="662"/>
            <end position="688"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1090"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1183"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1486"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1549"/>
            <end position="1578"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF14644"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2453094.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1663" mass="174930" checksum="070CB197B6221F80" modified="2021-09-29" version="1">MDWEKKTVARSSLREAAADVFNDTKTPGQALLSALETAETIRKDRYSSTVAAKMKAAREYLPALEVRHPPRSDTTIFGKPGAEVASLLPDGRPRPVGKVTLDNVKAMMEQQMERHKQALDAFVGTRDEARAELEAAVAAAAADFQAQLAADDAGIAEDMGALDDDMVMRLTEQEVYQIWDCVAQRIPQRARWIEECAAALEAAEEHRRETVEAALVSLCAELNEAAVVSEGEVERLVEKEAMALNVAILENRRAYADVVHRLQVAEVEAERARRAAWTEGHRKWRTLRTQHAVQVFVDRIKSPEFAEPADRLAAFGNLRDRQAAVLSGLSAHWARAGAVTPPHLSAKKVAGWTADATALEAAWARERQQLLAGFRAAEDALHVRATALLATLRDEVGEYQGYPPEELDALVAGSAGEAVAARRAAALEMLAAAETFLDEQAAGWAAVSVALSAWLNRLCTMYDEHRRLTGSDESDVRGGLKAAREAFNAADAEREAALDAAVAAVTRGSGEAALDARVAEALKRLDDIEEGYRGFHRDMTARAHAYPARVRSANETYHVLLCDQLGCQPQTSAAGWPSLSGGGKKTLGHIKLPDGRSFAVVTDMLQHLLHPEEEERRAKEEKAAEEAAAAAAAAAAAAAAAAAAPPAPPASPLKGAKKGAAAPPPEPPPPPPPPPPEPEPTPPPPPAASPLSTAGTPLCRTIAMPEDVLRRTIESIQSGMLSDMMTFCQRSLEAAEDWSAEREVALTEELDSWLRHHRPRAGRIEEEVRMARSVELVAQRRRVELHLKAQSTAVKAQAAAFEEGLRTLESEARKGVGRLRATEGFLGQCLSSKAIGIRQREAEALRVRLDKELTARVAELSEKTRAAVARITDANRKFESDELKTFEAGGQYADENAAAYKRSLGAIDAHMDRAWAEQQGRLEASRAALAGEADSSLSVVVGLVPSHLEDMALLEKMDALVQGARRKAAGELERNKATAADITALLDQLDALLDGRKAPTAPPRRRRRSSGPAAAASAAAGGRPDSPGASSVASSARPGSVGGGGPARSVGSVASMVGPAGARSSPSAVSMQRGSPGGGGTASGGAGGSPPGRRGDGKPPPPAEVPATPLERCRAILECTDSLRKALLRQAKVLDFLQSSGLVAPPVDLRIDAAGVDPPPPPLGSPEALATIAGASPGGRPGSTLTSAKRATTPSNGKPGTAGAGAAAAAAAGAEPPAVKLAVDVEAVIDACKKETEAVAKTYYAAKEKARPIRYPARIPGTVEELLRGTDSVLEGLRQTTLSHVTEAVKELRTQVIRGYRSLERLPAVALALLCEHEVGLLGAAHGQLVSELEGRRGALLKLVEVHRGSLHPGMMMPARRPELAAVKSSEADRAAAHAALLATYGVQAVDMARRQAPALQGRLLRLAAQLAALLDTFIMPQDLPPPGEGDSWVYDLPHKDTKQLLRLALAQAEAEVEAAPPAPAPAPAEAKGGKPGAGAAAKPGAAGGKPGGAAAAGGGGKGKEAAPGPERPYAPGEWALPAGNFDLVSLGWLDEEGRPPHGVPQLPPETAAAAAPTKAAAAPTKAAAKPAPAGKRPPSAKPEAAPVPPGRTPLVPEPAPLVALDTPCHRCVVRAYRAAVQRLEESLRHSMSGHRLRLSSWAKDEELWGRTWAQLVGRLEGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WTF7</accession>
    <name>A0A835WTF7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_002688</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452446.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WTF7"/>
    <dbReference type="OrthoDB" id="552281at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2452446.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="262" mass="26325" checksum="4DB507939A8783F3" modified="2021-09-29" version="1">MRQRILAVLDAADGAAAVGGGCGGEQPAAAAAWRATVVEKLLAATDANDLDLMLQHPVLLLAQAEEYRRVLLLQGEGGLASHTPAPLAWEEMQRAAGGGLEGLPIGYQAAASAAGAASSAAAQFASAAAALSSMQRLPLLPVSKPEQSPATEDSIMPMLLTTANGEGVPAGVTSAHVAEPGNSALALPLLPPAAPKAAMLGRRALLSTMLRASEECGIGKELTAAVTPLSRAMVVRDAGADGAGEASFDPGPPAPLMLYELD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WTG0</accession>
    <name>A0A835WTG0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="2">1.3.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_003277</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="4">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="7">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="5">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="6">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the Dus family. Dus3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452250.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WTG0"/>
    <dbReference type="OrthoDB" id="259935at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.1000.10">
        <property type="entry name" value="Zinc finger, CCCH-type"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25585">
        <property type="entry name" value="zf-CCCH_DUS3L"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="3" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <keyword evidence="8" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="10">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="81"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="8">
        <location>
            <begin position="121"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="18"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="263"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="20"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="263"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="306"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="343"/>
            <end position="354"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2452250.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="528" mass="53102" checksum="96E52E3499BBC164" modified="2021-09-29" version="1">MLARNIVPVKAEFLIRKSAAKPSAAGPEAATAGANGAATGAAAQDSTAAAGGKAGESNAAKSEEQSKSQGRKQMRKDVKAGRGLDLCSNHALGRCTYGDGCRFSHDIGAFIRSKPADLPGNCPFVAATGECPYGVTCRYARSHTAPVCDDANHQLLATIPAPPPVALSAPLPSTVDVPGGAVAPAAAPKEEGNAEAGAEAAAGAAGDAVAGPLPLPLPAAGGMAKEQNVMKKDVQAQLWKNRYDFSRADGMLKEMGLRISFKQGGGGGGGGDGGGGRGGRGGGRDGGRGGRGGRGGKKGQWQQQEQKQEQQKQAEQKDAEQKEAEKQGDVAMEGDGKQEAMEAEGAAGEAAAADVAEDDDTREAKRRRTEGCGGSEAAEAAKATAAAPAAPKAAAAATGSDAAAVAALSASADEAAAAAAAAAERVEAAEGSAGVAALTAKVQPGERRKLDLRGKTYLAPLTTVGNLPFRRVVKGLGCDVTCGEMALATNLLQGQASEWALLKRHPCEDLFGVQEGWAMGVGAMRGYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUF1</accession>
    <name>A0A835WUF1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_001488</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10690355at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070971">
        <property type="term" value="C:endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007030">
        <property type="term" value="P:Golgi organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070973">
        <property type="term" value="P:protein localization to endoplasmic reticulum exit site"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402">
        <property type="entry name" value="RGPR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13402:SF6">
        <property type="entry name" value="SECRETORY 16, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="140"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="665"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="693"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="774"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="974"/>
            <end position="1013"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1429"/>
            <end position="1463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1590"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1639"/>
            <end position="1784"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1824"/>
            <end position="1855"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1483"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="667"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="777"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1594"/>
            <end position="1619"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1639"/>
            <end position="1651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1690"/>
            <end position="1704"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1732"/>
            <end position="1741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1742"/>
            <end position="1754"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1836"/>
            <end position="1855"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2454469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1855" mass="183456" checksum="5B1A25C342270DD9" modified="2021-09-29" version="1">MELESVFRALFEVNGSRHAAIEALEALSVLAASGAPNNELWSKEGLAERLVSLLAEPWPAPGFGARELVSVPSIRRAVPGERGLPAVQLDSSIAAAVLCARLIATTAASDEPGPRRLAARLREVGGLAAVAARVRQAHDAQSYGGGAAQHPAGRPPHPHAHPHVFVSLLRALDALLRSEAGRIYYSERAAASGAAEGSLDVLLLPLQPPAPNPAALQQAVSCLKHLLGLEYRRAQKQQQQQQAAAAQAAGGIRRGDSRRLHPALSVAPGRHDPAVQERQEAALRRLLDSARNAALFLLRAVPAHMPLLLPLLPRAPSLCSTLPSASSELSAWQAALELVSTVCVSRPAVTEVAVDYLLSSAAPPAPRPASAAPFSGGKGSGTAGGEAAAALEWQVRCSYRDALQRALSQIVRGMACGLTRTLEDAAGSGRLLGESSRGPSTSGGVAASAAALAAAAAVNVHAAMHGSTPAAVSMLGGSSKMRLSLLPLVAEESAADMAAAAVAAAASPAASARQQQQQQQWHQVPAVTAAAAAVMSAPLLNSANESIMGADGDAEAEHGAVSGLSSLSAAQLPPLLLGPESSSVSVVLESQAATAADGHLSFYRLRLLSDVAARLLARLGRGEVLAATASRNGDGGYSAGCSIGAELLEAEVDAVLSSLESDMLGGSSSGRVGGPGSGEAVATGAGASGGLLGRRVSAGSGSSSPSPRQGQPPQLQPLPACGVILVFLSLARGHMQASNRQEAGILRACARRLFDPWCAAVAHLATELRELPPPTAAAPQAQQHGPEAAAAAASRPAGGALKSLDSFDDIASAASDGDAGGGVCSGGSSRVLLLPLQDMGRTIRARAAAAAAWELRAADYPWLMDGGAAATAAAAAAAAAALPLEGAMSAGDVRRYEMLLQAACGLMAAGGAAGCGEVQHGAWTWCCNLLTHVFKGENDAAAEAALYTDASFAGLRAVGVACLAECLHLAQAEPPPPPAPLLRTGGTAVGDDRAAGAAQSPRPEAPATKPKPLLPRDDAFVDCLQRLCTVAGNLSRHAKPAAAAAAAKYATAAPAADLAVALKLAAAAVRSLAGDRGEWRLKAACGALHGLLTGTHRPAAAAAPAAASAAFAAGATAATAAATAAPASPAVYGPAVAAVAGSGAAAAFGVRLTCLKPDQAMSGEELAAAGAVQLLLREGGGAIRDQIQSLGLLPWILDRLSRLAGAEAAGGGAGGRAAGTATAPVGQQSKAQALAKAHQHQQVAGLTLLLQQLLRSSQGGSTAEGASEAAEGSAEAVAEVVAAPGVLDLLKAYSGQSGGADVRTAGDAARGCLLALGMAPPEAPPPAPAKTAVAAATAAPSIDAAAPGTPLAIASEQQAATRTATALAHPQAVVGATAGEAVALYVGPVQKVAAVAAAAESVTAAVGEEEVGALRRRVEELEAGLRQLKQLRQPQQTQQPVAGSAAAKAAEGPQKQQMSQQGEEAQQLCAAAAAAAAAAATQHAEVTQQQQEQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQQLLLLLRTEVTALRAANALLAAQVSDLQRGAAQAAEGVAALHHTVAALLQQQPRTSGGGGGGPAAGGVGGSVGGGGGGAGQLKAEGSGGSYGGGGGGGGGGGGGGGGGGGGGAAARPQPFTSTPLGQTWGHMPQAATATGPGPGPAMPALHRTSHHKPHAAQHAQHHPQQQHAPHSPHRALLGVQEESSTSSIGSGGSPGGGSSSTSILPPLLPLSQQHRVSGTGMGSKGPSQHATSGGGGGVALLGSPTTPGAAAAAAAAALGGGSGVGGGAAAAAAALAATKTVGTGASGGGSGRATGATAAGAGQARRAVAATH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUJ6</accession>
    <name>A0A835WUJ6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_001030</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2453985.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUJ6"/>
    <dbReference type="OrthoDB" id="546153at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="20"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="97"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="224"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="430"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="106"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="233"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="270"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="280"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="452"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="464"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="483"/>
            <end position="494"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2453985.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="592" mass="61058" checksum="52E30AD9DA057CC6" modified="2021-09-29" version="1">MFKLLALHDETDPLKVLKNQSKRAQKRLQQREQSRLQPARGSDDDEWMQGQGATRGVESTDNVAARLFDELLGDVPNAELDPALLEDISLHMQQLGLARQQHPHPHQQLQLQRSPQPHAQGLGGRSPVPASRPGGGYGGAALSLTSSPGGPGLGPGPGSNPQQQRSNSGYYQQPHRPGAQQWPSLTRGASPPPSRPTHAELEYSLLQLFSGGGGGNGAGCAGSGAGGGGGGSHSVSRPSTASSSHDWGSQAGSVPAEDFPSLARAVGERPAAAAAAAGPAKRKARAGGHHHRTGMPVGRHGPHGTTAGVKVLHAARPHGGGGAGGGQHGQQPANGGADFNLRLLWELLGSGWCLLEDPLADDGSGGAAGGAGGGPGAGGLGALGAAGPDAAAAAAIRRLVAAQLAEQEDGPARGISQEDMIAMMTRAHRRQYTGAGTRRSRRPQQQRQQRGRSGGRGGHGGGGEDGESGSGDGDESESGSSGDEAHYYNSRDDSKSWRRTVDMMERSDWVRVTDTDGKHFKYRRLLPNGAIQTQTVCCSPSDAIRGVRNLQADLARKDAEANAVIKAWRQEQRLAKKAAAAAAAAAAAAAED</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVH0</accession>
    <name>A0A835WVH0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_000893</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2455069.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVH0"/>
    <dbReference type="OrthoDB" id="5034579at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2455069.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="172" mass="18624" checksum="689E3FAE037602E2" modified="2021-09-29" version="1">MTTSEVLSPPPPSQVASLAQPQFNVEALQSFPMPLVADVVNTENGDVASFARSSWHKESGKAGAFGLPTMLDMKAEALEQVQLDTWSAQPVDRGPAAAAPDPKLLRSWQYQVTGKLATAQVLVDVKAEHIKSGGPMGMKQEAIKHIMRHKPDDTFYVVDLANVQRMFKASPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WZ16</accession>
    <name>A0A835WZ16_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_000977</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2455161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WZ16"/>
    <dbReference type="OrthoDB" id="547828at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="207"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2455161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="234" mass="24153" checksum="3E96D96F17EC7C00" modified="2021-09-29" version="1">MQVQTRSTVSAARPVGASARRVSLAAVQQQVKQASTTAAAGPQEEIYIGFVKEEGFGDRTGRKGRVIKDDPRKYPSRDWVGVGGWAGGEAGLWQLREQVTKEKESKKPAGPAPSSPLPVKIPKAPAGKAPVYIGFVKEEGFGSREGKRGRIVVDDPRKYAGKEDLGPLAGVTGGFAAGEVGLKQYVATGDVKLRAPGQPGPKQFSPLTLAGAVALAGAVGGVVLGLVNDAAGGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3G7</accession>
    <name>A0A836B3G7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_008503</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000026">
        <property type="protein sequence ID" value="KAG2446512.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3G7"/>
    <dbReference type="OrthoDB" id="431068at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12232">
        <property type="entry name" value="RRM3_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="17"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2446512.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="225" mass="22942" checksum="FB2D735742A4250E" modified="2021-09-29" version="1">MAEEDERSSRRLNGKRSGALPSPLSAPTPSRMHLKTRHAQAIAHINPCLPIPNRSPPFLLFLNLLPHPIQILDDVRSEVVKCGAVVGLAAPMPPAHVTNADAARVYVKFSSADEAGRCRNMMDGRKFDDNSVRAIFVTEAEFLRAQAGEWVGKPGLLLDPAAAAAPALAGLAAPGLAGLAGLGAAAAAAPAAAAPAAGGLALPPGFTLPPGFSIAGALPGLGLPK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3J8</accession>
    <name>A0A836B3J8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Prohibitin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_008217</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subunit">
        <text evidence="3">Component of a prohibitin multimeric complex in mitochondrial membranes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the prohibitin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446645.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3J8"/>
    <dbReference type="OrthoDB" id="275637at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007005">
        <property type="term" value="P:mitochondrion organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03401">
        <property type="entry name" value="SPFH_prohibitin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.479.30:FF:000001">
        <property type="entry name" value="Prohibitin 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.479.30">
        <property type="entry name" value="Band 7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001107">
        <property type="entry name" value="Band_7"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036013">
        <property type="entry name" value="Band_7/SPFH_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000163">
        <property type="entry name" value="Prohibitin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222">
        <property type="entry name" value="PROHIBITIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23222:SF1">
        <property type="entry name" value="PROHIBITIN-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01145">
        <property type="entry name" value="Band_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00679">
        <property type="entry name" value="PROHIBITIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00244">
        <property type="entry name" value="PHB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117892">
        <property type="entry name" value="Band 7/SPFH domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="4 7" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Band 7" evidence="8">
        <location>
            <begin position="36"/>
            <end position="197"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004140"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009658"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU366048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM00244"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2446645.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="307" mass="33566" checksum="AE4795CFC319EA06" modified="2021-09-29" version="1">MAAPNPSQLAGALGAARSIANVVLFGGATLWAGANSLFNVEGGHRAIVFNRVVGIKDTVYSEGTHIMVPWFERPVLYDVRARPSVIQSQSGSKDLQMVNVGLRVLTRPNADKLPEIYRTLGTDYAERVLPSIIQETLKSVIAQYNASQLITMREVVSRDIRRILTERARYFNIILEDVSITNLTFSKEYTAAVEAKQVAQQEAERAKFIVDKAMQEKQSAIVRAQGEAQSAKLIGEAVKQNPAFLTLRKIEAAREIAGTISQSANKVYLGSDALLLSVGNAGGADGKGSELNLTEGTARRKAWYWPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4J5</accession>
    <name>A0A836B4J5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_007724</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000022">
        <property type="protein sequence ID" value="KAG2447397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4J5"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1005"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="784"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="311"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="443"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="481"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2447397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1038" mass="104652" checksum="0D735DA4A1B4CF6A" modified="2021-09-29" version="1">MNLAAHLAAPAGVNAKVLFPLLLYSCRLCASGRLAIRGPGAAPPESTLRALLRRHPLSSLVHVALFVSMLGATSHEVDARVELAACLLEAACALTCLSWHGAKVPGGPPHPAALLAGRALVPLVNLGLAYAAGRWRPAWGLLRAGAGGRKGAAKSAAKSEGLPAAAGQGPAQATDGSGLVRLTGAATAAAAQGVPEREHHAAACPWGSSSSSSSGNGGIGIGLCDRCRPRSEVAVEGASHGLPANAVRTPQQQGVSLPLPVTPGCMEFPAAPATPPAEEGAAHAAVHGSTAGAAAAAAGATGGVASQQQQQEEEEEEEEGAMAAQPPCLPDQQPSAAEAVALRMGMQQRTARRAVGGHQQPVYVPFLRVTTCHYKIPWAEPEDIAPGLEERLAALCATHGRVLTGVYVRAGCIELSFILAERAGNGQQQLPAGAAGGRGNRHLTADHPDGDLSELLRPEQLLAALGLLSPGSTTVSNGVPNTARSSASAANSTSSSGSASSRGSSIDASGGCSSDMPATAPGPAAITAAAGWRHPDARVLHIARMSSTQRNGPSVRARVVDVSPRVLLLPLPSIATDGAAAVAPAALRLRVAFSGGAGPAAADDVVVRCGSGYLAVRVAATQLSAADEGEAVGAQEWEYAVELVESPPHPQLLTVQLAFPAAAATAAAGAGDTHNALVQWLSVPVLALDDAAVAAELGAALLQQQVEQQDASPACMEELVCDLGQWLAAASGADATTAGAVRGGLPAEWVSELGAHLLEYAEGAGLVATAARIRAGAGQLAGDGAADMKNQTKQAKEDEPAGDQGLRRRGPLSKAAESDGKGAGCSGWAAGASSSPANGAGSTSRGDGLQEYTEAWIVTMCKTCQMVECLVALVLVIRGVKAGQTLWCAESAVTYAGLGMGTVTTLAGLWMTPRAWSRLALAARLPRFLGFMTSKFLLSAGALPPPAGAATYAGGPGILLLEGVILPSGCLLPPRTALLMSCLKLPLNLMSGLAVGAFAGPLPAALMALAVEAAALGTTLACHAYVRQRYVGINRRQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B5L2</accession>
    <name>A0A836B5L2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPIase cyclophilin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_007099</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000019">
        <property type="protein sequence ID" value="KAG2448073.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B5L2"/>
    <dbReference type="OrthoDB" id="532384at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46873">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46873:SF1">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032586982" description="PPIase cyclophilin-type domain-containing protein" evidence="1">
        <location>
            <begin position="24"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="55"/>
            <end position="173"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2448073.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="232" mass="25635" checksum="D09D039C019ACD27" modified="2021-09-29" version="1">MKLIPFVSIFVALAGCNLRTAQGAGRNGAFIGYHESEARREVTLAAQPKPGPFRVKISSSYGEFIIKLRPDLAPDTCTLVWELAQKGNCPACKFYRHEPVPMDWGRDGFWGPPYALLQGSLADLAREPPFENQGNSVKKGDICMIPNCKEFFIATADHPEWGHSHTIWGEVEDLSAEPNYPFEPFHSNTHDNITTRWLDNTYAFNLTAIEPVPLDTGSGSGTGARLLLNNAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B6N0</accession>
    <name>A0A836B6N0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Peptidase M3A/M3B catalytic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_005839</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="7">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
        <text evidence="7">Binds 1 zinc ion.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 7">Belongs to the peptidase M3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2449090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B6N0"/>
    <dbReference type="OrthoDB" id="550805at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004222">
        <property type="term" value="F:metalloendopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006518">
        <property type="term" value="P:peptide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1370.10">
        <property type="entry name" value="Neurolysin, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024077">
        <property type="entry name" value="Neurolysin/TOP_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045090">
        <property type="entry name" value="Pept_M3A_M3B"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001567">
        <property type="entry name" value="Pept_M3A_M3B_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804:SF79">
        <property type="entry name" value="MITOCHONDRIAL INTERMEDIATE PEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11804">
        <property type="entry name" value="PROTEASE M3 THIMET OLIGOPEPTIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01432">
        <property type="entry name" value="Peptidase_M3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55486">
        <property type="entry name" value="Metalloproteases ('zincins'), catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3 7" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 7" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="2 7" id="KW-0645">Protease</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 7" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Peptidase M3A/M3B catalytic" evidence="9">
        <location>
            <begin position="327"/>
            <end position="416"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="246"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="430"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="547"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="765"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="829"/>
            <end position="857"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="951"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="22"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="45"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="266"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="460"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="550"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="560"/>
            <end position="576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="583"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="609"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="829"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="967"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
        <location>
            <begin position="977"/>
            <end position="993"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU003435"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF01432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2449090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1156" mass="118687" checksum="BF7BF0F6C7D68E55" modified="2021-09-29" version="1">MSYAAASGPSPGPVSPASAASTSDGPLSRLQQPQPDDFTTGPPLGGRPPPPPGLEPGLYGLPGVTRPDDLVDTAARLVLVCGEVQAQVAREGRGERLALLVRRHHEAVAWLRAPAAHCAEHHTDARWRDAAARVERALQPPVPPQPTPRLVAEGVARAAALGGEDDEAAELRALEALEVALLAGWRQALADPDQAPPPVLLLHDSEVRGDPVLSQAASPATEADVAAARAGAGVQLQLLQAPVPAPVPVPVPSQERQGSRQGGGTAAAAGAEAASTSGQREPGGGSGDQDGPTVRLAPLTAATYKARMRGGRLWRVPLTGGLTSLLLAEHPSTAVRRAVYAATLGVQAGAALDLMDVLRRARDDTAHCLGQPSYAHLRAAGSVAGSPAAALQWLRELLDAVAPLAEAEVARLQRLAVRLAVQEREEAGLLGRGRPVRRGGGGGGSSGQQQQQHQGKGEGEHEEEEEEDPLDLVGSIDFLSGLEREPLPSAEEWGEQLAAYFELEGVLRGLSALLAPTLGLELRPSRWLSRHEAAWAPPHHLIKLELHDLLPPPPRPPASASPGAAGTLGTFGTGAAPEDASTPAVVPVPVPASNGSSSGGAGGRRSFRRSSPPSAGGKGSSSSSSSSSSSSSSDTTSSSSLVGVLYVCIDPECAMPFTSLVRHGFSSGGAAAPWLLPQLYAVAAPAPASSSSSSSSSPSSSSSAAASQAAASPSFTASSTSSTSSASSSSSTAGAAAATGACVPHVALHLPAHQLALCAVAPEEGAGERSPGAPPPPATAAAAAGASGSGAGGRFWLLEDPRLLRTLAHELGHSLHYLLSAAPAPAAEMHSAPQAGSSGSSSSALAGQPPLQPALQPAPLPEQCACYSSVDHLELASHITERWAADPAVLAALSCHVDNGARLRPRDCAPLAASLGRQRSWLELQQHALLAAADLALHLNGARLHLPSLRLRPDRGEAGGPQQEPAQEEKEEKKEEEKEEEKEEEEKEEEEGGEWIRLGPATPSRRLVAALWRAHSSLPGGRLVLSQQLMGLLPGLLHNAGAMYAYPMAQMVSAAVWERHFSDGLDSPRAARGGRLLRRWLLEYGEVGSAAAALEALLGPGSVRRVAEGGGWDGDREEDVGGRLGEAEGQAVIGSGSGVVPDLAADAFQDIDPLVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B812</accession>
    <name>A0A836B812_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="15">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_000327</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the SNF2/RAD54 helicase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000012">
        <property type="protein sequence ID" value="KAG2450230.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="5857104at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140658">
        <property type="term" value="F:ATP-dependent chromatin remodeler activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034728">
        <property type="term" value="P:nucleosome organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18660">
        <property type="entry name" value="CD1_tandem"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.40">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.60">
        <property type="entry name" value="Homeodomain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056302">
        <property type="entry name" value="CHD1-2/Hrp3_HTH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025260">
        <property type="entry name" value="CHD1-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016197">
        <property type="entry name" value="Chromo-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023780">
        <property type="entry name" value="Chromo_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023779">
        <property type="entry name" value="Chromodomain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002464">
        <property type="entry name" value="DNA/RNA_helicase_DEAH_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623:SF14">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45623">
        <property type="entry name" value="CHROMODOMAIN-HELICASE-DNA-BINDING PROTEIN 3-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00385">
        <property type="entry name" value="Chromo"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23588">
        <property type="entry name" value="HTH_CHD1_Hrp3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01176">
        <property type="entry name" value="DUF4208"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54160">
        <property type="entry name" value="Chromo domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00598">
        <property type="entry name" value="CHROMO_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00690">
        <property type="entry name" value="DEAH_ATP_HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0677">Repeat</keyword>
    <keyword evidence="9" id="KW-0804">Transcription</keyword>
    <keyword evidence="7" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="Chromo" evidence="12">
        <location>
            <begin position="298"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="12">
        <location>
            <begin position="468"/>
            <end position="531"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase ATP-binding" evidence="13">
        <location>
            <begin position="572"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="14">
        <location>
            <begin position="878"/>
            <end position="1034"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="414"/>
            <end position="469"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1144"/>
            <end position="1229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1484"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1718"/>
            <end position="2287"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="1"/>
            <end position="43"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="80"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="129"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="160"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="193"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="207"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="260"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="11">
        <location>
            <begin position="289"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="414"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="438"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1182"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1202"/>
            <end position="1213"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1519"/>
            <end position="1539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1540"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1582"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1605"/>
            <end position="1624"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1718"/>
            <end position="1741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1747"/>
            <end position="1761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="1799"/>
            <end position="1812"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1815"/>
            <end position="1826"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1827"/>
            <end position="1843"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1852"/>
            <end position="1888"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1903"/>
            <end position="1921"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="1930"/>
            <end position="1959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1985"/>
            <end position="2000"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2015"/>
            <end position="2163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="2164"/>
            <end position="2178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2179"/>
            <end position="2205"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="2214"/>
            <end position="2239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="2240"/>
            <end position="2260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="11">
        <location>
            <begin position="2267"/>
            <end position="2278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG2450230.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2287" mass="247776" checksum="E8F94F23FA46415C" modified="2021-09-29" version="1">MSSGDEEEPSVEPQDEDDRDEDYVANDGDDGGDDDDEEEDAASEDERPARRRGGGRTAAGAAASKRTRRTTRSAKSYKDDSEEEDFEVDDDEEEEADDDDDDEEEDDDDDAGDDDEEEDYAPRARRGRAAAPARPKRQAAQQAKARLTRRDTTEDDDEEIARAIDREINGLRARPRRAPAATIAFEERAVSPRGGGGGGGGGGGRRAGANSRASSAQPSGRAAASTGGGGGRRRAAPARTSQRSVAKVSYAESDDDSDEGGGGGGGGGGRGGRGGAGAGRVKEALSAFEDPDEDEVEDEVDKVLAHRDSANLPPAPPNDPWSAREFLVKWKRYSYIHCSWNSRGALERLRGYKRVLNYIKKVDDVEAGRRFFSREEQEMQDVEREMEAQLNQQHMMVERVMAEKEATIFAAEQPAASAAAGDAGAQQQPGQQQAAADGEGGGGEAAERAGGVGAGLGAGGRELVGPPGEQRRELEEAEAEVVAVTKYLVKWEGLPYAECTWETAEDIVRAGGSAQIDSYLQREQRLLEPGRGVEAARKQFRIKGTRALERQPSFLMGGTLRDYQMESLNWMIYSWSENRNIILADEMGLGKTVQCVSFIGTLSEQLQIRGPFLVVVPLSTVPNWIREFRRWVPFVNAVVYVGDSRSREVLRAYECDPSAHHKAARPYKFEVLLTTYELILKDAPILSRIKWAYLLVDEAHRLKNAESALYQELMEWHFANKLLITGTPLQNSLKELWALLHFLEPGRFPTAEAFEAEYSLETADSVSGLHGVLRPHLLRRVIKDVEKSLPPKNERILRVDMTPLQKQYYKWILTRNFKELNKSSRGGGHVSLLNIIGELKKCCNHPFLFESAEDNYRGSEEDKSAVDRLIVPSGKMVLLDKLLRRLKATGHRVLIFSQMVRVLDIISDYMRLRGFPHQRLDGSTPAAARHAAMEHFNRPDSPDFAFLLSTRAGGLGINLATADTVIIFDSDWNPQNDLQAMSRAHRIGQTETVNIYRFVTSGSVEEDILERAKRKMVLDHLVIQRMDTSGRTILDPSAGKAAKQMFGKDELAAILRFGAEDLFKQPAQPEDDNASAAAAERAARTALYEDDLDAILERAEVVDTRQLAAADENAAAAAELLSSFNVATFKNEFGEDDAAFWNKLIPPSERPKDEEEELLPRAARRAQDASAGADSDDDGDGAAAGNGAAAGGRKGGRGGRGRAAAGGAARARGAGAGAGGGEPGPPVDGAALRVDEWIVEVDEEGIPLIKEDGSEPEARSLSRRDAAAFVRAVRRYGRPERLADVSAEVGRSLEEAGPGQRLSLWYGLMDGCKLAVQRTTEEQSEDAKDAILDFFGVSVKAAELLTACSHLRLLAKKVAAARDPAATHFRLDATSQLSVPKWGKPINWTARDDALLLLGVHLHGLGHWDKVAADEALRPFLADKLAGAVGGGGGAGGGGGGGGAGAGGAGGVGGGGKEDGGAGLPKASHLETRALGLLRKMHATHKAATAVAPARRGRNNNQGAAKASKPHLDKEHRPGAAAAAAAAAADAAAAGPSGAAREREREREREPSVAARDGGHHANGTGPAGGKRKAGAAAAAAHADDGAGPSEKRARVDSKGEDASPSHAGGSNAAAAAGNSSGPVGREELKSLLEPALPDIKRMRKLQDGSVTDKALVVRSTKQLLTAIGGHIQRVAASRGPKVGKKLWDLAAKTIGNGKTGEELHMLHTRLAQQAAPPAAAGGAAAGAKGAKGAAGAKGKQVQQHSPEQEQDKARQTEKGRAQAQHAQHRQQHQQEGSADPKPVQAAAPGSRATTVHSPRVERERSRERDRGGNQQSPQPKAASPPATAPSPHPHPHLSPLPPRGHAATPPVAAPHPHPQVPGPHPPPGNPPGHSPPPPPGPRPPSEPYPHSHHAHNHGTGPGIPPPQPPRVPPPQPPSAPYPYSAAPPAAVPPPHPPPPPPLPPSLPPPEPPLPPPHSQPAAGGEAARAHSPARGSNQRPTPPVVTGAAASPPAAGGAEAAERGRTGEGSAPPHDPRDRDRDRERERDGEGRREWRDRHSSRSRSRDRDRDRDRDYRSRDYDRDRDRGARDRRERDRDRDPRDRDRDRDYRSRDYDRDRDRDRDRDRDRDRDRERERERDRGDRDRSRERARSRSYHEDRDRDRGRDRDREYERRGGRSRSRDARRRSRSTSRSRSRDRRDWERDRDRERAGDRDRDRDRDRQRRGASAAARSRSRSRSRGRGRSGSRDARRRSHSTSRSRERRDAERPREREREREEGAAAAAPAAPPPPPPPPPAETAEQAAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B925</accession>
    <name>A0A836B925_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">DUF676 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_004001</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451401.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B925"/>
    <dbReference type="OrthoDB" id="273452at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007751">
        <property type="entry name" value="DUF676_lipase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044294">
        <property type="entry name" value="Lipase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482">
        <property type="entry name" value="LIPASE ROG1-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12482:SF11">
        <property type="entry name" value="LIPASE YOR059C ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05057">
        <property type="entry name" value="DUF676"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="DUF676" evidence="2">
        <location>
            <begin position="1"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="216"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="258"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF05057"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2451401.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="386" mass="39540" checksum="56247A0C8A629785" modified="2021-09-29" version="1">MGGMIARYAAGLLYRPADGTLAGLAPRHFVTLASPHLGLTVDVGPAQVPFVAWAAHLPLLGGPLQRGLQAIGHTVAARVFRGTGRHFLALDGGPGELPLLMCMALDEPDKGRFFYSALRAFRTRACYGNVGRDHWVSWQNATLRDTAQLPHLEPELVRRGRGVVHEDPPQAAWSSGAGLSGGGGGRTGADAAAAAAVAAAGYGVTEGACEAKAEAEGAGRDVQRKQTAAAETVAATTAGSEQPRTESGGQGGGGAGVGEAAGAAACAAQVAMPKALAGDAAAAEAQAQAQAQAQAAADAADVELEEQLTAAPESPAQVVSFALERLQQLPWRRVDVSFAGAHMGTAHNNIQATRWTNTVGAGVLRHLRQHLEAMELYVAAESPGRV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B9Q1</accession>
    <name>A0A836B9Q1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ATP adenylyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_003745</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451972.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B9Q1"/>
    <dbReference type="OrthoDB" id="10267950at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003877">
        <property type="term" value="F:ATP:ADP adenylyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008796">
        <property type="term" value="F:bis(5'-nucleosyl)-tetraphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004780">
        <property type="term" value="F:sulfate adenylyltransferase (ADP) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009164">
        <property type="term" value="P:nucleoside catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009165">
        <property type="term" value="P:nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043171">
        <property type="entry name" value="Ap4A_phos1/2-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045759">
        <property type="entry name" value="Ap4A_phos1/2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019200">
        <property type="entry name" value="ATP_adenylylTrfase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053364">
        <property type="entry name" value="Fork-head_TF_regulator"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42746">
        <property type="entry name" value="DIADENOSINE 5',5'''-P1,P4-TETRAPHOSPHATE PHOSPHORYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42746:SF2">
        <property type="entry name" value="DIADENOSINE 5',5'''-P1,P4-TETRAPHOSPHATE PHOSPHORYLASE 2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19327">
        <property type="entry name" value="Ap4A_phos_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09830">
        <property type="entry name" value="ATP_transf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ap4A phosphorylase 1/2 N-terminal" evidence="3">
        <location>
            <begin position="66"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="ATP adenylyltransferase C-terminal" evidence="2">
        <location>
            <begin position="286"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="131"/>
            <end position="142"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF09830"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF19327"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2451972.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="413" mass="42783" checksum="A2CDF037DDE9ADA2" modified="2021-09-29" version="1">MLQCCTRRTAQNPRFQVAASSAWTSGAALRPAPLQRRTTATAPMAAAAPPKAAAAAATAAEPGRARDPAALWDEIVSVYNRGQALGVSSIAETKPELCRDDSLGVDFVLRVATALRAKPQLPPQAPEQDKAAAAAAQPAARPWRNPFMPPEPELTVCKVGAAGTHTAVLNKFNVVEHHVVVITNKFRSQAEPLSGEDLAAALEVLEAMPQGGVAFYNCGPESGRSQPHKHLQVVPLPFMEGQPPQAPVHVLVEAAMAAAAAAGTAGGGGGSSTSTAAPLQPLQLRQLPYQCFATPLPDSPTPEQLGAACDALLQLAFPGYSYSPTPAMASLPAGASPTDTVTAAAVAAGSVSYNVLVTRQWLMLVPRRAECCGPLALNSLAFAGTILVRSEEVLGFVREKGPAAILAEIGVPW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B9Q6</accession>
    <name>A0A836B9Q6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein phosphatase methylesterase-1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_004178</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451580.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B9Q6"/>
    <dbReference type="OrthoDB" id="284184at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2451580.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="66" mass="7503" checksum="16FE7D7C9BAC0152" modified="2021-09-29" version="1">MKDLCVIIPGAGHRSYEDKPEVFHKVLLTFLKKCRRSADGILHEVMSEHGIELVRTLRNAEKDGTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B9S0</accession>
    <name>A0A836B9S0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_003058</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B9S0"/>
    <dbReference type="OrthoDB" id="336747at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050205">
        <property type="entry name" value="CDPK_Ser/Thr_kinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24349">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="7">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="57"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="188"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="237"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="57"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="81"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="188"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="6">
        <location>
            <begin position="213"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="259"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="273"/>
            <end position="283"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2452017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="283" mass="27447" checksum="49DB8FCDDC4537C4" modified="2021-09-29" version="1">MLAVCSAPIQFLSPEWRGVSRDARDLVTRMLDRNPATRLTAEQALEHPWFARWMAQAAHGSHGATHTADKSPARQHQQRHAGASPSRPAASPSAAAPAAGAPKRCVAGSPNAAGCQGAGGSSGGGGGGSNIVPVPAAVAVPVALPADVLSCSSMDGGCPADVFHHAASNGNDSGSGAAPSAAAAAGQAACLPAARPQPQHPQASSPSSARQAPLPPPSRPVPEPHVQQVLGQMLGPLEAAGGGVSSGSAGSEDEHNHQSAAAAAAAAAAAGNGANGGGSSNAV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BBC4</accession>
    <name>A0A836BBC4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynamin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_001663</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453441.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BBC4"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001030">
        <property type="entry name" value="Dynamin-related protein 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF169">
        <property type="entry name" value="DYNAMIN-LIKE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="3">
        <location>
            <begin position="103"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="637"/>
            <end position="664"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="697"/>
            <end position="716"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="639"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="697"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2453441.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="839" mass="91410" checksum="BE69708387110D56" modified="2021-09-29" version="1">MSTSSRHHENPVYDRERDAAPGGDQHISSSHARAHHAGSGSGMHGQHKPGSIQVQAGGMVRRSQAADSSLRESTQELFETSEAQIRYRAYSRLQAAAVAMGESLAIPEIVAIGGQSDGKSSLLEAFLGFRFNVREVEMGTRRPLIVQMVHDPTAQEPRCRLQEEDSDEYGPPIVPETAVADAIQRRTEEHLRKMGGIAVSSKPIVMRAEYAYCPNLTIIDTPGFILKAKTGELDNTPDEIMSMVKAQASPPHRMILFLQQSSVEWASSLWLRVVQEVDPYFQRTVIVASKFDNRLKEFAERWEVDKYLSATGYLPPNVRPFFVALPKDRVIQSSAEWRRSMTEVDAAIYKHMRDGIKGGFDEERFASRIGFSNLKKFLEEELSRRYREAAPATLALLQERCDAVSAELMAAEIRLKSAEDVGALRRAAMKYADTVARQVVSLLQGSAEPDPVQHGLTTDEERAASRAPQWPGVSGASVQPLHHDSKLFGGAAFERCLEEFHMAVAHTRFPTSMSNDRLRNIMYAYKGKHHNGGAAKAAEDIARQAAKEALGPLLDAACVRLAFILRRLFDIAADRAAATMGSKDNLHPYISFHAALRSAHQSFISRLEEQARAMLRTHLEAATSQFAMNMYAHVPDPGDPLDVDEEDGDADGAGEDAEGAMPTPGPARVQMTVPETPSSAATAQVLNERLKAVQLGGGAGAPGGPGRFEDNTPSRRATKSRRVALQNAGGMGGVLAGGGASSSDDVVSASEALFRKIRLAVATQYAPATLKSTFLDPMTDRLGLEVSLDLFARSDSDFGAMFSAAGAVAALASKRDMLARRVEGLIKCKNEFQELAKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BBE8</accession>
    <name>A0A836BBE8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Rhodopsin</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_002190</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452844.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BBE8"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452844.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="159" mass="16963" checksum="B0EB4058ED328BE0" modified="2021-09-29" version="1">MSHPPPGYPGGYPPPGYPPQPGYPPPQPGYAPGGYPPQPGYPPQPGYPPPGYPPQHGYPPPQPGYAPAPHGYPPPAGYPPPGYPPPAGYPPHGVPHTVVVPVAVHGAPHGYAPHGGHYKKHKGYKYKGHKGHYGHHYGKHKGGHYGYHGKYKGHGKHKW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCE5</accession>
    <name>A0A836BCE5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">histidine kinase</fullName>
            <ecNumber evidence="4">2.7.13.3</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_001381</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>ATP + protein L-histidine = ADP + protein N-phospho-L-histidine.</text>
            <dbReference type="EC" id="2.7.13.3"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the archaeal/bacterial/fungal opsin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.13.3" evidence="4"/>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="60033at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000155">
        <property type="term" value="F:phosphorelay sensor kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd16922">
        <property type="entry name" value="HATPase_EvgS-ArcB-TorS-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00082">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000010">
        <property type="entry name" value="Sensor histidine kinase RcsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.130">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2300">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1070.10">
        <property type="entry name" value="Rhodopsin 7-helix transmembrane proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001425">
        <property type="entry name" value="Arc/bac/fun_rhodopsins"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011006">
        <property type="entry name" value="CheY-like_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003661">
        <property type="entry name" value="HisK_dim/P_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036097">
        <property type="entry name" value="HisK_dim/P_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004358">
        <property type="entry name" value="Sig_transdc_His_kin-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001789">
        <property type="entry name" value="Sig_transdc_resp-reg_receiver"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047:SF71">
        <property type="entry name" value="HISTIDINE KINASE CONTAINING CHEY-HOMOLOGOUS RECEIVER DOMAIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43047">
        <property type="entry name" value="TWO-COMPONENT HISTIDINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01036">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00512">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00072">
        <property type="entry name" value="Response_reg"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00344">
        <property type="entry name" value="BCTRLSENSOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM01021">
        <property type="entry name" value="Bac_rhodopsin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00388">
        <property type="entry name" value="HisKA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00448">
        <property type="entry name" value="REC"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52172">
        <property type="entry name" value="CheY-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81321">
        <property type="entry name" value="Family A G protein-coupled receptor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47384">
        <property type="entry name" value="Homodimeric domain of signal transducing histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50110">
        <property type="entry name" value="RESPONSE_REGULATORY"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 11" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0808">Transferase</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Histidine kinase" evidence="13">
        <location>
            <begin position="276"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="778"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="domain" description="Response regulatory" evidence="14">
        <location>
            <begin position="998"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="530"/>
            <end position="581"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="593"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="677"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="729"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="940"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1478"/>
            <end position="1497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1627"/>
            <end position="1678"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1804"/>
            <end position="1826"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1853"/>
            <end position="1878"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1968"/>
            <end position="2017"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="540"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="557"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="12">
        <location>
            <begin position="593"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="604"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="685"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="731"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="945"/>
            <end position="955"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="12">
        <location>
            <begin position="1633"/>
            <end position="1645"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1661"/>
            <end position="1670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1854"/>
            <end position="1868"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="1968"/>
            <end position="1995"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="11">
        <location>
            <position position="829"/>
        </location>
    </feature>
    <feature type="modified residue" description="4-aspartylphosphate" evidence="11">
        <location>
            <position position="1052"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00000085"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00008130"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012438"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG2454356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2017" mass="199962" checksum="577F58D911C3A4D8" modified="2021-09-29" version="1">MLGRAFFHNPAGLAELRKEVPNSVYDRSSSIFLTALAIDILNIVFERQTIKLDCVLLPAFIKGMASTTNVLVRFFTPVIALTNMGRPVVVQRYICWMHTTPSILMLLKMISTTITPRETMIAIFFDEVMVVTGVLALVTTGWQRVLWSFLTHAAMLPVVPYMHKAFTEAMEQIRTRPLQLTMLCIYVLNLVLWCTFAVTWDLALLGWISVTVEEVLYVGCDFSAKVLFSSTLMLSSFKEIEARRENAMRVIEGSSKAKLIAELQALLEQKERFMSSVSHELRTPLNGIIGISEGMLSGCCGVLPEGVRRQIYIIRTSGARLLALINDVMDAAALRQNKLVLKQEQVVLRHVVDDVLDLTRSLVDGEVALVNLVPPRMMVLGDTGRIVQILNNLLGNAAKFTRRGQIRVTARQVEGGRKVAVTVSDTGIGIPRNKLATIFLPFEQVDMSISRKYGGFGLGLNIVQELVKAHGGTINVSSIEGKGSAFTFTMPLVRALGRESLEEGRNAAQRAAAAGSNVAAKLLAGAGMSTTDTSSQLGGSTSGSGCGPGGGGGGTISGAVSTATPRAGARTPGGAAATTVSDYPADTDTVYTHRSDLSESSRARGGGGLGGGLGGDSQSGADATTAELEQYGELKYNAAELSALASSRPYAQSAARDSLPSLGADGVAMPSGALSPSTAFDSSAGGVGSAAGLGRGSSSQLPVLPSGAGAASAAVAAAARARSRAVERSGAGAGAGAAGGKAGGGGGGADGAVAAELPGGKIVPGPKPFHYTMYKRFQLLSVDDDPVNQSVVKSLVQGTGYEVVSARSGAEALRWVAGAPALPDLVLLDCMMPEMDGYEVLQRLRAMTPHVHLPIIMVSAQTEEDHVVCGLDLGADDYVTKPFKRAELLARIRSQLAYGEWEQDEGVFDTISTMDGGELVNAAAAAANVAAGRGVMGGPAPLPPGGSGGSGGAAGGSDDSEAGAVSAALGSLQTGPGGVAGAAGGDGLGGASAADQRLIVCIDDDDVNQVVLQGMLASQHYRYVRASTGAQGLAFVCGPSNGGIPPDLVLLDCSLPDMTGFDVCRVIRQMYNKQQVPIIMLSARHNESAVVEGLKCGANTYVTKPFRRNELLARIRLHLRSRDGPLQRGASSNDMGQMDEAAAAAGAAAAAAAAANAAGAAAAAAAAGMVGGADIGGGPGFGAQQPSLSFGLGGLGGGSYGQVASPTALPGAVAAQAPLGALTSSSAAAAAVFPVSAVLVVSVADYAGLCGMLLPGEMAELSGRMLAAFERAVRAAGALPIEAGSGVMSATVLPPPPSAAAPPPQTAAAADAAAGLRLAALHRVGRALLDAASTIPVPGTTTCLQLQQALALGTLTVSGGGAPTATGGGAAAPSFFGPVLAELLDLARRAPPMTIVTPDVEAAALRACGATADIRGPLFLEAGDVAAGAGGNGGAAGGGGGPLVSRRLWLVEAHPLAHQYLPPQLLFASGAARGTLFQLPPGSAAPPGGAEAAPAQAGALGQGAALAEHQLQQQPATRSGSAVLLGGAGAAVGAVGGMVPVSVHQAPGIGAVPADGAGGRGFGSSSVASYGAAGGGGVPGLMAASSGLGGPVMGLGLYANGAGVSRGVSRAFSHAFGLDSDNHGRANSTAAGSVGGGSVAGGGAHTGHTAATSGNGGTSGNGASQSSGPTVGRGGGGGSDVAAAAAMSAVLPSGLDSSSVAGITFSLQAAAAAVAAASTSGGVVGGGGGGSAPQHLPSVTGVSGVLLSPAGGGSGLHDSAGGGSLYFYGSGGAGAAPAGGRSSLQPFGAMLGGGVGGGPGMGYAPAAMHPQLQQPPPQSQQVDLVSAAAAEPQIRALRHELAAMRQQLEALQGAASSSSASNTVAPATGGAGGSAGQQPRLLAPQQQLSQAQLSPQLTQQQLSSQLTQQQLLQQQMSIHQGFVDAALAAAAAAAAAAAAAPPGGGASASGMAPPGTAAGLLPAAAASSVGSAAPPAPTESEAGAASNAGSAAPAEKPSKKGGKISRLFKMGSSKNGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCE6</accession>
    <name>A0A836BCE6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_001425</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 4">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454402.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BCE6"/>
    <dbReference type="OrthoDB" id="1933717at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963">
        <property type="entry name" value="CARBONYL REDUCTASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43963:SF6">
        <property type="entry name" value="CHAIN DEHYDROGENASE FAMILY PROTEIN, PUTATIVE (AFU_ORTHOLOGUE AFUA_3G15350)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00081">
        <property type="entry name" value="GDHRDH"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00080">
        <property type="entry name" value="SDRFAMILY"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0521">NADP</keyword>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="RuleBase" id="RU000363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2454402.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="277" mass="29434" checksum="61F97AD14144EBBF" modified="2021-09-29" version="1">MALATDKWWDANTVAVVTGSNKGIGFEAARMLAEQGLTVVVTSRDVEAGKTAVAKIKEAAPGARVLLHQLDIANAASVDAFVAWLKQETGGLTVLVNNAGFAYKGNIFGADEAQTTMAINFAGTRNLTEKLVPLLQGPCPRIVNVSSRAGLRSIIKSKELLGRLTAATSPDQLAAMADEFIAGIRDGTYGKQGWPGSMYGTSKLLVSLWTAQLAAQLKERHVMVNAMCPGWCRTDMSSQSGNKSAAEGADTAVWLALRSPQDFVTGGFWGERSNISW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCG8</accession>
    <name>A0A836BCG8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Kazal-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_001436</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BCG8"/>
    <dbReference type="OrthoDB" id="544930at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00104">
        <property type="entry name" value="KAZAL_FS"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.60.30">
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002350">
        <property type="entry name" value="Kazal_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036058">
        <property type="entry name" value="Kazal_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053265">
        <property type="entry name" value="Serpin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21131:SF0">
        <property type="entry name" value="GEO10195P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21131">
        <property type="entry name" value="SERINE-TYPE ENDOPEPTIDASE INHIBITOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00050">
        <property type="entry name" value="Kazal_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07648">
        <property type="entry name" value="Kazal_2"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00280">
        <property type="entry name" value="KAZAL"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100895">
        <property type="entry name" value="Kazal-type serine protease inhibitors"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00282">
        <property type="entry name" value="KAZAL_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51465">
        <property type="entry name" value="KAZAL_2"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="352"/>
            <end position="376"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="3">
        <location>
            <begin position="84"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="3">
        <location>
            <begin position="165"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="domain" description="Kazal-like" evidence="3">
        <location>
            <begin position="223"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="324"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="436"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="14"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="395"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="478"/>
            <end position="503"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51465"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2454416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="522" mass="52472" checksum="31F20541CA3A2EB2" modified="2021-09-29" version="1">MQAKTSSSTGSKSKSPPPATVKFVGGASPPLVAAAGEPSPADACLCPDIYAPVCASGPAGDGTIDNACQAQCAGLHVVYPGPCVQAADGCGSIASRTTYAPVCGGDGNTYANRLQAECGGVSVASEGRCGQLKCVCPLDDDVQVCGADGTTYDNECRSRCAGVAVKHIGPCAKPDGCANVTCAAAFAPVCGVDGVTYDNACKLGCAGVQLLHKGPCGVTLRMTRLPSACACPSTWDPVCGDDYLTYDNAQCATKCAGVSLLYSGVCAPAASCIGTFCVPEDILSCGANNVTYDSVCAATCVGNVAVARSGACEAPAPPLRPLIEDLPTGPDIELPPTSPSQSRSSGGLSSGALVGIIVGCVGFVSALALVLLVVLLRWRRARLDRDPAAAAAGADGDRDAHDHANSQLQGQKYQQQDALKLKLAGLSSMETWALGDSVTHSEDTPRVASSEDSPHPYPRMTPRAAGLPRIVSNRVRDSSSSGTPGAAAAQPGGADFAAGSSAAVATAMQQGFTDLLATAPPV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SBR8</accession>
    <name>A0A835SBR8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000130">
        <property type="protein sequence ID" value="KAG2424059.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="298589at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="90"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="369"/>
            <end position="445"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="588"/>
            <end position="659"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="671"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="809"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="950"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1098"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="97"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="172"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="384"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="593"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="626"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="707"/>
            <end position="722"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="817"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="839"/>
            <end position="850"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="869"/>
            <end position="897"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="915"/>
            <end position="925"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1128"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1176"/>
            <end position="1199"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1232"/>
            <end position="1263"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2424059.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1341" mass="136119" checksum="67F848A48A52D4AB" modified="2021-09-29" version="1">MADEEIPVNELLVDVEDGIVVGLYHYLWLKDGKGRPCPEVNIPHTIIYANGRPVVWYFTSGKDRCIKRKHKSTISNPAINAAFAPSSKTITEGYGGETSQHNNAGSGWGGLNSTAPAGTASQKPLGNGRDRPALSQTAGGTGAGNGRPMDGSSTGTALGPWPHHGVVGRFQGSMTLPHTASSASGHNARPGSPSRRKKGGITVELVDEAREWFSRETLREVVPPGAVVVHGVAALHEGVLQKFVQPRGQHYFLLRATWSPNACVVERRTAKSKINDPRVPLSERLAGFDSPVWMSEHTLITGTVLQGTVGRMCDNIAAHLADVSKGEVRVLRMVLYFAVDEANRIWLTHASTLRTQRPREEAVLAGLARGNSQRQHGSGGGAGPHHHPHHAIQHQHSRHQRALDVGGGAGSEPEPGAGLDLPAPSPAFASTRPAAGEGGDEDGAGSSGRFLCVLTGEMYPGSSRCDVTYKQLLQHWFSLASQLPNEGDRLRAMDTIPLAIRRANPSLTREWYLRVRSQPNFLYRTAPVCAEAAGQLTGVALEELQRTMAGRPGTTSAAVAAMSGVGLTQAASVSGAQPLGRLVAARTGQGSVSQGGGFGAGLAGTGRPRPVTALAAMLPPPPPPAQSQQARPPSRQHQSTSGGGGKAPAMRSKSASAALAARMHAGGGGGGFVDPLGLSQSSRPRAQTAAPSRYGPNSSAAMVAHYGSSSSSTGPGRSSSQGQGQGRGLPSMLVPRDKGAGAGRPGSALLQAYGPTPEQAAEAAAAAAALPYEVLDQQASARQRGEGLVGGLPSAILASEHAANGITGAGSAAAQAGPGGAGVSQGAAGTGGEGSAAQVWTTGSGTSQFRSAPPPALGNSRRSAMMRMSTCSDATEVGSNHSLSEPTSPNGTPLQASGGSGQAYHPHHLHHGHVSGSGGSPGGGSSSAPATRMSPPRSTGLLTLQTIHEEGATAPPPSRAGDPRAGLGDADVYPPPTRGSGAHSVPRMRPPARGGSDRPPAPGASGPSRRQMPYPYSGSTAVAHRSLSESGELQAYGGGGGSLNSTMASSVSIASRRSTSTQALLSNDDVRTLRELNEAYSAAERLTQQLLAQAHEILSDEGSRPPSTGTSPHRPPHGAGGAGGAQRRPSNTMLSPPTSLPNSRPGSRHGRNGDGSGSAPSAYTSLMPPPSSGQAVRPGSSSGPQPPSRQQSVGAASTGSGAGGGGAREAAGSVGSTSGGRPPGLPPAGQRLGSTNLGRSPLSQVSRTSSGRRPGSVGSNDGSTLEADSGSHAGAQASGLARAPSTSGHAVTEAMCLAGGLAQDGGVELEEDVRDSGPMAAPATDLFTSAEAELLTEALQD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SDW9</accession>
    <name>A0A835SDW9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ARID domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_015380</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000181">
        <property type="protein sequence ID" value="KAG2422942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SDW9"/>
    <dbReference type="OrthoDB" id="338531at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd16100">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd15615">
        <property type="entry name" value="PHD_ARID4_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.150.60">
        <property type="entry name" value="ARID DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042293">
        <property type="entry name" value="ARID4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001606">
        <property type="entry name" value="ARID_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036431">
        <property type="entry name" value="ARID_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019786">
        <property type="entry name" value="Zinc_finger_PHD-type_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46694">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46694:SF1">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01388">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01014">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00501">
        <property type="entry name" value="BRIGHT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46774">
        <property type="entry name" value="ARID-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51011">
        <property type="entry name" value="ARID"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01359">
        <property type="entry name" value="ZF_PHD_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="ARID" evidence="6">
        <location>
            <begin position="22"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="domain" description="PHD-type" evidence="5">
        <location>
            <begin position="127"/>
            <end position="187"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2422942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="200" mass="22655" checksum="CD44AD5C7D9598B1" modified="2021-09-29" version="1">MEWDCNGAAHPGYTCRRPPLSACSEAQFYDDLCEFLALLRGKPVERSKFPEAVLNGVSLDLFALYREVVSRGGFRVGNGINWKGQVFPRMRNWTESNKQTGVGNALKRHYQNYLWEYEVAHPEDVTLDRCVLCNARDREGGAGDWLCCDCCENWVHLSCDKRPGLGAYKDYTQGNGRVYVCPSCSREQDAGEALKRQRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SEY3</accession>
    <name>A0A835SEY3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">N-acetyltransferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_014955</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000113">
        <property type="protein sequence ID" value="KAG2425739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SEY3"/>
    <dbReference type="OrthoDB" id="549049at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008080">
        <property type="term" value="F:N-acetyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000182">
        <property type="entry name" value="GNAT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050769">
        <property type="entry name" value="NAT_camello-type"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947">
        <property type="entry name" value="GNAT FAMILY N-ACETYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13947:SF37">
        <property type="entry name" value="LD18367P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13508">
        <property type="entry name" value="Acetyltransf_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51186">
        <property type="entry name" value="GNAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032640974" description="N-acetyltransferase domain-containing protein" evidence="4">
        <location>
            <begin position="27"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="90"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="domain" description="N-acetyltransferase" evidence="5">
        <location>
            <begin position="256"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="161"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="233"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="411"/>
            <end position="440"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="161"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="293"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="411"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2425739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="440" mass="44696" checksum="0451220249D3B3EF" modified="2021-09-29" version="1">MAWRRFARYACALAAASLLLTAGAYAALRDPATLQAAAAATAAATAASAATASSSASSTLLGAALTSYLQPLLTGLQLVATDAAGVLPRWALAAAALLGLLLPAVMTAMPRQLQVRLMRPLMMRGVWSYCPDMKDMYGHWSRPEEGREYYVAVGLRELSPAGPADSSSSSSSSSSASGDQGEPAAAVGKRWAEEGEVVLGGVAIKAGAGLRPLPPPAADCAEQTAVGRMLPAAASAAGVSGDDKEAEQEEEQQGRLRQRKPPPAPAAAVATAAAASKSPHSSSATATAKASKDGGGGAHGTGAGADAELPTGFCAGESGYHDNPGPCDILVFRMVVDPTVRRRGVGRRLMVHVMGRAAAVGGARVLLATGNPEAVRFYEACGFSKDGLKQPHGNLLGRAVAAPAHVVPGTREEAAKVKMGGDEEGVGQQQQQQQTVSKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SLE9</accession>
    <name>A0A835SLE9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_014096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000087">
        <property type="protein sequence ID" value="KAG2429159.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SLE9"/>
    <dbReference type="OrthoDB" id="548621at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319:SF35">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN PMPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="296"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="339"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="408"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="473"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="522"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="546"/>
            <end position="569"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="92"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="201"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="665"/>
            <end position="1038"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="167"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="210"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="666"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="684"/>
            <end position="723"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="733"/>
            <end position="747"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="756"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="808"/>
            <end position="822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="835"/>
            <end position="847"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="848"/>
            <end position="862"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="941"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="960"/>
            <end position="970"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="971"/>
            <end position="984"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1000"/>
            <end position="1013"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2429159.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1038" mass="104375" checksum="9537316499C1932E" modified="2021-09-29" version="1">MRDSLRCWWASAASIEPASQIHDYIRAQLVRSGEEKAARARAKAESRAASMTAAQAAAAMQRSILGGGGGGGGSPSLSAAAAAAAAQKLARGGSRDEYSDGDGESVGKGGGGGPPARKEDSVLPITAAAAAAAAAATAERGPVAEGIAQQEATKQQEEEEDGTKNIPSHPSSQQHQQQLHPQAAHKGAVVGFAPDTAAAGAVAKAAPPSGAHGGEVPAEESVRDEELMEGTHSIVIKILVSYLQVAAIVKDVAVVWPSPVAWLLNLGNQVSSGVTTMVSLDCSLPENTIPKSVQKVLITCFVPFILLALSVPTWFAIYGWKAQRKQRQGLVPPPAQPYLRTRLIVTAITIVFFTYPDVTDALLGIFACPLLDDAAGPSGGAPYADQLQAAGRWWSSDYNLKCYTGPHLLLLLVFGLPGVLAFSCGVPAFSAWFLRRNTALLRDRKFYRAYGFLYTDYEDRCYYWESVVMLRKLCMVIVVVFLGVISVQVQLLVSLGIILTALALQMAYDPYRCPRMDLLERLSLIGTTIIIYIALFFLLDISNTASIALSLTLVTINALIMAWFILILVREYAHGIMHGLDADGDGVLSAGDMGQSLDELAAKQPWLAHRLLALDGWLRARRRLAALISQAYPYGEPGDPWVVRHTAAEDYDDTAAAAAAAAAAAAGGGGGGGGGGADDDQRQQRQGSSSRDASASAPPLPGGAAWSKIQYQKQQPQEQQQQQGMAVREAAALGGGGGGGGLSGGGIPAAAPPPAATTTAASRGASLDRGPIRVSSSTSRSRVAPEPLPPAAATATAAAGGAGARPLSGSTGAAVSSGGRRSSAWEHSDLMAAGGSAGAGGGGGGGAADAAGSSSNSNNTAGVLVGPGPSPPASRVGSARVMPTPAVAAAATAAAGGGGSSSGAGAASSSRLGPGRTGSITGASAGGGDILSPPLPPPAPRASSGSVRDGSVSGGGGAAAVGVAGAVGTSSAGGGGGGGGGGGSRPMSRQRVADGSSSVAPAFGSGGSYSAAALPGLDPDSDLPAEPLGPAMSPRQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SS31</accession>
    <name>A0A835SS31_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1 11">Tyrosine--tRNA ligase</fullName>
            <ecNumber evidence="1 11">6.1.1.1</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="8 11">Tyrosyl-tRNA synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_013029</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9 11">
            <text>tRNA(Tyr) + L-tyrosine + ATP = L-tyrosyl-tRNA(Tyr) + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10220"/>
            <dbReference type="Rhea" id="RHEA-COMP:9706"/>
            <dbReference type="Rhea" id="RHEA-COMP:9707"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:58315"/>
            <dbReference type="ChEBI" id="CHEBI:78442"/>
            <dbReference type="ChEBI" id="CHEBI:78536"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.1.1.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="11">Belongs to the class-I aminoacyl-tRNA synthetase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.1.1.1" evidence="1 11"/>
    <dbReference type="EMBL" id="JAEHOD010000068">
        <property type="protein sequence ID" value="KAG2432307.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SS31"/>
    <dbReference type="OrthoDB" id="337870at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009570">
        <property type="term" value="C:chloroplast stroma"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004831">
        <property type="term" value="F:tyrosine-tRNA ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009791">
        <property type="term" value="P:post-embryonic development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048608">
        <property type="term" value="P:reproductive structure development"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006437">
        <property type="term" value="P:tyrosyl-tRNA aminoacylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00165">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd00805">
        <property type="entry name" value="TyrRS_core"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.240.10:FF:000001">
        <property type="entry name" value="Tyrosine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.290.10:FF:000014">
        <property type="entry name" value="Tyrosine--tRNA ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.290.10">
        <property type="entry name" value="RNA-binding S4 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.240.10">
        <property type="entry name" value="Tyrosyl-Transfer RNA Synthetase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_02006">
        <property type="entry name" value="Tyr_tRNA_synth_type1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001412">
        <property type="entry name" value="aa-tRNA-synth_I_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002305">
        <property type="entry name" value="aa-tRNA-synth_Ic"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002942">
        <property type="entry name" value="S4_RNA-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036986">
        <property type="entry name" value="S4_RNA-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054608">
        <property type="entry name" value="SYY-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002307">
        <property type="entry name" value="Tyr-tRNA-ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024088">
        <property type="entry name" value="Tyr-tRNA-ligase_bac-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024107">
        <property type="entry name" value="Tyr-tRNA-ligase_bac_1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00234">
        <property type="entry name" value="tyrS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766:SF0">
        <property type="entry name" value="TYROSINE--TRNA LIGASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11766">
        <property type="entry name" value="TYROSYL-TRNA SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22421">
        <property type="entry name" value="SYY_C-terminal"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00579">
        <property type="entry name" value="tRNA-synt_1b"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01040">
        <property type="entry name" value="TRNASYNTHTYR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00363">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55174">
        <property type="entry name" value="Alpha-L RNA-binding motif"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52374">
        <property type="entry name" value="Nucleotidylyl transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00178">
        <property type="entry name" value="AA_TRNA_LIGASE_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50889">
        <property type="entry name" value="S4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 11" id="KW-0030">Aminoacyl-tRNA synthetase</keyword>
    <keyword evidence="4 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 11" id="KW-0436">Ligase</keyword>
    <keyword evidence="3 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6 11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RNA-binding S4" evidence="12">
        <location>
            <begin position="352"/>
            <end position="409"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00013160"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00033323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048248"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00182"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU361234"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="SMART" id="SM00363"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2432307.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="419" mass="45067" checksum="8E7AB20422873CE6" modified="2021-09-29" version="1">MVTNTEELEAAAAAGRLSVYCGFDPTADSLHLGNLLGIVVLSWFQRCGHEPVALLGGATGRVGDPSGRSTERPVLSEEQIEHNVTSIGNLLRGILVRNSPAGAPAVRVLNNLDWFGPMAFLTFLREVGKFARVGTMMAKDSVRTRMESEQGISFTEFTYQLLQGYDFVHLCREHGVRVQIGGSDQWGNITAGTDLIRRLLGGEDKEAPACYGLTFPLLVDSEGRKFGKSVGGAIWLAAERLSPYKFYQYLFQVTDADVVKLLKMLTFLPLAEVEALEAAMKAPGYVPNTAQRRLAEEVTRFVHGEEGLAQAIKATEALKPGAATQLDAATLETVAGDAPSASLPRAAVAGATLADVMVAIKLQPSKSAARKLIKGGGVYLNNAKVGEELYVVRPEDLIDGRLLLVAAGKKNKMLVRIVD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SST5</accession>
    <name>A0A835SST5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">t(6)A37 threonylcarbamoyladenosine biosynthesis protein TsaE</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HYH02_014882</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TsaE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000110">
        <property type="protein sequence ID" value="KAG2426020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SST5"/>
    <dbReference type="OrthoDB" id="10259622at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047627">
        <property type="term" value="F:adenylylsulfatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002949">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine modification"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.428.10">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019808">
        <property type="entry name" value="Histidine_triad_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011146">
        <property type="entry name" value="HIT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036265">
        <property type="entry name" value="HIT-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003442">
        <property type="entry name" value="T6A_TsaE"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33540">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN TSAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33540:SF2">
        <property type="entry name" value="TRNA THREONYLCARBAMOYLADENOSINE BIOSYNTHESIS PROTEIN TSAE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01230">
        <property type="entry name" value="HIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02367">
        <property type="entry name" value="TsaE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54197">
        <property type="entry name" value="HIT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00892">
        <property type="entry name" value="HIT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51084">
        <property type="entry name" value="HIT_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="HIT" evidence="13">
        <location>
            <begin position="26"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="128"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="360"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="138"/>
            <end position="161"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007599"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00019010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00032441"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00464"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS51084"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG2426020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="450" mass="43984" checksum="58233865B31E3739" modified="2021-09-29" version="1">MAPGSKPAPLVGVTDYRYNERNIFSLMLQGASGGLETPIIFDSAHTFAMLDKFPLARGHSLLVIKAPVATLLEELNPEVAAAAFADLQALCRALVAATGCAGLRVTQASGPAAGQTVPQLHFHIVPVYSSSSPPPPADSSDTAAAAAPGASGAAAPAPGAADADADAASSLAAATTATTTVRHQLLPAEAGPLLAAVRNRLPPGYAPGYHAWAADEGEMEALGAALHQAFGQPGSVIALSGQLGAGKSTISRGFVRAFARDPLLAVPSPTFLLCLSYADDTAHERRHEGAADAGAAVGAAVGAAVGAAVGAAVGAAVGGGSSENGSGGAGEAAAAAAAAAAGAGAAAAAAAGGVAAQPAVVESGSGSGSQQDRAGSVHHMDPYRLGGGSKSDKMAGLIDFGSAFSKDVCLVEWPDRMPGSVMAMTAGGLAVDVSGMGAQVGLWVSVFWIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835ST31</accession>
    <name>A0A835ST31_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_013345</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the TPPP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000073">
        <property type="protein sequence ID" value="KAG2431356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835ST31"/>
    <dbReference type="OrthoDB" id="548799at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001578">
        <property type="term" value="P:microtubule bundle formation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046785">
        <property type="term" value="P:microtubule polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032273">
        <property type="term" value="P:positive regulation of protein polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008907">
        <property type="entry name" value="TPP/p25"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932">
        <property type="entry name" value="P25 ALPHA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12932:SF9">
        <property type="entry name" value="TUBULIN POLYMERIZATION-PROMOTING PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05517">
        <property type="entry name" value="p25-alpha"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0106">Calcium</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="442"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="4">
        <location>
            <begin position="484"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="674"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="44"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="727"/>
            <end position="750"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2431356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="877" mass="89687" checksum="794D9D5B182E148D" modified="2021-09-29" version="1">MGLFSCFAARPAPDSPREASLPVSSSMRVPPNMVGKVASGRSTAPAVAPTPAAQLPPAASTRKQVSLALPDPDDDIDVGPATRNHVDQTPKKTKPAALKATAAQAAADQDCDVAPPATDAGTFPAATSASIRRDAAAAASGSPSAEAPVSPLAGMNARVPSKVVRNLSAPVLTLADIAGLLGRFTGSGGDSDAAAVTAYLSAVLAGSKAQGAGLYEAARAQPEAGKVFAAAYRLAQVAGQVVPTGPCRDNGAVMAGLGQDVVRALDAAGKKGCVPPRETLADVAVRLDTCSHCLSVYAKEGWLLHLACNEAAKADLDRAHNAVVAALQAVAPGPSGLELPVGSSAGRPGAYLDMNRGLRRSLKTHGSGSVAAGLKAVGTDPLSPELTKLAALLGVSAAAVARELAALPADVPADVYYSRMVLSLQQQRTLFGSAAGADATASLVERYRPIFAHYDKAGKGYLEAAELRAVLGDLSEAGAGGAGPTGPELERAFALADQDGDGRVNPEEFARYYDALTFGHARKQLRLAMGLQAENDLKALFRDFASFGTRQQVEEMDSAHFAKLFRDCGLLGPDLTLTDIDLAFTAAKGKGERKLSFDAFLTALATCAERKGCGLEGLVRSILGSEGPLARATKADAVRLHDDKSTYTGVYAKGGPKVAEKAHDLAALLDRSDAGAKKTPVRASRAGPITIVDKPADKPPLHHTPPPAHAPGAHSQSMRLSMGPGGVPAASVSAGGAAPSANNAAAGGSSWKRRSTAGGSGSVTAPSTSTPLYESWLMWQQFGAGAVAGAPSRTVEMGPAQYVKLLRETGIISGKDFTAVQAELIYAKVKPQGCTKITYECFERALALIAAAKGTPREALEAAITASGGPLLTPCKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835ST58</accession>
    <name>A0A835ST58_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="5">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_014130</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000087">
        <property type="protein sequence ID" value="KAG2429198.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="551459at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000785">
        <property type="term" value="C:chromatin"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006338">
        <property type="term" value="P:chromatin remodeling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050935">
        <property type="entry name" value="Bromo_chromatin_reader"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880:SF225">
        <property type="entry name" value="BROMODOMAIN-CONTAINING PROTEIN BET-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22880">
        <property type="entry name" value="FALZ-RELATED BROMODOMAIN-CONTAINING PROTEINS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032715921" evidence="4">
        <location>
            <begin position="23"/>
            <end position="1419"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="268"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="305"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="351"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1226"/>
            <end position="1248"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1260"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1334"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1373"/>
            <end position="1396"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="21"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="394"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="515"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="616"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="759"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1103"/>
            <end position="1133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1151"/>
            <end position="1192"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1089"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="21"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="394"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="446"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="526"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="639"/>
            <end position="649"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="759"/>
            <end position="770"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2429198.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1419" mass="144208" checksum="4176B21C53C1C19E" modified="2021-09-29" version="1">MLRLLTVRAMATVLVTWVATQARSGSGNSQSSGQPSGTSAAASAAAAGVTGAAAAVNSNSSQQQQQQQQQQQQQQQQQQQQQRQPGVVDPSCTQQGPRPHAQQPASENTCDAGARSGPELGWRSALLRALGLERAPPEEAEARAAFAESFALSTSRTGQCTDLLLLASGVVHGWLLEGRHPLSADNAYALLYLGPGAACTLARLLAPHLPLLVPRPLAMRASAAAEPLSRACRLPRLGLQVLVKALTATRVLPVPASLMTSYFRGPSFLLFEGILLPVTGLVPLWAAAVLALVRTPLHFGNMRVAALGPTAAAAAATAATTSVATAATAAAASAVGTAPGAAAVRLGPAEAWLRALGVELLALATCLACHTYLWREWGRRRRREGWRRQGQEHLGQGLLGQGQQQAAKAVDSESEAAPAAGKRHVRTAGPEAAAAGSSGVTPSHWHQLQQRQGQEHNQGQGQRQEHLERQPRQRPPPYRAVCRRSSLVIKIPWAEPEDLHPEFRRRLLALAAASGSSSHLGGGGSSTQQQQQTGSSSSSSSSMVVMAAAVRRGCVELVMVLGVQRWEPQQQRQLLLQLPDGAVSGSGSSGNSGNSDGGGAGCSGSGGCGGGGSTGLPGHQVALGPAGAGDGRSSSRRSQGGGDVSGGSSGSAAVALPFSLPELLGALGLMGAQGRPQVAAAGAVNGNGGGDTGGGAADRLASKDVRQLLSEVQVRVWDLDNGGSSSAGSAPTPPELRVQGLGPRVVLLPAPTSAPAATASSEAACCSNSSGGHEQRDPGEAAQQQLPPLPPLVLRARLGLGPDWDAGGGAAPEVEVEAGLMLGLAGLAVQGRSLPCCPQCLPASVRLLGPVCLRQAAAASAAEWEVEVEITVELGALRPTPGGMLLDVRVHQPASAAAADTSAAPAAIAAPAPDAHGLMRRRACVPLVATADSDLAAEVTSLAKGWPDPDGAGLESFLFDLGYCLQAAAAAEVAEAAVAAGADVAPEAAVAEAELGNAVGRAVAAATTMKTAAAAAAAAEAQLQAEVGEGLLDFVRQVDSPCGDLLPATTTQLGACVALLRRRAAQLLQQEQQRQQQQQQQNAQQVINQVATQQELQREVQRETLASDQDRTINGKAQSSIVGRQGGKSAPAKSAAASPALLIGKAANAGTTAGGSSNGASEGKHGFSKQASGCPHADSPSSSGATAGSHWDGGDGSWRTALLCVLGVRRIPAAQVQAFTAFADRAMLPAILTGHLVDAVVLAAVLGGTLRAGASPLDPVMAAPLVTLGLGGAGALAQLLLPPRQAERVGWSLRLPCQVSAAVVKALTLARALPHPLTSRAYYGRLAYPLREGLMVPITCLVSPAAALAVSLLKGPVNAAMLLDLGAAPHPAAALLRALGVELLALATCLACHTYLWRECGRRRGYVGPGGPGAGALRN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835STU3</accession>
    <name>A0A835STU3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_012793</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000064">
        <property type="protein sequence ID" value="KAG2433089.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835STU3"/>
    <dbReference type="OrthoDB" id="558858at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2433089.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="628" mass="63750" checksum="DCD65B47EC32ACAD" modified="2021-09-29" version="1">MAEAAMVAVRAVSRLVGTLAGGLLLVWVISTSRLASGAHESVAAAAAPQAPEVGLVQHPAASKLPHLTVNGPAPAITTPAPAGAETATTQPATAIHVSTAEAATTKPTSLITQQQQQQQQQAVVRRAPVPTPATKKAIKKGMRKVLKKALRKIRLSAPCAKVAVRVLEAYDPAAAAGFALAGSAAVQKAVVVHSVGELVKAIHSSSGHAAAQIYSLAFTSERAHAAQQLAFDREVAAQAAQGVAVFVVVLGADFAQRAKLAAAEYCGRPELSALGAALDMQGAFGPDVALASLLPGAHARKDFMPPRLPCIAFGGLHQQSDVMWEAASAGPFVSTSDVDAETWALAAAMRVLPLSAPATLADAAETRRAQLHQLSCLQSKLQLGRQQQQQQAAGGGKIELWNAGYAAAARAATALAEAEAAEAEAVSIFSSSPSPSPSSSLSSTAAAYLPADMSHLVPTSEVDYLRRHAAATAAGKLLAVVRVSEAAWKDHGPAIRAALAAAAPCSSSSSSSFSSSSSSSSSVWAEPVLLPVGLGACGAHSLAIAAAGAGATAAAAAAALPALHVGGGGYLAEHWSAAADLLSGQAPAAGLSDMRQAIDLHAMRQRAWLRRREAVEAVVAEEQVGLMY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SV74</accession>
    <name>A0A835SV74_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014266</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000090">
        <property type="protein sequence ID" value="KAG2428854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SV74"/>
    <dbReference type="OrthoDB" id="10604242at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="30"/>
            <end position="39"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2428854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="177" mass="18564" checksum="AAFE7441CC295B44" modified="2021-09-29" version="1">MSTTTKAPAPPRPPSDASAAPQQPQPQLQTRAGSATNPPGVNVPPAELRRLMAAICELRDGGEGEGGPGSGEREGEGNGVLDTALVISRAIDRYHPYWVASRKDWKEEAATAARPAYPTAVLQPHHHMRTYGVHLRQGVMLALTPPGDIHSEAGRWTAAQAAAAAAAGGGGDEVRWE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SVZ5</accession>
    <name>A0A835SVZ5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_012353</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the CDC50/LEM3 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000058">
        <property type="protein sequence ID" value="KAG2434332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SVZ5"/>
    <dbReference type="OrthoDB" id="340608at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005045">
        <property type="entry name" value="CDC50/LEM3_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926:SF0">
        <property type="entry name" value="CDC50, ISOFORM A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10926">
        <property type="entry name" value="CELL CYCLE CONTROL PROTEIN 50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03381">
        <property type="entry name" value="CDC50"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="469"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="68"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="243"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="365"/>
            <end position="399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="68"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="99"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="243"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="254"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="365"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="387"/>
            <end position="397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009457"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2434332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="504" mass="50856" checksum="D6BCF40249988383" modified="2021-09-29" version="1">MRRLREQSYDTWRPVPGLGRAVAVMAALAALGLGLGLPLLVASLRDAPQVRLRYDNAPLLQPAAACGNGSGGNGSSSSSGGGAGWDPVRCNRPEPAAAAGGGGGNGSGSGSGGGGAAAEKQAAIWAAGAAGAVQEVWVTLPHDLPPPVYVLYEIQVDGAGGRLGGWGLYGTHKRYLRSVSREQLAGQQPGPEALAKCEPQLYVGGTANASLPAAGLINPCGLRAASLFNDTFTLHADPATCGGAGGSSSGGEGSSSSSSSSSSSSSSSSSSSSSSSSSSSRRDGGGAAGATPAGQQPQPQPQPLVEVALHRGDGDVVWALERRSLYGHPYNSTNFNPLPALVVPLTADSHWRRLGGPLQLVEGQQWGQQRGQQGQGQEQGQQQQGHEGPGPEGGHQGVVGADPALEVWMRPSARADALKLYGVVRQHLPAGCRLRLGVAARYTGPYSWGGAKAVRLAAQSWYGLRAPGLVVAGALLGLAGAAAAGAALLLALAAVRGVRGRRGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SZB4</accession>
    <name>A0A835SZB4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013516</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000076">
        <property type="protein sequence ID" value="KAG2430984.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SZB4"/>
    <dbReference type="OrthoDB" id="439326at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35738">
        <property type="entry name" value="OS05G0577800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR35738:SF3">
        <property type="entry name" value="OS05G0577800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="334"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="361"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="293"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="315"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="367"/>
            <end position="389"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="442"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="483"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2430984.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="625" mass="62332" checksum="DF5DDB4FCDDF4705" modified="2021-09-29" version="1">MANNSWTWANAWATVAPYIPGLTGGAGVQPEPPPKVVLVPPFFQRDVRGLSRFCRSSYDYLASRKQLSRLLRDHLQPEVRGGLLLSPPDDQRVSVRARLRHGGGSMVLRWQPGGAAQLHTFLELAAALDSPGHVQFRAAYLHPHSGLGAFVVAPLLSAAGAGAAAAGAGAGGGDVGGGVGGGGSAALSAVGLPKAVTGPGAGAGAMGGPEPAPAAAAAAAGTCAPQVGVRYSSEALAAGAIVSASGGGGGAELERAWLAARTPQGLTLGLELRPAAPLHQLAAAAAEGLAALRGGSSSSSGTGAAAPAHPDKAGTTTASTSSSTPSASPSPPAAAAVLPPLAHLGGWLRARSSLLLAYSPPAHHRTQQQQQQQQGAAGGSSPASPGSSSFTAAVEVAGGRRVTFSFFQHVAATRQVVNPFEENEVVGITNYLDLGLQLTTAVGSGGQQQPPTAGAASPPKQPASSSAGGAAPSSSAAPSSAGPATAAASSVDLAASWQINKNWIVKARVGSESAAAAIGVRAWHVVSAYLTASVGLDWATRTPRYGAELCVENWGPLRYERGAADVAAGRALLQRHEASPQELANRAGRGVLVRRNVDADLAAAAAVAARGGELEAERQRVAALM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SZB8</accession>
    <name>A0A835SZB8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_014119</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000087">
        <property type="protein sequence ID" value="KAG2429185.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SZB8"/>
    <dbReference type="OrthoDB" id="202415at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="3">
        <location>
            <begin position="79"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2429185.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="414" mass="48012" checksum="4AFAE57FC6B8C312" modified="2021-09-29" version="1">MLNETKVWGDKGITKDLVDSLHTQCPPTEVRTHACVKSQRFLIKDGTVYVTNLMPRNGFGAIELIGFLVELYEVSQVYKLPDVEFSYWHDDNAPAETIQKPDGTWTWPFAPHGLPPILAWAKAKQHGALLVPYSGAFRCPRDSFDAIMTEVQRFSETPWQKRSSLAFGRWNIFCAWYYRGAQRLEDGTAAPCPRDYYNDLYYNHSDKIMTLGLLRNYTNGTTALPLSLHEQHKFKYLVSTDGWAISSKFDKYLLLGSLLLKAEGQTYGWYYPAIKPFEHYVPIMKKHKDDLLDMLEWAKSHDKEAERIGQNAQGFAMRNLNRQMRLCYIARLIQEIAKHTKYKPDCSNRPVCVPLVEEIKFLGKYEETRHKCRYQEVLTQYAHDDPDARPGESGFEDLKKKHEAMPLHIQFGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T2P2</accession>
    <name>A0A835T2P2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_011102</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000045">
        <property type="protein sequence ID" value="KAG2437724.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T2P2"/>
    <dbReference type="OrthoDB" id="547660at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="9"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="61"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="226"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="9"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="231"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2437724.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="314" mass="32657" checksum="28F10DE54524528B" modified="2021-09-29" version="1">MVISARAALGARAPGAFDPPAYGGYGGGYGGSPPPQYGGYGVSPPPYGGYGYGGPSYGHYAPSYPPPATSTPPYNAPEWPPMEEALERPPASPEPPPPELPPAWLSPPQSSPPPPAPPPPSPPALPLTDIVGCYQFLGPGGRRLFPANELSAGHGSAGGGVGPNAGPRSFDAAACVRVVANSGSHSRYVGFFNGHMCFGIGGILPPSALASEQPFAACDPCPLTARNSTSGGSGSGRNGGNDDGSNNHQQGEPQPQQLRCGSDTRMAVYDLASWPWVHLAPMLPPMAPWPPEPEDFGRRRRLLRSRRRLRQRTA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T2Q1</accession>
    <name>A0A835T2Q1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">DNA mismatch repair proteins mutS family domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_011115</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000045">
        <property type="protein sequence ID" value="KAG2437739.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0006298">
        <property type="term" value="P:mismatch repair"/>
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        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043504">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000432">
        <property type="entry name" value="DNA_mismatch_repair_MutS_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036187">
        <property type="entry name" value="DNA_mismatch_repair_MutS_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045076">
        <property type="entry name" value="MutS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361:SF34">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MSH1, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11361">
        <property type="entry name" value="DNA MISMATCH REPAIR PROTEIN MUTS FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00488">
        <property type="entry name" value="MutS_V"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00534">
        <property type="entry name" value="MUTSac"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48334">
        <property type="entry name" value="DNA repair protein MutS, domain III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00486">
        <property type="entry name" value="DNA_MISMATCH_REPAIR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032531972" description="DNA mismatch repair proteins mutS family domain-containing protein" evidence="5">
        <location>
            <begin position="32"/>
            <end position="824"/>
        </location>
    </feature>
    <feature type="domain" description="DNA mismatch repair proteins mutS family" evidence="6">
        <location>
            <begin position="558"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="98"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <begin position="239"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="422"/>
            <end position="448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
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            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="708"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="125"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="241"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="266"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="429"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
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            <end position="523"/>
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    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="736"/>
            <end position="749"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
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        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS00486"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2437739.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="824" mass="83058" checksum="0AF31C9491533E18" modified="2021-09-29" version="1">MARPAAEVVSRCRRGIGALVQALLLLRGVLALTEPLAQALEGAQSPLLAAVRANCRNPHLGQLRARIDQVLDNEAAAATARGGPFVSRVQQCFAVSLPGGSSGSSGRGDAAMRQEGEGADVGAGPDEEGDEGDEGEAGEAAAARLLQRRTQAWRQRGQGEEEAAAGAGAAAATAATATDECGGLLAVARGSLCRLTEAVHELGQRYGQQWALPLKVAYSGRKGFYLTLNQQQAAAAAAVGADGGGGGGGGRGGRGRGQGRAQAAHPHPHPHQHPHQQLKLPPELLVLERRGRGTLVLTSHELNALNSRLRDAIGDCLLLTRQLLEAVVVEAVGGGALPALQRLTDGVALLDMLVGFAAAVAPDGPLGPCCRPQLRPGGPLAIVQGRHPLLQAAANGAFRSQQQATAGSRYGGGGRGAAAAAAAAGASPAAPPPPPPQPNDTFLSPATAPLHLVTGPNMSGKSTYLQQVGLLVVLAQAGCWVPAAHCCLPPFTALLGRLGTAVQGGGGGGGGGGGGGGGGGGPLGSSWAPEDDLESGRSSFVTEMQDAAHVLSSAGPRSLVLLDELGRGTATADGVGLAWAIAEELLARGAPTLLATHFPQLAELAVLYPAARLWKLQVDTSGGELDFRWLLQPAAALDYCHYGLLLAAAAGLPEAVVREARRVATLLEEGERRRLELCAADSADWAAAAAVCSRLVMLAQQWRSSHSGGGSSGAADLLPPPGSRDDSAAVAAGAAGAAGAGEAAGGTSGTGDPANYCEEGDEEMTELLGEPQAAGGASRPAQKRRRSGGDEAAEQQVAALLEELRGLAEAALQLTAAVRYGASS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T325</accession>
    <name>A0A835T325_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_013669</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="7">Belongs to the adenylyl cyclase class-4/guanylyl cyclase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000078">
        <property type="protein sequence ID" value="KAG2430671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10658505at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="project" value="InterPro"/>
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    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Guanylate cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="A/G_cyclase"/>
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    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
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    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00452">
        <property type="entry name" value="GUANYLATE_CYCLASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="10">
        <location>
            <begin position="2443"/>
            <end position="2584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
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        </location>
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            <end position="1464"/>
        </location>
    </feature>
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            <end position="1538"/>
        </location>
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        </location>
    </feature>
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            <end position="1690"/>
        </location>
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        <location>
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        </location>
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    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="2118"/>
            <end position="2200"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="8">
        <location>
            <begin position="495"/>
            <end position="522"/>
        </location>
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        <location>
            <begin position="422"/>
            <end position="443"/>
        </location>
    </feature>
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        <location>
            <begin position="446"/>
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        </location>
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        </location>
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        <location>
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        </location>
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        </location>
    </feature>
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        <location>
            <begin position="1997"/>
            <end position="2018"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="9">
        <location>
            <begin position="2035"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
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        </location>
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        <location>
            <begin position="2120"/>
            <end position="2138"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2430671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2647" mass="261287" checksum="343126F9F1E40878" modified="2021-09-29" version="1">MDSSRCTLPRAAWESARGTGDSPSALVPVQQQGCSALSLGQQLEQLRLQLAPGDASVLLSAAAAAAAAEADNALAAGDGEGCGAGALGPQDVALAGTAVGVTVLQLPRNAYSGGKILFQNPRSKMWAGDLEGQPLAYELLCCLFSAAGASNVGAAAAAGGLGGRAAAASATTAGTACIVDDGTAPPPAVVGALGGASVAGSAHPPTTPVASRAANGLMLDAGAAAAGSAAAAGAVSAAYPGAPAASLASTTAAATASGTGTGGAAGADALDLLVAMLRDLEAGREFEMTVEVPASLCNVRHYLPTATADVNVGSVGMCGSGSLASPLLLPGVQQQQQQQQQQQQQQQQQQGAAAAVHVAACSLLRSPRTTPPGLRQPPAPAAAPAAPVSPVVAVAPGGATADSPAALVTESRAAPLVIPSSLSETASGAPPHTSQPLSVNRSAGSAAAVPRQARHAASVGLPGQAGPPLLAPHLLLQHVHQVPQVQQSMRPGSAVHAQQLLLQSQQQQVQQLQRRLAELMTIDSIGGGGGSGQQQHVVLSGGYLLATDESVHAGCGLLDSEDRRLLDALLLGTDDCSAGKESGAGSAARTAAAGACGGGGGESGGSSSRGGGGRPVYGGRVPVAGLLQADSGPAPLVMSGSGGESRDVRRPAVRRSISLQDDYFAPRCQAAALAAGGRRTSSRAVRQPSPLSTTDFGFGLLLPPRHGGGGSVTAVAAAAAAAAISVTRPPSSAASGMTAGSFVSGAGNSQAGRLARTTSHSMLRMSNGAAAGAAAAGGGSVVGRPAGGGRAAHVTAGSNVLGPTTLVGAARMSANSSSGGFAMAPAVTGGAFPVSNNLLAAASVGGRRPFARVTGAGLSNAGSGSGSPRSGVMGVARTLSTNQLAALPGAALVTPAALAGDGAAGPAAPPCSRCSDSQLQVTSMAHALAPCSSTGVAGDGGGPHRDTSGPLGTAGGPTTQPQLSRLALARSSSLYTPAAMPRARAPTAEGTPGGGAALRSGSSLSVALPSFPTLESAVDAAAGKASGQQQAAAAGSTARPAVGAPPPPMAAVAELAPTESGDATSLPSLVAIGGASGALQSNAASSAAASLALAPLVADSGLSTSEPAITLFGLAMKQGTSAGGTAVGAAAAAERPTELGAGTLEMHSNRPAGAAAVAAGPTRQLLRTPDGGSSRELALSPAGPTGQVTGPPAGPEAAPAAVRRSRLSCSEQLPVLRPQQEAVLGLTLALPDTATAAVETTRQGGEAAGQPHFDPLMMKSVLTPTLAASEVATEAAATKSTAAAAQAAAAAVAAAAAPDAADAQPASVAAYSSIIPQPAANATAAVAVAVGCSSGGGLFQETGSLTLATIRTAASGALAEAAVTAASAVFPPPPSAVGTAGATQPQKQHSQQVAAPAAHTASAAQPGGLPVADPALPPRQVQPEASGLQAAVEEKMQAPMPFHQQEQPSAPGSPCGPPAMSPPADGIAAIAHAATGVRVRTSGPKARSLLVLTGSGRGNGGGDSFPVSGGSESTGRAASSTAGGGCMEEGKGSNNSNAPTLHQVLSLVQFARSGSAASLLLADDRSQSRSQPAARRLLSGLGVEPLLVGADSNGGDAAAAAGASAAMSSGGRGSNHSNGGGSLLFKPPHTAADALLVGEPFSLLGGGDMFHRGTAVAQPPSIASSAHATPQASVQRHGSSSAQEADISSSVGVASGPTALLNFLPYVRPVMTPSAPPQPNLRPQELHHQQQHHQQLLLVQPHEQQQQQQPARHKQAGPQQQQQALVEHRDVSVAGLAHQEHLLLLQPSQTHTIQTTRQHSNMGSVQSSMWGALARGGESGPGGQTLSVESYATGSASATASAPGAGEGVLLAAAASTAAAAAALALGGGEASGGGRSAAYRGAATGPAGGGGGSSRRNVHLGHMTDDGSIAAGTAATDPAAAAAGGAQVEQPDSAARIAFNGGGTFAQLASACSAGYESPSNSSSLYGGTRTPGSVAVQHHLPSSPIPRQSQHQHEQPQAAPQPLLQLQRQQSQPQQLWTSSGGLAPPCTSPVTAGGGGTAGGGGTSMSAGLSGAMLVPGNAAAGTGQHGGSAGSSAGRAQQQQPAQQLAALSSRSRRSTLRSQNTGRRLHALLTSFSYQQQQQQQQPHQGMASPQQQRQLQDHSAHSAAPSTTGVAAGTMGAQALQQHRSSEQQMERQSSLPPAAVQTLAPPPSAVHGMRYRRSSFPSAQELASGLASAAMASVAPAAVVGKGSGAVVCVSGADRDGSWAEGEAAYALAASTAAAAPTAVTAVEDTARPSALVPAQPGTAAAPSTAHYWPPRRMWHKVHIVRSRTPAAGEPCATVRPGEAGRAAATATSGDAAAVKERGGLGDALTLTVTQIDVTEQVEAQARLAKLLEQEHKILEGIFPRHVIEYLALADTEGTAAQNLAAGAPGGSSFLTFKPGSVERMASLATWHEGVTILFADIVGFTTMCQTTPPLTVMAFLNLLYSRFDAMIDIYKVYKVETIGDCYMVAGGLVHYDDDGYKSVISGGEDPLHAVRVMEFAKAMLRAARDVRLPTTGEPVQMRIGLHSGPVTSGVVGDRMPRFCLFGDTVNTASRMESTCRPGTIRVSAPTQARVPNEPWHDCGMTEVKGKGQLQTYEWAGDVDSPYDGKQLQRVLGLYV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T414</accession>
    <name>A0A835T414_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011894</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000052">
        <property type="protein sequence ID" value="KAG2435603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T414"/>
    <dbReference type="OrthoDB" id="548729at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.20">
        <property type="entry name" value="Apolipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="705"/>
            <end position="746"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="763"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="10"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="364"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="441"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="564"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="713"/>
            <end position="724"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2435603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="803" mass="90861" checksum="D3DD9740D8E37D38" modified="2021-09-29" version="1">MSTIGTSARERELQSLLKQKDAELKQANAELEERGKLLYKTKVAIEQLQQELTASRREEQSIREEANRVCEDQAGQLRQAEEQIHALEEQLQQATKQSKELQAKASSYESELEHFRHQTHVEGSSAAQKLRDKEKRISSLEEEIEAVKEHAEGLEKMLRDSRSRLATLELDKEETDRVIRDLTAKNKQLSMDKQELEHQLEVAKSLADAAKREAARALQAAEVGEKEKTAIDIDWGRKVDKMTADFADKLRESERKLRDLDAEWKAKQEAAERSWVSRMQEVEQHWEKRLRDGMMACERKFAEEATEWERRLRDTDTAWQAKVVELEQLWRVRLTDEQRLHDADRAHWEAQLMAQRADLEASWAARLDDTRRSLEAALEEATQRAASERAALEQVAASERSALLQSAAAERSSLEASAAAERSALERSAAKRLEEMETLAARRAEESRAKWAAERAAAEEAWANKTAEVEAKYRKKLDELKRKAASRELEIDTQWKDRLDEATRKAAAERELLGANWNARLSAAQDEAAARYRALQEELDNKVAGISNRLADMAGKEGRREVQRTELARQVEELQALHETETRRRTELERALRDAAAMFKAELYDKQAELDAAYRDARSMRQQLALQQVIVTSPRLRNTLLQEEQAPSLSPGLATMGTAATPAPAGLGAAAELDAELQALRVARSEYQRSITAAHDARSGLLGTLDRTETYTDPRTFSPSNSPAVNRLLRPDTRQPQRSPSAGSRAAKYIDRLLLDEELAAAAADTRRDSTSTASADPSFDAWRNRLSTRLTSALKKLEPTGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T4S1</accession>
    <name>A0A835T4S1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_010717</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Prevacuolar compartment membrane</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the VTI1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000042">
        <property type="protein sequence ID" value="KAG2438922.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T4S1"/>
    <dbReference type="OrthoDB" id="430637at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012507">
        <property type="term" value="C:ER to Golgi transport vesicle membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031902">
        <property type="term" value="C:late endosome membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000149">
        <property type="term" value="F:SNARE binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006886">
        <property type="term" value="P:intracellular protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd15862">
        <property type="entry name" value="SNARE_Vti1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.58.400:FF:000001">
        <property type="entry name" value="Vesicle transport through interaction with t-SNAREs homolog 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.5.110:FF:000002">
        <property type="entry name" value="Vesicle transport through interaction with t-SNAREsB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.58.400">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027027">
        <property type="entry name" value="GOSR2/Membrin/Bos1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010989">
        <property type="entry name" value="SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038407">
        <property type="entry name" value="v-SNARE_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007705">
        <property type="entry name" value="Vesicle_trsprt_v-SNARE_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230:SF26">
        <property type="entry name" value="VESICLE TRANSPORT THROUGH INTERACTION WITH T-SNARES HOMOLOG 1A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21230">
        <property type="entry name" value="VESICLE TRANSPORT V-SNARE PROTEIN VTI1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05008">
        <property type="entry name" value="V-SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028865">
        <property type="entry name" value="Membrin-2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00397">
        <property type="entry name" value="t_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47661">
        <property type="entry name" value="t-snare proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="200"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="124"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="70"/>
            <end position="97"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006108"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00060376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00397"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2438922.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="222" mass="24744" checksum="3C94ED42F3E664AE" modified="2021-09-29" version="1">MDDVTALFNQYENEYCNKSTDISRKITTASTLGAEAKRKKLVEVDVDIKEADTIIKKMDNEARSVAPDRQKQLQNKVKEYKADLASLKEQLQKARSTTSDFEAGRAELGLGMDYASSSAAQRDRMLSATAKLEQSDERLKQGKALLAETEELGTGILANLHSQRETIVRSRDTLHGADDNITKARKILSSMSKRMLQNKLIMFGIIGTLLAAIILIIYFKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T553</accession>
    <name>A0A835T553_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_010746</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000042">
        <property type="protein sequence ID" value="KAG2438953.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T553"/>
    <dbReference type="OrthoDB" id="10064100at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2438953.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="221" mass="22857" checksum="722D69A4206DC847" modified="2021-09-29" version="1">MRAKLLQPAAGIQSAQQPLAHPQQQMHAVLVPAYILPGAQLQQPLPMLPPSHTPLRQHAVHPVTHAQHPKQPCAPSGGGFDGRCHGGGYAGGCCGGGGVDDDNASSVSRKCSNGGGGLGGRDVISASSSAGRGSTALVAEYCRLVERLRAHLPLLRAQIAKYDKHAQRSSGEAGIKASRSRRILEEAHKRCTAEPGSAAAASYPITGAAWEAPHESQVGAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T662</accession>
    <name>A0A835T662_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tyrosine-protein kinase ephrin type A/B receptor-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_012741</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000063">
        <property type="protein sequence ID" value="KAG2433200.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="553385at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00185">
        <property type="entry name" value="TNFRSF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.50.10">
        <property type="entry name" value="Tumor Necrosis Factor Receptor, subunit A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009030">
        <property type="entry name" value="Growth_fac_rcpt_cys_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011641">
        <property type="entry name" value="Tyr-kin_ephrin_A/B_rcpt-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07699">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01411">
        <property type="entry name" value="Ephrin_rec_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57184">
        <property type="entry name" value="Growth factor receptor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="1375"/>
            <end position="1400"/>
        </location>
    </feature>
    <feature type="domain" description="Tyrosine-protein kinase ephrin type A/B receptor-like" evidence="4">
        <location>
            <begin position="1019"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="336"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="534"/>
            <end position="591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="684"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="915"/>
            <end position="979"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1230"/>
            <end position="1325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1337"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1407"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="341"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="550"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="571"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="686"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="702"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="924"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="945"/>
            <end position="956"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1247"/>
            <end position="1267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1279"/>
            <end position="1292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1337"/>
            <end position="1351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1352"/>
            <end position="1366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1407"/>
            <end position="1421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF07699"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2433200.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1471" mass="148007" checksum="36FEAD1E67CDBBDE" modified="2021-09-29" version="1">MPIAPISLFTSPACTGFGFPGVITSCTLRDGATFGPALPALTYNLTANTTLVGRTDLPWPHAGGYLGGAPGWPPLELWSPPAPHAVWPFLRVPPGLRLTLTGLTLSAYPPYTTNRRAFSKLLGPDRIRAALLPAVLALVRPASDVLLGSDVASLMAPPAGSGGELALVNVTAQLPDCEVWEAVRQELCLGGQVFSDLIHIKSFSRYGFTARDVFLTCLNTSATPWAGRQLAWPPPPPSPPPPMYTSWRPVVAGCAATVESASDLATVLSKANADDLPVYDEAQDDPPFAIRIRGAVRLSELLARAGSSAGLLANGTLRLRRAFHLWGRDTQGAVFLDDDSGSSNSTSSGTGTGTSSYSRLDLGGLPHPFAFQLLNPPLNRVDSLRQMTLRLTGLTIAGLAPGDPSTIPHGLLTALGWAFGINTAVTERSQSQISSSLLALQDCVVVVGADELAYWRAALLRLTQGGGGGTAAEQAVVALSGASARQWSDWMYSTMNAQVSNRSSSSLTLLYLYFPAETFPTVTWNNVTLVTPADPRAGSPPLPASGANPSISYTTTTSQTASSTGIGPAEGGSEVSSSGSGVSSSGSAEQGATTWEPLWAGADDGWLMRLAAAPEAVLVDVQAAAGSAGAATADADGAARAATAAGWKTLPLSRVPTVKGNIPTAGWTTAFAAFVKDPSYLDDSVRSGSGSSSSTSPPPPQSGRSAAPIASTAVATSGATAGDPAAAGAGWSQPVFIQEYSFIRMVDIKWEVGRLLLPPLEPPLPRKAPRAAGGINPGGGGGGAVSTGGRLNTGAGVRRLRRLQAWHHRHGQQQQQYGSKQRQQQAQTRARLLEHWDRRRRRALLGGGVVMGDGGGALPSLPVPGNVTLFGHPWFPTILDLSDMASGLNLTGSSAVALRQLVLVGLAGGRVTRLAGALPDSGTGADGGGGGSGGGGRGGSKGDPPVDPPSEPPAPATAPRLVASGGGNTPSSAGARRRRRLQRASGAYRCAPGSYLDATTQTCIACGPGSFQPQANSTAPACGPCPRGAFAPMAGSAACSACPPGLSSNEPGAGDCGTLWLPAAALLLFDFDRTYLLPARVFLRDVLMVLPEEELQVLLALAPKLFAALANDRGSNGTTAASTVVPASPSALATSAAVAAAVEEVASAYGELLGTEAAVRALAELLLSSEFEAPQRDGAADATGGSRGADRMGAQLVLRRLSYAGVRGVNVGITSRSAYGVADLQAGLGTPGLPDVPPGAPEVSMPPAAPPSPPSPPAMPPGPPRRLPPGVFQEGGALPPKPLDTMPPPPSPLSSGLLQPPRPPLSSQGSGANDRAASASSPSATVDAAALAGEAVGPSGSGGAAAAAAPTPGGGAGSSGGSSGGSSGGVYLQPWQAGVMVAGIVMGVAVAASLGGIILWNRCGPPPPPKARAPPPPPVPKPSDVGAAAAAATTGACTGAGGGGGGRGAAAVAGSSIELVDMSSGQGGARA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T6W5</accession>
    <name>A0A835T6W5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Agmatine deiminase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012888</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000065">
        <property type="protein sequence ID" value="KAG2432755.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T6W5"/>
    <dbReference type="OrthoDB" id="544103at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047632">
        <property type="term" value="F:agmatine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004668">
        <property type="term" value="F:protein-arginine deiminase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009446">
        <property type="term" value="P:putrescine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.75.10.10">
        <property type="entry name" value="L-arginine/glycine Amidinotransferase, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007466">
        <property type="entry name" value="Peptidyl-Arg-deiminase_porph"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31377">
        <property type="entry name" value="AGMATINE DEIMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31377:SF0">
        <property type="entry name" value="AGMATINE DEIMINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04371">
        <property type="entry name" value="PAD_porph"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55909">
        <property type="entry name" value="Pentein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="23"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="106"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="235"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="39"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="121"/>
            <end position="134"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2432755.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="568" mass="58063" checksum="A3F56DF6AD01AD8D" modified="2021-09-29" version="1">MAASAQLLRQLARSAAPLCLERGPPGPWPCMAAHRDSAGPTSSLSTTSTDANNAGSVVATAVPQSSPAATAIAQGCSSSGAAGPARARRSTSCLAGSASEDRIPLATDWLGSGTPSGGGSSNTTDGSSSSSAGGARDTPKARGFRMPGEWEPHAGTWMAFPHDCHLWRAGGRPAQKQLADVARAVSQFEQVWMLVDPRVRAEARAALRGVSGVELVEMRVNDVWTRDWGPTCLVRDLPGSSSDGSSGGGSSGRVRRRREVGALHFDYNCYGAPLKPYPLMPDWSLDRAAGRALPALAGVRAEAVWRAPRGLHLEGGAVLSDGEGTLLVTEECLLHPSRNLPPAGWRQQGPLASAGWGPEAAAAAAATGSGGPGAAAAAAAEAAAAALAAASGGERGAATGQQQQQLQLPAELERRQRKAEIGALLCDWLGADKVLWVPHGMAGDEEGTNGHVDNAAAFAAPGLVLLAWCDDPDQDPDQTRRAAENLAALADQTDARGRPIRVVPVPCPLPLVKVSGEEAGGAAERAAAVAAGYGGRLSAGARLPASYINHYIVNGAVIVPLFGGEQAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T6W7</accession>
    <name>A0A835T6W7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_010471</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000039">
        <property type="protein sequence ID" value="KAG2439838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T6W7"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="461"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="525"/>
            <end position="654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="218"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="284"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="496"/>
            <end position="505"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="546"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="566"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="636"/>
            <end position="654"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2439838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="654" mass="64964" checksum="DC3B9977BC1BFBAD" modified="2021-09-29" version="1">MWAMNLSVDGPPPRFTITSTRAWAGVDGRGDDTDSGAAAARIIGPPGSSSADILPFTPGTDSCTEMYAHEDVLSNQRYWHSDTVTTAAMPPASSTMPTAGGAPGLEQVSTANLIALMGALSGAGVLGRGGTDCPIGAAAASAGHHSASRSAAGASRDSPPLAAAASSRGTDCAAAAAAAAAGAAARQAHAAVPSSSKRPRSGEVPAVHDGGCCWAAPVGGGGEPQQTSSGGGWLPAPPPRSQQQSQCTLAAAAGHGDQQQWAAPGGRRHGRADNRDDQHPQPQPRHAQPAAGMAPAAAAEWHAGGTHAPAADSSCCTGSSRSHLSSAAHDMSVALSASHGGPSGPVLAHVRSHCPPPQCQQQDEVWIAPSRGASPRAAGAAAAAAAIGRQLWTAAGAGAGAGAGGYASCGATAEAPPSGRMCGAAHDAGGGHAVAVSAARVSSNGSTLAYGGRVSGGGGGGYGGGGGWPHSPARATGRDTHSVPHTSSHDNNAYCHHQQQQQPMHPQGPPCDVQAMSWVQRAGGRTQMVTSSPLATQEDGGDRWHQHQHHLHQQQQHQHHLHHHQQQQQQAEPRAAAELADPAAASGGSAPPAPPPPPPAPSSGGLCAGLPAVVEELLHQVDTVPRGHMESQEELSAAASSATTASSSSSSSGP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T6Y5</accession>
    <name>A0A835T6Y5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_012916</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000065">
        <property type="protein sequence ID" value="KAG2432785.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T6Y5"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006511">
        <property type="term" value="P:ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051834">
        <property type="entry name" value="RING_finger_E3_ligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931:SF3">
        <property type="entry name" value="RING ZINC FINGER-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45931">
        <property type="entry name" value="SI:CH211-59O9.10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 4" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="6">
        <location>
            <begin position="747"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="130"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="197"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="284"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="383"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="510"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="586"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="626"/>
            <end position="663"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="43"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="395"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="518"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="586"/>
            <end position="603"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2432785.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="794" mass="80165" checksum="663E15BE54803A0E" modified="2021-09-29" version="1">MAGAVDAVDLASTEETPPPRKRLRAEQASKEVLSLVDSDDDAGSPAAAARDAGAARAPDNYAGRLWGALGGHAGAAGGVAAAAAGTEAAGTGEAGPAAAAAAPLDGLGGLGRPLYRPPSARFRRPSAVGLAGAGQRGGMPAAPGPAVIDVADDDDDNDQQTPAAEASPQVAFVARLGIAARHPMMRRRYGVVDNDAAAGDEVDSGPAPGVDRASSVPQQQPHPHSRVRQRLVLPRPRVAGGTLAAGAAGASGAGGSSPEVAAGEAAAAVAGQPAWGMRFQTLDLGPDDVDTEPQRRRTAHPISGSGAAAAGAGGVGAAQEEGSDSPAMPLNARIAMRQAAARMAARQAGASGESASTDPMAAWARLSQRRLHLPDAYLGGARSKRTGAAAEQAGGPRGAGGSGAGGSGSAGAAGPAANQEEEDMRLAARLQAEEDERLARETARRLEQEEHRRMMSRLDMYEALEEHSQAAARRGRAQAAIAALEERERERAAAAAASAAAAAAAAAAAAGGGGGRSTAERQRREQELYGRAARARGPRGGSSEAGSGGVAGDAGGAAGAGAGPMGLGLPAGFPGLFMLGGGGAGGGGGGGGAGRGAGSGGPGAPRWSARALHELLPMMAGLRRGFVGMGPHDDDSDDDDDGPGFNPFHAPHPGNPGAHRRGRHAAYREQARAMRDQMLAAQRAGIPAHLLLSDRDFTPEDYEMLCRLDERVENRKGAKDDQLAVLPTEVLTAENPRRRSDGGPATCAICMEDLAPGETVKRMPCAHEFHDNCIDQWLRTKACCPICQRGLLDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T7X4</accession>
    <name>A0A835T7X4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_010350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T7X4"/>
    <dbReference type="OrthoDB" id="555745at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032340241" evidence="2">
        <location>
            <begin position="32"/>
            <end position="439"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="185"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="188"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2440469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="439" mass="45157" checksum="3F68EA833EDEE0D6" modified="2021-09-29" version="1">MAFPGRASSAPLSLLALAVCCAALLAIPARAGRLGVSQATSFLPRRSLLQGQCDLSCSQLSTCIKAQCLYSEGFASYVQIDLSGCKNNTISWYCCQRNSCTPTSCTGIGGVFLPTVNGTTCEGVNTSTVTTAIGATNVTLQVHDGRLNGNTNCSRSYCCSGNGGSCGGDNTCSNVTVAITGVSTCNNRPPPAPPSPKPPSPSPPSPQPPSPAPPSPAPPPTCGTVCRCNDTAWGFPLPAQFGSNNLSSTAELPLSISDAGFTSNRPSNAKVFWNAREYGGAWGGWFRILPPSNQGNTLNLGICAGCGQNVVDKGYYFGSGFSITFTNFAGGNSTLTIKAVPTGTLASIVGMQVYLSFIAPPDLNPGGFKTFTDYGPPVSATSPITSYPASGFYANVVPGALYKVNADTFSVPTSITSNGLFLSVHFDVGSYCPPGGVFP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T7Y3</accession>
    <name>A0A835T7Y3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Amidase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_006620</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000041">
        <property type="protein sequence ID" value="KAG2439096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T7Y3"/>
    <dbReference type="OrthoDB" id="245563at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1300.10">
        <property type="entry name" value="Amidase signature (AS) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023631">
        <property type="entry name" value="Amidase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036928">
        <property type="entry name" value="AS_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46310:SF7">
        <property type="entry name" value="AMIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01425">
        <property type="entry name" value="Amidase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF75304">
        <property type="entry name" value="Amidase signature (AS) enzymes"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="20"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="domain" description="Amidase" evidence="1">
        <location>
            <begin position="188"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01425"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2439096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="332" mass="34825" checksum="07AB2C7702C39A72" modified="2021-09-29" version="1">MRLAARGSRCAACRDAVQVAVAAGDVDIGLGTDTGGSIRVPGSFCGLLALRPTWGRVSSEATTALAPSFTCPAWFAKDAATLRAAGSVLLDPATRAPGSPRLGRWLVARDAFKLADPPTEKAIYNAMSADFDKVVALLGQPTEVDVAAPLAGQGLGQYVDWMGVFRVCQGFEVWREHGAWVTAHNPDFGPGIKDRFIMASGITQEQVDAANVKRALIRSHLLSLLGTDGVLAVPTTPGPAPLVNTPPAELDAWRTRLISLTSIAGLAGLPQVNLPIASVDGLPVGLGLIGPPGSDESLLELTERLMGVLPLWQQAQAQAQGQAARDPWQPKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T7Y8</accession>
    <name>A0A835T7Y8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Sigma 54 modulation/S30EA ribosomal protein C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_010168</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000037">
        <property type="protein sequence ID" value="KAG2440587.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T7Y8"/>
    <dbReference type="OrthoDB" id="10253151at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022627">
        <property type="term" value="C:cytosolic small ribosomal subunit"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
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    <dbReference type="GO" id="GO:0043024">
        <property type="term" value="F:ribosomal small subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045900">
        <property type="term" value="P:negative regulation of translational elongation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00552">
        <property type="entry name" value="RaiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.100">
        <property type="entry name" value="Ribosome hibernation promotion factor-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.50">
        <property type="entry name" value="Sigma 54 modulation/S30EA ribosomal protein, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050574">
        <property type="entry name" value="HPF/YfiA_ribosome-assoc"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036567">
        <property type="entry name" value="RHF-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003489">
        <property type="entry name" value="RHF/RaiA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032528">
        <property type="entry name" value="Ribosom_S30AE_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038416">
        <property type="entry name" value="Ribosom_S30AE_C_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00741">
        <property type="entry name" value="yfiA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33231">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33231:SF1">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16321">
        <property type="entry name" value="Ribosom_S30AE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02482">
        <property type="entry name" value="Ribosomal_S30AE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69754">
        <property type="entry name" value="Ribosome binding protein Y (YfiA homologue)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0810">Translation regulation</keyword>
    <feature type="domain" description="Sigma 54 modulation/S30EA ribosomal protein C-terminal" evidence="2">
        <location>
            <begin position="226"/>
            <end position="278"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2440587.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="285" mass="31524" checksum="9209DDBDFE62E0A8" modified="2021-09-29" version="1">MALALHQQRMAQVACRQQASGRVSVRPVLQLASTRVSATCGPNLAAVAARPARSGLVVRAQSAKAAAGTVRIIIQGRKLPVTDAIKLYVEEKVAKSVANFAHTLKEVDVTLSARGGDTGTHGKKEQKVEVTIYTLRNGVVRVEDAENNLYAAIDLVCDKIRAKLQKIKEKAISRGTWPGRAGPKEDVDEEDFQEYLKEVKMDTQLFDKEEQLQRQFAELNRIYPANVMRSKTVVLDPITVEEAIDALEAVGHSFYVFREMTTDTVQIVYKRESGGYGVIVPQMRD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T899</accession>
    <name>A0A835T899_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Fatty acid desaturase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_010684</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000042">
        <property type="protein sequence ID" value="KAG2438887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T899"/>
    <dbReference type="OrthoDB" id="548508at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033885">
        <property type="entry name" value="AlkB/XylM"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38674">
        <property type="entry name" value="ALKANE 1-MONOOXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38674:SF1">
        <property type="entry name" value="ALKANE 1-MONOOXYGENASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0408">Iron</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0732">Signal</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="9">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032394070" description="Fatty acid desaturase domain-containing protein" evidence="9">
        <location>
            <begin position="27"/>
            <end position="526"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="258"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="282"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="49"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2438887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="526" mass="53375" checksum="AD7B11BB57EEF73D" modified="2021-09-29" version="1">MPAWARALLVGSGPLVLHLLVPLADMACGWWAGTAAAATGLGGASGRQQAATANAAPTAPPLGRAVRGIDAEDGAPPTQPPGPDNFWARALPMASILTHMAAVLYALTLVSAAATGGIPPPAAAAAAASAASPAAAVASTATTAAVPALLPLLAFTLAAAGAVAFGAIHELIHSRHPGHLTTMRAFLALFWWSPAAAVHHWHHKVMCTPKDHTCAPRGMTVYAFIPRYVVGSYAKAWALAAEACRRNRKPILSPHNSALVAWTAQLLSLAAISMLLGPTAAAFHAAVCAGMLVYIGALDYTFHYGLVRPPAAQLLQPLPPAGAAAAARDAELAADQATGATAAAAPSPQPPREYAPVTRFNSWSSSYPLENAMTCHGLQHAEHHISAGTSHAWLRATSARNPRLPAPLLLMALAGFVPPLWRAVMDPRADDANSQNLAHLRAAAKAAHATTAARCSPPTPIATPATGRAFAAAAGGSTSALGTDARAAAATGDGGEAASGMEVAGEAGEAERVTEAHVAWALQPAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TAN7</accession>
    <name>A0A835TAN7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_010150</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000037">
        <property type="protein sequence ID" value="KAG2440566.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TAN7"/>
    <dbReference type="OrthoDB" id="540198at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004016">
        <property type="term" value="F:adenylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004383">
        <property type="term" value="F:guanylate cyclase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000166">
        <property type="term" value="F:nucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001653">
        <property type="term" value="F:peptide receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007168">
        <property type="term" value="P:receptor guanylyl cyclase signaling pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd07302">
        <property type="entry name" value="CHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050401">
        <property type="entry name" value="Cyclic_nucleotide_synthase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920:SF335">
        <property type="entry name" value="GUANYLATE CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11920">
        <property type="entry name" value="GUANYLYL CYCLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00044">
        <property type="entry name" value="CYCc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0456">Lyase</keyword>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="89"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="371"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="10">
        <location>
            <begin position="188"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="9">
        <location>
            <begin position="428"/>
            <end position="644"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="919"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1050"/>
            <end position="1069"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="923"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="952"/>
            <end position="998"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="1050"/>
            <end position="1062"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2440566.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1069" mass="106902" checksum="94BC5C9C35EA4272" modified="2021-09-29" version="1">MTKRNAAPVKSPEPPADPPVMKPWQLRARNREAVTEWLWQDKSDFWAALGQAPKDPACLPPLTAHKGFFVAFRAQARAAWKMVCKFPSVLVLPLLVLTLLVGLGIFGVRTAADDHVKSSRVDAEAAALKAASAYSLSLDAAILPVLTMGTFIQETPALAALGPAFPRIAVDLLKQARNSAALQLKLVPFGIVRAIFPPLLDLGTLGLNLFTDPTRRQEALQTVELKSVWMAGPLEVPPHEQQVLIARNPIFLPVSSPEETWGNGVEGNTNCSECYDAETKTKFWGFAAVYIAFDNLTTGPNSPLLPLRNRNYLYRLTKPAAGENGQAVVLSESRPAPPGGSEAVAVPVYLPGIPWLLEVYPEGGYRPSWEAPLIVVVVVVAVVISLMMFVAMVNHRRLLVLLRARLPGKALDQLRLGRPFYDFFPAVTVLDCSVVRYYSAVGTPGEPWAPPSAGSSGTDPREIVKMLNDVYKSLDAIAERHGLHKVETYNDSYVCVGGCPEAGGKDAITWACHVAHCARDMVVAVAKYRSAGGQRMQLQIGLHSGACVRACVPGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGGWPGPVSAAVIDGGKRLPRYCIFGGTVTTAAELRATSQPQAIHVSRATAELLAEAGDPMVMLVPRGLIRIGSVAAAGGAAAPGGGGGGAAAAAGSAGGLMYTSWLQVDLMAGAYGGAYGARAPSTDLVSRHMDDDEVSLDGLNIVRKALRNSEDGDVEEEELDPEKAAAALGPLGFMHPFFGSFRRRVQPGDWEVVAAALGLPADGSGGEGAGGSAGGGATLTVGMVAAASTAAAAVAAGVAARAELPPAAVAARGQGQSEGEEADADEEAAVVAAEVQLGQQAEEVEGSCVAGGVAGVAAAAVKGAGGGASGSVVSSSDGSSSAGGLGRRRNSSMPVSPLTAPGSSSASDSAAAVTSGASDLPTAEPSGAAAPAAPESAAPVSTVPSLPAPAPATPTVSGFDERASVVSALNGYSLSMAIKGVEGLAAGATAAATAATAEVAPGAAAPAALRGDKPRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TAP3</accession>
    <name>A0A835TAP3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_010164</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000037">
        <property type="protein sequence ID" value="KAG2440581.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TAP3"/>
    <dbReference type="OrthoDB" id="509308at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="23"/>
            <end position="41"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2440581.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="155" mass="17256" checksum="267E4032532CF6B7" modified="2021-09-29" version="1">MVAIDPTVPSTSAIASQERSGPSIPIIALAVGVVGLAAMAFKKFRQNGLDDHTYRYSANMHLKDVMKDVNTVRIDDLTPEQIEAARARRSKERANHRLCLEDVELPQNHPFATKQKLTKEQQEAALNNLRARSMRRRNFDAMQEGAGGQGMGRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TB00</accession>
    <name>A0A835TB00_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="14">Mitochondrial carrier protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_011878</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 11">Belongs to the mitochondrial carrier (TC 2.A.29) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000052">
        <property type="protein sequence ID" value="KAG2435585.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TB00"/>
    <dbReference type="OrthoDB" id="1747031at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990542">
        <property type="term" value="P:mitochondrial transmembrane transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.50.40.10">
        <property type="entry name" value="Mitochondrial carrier domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023395">
        <property type="entry name" value="MCP_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018108">
        <property type="entry name" value="MCP_transmembrane"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045315">
        <property type="entry name" value="Mtm1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45760:SF2">
        <property type="entry name" value="FI19922P1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00153">
        <property type="entry name" value="Mito_carr"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103506">
        <property type="entry name" value="Mitochondrial carrier"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50920">
        <property type="entry name" value="SOLCAR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="6" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="4 10 11" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 11" id="KW-0813">Transport</keyword>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="90"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="202"/>
            <end position="330"/>
        </location>
    </feature>
    <feature type="repeat" description="Solcar" evidence="10">
        <location>
            <begin position="359"/>
            <end position="444"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006375"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000488"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2435585.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="14">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="445" mass="44553" checksum="37696543DDFA4D1C" modified="2021-09-29" version="1">MAGASEALRAPELHHRILAAAGASVVSALLVNPLDVVKTRLQASSVVVERPVPSCLLSRYPVRWARPSTLADCASSKLPAGAVSGCGSGVRPAAQGPGSAVGAPHRPLLATLPMSSCACAVKVADLGPGSLGSAEGCLSAAAPYRPPTATGVLRDILRKEGVAALWRGTDTAMLASIPMVGVYMPLYDHLLGRISSTAPPGLLPYAPVLAGSVARTLAVLLVGPLELVRTRQQGGAAGAGSATTAWGALRETLRDTTATATAGGAGAGAGASAATAATGSGATRPASSAAATAALLRGMPRLWTGVVATLGRDVPFSALYWGMLEPLRGALLQRWQEQQDGQGPAASGGGGGGASSGRAVLAANLIAGSTAGAIAAVVTTPFDVVKTRLQVGDVRQRQTGMQVMRQVLALEGPAGLFKGWGPRAARTAPACAVVVASYEVLKLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TC15</accession>
    <name>A0A835TC15_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="7">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_010330</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440448.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TC15"/>
    <dbReference type="OrthoDB" id="530204at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009744">
        <property type="term" value="P:response to sucrose"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004254">
        <property type="entry name" value="AdipoR/HlyIII-related"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03006">
        <property type="entry name" value="HlyIII"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="5" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="42"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="69"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="125"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="148"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="200"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="88"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR604254-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2440448.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="245" mass="26155" checksum="8ACB1E6289CAC39B" modified="2021-09-29" version="1">MTVSYSHGPPYKFRPQGAPAGAWPHTPWWLCTFYDPYERINVWSHGLPALAFIVLGALAKAGVVPGDNALAVFCFCAAMTHGSSALTHVWPDDHLLEKIDHLCIPFLIIGVPLTAVMALRPQGPYHVLTAVAVAAAGAAFLRPLHRTLAFIASGAVLFGYYFWIVDWNIVAQVVLQVAGGYFFVRNGGHSRPPGLQDHHFLHYCVTAASVLHVVYILKAVGALGGAAADGAAATMGAAVGRHKQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TC38</accession>
    <name>A0A835TC38_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_011646</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. BUD32 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
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        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="OrthoDB" id="3399at2759"/>
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        <property type="component" value="Unassembled WGS sequence"/>
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        <property type="term" value="C:cytosol"/>
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        <property type="project" value="TreeGrafter"/>
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        <property type="term" value="C:EKC/KEOPS complex"/>
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        <property type="term" value="C:nucleus"/>
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        <property type="term" value="F:ATP binding"/>
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        <property type="project" value="UniProtKB-KW"/>
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        <property type="term" value="F:protein serine/threonine kinase activity"/>
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        <property type="project" value="UniProtKB-EC"/>
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    <dbReference type="GO" id="GO:0070525">
        <property type="term" value="P:tRNA threonylcarbamoyladenosine metabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
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        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
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        <property type="entry name" value="Kinase-like_dom_sf"/>
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        <property type="entry name" value="EKC_KEOPS COMPLEX SUBUNIT TP53RK"/>
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        <property type="entry name" value="NON-SPECIFIC SERINE/THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="Protein kinase-like (PK-like)"/>
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    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0418">Kinase</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
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        <source>
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        <source>
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    <evidence type="ECO:0000256" key="7">
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        <source>
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    <evidence type="ECO:0000313" key="10">
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    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
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    </evidence>
    <sequence length="323" mass="31695" checksum="A60723EBA0EB6B04" modified="2021-09-29" version="1">MAGTVEAQGGDTSGAGGAKAANEEPQRITFLGRPALVVTLGTGGGAGAGARSHKRPRHDEAGDEGAQGGIRQVARSMLRAHKLGVLVPLVYHTDVESGRATVEDVAGRPLQALLDDMVAEAEAGSSSGKAAADLDAAAAALGRALALLHDGGQVHGGLGGGSVLLREGDGAVVLTDFRRSFNSIVALDKATDLAGLEAALLAAAKAKAGAQQQQQQQGEQVGEQEAAASAPGAAASAEGGGGSGAAAAPAAAATSKPAEIASAFFEKLLNSYRPSSRMWSAVHNKLAEVRARGTSQGGQGASAGAASAGTGSNKKAKTAAAKS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TCR8</accession>
    <name>A0A835TCR8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_010114</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000036">
        <property type="protein sequence ID" value="KAG2441272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
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        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
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        </source>
    </evidence>
    <sequence length="3651" mass="362737" checksum="475EFBAB15FF6564" modified="2021-09-29" version="1">MASEFGERGLDRQMRVKLFVKEDYEPPRTCEVEVPLGCDFKPLHDTVSDTILGGESERWTLLKETRTPRLGPDGAGHIEVAQEWQSKAAALFGHPGEDCAPVTSVGPDDLRGGADVYGVMLGQVAKTPLTSPQDVARWWASQPRSGPPLLAACCRRLLAKLRVAPDPAHVPPPAAARLVAEGLAGLRELATDRWYGARLPAELLDQGLLAALRWEKHAPAGKPALLADVLEAAAAATWALALYGGPRATLVSSGVVKELVVALAKAQAWRASALERGGGAADAAVAAQQDATAAAQEELDAAAAAAAKVEEEEAGKRSDGPDLEAAVAAADAAADAAMRQPLPDATAIALSTCYAPPAGEVSLSTANRLAYNCLGALGVLAVDSKARAAFLEADPKLSFLITAASTDFPCLAEVQHDLDVAAWLRRQTRRAAADGAAVERRRRRRDQRAERRRRAAEEARERAEREAEEAAAAAALEAELAREAEAMAAEDPELAALMASRNRSRTPTPPPPGQSPTPPPGPGDDDEHGQGEGGAGGEADAEAEEDELEPEPEAEPPAPDPYPLRDPVPTEEDPRIQQLMAAEALYAMLGRERGVRRAFAGAGGLAALQPLLLSPNDGVVVAAASALAAYARDAGHDHTSGVDMIATAAPPPPPPPPPEPAKTPSPAPGAGPRRSLAPAAAAAPPPPKRDPVIENAGKVAAALVATLPPVLEGMLVRYSAGAREVGGVVPGGPPAPPPPDVLEPLTVQPSRATTIGGRSVGGRSVRYAVSRMDSSTASTATGVTAAGGGAGAAYSPVGAASTRGGGAAAGFSPSPLARTVTIAPRHAESPVALSTMPSTRSQYNYLGTGSSIMGDDEDAAAAAAALATGLRGCFTSHKLSYVIEMTSTALWAAVSAELRAAEIKAAAVAAAKAAAEAEAAAAAAAAAAPPPPAPRLSSSSGMSESLLGNVGSPAPVPTLNLGGGAGGATRPSPTASPAPGAAPGGGGAVGPDADAGDATSLTPELLQHIAQLAVAAAKLVSTELIEMQAAVRGDGTSSGAATSTRHATQQSVTGRSVPGGVEGDAAADGGATAGSSSRSSHSHIMGSLHALLGCLCIVQGNNRLVRSEFKRLLARHATLRRLHTQKELAEEEMQALLDEMELARKQPGRFFFEEEEEAKRAEKQAKILQIEADMRKQLRAIAAAEDALQDSADSAVHAVEETLALLPYGNSLTGTAAPHSRQGTQAGEAEGEDSGPPPPPPMPHPLPPPLGAQLGHCHLLAAGVIQAMAATLQPGAVDAAFAAAAQLQRSWEAETSVSAAAEAADAADAAAAANGGDTLSAEALAAATAAAALYQGPYREAILGSGVMEKLLAAAAARYAAASAVQHGSYHASGGVPPSAAHLAAGGGGGGAGGPGSMTSRASRSPSITSSVSRRASGEGPGLPPPPPQPALVGATSEMRGGTATGGGGGGGGGAGGSPTRVRVMSAGTQQVDHATAILMQVTSCALMHLASTESALEPHQLAAALTFMRTAAHHAPCAPYIAAALYSLARHVPNRRGMVEGLEPPPGQRHISNGGVVGTGGGSGGTSRGAVADGKQRQGNVLGGAGPGSQSPAAGAGGAKRPPGAPPPPPPPPAVLGKEVWVEVLGSLLRSVLLRIRKHGQQPRTSVADTLGLGAMPPAAAGGAGSFTSANPFSTGAANAAAAVGPSAGAIPTPSAPLGHHSSSFAHTPTFTAGAALSGGAFAHGPGLAGPAGGATAGTGPSVSSLRSARFLVMASWLLLRQWLVDKINPVNLMTSADGVYARGGMSWWTVRFDADTPLELSGEVLEALGLVVEAAHAAAAAAASAAAAASAAAAAAAAADPLGHMTHFVSFNGDPGAVGAGRRHSWASAGFALPRPGSASRGGASNLPPGVAGAAALRRLATRCVWSLSSAHPAVAGALVDRGSGVLALAAMRDEGGAADSELQALCCGYLLSLANKTPNLLPPLGGLDALASALVALIERALAFGAAWPSQPHASSSGAQHPHQHHHPDHHPLVPPAAAHDVDGRGVDVHLLEAAVRGLAWLAGSGHEGRVAVTAARGVRRLVAVVRVDNAALAAVRERREADGMPDSVGLEELICPLRAINDLPITVPGAQAASLAALQPPLPPPSRPESRPRSPSVASRPGSAAPAGAFARSGSRGPGGAGAPGQLKPSASIAARQGAGAAAGSRPGTSSGPASRRSPSPALQPPASPAPPTPGPPGPPQLDEELLVASRQSGDADVGLMALWGLLNLSGHEPAQTRICRHGLYTLMSAVHGSADPARSAAARAILTNIHYHPGNATTLYKAELKLKYAALARLLQEEQAAKEAKEAALRRLAASAMPGLSGGKEAAAAAATAGSNGDGEAASFQRPQSAAANRPQSAMGRGAGRGSGRKSATAELAKQQLGVLAAAARAAADAASGGVAGGEGFGATLGSPAAALGGSGGSLPAVASPGAALGSAPSPTGKVNVRDSASGAVAMMATLSAALTHTDSGAITPRRSGGGPAAGVGTSMLQSPRGFVGGGGIGSLGGAGDSGDADGGGDDSLDPDAIAARLRFLQWMVDPTVKAGIEAMGPPSPLGGGGSLGEASWIAGGGGAVPSLGGDSDAATVAAAAMAAAGGDSGLMATLTSDPEEMAWLELMTRMQRNEAREEAKHAAGKFMRGVLTRSLAAGAHSLWREPGGEADAAVDGAVAGFAGGSPATGRNNARRLGSARPRPLSGASSGGGNRPRSASVGRARPASGLPVPQANGLKQSAPAPSLAWPPAARANAAAAGGTSARGQSPSAAGTGPAPSPRFASLHGIRNAPRPHGHAPQPHQPRRPSASGANGDVREARRGGSKTTVSAFSLSANPWAPHILRYVQEPMGGAAFAFGPGAGTTGRAELADRLLTATAPEYVTEDLAGLTERLMTLTSDRRKQEEEARRQKEIAEAQAAEEEARAEARRRLGLSPSGVYVPVGDMDMDDQDPFDFGMMGGVGGASGRFSLRVPALGLAAEGSQRSIATGPLSARGNGGTSFRMVTGSARPTPRLATMAAPEGSTAELSAAEAAAAAEAAAVAEAAYDDGGPVEPRVMALRVSLLPPALLGGVAPTGAMADGSGLDGAGGDVASLVGSAVAASAIIAGTLIPAPPSVIAGGGALTAVPPSYLGSGAGGGGAAGSVVAASLLTVSQAPSGLPPASAASLVSTTSVDAIGSVDPTLASALSNPADGYRKPHLGLAAPPGTRLSTLKPAKFTNSVLATVAVTSKGAAGGAGGIGFGGLGSPSGAATARSGLGAAAADGGFGVGGDSGDGGAAVSMAASRVAPGEGLAPIDGTVPRPVTVLAGSVADLLAAKQARELEAQNRILRANAIGGDDPFHEGPAGSAPSPSRRNSSPGGAGASARSPRSKTALSRAASRANGAANTGGASTGGAAAADGAAVGGIEPGAAAAGGGEDPALRLFKPQPVAVMVATGDGGTDRLYRFPRLLLPSAQHMCLFEHVDGCRFCEALYGHYLLPNGTLAHFYLGDTVVKGHRVDLTPAPAIPFSPADWVADAFPLCSALAEWGAVTPGRITHPTAASATAGAAAGATVAGGGELLAALWCPLPLTPAPLRPEERTALEWGETDDGGLELELRSVSLEVRLSVITRTETRLEIVAPPPAPTPKGRKRKPAAKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TD43</accession>
    <name>A0A835TD43_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009344</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TD43"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032509263" evidence="2">
        <location>
            <begin position="17"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="88"/>
            <end position="108"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2443272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="111" mass="10520" checksum="B6D6F9D009D51D5A" modified="2021-09-29" version="1">MGAALAVQFTLPALLAAPYIPAAAGSAGAAGPAVLTKLLPGWVLAGAGEQLAGASGAGRGNGLGLGLGAGGSRLGGFVSALKAPAMSWLWGVAAGALIEVILLARLPVPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TE59</accession>
    <name>A0A835TE59_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_011400</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000047">
        <property type="protein sequence ID" value="KAG2437145.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TE59"/>
    <dbReference type="OrthoDB" id="1891930at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48204">
        <property type="entry name" value="OS07G0265100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48204:SF1">
        <property type="entry name" value="OS07G0265100 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2437145.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="123" mass="12936" checksum="C7B74F90991AD84F" modified="2021-09-29" version="1">MAPRGQPQSPGHTAHGSADSIDHGAGPNTAGPPQHPATRGPAHPPSTSTQPAPTGVFVDAVTGRHASTSAADLLAKRRLTWDKHYGWTYDAWVDDPARYALAGANGREESRFLGWDWAGCVSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TEU5</accession>
    <name>A0A835TEU5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_009873</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000034">
        <property type="protein sequence ID" value="KAG2442083.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TEU5"/>
    <dbReference type="OrthoDB" id="3017231at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2442083.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="95" mass="10235" checksum="66A80F43FFEE7358" modified="2021-09-29" version="1">MSFLLHTGAPRHMYLSAEALKALEKAGLMVEDTDLDLDDTTLFGRKCPVEPTPAEHQPANIIGLKLLVRFGLQLHSEHPCVSCSADIPCLGAAVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TFX5</accession>
    <name>A0A835TFX5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_011320</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000047">
        <property type="protein sequence ID" value="KAG2437060.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TFX5"/>
    <dbReference type="OrthoDB" id="10256233at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00268">
        <property type="entry name" value="DEADc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011545">
        <property type="entry name" value="DEAD/DEAH_box_helicase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044742">
        <property type="entry name" value="DEAD/DEAH_RhlB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050547">
        <property type="entry name" value="DEAD_box_RNA_helicases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47963:SF3">
        <property type="entry name" value="DEAD-BOX ATP-DEPENDENT RNA HELICASE 47, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00270">
        <property type="entry name" value="DEAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="6">
        <location>
            <begin position="27"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="7">
        <location>
            <begin position="408"/>
            <end position="552"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="233"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="279"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="329"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="552"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="236"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="281"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="334"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="350"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="560"/>
            <end position="569"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2437060.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="590" mass="60804" checksum="027407A5BD2ECFAC" modified="2021-09-29" version="1">MLKTSIYKAQLAARGLQQPLPVQAAAVPLILSGHDVAIKSCTGSGKTLAYVLPIVQLALQRRVAAEAAAAEAAATASATAAATAEGQPTAAAAVAAARARATALKQAARGVQAVIVAPSRELCIQIQRAAQELLPPSSPRQLVQQVIGGANPKRQAAALSGGEAGVWPAVVVGSPGRLAALVGAGPRGGLAVWGCPMLVLDEVDTLLAHDDFCRHVDLIASHVGRRVAASTLDRCSSSSGSSSSSSSIDSSSSNGGFGGGRQTVLVSASLDPQRLEAYSRWRTQPAATDSATFNEGGERRHSYRRQLELVALDSRAALPEQYLRRQLLKAQGVDNGSTSSTTDAGPGTMSVPSANSASSVPGSTSSGSPANSNSTTSGSNTSPRLADVLPPHLAHVYVLSPPEHRTDRARRLIHALGAERALLFVGRGNQAAVTKYKLEARNMQVSLLTGQLSRLERSNIVAAFHAGTFRALVATDLAARGLDLPDCDAVINLGLPADALAYAHRAGRAGRAGAPGVVASVVSRSELKALEAVAARLGVVLQAISVAHGSIAPQDQDDGQASRREDSLKRTRGAPAKHKQSEELLTGCLE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TFZ8</accession>
    <name>A0A835TFZ8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Protein phosphatase</fullName>
            <ecNumber evidence="1">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011212</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6 7">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29035"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the PP2C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000046">
        <property type="protein sequence ID" value="KAG2437571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TFZ8"/>
    <dbReference type="OrthoDB" id="60843at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039123">
        <property type="entry name" value="PPTC7"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320">
        <property type="entry name" value="PROTEIN PHOSPHATASE 2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12320:SF1">
        <property type="entry name" value="PROTEIN PHOSPHATASE PTC7 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07228">
        <property type="entry name" value="SpoIIE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00331">
        <property type="entry name" value="PP2C_SIG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0460">Magnesium</keyword>
    <keyword evidence="1" id="KW-0464">Manganese</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="1" id="KW-0904">Protein phosphatase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="121"/>
            <end position="361"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU366020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2437571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="367" mass="38358" checksum="2864208046A16ECF" modified="2021-09-29" version="1">MFYRTATASQQAAASGRQSSVLHRLAPQLLAARPSVSQHHHLNPAAPAQWSSANRSAALLGLTRAGSLLAMSCLADEAMAASYTEEPAVAASSFAAASAVATQLPAEGNGKPASTGGLLLTSGAFVLPHPDKVAKGGEDWYFIAANHRAVGVADGVGGWSEVGVDAGAYARQLMGNAANVADEVTATVPDAQEILERAYNLTTVRGSSTACVAVLNGDNLVVSNLGDSGLLILRAGKVTFHTPQQQHGFNFPYQIGSADSMSDSPSSAQRFEVAVQPGDLLVLGTDGLWDNCFDEEVASVLKYCGEQKMEVAKMAQVLAHYARHRASDSKFASPFAYAAFQAGYAYMGGKMDDITVVICHVQQPAKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TKC9</accession>
    <name>A0A835TKC9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_009618</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000033">
        <property type="protein sequence ID" value="KAG2442129.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TKC9"/>
    <dbReference type="OrthoDB" id="549783at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="413"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="415"/>
            <end position="426"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="444"/>
            <end position="454"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2442129.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="573" mass="58407" checksum="DCA20974C114CF57" modified="2021-09-29" version="1">MAGVPQRRPGPRPQAVSCSGAGGAHGSSSGCSGARKDRSDGTVGVAGGGDTSDESEGGIQTDPTAHAAALCRVLGLPAPRLMALVGRCPDLFAFSPAALEATLEAVAALTGLQRVVVPQLVAADPGLLLAPDRLKGNMRELGQVLQVPPTEVVNMAAREPAVLALGGAEAAARLEALAAALLLAGRPALPLRHSQLVEAVLAAPGALLAPPPEAIQAQLEALEAALAPLLPTEELEEVTAQLEPASASAAAAASAAAEAAPLSASPSPSPTAPPASTSSVDGPLPAASPAPSSSSSSSSPPSPWPPAATAAHEHQPPQPHQPPQSQQPQPPQKQHHVLPLRALTAPLVLAKPSLLATPPELVAGRVAHLAAKARISAAQVLLAAPAGPNLLAASSCHIDRHCAAMAASLGTALRFPPPPPPPPSPQAPASATTVDSGHARRQPQRQQQHSGQQRRQLREVEAARAYAADPEAAAAAALVAEPRLLAQHVNAVAAKWQLLAAIGSTSAVWAARLKAATVAERAELLVLPYTHVARLRFLADRDMQDAVDLVAAVRLSDALFHFQFPGFREWLRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TMC2</accession>
    <name>A0A835TMC2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_009971</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000035">
        <property type="protein sequence ID" value="KAG2441381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TMC2"/>
    <dbReference type="OrthoDB" id="10672914at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="76"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="278"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="666"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="872"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="931"/>
            <end position="978"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1047"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="43"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="154"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="282"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="699"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="936"/>
            <end position="946"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2441381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1047" mass="101219" checksum="179A6E841F35C7A1" modified="2021-09-29" version="1">MPLRLPKQAGPSAGGHASPHRASNTGRTSPHPAGSVSPTRRRQSLDVKRGDALKIEKGARRSLDVSDSGYARKAAAVVGRSSPTLEPLPPAAGQPGGGAKGTAATQGEAGAATPFVAAATGAAAESKDAAGAKSGAARFGRRLLNLFGGGKGTGSTATATHAAPQQQQKPRPPQPHVSEGYAVASEQDGAAVANTDAAQLLCTRSGSGHTQWTAGRDGTAAATDMSGSQLAHTLTTDTSLSTSQHFDKLYSSELSGCSPTPGSASVAAATAVAGHADHRPLASAASPDAATDAAANPSRGARRPESMAAGTNQRKANAPLLAPGKGLSASATAPTACGLPRSGSFTPTASVSFGPAMLTAATGAAGDAWPVQESPSLAEVLASASAEAQLPLRGGGRGGRQRRSSLDFTPALPAHLRASLDSSGLPSLTALGAAQEVARMRSSLATVSAAAGGAQNPGGAGRLRPSLELFGGTAPSAMTRGETRGSGGGGGQSRTLNPCLAAPMQPALQRAPGLQSGMPAQGGPGGGWGGGSCSTGQLLLVGTDMDAPAGAEALRVAAGGGASRELHLAAGGVGARYGGGGGGGIAGGAGRYQASAQPAAATTWAAAEAAAASSVSAPLPTLHGGLWGASATVSTMPMAAVAAAAGVQHPTGAPAAAGPPVGGWRVARAPVSSGDAPLPRIGTAGAPAMQQQQQQQQQLHHHHQHHHHHHHGFHLNLTGSELPALRGGHMAAATSAPGEAPPSPHCAATAAAGATAAGAAAAGDLVRRSREFGLAARKATAPIRSGPGGSGSLVVTGNSSVGCGSGGHNTMTLHPTADALLATMQTLHSPLLCQPNLAACSSSTHNLPQSPGRFASCPATHGAITTAAAVASTAGGGSSTRNPITTGTGGTASATPAAASAPKPGAEAAVTAATEAAVAVSACTLAWATGSVSSGPSGGGGGGGGMPTERGGRGPLDSEVGEPSPARWAPHVPAPATLHPLQPEPITGIAGRAALAPSAPGFGLAAVRRDVLAGQNGRGSRCGERGGGDGFVGGRGALADTGASDDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TNH7</accession>
    <name>A0A835TNH7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GrpE protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_009679</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000033">
        <property type="protein sequence ID" value="KAG2442191.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TNH7"/>
    <dbReference type="OrthoDB" id="201635at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.22.10:FF:000001">
        <property type="entry name" value="Protein GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010741">
        <property type="entry name" value="PRK14143.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF40">
        <property type="entry name" value="CELL CYCLE AND APOPTOSIS REGULATOR PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="31"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2442191.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="223" mass="24233" checksum="F673A91A5088909E" modified="2021-09-29" version="1">MKAAEVQEAEAAAAPAEAVPATPLERVKHALESETLDKDVLTAALAELEAEMGRLQSAASEAGDRAKSLEASVASAKDQYLRLNADFDNFRRRTREESAALTDSVRGDVIKEMLPIVDNFELARTQVKAETEAEQKINNSYQGLYKQMVDLMRSLGVEAVPTTGTPFDPNIHDAIMREPSNSHPDGTVLQEFRKGFAIGGKLIRPAMVKVSYTEEGPAASSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VX50</accession>
    <name>A0A835VX50_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_014156</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000088">
        <property type="protein sequence ID" value="KAG2429118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VX50"/>
    <dbReference type="OrthoDB" id="547452at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="26"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="431"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="521"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="623"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="908"/>
            <end position="972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1101"/>
            <end position="1137"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="759"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="825"/>
            <end position="873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="457"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="529"/>
            <end position="538"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="553"/>
            <end position="566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="635"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="659"/>
            <end position="681"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="919"/>
            <end position="943"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="948"/>
            <end position="958"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2429118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1137" mass="110196" checksum="C445D2481400547F" modified="2021-09-29" version="1">MATNSGGFRQAYGAYNDEEYMFDDDMDYVPPARKKPAFGGKERPTNKRPTPAHSPPPGAGGLATSPKAVRSRPTNNQLLYKAYFRWAHYPHKLKNANMPVETDACASVTAAFLQVLQIMQTAEQLRQGGNKRNVLQILSSNTRRTKVVELSSGTHRVPDELKKHYLSDGEGGQYSTNLDRNRYGNDDNYLFTVIRYDLEFLGLCPCMVDVEIIDAKQGNSSIIVSAGTEVCTCQGGPPLGGAAVGGAVGTLGSSGVGGTVHPGHMAAAAAAAMGHLGGPPAQTFSGGDRHGMAMKPEYHAPDAAAAMGALAAGPNGAYAAAAGMGLAGLPGLGVGGLPGLPGVAGVPPGVPGVPGVPGVPGVPGLSPADMAAVAGGAGPPLFGPGGFRGPAAAVLGGGPVGRESPKRSGTSVSQLFDALVMAATGGADGAAAAGGLGGEPPVTSPAHVDQPRTTAGGMAGGAGAAGAPGGGATQRLHPPPNRNKSKLWSLNNLSYGGEVDSLQNALDAFREQDEIASGDPAAFLASGLGPDGSTGGGLQRSDSLRQRRRKPVRNSSILGRPASSSGMAPLTGSKLMGGAMSLREKSDDNLKLAAADPDLGAALGAMNAGAHPAGILPGTSFQVSSLASGEDDNDGGGGDQADGGTGGDEALAAAKGEDLGVEGEGEAGGEGGEEGMGEGAEEVGAGRGGAGAGPTASGTLRAGALGARSPLRHHVRHVPRQSSVANLAPRVAGAGAAGGAGAGALSLLGPGGLGGSAQAAIAGEQLKRLANELEVMRAENRSLRQQLQRSNSSTGAQLNAAAAAGGAGATAAAAANGSPSLAKTDNSESQRLRKLESELASLRGELHGLSDAKKSAEDEATRLRRDLLASQQQVAALLSKVLGGGVAGGGTDGVSTQLAAQLAATMKQAAGGGGGGSGPEAVAAAPAAGGSSGATAKAGSSAPAGGGESRKRSAEEAGVRAADGSGSEEGGVALKKPAVESSGGGVTGGSSSGGAALDSLPSLCPAAGLGAAVSPAPGQAVGVGAGAGGAGGGAAQPADSVGLTMVTTRADSMCFSDLQLLERLPTLDGIDFFAPASAAAATVAAAGITAASSRGASAAPTAGGAGGCSASGSASLPQVPARLSGTLGTGQPAGPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VYU2</accession>
    <name>A0A835VYU2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_012357</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000058">
        <property type="protein sequence ID" value="KAG2434337.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="545881at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050697">
        <property type="entry name" value="Adenylyl/Guanylyl_Cyclase_3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="654"/>
            <end position="679"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="3">
        <location>
            <begin position="2327"/>
            <end position="2366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="796"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="936"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1311"/>
            <end position="1341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1436"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1472"/>
            <end position="1491"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1496"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1650"/>
            <end position="1676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1698"/>
            <end position="1778"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1813"/>
            <end position="1862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2124"/>
            <end position="2146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="848"/>
            <end position="860"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="936"/>
            <end position="953"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="980"/>
            <end position="999"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1004"/>
            <end position="1024"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1041"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1275"/>
            <end position="1286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1448"/>
            <end position="1458"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1499"/>
            <end position="1509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1517"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1752"/>
            <end position="1761"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1762"/>
            <end position="1778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1833"/>
            <end position="1842"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2434337.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2427" mass="242947" checksum="D22F70841BF66092" modified="2021-09-29" version="1">MAVTRPPAWSAEANTVTSAEHLVVVCGLHPSQPTLRTLAADHSRRALVPGADERLAVVDVLVEKSKANVTVNARAVGRAEAAVEVLLRAHAAGNTSWLRQLNASAAAGAELPAEVLTPRLGSADGPAAAPLLLLYRRDWWQRLVEIWGLGGNSGDDSGSGGGSGNTTFAEQLLPPTWDLLVRLLGVLRNSDLDGNGSADHVLCADLQPGCKGWAVLAAVYASVAQTQGTQQGMWFNATDLRPAVGGPAMQAALQTYAALAASNAAPFTPGGAAVSLSNVSVSPDDLLQGGGGSGSSGGGPACGAVNPLFAAGRCLFTIDWATAALRLTQNDAQGMNMTGHVGAAPLPGSTLVANRSASSATQLQPCTPLSCPNASASDSAQLAAAEQLLLRLQAAAKDVPPTAAPTQQPAPPPQGPQPQLQPPLLLVNRAPLLGEASPAWAVEPRQAAASYLRTDDFVRLVDFELGLKGAALLAAARARAAGAGSGTGNSSSAIGAGTMVSSLAGATATAAALVAMSAPEAAQLLDLHPADLAAVAQAVGASLDHPNAAVDISLPYSAEYRAVLDDLAASMLQLVANTTAVGNGSAAPEDQVAVLTASASVRVVAVGTAFPYPAILLRLYWQATGFTPPSQAGDGGTNSSEGNVASTQSAALRIGLPVAVAVGGALALALLGVVCYAFVARRRASERALFRAMKPPGAGPTTTLVMTDVQNSTLLWEVLDVHVMDECLSLHHHVMREAIAANRGYEVFTEGDAFCVVFYSPDSALGFALHVQEHLLTQPWPEELLQQPDGCEVWARRCAPQPPPQSSLTREQAGAGAGMVGPGALPVLLEGAVEGPSTDGTNTPTRGLTGGGANSDGGSWGANQPSRLRPARGPSPLRQATSASGLRSGRDPEPAPAVSAAPKPAALLAVLLDTSGPLQGSPTEGAAAAASLLPAEAAAGPTAQQDPQPAPQQGGQGGGAGVDDGAHEAVVALRPGALLVEEDEDDSDKDGEAGGEEEVERPSNRSSRPSAPSRALRPVPRPSATGLLAPAPPEGELILPVRPPPPLEDGPFPAPPPHPRPSGSGTAGGARPPRSSRRMLPAAACLSDNGFSPQPPPAQPQPAALAAAPALLVAPMKPELPELRQERSLPLAQGQDAAALADAAAEVAGDEAAAAATAAATVLVTSRRPSQNGKAGGAQAAPITAPAGRGTGGGSLANGGLVTASQLPRALPPPMSATGGRPVSGSNLPRPNVLPGGGPQALPRQQQQQQHVSGKLALMAGGSSQAGSGKLPIGEAEDEDDDEDDATRDWRKHINWNAEDATPPPLVSSLGSAFGPGYEQLAAPDGASATLPEPTAAHSPRAQAQQQHAAAAWQVAALMGGERHADGNGSGATLRATFDGSTGSWAPVSAHAAAPGDAGALALGVGAAHTKPLGTATLGRFRASLPRLFQTNASLPARPQLDLSNGGASVGGAGTGGGEAGTALRQAANVYGSSSGGGARAPSGPLKTRPLPMLHLATSMPAPGSALPMPGAPPPSRAASRTPASALAAVGAGHSSGASHALSSTAGRRGTVHRLSMALYRTNAASNAYSNVYSNAYSNCAATSNAAPFISPSATGRYGLNPSASMAAYGHGYGPDMYGAGAAAGTSPFMYGYGSSNHHLPLMGPAYATSPPASVTSEAPMGTPRLASGAGPRRGSLPRFVASLANSLRRSKATLLGGGGAGSSLAGAVPSESSLACPSTSPPSGVPLGPHPLHGNSGQPRRSHGDDPSARQDPSNHQLSRASSAAGPAPAHTSPSTATAGAAAAAAVSSSGQLPSSGLLMVAVAPLYVGPDDPAADADAPTSPAEVELGGMQQQQQQQQQQPTAAGGGGLRPGRASLMGGGSVTSPLDALWRDLNSVNSLCRQTDIGDGSGAGGGSGVAAWLASAGCTIGGVLCSMFTTVPPDQVTPRLRTRLTQEAGAAPAAGEPRLSSSALLAKLGGRSVVGGGGATAAAASAGSALMAAVNGLPSPGGDRDRGSGGTFSGYAGFGLGAAGGGGVGGAGAAGGEPVPVLAFRGLRVRVGLHSGVRVNEVVSLGKEAAGAAADYKGDVVQICKEVSDVAMGGMVVLSGSAFRALQLLAGGRGKSRAPEAMLLHLGEHVIKPPQAAEDRPSRSAGTGGQPDAPPPTRELYAAVFPSLACRLALLPSPVRTHSELVPGCLSAPAGLVAPVFCNVVGVEALLAWEALVQERLMRAAAVASAANLAACRPLVGGEAVAPLDTAVGGLGMVREALDLFGDMAQEAASRHGGYVVASSADGGHWVLVFGCAEAAVGWGLDMLQAMLTAEWPDGFLEHELTEEAWEGGVLVERGLRLRIGVDFGRAMVRLVPRSGRLDYVGRPMNRAARIAAKAKAASVLMSGAAWSAARPALGSSVAATNLGTMQLKGVKEQLELWEVRAVRTGDAEHYME</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W1C0</accession>
    <name>A0A835W1C0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">t-SNARE coiled-coil homology domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_012690</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Endomembrane system</location>
            <topology evidence="8">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000062">
        <property type="protein sequence ID" value="KAG2433573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W1C0"/>
    <dbReference type="OrthoDB" id="261831at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd15853">
        <property type="entry name" value="SNARE_Bet1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.110">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039899">
        <property type="entry name" value="BET1_SNARE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000727">
        <property type="entry name" value="T_SNARE_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12791">
        <property type="entry name" value="GOLGI SNARE BET1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58038">
        <property type="entry name" value="SNARE fusion complex"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50192">
        <property type="entry name" value="T_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0653">Protein transport</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="89"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="domain" description="T-SNARE coiled-coil homology" evidence="11">
        <location>
            <begin position="18"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004394"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00046280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2433573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="109" mass="12341" checksum="6CA50D503A5C9EB7" modified="2021-09-29" version="1">MLGTRDRRGLSRDKVDIESMEQENDRELDHLADRVALLKNVTHGINKEVNDQHRLLDNMDGSFASVGGLMSAVTDKFRAVYNDKANKRLIYGAVGVAAGLFLVWYFMLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W1D9</accession>
    <name>A0A835W1D9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HYH02_012588</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000062">
        <property type="protein sequence ID" value="KAG2433469.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552831at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005216">
        <property type="term" value="F:monoatomic ion channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0098703">
        <property type="term" value="P:calcium ion import across plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024862">
        <property type="entry name" value="TRPV"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582:SF2">
        <property type="entry name" value="INACTIVE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10582">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL ION CHANNEL PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="12" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-0106">Calcium</keyword>
    <keyword evidence="4" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="3" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="13" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="11" id="KW-0407">Ion channel</keyword>
    <keyword evidence="9" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10 15" id="KW-0472">Membrane</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0677">Repeat</keyword>
    <keyword evidence="5 15" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="8 15" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="2145"/>
            <end position="2168"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="2429"/>
            <end position="2446"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="2467"/>
            <end position="2487"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="15">
        <location>
            <begin position="2540"/>
            <end position="2564"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="12">
        <location>
            <begin position="571"/>
            <end position="596"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="16">
        <location>
            <begin position="2382"/>
            <end position="2571"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="77"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="171"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="485"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="814"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1051"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="1593"/>
            <end position="1615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2020"/>
            <end position="2058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2181"/>
            <end position="2212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2306"/>
            <end position="2333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2669"/>
            <end position="2709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="2730"/>
            <end position="2757"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="13">
        <location>
            <begin position="2783"/>
            <end position="2817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="95"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="247"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="14">
        <location>
            <begin position="492"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="512"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="814"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="828"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="2044"/>
            <end position="2058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="14">
        <location>
            <begin position="2306"/>
            <end position="2319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="14">
        <location>
            <begin position="2736"/>
            <end position="2748"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG2433469.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2821" mass="291658" checksum="5EA873B732C61E08" modified="2021-09-29" version="1">MTQGRASGVGELQQNPLQALALLERALSTSPDEHKRALRSVLDYVRDCGRTRSTGAGSDGATPAALQWADPPLILGPSTFDSGLSPDDFPAHPRCTSNGRSVSATEAGQRETPLQAADSHGGNRHTPSGLRGLQKLLLSFKPSKQQDQDQEHQQQQAGGDEIADAAAVVAAGASRPGPSPSSTSSPSPTGPGTHGVAPPPDSSLPLATAREGPQQLQKAARRSRLPPHAEYPAGQLLHPAGGDGALSQRTADSRQPQLEVALSIASAHSGADTMQCQTGQQQLPSSGSRAAFGKRRLKGMLHVPFRCAGPDMGAEPPMAGPTSAGGNPSLTLVRSGLFSASMMHMLGLMFGSRPPTCSAGNRARGASGRSYMRQEAQVSLVEAEQAAAAASDYQQWRGQTGLRLLLSGGYLLHACTPLSAAVSVAACMRSSAAAGGGAAGGCPAGCGAAASSVDVPQAVGGSELVELVRQWCISADLVNWTPSVSPTWPSPQASHQVPQQQTAPAEVAAPSGGSGCTGPGGPAATEGAAAAGAAIGPEHVQLQGLGDLKPQAAVAAADTAGASAGADCWVSPLAAAALHGDVELVRLLLEKGADPNGRCWLPDGTVFTPLMVARIWEVARELLVAQGVEERLPEPLLLTALQLSTQLPPPGGLTQHGVGVGSDGSGEIGVQGPTAVGADGGRECPQGQEQLQRERTVQLLLEVVKQAAVDGDAEWERRRQQPQSCAECLARVDPMLGPGIDPRLAVLWLKLGGPRAADKPVFRHPERLLPPAAAAVGSRHCNSDGSVFWLAAPDDARLMHNKVVRQGAEALEAAATAAGAKQQQPQQDMPPPPPPPLTLGEAAMLSRIAVDAAAHRDRHWPSAQLEVLTVGSPRHPTTPAAAAAASSIASFATAAGAVAVSPGGCVAGPRRQQQLPTPFMQQQPAADSISRSGAAYRAAAGAHSPTAAAARQPPATPTSMLTFTSDMLSSSVSSSSQALVPKVEHAGSSTFKGCADVGCKQADKPPRDWCMRYAALCDIPLLSLELLHHAVAGGSSSCGAAVARSAVSEASPALHVPPPPPPTLLALLAGQQQRQHSTPRDRRGAGSAPQQPQREALQRLHSTPAGALAAAAAGGRLSPAVLMQTPSMEAAPPAAAGLSHELPSPAAADVAGPSMTSAFARQSRATPSSHVSYSGCATGPAAAAHMVVPFAVPSAPTTDLGSASQALLSVAAEWWVAKSFGCEPPPGRGEAAAVQQKKQGAAAARRWWLPRSAASRRQGASDAATHGSDLRTADATGEVGVLVELARKYERPGSLFPSLVSAYALLYWLWTPAGESQPPLVAQSMPRQLMPPLPEGAEPFASQPAAVESMSYWPSPMAAAPQQGPEVSGRSVTGSLLGYHAASMPAGVGGGPAIGQVSHRTAVGLLSDEARLQQQMVLTLLQHAEGVMGDAAVAYCRLLAFHAGKTLGRRQDQQPVRAPPQRAPNLRVGLSEWVSGSQAAGSAAADRSTGKAAGVHAAHLLQSQQASPLHQSRPTTAASPHCASKGGLIKFLCKGALCWVHGQARAMLGPATPGIACAVAAADGGGSGQQRQAREMLNVAVVLIGAAQAHEATAGGMAPPTPNAGAGAGGTTAGAAASLPSTQAQQLLVKLTQKARSSKPAAGGGAAAGALPPANPEYEAALFRAAVCCSRGSKQCNTKFIQAAVSGLQAVAQVAAAEAVQQAAAAGQAAACSGVSPAPPANEFAPGLWADAAAKRMLLLASGLSPGDADGVPRAPGPASEVMETWVAGLRAMSQRDWCQDGGYAKEVDHWLTAAGDNAGGLHNLHPDFLALICRVALSIDSNGMLLRRGIKALAWQLRREPLAPTHQLQMLLEELLDESPRQVARLLAQTGLGWASAVQPTASAAPEAGGGAGSGAVSGPPAAAVVVRSWHSIMVETALGRPPAALLEDSAESSHGYIPIAIRLPPAAGAAPAAEAACPHNMVAAGLWDWLSGWMRRQDMHMSHPVLPADAMSPATSGRIRKSISVVPPLTEMLSGALAPHNSTNAAGDDAAPDAGGGGGGAAAQSRSSGANSSSGSSSLVRLSAMLLEDGGDGTQQLDMLARRDSLVSLWWDFARTPSALNDKSVREHLWRPDMGGAVPHTFTSAFMAALAVLCQGCVGVGGLFGLLYLTSCALLTTILALMGAFVKLRFGWRPTGAGSRAAGSQQHHAKPGAAGEAAGTGATGGRRRTSQRHGQYYSVAARALLLPGVTSTLLEQRQHLFSAMLSDQRIPLETWGMPGIAALVLHHWQSFTAHVVLQMFLQRAVYTIVFSMYALSLTGTEPPESPSAPPLAAPPPVGMGGAASGMQSSRQDSGLAGALGWGGGVWSYNEGPVCTGWPSRLHIKYIAVLMYMSLEYLVVEVRQMRMGFYDWFRQPWNLFDAVQQVLMFTSLSLHLSCTASVEVLQGLDQVLVLVLFWRLLYFATGKRGMGSFVRMVMLVSYDLRLFFIFLAVVYVGFGVAIMVVAPDWIPNCDQGGDCNMDVGRGQMVFLRLYSMIYGDFDATLLLRPGVASSGLAKLTSLVAALYMLFVSIILLNLLIAIVGDAYERVLESEGATDIRNKANMIVEVEQLMPGWLRKWRDRVLLRCDALLVLQNEDAMSVPSGEVAAREAAVLGQTTQQALQRPKMEHANSFTHLLFRSVDGGFSPTTPAGPGGIRGALTSSGAVDTGARTGRPPLAAARPSEGGGALASGLEAAAGAAAASAAATAAPGAEADTDPLVDREEEPPLGGPWCGRHGTTMNALRTLQHEMQRQGAQQERRAAALLQLVQRQQQQMEEQQTLIQQQQARLQEILQRLPQG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W3H3</accession>
    <name>A0A835W3H3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FMP27 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012240</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000056">
        <property type="protein sequence ID" value="KAG2434576.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552990at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045167">
        <property type="entry name" value="Hobbit"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678">
        <property type="entry name" value="ANTIGEN MLAA-22-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15678:SF6">
        <property type="entry name" value="BRIDGE-LIKE LIPID TRANSFER PROTEIN FAMILY MEMBER 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10344">
        <property type="entry name" value="Hobbit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="44"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="108"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="161"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="282"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="347"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="633"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="766"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="924"/>
            <end position="944"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1173"/>
            <end position="1207"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1269"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1406"/>
            <end position="1439"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="44"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="633"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="767"/>
            <end position="787"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="928"/>
            <end position="942"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1184"/>
            <end position="1194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1274"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1291"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1341"/>
            <end position="1365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1406"/>
            <end position="1420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2434576.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1714" mass="167235" checksum="811651E412B07B4C" modified="2021-09-29" version="1">MTYASRTLVRSNGTVLVKPTSRPAMTALSVEAFDIRLLLPPSPPSGPAAAPLPPHGPHAPSAGPKHGRSSSGSGLVDGGGLSTRGFGAGLIAACDCLLLKQGSPDPADVPGVAGGPGGGSQAPAAPPSRPIRIIVQDVQVLCTSDTRDAVISTTAHIMEAFTRSSPPPAARQPAAGATEGAGGKGGGTGEAGSGKRPAGAAGGAVSGQLAGPAGGGREGAAAAAAAGALAGSSGLGPARLVSSALTHSGEAELLAEAVVAPRVYAAEQSLVALLRQQNEARRAEARKRHLHRPSTSTASGATGGSGNGGSDDEDEAAAVAVAVLDPALDPAEVMQLAGEPEELGLARGAGAAGGAGGGREQEAAEGPGAAAPAAADLPGGGGGREMVTTYEVEFVRVQVGLIADPGAGPGPGAGWGSCVVLGADSALLRGQRTSPGALAAGAPGCKRLTFEVETLQAYAARVEPSARDVSVAGGAGAGAAKQQSFSPLSDNLVAAVGGGGPSAAAAAGGAVPAAAALPAGRSVAGGLLTGAAAARESLEAAGAGGELGGPAAAVGGPVTWLRVVNGTLVPPGSLSAGPEAPVAVTARAGGSGVVAMEKILNPFRFHLTSARPWVVTAPAPAPVAAAAAQPGGQVAPQAPAAPAAPAAAAGPGGRTASASGGGTQQQQQQQQGQLSRTGVELDIDVPSISGQMESWQFQLLLAVINESVAAPLPRVSLLTRGAGARTSVDVDSSPEVIATLDTIISLRHQLRCLQHEAVELSNYLVGHSHSPTPQQLQQQQQHGGQQQPHHHHHHSPTRPGELLGGPYTASLFKPVALAAGGGGGSGMEVGDRFTWGGGGGGMQPRAAATSLGAVPPVVLAQNLLAPRPDNLSPALLAALRRRNQELLLHWAWEQVSGAQESLEATATALMRLRLEVAAALEDQMGAQPGSGGGQGAGGGGARGGRRQAMTVAVRLGRFSWALIGGSGRDKAPFVQAELRGMSFNHSLDRNYTGTTKIQMHAAEMRELGAAAAGAAAGPGQGQGQGQGLAAAAAGAGDAAGLPAAGSLHGQPSVAGIGTVGSAGAGGGGGADSGRASAGAAGATAAIAAAGSAGAASVTSTASSAAGGGGSTILSLWRPDASRSWDEEPLLRMYVVHGGADGQFVTYEHIEVYLHPLQVRLTYALAHSLADYFNLKDDDDQPGPGRDRDRDREEDGGGGAARAKRDKVKAKAGADAAAGAAAAAGAAGAAGPTASPAKAARAGTGWFGRRATVAASAGSAAATAAPAAQRAVTEAGGGPGQGWEGPGGGGVSASAAVTGSSPRKTAAGAEPDRPSLQAGGLLLPLYAQTAALQQLQQQEAAGTALRGKGPDAGAAAAGVPSRRAAAAPPPPPPVLVRYGPAFRERPDGRVTILVDLAGVLVPGTAAAAAPTSTATSTAPSSRRGGQASGGDTDAGSGLPSRPPRRLRFCYVRFNRMAACVTYVGPRLRVGGGKNGGLGLVIDSRTYRNIEGGWRDILAKYKWDIIRSIIKSVTGIQSSKLKELRGTGGGAAAAAMAGAGAAGGGAGGGDESELLGYAALAAMGLDDLDIAYTPDGPPPGAPALGAAGPAGTALGSLAAEAKRRVTAAMAAGAATGARIKQAVGRSVGSVSAAAEPNGGGGGAELLQGDERQQAAAAAAGGGDDDGSLLPLGAEAADLVRQSSSRVDYDRLVRAGAAARARATRLAALLGEVPRKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W4I0</accession>
    <name>A0A835W4I0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_011440</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000048">
        <property type="protein sequence ID" value="KAG2437008.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W4I0"/>
    <dbReference type="OrthoDB" id="10264544at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046540">
        <property type="term" value="C:U4/U6 x U5 tri-snRNP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd24162">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013881">
        <property type="entry name" value="Pre-mRNA_splic_Prp3_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027104">
        <property type="entry name" value="Prp3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010541">
        <property type="entry name" value="Prp3_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212">
        <property type="entry name" value="U4/U6-ASSOCIATED RNA SPLICING FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14212:SF0">
        <property type="entry name" value="U4_U6 SMALL NUCLEAR RIBONUCLEOPROTEIN PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08572">
        <property type="entry name" value="PRP3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06544">
        <property type="entry name" value="Prp3_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pre-mRNA-splicing factor 3" evidence="7">
        <location>
            <begin position="249"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Small nuclear ribonucleoprotein Prp3 C-terminal" evidence="6">
        <location>
            <begin position="615"/>
            <end position="752"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="211"/>
            <end position="253"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="284"/>
            <end position="320"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="387"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="677"/>
            <end position="705"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="7"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="25"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="294"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="389"/>
            <end position="404"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="693"/>
            <end position="704"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF06544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF08572"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2437008.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="765" mass="78351" checksum="AB1C9A271555FD49" modified="2021-09-29" version="1">MDKRAAEGAAEGAAASAHKRGRWDAGPAPGAAVGVPNVTPNPAAAAAALAAAVAAKYAPPIGVRPPMPSLGVPSLGLTPGAAAAVAQAAAAALQKLPLVTAAAPSAAGVPPAAVSTATGAAGAAGEAASKPSLSLEALEKAKKALQLQKEIKEKLAKSKLAQLASKLPAPAAQGPAAPNGSGAAPLLPPGVRPPIAAAPLAPPVRPPPGIASVLPPPLAPLAAPQPEREPEEEAGAFHDPILDRGAAGRRGERRRRAGFDFVQEGRYQREAELFRMKSQLGSGAFRKGAPRVSGPLSGPGRLPLPGAPPPGTAPGAAGAGGGLAALDANLVPLGVREVVPQREATPVPEAQPVPAVEWWDRGLLAHGSLEADVPELPAAVLPPRLLPSRVKDADGDGEGDRMAEGDGEENGVRVVTLAQAAEATAAGRQQVDAAAAAAAAGHLGAFQMKDARITIYVEHPVPLDPPAEAPPPPPQPLKLTAKELKKLRTQRRLARDKEKQELIRQGLLEPPKPKVRIANLHRVLGTDASLDPTAVEKEVRKQMAERQAAHEDRNLARKLTPAERADKKLRKLFGAAAVEAGVTEVAGAGKKGGAAAAAAASGAAAAAAGVDLVCSVYRVGRLTDPQHRFKVDVNAKENHMTGMTIISDGFCLVVVEGVEKATRRYLKLMMRRIDWSTAPATAPQPGGGRGADGDADMEDEDEEAPPNVCTLVWQGTVLRRAFTGFRAETVRSAAAGRQLLEELGVGHYWDAAAGATEGESVPYTV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W4L6</accession>
    <name>A0A835W4L6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="3">1.3.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_010285</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="9">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Dus family. Dus3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="3"/>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440397.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W4L6"/>
    <dbReference type="OrthoDB" id="259935at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.70:FF:000494">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="14">
        <location>
            <begin position="4"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="315"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="315"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="337"/>
            <end position="359"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG2440397.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="359" mass="38970" checksum="CE6A72A1F45CEFDA" modified="2021-09-29" version="1">MFGFQVACKTISDGIAASKLAKEGGAQFLDINCGCPIYEATRRGMGSAMLRKPRALAKMVAGIAADSELPVTVKIRLGENDKKIVVDTVVDYLHRAGAAAVTVHGRTAEQRYKKAADWAKVGEVARSTPVPIIGNGDILTHYEAHARRAESGCAAVMAGRGALIKPWIFQEYKEGREWLPTTAERVGVYRLLVSYMKEHFGDDERGWRKAWYFFPWHFDFLTRYRPLPEAVYGSASREHPLIMTRMDLTDARVGEEGPEALGWAERLLRCEHPEAHEAIAAALWDAGSDADVMVALERIGQEHVAAWEEAVRAGGRGGDAARGGGLGVGGPAGGAEGEGREGGKRGRGSRNDDAELERG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WBF4</accession>
    <name>A0A835WBF4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_009161</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000029">
        <property type="protein sequence ID" value="KAG2444223.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="550493at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24055">
        <property type="entry name" value="MITOGEN-ACTIVATED PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
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    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1102"/>
            <end position="1497"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="46"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="259"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="660"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="706"/>
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    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1160"/>
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            <begin position="1637"/>
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            <begin position="1676"/>
            <end position="1833"/>
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    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1893"/>
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    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1974"/>
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    <feature type="region of interest" description="Disordered" evidence="3">
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            <begin position="2161"/>
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            <begin position="2497"/>
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            <begin position="2578"/>
            <end position="2600"/>
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            <begin position="89"/>
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            <begin position="144"/>
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            <begin position="2259"/>
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            <begin position="2282"/>
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            <begin position="2301"/>
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            <begin position="2524"/>
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    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2444223.1"/>
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    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
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    </evidence>
    <sequence length="2702" mass="271373" checksum="2D5A20146E13CA77" modified="2021-09-29" version="1">MAGASLEGLQRRRLLALQLGLPQPPRASEASRLVAWLGVQPALFGTPRHLQPPTETLEQLHSPGQEGQEQQKLAGGSLEASGLDDLAATRRRMVTGRQALRNRRGARTRGRVPQASQPPQPVAVLYPPTVALVDAGCSSGGASGSSSGSSSSSSSSTCSASGNDNSRDSGSSSTTSSSSSRGKKSTGGSSARTAADKPTSLTAAAAAPVFLSRPNGPPAPELWFLSDSGSDTDSDSGPQPSRMRFRSCRFVADLCRPWRPASRGPAAARAASGGGGGGGGDSRGSSSGCGGGGGGMPPLERLRADLVKMQDQRREWRRIARREDWVAEEAPSAQLRAPGVQAAEGASDTAGTGAAAAAGAPGLSAAGVVYGYCRPLDARERLARAAWRAARSDAVAAALPALESRACAERIRENKEMVSIMQIMQMTPQARNSAEALMRAFQQKMLQSQARMQAARPFCQEVGRAALEFVHDLDTDAGRCRAAAAAARATQAAAHVRVLGFPEEEEEEEEEEGFGAAPAPPGAANVVAGTAGYCPSPQLEAETGMVLLWALAGMRAARLLGRRRECGVAALCRGLWQRLQRRGGGAGLLVHGSGGPGGGPGGGHLLTSIPPLVSEVHRELAVTELAARLRRLQHRALAASLTAGPAATAASAAAAAAATSPSSSAAPPASTAAAAAADQPSGQPEAWLRLARMSLGAAYATAAAAASSPAPHPSSSASSSNSTTTTTTTSSAAAASAAAGVAQPALFSPAGAAAAAAWTQLMARAGGAAAALWGPLLRALVEEEGLRRSVVAPMPPSGTQSSHTPPDQLLRSAYRSRGVAGVAAVLARADPGALAAVAGLLPPATAVASGVSAAAGVTGGGGGGGGGGAGVAAFGDLYWRLDWLGFFPVVTLGEGKPGARREPAQPTACAAAAAPPYAAAPAAAATSGNAVRRQEAVLVGRAGCDDGRSGLQRLGELCAWLQAGRPVACAGGAAVWLVLTQLQQLERQRAAAGVATPAAVPAGGTIAGRGAGGLGVAWLPHRLVPPEEARHAAPARWLQPDGEMGGCCVVLQPLGPLLPPSKDSSRTPAADQCATAAWLSGAEALRMKNNPSSDSLSLVHPYLTAAVAQTGRAALVCEGAEALEHAVAAMCQARAELLLERPSRQLVCVAQPVPLALTTATGANNDPAGEGGKTGTACCRSKSRSRSRGGSGTARGHSAGVHREQREAGAAPAGGGGAGGMAEVEVEVERTLLHRDIKPSNILVNSEGVAKLCDFGLARVLPRSVAPSTASGSASPDNASMCSAGGSGSGSDIRNQHQHQRYVAGMVGGPCPGAPHHPLPAHQQQQLLSSYVVTRWYRPPEILLSQSYGPPADIFSLGATIAELAVGMPLFPGASTPDQLNRLCRCFGPLPPRMSAALEAMASRSAATPAVAAGLGVVGTQRGRTLKQRLYGCCDGTGGRTCTGVSAAAAVAVAAPSPRRSARAEPDPMLLEFLQACMELDPAMRRTADQLLDLPYFDDVPQLVAASGSPALYELLTMEAAKRSGGAAAVSAAAASASTAAAAAAQQVLQEETAVTAVRVSQLRSRVAQGAAAAAAVDKEPETLHDGITRRLRVVDLNGQQPQLQLRALAAAGEDSAVAGSSSSGLVYKLAVAPHTAGDRHAPSATNTPEGGATPQQATTPMSVISAVSVATSLLSFLPSPPQPPPLHHPQEQEISFGDGAVPSYHRHQHQHHHHQPQVHKHVVVHHADDPQQHSNAHHGLHAQPRVADSQCRVVDTQSLSAAHAAATGDDPLASTQQHSQQLQRASSPQTSPEAAAAAPGPPPKPGQAAVLASQPSLSTANSGGSSASPQPLAFIPMDRAQSCAASDCCGLSTLPHNSTIAGSMTMGAELETSAFASSSTSGFVAFNSGIPHSTADSSSQSATATATPGSGRAAGPVRALCSVEGTAMRGGSATGVSHIQQELHFQPRQQQLSASSTPPAVLPAASLFPPLAPQLQPAAPASAPSIGANSQQQADAARPADGESPHAVAALNPAAAMNWEQLYSEHLRNNKQNNHAQLESQVQLQPFLAPQQKPAAAAAALSPAASVMLNAKLPMAGATAAAATVSVSAPRYITCQPVAAGVARLPSVPEASASPAAAAGLLQQLTAAMGADLAAQPHSKQHSESSFKEEISFGEDAAVAGVPPANRSNATVASGSPSSAGGSREGRGGSVTRSALPKANSSAANDAGRVVGSPVTIAAVPAAAAVQQSASSAVPVPSAAFTTAAALASAAVVPAAAQQRQQQPLPTQQPAPAVTERPWPGGTGDPGGGGGGTQEPPPAKAVAAAALPTSPTSGHEPKNWQAAVLKTAEAEVAAAAARAAVAQTVAPSPLPLAETRHAAAAVQWRPRASKLLLGVPVDVATLVSAGASSTPAAGSWAAGAGAGAGASQRTSGCCGLEDARAGGGGTGGAAAAAAGGAGAELDVTGGAGGFIRLEEMELLLAAYAHEEQEQEHPAAGEREQQQGHWAACCPAGSGMPAGACGRSGDSPSPASALLGQAAGQERQEEEEEEEEEEEEEEEATVHAQQLLRGQRQLLRRAAGGPSASSPVSRLRSMLTSLSATDPTNSSRSSSGSSGSRGGGGVAMRLCAPSAAAFAAAIAGVSIESAPGAKAAPGWAASLDAPALTAAALEGERSDVKGSRFSSGSFGSFNSLRRPLAAAAGGFLHGQTAVPRVLRLLEHVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WFP3</accession>
    <name>A0A835WFP3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Right handed beta helix domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_008567</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000026">
        <property type="protein sequence ID" value="KAG2446582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="549010at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043130">
        <property type="term" value="F:ubiquitin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051246">
        <property type="entry name" value="WDR48"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19862:SF14">
        <property type="entry name" value="WD REPEAT-CONTAINING PROTEIN 48"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="23"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2862"/>
            <end position="2881"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="2962"/>
            <end position="2986"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="3568"/>
            <end position="3593"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="3619"/>
            <end position="3639"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="3645"/>
            <end position="3667"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="3674"/>
            <end position="3696"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="3708"/>
            <end position="3732"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="98"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
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            <begin position="1147"/>
            <end position="1172"/>
        </location>
    </feature>
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        </location>
    </feature>
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            <begin position="2175"/>
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        </location>
    </feature>
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    </feature>
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        <location>
            <begin position="3433"/>
            <end position="3456"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2446582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="3834" mass="379826" checksum="7B935F303B81F0D9" modified="2021-09-29" version="1">MPYVRCEAAAAAATAAVVPAAAAAAAVAAAAAATAAAAGRNSGSSSSSSSSAGQQQQATGMAELVAVRLGPSLAPLHAAGLLELTGIRVLGWDRAANGSSSNSTAGSSRSSTGSSGSSTQSTADYGVTFVGVPHLLLRDSTLADASLSGVAPLVVCENCTFLTVERLTVEGLEGEPLVQRANGIPSVRQVTHGAVAANGLAAARLVGVSCSRVVNSYGFACVRLSYLPLELRRSALLAAAKATAAAAASSAMAAATATPAQASGGSVAAATNMSVAAEDLAAPAPAPPPAPARAAAELALADVQPPPLLLISDSSFANNSVVCTSNTSSSSSSSSSSSGASGVSGAYGAADGDAKLRLSRFNASSNDVVTGSFESGDGGAVYMLGGGRSSVTITDGSIITSNQGTHGGAVYTESSASLLVEVSGGSRLALNRAGYTGGAISAGGKQDVAIRVTGGSSLSRNVVSGYGGAILAFAKTGSLVVSDQSSITGNVANLYGPSTDSPDGGCGGGAWLEFQNTTLIEISGGSAVANNGAINNGGGLYVWKDMGTFILNGSRMSGNVVQGGPYVTEGGALFVDRSAISIILDGGAVMSDNKAGVWGGAIGIEANGLGDGMVQLGRLVVKGGSSVTGNSAGQAGGAIYLGVKGFVGAVELLEGSRFINNTARDGGGVFYSKVDVVNVTMHGVLVSENGLLPGLREAAGSGTFGDGGVSNVVAVTITNSTITHNVALFKDGGALWLGTSAGTLRLAAGTLVSNNHAAACNTSSSAECGPADDRARGGAIWVGSNAGAVVLEGGTVAAENEAGVSGGFLYVGGTLGSLRVDGGSAVRGNRARHYVGGAVFVALAVGSVEVAGGSSVTGNVAQAYGGFMVAAARLSSFTISGGSSITYNRVLNGSGGVLAIERNVSSFAITGGSDVSYNAAVNGSGGVLYAGNAVNGFMVSGSSTCAGNTAGMVGGMVAADGLARNVSISGGSRISDCAAANYGGFVHAEDSLQHVTVEASTIQNCTAGVGGGAFSSGGQLRNLTLAGGAAVRDCAATDTSATRTGGAVFVGWELEGLTLTGGSSIEGGGADQGGGVYVYGAAKRVSLAGGSSIRRCTARLGGALFVGSEGLTGLSLTGGSSIGSSKATSRGGCIYVGASAADAGSLGADGGSSSSNSDGGSSAGSSSGSSAHDMRGVVLADGSEIAQCTAAEGGAVYVAGGAATDWRLGGGATIRNNRASLDGGAVWAAAAGDWLLEGNSSISENSCGRDGGAVYISDGTFSSSAAGGSSNNGAGGSPGSGATAPPLAPLLLQLTLSGGGRVSSNRAERFGGACFLKGTGGLQLLNVTGAGSAIASNQGLSGGAFYVTGAVVQVSVAAGGAVTGNRGTGGDGGFLATLQDLGRMEVTGAGSTLSDNVAGFGNGGAVFVTGGAASVVVADGAEVSGNRARFGGALAVKGRVVTFELTGRGAAASNYAAYSGAVLHAGGGAASVRMSGGARAAGNRAGLHGGVLWAAGVAEVVMSGGVVVEGNRAVLGAGGVLAVEGAGIGRLDVAGGCDIRGNQAATHGGFVFSEDTTVSEAPAAIASASGGADNAETEPAAAAAAAVDEARVAAWVRLTGSNFTANTAATGNGGGLAFGSAAVAVVGCAVANNAAPGGAGGFLFLGRQWQAADDAAAQDQSLPAANAPSCSALPASSIFSSEDSTYTGNHAGTYGGAVALYGNGSSSSSRTGGSGSSKCETLRRRLVASVVRSQFVENGAALGGGAVALLAVNASVDAGSSGSSTNGGSSTGQQQQAQEVRLSFTGSRLVRNAAGQESGEARSSGSGSSSTPGMGGGAVLIWVEQPAAAAGVAGVNSSLILEGCEFQANAAWIGGGGDIAVWSTAALQRQQQLIAALTGMAAAAVAAATTVATNTSAAALAGGNQHVRITDSTFVNSSAVADGGSLLSVCGCSSDISSTPAVACSIDIRHSTFKGATAGRDGGALALAAGAAAARGATANASSTGAVSRSTPAGLATPVAAAVELESCRFEGNAASGRGGAISYVELAPPGASTAVAPCDGNSGCNSLGTTAPYARGLAGLRLRSSQLLGNRAKQGGGAVALAEGSTALIAGSTLGSNSAPTGPGGAVLARGCNVLWVDGSAIADSRTLASTGGGIYAAGCSLVLVNGSRLSGNSAANGGGMFVSPATNAVTAAVASGGGSSSGSSSSTTPQRRHMLAGDTASPGTDDGFSALIVLDTVFANNSAILPAAPAADDTEAGGAGVGVGPGKGGGVFVQSGVSALFSNTAFTPSNAAASGSALASTQHCSAGSSNISSSSSGLLEDLVRRVSDAESRATAAAGVSEWRDALYTAHQQGAAGCSPLLLVSTAVPPSAMLDEVTQRLPRPVWMEDANMTALAAWCEGSSTNTAESSSGGSRSSAAAASTRVGALLQTLAQCSLPQLSANELATAAAAAVEFPPTQLRLQLPCSMIQGGGSSGSSSKGSSTCFIGGGAIAEAAAADGGSSIGLQQPRSRATATVSVLPEEPFAMRVQLVDAHGGATTPVASTYKVTLSLRVLPPPSAPVWSATSPAANSSSNQSSAPSSSGAAAPTAAVGTAAWLDGLCASQQQLLPAADAAWWWCDPDFANLDVGRAQSLTQVLDMGSAEWPRVLLRGWPGDYLLVLRATGPLQVAELSVPLEPQQLQQLTQRAMAGELARAYDGSEVMCKECPNNADCPGGRAIVPLPGYWHSAPNSAAVHACHVPDACLAPSDVAFILSRSGFGSSSFTNQLPPPTVGSSSTSGDGSSSNSADGGSSDVDGVDQRTQALLACQSELFTTGAPPYGNTTLGWGNASSATAGCSLELYMQMQCGDGYTGNLCAACLPGYAVSQDLECDECPSMARTLGLSLLAFFGSVALIMYTAVASLGAATAGASEGTGVTQGDIMKILIVHCQYTVIITRLNIDYPHVITTLKAGLGSITGAASQGISFNYGCLVARSPTGQRALAQLSGSLLVPCVVIACSLALWALRYKFLHRAVLRRTRAMHGHRHGADALPSFNYYNESMAPVEEEASLEDGSGSIAGRGDSGRSCRSRGSGREAAAAGGHALHGGCTAEPAAQQQQQQQQQQQVADAAAPPHGASAATAAAAAQAEAAAAEAPMSSAADAAGWSTEELVLRRQCSSTSHHSPTTNSSVDDTPLAPASLHHYADTQQHDQHPQQQPAPAITPLLQPAPPAAPLPPPAAPRPPLPPRAPSYEPGAAAAAAAALLPPAAAVAQRTHSQTSWQQPTASTHSDTSQPPQSRRASYGGGGECGSTPQNAPATPSRLGLPSQHPPPPEHPSSQQQHNQHQHRHYQQHASSAPQSRQHSVSSAQQQHPHHRSSQPGSRHASYVGIVQGPSLSPSPSTTKQQRQLAQQVLLGSNQNPAPPLPTAGSSNPLQPQTSSQRPSASDPPPGTSTRSHTWSYLASRRNRDRPSDGGGGGGGAGPRGGRNSSGGGGGMSERVSHVSNVSQAMRKLGSRALMLVKPRDTPTSALALADTSLGFWQQLGLVLMSGVFVLYAGWAQAAFSVFSCYRIDEGGSLVPENERANWSRGYWFLDMQQPCYSGTHMALYLPIGIVSVCLFCLAPPLSSFLLMWRARHRLAEYRTQQMWGFMYKRYRQQFFFWESILQLQTLALVAVDVFGRGMPVLYQALLLLAVLLSIASINMFCAPLRTRRLVVLEFSSHMVLCLTITLSLYFIPTDALPLSDGEATAVGAIMFALNICLLAAYVAYILALSWPSFKPHMDRAGAAARRALRGRGVSSAADAPSQYATKKGALDVEDKGAEAAAGEGAVESEAHGVLASEAMAGADVVRAEAAGARSRQQESACMRDMAIGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WFQ8</accession>
    <name>A0A835WFQ8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008198</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WFQ8"/>
    <dbReference type="OrthoDB" id="10504232at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="92"/>
            <end position="113"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2446623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="114" mass="12046" checksum="6D1F2D77C8B860C1" modified="2021-09-29" version="1">MACVKLNICVSAARVCARSSGPKPVCAFSRVGLDEGVKRPVTCAAESGSQLSVAGDADSIASLTKALQQKDAEVQAGVEKYNQARAEAKKYVALYFILLVAALVMYCIATGRFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WG28</accession>
    <name>A0A835WG28_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Tafazzin family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HYH02_008079</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1'-[1,2-diacyl-sn-glycero-3-phospho],3'-[1-acyl-sn-glycero-3-phospho]-glycerol + a 1,2-diacyl-sn-glycero-3-phosphocholine = a cardiolipin + a 1-acyl-sn-glycero-3-phosphocholine</text>
            <dbReference type="Rhea" id="RHEA:33731"/>
            <dbReference type="ChEBI" id="CHEBI:57643"/>
            <dbReference type="ChEBI" id="CHEBI:58168"/>
            <dbReference type="ChEBI" id="CHEBI:62237"/>
            <dbReference type="ChEBI" id="CHEBI:64743"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:33732"/>
        </physiologicalReaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:33733"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion inner membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
            <orientation evidence="1">Intermembrane side</orientation>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="10">Mitochondrion outer membrane</location>
            <topology evidence="10">Peripheral membrane protein</topology>
            <orientation evidence="10">Intermembrane side</orientation>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 12">Belongs to the taffazin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000024">
        <property type="protein sequence ID" value="KAG2446924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WG28"/>
    <dbReference type="OrthoDB" id="193467at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005741">
        <property type="term" value="C:mitochondrial outer membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006644">
        <property type="term" value="P:phospholipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07989">
        <property type="entry name" value="LPLAT_AGPAT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002123">
        <property type="entry name" value="Plipid/glycerol_acylTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000872">
        <property type="entry name" value="Tafazzin"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497:SF0">
        <property type="entry name" value="TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12497">
        <property type="entry name" value="TAZ PROTEIN TAFAZZIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01553">
        <property type="entry name" value="Acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00979">
        <property type="entry name" value="TAFAZZIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00563">
        <property type="entry name" value="PlsC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69593">
        <property type="entry name" value="Glycerol-3-phosphate (1)-acyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0012">Acyltransferase</keyword>
    <keyword evidence="6" id="KW-0443">Lipid metabolism</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="5" id="KW-0999">Mitochondrion inner membrane</keyword>
    <keyword evidence="4" id="KW-1000">Mitochondrion outer membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Phospholipid/glycerol acyltransferase" evidence="13">
        <location>
            <begin position="30"/>
            <end position="163"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004137"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010524"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022792"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023315"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00024323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU365062"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="SMART" id="SM00563"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG2446924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="245" mass="27363" checksum="5C1FA3A70FD14078" modified="2021-09-29" version="1">MLNVINTTTIHGQDRLIQAVEEQKANGRGLITVCNHTSMFDDPGVLSLLMPWHWLWSEPLTEKVRWSICAKEVCFKNELLRHFFLNGKTLPVERGKGVYQPVVSIAAHTLAKGGWVHLFPEGRINYDGKLGPLRWGVGKLICEARQLNGGRDPALLPFYHSGMGEVLPITMDRLNVGRSVEVRVGEHIKVDDLTCNCDSPDMAVQQETWKAITARVRAALLELEAQCPTNPDQTDVAPKREPPPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WGP8</accession>
    <name>A0A835WGP8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_008253</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446685.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WGP8"/>
    <dbReference type="OrthoDB" id="545792at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052886">
        <property type="entry name" value="LCS_TC/CRSF"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23261:SF77">
        <property type="entry name" value="GROUND-LIKE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23261">
        <property type="entry name" value="GROUNDHOG-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="72"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="297"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="368"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="522"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="92"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="109"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="302"/>
            <end position="328"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2446685.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1106" mass="112093" checksum="A921A4F1BD221B7B" modified="2021-09-29" version="1">MVVMALTPGVEGRVIRLEERAPSITTLIVDAMKTAAASSTGPVCTGAEPPVPAAAAKEAAALAPARFSGFATECPDDTGRPHHSPFASAGSHDSDTGSQHRDAGDRNTPDATPSGSASSTLVPACKLGRPLLTPQDQHRLQQLLPGVLQALLPSLLPALLPGAVAAAMPSASAAASAAALTAGTSTAASAAAVAIAPAIVEAALPAALASVLPQALSAALSALLKSAGGEELSTAATAHQSQQAISGERQASLDQQGAAEQQLVRMLFGAEAAAEGAAAAPAAAAAASLPVTVPKPSELTVGSPSGSAAAHSHNSGSSSPTERSSTAVAAAAAGNSMFSRRLSETTVTGSGGVAAVAGSAVIAQRAVAQPPHAHHAHAPVAGGCSRSSINSGNHAPHWPGADGESSVEDALSTCSADALVSPAPFGDACCGNSSAPGTGAAVNSSANSFLFSASSQTHMLPAGLSGSNIEGLSEVSGMYSMSGARDDLLSPSGNGPSPAELLMAAAGRVNGGGANAATMALLAQQQQQQQQQQQQAAAAVAAAQQQQQQQQQLQQLQQLQALVAAGAAGSDLGAPASPPLGLAQWRRDTDASADLWGQADADPLSFAAASLALNQQQQQACGLLQQQQQQQMLAQSLAAVAVSNASGRQLRAEDLLALGGNPAAAAAQLAAAAAAGGAMGSSADLSTYMDAALRRMLLVSPQVASELARACGAFSGAQAQLHHLCCVIAEQLLDVAAMAPEVAAALLRALASHRARGAQATDVDPRVMGRILQLLRAGPAGRQLCLVSLEQWVDGLSRIHKRRAYLDTILHNYQLTLKRLVQAMGHQVHAVNMSLPRQLLNDLSPRALLLLTAELAPYPLLQPRRWSEEIIWAISQMHTMGVDMPLAPGTPAAAPAVAGQQPPVTAFQWEMRRALSAAAEDIAASGGAGGSPTGGSSLASLTGQLSSLGLGGAAAAAAGAANANCPNGAVPWAAHAALHRHLLLGLRRIQSRFFSERLRKVHGLYGEAVDSLLRGSLPQDVLVPEREMVVLVLVLLMLECRMRPEEFDAAFARDLQRCLAVSPVEEVAARLRCGLVPDSPLRIDPHKSRALSQLLKLGALGGPSPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WGR2</accession>
    <name>A0A835WGR2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glutaredoxin-dependent peroxiredoxin</fullName>
            <ecNumber evidence="3 9">1.11.1.25</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_007862</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Thiol-specific peroxidase that catalyzes the reduction of hydrogen peroxide and organic hydroperoxides to water and alcohols, respectively. Plays a role in cell protection against oxidative stress by detoxifying peroxides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[glutaredoxin]-dithiol + a hydroperoxide = [glutaredoxin]-disulfide + an alcohol + H2O</text>
            <dbReference type="Rhea" id="RHEA:62624"/>
            <dbReference type="Rhea" id="RHEA-COMP:10729"/>
            <dbReference type="Rhea" id="RHEA-COMP:10730"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29950"/>
            <dbReference type="ChEBI" id="CHEBI:30879"/>
            <dbReference type="ChEBI" id="CHEBI:35924"/>
            <dbReference type="ChEBI" id="CHEBI:50058"/>
            <dbReference type="EC" id="1.11.1.25"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the peroxiredoxin family. Prx5 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.11.1.25" evidence="3 9"/>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447116.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WGR2"/>
    <dbReference type="OrthoDB" id="1882547at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008379">
        <property type="term" value="F:thioredoxin peroxidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042744">
        <property type="term" value="P:hydrogen peroxide catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd03013">
        <property type="entry name" value="PRX5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.30.10:FF:000020">
        <property type="entry name" value="Peroxiredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037944">
        <property type="entry name" value="PRX5-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013740">
        <property type="entry name" value="Redoxin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013766">
        <property type="entry name" value="Thioredoxin_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430">
        <property type="entry name" value="PEROXIREDOXIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10430:SF16">
        <property type="entry name" value="PEROXIREDOXIN-5, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08534">
        <property type="entry name" value="Redoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51352">
        <property type="entry name" value="THIOREDOXIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 9" id="KW-0049">Antioxidant</keyword>
    <keyword evidence="6 9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="4 9" id="KW-0575">Peroxidase</keyword>
    <keyword evidence="7 9" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Thioredoxin" evidence="10">
        <location>
            <begin position="20"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="active site" description="Cysteine sulfenic acid (-SOH) intermediate" evidence="8">
        <location>
            <position position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001711"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010505"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00013016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022559"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022862"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR637944-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU366011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2447116.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="179" mass="19319" checksum="0D4CB3CDA617BE6D" modified="2021-09-29" version="1">MQRTAVRSSHGRVQVVTRAIAVGQKLPEGKFKYFDGEGQMRDVTTDELCKGKKVVLFAVPGAFTPTCSLKHVPGFVDKADEFKTKGVDTIACVSVNDAFVMAAWGKDLKAGDKVLMLADGNGQFTKALGVELDLVDKGLGLRSRRYSMYVEDGMVKVLHLEEGGAFTVSSAEDMLASLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WH24</accession>
    <name>A0A835WH24_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007857</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447109.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WH24"/>
    <dbReference type="OrthoDB" id="545599at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019410">
        <property type="entry name" value="Methyltransf_16"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614">
        <property type="entry name" value="HEPATOCELLULAR CARCINOMA-ASSOCIATED ANTIGEN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14614:SF157">
        <property type="entry name" value="METHYLTRANSFERASE TYPE 12 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10294">
        <property type="entry name" value="Methyltransf_16"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="293"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="248"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2447109.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="526" mass="54151" checksum="3F6A3902B2ADBC78" modified="2021-09-29" version="1">MLKVGADEEDFLELLVANERVQNLIDRIRARGNPTRQKQALLQLKQAVESRVTYAEEARQAGVVPVLTRLLGLTDDEEVLDAASAVIAACSGPMATAGKVSTYSYEGCVVRIREAALGDGLGAKVWQVAHMLCLELAAQRAAITHMALAAAGSAETEAASIAAGATGEGEEQGEARQWDGVRVLELGSGCGVCGLAAAAMLGGSCSGAAGSAEGSAAVHVVMTDVEGPVLRNLRACMHLNADADAAAAATAAADQQQQPEQQQQQQALPTDEELFDDAEEVEDFGADLVFELAGGGGDDADSSNGCGGGGEDRAAGARATGPDAWERGNTSVRLLDWMESARALDEGPEAAAVAAAEAAAKGGPDMPPRVALEERFPLIIGSEVMYERAHAELVAAVVAHRLAPGGGALLHCAVRELKVFAHFAAECRRRGLRYRRRVVVPAAVFGAAACTSGVLLDAATAGAAVGTCTAAAAATCAGAGGLVLCPFEGLLGRADEYEGGIVLMAVDHSAAPCEHWYRDDWEEVVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WH38</accession>
    <name>A0A835WH38_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HYH02_007655</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Secreted</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000022">
        <property type="protein sequence ID" value="KAG2447325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="543368at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004866">
        <property type="term" value="F:endopeptidase inhibitor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041246">
        <property type="entry name" value="Bact_MG10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001599">
        <property type="entry name" value="Macroglobln_a2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13062:SF12">
        <property type="entry name" value="ALPHA-2-MACROGLOBULIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13062">
        <property type="entry name" value="COLLAGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00207">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17973">
        <property type="entry name" value="bMG10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01360">
        <property type="entry name" value="A2M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01186">
        <property type="entry name" value="EGF_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50026">
        <property type="entry name" value="EGF_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="10" id="KW-0245">EGF-like domain</keyword>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="12" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-0482">Metalloprotease</keyword>
    <keyword evidence="4" id="KW-0645">Protease</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0964">Secreted</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <keyword evidence="12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="55"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="13">
        <location>
            <begin position="3099"/>
            <end position="3132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="94"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="290"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="505"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="676"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="796"/>
            <end position="827"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1144"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1319"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1701"/>
            <end position="1721"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1861"/>
            <end position="1891"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2233"/>
            <end position="2271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2542"/>
            <end position="2579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="112"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="296"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="693"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="1146"/>
            <end position="1157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="1320"/>
            <end position="1330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1331"/>
            <end position="1345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1861"/>
            <end position="1883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="2233"/>
            <end position="2251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="2252"/>
            <end position="2266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="2557"/>
            <end position="2579"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="3103"/>
            <end position="3113"/>
        </location>
    </feature>
    <feature type="disulfide bond" evidence="10">
        <location>
            <begin position="3122"/>
            <end position="3131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004613"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022525"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023049"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50026"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG2447325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="3143" mass="315894" checksum="5A3F03D851E973F2" modified="2021-09-29" version="1">MFGSSMQRVSGAATPRRGNGSAGAGAGSSEDPTVTAPDTPPRSPRVGSWRGSGTITVVVTIAAVAGALMLALAAYSEFASRPALYHRPGASHPAHVGAGPFRPHSSSSSSSSGGGGGGGGGASGGSGLTGWVKAHLYSSSSSSSSTGGGSGRGGGGGGGASRAFLAEVLPLRVVLTAPLELARPRDDGSGGGGGAVQVQGRQALTVVFTRPVIALGADFGLSPEQADKMAPFRLLNCPVPGKARWVTTTIYRFDPDLHWPSDLDCELTWNTRLVSYDGVPLQLELVRDGGLPPGVGSSSSSSSSSSGSPIPASVRLATHPNSMWVGGVSSEHAAALTGGLWDPMTGFPDEALPEMPPDGRLRLSFPYPVNLRMLQQELQLFEAGDTLWPGGSSSLPMDVSRCAEPDFTPWRPFLAAAAAAAATAAGGAAATAAGDAAESRLLLLDVNATCAEVKPREPPEPGRRYTLRLPRGARYNALSGPLGRTAEVTFGGLLPFTLPFLDYARQRGGGGGPGPGPGSSSTGPGLDAPAHASRRLDVWLRHGLAEGVEPRDLAAALRVCRLTPPLGEGGVAAVLPQPAALSWGSCAEQLEFGLELVGRGRARLAVPGLVPGGRYRVEVRPAVAAAEEEGGGGGGGGGGVRDGYGQLLQASHAEFYMTHVGFRLIMPYGTSGGGGSGFFITEDEQQPLPLPQPRSGDGSSSNGSSSSSSITAVPLTAWPYALHPPEALSPVAEQQRKRWGGGGGEEWSFMQELHMWAPDLSAARDGAKDDKALVAVLKILQGRMYNVQLKDVLGPPTHTVKVPPELRTRPKWVPGGPGAGGGSDEEAAGRGWRLLELPLELQSMEGGAEEGGAAKAKAAAVARSPVRVVAACCTKYGPTPASAYMQVLLNSSLSLSVVRAAGSSSSSSDGVDGGGGGGGGNTLTAWLLEGTSSATAAEGGGGRGSGGAVKGAAVHFYMSPNWDADPARFASCTTDAEGLCQVVVKPEALQNGGGMQQQLMAVAVAPDGRLALLPAAGWLEAPPPRPRYVASLVADRRVVVAGDSLKVTGFIQQVVGRALRLPTGRLQAVLEVSPPWQPPPQGTGLPLQTTTATTAAMSTTAAVTDGMATRAGVTSATMASGPQGRRQHLAAAVAAAGFAASHPGFAGTGGGSGGGNGQRQQQQGPSRVVVDIDPESGTIHGEIPVPPDARLQPYSILLRLPPGDGRSSSITKIIKPARAGRGSGSTAGFAATAAVGGRTFTVGSATAGEMAGHAGARGVRRVLLQGTERLAGSEPQATQQGTAAAGGAEAAAVLHSGGGTGGGATATAAEVAPAVLPDALTSNANPDANTSSSGSSSGSSSNSSSDEAYDGTAGEYKDDNGGAGGGAGDDGASKLRALGDVDWWEAAASFAFTVADPRPPTAELKVDVPPWAPPNATALRINVTAVSYIGASVDGAEVSLTWRTAKTSDVLKLVTDVSGRAHTVLNLAALPETNRSEPYDSLAVDAEWIGPTRERITQSKQITLADGPARLSLQTSLDTDVPGVAFAVGADLTSNVDGSAITGVAVTATLKPDTTPGPSSAACADTPSCTTTSGAGLDAGCQLALPCVGRFVLQACAEVGDSEGVGAAAVSGAAVGGAADSSRGGKRRVCDVRYLGRNASEWAAAPWSAHRVPEMKLDRDTYAAGEWAQLRLQMPWPGARLLLVWGNEGGVRRTVVGLDPAPSQVAAGDKQQEQQRPGGDLKPNALALVRFGPLGEECVGGCSLVGVLDVPRASPAVMPLPQQVPTSHLFDPRAPHSHQLGTLHLAVRPPNTLAVSLGVTAPAPAGAGAGAAAGAGGAGGGGGGKGPAVVAVRDVGGEQLVTIEPGSQAEITITVTDAADGTGTTTTATATETTTSKGSITPGSGSGSGSGSGPYHVTVYGVDKSFLDLLPYPLPAPQQEVVLRLAASVAAYGPSAYRLAPGAVQAVFAKLMSRLTGQDPWLPTDTYVGQPQDGGFAPRRFGRFGGGGNPGGGDYPGGGGGPQYAVDANDTEYLSHFYSVATLMPGDGGGGGGGITYSRMRTAGTANMGETLMAADAAGAGGGVAVAAMAAVPQLEMAALPRAAAMTKSAAMAVDDVFAAAPHADGAGPPFSSGQQPAATLPPRSSLDFIVTPLFANAVTDGSGTARFTFTAPPNLGTFVLRAFAASGAAAKYGSGEAKLAVRRALSLTPSVPRFVRVGDKFEAGVVVTVSSAPASVTVNVKVADVLCGAGSGAASSGAGCGGKARASAAKGRGGGGDGGGGGSDGAPGALRLVEGAGAATSAGPEASKTVTFEAGGGLQQEVRFSFSAAAMGRANLTFTAAESAGPSGGGGGGGGHSSSDSLSVDLAVHGQQGDVWVATSFALKALPASDVVQWQEGLALPDAVPGSGGLALTAGVGYFPALVSAYDALMQQEEDRLYPEAPAALQWALLPPLLRTYGQPPPEPAQQAAVAAAYVDLQGLSRQPPVGLVWRNAYPSTRCDTYLNSRALLLVGLRSCASLLLPPPVAAATSTSSTGDATAAANDAAWHVYLHRPLPSCAAFPVTGGSSSSESHDAAAADPKQQQQQQQQSQDRDQGAAAEGQLSATWAAALAQQLVADAEASRQQGYGRLPYGDMGALAWARLALGANWDPRASGASDQVAGDLSLATLVAKTGEKSELDWGLQTRVAVALLMQSLPEAERPRGGTTSLAAVLAELTSSLRVQGRTTYVAAGEGAASAASLDTQALALLLLLRSGATHQLLPKLAAYVADPSGSGSAPMSYWAAPRLSYIDQALVTAALAEYDRAVGSAQPAVNVTAVAGGEVVLRANFRTGGNTRPVTNTTAWHTIFASEKNKLAAAAGARKSDNNASANAATHGTLNLQATGSGEVSVAASLHFIPSALLAFPSYRGLYVEAALQQVDPRTGSPAGGRLAAVPLGSVVALTVQLTTPDDLGAVTLSVMMPGGLEPIDPNVPGASGGGASTSTAIRTMPSGRQYGGGMSSGGFPSSYGGGGMPPAGTCAAGLLADLPWGSYGGWGWMFPVCPAQETRPAVVTFNYWALRAGTSSVVIKAVAASVGEFVVPPIRAWAEAQPELMGMSAASRVRVCADCKAPESAPPAPPPRGCPGDCSGHGLCNLAAGTCLCGSGWEGEDCSARQKARRLRGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WH44</accession>
    <name>A0A835WH44_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007758</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000022">
        <property type="protein sequence ID" value="KAG2447432.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WH44"/>
    <dbReference type="OrthoDB" id="551027at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="164"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="201"/>
            <end position="230"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2447432.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="339" mass="33589" checksum="A55FA77E76AF9FA0" modified="2021-09-29" version="1">MREALRALAQSELLSALLRDVVRHANISAGAARLQDAGSQTSLEVSRIIQLSEDNEGAAAGLQQALAASQRHQAALQSELRAAQEAIQLMVPRIHELQLRNGRLYEALGRAHGAMQAAAAQVASAATSAPGDGTTSPLMAGRSLSQLVAGLRDAMAEARRTMAAEEEEGEQEGGAEAEGLSSPMPAGLASGGSTRRRDDASVSPDQAASSPASARRRNSTPSTSGVSSVAGAGAGAGAGALVGAALQRAMSSAVNTPRGATPRAAAAAAAAAAGVEGCCSGVVARAAGLTPRSGMGKLGVAGGGTVAPVPPLSLSKVLASDVPARSLTQAPPQQPALLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WHS7</accession>
    <name>A0A835WHS7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007586</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WHS7"/>
    <dbReference type="OrthoDB" id="522997at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="126"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2447671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="149" mass="16305" checksum="CCC38950AF6E120C" modified="2021-09-29" version="1">MLSQQLTRRQVSSARPSAQRPVCSRPCVRARIFRRDGPVAVEEVAVDEFNAPTKRQREQLKRTLQELGFTEQAADILAFSKITNSNCDLLIGDIRASFGVYQAPPPAGPVESVQNGVQDLLERLRLPFLGVLVAAGVFAAISNQVTMLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WHU4</accession>
    <name>A0A835WHU4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="17">Elongation factor EF-3</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_007524</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="2">Protein biosynthesis; polypeptide chain elongation.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the ABC transporter superfamily. ABCF family. EF3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447603.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WHU4"/>
    <dbReference type="OrthoDB" id="2110130at2759"/>
    <dbReference type="UniPathway" id="UPA00345"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd03221">
        <property type="entry name" value="ABCF_EF-3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd18626">
        <property type="entry name" value="CD_eEF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.990:FF:000002">
        <property type="entry name" value="mRNA export factor elf1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000193">
        <property type="entry name" value="Probable Elongation factor 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1390.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.990">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050611">
        <property type="entry name" value="ABCF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000953">
        <property type="entry name" value="Chromo/chromo_shadow_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015688">
        <property type="entry name" value="eEF3_ABC2_chromodomain-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047038">
        <property type="entry name" value="eEF3_chromodomain-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047036">
        <property type="entry name" value="EF3_4HB_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211">
        <property type="entry name" value="ATP-BINDING TRANSPORT PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19211:SF5">
        <property type="entry name" value="ELONGATION FACTOR 3A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24984">
        <property type="entry name" value="HEAT_EF3_GNC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24987">
        <property type="entry name" value="HEAT_EF3_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00298">
        <property type="entry name" value="CHROMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50013">
        <property type="entry name" value="CHROMO_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0251">Elongation factor</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="10" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="513"/>
            <end position="744"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="14">
        <location>
            <begin position="764"/>
            <end position="1075"/>
        </location>
    </feature>
    <feature type="domain" description="Chromo" evidence="13">
        <location>
            <begin position="893"/>
            <end position="925"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004815"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50013"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG2447603.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="17">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1075" mass="115745" checksum="490A5A3391ACF240" modified="2021-09-29" version="1">MTFNPAAAAFQPGAGFLSPEVAAINDLMDRLSLACKEEAPRAAAAAAPKPVASASAAAPKPAAPSGGIKIMRAGAPAAPAAAAPAAASGWGAGGASSSASRGGVSRDNAAREIGEYVKARGVRVLKTSGLRDRLALMADDQNNHVAREAALLAYAALCDSVGAAVEPFVAPMLPVFLERLSDKIAVRAAADQACQALARLLHPCAVPRVMPAILSGASPAKKWQCKEGAFKIISTLCETAPDAVQAALPDIVPVVSDGIVDARDEVKEAAVAAAESAFALAGNRDIAPCVPSFLSCIRNPKETAEAIIKLSGTTFVQAVEAPALAVMCPLLIKGLKEETAIKRKAANIIANMSKLVLVPADADTFLPKLLPRLEAAANETPDPECRSVCAAAVTTVRRVAEAAHSARLAEDDERKVLKEAEVEAMLVAILAANGADVAGDALLATAVSYCAAIATSMVNKKQTDPAKWQDEIIEPFLLSFLDDGDAAAAKVAEAWAQQAEAASHVVVDDGLSDDDEDVLCNCEFSLAYGGKILLNNARLRLKRGRRYGLCGHNGVGKTTLMRAINNEKVEGFPPKDQVCSVYLESDIDPAMAEYPIVEFVFKDPTLQITAKPPSMEEVVEMLRNVGFDDERQKVQVGSLSGGWKMKLALARAMLMHPDILLLDEPTNHLDVVNVAWLEDYLTRVIPRVTCLIVSHDSSFLDNVCTDIAHYESRKLKYYHGNLSEFVKVKPEAKSYYTLAAATLRFNFPKPSFLDGVTSGEKPVLAMKKVTFTYPGASKPQLEQITCSCRMSSRVAILGPNGAGKSTLIKLMTGELKPDTGIVNKHINVRVAYVSQHALHHLEDHLDKTPNQYIRLRYGKGEDKEEAEKVTRVLTAEEEEAIKKQIWVIDGQNRVLEKLLGRRKKKKSFEYEVKWVGLSSIEFNRWIMREVLVERGFEKLCREMDDKINAEKGEAAARPLTLASVEQYLQDFGLEPEFGTHSAIRGLSGGQKVKLVLAAAMWHCPHLLVLDEPTNYLDRDSLGALAQAIKEFGGGVVMISHHSEFVGALANEVWDLKDGKLSCHAKEEGKEEEAAH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WI62</accession>
    <name>A0A835WI62_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_007747</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000022">
        <property type="protein sequence ID" value="KAG2447420.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WI62"/>
    <dbReference type="OrthoDB" id="539746at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052881">
        <property type="entry name" value="Keratinocyte_PR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48138:SF2">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48138">
        <property type="entry name" value="KERATINOCYTE PROLINE-RICH PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032812590" description="FAS1 domain-containing protein" evidence="2">
        <location>
            <begin position="22"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="29"/>
            <end position="181"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="409"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="187"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="617"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="265"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="306"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="588"/>
            <end position="597"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="598"/>
            <end position="617"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2447420.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="617" mass="64733" checksum="593BF0AFADED59B6" modified="2021-09-29" version="1">MPGRRFIIAILLAMLGLGARGQSSVMLPYISLQAYLNGEPALSMMLQLAIPSYSLLSDTGLKATVFLPTSDAVMSYLYTEFGVSDLADLWSNAVLNQRLLGEFNLRVLPQMIVKDRLLTTAQMTNGTKLRTNASEDVTLVVGKAADGSVTITGPQNTAKVVKANQLLASGKIVAHLVDKVLLPPAIADPPPLDESPPPPPVRSPRPSPRVSPAPSPRPSPSPSPSPSPSPSPSPSPKRSPSPSPSPPPSPSPSPSPSPEKKKKSPPPAARPSPSPRPSPSPSPSPSPSPSPSPSPSPSPKRRPNSQSPPPSPVPSPSPSPSPSPSPSPSPSPSPSPRPSPRPSPRASPSPSPSPSPSPSPSPSPSPSPSLSPSPSPRPSPRPSPRPSSQPSPKPSPSPAPEQVPAFGSFPNLQTALSAIPQLSLLSLLYDTAVQDSLVRITLDAIMLSPFTMWLPTNQAFEAWFADPASPWHWQNDLGQAVGANPRLLLSLLSPHTLAGSQLVESDPNDLHDGSTFTTGLKVLGRPPPGVQFTVRRTDAGVALEGTRGVNAGVVFHVLRLEAALVGKAGVVHVVDRVIVADIPTAAPSHRRQQRRRLGQQGQLQLQQQQQQQQQLQQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WIT2</accession>
    <name>A0A835WIT2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">RNA helicase</fullName>
            <ecNumber evidence="1">3.6.4.13</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_006914</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="3.6.4.13"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.6.4.13" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000018">
        <property type="protein sequence ID" value="KAG2448332.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WIT2"/>
    <dbReference type="OrthoDB" id="10253254at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003724">
        <property type="term" value="F:RNA helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.10.2130:FF:000001">
        <property type="entry name" value="Pre-mRNA-splicing factor ATP-dependent RNA helicase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2130">
        <property type="entry name" value="DEAH helicase family, winged-helix domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042035">
        <property type="entry name" value="DEAH_win-hel_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048333">
        <property type="entry name" value="HA2_WH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007502">
        <property type="entry name" value="Helicase-assoc_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18934:SF109">
        <property type="entry name" value="ATP-DEPENDENT RNA HELICASE DHX15 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04408">
        <property type="entry name" value="WHD_HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00847">
        <property type="entry name" value="HA2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="5" id="KW-0347">Helicase</keyword>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase-associated" evidence="9">
        <location>
            <begin position="81"/>
            <end position="169"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047984"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="SMART" id="SM00847"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2448332.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="170" mass="18977" checksum="E40328FFE776DE81" modified="2021-09-29" version="1">MFLRRQASAHQRAGRAGRTQPGKCFRLYTESSFKKDLQEQTYPEILRSNLGSVVLQLKKLGIDDLVHFDFMDPPAPETLMRALELLNYLGAMDDDGNLTPVGNIMSEFPLDPQLAKMLVASPEFRCCCGCVARACVLQQGAALRVGQAPQARARQAPRRAIGPRRVRHVR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WIT9</accession>
    <name>A0A835WIT9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_007052</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000019">
        <property type="protein sequence ID" value="KAG2448024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WIT9"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032940648" evidence="2">
        <location>
            <begin position="18"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="37"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="51"/>
            <end position="71"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2448024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="178" mass="18274" checksum="29FBD2DFB176C00E" modified="2021-09-29" version="1">MSISALSSALKLRGVAAAAIASLYNYDMFSGAADSNGGGGRGRSGAASSGSGLGGAGGSGRTASGQTGGGPSDASSARSRISQSYFDGFVDLVCCRGGRHISWPFECPRLLGLRRDMEDTLGWAVDAGLREGMHGLRVWWIGQVVGGNDEERDQLLLEVEDEGAGGGAMGLRVAWDED</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJW0</accession>
    <name>A0A835WJW0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_006511</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000017">
        <property type="protein sequence ID" value="KAG2448623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJW0"/>
    <dbReference type="OrthoDB" id="549602at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032959855" evidence="2">
        <location>
            <begin position="24"/>
            <end position="648"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="220"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2448623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="648" mass="68029" checksum="01709C9537B9097F" modified="2021-09-29" version="1">MSGDVALGFLLALYLLAGAPASATSWKWIDVVDALAQMPSSRGGNWRDRRQLQDVPALEQGPLLIPLLPYGLSNQLIALKESLALAAVLNWTVVGYGFMPHYSELAAAAGVDSASNTGDPTVEPGGAVVPITAIPFDTLIDRASLAPLVRIITVQEALELLEREGQRHELAGATAGTAGGGAADSSSRDSRARLQRLQQQHRRILGKGSTSSTGNGGHARAPRIGCGGAGGEGVDDDGAGAGGGSVCLAVDRLVLLRDNGMPDTLHKAEEGGRLDASRAHTVRKKFTCDARGLDWFRQTAARDRWRVVALNGYHCVLPQARRGFKAMQLRGGSDSGCWQAYQRVTALMQRSEAVRDAAAAFLDSAAARALLPGDAVDGGSSERGRSNGAPLVPRVLSLHFRPYPDACLDYFVNMTTFELGAAQEVCSQPLLLHQIVPLAQAFLAQWAAEATEVEAEPAAATRGPAVVFVMSHPKVRKTLSREFERLWAAANGSMGDNGGGGRALRLDQTAGAPPLPRLSFLDLDDVPPALFEAPGSSNSGSGSSSSRRALPVGANSILSVVEQQVCAGADVFIGTATSSISVLVAQERVVVREAGTVGVAGAGHEGEEGGVPREEGEEWLQRVVTEAKRGKRAKNLHIAADGRVTVLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJW4</accession>
    <name>A0A835WJW4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Aromatic-L-amino-acid decarboxylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_005790</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 6 7">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the group II decarboxylase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2449038.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJW4"/>
    <dbReference type="OrthoDB" id="639767at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016831">
        <property type="term" value="F:carboxy-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030170">
        <property type="term" value="F:pyridoxal phosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006520">
        <property type="term" value="P:amino acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019752">
        <property type="term" value="P:carboxylic acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1150.10">
        <property type="entry name" value="Aspartate Aminotransferase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1340.10">
        <property type="entry name" value="dopa decarboxylase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010977">
        <property type="entry name" value="Aromatic_deC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002129">
        <property type="entry name" value="PyrdxlP-dep_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015422">
        <property type="entry name" value="PyrdxlP-dep_Trfase_small"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999">
        <property type="entry name" value="GROUP II PYRIDOXAL-5-PHOSPHATE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11999:SF70">
        <property type="entry name" value="MIP05841P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00282">
        <property type="entry name" value="Pyridoxal_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00800">
        <property type="entry name" value="YHDCRBOXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0210">Decarboxylase</keyword>
    <keyword evidence="5 7" id="KW-0456">Lyase</keyword>
    <keyword evidence="4 6 7" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="6">
        <location>
            <position position="292"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009533"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022793"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR602129-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000382"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2449038.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="492" mass="51631" checksum="98135F5DA891247D" modified="2021-09-29" version="1">MGHAMVDMIADYYESLPSLPRVSPDVQPGFLRGALPPNAPEQPESFEAVMADVRDKLMPGVVHWQSPSFFAYFPSNYSFPAALADMWSSVLGMVGFSWAAGPVATELEMAMMDWLADLCGLPPAFKCNGGAGPGGGVIQGTTSEAVVVALLAARARALAGRPVADRLKLVAYSSDQAHSCFKKACMIAGMDHVRLLPASAEHDWALQPEALKAAIEADVAAGLIPCFVMASVGTTSSCAVDPVAQLAAAAAGSGAWFHVDAAYAGSAALLPEHRHHFAGLGAVDSYSFNPHKWLLTNFDCCCMWVADSGPLKEALSLTPVFLRAAAGNSLDYKDWQIPLGRKFRSLKLYFLLRMYGAEKLRSYLRHHIALAGAFAQQVAADPRFELAAPQRFGLVCFRLRGVPREVNAALLAALNASGRLFLIHTELGGAYTLRLAVGAATSQLEHVQAAWAAVSAAADQVLAEHGVAAAAAAAAGKEVAAAGAGSGAGARS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJW7</accession>
    <name>A0A835WJW7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Diphthine--ammonia ligase</fullName>
            <ecNumber evidence="2">6.3.1.14</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Diphthamide synthase</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="8">Diphthamide synthetase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_005703</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>diphthine-[translation elongation factor 2] + NH4(+) + ATP = diphthamide-[translation elongation factor 2] + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:19753"/>
            <dbReference type="Rhea" id="RHEA-COMP:10172"/>
            <dbReference type="Rhea" id="RHEA-COMP:10174"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16692"/>
            <dbReference type="ChEBI" id="CHEBI:28938"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:82696"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="6.3.1.14"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1">Protein modification; peptidyl-diphthamide biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="6.3.1.14" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2448947.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="686384at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017178">
        <property type="term" value="F:diphthine-ammonia ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017183">
        <property type="term" value="P:protein histidyl modification to diphthamide"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd01994">
        <property type="entry name" value="AANH_PF0828-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.620:FF:000145">
        <property type="entry name" value="ATP-binding domain containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.90.1490.10:FF:000001">
        <property type="entry name" value="Diphthine--ammonia ligase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.620">
        <property type="entry name" value="HUPs"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.1490.10">
        <property type="entry name" value="putative n-type atp pyrophosphatase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1330.40">
        <property type="entry name" value="RutC-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002761">
        <property type="entry name" value="Diphthami_syn_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030662">
        <property type="entry name" value="DPH6/MJ0570"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014729">
        <property type="entry name" value="Rossmann-like_a/b/a_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035959">
        <property type="entry name" value="RutC-like_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00290">
        <property type="entry name" value="MJ0570_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196:SF2">
        <property type="entry name" value="DIPHTHINE--AMMONIA LIGASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12196">
        <property type="entry name" value="DOMAIN OF UNKNOWN FUNCTION 71 DUF71 -CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01902">
        <property type="entry name" value="Diphthami_syn_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52402">
        <property type="entry name" value="Adenine nucleotide alpha hydrolases-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55298">
        <property type="entry name" value="YjgF-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0436">Ligase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
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        <location>
            <begin position="24"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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            <end position="363"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
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            <end position="706"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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    </feature>
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    </feature>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
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            <end position="1791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
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            <end position="2136"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
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    </feature>
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        <location>
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            <end position="790"/>
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    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="10">
        <location>
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            <end position="809"/>
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    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="10">
        <location>
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<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WL97</accession>
    <name>A0A835WL97_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">CSC1/OSCA1-like cytosolic domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005607</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WL97"/>
    <dbReference type="OrthoDB" id="297739at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005227">
        <property type="term" value="F:calcium-activated cation channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045122">
        <property type="entry name" value="Csc1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018:SF135">
        <property type="entry name" value="CSC1_OSCA1-LIKE 7TM REGION DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13018">
        <property type="entry name" value="PROBABLE MEMBRANE PROTEIN DUF221-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="67"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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    </feature>
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            <end position="435"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
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    </feature>
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    </feature>
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        <location>
            <begin position="796"/>
            <end position="821"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="849" mass="95628" checksum="49D8EEEC120BE5DD" modified="2021-09-29" version="1">MGAPDRNDTLNVDTLDTKNARKRLVSTAKENARHEDEKLLSDGLDVGTSYNKVAAYRGVGLGLYYKLLPWLIWMMLWMFLCSIPYLIVINTSVFTDEAHKDDNNFGVKMYDSFELASFTFAAIVDDDTDGGLLKYMNTNIADTWKGPMSKGAFLTWISLVDAGATVVLTGVVVFLFFKVDRWLARVDDRTREVADYSVIVGGLPPDVTATEIGDYFQQHFSEDPTRDKVMDVVLVKNLGVILRACKKVHKYEELKEFVDNIKVAAQEKAAYAANSAKNLTGKAAQAAAAAVAATTAEGVEDGERPTGNVLSRKMSKKMSQAESKIANQRSLIDSRIEAGMSTKAAFVTFNTEKMRINVCKALPSGWWSSWFIRKQYRFPHAGRTLRIWAEHAASPDDYRFENLSVRPRINMLIQLLTAFFMFVFIVICAAFITWLTDKSNTESRNLLWDSDKIAAPLNTYYNSTYVRKVVSAGRRMLGIVDLAPYQNLESMCRDASLYSNCSALVNSNVNRELTGAQFNMYFEKEWTFGNPNATTKADIANSKITRLLFERPVRKYLSECSQTPNATTCYIGANLVDVSGCLPCYCYGLSLINTQAASTDFINHVSDTCKQYWQPFDLQRDGLKVAISFVIAIINAILVTTLRMCKFYVERHWTTTRTELSFAVWTYIVKMVNSVAVLLIVNCSTLSKLQSQAVSSKATGSNKWLSNLILNGSYSDFTPEWYETVGFSILILMMINVTSPFVRTIVEYSVKFAMRIRLLFCHCGGLAAPEAYNIAWRTPQFTLEQRTADILFNLTLALMFGSGMPLCYLICAVYLFTTFWWDRVSLLSLDQPSQRYSRVLPYVILSAEH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WPA5</accession>
    <name>A0A835WPA5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_003965</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451362.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WPA5"/>
    <dbReference type="OrthoDB" id="10249535at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005847">
        <property type="term" value="C:mRNA cleavage and polyadenylation specificity factor complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004534">
        <property type="term" value="F:5'-3' RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004521">
        <property type="term" value="F:RNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006398">
        <property type="term" value="P:mRNA 3'-end processing by stem-loop binding and cleavage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16292">
        <property type="entry name" value="CPSF3-like_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10890">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022712">
        <property type="entry name" value="Beta_Casp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021718">
        <property type="entry name" value="CPSF73-100_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050698">
        <property type="entry name" value="MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011108">
        <property type="entry name" value="RMMBL"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11203:SF11">
        <property type="entry name" value="CLEAVAGE AND POLYADENYLATION SPECIFICITY FACTOR SUBUNIT 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10996">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF11718">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16661">
        <property type="entry name" value="Lactamase_B_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07521">
        <property type="entry name" value="RMMBL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01027">
        <property type="entry name" value="Beta-Casp"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01098">
        <property type="entry name" value="CPSF73-100_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0540">Nuclease</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="6">
        <location>
            <begin position="5"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="Beta-Casp" evidence="7">
        <location>
            <begin position="209"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="domain" description="Pre-mRNA 3'-end-processing endonuclease polyadenylation factor C-term" evidence="8">
        <location>
            <begin position="442"/>
            <end position="673"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM01027"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01098"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2451362.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="680" mass="73501" checksum="37A9766B590D88DF" modified="2021-09-29" version="1">MFDCGIHPAFKGMDSLPLLDEVDIDTVDVALITHFHLDHCAAVPYLLRKTRFKGRIFMTHPTKAIYYSLLRDLAKGSKHSSEEALFNEEDLEASMQRIEVVDFYQTIEVAGMQITPYRAGHVLGAAMFLVEVAGCRCLYTGDYSRLPDRHLPAADIPPVKPHIVIVESTYGTSRHLPRLQREQLLLDTIRATINRGGRVLMPVVALGRAQELLLLLDEYWEAHKSELSGIPIYQASSMMSKALGVYQTYVESLNDDIKRVFHDRNPFKFRHVQTLKNPAHFISDYSGPCVIMATPSGLQSGASRDFFEAWCEDSRNTCIICDFAVQGTLAKEILGGPNSITTREGRRVPLRISVHNISFSAHADYDQTSGFLDAVRPPHVVLVHGEYGEMRKLAKALKDGAKAAGVAREVYTPLLAQTVAVEHKPDRSVRLQGRLGEKPPREGGAVRGVLVRQGGGFATQLLAPADLPRYTKLLKGAVTQRQAISVDRPFSAIRLALEVMFEGVEGAGTLPVATAPDAEGGKGGESLAVVVGELVTVRYVPADDASGGVAHVVLEWEGGRQGDMVADAVVAVVLQTIGEPPEATSAESAMLAARAAGDEAAAAAAELHLIGALLRSQFGPAAVDEAGGRVVLEVDGVAATVDYRAGKVVCAEAGLKGRIEKSLDRLAAAIRPAPLDRPHD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRE2</accession>
    <name>A0A835WRE2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SRCR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_003080</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452044.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRE2"/>
    <dbReference type="OrthoDB" id="539570at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005884">
        <property type="term" value="C:actin filament"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030041">
        <property type="term" value="P:actin filament polymerization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051412">
        <property type="entry name" value="Formin_Homology_Diaphanous_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001190">
        <property type="entry name" value="SRCR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45691:SF6">
        <property type="entry name" value="PROTEIN DIAPHANOUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50287">
        <property type="entry name" value="SRCR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032923300" description="SRCR domain-containing protein" evidence="2">
        <location>
            <begin position="31"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="3">
        <location>
            <begin position="764"/>
            <end position="846"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="32"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="195"/>
            <end position="214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="274"/>
            <end position="295"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="439"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="851"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="34"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="203"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="274"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="445"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="851"/>
            <end position="879"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2452044.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="911" mass="94541" checksum="132239BC19E61FE5" modified="2021-09-29" version="1">MHREYAFGRTRWLLLALVFALSALPAHVSAATDAPPPDAGIPPSDDPPPVARRGASPPPPLHPPPPPAAPPPPPPSPLLPPPPPQPRAPRAPPSPRPPTPPSAVYTISGERLKLYPYAYTRNATYLNGTLRAFTNATGGLGYLFGFVAPSNQSGAAFSAGAPSAMPVCLPGFDNTAAALACRAAGLAGGRHVNTTSTPANATSGGGSGGGSGTSYQEVSYVPSRQVGAFRLLRQVSCPAWATSLAFCRAELVDWAGPRECASLTAVVCDTVASPPPPATPEVDAPPPGDTPTDPANWDLDIVVGWTVGGTDYELGYDHSPVRGGLYGGNNLVSQTSWERVYWPRGSTPDAATYHVCVRWFTGSRRLFLGLEMEVAVEGLQEYSEIATWGTWLTRNTACTPDANGYIGSYTYTPAPAAGGGSSSSSSSSGAAPALEFRLSWGPESSPAPPPLEPSPPTPPPPPPPPPPPPPVVPQGMEPVCLDSTYAAGTTLAKYDAVDGGGAASSSRESCLAACFRHRPSGSCQFIVYDENQGMCYLKSNFLRVNGTTEEGDVNSADEFGDSGVNADTSVCFAPPEPKVLSEDGVPLASRNNYACSSGWDLRGRRLGYGNLFRNEEECAAACDLNAQCQYYEYEPDLHGNPCSLMYDVLAGFPKPVTTYGTPAPVCVKALRPDAPRRLELPVLSRLSMLLAAVVGPDAADGAWPAVAGYNTGGGAAVVYAWLVSEDSGLGRVGTSTNYKRKLYDPSTGATGVAAVPLCADGGSSSGWGDAQAARLCRDVGYHGGYAYPWPAAGEAAAAAAVGPLRGGVVSKLACPGVDGDDVWLLQCRAVVEEDRGCDRVAAALCLPAPPPPPSPPALPSPPPYVAPPPPPPPPQPPRPKSVSPTGGRGSTGKGRQRESVTGMAKKKRRQC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUJ1</accession>
    <name>A0A835WUJ1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Polymerase nucleotidyl transferase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_001748</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453528.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUJ1"/>
    <dbReference type="OrthoDB" id="549996at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001730">
        <property type="term" value="F:2'-5'-oligoadenylate synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11258">
        <property type="entry name" value="2-5 OLIGOADENYLATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11258:SF11">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50152">
        <property type="entry name" value="25A_SYNTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="427"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="415"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2453528.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="460" mass="51094" checksum="142823EE349D0DDD" modified="2021-09-29" version="1">MPADDDELKCCYLDLKRDKNKEYVRYFNGHVLPLTLRGVSYNVPKAVTDTVVRRLHECPDLQVGRVHIGGSYGRATLVRGAFDVDLSVFVNEYKGRELHDLKEWGGEAGERLQRDMQKHVARWLRQSNASEQVVEVEYGTHYKHCINVKVDGVEVDIKLVPSVVPGSQAKDLGKAQRDALMQTLLDTPPEKRCADPVREAALAEALTAFVKNTPERVKRVVRLIKCCVLLEALVLTVAGWEENPGAREAEVRCFQGALNLMQFAVAEGVIVDACDESGVWGHSQDEGWSCEHVWTGDPFVMLHPIDFTCNLGKAQPGRTVDWKALAWEAHELERVMREESMWALLHDSSLTPALKAMAAPDQEDKEEYKEEDRECVCMGSASAWRSGPRTIFTRRAHPEERLRSGHSSGPRGVSGYEPATMSMSASWLVPAAAAVVAGLALMFGSRMLGSGSGPSGRERR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUK9</accession>
    <name>A0A835WUK9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">HAUS augmin-like complex subunit 6 N-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_001303</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454272.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUK9"/>
    <dbReference type="OrthoDB" id="550856at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070652">
        <property type="term" value="C:HAUS complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990498">
        <property type="term" value="C:mitotic spindle microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051225">
        <property type="term" value="P:spindle assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026797">
        <property type="entry name" value="HAUS_6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR028163">
        <property type="entry name" value="HAUS_6_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16151">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR16151:SF2">
        <property type="entry name" value="HAUS AUGMIN-LIKE COMPLEX SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14661">
        <property type="entry name" value="HAUS6_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="HAUS augmin-like complex subunit 6 N-terminal" evidence="2">
        <location>
            <begin position="23"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="399"/>
            <end position="419"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="519"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="948"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="360"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="399"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="760"/>
            <end position="769"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="770"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="948"/>
            <end position="975"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF14661"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2454272.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1206" mass="116285" checksum="8337064A0F9A0534" modified="2021-09-29" version="1">MQRPGAPSSTKLEVATADESFLYRNFCILGLHTALRQEGFELSPTCFRRSNNKALEHVLYRLFIIIEGKQRAAKEFKDRWPVLDKVQQTPFYQKIGDWTKELKDAGRLDPSVILPVSALKTNTSNRLTSLLLELSTLALQQELEASGPPGQGGAAAVQQQFGSSHPVEELLPLELRLGHAVARSRMAAAAFLQTCAAGAAACEALEAGAAGFKRSYYQLQASIRQHEAAKAEIRARMDASSALPWQQQQQHTPQQNRAGTSTGGGGGSPGVQRSPAALAAAEAAAAAAAAGRSPLAAGRPSGGGGGAAAPDAEAAAAAAAAAAAAAARQAAQLRRLAAMLCGLDGHLADHVELSRALMTERTTGEGAQQQQQPGQEQLAQGAVGEAAQRDAAAAASAAAAAAAAPSAPPQQQQQQQQLVLHPHQIDGAELRAIAARAAAGLLGSAASAAAAASSSPSSAFPGGDQQQQPSGGASRSTPAASGPMPLAPGPDNVLQAVQLFASMLGTLSPHVSQLAMAGEAAGPPPLLQPPSQPSSHAAHVAHQLQVHTAASRQMAAQAAALKQQAAAYEPTLEALRARCPRQPVAPPPPPRTRPAAAAAAAAHYDYDFDDSLLSAAAAAAAGGIATAAAATPGLGPRQQGQGRGQGSSDGDLFGGAAAAAAARGAGLGLELELGLGLDGGTLMLGLPPSHLPGGASVSNWAAAAAAAAAQPPGREGRAAASLSEAGAGGAGFGAVASSPMGRAKSQSAGGLGGVSAGGGAGGGGGGGAATGASTDLLSPQRSHLQHQHSQRAAASPSSSAISGEVAALQARLQKLTGGGGIGVGAASPTSAPQAKAAAQAASHSPTTFAAMAAAVAAFRASSGMAAAAAPAAAESAPAGSTASLSGVPAAVASAFGECASGDAFAAGGGFGGAGGFGGFGGAGGSDGGAGGLEESDAALAAAAEAAAAAVQHHVQHHPQQPAAEPGPAAAAASGAQHPANQGGDDGSRDDGGGGTAAAASRAALAALLATDSGDDDVLMADMDVDFGSGMAAGTVPATSFFSPAKVLAAVGAGAGAGGGSTAAGKLAFWGDDAVASPAAAAGGGGTKAALGGLLLSPRSRGIDQVLGSMAGAASDTAAAAFATAAVAGRGVIGGSSFATALDAAAAVAAAQPQLASHPSSMGFGTTSGGGLSSVTSATSGGSGPVVLGADILALKARMAAMQQQAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUL3</accession>
    <name>A0A835WUL3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Heterokaryon incompatibility domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_002352</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453016.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="513151at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198">
        <property type="entry name" value="ANKYRIN REPEAT AND PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24198:SF165">
        <property type="entry name" value="ANKYRIN REPEAT-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00023">
        <property type="entry name" value="Ank"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01415">
        <property type="entry name" value="ANKYRIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="25"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="15"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2 3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="601"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="636"/>
            <end position="668"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="669"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="803"/>
            <end position="835"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="836"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="869"/>
            <end position="901"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="902"/>
            <end position="934"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="936"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="970"/>
            <end position="992"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1039"/>
            <end position="1071"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1073"/>
            <end position="1105"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1106"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1208"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1240"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1275"/>
            <end position="1307"/>
        </location>
    </feature>
    <feature type="repeat" description="ANK" evidence="3">
        <location>
            <begin position="1308"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="38"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="38"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="82"/>
            <end position="107"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2453016.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1590" mass="169918" checksum="E593ACA1F46E63E7" modified="2021-09-29" version="1">MGCGASTAQPARLSPEDQAKLQEQLEKQAALAKQLEEDRKQWEAERKRLEEERTKLENERRLQEEAAAAKKKAEEEAAAAVRRAEEEAAAKIRAEQEAARKKAEAEAAAKKRAEEEAAAKKKAEEEAAAKKKAEEEAAAAAAEAERLRWEAEAKDATSGDPALAMDFPSANLHLAELQEFVLELQDQLPLPVRAAPMRLLHIDAVLRWDGGIRVFEEVKPEEAITVPYTDVTEEQWADTAVLSWRWGNPKPSAYVEGFSPMSGLQLAEMRRLLHRLRAAGFKLVWIDWSCVPQYRESPMTEVLRSKLFYARARTMVVLPVFMTFEGLPENSAGVVRVLLGKAARALKRRAKEEGRPNSAEAGAALSRILESEVVAGREYFCRAWTLAERMARHGRSEPLRQWLSCETWLGMLVDSLIHANEDRSTSKIYQKILGPEAATLLDALVEPLGEAVATGSPHDENMVEQVATLFEAAAGVWKDSLNLAEAPSKSWLAAYLNEVHTGIYQAWSRPDLLWAVYSYFCFKPLDQGTDEGVMAALQALVKVVGGDEMRTSFLATKMGLGHMITLRPLDRRLHTAVADNKAAEVKELLAAGAFVEALDAAGRTPLLMAVVAGHADTVRVLLDGGASRQACMSEEEKDSALHVAAARGDARVAELLVEGGADTAARDAAGCTPLTVAAREGHLEVVQLLLRASGGKDVETKDYAGNTPLHHAAIHDEVAAALTAAGASKAARNAAGQTPADRLKALETRRAAGIPPRPPTSDAERVLLEECSKPQTESRAVAAAVKKLLLTDATVNANAQNEGGETPLHLTARNGHKDAFRVLTLCGALRNVRTKADNTPLHCAAVGGHVGIVELLLAEAVDMEAVNKAGDTPLLLAALEGKVDCVRLLLKSLAAKDVVNKDGMTALHCAALSGSAETIRLLLSAGLDMEARTKTSSSTPLHLAAGAEASEAVVRALVGAQADLRARDEDDYTPLQVAVRSGNVEALRALLEAAPPELQRERTKKGGHTLLHLAGAADSPNTLEELVTAGFGLEDMNELGDTPLGHAAAMGKTEAVNKLVKLGAQKEAKRKAGGYTPLHLSAYSNHKDTVAALLRLGADKESMSEAGQTPLLLAATGGAVEAIKVLIEAGANKEAMKPADGGTPLTCAVLAGKAEAVRALCAAKVNVQVQTKEGKGLLHVAAGVTANTAEIIECLVAAGCKLDSRDKEGDTPLHIAARSNPAAVTKLLKLGASITQTTKSGLQPIHVAAQEGCEGTVLALLSGGAHIDTPCPASNGVTPLHITVIQGHVALMNLLVAKGANKHAVIEGGNTAMHLAVANDDPDIIRALHKAGAYMPNKRNDDGLAPVHVAAQEGAAKAIPALHEIGEDMGLLTGKNEAIHLAVHEDNAEVMKALFKVRPECKERADGNGFTPHILAIRLGKVEAVRAICMDFLYFYFTSQLNTLKLALLGSTPAVVEMCMEIYPYDKTLKDSALHFLFENGLNLLHVAAQRKIEDNGAMVTWLVEKKGLGNLLFKVAEEHLSYASPKFLPLHFAAKCGNASTVRALVRLARERGVNNINQSSNYEGTPLDLAIKYKNEEAKAALKALGAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUL8</accession>
    <name>A0A835WUL8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBM20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_001056</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUL8"/>
    <dbReference type="OrthoDB" id="533354at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05467">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:003359">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15048">
        <property type="entry name" value="STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15048:SF0">
        <property type="entry name" value="STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="3">
        <location>
            <begin position="87"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="3">
        <location>
            <begin position="276"/>
            <end position="388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="211"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="406"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2454015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="599" mass="63665" checksum="E9071A38D28D373F" modified="2021-09-29" version="1">MAAAMKCQAPSRAQVQQRQRSHVSMSGADAGWQTARDVTRASAVSRGATAAAGSLKASTPAAASTITAARGAALVARYATSTASTLPLDGPALTVRTRVVVPYHPTSHGQQLVLVGSCEELGNWDPKKGVKFTWCEGHSHEAELELPVHTNVSCKLVVLGEHDSNTWEPEANRELLLAPASLASRAAGYTMIMHWGFPDCVQVMANSLRRGTGVSPGSSGRASPGLNGSSGGVMGNPLIAGMKKALEAASSRERFSSVISGSASWEDEFGADDEPVLTQCQVTVLMPKNGPKLKPEQSLVLVGSSAALGRWDPANGLPLERAGEDSPMWTSQAELPLGDSLQAKVVVVDGVSGKAEIWEPCENRSLARYRGSKPVMVTAYYGVAPTHSLEVDRLSAAAAAGSPQVVALLRQQLANTSSQLDGLRRERDDARKAVADKEQAMKSLEGKANNAAPGRFEMVHLAEQLQTTRKLYEVTKKEAMELGGTVGVTRQLCDAAKKELAGLSKQLIAAQKAYEALAPQVERMEKQLASTNRAFDATKPELAALEAQLERARGLFDRTLSKIEAAKSLASGSSATASGDYDLTRRRVDSRVREMQFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUM0</accession>
    <name>A0A835WUM0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">WSC domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_001318</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454287.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUM0"/>
    <dbReference type="OrthoDB" id="203237at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="168"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="466"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="839"/>
            <end position="868"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="964"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1109"/>
            <end position="1178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="168"/>
            <end position="281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="493"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="846"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="965"/>
            <end position="994"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1109"/>
            <end position="1130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1138"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1178"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2454287.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1178" mass="119680" checksum="92B1E1D48A8C6CC5" modified="2021-09-29" version="1">MPLPPSPAPPSPQPPLPLPPSPAPPSPQPPLPLPPSPAPPSPIPPSPPSPVPPSPSPTAAPGSDVGIEMTFGGVSLPDVNQIQLANQSCVELVNSTGAFKCVNNKLVAGSIIAGYVLTAPPGTPLNVFYSSIQTAMTTDPASLFSASFFTSFGISSVNGSVLPGAALPPSPPAPLPPPSPPTPPPPSPPPPPPPPPSPPPPALSPSPLPPSPAPPPRMPPSPQPPSPVPPSPAPLTPPPSPQPPAPPPLTPPPSPASRPPSPSPPPPPSPFPPPSPPPPPGQFISGYAVTYTPTFCVGLASDSGFDVFDPTSLDQFGRITAITYVYDAAIPGVVVAVKLTYGTGANTHTDVVAGSVYDPSSPTLSESSVSLVSPSGSALQTLSVCCTSTSSVAQLAVGFADGTAASTGLCPAGARRRVLLQAGVSPSGGSAAVPTGAMVGGVRGGRGASVNSIGFALAVKTSYPPPRTVPFPPSPAPPSPEPSPPPGRRRPPPPDAPSPPPPPPPSPPSPPQPAAPGTPARPPLPPRPPSPPPPPPFLPNVPPPPPPPVGTPAAPASPPPPPLPTTASVQVAFQAAVKVDYVQIVAGVPPQVPNTVPASTLVLLGPAVPIVRNTLADPVIASTIYGRGRVAAFGGEKMITSCCKPKGKPTPSDPSLDKIIVNTADWAAWYGKKVGKAIIRVSDTRYMPMAKYVVKQLPESFDNLKSAKIKTYYLSLKAFLKNGHKACDVYVIGSYDVQYLQPRVSQFLQEFVSLGKGLLVVGPDVMPSIFYPGTSAATPVPSPAASRRSLLLQRAAALLLGEASAEHDVMDADVSSLDGNEADEEMRLQLNSQMAAGGLARRRELQQQSGSSTSSSAPGDPLFNSTSIPVNQVSGPMGLVFSGYVSDPGGNLTVTSPSELQNAELAASQYVDYLQGRMSLTVPELSLAVSTITKARASVPRSTPGASRFWDLSDEATVLSATAPALPPLFGDPPPPPRLRPPPPQLPPRPPPPSFLPPSTAYVGCFFEVASRRALNTTLLTGAGISVDRCLGIATNTSNPSVAGTTFMGLQRTACFGGRELSSSFVAAQLAEAACPVPCPAAANQKCGGNANATGLPVSVYRILSAAPPPSLPSPPSPAIGAPPPSPAPAPALAGTRPPSPAPPVPQPRQQPPSPAPRPPVRPPPPGAKKKKAVRLAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUM2</accession>
    <name>A0A835WUM2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_001792</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="546328at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051002">
        <property type="entry name" value="UBA_autophagy_assoc_protein"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31915">
        <property type="entry name" value="SKICH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31915:SF6">
        <property type="entry name" value="SKICH DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="460"/>
            <end position="488"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="561"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="988"/>
            <end position="1027"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1122"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1317"/>
            <end position="1337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1358"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="5"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="105"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="189"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="267"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="359"/>
            <end position="437"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="653"/>
            <end position="725"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="773"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1042"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1189"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1420"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1141"/>
            <end position="1162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1358"/>
            <end position="1367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1394"/>
            <end position="1405"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2453573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1481" mass="152894" checksum="D5D95884F1640AEF" modified="2021-09-29" version="1">MTDAVGAMEQSLAAKAAKLAEAEAKLAEAAAQNAKLSAALEAAEAERADLVAKLAVVTSASMAPSPRDLPAAATSPSGAAAVSDPALLGVQDKIIKLTREQAAERQQVLTSLKEEQRRLAAIRKEITETERANAELKKSLGRTDLKKLREQKEALAAQAAEAEHLAAHVAALGATANRLAALQAEKVRLEPLGAEVAGLEEQLRELRQLEATRNALQAEAAGLQPAAVVTERLRKQVTGLRADAAAAEALQEQVAALSPVAEQLPGLKALYAKLQASAAEVRQLEKQLEQRDKTEALRLQLQGQLDELHAKVSDIEDLKKRVEAAQLSAGEVQQLEARFAALQSVAARLPVLRTQHDKLAAQCAEVADLELALADLKQQVALRNALQQQINILAPKAAGAEALRAALRDIEAQVASAEDLEKQLQLMRTQAADRRREGASQFVEAVSNLGLVPAADAAAAADAGEGAEGGEGAEDGLPPMPERTSHAGVVPAGGLAFRSHPAAFRSTSAHHTVGGAARDNSQFSEALSSLGLELQRGGPGGVSFSGGGATAAAAAAATAGAGHTPAGSVQPTPRGMVSSGGPPPAAAVAAAAAAGAAAAAAAAQLAEGERKERLAALEKQMRAEAEEAYAKEADELRVRASELAAAAVPPAEVAALRAEVAALESAANEALELQKQVAEMKLLASQRQELQRGMEESLQSQLALLEAQAREAEQLERQVQQRSDVVARKHELEMQLTELEASSAEIYLLDQLVAGRQETIARRPELEAEAARLQPEAEAAESLKQRLEQLQAAAAERPELELKAAELGAAAEEVEALKSQVSAMEASVAERAALDARLAELGTQVAQIAEVRAQLAEAQALVAQHDEVAAELGRLAGPAAEAARLKARLAELRELVASEAQLEADIEAAEIDVARVRTLEVIVNQLRTEISKGPLLQDELRGLNETAERLQHAEEVQVRADRDAARMRVLELESILAELEKQMSQQQQPAAAQVAATKSRSPFEQAAGSVPLAGGGRTSSGGMSDGEEGEMLAAVQSHIARGQQLMDVKSSLQQELEELQAVEADVARLQTAIRALAPLVEQRAALQAELEEMQRATLAGALGLAGSSAGAAAAGAASTSTLAPAEPMLPPHAPHAPSSSSGGGSFDGPLGRGAAAGMGGGARLEPQAPLPSDPNAAALAAALGDADAIAAVAQQRGALTAEVEALRAQVAEVAALREEREALRAVEAEVVALSNEIPHLAPYVELLPALRAEHARLKEALAEAERLQSDNESLSLQLNVMKALREAAAAGGAGATSTGGAGKAGASAGGAAAVAGSAVSTRTTGPGEEDSGAEERGAEWLQRQAAPAGPVEAEVGGAGLAGAASNGGAAGPDGDDDEPRTPTSQTKPGTGPLAATAAEDAEAAATLHVESQLRSVFGKMRDLEHSRQGLEEENEELRATIDDLRQQLEASAEAMQKLRGVAEALSMLRRGGAGAGAGAAY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVL2</accession>
    <name>A0A835WVL2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Nucleoside phosphorylase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_000948</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2455128.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVL2"/>
    <dbReference type="OrthoDB" id="1153057at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008930">
        <property type="term" value="F:methylthioadenosine nucleosidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019509">
        <property type="term" value="P:L-methionine salvage from methylthioadenosine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009116">
        <property type="term" value="P:nucleoside metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1580">
        <property type="entry name" value="Nucleoside phosphorylase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044580">
        <property type="entry name" value="MTAN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000845">
        <property type="entry name" value="Nucleoside_phosphorylase_d"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035994">
        <property type="entry name" value="Nucleoside_phosphorylase_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46994:SF1">
        <property type="entry name" value="5'-METHYLTHIOADENOSINE NUCLEOSIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46994">
        <property type="entry name" value="5'-METHYLTHIOADENOSINE/S-ADENOSYLHOMOCYSTEINE NUCLEOSIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01048">
        <property type="entry name" value="PNP_UDP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53167">
        <property type="entry name" value="Purine and uridine phosphorylases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nucleoside phosphorylase" evidence="1">
        <location>
            <begin position="1"/>
            <end position="218"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01048"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2455128.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="233" mass="24401" checksum="3AD40EC0BAF2AE41" modified="2021-09-29" version="1">MEAEAKPLIQTLELKEDVPAKIVGPAPCVTFSGEHQGLSVHVVWNGRCKDHGVDNVGTVPASLSTYLAVLAFKPDVVISAGTCGGFKAQGAAIGDVFLGTAVINHDRRIPLPSFDKYGLGHAQLLATPHLQAALGLKSGVVSSGNSLDYTDKCMEIMTAHGAALKEMEAAAIAWACALYKVPLMCVKAVTDIVDGDRPTAEEFLENLHSAAAALQSTLPKVLGYLAGKELAQL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WW07</accession>
    <name>A0A835WW07_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_000630</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WW07"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032295838" evidence="2">
        <location>
            <begin position="27"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2454795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="106" mass="11327" checksum="899312A699C18578" modified="2021-09-29" version="1">MTMAPKQTTLLLAVAALAALATCASAGYTQSPPRRSPPRMAGPQVYGPPMTNSWLKMPANGRFRVMQVADVHFQNGANTTCQDILPEQLPCSDLNSTALLTALIKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WWQ0</accession>
    <name>A0A835WWQ0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_002004</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453795.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WWQ0"/>
    <dbReference type="OrthoDB" id="553375at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="181"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="251"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="539"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="709"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="742"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="118"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="251"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="275"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="419"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="435"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="564"/>
            <end position="574"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="590"/>
            <end position="601"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="615"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="742"/>
            <end position="759"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2453795.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1198" mass="119897" checksum="7A00DCB156F6E75D" modified="2021-09-29" version="1">MSDLGLGGEGGQGEDEEGGDEGEAMLGLLAGLDARTLAAIPPALLHRLQQLEEERDELAGRLLESDAELSCLRANYQQLSQTHASNQTWLNQLMNQQMENLERRQRRQRALAAAAAARAAAAAGGSQPQVVSIAPMSGLLDSTALETGDFDFTGEVDSVLLDQEDLAAIAASAAAAGVLGPSSGAGAAASGEGASLGTSPLKAPPSAKKLAAAPLAQVAAAVAVAATRGGADTGGAAPIDVMALAAEQPRGGAAAGASPPAKTKAWEAPRPSSEAAAKPVAAAVIEERPAPASKPAEAQTQTASSKPKEHGRKIRKEEAGSEADAAETAVVTSLASAEVESPAAKPEAIASRSANNEDAQGRVSADGKADAAAKRPSKVVAVTAERAARSEANSEETPVAKATAFEKSGRASSQGGAETARDAGSDRSVSRNEDAASSTRSGSAAASAKPKAKDAGAQAATASPAVTKAAASKLASGSGRIGGSGLPLVLALLVVVALGAGGAYVFLGGGLRTAPASSGGPTISMTSTTSDVIDAAAQTGGADGMVPPAMPAAQHAPDEAELSPSPPPAPPPPGTGASLLAEDADDDDTAPNTGAAAPDAAAPEEDEHIGFVDVYDSEDEYDDSGDGDDGAAAAAAADAEDLNSGEHVRFATLVNAPAALTPGQYWCTDTTSCEGEEAGGGSDAAVRTRALPQPSPVWDLLRAGLAAAAEEEAAGGPGSATARPQPSCESLRALASSLSATDTELASAGKQPAATPACSAGGGAGAGECRPPPSKTTGSPYPMDARAELVKWGMAELEKRWRQLQRTLERLAGEGEAKDGVASPQLPAEPAVQAVASWALGHLLPVVAPMVRSVVDDDELPESLKRAHKAASDVARVCSESGPQLSIAALGRLEAQLNDMTNIALVHVDGGGAAAVEARLGDAAHCLAWIAPRAAAEACRLRCSPRGRLVGALGRLGIPRALLDGALTLGRSGLDERDGVWRHEQPPGEDAGIEDVEAWLRSTQHLADWVAAALAAKEGDGSSSETGCGAWQTLVAAIGATLRGSTAVSDAVAQAAEVGDWRRLQLELAAEAEAAQRVPSHVLEAVAEAARRAFAQEGLSDCSGCEEAGDGEGKDAAEEAGAPGPACRAGLRSLGAEVRAVQATAAGAGAVQQGLAAAVRRIRADVMDLMAAVAVVRARCLVAAEGVLEYRKAGLAAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WX16</accession>
    <name>A0A835WX16_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_000579</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454743.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="543841at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000048">
        <property type="entry name" value="IQ_motif_EF-hand-BS"/>
    </dbReference>
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</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-12-14" version="3" xmlns="https://uniprot.org/uniprot">
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            <taxon>Chlorophyceae</taxon>
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            <title>Comparative genomics of Chlamydomonas.</title>
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                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
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            <strain evidence="1">CCAP 11/173</strain>
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        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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</entry>
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    <name>A0A835WZ43_9CHLO</name>
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        <recommendedName>
            <fullName evidence="4">BAG domain-containing protein</fullName>
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            <title>Comparative genomics of Chlamydomonas.</title>
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                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
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        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
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        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
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            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2454920.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="806" mass="81736" checksum="58C0C6F47CA2A736" modified="2021-09-29" version="1">MDLHEDPYAAAAAAAAARAARKPAASAPRPATASPAPSEASGYVLVPDGMGGYRLARPAACARTPASATPVASSAARPSARQPVVASEDEDDDGDVMDAVAAARARRLQKEQAAAALAAQQQQRRAAAAARAASPLIPALYHGEEEDDDEQENSEDDMHDVASVRSLQQLQQQQQAQRQQRQAQQQQQQPKTALYYDPTTGRYYRAPVQPEPVSKPAAKPAAVSTSHPAASTASQPRSIHVSQAQQPSERVPVTKAAPSHGTGTTTGATGRSSMQRQGSNALVTRPAMEVSLSRGPSANLPADPDLKLDSNGTGAAGAARTPSRSAPMLKSQAARTIQRWFRGWRLWRHRASLKALVKAAGELRQASAKFYEFMAATEAHITCRQAAEVNELAMRVIFKLDSLEGMPAEFRALRKHLVGRAMRLQDEVQGAYAKSAARPENGAAISADADTAKAAPATAAAATKASAAPATAPSCSSTGAAEQFRTPLPSPRAHPIQAQSTNDTVMSDPAGGAAAAAAEAAAAEPADALMEDAEEGGYATANDASASEASADDLAATVKQAGQTGRAGARGVHTGASSSAPGGGKGAVQRPSSTAAASASAAPAAAGVAASTVAAAAMKAATKGHGSDHENLTSSAPLSSQQQYNASRSASARPGASNSGATAAAAASNNHTNTNNPSSSSLPSPTAHKSKKAKLQGLRVGRVGSNGSMRRQNSREQKKQQKLVEEAAAAAAAAAEAAKASGAMSGGDGGGGGGGNGSKAAAATDTSGLSEHLQRLHKALLALQPQGKKKKDRAGGGSHGRKGHGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WZ66</accession>
    <name>A0A835WZ66_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Ion transport domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_000777</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="537858at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034703">
        <property type="term" value="C:cation channel complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070679">
        <property type="term" value="F:inositol 1,4,5 trisphosphate binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015279">
        <property type="term" value="F:store-operated calcium channel activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051480">
        <property type="term" value="P:regulation of cytosolic calcium ion concentration"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.70">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005821">
        <property type="entry name" value="Ion_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002153">
        <property type="entry name" value="TRPC_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10117">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL CHANNEL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10117:SF54">
        <property type="entry name" value="TRANSIENT RECEPTOR POTENTIAL-GAMMA PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00520">
        <property type="entry name" value="Ion_trans"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0407">Ion channel</keyword>
    <keyword evidence="5" id="KW-0406">Ion transport</keyword>
    <keyword evidence="6 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="546"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="580"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="683"/>
            <end position="704"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="724"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="783"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="904"/>
            <end position="926"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="1201"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="domain" description="Ion transport" evidence="10">
        <location>
            <begin position="591"/>
            <end position="820"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="353"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="390"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="458"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="957"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1055"/>
            <end position="1123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1259"/>
            <end position="1291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="463"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1107"/>
            <end position="1121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1262"/>
            <end position="1291"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023303"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF00520"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2454950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1400" mass="151344" checksum="F0B12816DDEB2898" modified="2021-09-29" version="1">MKAEDYLQVQFSGECEVYVLLVNERAAVPAWVESKFAKVSESRMALKLDWHLPFHIKMMALMSQKLQICTGAHLNVWRGKDKCAPGQSYTFGGNEGRDTLLDYSYIFAWRPLDAAARTRADLGGGTGLTTHVKRGAEESLRLLQHHQAELEVQAVGDELEAFRGSFEKYTWHRGIVLEEGGGAAEQLRRLRPWYVTADGTLLAAACAAKTVSLKLMLLLVRLGAELDEVAARYLLNKVATSAPEALQVAAGFRDLRHLLLHYCYSRRRPVSSTLALAKVLDQVASERKAKYREYTELAATLRQLAMALVEKLDTLEAAASGGALRAAATTSAASGGALRAAAIAAMPSTAAAGASSTEMGEVRRQPSIGSDDENALVNLGPEAREDAATMPAAAGCRPGGEASSCGDGDAGPADVAYAEDDAAAARRRSAMAAGGGCSGGSAQVASLDDVLILPQHTQVVPPGVGGQQQQGGGGPTLPGSLSDVSPLDVACETKEVDFVSTSVVQGYLQRWWVGVDYTATALQDYGKMISYFDHNMTLRILQNGGFVGGLGMLAVRYFSYLVHYMLFCSRPFYDSPRGRWAFRLMCEAFFLYIFHSVQLAEHQTFMWQHAALALHVASMIVDELQELMAFYEGRPVVYFQDGFNIIEGVAMLLLVASGGCKATTFVLSNDDAYLGELQTASDFLFNTASIFVWARLLQFMIPLYDGMGSLLMVISKMTSEVLKFALPGVVIMLGVAFTLFATYRGRDIPGMDSFWEVMLALFRTFLGETMFDTLSEETSTLYVVYGTIVIVLYAVAATVVLANLLIALISSHFEPERAESQSRLQRADMVNSYNFMVRNQLLGAPFSLPLLLVTELLPSGLRPWAGDYGDGWGAYLVLPMDGLPMPPETRKERRYPKGSRELPYVIYLLTFYPAVMALTWAMWVALAPYCLAYFTLYGYRNWLEVLRPADLEEDQAAAGAGDGYDEASDRPVGGAGPPQVLKGLAGAVLGGGSGRLQGSVLMAADTSARRPASAAVRPLSGISNKVVPEHPTQLAKQQQQQYGNDVHHYAGMEEFAPSSSSSSSHMTAAAPAVLGSGPRPVVESRAEDPEASSAAHVVRPGSATLGGTRGLGATTRGGGGSRFSPMGVIRAGLAWFLLGLEPRRPGKRRGSGSGRRRRAQGKGAAAKWQQQAYQPWNHQERAASLAWLVLRTLAYITSRPLWLLLGLLLYVGGLGGLPVVLWGGVYQWLWRVAYYSHWVVRGWVEGWFPALDTSQPAVAASQQRAPAQAGKAGAPGNSSTHQDQPAAAAEQQPEDYGLDLAAFVGLQWARRLEQPPALSPADIRAAMRDAGLPEGDVALAVRGGGPGWKAHEQQANRREQVRRADEGLVQRLTEVMEARMRQVVRDALAEAGVTAARPQV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B0C0</accession>
    <name>A0A836B0C0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Peptidase M43 pregnancy-associated plasma-A domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009247</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M43B family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000030">
        <property type="protein sequence ID" value="KAG2444050.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B0C0"/>
    <dbReference type="OrthoDB" id="540960at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.390.10">
        <property type="entry name" value="Collagenase (Catalytic Domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024079">
        <property type="entry name" value="MetalloPept_cat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47466:SF1">
        <property type="entry name" value="METALLOPROTEASE MEP1 (AFU_ORTHOLOGUE AFUA_1G07730)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="273"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="371"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="380"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="400"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="427"/>
            <end position="459"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="460"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008721"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2444050.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="503" mass="55139" checksum="D6151EAA714B1B4A" modified="2021-09-29" version="1">MWANQGHAFITWDLMVPAGYNGPSLYYGGSRVLLHELFHHLGLLHPFGPGNDDDDAEGGSARSCSDDDYVSDTPGMLGSAYSSNFYSTAVAYCMERFWETYGGDWEATYARWSGGLGTPQADMNAWADSCPTKAGYDLLGNYMTYNTPVCFAALGHFTRGQAEMAHYVTAELNPIIYAWGQYYAAVSPSPPPQSPPPPEARIDPCNVTQRSCACKQSWDFYGDTYSSCSVLPGNEGLWCEVLDQTSCPDCAGNKNRTVPCVRKCSGTEWMCKKRGPRPPPPPPLPPSPPPTPPPPPPRAVPDKCKVTSNGCKCRNTWQYNGKYWSGCASPDGDKRLWCQVEPSCPDYGYDSYLFYCDRSLTLDSCRVQPVSISQTRSRADPPPAPPPPPANAISGSSSSQPPPPARKQPSSRLPPRPAVGVNTSRAPPRPRPPAQQPRPPAAQQPLPPRPAAQQPPPSPQNLRPPASQQPPANDRPPPRRRRLRQQESEQHGGRLSRQQQQQH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B0E2</accession>
    <name>A0A836B0E2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_009177</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000030">
        <property type="protein sequence ID" value="KAG2443976.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B0E2"/>
    <dbReference type="OrthoDB" id="439192at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="134"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="140"/>
            <end position="154"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2443976.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="225" mass="23251" checksum="6494E11E2C051068" modified="2021-09-29" version="1">MAGRKQQRTSTRRKAPKAGGDNTSQSQRVHIHINNAAAPRRPANTRTMQRELLLGPMGLRGLPYMAAPSTTIINQMPSDAYNARFATDALLQGLQSEVRALKSENMGLHDHIDQAWGQVAAAFKPPSYPSDSDFTSTAYGAGGSSSSGGSSGGGPPAPHRAPSVKMQDADSASGVPMPKMPPMLLIGPTAAAARHDATRPYTRAAAGAPTSGVYAAFTGCAGPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3I7</accession>
    <name>A0A836B3I7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_008205</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3I7"/>
    <dbReference type="OrthoDB" id="18487at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006212">
        <property type="entry name" value="Furin_repeat"/>
    </dbReference>
    <dbReference type="SMART" id="SM00261">
        <property type="entry name" value="FU"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2446631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="555" mass="60441" checksum="B51C580090297D3A" modified="2021-09-29" version="1">MPRSARIQSLARAFVAGTYLGSDGICRECGNPYNTGTACKTLAPMCSDNLNHYRKCFECQPLYWLDSDGQCHPCSNPNNTPDRCAVLSATQCSDGQNHYVECEACQPLFWPDQYGQCMPCTTPNNANCKDAAALLTTCTDDMNHSQQCSECKPGYYLAGNKQCYRCSQSYAGNCLDSAGTCYNDMNHEEQCKADMCKPNAVMNYQSLCKLCYSQPNCALSAWECLGDGSRYLKCATSNPSFYVEKATGVVRKCTAQDSCSANDESKACVTPAADKLYCAATNNAAKYVTQGVVNTCKPQPFCADGASEATCVAAEVWLGVQRCTSCQPGYKLNAGTGVCGCPPTAAGEPQWLDDWPPGNPEVCRPCTNPYNTPAAADPADLLLECTPMNHYRKARACRPTYWLDGSDGQCHSCSNPNNVDAACAELTTQCTAMNHYRVCALGKCRALYYMDQYQQCMRCDASYSTEAMGCAKPSTTECVGYNKAIACDECLPGFYRDSGLCSPCAITYNDRCADGYLMPSCVEYSRDVNRPRQCSKCNAGWQLDSNSLCTIMQST</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B706</accession>
    <name>A0A836B706_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">S1 motif domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_005514</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the bacterial ribosomal protein bS1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449360.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B706"/>
    <dbReference type="OrthoDB" id="331005at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050437">
        <property type="entry name" value="Ribos_protein_bS1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003029">
        <property type="entry name" value="S1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724">
        <property type="entry name" value="30S RIBOSOMAL PROTEIN S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10724:SF7">
        <property type="entry name" value="SMALL RIBOSOMAL SUBUNIT PROTEIN BS1C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00316">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50126">
        <property type="entry name" value="S1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="105"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="domain" description="S1 motif" evidence="5">
        <location>
            <begin position="324"/>
            <end position="402"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="54"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="289"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="435"/>
            <end position="478"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="293"/>
            <end position="304"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="439"/>
            <end position="451"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="467"/>
            <end position="478"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006767"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50126"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2449360.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="478" mass="49752" checksum="CFF23C05E03DE208" modified="2021-09-29" version="1">MSATRAPAAADGRTVDTERLAAAPSEAAMAAVAAAYAAAYAAYAGRGSPGSLVNEGGASGDASSESAAAAAGPAQERAAPAAASAAAAPAAVKPGSHSAAAYTVGQVVTATVKHVGPRDGRQLACVILRVMTGHGDTDTDAASGSGTAVMGYLHTGTITHLPVERPEAIFKPGDVVRALVTAISKCGQRLTLSTKWLEKESGDMLRDPQAVYAGAEAAAAAWLARRLEAQADKQAAEEEKEAARKAKKVAKLLAKAQAQQTRVQQQQQQQQQQQQQQQQQQQQQQQAAQVQEQAEKQPLGHEEEAGAQAHGAPPTAASDELEIGEVVWARVVDVSAKRGGAVRLELLQGPHGPPGTGRAFMSAGAISHWAVEYPDSVFKEGDVVRALVVSAARNGDCQISTKHLEAAPGDMLRDRQAVYAGAEAAAAAWLAATEEKKERRQARREVKRARRQAQAGQGHNAVVHEEAEGEDEDEDNGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B7V9</accession>
    <name>A0A836B7V9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">MYND-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_004799</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450292.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40903">
        <property type="entry name" value="GLYCINE-RICH CELL WALL STRUCTURAL PROTEIN 1-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40903:SF1">
        <property type="entry name" value="HYPHALLY REGULATED CELL WALL PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032970935" description="MYND-type domain-containing protein" evidence="3">
        <location>
            <begin position="25"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="284"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="444"/>
            <end position="493"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="745"/>
            <end position="790"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="808"/>
            <end position="852"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1011"/>
            <end position="1040"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1211"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="507"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="73"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="468"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="767"/>
            <end position="778"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="824"/>
            <end position="836"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2450292.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1312" mass="132373" checksum="2159D2F6F6964B28" modified="2021-09-29" version="1">MGSPSASALRHRLVLAVVRSGVLSQLARVLTACPAGARQAWDSRLNDWCELSGHVADLVSSLACFAKEVEASSGGGKASGSGGGAGAGATGNHANGPGGSSAVSLAAELLAALQRSSVLEHISRAVLQLTAQHQAVQRHKVRNGSAQQQAGSAQQQAGSGAAAAAAAMAAVGPAAEEDEAAAERSAALAVMAAFDAEEAAASMVSRLLDTWNGVMVDYRVLMQQLYGGGGGSPQAGDLQLAQALRVGPATHYLMAAAVAAAVAAAEVNTAASLRRVCAADPSFVPSSSTTSGGSGGGGPAAAGTAAQAAGTATGAAAGKGVQAPPEAPAAASGSQQALLLAAAGRVQLHGLPPGLLPPPLVSLYEPGNYEANAGRSPAAASEVAVLNAECVLNVITWWHIGWAADGRLWRPPLGRRALTALALQAAEAGLQRWRSYQDLYPPLNPPASAPAEVQARGASGAGGGAGSSTGAAIGAPGAAKEAKRQPAKPLTQKQLRQQAAAAATSAKQQAAAAAKQAAAAAAEAKRERQRQEVAKAVATARRESRLRAWLPGGFAPEMRFRLVLGSFEFVCSTHSLEVCEDPAPLRRMAQGEQQRYLELLRRQEVAAESEAAAAAAAAAAGGAATSSASSTAASAVAVAAPQQVAEGAAAWAPPAPATATVTATATGSATLRARPAEVALPERCWHVVVGAIRALAGDAERHMWPAGTTAGHVQELLQQVLSGAEEDSRAALAARLLVVEAEAANPPAAASHSSKDTGGGDKGGGSSSSSSSSGSSSSQQPQRLLPSCTEAAAATATTAAAAASGIASAAGGNDTSSAPDALKPAAAHQQQPQAQAPVPPQQRPSHDGDDDEQWLSGAAAALVAAKRAGLYRGLSLGLLPSLEALLRGIARECAAVEDWGDAASLQAISLVNAVLAHLLDLDAVEHMVLEAAPRRQAAAFIVSAAKASCAATRAVINTFWGEVRRACQPGKGKAYVKSSAPARLGPCAELNVPLRLLGTLRAAGTLCGGSSGSGSGNQAAAAGMEEEQQEQQQQQQQRWRRRPGRAELVSLLAATWLPALAGNVRAALELKAGADPLTAERTAPMLAALVLPHLRWVPALAMTMAEAGRRGEWQTALEWHLLLVTDAPLLIAVISTAHGVLPPGSEEEGVVVTAAQALWAVHPTCMSTCPQQTALTGSLALVGPGPLAAPWAPAEEAAAGRTAVLAALRAGHGWEPPPESPESEDGSSGSGGAAAAPYWEAPPAEHLDLLLAPSMARSRLGLCERAGCRNLRGDSESGVARPHGARGMWVCSQACAAEQECFLAAVDKYCKM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B8V0</accession>
    <name>A0A836B8V0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">NIF system FeS cluster assembly NifU C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_004509</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the NifU family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000010">
        <property type="protein sequence ID" value="KAG2450669.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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        </source>
    </evidence>
    <sequence length="3665" mass="368794" checksum="70EA732D58E47689" modified="2021-09-29" version="1">MWRFRNPKVIKVPAWSAEPQINRRVPGGTSMAAPQAVPPAQSSDCSKAVPFSRHLQAIIQKDYAAGYLCLTMLGKSTTAMWVLLEVLQQAQAQQLQPTPSSRKALQGDASAGPVLARALEELSAPRPLVHKMAGAAGGRSRTSVPSRAGLAEMLGLLAPGGGGGPAATLPQEKAGPHTAVQASVGPLADDEARSAGDVAGAFPLPPPRATAASVSAGGDGIGDGGSAGGGGGSGGGSGSDGDQQPEPEPEPERGPAAPAPLHWLAVALSLSLVLPPAGVVELAVKLSRKVLAHPSTLVSASAAASGAPGSPSRRPRLARREGPRRRRFALVQHAAAQASDGENVLLLHPASVAAALLFPAEGSGAQQHRSTAADELRRVLAAAAALVPDDQRFRFQVSSPQWLTPLGSAAGDEGSSASGAAGVDGGSSSTSGGSSSTANRRAEELASMSLRCQLAGLADALEAAREREAALAARLIARRAVSLAVEQGKVAELTAALDESGEALAASQSRMDAIAAHMEELQSDLEADMAMVWGQMQDVAAHRDALMAEMEADAQAASVKSAQLAAVAAAREHLVAKLAAAEQAAREAAAQAAERLEAADTAVRAAGSERDQERARAADLSAQLEAAMQLAVSLEGALGGSAPPDASSARVQLIKPHQQHDSDDDVRSPTDDIARPLDLLATAAGPTSAAAPGGEQQALQQSLRRLQQRAGELAALRQERAELAAAVQAAAAAQAASAAALAASRAEGLALAADVSRLEVALAEAAAARQALEGELSKTCCMLSELQGRLRHSDEALAEARRGWNDSEAELAAVRSQLEAAMGGGVVLGVGSVVNGQSGSVQAAERLAAAACERLACLQAHCAELGEQLAAAQRERQDLQAALGDSRSERAALEQQLVASGGEVEAAQRRLEEAAAALAAAAAEGAGLREQLGATAQKLADAEAEAAAGGTRSRAAEEATAALVEQLEAARAQVAAAQADAGAARTALERSAEAAASAAQALRAEVASLQRQLAAAAAVREASESAVEALQLRLSTVEEQLEAAASARRALDGELAHSAEREAALRSELAAVRQELEVAQAAVAAAREAEDNRAAAVSAAATNAANLQDTVSELVASLEAMEQQLQQARSGGGAALAEAEASVCSLQAQLASRDAAIADLQQQLERVASELEAARAAATGAVDAKAALQEQLAAQLAELAAAMQAAEAAHAAAAAAAATQHAAAAAELEGRCSDSEAAVASLRLALADSEAARLGLAEQLTGAASQRSRLEARNEQVEADLQALRVAAAEAEERQARLQEQLAAAEAAGSELVADAAGRDAARSELQAALAASEAAHEAAAARLSEVAASLAELQRRLADSEAERAALRSELSAAQSAGTELEQRLAAADADRQELTQRLAAAATERVELAAALSAARNSAVELEAALAAADSDCGDLQQRLAAAVETRASLEASLAAAGGEAGDLGRQLTSAAESRRELEQQLAEAQAEARSVAEGLAAADAERAALTARLTAIATACQELEAQVAAAQGASAQLRAALAEATAEREGLQAQLEASAAALSDTVAQLATVKAAQTELEQRLSVAAADAETLRARLADAEREREGLAAAATQAQADNARLTQLLSQAEEQQRITAAALQVAEVQGAALAAKLIESEERQQTLAGKLEAAETEAQQLSDRLADADTKAAAAQAELQERSADLAQETAATAQARAAAAAAEAARAETEVALTDARAAVAQLQQQVETTTAEAEVLREQLAAAEADRSQLTAVQAAAAAAAQALTADLTAVTSRLAETEARLRASDAVITGLKAQREAGDSAQKDLAAQLAASQAEAAELQARTAAQAAQVVALEEELEQAAARAEAAEAEAAALRTALAEAEVREAHLQEQLDSTEEMRSALEEEAEASDAVCAQLQARAERLEVEKAELLEYVAELEASRGSLQEALEAAEASDAEHRAQLEAAVTSAAELEQQLAAALEADAAGRQVLQQQLDEVQSALDVHTARLAAADAASAALSAKLSAAEAEAAGLKQQLAAAAQCRGELQARLASAEEERARYYDGLATAEGQQAALAKQLRTSQAEAAKLASELQAGERERSQLAERLAASEAAAAELRAQLEAATSERSSLASELAGTEVARVEVSRQVQDISMRLARKSDTAVIRRMTQTTAVLEQLEELAAAAEAERRAMQAREAELLGRLEGLEAENGGLVVRGVVRLALARACLSAVDSERAALAAQLAELTSGFGGLLGSSAAGSPASFAAGGGCGSRLVVSPGALGLGLGAAEHSGVTSPTVAAAAGSSSGCSSGGGRTGGGGGVEADSRQERVRDLEAYKRQLDEVRRQMEETLREAGCSMAGVDAALSVPCAFPQLNLQGQQRPAGPGAVGAAADDEARRDSFSWMPDMTHMGSMLQERPRGATQGSGGGGGSGRDQQQQQQLMMAVGLQELQVHFNPSAPYSTPATTHRQYGRGGRAWTGGSGAVGGGGGGGPHGASGGSRLAPGGSAARGGGAGAGGYSPSDSGAPSPASRPTPPRPLEAKLAALQAQLNRAGELGRMWDERLDAAAGPPAASIMETVAARMQAQAEDILKSSAEASLRGSHESQQEEAQQLAAHPYHHHHPHPYHHHHHHLAGSNGDGEAGLLLLQGGAQGDGAQQHQQQQHLHMQLLRGSFIAESEQEQEREREDQGCREQEQGQDGAAYTRLEEGRSHGRRSHDSGPAGGVVSPTAAAHRASTSTSPPLDLGSVAQSLLALRGGVSTLLATLAGDKEAGAGGGGGSGGGGGGSSDSEVGEGGSVSLRCSAQSGPSSAAAAAEQQQQEALLLALMAHVQSLEQQLLGAHMPLPPAQPAFPATARAAATAAGAAGPATAATATVSGGGMLLLAPSSGRTPASYGRYHDHRTAAAMTVNTTAAGDDEDRHPHPHHHDDEDDEDGDFASPPHSSAGSPADSPRKPLAVTVGLSVDGGGSQGVKLTLLTSAQQAAAGQAQAPAQAEAAAAGAGAGAGAGRRLAAIHAVAFEVAPAEAATGTGACAPPASSLTWLVGAKVDGGAKQQPQQPQPGSGRKKPAGGRGEVATAKAAAAAAWTAGLQQQPQQQGLAQQGDQEQQGQQAAAVPVDAGYSSKDATSPIMPLGCVTRAVNNGAVATTATTTTPRSAATATGPVSAAASEGCPSSSLPDSSATPRAQGVSAGTPMARAASGIAAAAGGATPNGPAASTRPLDASAAEQMLRYSNPCFARTPIAAAAAAVAPASAAAGADSGAGAGDMGVEEGGGPAVPVMGDLDAVADDAADHHQQHHQQHQHHLDSGHHRDGGGAGGGGGGTMMMMPPPLPLPALEMTESVDITALRAARRRHVVSDGSGDAGAAASGVHDGRTSAPGNAPSWSVSASGFPQHPPARTGTAAAAPGALMHASHGSGGSYGGAPLPGSQRTSCAGSVAESLPGGAAASAVGGGSGGGADVSYKVDPRASGGGGGLFCMPLVSRSSRSRKFSFRLPSRQGSRSSTVYPEHVQSAAAAGGSSSAAGALPHHHQGDLLLASHDNLSVSSHGTIGVTQPAATFHHPHPHGPADLHPSAAGTGAQQQQHRPAGSMEHMSLSGGGAGALLTPSALPPPPLPPLPHKSSSSSKSGSFFKKLKRAVGMGGGSSSGGGAKAPVSEPPQPTPTPRMSAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B9U7</accession>
    <name>A0A836B9U7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_003153</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452121.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B9U7"/>
    <dbReference type="OrthoDB" id="555110at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="261"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="274"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452121.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="329" mass="34883" checksum="ECCA12BB93A124EF" modified="2021-09-29" version="1">MAELKRDRNDTTTASAAPRTASGDTAAPSASQALSPLGSPGFQRSAPRARRDALESRNPGRPVRHPNHLKVLADLRMVLQVLGQPASQLLLLRELLDPAAGVEAAKLPPAFKVLLGSFATTRDDGTLFLDYPMLAQVLQAVTTESGELLEAITAVQSISSKMFRELVVLAGHAAGDGLVYAAIYLQALDHRCNSRGGKANFEKTHRAQATEDAKVGLRWFHALLRNVLCHGYISEQRQALQAYPPQLAALHSSGRVGKVLTKTFDSPPPTRSKAPVASAAAAPRSAAAPRAQLQPPGAGPAVRPIVSLHLGKRLGRAAGAAVIPRRYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B9X0</accession>
    <name>A0A836B9X0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_003524</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. RAF subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451745.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B9X0"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd13999">
        <property type="entry name" value="STKc_MAP3K-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000060">
        <property type="entry name" value="Serine/threonine-protein kinase isoform 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045865">
        <property type="entry name" value="ACT-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002912">
        <property type="entry name" value="ACT_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF261">
        <property type="entry name" value="ZINC FINGER CONTAINING PROTEIN KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55021">
        <property type="entry name" value="ACT-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51671">
        <property type="entry name" value="ACT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="ACT" evidence="12">
        <location>
            <begin position="153"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="11">
        <location>
            <begin position="277"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="221"/>
            <end position="249"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="10">
        <location>
            <begin position="227"/>
            <end position="243"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010507"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2451745.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="557" mass="61289" checksum="A3FCEB44A5955817" modified="2021-09-29" version="1">MASGRKRTKADVCEAFLARLSERGDVELDSSLLEGIRQHFDRLPTRYALDVNVDGLDVLSHKRLLDEARADPTTVSFAVRPVEIVGPRSDGVSSPHELTRANSKKLGQLCRPAFGSSPNLQALALEVGERAEGHEAEASSGPGPREEHPVFYEITIASVDQPKLLSRLSEALGDLGLNIREAHAFNTNDSFSLDVFVVDQWQPQPGQNLEELLGQRLLQMPPPPPKGGATPQQQPIAAGPAPALRIPADPPPNLSMLAGPRPDSPAVDDWEIDITQLHIEAKIASGAFSNLYKGTYCGQEVAVKILKDVHDDSSQYQEFLQEVAIMRKVRHKNVVQFIGACTRKPNLCIVFEYMSGGSVYDYIRREGPLKLSAILKLAADVARGMDYLHQRKIIHRDLKAANLLMDDNAIVKIADFGVARVIETTGHMTAETGTYRWMAPEVIEHKPYDEKADVFSFGIVLWELLTCKVPYADMTPLQAAVGVVQKGLRPGVPANCPPLLGELMEACWTGNPASRPSFRELTPRLQQLYSMALDEEKRQLEAKPASKQGLLSKLRGK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BAE3</accession>
    <name>A0A836BAE3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_003126</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452090.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BAE3"/>
    <dbReference type="OrthoDB" id="66620at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140359">
        <property type="term" value="F:ABC-type transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd03213">
        <property type="entry name" value="ABCG_EPDR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003593">
        <property type="entry name" value="AAA+_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013525">
        <property type="entry name" value="ABC2_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017871">
        <property type="entry name" value="ABC_transporter-like_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043926">
        <property type="entry name" value="ABCG_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050352">
        <property type="entry name" value="ABCG_transporters"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041">
        <property type="entry name" value="ABC TRANSPORTER G FAMILY MEMBER 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48041:SF139">
        <property type="entry name" value="PROTEIN SCARLET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01061">
        <property type="entry name" value="ABC2_membrane"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19055">
        <property type="entry name" value="ABC2_membrane_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00382">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00211">
        <property type="entry name" value="ABC_TRANSPORTER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50893">
        <property type="entry name" value="ABC_TRANSPORTER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="437"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="466"/>
            <end position="490"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="510"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="543"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="576"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="domain" description="ABC transporter" evidence="9">
        <location>
            <begin position="18"/>
            <end position="268"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50893"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2452090.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="683" mass="73164" checksum="AAB4E3C2C8E7C705" modified="2021-09-29" version="1">MTAKSTGSSARRKQGALIEWHDVSYTVTDQVTKQKKTIISNMYGLAQPGRLLAIMGPSGAGKSTLLDVLACNNSSQGAALSGRITVDGAPRAARQFAFISCYVQQKDVLLSSATVREVIHTAALLKLPYRGMAAAAKRELVEATLKELDLAGCADTLIGDETIGLKGISGGQKRRVSVGIELVKDPRVLFLDEPSSGLDSEMALGVMSSLVRLARKGRTVVCTIHQPNSDITDCFDDYLLLAGGRTLYGGLWSGAVDFFARAGYSCPSFKNPTDYFMSVITRDEAAVDTLATAYAKLRLGLLAEAADEGRATASQLGLSATAADGGWSTYSTAGGGALSATPQSSSRLAEFAATAEAADDGEEMKGGGTAAAVALDVESGSGRGSGGGYADRADVDASGALEEPAGPLVPVWFQVGVLTARVWRTWIRSPVMLASELVQYLFFALFVGLMYFRFNDKLGEGDFNRIACIWFSFAVLCFTPSYTAVTSWAAERLLLKRELDQRLYGINTYYLARYAVLLPFEMAQCALFLCVMYFFVGFYPSAANFFIFFAVLSMFQIISEGLGVCCAVVTKTPTSAVIMLTFVLLVLLSFSGFLTVKTPVYFVWVQKMSFFTYSFSALLDTEFAKISFVGAEGQTVPGMEVLPASVDTGLTTAQNIGVVAAQVGGMELIKLAALHLAYRLKWL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BAE5</accession>
    <name>A0A836BAE5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_003058</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452019.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BAE5"/>
    <dbReference type="OrthoDB" id="336747at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24347">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="11"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="41"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2452019.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="312" mass="33550" checksum="6E8BA9E97AA0B9A4" modified="2021-09-29" version="1">MGFRADFNSQYSLLEVLGKGNFGVVWLAASRHDPSHQVAVKILPKVREDKSREETLACIKREVALWGSLSGDSRYVAQLLGLYEDGGSVYLVQQRCYGDLATAMQSGPLSEPCAAAIMWCVLSAIRDCHDHHLAMVDVKPQNFLLTSPPLALPAAEARAEAAASVEAGAPPSAKAGAKEGAGARREAAQCACPVPLLLAPEHQAAHTAAHGPCVVACDFGCSLSYSELMRGGRHGGSPIFFAPEQFSSSYGLGVDVWAAGVMLYLLLSGRYPFWDCKREDIKPGMKPYEVGGGVGGCWWGPRTWMWYVNVPH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BAE9</accession>
    <name>A0A836BAE9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_002636</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452393.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BAE9"/>
    <dbReference type="OrthoDB" id="509153at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2452393.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="103" mass="11411" checksum="2A0D0A17B8F21FC5" modified="2021-09-29" version="1">MLQAFARQTLQARRQGLHFRTAWSLTEALGLNKGKEPVDVYAIDPKLVLNPEKLKAADLDKVAARITVCRQLLPKLSHGEPELAEMDEPGGKRLVLRRAGGDL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BAF7</accession>
    <name>A0A836BAF7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_002865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BAF7"/>
    <dbReference type="OrthoDB" id="541552at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00173">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="182"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="485"/>
            <end position="508"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="485"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="495"/>
            <end position="505"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="899" mass="95805" checksum="C5ED6B814845207C" modified="2021-09-29" version="1">MGGSTPPWFSSDYPDLAAKREPFPGVDRYQTSYVRYGQAEEALQGAWETETCRRTMAENGQDLNAFYPPGSLPETISLRIIEAPAEFALPVKQDRRLFPCFKVRVEAKHRGPFSLPLTLRAHVLTQQDKEHIGTWVPPEEDPNIDDKSQQRCGTELKGLSVIRHTWEPNARPEMKKFQHQLAMPPPAPSGGATVKAEPSNSSFNGAMGPGNGRNMAHLFGGDRPDPVVTLASSAPLGGAGTGRDSLEAVMESLINAGPLSNPGNGGGVDSVASESNSGKLVNHMRTLQAQQQAALAAEQQAAAQAAALQATLQAQRAAAQAEAGGVDRRASVAQGNGAAAASAESRGFISFQDYEFTNLEFLKPTRMNKVFMVFTINIAGLDDLIYVAFNVPTIGICRAEQREKACKKLNIDFKLLSHFDHTGSNHANNNNNHNSNMNSDVSKSLALRANGPLGSALGGLPGVAPQSAMPSSVAAGGGGLSVSRLNGGSHSAGSAGDGSGCGSGSASGEVKATGGMGLHEVGMAQYATSQLQAGPGQQQMMQQMNALKQQQQQQAYGAAQQDVAFQLQQQQAQAQLQQQRMALAAAQQQQQQGLGNGMVPGAPGSGGGAGNGLGPTAEFYLAANGGSLPPPQGSAVGMGIDNGMGAMASRKRDQGPKEEENCRFQPVQQSDLPPYTAFAGLTSSDVDMLLPAPHSRMAMRDFINDVYESTGLHRKLTHMDMQALLSQAGFPSESMREHDTISQQQWDEFCAQFRNIVGTLQQVASVWNMEDPVVISGFDMDRAGTINALVNEPAGTFICRFSMSQPGCLVLTCKVGPTHPRADAMGLVHAIIKIDDLHERRVDTWIRDYAGATHLLDVYRCKRVDKRKVFATNYTRLRGLEVGDVPPPAPFAMTPGGFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BBI6</accession>
    <name>A0A836BBI6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ShKT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_001824</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453607.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BBI6"/>
    <dbReference type="OrthoDB" id="2015991at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056508">
        <property type="entry name" value="HPAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485:SF7">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23452">
        <property type="entry name" value="HPAT"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00254">
        <property type="entry name" value="ShKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="873"/>
            <end position="894"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="9">
        <location>
            <begin position="586"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="645"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="782"/>
            <end position="809"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="695"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="782"/>
            <end position="796"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2453607.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="907" mass="103113" checksum="246714E24FF952E1" modified="2021-09-29" version="1">MVFSYKRSRQPHESQITRIMCCTDEERKRYNEQLLSIVQTHVAPSFAKNEKTGDFYAAYNKPGAVYDWLKHVDPPEDWLLVLDSDMYLRRPFYPQFFNATRGWCQSADYTYMVGVNNELATRHIPEIEPRHDTLAGPYGRRGDQVGGFFFMHREDMKRVAPLWLKYTEDVREDPESWRLTGDQYVEKGGKPWISEMYGYAFGAAKANVWHKWDKKTMMYPTYRPTDCQMYSDWQSVGAAFSFKMSGQPGSVIRVMCCPEEQAKKYNKGLLGMVDTWVAPDASHSKRTGDRYAAYNKPEAVIDWLDHNVPKHDYVLVLDSDMVLRRPFFVETMGPRKGLAVGARYTYMIGVANELAVRHIPHVPPRNDTLAGPFGRRADQVGGFFFIHKEDLKAMSHDWLKFSEDVRVDDQAYRLSGDVYAIHPGDRPWISEMYGYAFGAANHDVWHKWDTFSMIYPGYEPREGIPKLMHYGLLFEIGKNYSFDKHWHYDFDVTVCPPWDLKDPKRRTHGIFPEPPRPSSLKKDDFIGYYKDLLAIETLATLNAAFCDYHISHCPPSEQLVSVCKEVFSLYNEAREFIQEAEASYDCQDFHPKCAEWKESGECSKNENYMTENCRKTCDKCNKVEKYFPETTTKELEEKLAKMSKELQPLSEDPDSKGGSGTAPTAQSPQVIPKQEQPVTIIPRNVAPPKQEVRTSPPPMQSSPPPSPPPVESPPPDSPPPKRITRTTVMDSRKTAQKALMVRCYKLSLGIDEVKDCVKAAKEGKEYEVPKKVAAKAADKEVEAAPKAKHTESHLTLDGEGATTETGNDAVDKAKAPDATAEGNAGKKNVRVVQRDLEDLSLTQGEGKKGKAPVIDAPVVGPSLHSLLGRLNTWQALVLWLVVVVAFLALVPRIAKLRRRQRSGMRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BBJ9</accession>
    <name>A0A836BBJ9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">ShKT domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_001824</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BBJ9"/>
    <dbReference type="OrthoDB" id="2015991at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.1940">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056508">
        <property type="entry name" value="HPAT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003582">
        <property type="entry name" value="ShKT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485:SF7">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23452">
        <property type="entry name" value="HPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01549">
        <property type="entry name" value="ShK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00254">
        <property type="entry name" value="ShKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51670">
        <property type="entry name" value="SHKT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="637"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="domain" description="ShKT" evidence="9">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="409"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="546"/>
            <end position="573"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="7">
        <location>
            <begin position="459"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="546"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2453606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="671" mass="76217" checksum="307BDC7297658641" modified="2021-09-29" version="1">MVFSYKRSRQPHESQITRIMCCTDEERKRYNEQLLSIVQTHVAPSFAKNEKTGDFYAAYNKPGAVYDWLKHVDPPEDWLLVLDSDMYLRRPFYPQFFNATRGWCQSADYTYMVGVNNELATRHIPEIEPRHDTLAGPYGRRGDQVGGFFFMHREDMKRVAPLWLKYTEDVREDPESWRLTGDQYVEKGGKPWISEMYGYAFGAAKANVWHKWDKKTMMYPTYRPTEGIPKLMHYGLLFEIGKNYSFDKHWHYDFDVTVCPPWDLKDPKRRTHGIFPEPPRPSSLKKDDFIGYYKDLLAIETLATLNAAFCDYHISHCPPSEQLVSVCKEVFSLYNEAREFIQEAEASYDCQDFHPKCAEWKESGECSKNENYMTENCRKTCDKCNKVEKYFPETTTKELEEKLAKMSKELQPLSEDPDSKGGSGTAPTAQSPQVIPKQEQPVTIIPRNVAPPKQEVRTSPPPMQSSPPPSPPPVESPPPDSPPPKRITRTTVMDSRKTAQKALMVRCYKLSLGIDEVKDCVKAAKEGKEYEVPKKVAAKAADKEVEAAPKAKHTESHLTLDGEGATTETGNDAVDKAKAPDATAEGNAGKKNVRVVQRDLEDLSLTQGEGKKGKAPVIDAPVVGPSLHSLLGRLNTWQALVLWLVVVVAFLALVPRIAKLRRRQRSGMRTE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCL2</accession>
    <name>A0A836BCL2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">ATPase AAA-type core domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_000381</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the AAA ATPase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BCL2"/>
    <dbReference type="OrthoDB" id="541358at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003959">
        <property type="entry name" value="ATPase_AAA_core"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003960">
        <property type="entry name" value="ATPase_AAA_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050747">
        <property type="entry name" value="Mitochondrial_chaperone_BCS1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23070">
        <property type="entry name" value="BCS1 AAA-TYPE ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00004">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00674">
        <property type="entry name" value="AAA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ATPase AAA-type core" evidence="3">
        <location>
            <begin position="221"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="50"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="70"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="82"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="113"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU003651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF00004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2454536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="386" mass="38630" checksum="5EA9D78528D79DF6" modified="2021-09-29" version="1">MDIMTDTRVLLQRRQTSGGGGSSKRSGSNGDEDDEGGSSCSDEDDEGGSAITLPFNKVIYVLEDVDAAGGVVARRSPPPQPQQRQPPAERTAPDTAPAAAVDSSGVLNGGGSSSSSSSARSSMGGDDVAPSDLSHRRRGPPAAADAATAKTWAAAEPACVRASHAAAEAGAEAVALAAALAESIVGSCNPGSSSGGHGQGHAGCGHYSAYAGYASSFRRKHRDDALNLAGILNVLDGAVDTPGRIVVMTTNCPDSLDPALIRPGRINKVLYLGRLRLAEASAMMRHYCFPGPAGAPGGAGAGGVGVDGAGGGEAVEAARAWEAEVAEAEAALAAVWVDDVLSPAQLEAMCGEAETWQELVEAVGAAIGSGGTGGAEAAGWNHFERC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BDK6</accession>
    <name>A0A836BDK6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_000686</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BDK6"/>
    <dbReference type="OrthoDB" id="10619121at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="168"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="333"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="73"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="345"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="416"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="456"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="488"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="513"/>
            <end position="523"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2454854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="585" mass="61005" checksum="A61986C5F7E44AAA" modified="2021-09-29" version="1">MEENLKLRRQLAEMQRQLTLTQTAQRRGEAEAARLRTSLARAEEMMGQREAGTLSPNSMASQLYRTPETTSLVAALRQRLEDCEAGREDLRRELERMAKSTRATAVAELQAEVQACSEETGRQLARAELLAGRTAAATAEVVELRRQLAEQAAAHAAAQVRLEEETQCLHDQPGRTGAAAGHGRHHHSSSSSGPSTLCSPPRVNRRDGPETEAVSSKVASGGGGGDSNRLAAANAAATLAELETCAEVLLSHAHLINARVPLGPAHRGSMAMLEAWVRNRGPQVAGAPAVLRTLRAHQGRLHAALVALPGGPIFTNASLAALTVLAAQAAAQPVADAPEPGQGDDGEHSNSERGQQRQQQLGKAGVEPQTPQPRAHPISRVASTRGGGTGPTQPHGQVSPTKGAAVAGHSPSLACAPPPAPPFPPQQRQPPLAVPRLKLPNAGGSSGLPWIPPSVVEEEPEEVESLDSVPTAATPAQTHAEVGSSPRAAHGVGSVGAASPIGGGAGRLPSGRVDNRSKYDVIRSRQQQHLMEPVPLSQEPGVTGGSGGEAHTAIVAARGVEAISTDDSWQELGVEEVDEDLDGDY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BDN9</accession>
    <name>A0A836BDN9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SRCR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_000786</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454959.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BDN9"/>
    <dbReference type="OrthoDB" id="535813at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.250.10">
        <property type="entry name" value="SRCR-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001190">
        <property type="entry name" value="SRCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036772">
        <property type="entry name" value="SRCR-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56487">
        <property type="entry name" value="SRCR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50287">
        <property type="entry name" value="SRCR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRCR" evidence="4">
        <location>
            <begin position="1"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="361"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="439"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="380"/>
            <end position="415"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="452"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2454959.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="723" mass="76282" checksum="B8CA4CC9DFD5DC6A" modified="2021-09-29" version="1">MPVCLPSWGADAAWLACRAAGFGAGGVVAYTSANSSANGAYPNVEFPGNPRFNWRIITDVSCPPGARRLSQCSAVLREWASGLCKSMAAVVCVLPARLLPSTLHFDTQLTSAQTSSCPEQLEGEPPCLAIWRAMLPYSLPLPYGWRAQLMYFQPQCYFTDAGSGAVAFDVAADAAGRCTGELQTDLHFWGGAAGASGGFTVITVAYLHGDDGGGAPGTDPLLTLTASYLGPTFQLSGTEVYMVETESGQVGFVADLPPRYQQWMMQAFVREPGGANSAVYRSPDQAAGAPGFGLELTAGFEEEQPLLAPDFDRLLLGQDSFQSEQQLHGDLALALVYNRALSPPELDELYRYYAPRFGWELAPAPPPPPRPPRPPRKPRGPPLPPPPPPPPPPPPPPPAYGQYPPPPCHRAPPPSPYGGYGGYAGGYGGYGTYSDPGSYGGYGGSPDDPCSAPEPPAYPPPPSYPPLPSSPPPPPPPPPPPPPPPPPNLPSPPMAPRPPPRPAHLPRPAPDTCHGLDPAACAALPWTLAFSHVGQTQYPYTDDWWGQVTPVCFALKYRRPAATSDGSGSSTWPPPSAAPTCAAAAAQSGALPRAVQLLAPCPRCVEGSTYDIQYDNSMAMIYAVTVDGAEVPIEVKEVRAYGSADSQIGLSIPLPVEALTAAAAADDSSWQQRGRRRVAAGVEVCVQVLVSHDMAGPDPLRTFVGMFLGQVRITHARVRLKAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SIB1</accession>
    <name>A0A835SIB1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015380</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000181">
        <property type="protein sequence ID" value="KAG2422944.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SIB1"/>
    <dbReference type="OrthoDB" id="338531at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042293">
        <property type="entry name" value="ARID4"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46694">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46694:SF1">
        <property type="entry name" value="AT-RICH INTERACTIVE DOMAIN-CONTAINING PROTEIN 4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="451"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="546"/>
            <end position="607"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="576"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2422944.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="625" mass="61784" checksum="F311CE457A27CFE1" modified="2021-09-29" version="1">MALNGARWRVLACVPASDDGLGGVQGAILDLAGPENGPSNVQVVTLINPSLPEFNDAVSTNRPNFIYVAGPLLQREEKSAGVVGAFHFRGDTTPGEDTLLSALAEARPEVAYVDAVVSPHFGPSLHQRGVTSVVVWPAGTAIPTAVAAHHNCAFAAFLVNTHASPPEAFSAATHSTQAHCLVLGSDGTHTAPPLPAFVGAARPALPDSTSIPPLAVPPGLQQQLDPNNLPAFPGWTDVRLLAPRAELRLLLTGGSGLVDSTRLSFLGEALRALLVMEARGLQLTARTPLEKLPRNLPAGCAAARCEYSTSSGAPGSVVLGAPPGVLEHPALVEHALRMTLVTDAVSLQFRLPPPGLSLPTPRSSKAVAGGTPVVDTVVVTSVWAVEVLRSLCKEPRYRSLAALGVAAVGNAADSAFTPSDVARMGLIAGGGLPAAAANGAAAGGTIAAASSDPASAQAPGAGGLQTADTLPSPSAQAHGAGGMGAGAAGAGVDDVIMTDMPAGLVDGAHTYFGADAMMGYAMNGHLHFLGNSDMAAAAGYAAAASPDSPVGDGLGGSGDGAPAGPGAGAADGGGVAGVANGNGTSPHDGWGSGGRHDKPPNFTGDLPVGVGGVLGGDVLGSGLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SIE4</accession>
    <name>A0A835SIE4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GST C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014534</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000099">
        <property type="protein sequence ID" value="KAG2427703.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SIE4"/>
    <dbReference type="OrthoDB" id="414243at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004364">
        <property type="term" value="F:glutathione transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1050.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.30.10">
        <property type="entry name" value="Glutaredoxin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010987">
        <property type="entry name" value="Glutathione-S-Trfase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036282">
        <property type="entry name" value="Glutathione-S-Trfase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040079">
        <property type="entry name" value="Glutathione_S-Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004046">
        <property type="entry name" value="GST_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050213">
        <property type="entry name" value="GST_superfamily"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036249">
        <property type="entry name" value="Thioredoxin-like_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11571:SF263">
        <property type="entry name" value="GLUTATHIONE S-TRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14497">
        <property type="entry name" value="GST_C_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00019">
        <property type="entry name" value="Glutathione_Transferase_(cytos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47616">
        <property type="entry name" value="GST C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52833">
        <property type="entry name" value="Thioredoxin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50405">
        <property type="entry name" value="GST_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GST C-terminal" evidence="1">
        <location>
            <begin position="147"/>
            <end position="281"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50405"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2427703.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="287" mass="30868" checksum="C5F9A3C399047008" modified="2021-09-29" version="1">MCATLRSVKQATLIGAPRTRLPAPVLRHLQQRRSAASRCRTAPARSVSPAAAAAAAAAAAAVAVGDMSGIKGRGEYVRLVFEEAGVPYKDMGQGAGFAGIMEFVWKGGNTGFPIRAPPAIRRGDFTLSGTPVVMAYLGRQYGLMPADPAAAAHVEQLLAVVTDGVGEGRLAFHPKDHYASHKTQVEESVPYIRQYGEQRLPKYLAYWEAVLAANPTQSGFLVGPELTVADLAVYQYMAAAQQHYRQWYDAVEAPAAKAHQARIAARPRIAAYLGSERCLPWDSDSMM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SNN8</accession>
    <name>A0A835SNN8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Glycosyl transferase family 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013763</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000079">
        <property type="protein sequence ID" value="KAG2430403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SNN8"/>
    <dbReference type="OrthoDB" id="734129at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000506">
        <property type="term" value="C:glycosylphosphatidylinositol-N-acetylglucosaminyltransferase (GPI-GnT) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017176">
        <property type="term" value="F:phosphatidylinositol N-acetylglucosaminyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006506">
        <property type="term" value="P:GPI anchor biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2000">
        <property type="entry name" value="Glycogen Phosphorylase B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871">
        <property type="entry name" value="N-ACETYLGLUCOSAMINYL-PHOSPHATIDYLINOSITOL BIOSYNTHETIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45871:SF1">
        <property type="entry name" value="PHOSPHATIDYLINOSITOL N-ACETYLGLUCOSAMINYLTRANSFERASE SUBUNIT A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53756">
        <property type="entry name" value="UDP-Glycosyltransferase/glycogen phosphorylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="184"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2430403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="184" mass="19725" checksum="CBC6065A1709F9AF" modified="2021-09-29" version="1">MALVEAAAAGLVVVSTAVGGVPEVLPPDMIVLTEPSAEGLLEGIECAIQRVPHQRPLEQHLRVRHMYDWNDVARRTSAVYDSVAASCRDDSLPARLARYLAAGRWVGALFSVVAVLSVLQLRLAEWWRPASAFDVAPDWCELHLHAAAASADVDTPGAGARGTRRAAGTMPTNVHGQNGAMMRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SR30</accession>
    <name>A0A835SR30_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015094</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000119">
        <property type="protein sequence ID" value="KAG2425045.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SR30"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="73"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="187"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="227"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="257"/>
            <end position="270"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2425045.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="308" mass="31450" checksum="D0B22384761BFFF2" modified="2021-09-29" version="1">MLSKHGRTLALSAEEEDMLEEARKCDSDAQEVLQPDLRFTYYTKARDIFSLERLAANVERKLAAAAAAAAASPAGTPTKAKAGGGTPRKGTQLGATTTEAAFDPSHLPLPAALVYAIQAIMERSQVAVLESNLEAYGARGHELRDMAGTLRATATRARLVSGGAGPQEGARPRAPARPTSEQHSNDSAEEEEEEEEEEEEEGSEEYEEDGEQDDGEAGEQEDEAADEAQQAGQVPATAATATASVASGSGSETGNPAASGPSTTATATGPATTAEAECYVAAAMGGLKVAGGAEAAATAAPTKTAANA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SRW5</accession>
    <name>A0A835SRW5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Nucleosome assembly protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_014372</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 3">Belongs to the nucleosome assembly protein (NAP) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000092">
        <property type="protein sequence ID" value="KAG2428568.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SRW5"/>
    <dbReference type="OrthoDB" id="547411at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000724">
        <property type="term" value="P:double-strand break repair via homologous recombination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006334">
        <property type="term" value="P:nucleosome assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1120.90">
        <property type="entry name" value="Nucleosome assembly protein"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037231">
        <property type="entry name" value="NAP-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002164">
        <property type="entry name" value="NAP_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11875">
        <property type="entry name" value="TESTIS-SPECIFIC Y-ENCODED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00956">
        <property type="entry name" value="NAP"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF143113">
        <property type="entry name" value="NAP-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-0472">Membrane</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="820"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="52"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="223"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="430"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="647"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="739"/>
            <end position="781"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="66"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="223"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="276"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="332"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="443"/>
            <end position="453"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="454"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="661"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="739"/>
            <end position="773"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00009947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="RuleBase" id="RU003876"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2428568.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="8">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="856" mass="90090" checksum="DEC3D7BBCE5190B0" modified="2021-09-29" version="1">MAEKKVFAAIEAIEVQMEATHKKRQERQEELLVEHLRARQPLLERRYELVTGISEPTDEELKEFQPRGAAAAAPPTSSPSGKAGGGGAAAKGAAAGAGSGGGGGGRAGVPFFWLNALCNEPDLAPHITPRDRHALEYCTDVRYERGPAGMCVELHFASPNPYFENKVLRKGIYVKRAPPKAGSSGPGEIVEAREEATIIDWKPGKCLLVAAAPSAAAAAAGKKGAASGKKGGKQQQESGGGKKGKKGKKGQAQQQQQPAARSKRHGKHSGPAPDLPDPDDEEEDEEEEDDEELVGEEEGPSGGKTRPCPSFFRFFLPLEGGKTGAKRKELDPTMDPDDDEDEDEEEEDGLELDLEEEDEDEEGGGEGGDPRARRVAARKARDQDILDTLVKKVVPRAALLYLSGGGAAATAAALGAGGASAAAATAAAGRKKGSGGKAAAAKQRSEIAGHNAHEEEEEEDAEEEGGFTLVSGSPAGAADIAALPLTTQKALHALVVNQLRLDKLGAELKAGEWGALVAQAEEAARLGAQRRALLVGPASATSRLSIPAFWLRALRALDAGGAMVGRRDEAALGRYLADVRLVWQDLKGAGPSPEEPVRTATLELEFLPGNPYFTNPVLRKHFTFAAPGGSLTKLGVDSAQSDPIDWQPGRDLTVRVDKPKPGGGGGGGGRAAGRTRQVPSFFHFFSNAPGALCRAFNIPGQGRAAQAEAIQAQEEFMAEVINLVTYFAGRLAVETYVDADDLGDEKEDEEEDEEEGEEEDEEEEEDEEEEEAEPGAAAARRAARRAAARASRRGGGGGGGEEGDGPGFASVLWRLIKSGGAGGVLLGLFVLVMVVAQVLTFMDTLEFVRARFSWAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SWB3</accession>
    <name>A0A835SWB3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_006676</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000066">
        <property type="protein sequence ID" value="KAG2432692.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SWB3"/>
    <dbReference type="OrthoDB" id="510209at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="215"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="330"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="334"/>
            <end position="347"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2432692.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="415" mass="43398" checksum="32890205260B0EED" modified="2021-09-29" version="1">MHALPGTNGRVAVGNVVVPGETVEMKLARAKGYPYPRPDTSFLFINGNGSGGAPANGEQGQQGGGGGDVFLFDNEQWRGQQDLPHIRGRCGALASDFASARGVDLSQLAGQRMWPVLAIGSNAGPEQLRRKYPVEAFPGAVIPVVQIQLHGFDVAYTPYLASYGSCTATLEASLGTCVTIFITYLTEPLMERMHATEGGYNLTRLTGLNVAVAPHTAADSSNGNGHHDHHHHQQQQHPQNSDARSSGPAAGKAGTGSAPAAGAFEHIHTVYQYNHKLGCLDLPLTIRSAGQDGGGTECSPVAIAEIPAVGRAFPAATQPQMLAALRESLGMRGGSSSNSSSSSSSIGNGNGGGVAAPLQPVNLEAAGLVEAQEGLDEWILRMVRDDRLRQAVCARLAAHAARPFTYPQSEVMVTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SYA4</accession>
    <name>A0A835SYA4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011915</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000053">
        <property type="protein sequence ID" value="KAG2435414.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SYA4"/>
    <dbReference type="OrthoDB" id="496335at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.250.10:FF:000114">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043186">
        <property type="entry name" value="Str14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44920:SF2">
        <property type="entry name" value="RHODANESE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44920">
        <property type="entry name" value="RHODANESE-LIKE DOMAIN-CONTAINING PROTEIN 14, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="691"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="143"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="273"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="815"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="155"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="165"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="313"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="833"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="843"/>
            <end position="882"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2435414.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="912" mass="88744" checksum="EF7F47DFE26BEC4C" modified="2021-09-29" version="1">MSALNLPRASARLQAPRAVTQRASTVVPKALHNDASSSSILAGLASAVLLSSATPAFAEELPAVAVAPEVVIELSAVTGSESAVQSIAAPAIQEVVSEIASAVVTTDAPAAASAAASTSTAAAASDAATDLRSLLMQTLAAVEGRSAPKQQQQPQPQPAAPPAPAAAQQQAPEQKQEQQQPQQKPQQQQPQPEELQPKDASDSISASSAAAAAAAADAAEASRGAAAEVAEAAVGVPEAETVAAAAAVEQREASVVSAAEAAAVSAAAAAESSAQVVAESGPTSTTTGVAAASKEVEAEAEAAAEAATKEQRAPAFTAAANTSAASGEPSSSEQQPLAAAAPAADADASATAAAAAAAPDLPAPVAEPVVAVVEQAVSVESPAEVVVEEEVAAAAAVAAPVQVEEVVAAAAAEEASAAAAAVEASAAAAAPAAVEAEVVAEEVAAPEPEPVVAAAAAVEEAVEEAVAAPAAAVPEPEPVVAAAASPSAVVQAMQAVEEAVEAAAAPPASATITELVEDSPFAAPEALVPAEPPMPEAAAEAAAASAAAAVVEAVVEPVTEAAEATGAAAAAAAAAAATAATTAAASAAASAAAAAPSVDFKELLSGITAALSGATAASSGDAAAAPAPEDVERVTYLALGSAAVTFGLTFFVAPRFRSSFKEPVDWREMYRVLVARGGVKTVTPQEAAKRAKSGAVLLDVRLADKAAQRAAVPSVNLPLYRPIQGFDLAANIRRVGFAFFGIFGTELNPNFVAEVAAKIPKNKEVIVMCESGGTLDNKPGTQFGFQSRSLKAVYYLTMAGYTKVAHMKGGLGEWEREGLPTTVPSPEPAAKAATSSSRPGSTKGSKPASQSGSKAGSAAGSKAGSAAGSKAGSAAGSRAGSSKVGGGSGTTGKAPSPKDLVSAVNRTFGGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SZC7</accession>
    <name>A0A835SZC7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Choice-of-anchor I domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_011682</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000051">
        <property type="protein sequence ID" value="KAG2435968.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SZC7"/>
    <dbReference type="OrthoDB" id="425936at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055188">
        <property type="entry name" value="Choice_anch_I"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052956">
        <property type="entry name" value="Mesenchyme-surface_protein"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011044">
        <property type="entry name" value="Quino_amine_DH_bsu"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46928">
        <property type="entry name" value="MESENCHYME-SPECIFIC CELL SURFACE GLYCOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46928:SF1">
        <property type="entry name" value="MESENCHYME-SPECIFIC CELL SURFACE GLYCOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22494">
        <property type="entry name" value="choice_anch_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50969">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032784113" description="Choice-of-anchor I domain-containing protein" evidence="2">
        <location>
            <begin position="26"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="domain" description="Choice-of-anchor I" evidence="3">
        <location>
            <begin position="252"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="509"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF22494"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2435968.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="509" mass="53696" checksum="CE3EA573AE77028C" modified="2021-09-29" version="1">MSKALALALALVAAALSAAPQLGAGQTTEFPGCLPSIGLSLQRLSSFKSGPWTGTSSMEVLDYDPFSKLSAVVEARAQNVLALLVLNHADPANPSIHLRINVSTSAGEGGTVGVPNSVSVYNGYAALSLDGVPATAPGILRIYNLASGLKVGEAVLPGCAMPDSVAWTRDGGRIVVACEGEPATQVRAVVNDNAMCAAPIPWRTPANPVGAIAIVTATRTGSFTPAGSYPTYFYSLSSKLLSFQTYIDSLTDAAYAALLDKGMRVDPRLTKATAGRDIEPEYVAIPADKKNYNAYVTLQENNAVAVVDITPGRERIKAIWPLGWKNWTSASIDPSDKDGTRLRPVPGLYSWQQPDTIVHEAIGARSYLFIANEGDSKAEALAAKDLTAAALDPEAFPNAAALLADTELGRLSIDPLSGLKNGYDKTKAFDKQGPYNKLFAYGGRSWAVLDAETGEMVYESGDALEQLIAADPVASRCFNCDRNANIPDTRSDNAGPEPEAVEVFKLGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SZG3</accession>
    <name>A0A835SZG3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012217</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000056">
        <property type="protein sequence ID" value="KAG2434551.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SZG3"/>
    <dbReference type="OrthoDB" id="525813at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="38"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="64"/>
            <end position="85"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2434551.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="176" mass="19063" checksum="9F3992B214D9B947" modified="2021-09-29" version="1">MGRRDPYEGDAPSGPGGAFKMMSLLGHSRHQSSGTVGFFIKTLSVSACSSVVFGISSYMCLGWALGPVLPFLGGSAFGFVGGLVHRYRVDLDEARLMTARYPRVIEHHVRQVEPTELQCTSFESWLSGVPGSLKRQGVLVAALYSASDTISKLQDEEEERILEESYRGAAAAAEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T0Q7</accession>
    <name>A0A835T0Q7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Elongation factor Tu, chloroplastic</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_012139</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000055">
        <property type="protein sequence ID" value="KAG2434942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T0Q7"/>
    <dbReference type="OrthoDB" id="364892at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009409">
        <property type="term" value="P:response to cold"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042254">
        <property type="term" value="P:ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd16263">
        <property type="entry name" value="BipA_III"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03710">
        <property type="entry name" value="BipA_TypA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd03691">
        <property type="entry name" value="BipA_TypA_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd01891">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.30.10:FF:000016">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.50.250:FF:000001">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.240:FF:000002">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.870:FF:000003">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000055">
        <property type="entry name" value="GTP-binding protein TypA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.240">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.250">
        <property type="entry name" value="bipa protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.870">
        <property type="entry name" value="Elongation Factor G (Translational Gtpase), domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00849">
        <property type="entry name" value="BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006298">
        <property type="entry name" value="BipA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048876">
        <property type="entry name" value="BipA_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047041">
        <property type="entry name" value="BipA_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047042">
        <property type="entry name" value="BipA_II"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047043">
        <property type="entry name" value="BipA_III"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035651">
        <property type="entry name" value="BipA_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035647">
        <property type="entry name" value="EFG_III/V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000640">
        <property type="entry name" value="EFG_V-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004161">
        <property type="entry name" value="EFTu-like_2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031157">
        <property type="entry name" value="G_TR_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005225">
        <property type="entry name" value="Small_GTP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000795">
        <property type="entry name" value="T_Tr_GTP-bd_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009000">
        <property type="entry name" value="Transl_B-barrel_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042116">
        <property type="entry name" value="TypA/BipA_C"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00231">
        <property type="entry name" value="small_GTP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01394">
        <property type="entry name" value="TypA_BipA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908:SF8">
        <property type="entry name" value="TR-TYPE G DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42908">
        <property type="entry name" value="TRANSLATION ELONGATION FACTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21018">
        <property type="entry name" value="BipA_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00679">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00009">
        <property type="entry name" value="GTP_EFTU"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03144">
        <property type="entry name" value="GTP_EFTU_D2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00315">
        <property type="entry name" value="ELONGATNFCT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00838">
        <property type="entry name" value="EFG_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54980">
        <property type="entry name" value="EF-G C-terminal domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50447">
        <property type="entry name" value="Translation proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00301">
        <property type="entry name" value="G_TR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51722">
        <property type="entry name" value="G_TR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tr-type G" evidence="3">
        <location>
            <begin position="84"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="664"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00021392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2434942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="683" mass="74322" checksum="DC0E8E1E8DDA8A52" modified="2021-09-29" version="1">MQALQKIQRQAQRQASAQAPLRVEAPVVNRAVLSAAAAPVAAAAPLPAARRTVALGAPARPTTVCRTATVDAPASTSSEGSVREDIRNIAIIAHVDHGKTTLVDAMLKQSKVFRENQATAERIMDSNDLERERGITILAKNTAIRYRGIKVNIIDTPGHADFGGEVERVINMCDGVLLLVDSVEGPMPQTRFVLRKALELQKRVVVVVNKIDRPAARPEWVIDSTFELFMDLGASDELCEFPVVYASGVNGIAGMTPDGLAEDLEPLFATIVKEIRPPVVKSEAPLQLLCANIDYDEHKGRIAIGRVSSGTIKRGQSVSICSSLEPGKVRQAKIAELFVYDNFSRVPVDEVAAGDICALSGIADIKIGETITQREAPVPLPTIKVEDPTVNMTFKVNTSPFAGKEGKFVTSRNLKDRLDRELERNLALRVEPGETSDSFVVSGRGTLHLGILIENMRREGYEFEIGPPKVITREVEGKTCEPYEEAIVDVPEQYVGAVVELFAQRKGEMVDLIPSIQGASRIKFRIATRGLLGLKNQLLTATRGLGVMNTLFLEYAPVAGEILMRENGSLVAHETGQATTYALESAQDRGQMFCRPGDQVYEGQVIGMHAKAGDLKVNVCKTKALTNMRAAGKDTKVGLDEPRTMGLDDSLEYINDDEQVEVTPKSIRIRKDPMASTKGKKGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T226</accession>
    <name>A0A835T226_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013458</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000075">
        <property type="protein sequence ID" value="KAG2431025.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T226"/>
    <dbReference type="OrthoDB" id="537650at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="539"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="541"/>
            <end position="559"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2431025.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="663" mass="73068" checksum="E24B88810840EB2F" modified="2021-09-29" version="1">MRCRRASEKHIISALPALVVSALIKTGRSYTLRNVVPAVLAEVLRSQPPDHPLQGIKVLQLNGLDVRREAGAAVLLYDLLRLVVRWAATAGVPVKAAAWREALEVLADDTGSPGMCMRAGSALVAVLHGFEAPVLVLLDELQALLQPTVPRGGEQPLGVEGAGYIRDNVLRAILVDSPPSMLLAVTGSSMALVWTALGAMPVNGVAPLYQVHQVDLPSKSPPGAMERLLEHSLQRWRLQQHRKQVLRLLERAGDSPALFMTMVDRWDAAARPKNTDAFADAYIRSKLFREAQKEWMLGLAHWTDADRGRLLDMADPLIGADFEQDGIVDPSLWRFLRPNLKKTYSGRYYLADFTQRQLLRAVIDRGGKLRKSWTGLVGPGLTLAQLDFGWLLLHLGEVADYLLGLRRRPDINPDRIRGVKRLGKLLQDLATKAEEKLPPGDSVADRWEALNAFKQVLDSPYNAGSRRWYQDEGRGRKLKSHRDLLVFFLRPSDRRKRVAVNTVMALPALLDMPVLELAEQVRSGMSRLAPVTIKDAAAAADAEDEEWEEFEEGEDEDEYEEELEEDEWEELEAWGGGEKGSGRGGRAGGAATVCAIFGGRSANRSGCQISSSPWPPLSAPTLGRRSGPVAIRRTATAGVLLRANAHIHRVRVTAAYQAPPLIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T354</accession>
    <name>A0A835T354_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Phosphodiesterase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_011675</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000050">
        <property type="protein sequence ID" value="KAG2436172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="568146at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006189">
        <property type="entry name" value="CHASE_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01079">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50839">
        <property type="entry name" value="CHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="7" id="KW-0472">Membrane</keyword>
    <keyword evidence="1 5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="46"/>
            <end position="68"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="337"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="domain" description="CHASE" evidence="8">
        <location>
            <begin position="147"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="domain" description="PDEase" evidence="9">
        <location>
            <begin position="883"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="738"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1100"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1254"/>
            <end position="1308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1331"/>
            <end position="1362"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1391"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="744"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="802"/>
            <end position="813"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1100"/>
            <end position="1113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1261"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1286"/>
            <end position="1295"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1331"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1401"/>
            <end position="1410"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="958"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="958"/>
            <end position="962"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="962"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="999"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1000"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1000"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1000"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1161"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1161"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1212"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2436172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="12">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1410" mass="146791" checksum="00825C3DC9331ADF" modified="2021-09-29" version="1">MRNTEKTARIKGKPITGSFQDASRAAHTCARESKALWALIKSYPSLGLIPIALLAVLLAGGLTAVIYVKNSEVKVAKERAASEARDSATWFQQQVQLTLAPVLTMASMVQSQPQYNVVRGWFPALSESLVNNSQAAPGALIALQLVPHGVLTMVYPRSPINLRSLGTDLFNSTSTNPAAARLAMTRRRLQVLGPLRTEVGWYGLVVFMPIFVSGVDANDTFGIAVPWSSNCGAPCAYNATTRTAAWGMVVAAVDLPTISSAQQSDVRPLFALNYNYEIEALPSTSGTIGAAQPSTRPEDRFVMRSNKRPVDPVEAYIQLPDAQWVVRVAPEGGWQPGWYGGLIAAVVILSVIISLLLFAAMVAWRRHQLLLEALLPKEVIREMQVDEAVSLGARMIQTTDTPADLLLKMMGDLLQGRPPELRDVVFIRTALLRNADVYQPLNLRGRLKEANFDADVMQALMNQLGAHGAGSDGPSLCSEQLTAAGGGDCNTTGQLTGLSLSKIDAEDAAGGDSSPFFSANAATTHGAGTTVGNTGSSHAQQLKFDTLAAALAALLAPQLPLGPPPPAAPLPLLGQPSSNGPAIAGAVNTDAPSATAADARFSLVAAVGSNVPPVVDILSTGGAAVSGSHCCQNAANAGNALNLPPVPLPAEPFVIESQEVNFAAGGGWLEPALPSGQLLRNKTSNGVLTVAAGGAPAAGVLDGIAGGGSGGAGPSSTGSPGGGGLIARLAAALPLIGYNHNTHSSRERDGGDGKERRRAARETARGGGRVGDPLAAALAADEDPFGRMSDSRVGNMGAALSGAGGGGANGGPRSGSAASPPRISMPGGGALGPPVRHLTSNLAGGPVSSGARSGTLPTCQLSRGMSHATSGQHLAPAAVVVMPPPPVIEEVERLLAGADAWTYDTWKLAEATQGHALSALAFYLMHREGLISKFNIKPAVLARLLRALEAGYAPNPYHNATHAADVLQTLHVLIHASGLHVHYLDRLGLLAAYFAAIVHDHNHPGLTNDFLINTNDMLAIRYNDKSPLENHHTASCFGLMALQPELDALAPLSQPEKAAFRKQVIEMVMGTDMKQHFATLAHFNTVHRLASYSRESGSVRSSAAGGASPVAPGAKGGLGGAKTKKSLQQQPAEALPAEVAPKPLDDTERMLTLQVALKVADIGHLGEEIEVHKRWLGVLEEEFFNQGDRERALGLPISPLFDRTKQGVSKSQVGFYDFVGLPLVHAISSAFPGAKPIFACFAANYEHWKVVEQQQQQQQQAATKSPSSPVNATVTKPPLPPPSRPQLPAKQQQPQQQPPHLPTTQQAAVAGADEVVVELRSGASMSACVDASSGSASGSIAAGGKPGAPAHVSPTPRSADVTAPTGVAARKSMHTQVSRSRFAVATTPAAARTGLEADDGQLTQSSEYDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T3V6</accession>
    <name>A0A835T3V6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">MI domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_013321</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the eukaryotic initiation factor 4G family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000073">
        <property type="protein sequence ID" value="KAG2431330.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="514777at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016281">
        <property type="term" value="C:eukaryotic translation initiation factor 4F complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003743">
        <property type="term" value="F:translation initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.180">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003891">
        <property type="entry name" value="Initiation_fac_eIF4g_MI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003890">
        <property type="entry name" value="MIF4G-like_typ-3"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23253:SF9">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 4 GAMMA 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02854">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00543">
        <property type="entry name" value="MIF4G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51366">
        <property type="entry name" value="MI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0396">Initiation factor</keyword>
    <keyword evidence="3" id="KW-0648">Protein biosynthesis</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MI" evidence="5">
        <location>
            <begin position="1545"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="397"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="473"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="584"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="684"/>
            <end position="740"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="812"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="971"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1194"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1399"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1462"/>
            <end position="1496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1522"/>
            <end position="1548"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="74"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="154"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="191"/>
            <end position="218"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="243"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="303"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="397"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="591"/>
            <end position="608"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="609"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="706"/>
            <end position="715"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="717"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="816"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="871"/>
            <end position="883"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="893"/>
            <end position="903"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="971"/>
            <end position="1008"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1009"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1201"/>
            <end position="1224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="1241"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="1251"/>
            <end position="1261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1415"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="4">
        <location>
            <begin position="1479"/>
            <end position="1489"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005775"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022540"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS51366"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2431330.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1754" mass="180358" checksum="F76D0CFBC9D90364" modified="2021-09-29" version="1">MAGRGPPSGGRGGGRGQAGGRGQHPNAAKKPQDNGGAAEKPAQQQAGSAAAEASAKPAGAWGSGPSFKEKLLMAQKQEAAAETAAAAAASAGSNQPPKSAANGPEAGSTTADSDIQFGSFAETEGSEVAQSKEQPAAPAGPLPTAVPAAVEAVRQQSRQVIRTNSAPASANPAQEGAREGPVFVPHKVERAPQQPSRMAAAAAAPAQVEGGAQAQQPPMQAPPPSGAPEAAPMQAAVGGPRDTSVQQRQGAHNRQVGHDRQQQPHAAGPMPYAHATGAAVSVGPGGGAAPHHGGPRHGVHPMHQPPPPPHQQQQQQPPPPPQPQQQQQGFGPGPAGQPPQPPHHHMQGPPPQPVGPRGGPGGRGVPPPPQPVPVAMPVQVPVQGGYPQGPYMAPYGPQPTAPMNMPPQPQPHGYGAVPGQGMPPPPPPPQQYVVGSPSQYPPQFMGAPQFFPPGAVIAGPNGPMPIGIMAVPIPPPGHPAHHHGPPGGPHGGPPGHIMASSPTMGFHVPPQHQHQHQHQHPHPPPPANYGPGPAGPQSAAMPMPMPPSVPNASSGAPNAPVAAAAQAAINATNAAAPVPAVPTVVPAAQPHHPPPSHVPAPSPAPAPVPSAMQTAGAVPSGAGAQPAAPAAAGPAAAKPVATPPPPPAKKVLKIVDPSSHKEVNLSGSAAPAAVPATTAAEAKPADAAAVPPKPATVPGVQAPPKKVLEIKEPTVRPKATASEAPKAAEPPKPASAEAVKPAEAPAAAAAPASAAPAAKPVASAFAEAAAIPAKEPASFQIDVADDEEGDEAKAAVGSTAAAAASEEAGAASGAGAASGSGSGDDGASGGAAGSRKKNLKQALRDADAKGANNDMLSAFRGAPPPPPPEAAKPKEVAAAKEEPAAAAPTAEEVTEHWEERADEAAEASGSGGGDANDKRHRYSRDYLLSIGSRILDPLPIALDSYHQQNIGLEKPQDNTRIGVGLTLGRAGSREADWGRRDERNRSGDFRGGDMRGGDMRGGRDRDGMRGGQGGRGGGGMDRRGSANMDDGWQRRGPPPPPSPGGDMQRGGSRGMSRQGSANPAYGGGGGPVNLHKTENRWQAGMSIAEDPEEEKKQKTFKGILNKLTPDNYEKLKLHILAVQITHQKTLEGFINQIFDKALIETTFSEMYANLCKEIHPSLPTFPSNDPSSNKPVDFRRMLLNKCQQEFEDGTAAMQKVKAREEHDKEEAEKKLHEKEKKEDTVAAQGENGQSQLEEGEVAASSSAPSAEDAKAKAQAEAAEAERELKARRRMLGNIQFIGHLYKCGLLTERIIHSCIVSLMQDTKSPRPDDIECLCKLLTTLGKQLEEQTAKKMQQNQNPMEVYFKRLRDLRESSNLDSRIKFAIQDVLDLRAAKWVSRRKAEGPKRIEDVHREAQAQLAAQASRDREERYGGQRGPGGRGGPMGGRDAPPPPGRFGGPPQQDEARLMGRGEVARPLRAGGMERQASSEVSLRPVSSAFSSKRTGSPAQPAGGSVAVSAGAAREAAAAAARATAPVAAAAIAASREEPRAPPPPPPSGMSEEAAKKKGSSWCKELYEVKEKAAAAESLATFKSDGAPMGVLLAAAIREAFEVRGIAPAERLNLLKELLVEQLTAADGVLTSSMLEDAFARFMGDLHTWVEDNPKAAGVAGSAVGELAAQGHLSLGPCLRPILEAKGSGAADDDEEGGDEDLPPLVECDAAADIIKHVLESATTVNADKVADLWRASGLDVKVFFAMPEDADELSGKYSWLSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T3W0</accession>
    <name>A0A835T3W0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_010990</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000044">
        <property type="protein sequence ID" value="KAG2438293.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T3W0"/>
    <dbReference type="OrthoDB" id="560453at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="128"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="221"/>
            <end position="233"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2438293.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="241" mass="23489" checksum="D62B95FBCCA8573F" modified="2021-09-29" version="1">MSTPASPARGSAPRGDVETKNDDADAVIGPPTPAAVAGSKRKACDAAPGTAEMPPPGPAVSDGSPVPELDAPRKRAHITGLKGEASAFADGPESPPPKQPEQEQRTQDAFPAGAEAAEEQMGPASGVLPPPPLPPPQAAAAMAPDSPPQDAAVAVAAVVAVGSQVPTSLGPALADAGAAAPPGPCASSAGAAVHEKPATAPAAAAAAATDQPWLPPPASLPPEQEQPQQPLQAEKGDEVGE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T466</accession>
    <name>A0A835T466_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">hydroxyacylglutathione hydrolase</fullName>
            <ecNumber evidence="5">3.1.2.6</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">Glyoxalase II</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_013404</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>an S-(2-hydroxyacyl)glutathione + H2O = a 2-hydroxy carboxylate + glutathione + H(+)</text>
            <dbReference type="Rhea" id="RHEA:21864"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57925"/>
            <dbReference type="ChEBI" id="CHEBI:58896"/>
            <dbReference type="ChEBI" id="CHEBI:71261"/>
            <dbReference type="EC" id="3.1.2.6"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="3">Secondary metabolite metabolism; methylglyoxal degradation; (R)-lactate from methylglyoxal: step 2/2.</text>
    </comment>
    <comment type="similarity">
        <text evidence="4">Belongs to the metallo-beta-lactamase superfamily. Glyoxalase II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.2.6" evidence="5"/>
    <dbReference type="EMBL" id="JAEHOD010000074">
        <property type="protein sequence ID" value="KAG2431271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T466"/>
    <dbReference type="OrthoDB" id="515692at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004416">
        <property type="term" value="F:hydroxyacylglutathione hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019243">
        <property type="term" value="P:methylglyoxal catabolic process to D-lactate via S-lactoyl-glutathione"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd07723">
        <property type="entry name" value="hydroxyacylglutathione_hydrolase_MBL-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.15.10">
        <property type="entry name" value="Ribonuclease Z/Hydroxyacylglutathione hydrolase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01374">
        <property type="entry name" value="Glyoxalase_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035680">
        <property type="entry name" value="Clx_II_MBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050110">
        <property type="entry name" value="Glyoxalase_II_hydrolase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032282">
        <property type="entry name" value="HAGH_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017782">
        <property type="entry name" value="Hydroxyacylglutathione_Hdrlase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001279">
        <property type="entry name" value="Metallo-B-lactamas"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036866">
        <property type="entry name" value="RibonucZ/Hydroxyglut_hydro"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR03413">
        <property type="entry name" value="GSH_gloB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43705">
        <property type="entry name" value="HYDROXYACYLGLUTATHIONE HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43705:SF1">
        <property type="entry name" value="HYDROXYACYLGLUTATHIONE HYDROLASE GLOB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16123">
        <property type="entry name" value="HAGH_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00753">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF005457">
        <property type="entry name" value="Glx"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00849">
        <property type="entry name" value="Lactamase_B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56281">
        <property type="entry name" value="Metallo-hydrolase/oxidoreductase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0862">Zinc</keyword>
    <feature type="domain" description="Metallo-beta-lactamase" evidence="10">
        <location>
            <begin position="22"/>
            <end position="186"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001623"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004963"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00006759"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00011917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031044"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="SMART" id="SM00849"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2431271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="271" mass="28982" checksum="776ADD9BAF562E6A" modified="2021-09-29" version="1">MGAPTSGAAGVMEVVRVPCLSDNYVWLLHEVAPAGGGAGRTAVVDPAEEGPVVEALAARGWTLDAVLNTHHHADHTGANLALKRRFPGLMVVGPRADKDRIPAIDVQVGCGDTWHLGGLEVRVFDTPGHTRGHITYYVPQAASLFPGDTLFALGCGRLFEGSPQQMWASLSKLTPLPDDTLVYCAHEYTQSNARFAVTVDPRNAALAQRKAAIDAARAQGEPTVPSRLGEEKATNPFLRPHDPAIRQQLGFDAAAPDWQVFGAIRAAKDRF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T4Y3</accession>
    <name>A0A835T4Y3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_006541</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000041">
        <property type="protein sequence ID" value="KAG2439012.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T4Y3"/>
    <dbReference type="OrthoDB" id="5952569at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2439012.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="421" mass="44545" checksum="5A79BD92FB1AEC22" modified="2021-09-29" version="1">MKGVFQKIGSLRTTGRGPSADGAGGEPGQQRGSSVTLSIVDQHVARLKQAEEARKAREALLTGLKPFVLDNTLVECLSTGGETLEDKLEALKLTRSCGLQNVVLAAFVKERTPDLQFLQALRSSKLIDEHCFAFSELYDANGSDLPGQDLPFGLAKMIQYGIQNAILEVDVAATYINWEKYHIEDLCSLVESRCRWVAANLFAGRPTQPASYVHLRDFAVSMQTAPARLLTLVESLARLDPAVRPRGLFINQPAPGQFPFEAAPCVAAVRGVMDGAGWSEGLLVVHVGAAPGYGLAHATVLECLAAGCSGVMAALCEEDATSSHASSLLDLVNLARLGNKHVSERFQLDRLRAAAKEVSAIMERAKAQLLQQPAAGAAAGAGAQRGGAAMTAVQPLTGSPGKPLPHAIPATEHKPLIPGHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T693</accession>
    <name>A0A835T693_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_010568</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000040">
        <property type="protein sequence ID" value="KAG2439687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="429991at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051291">
        <property type="entry name" value="CIMAP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010736">
        <property type="entry name" value="SHIPPO-rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580:SF28">
        <property type="entry name" value="BOREALIN N-TERMINAL DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21580">
        <property type="entry name" value="SHIPPO-1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07004">
        <property type="entry name" value="SHIPPO-rpt"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="89"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="140"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="391"/>
            <end position="410"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="434"/>
            <end position="475"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="499"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1497"/>
            <end position="1553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1725"/>
            <end position="1801"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="89"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="532"/>
            <end position="542"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="716"/>
            <end position="732"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="902"/>
            <end position="911"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="940"/>
            <end position="950"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="965"/>
            <end position="975"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="994"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1099"/>
            <end position="1116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1331"/>
            <end position="1350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1362"/>
            <end position="1377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1378"/>
            <end position="1399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1408"/>
            <end position="1427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1497"/>
            <end position="1515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1522"/>
            <end position="1541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1753"/>
            <end position="1784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2439687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1801" mass="183256" checksum="65AF9593E0383FEB" modified="2021-09-29" version="1">MPSKSAKNKFLTTTGDRTVDGWVSQAQGPAFGQPFKFGADLTFTRKAPTYLTDMQLHTLAYLDPAAASLQRSLREPRAAPTVAATVVRHGGGGVGGGNGSSLGGSASGGGSAARAAAARQHQHHQQYQAEGAPHLVVARHPSGYYSHGNSQNVPPAGSYEGGGGGGGGAIGGGGGGADGTSTAGGDTMALAAGFMTGMAPPPPPPRGATVSRAPVVLPHGGRTTKATGMVLREWGSLYPQAWADSAAAPPPLLEGMVVVERQDAADKRRAAAGMRPRRPEGHVKGCRCNECLAVTAALAALAASTRRSGSGRGGAGSGSGSIFLDEEASEEGDTPGPGQYEVTKVGGVGRSGPAFTMRGRTVPPGAALANPEAAKVPGPGAYDVPRPVAEGPAFTLKGRPKAPSSLPDDLPGPGEYFVETQMREGPAFTLAGKPKRKLETDSPGPGTYVVSEPVNTGPAHTIAARPKPRAPEQLPGPQDYQQVLSPGREGPAFTIGGRLEQKVDTDVPAPGDYDLPNAWKTGPAVTFAGKPAPRPDPEPAPGPGQYYVPPRPGQDLPAYSFGAKPADPQPDDLPGPGTYYKPLGSPGPAFTLAGRPAQPQPDPVPGPGAYDPEDPVSPGRDGPAYTFGGRLAERSPPASPGPGAYRPEEVGSPTGPAYTMATRPLDREAPDSPGPGAYQPQDPALAPGPAFTMAGRPVERDPRQDLPAPGDYHTEGAAAAAAGGPCSPSGPAYTMRGRPLEERVPLSPGPGQYSSPAPPRGPAFTMAGRPAPPDPESPTAHSPGPGEYDVASPAPTGPAFTIGGKPHERAAPDSPGPGEYSRPASPSGPAYTMRGKPAEPAPELPLVGPGAYDPEKPLPDGPAYTLRGRPREPERPPSPGPGEYEQRDEDRGPAWTMGTRPPDPRDADEGRPAPGEYDLPASPTGPAYTMRPRPPEPRNEANPGPGEYASPAPPSGPAYTMRLRPPSPERPPSPGPADYQRLAGPTGPAYTIKGRHEECKVYDIVDDPDIPGPGFYGNPDPDPMGRSGPAYTMRPRYQPRPPADLPGPGDYVAPSGPTGPAFTIAPRYPASPSGGTEDEPGPGAYAPPVRPDGPAYTIAPRFADPAPDATPAPGEYGSPGGGPSGPAWSLGQRVPDPAPDSNGLGPGEYYSPGLPSGPAYTMGAKFKSRKRTGPDPGQYFKMPPPAGPAWTLGPRTAGLSPDRPDVGPGDYDDNRDLHSGPAWTLRPRHASPTPDPVPGPGFYNDSKPFPNPLGTVISRPRAVGERDGAYLTTDFGDPHAPTMSPTVSPGRPGRKVTFTSDTMFRDSMDMTYGGRVRQVEPTVSGPGGAMVPPPRGAPAAPVMPPPPPPRESGGSAGTSYPHYPPRQPAAAAAPPPAAAQQQPADMAVAGQGARGVGRSASRERQQRGARAAAGRQGSAAGAAGPARADARDAAVDRAMALLRQDMLQQRYLYAGGPPAGGEWEAMILARGVPGGGGGGVAFAEEGIAVGDVVGPGRQRPAAAAAGQQRAASAGRQRSKGIQAPQQQQQQQQQQQQRPARQGVSDTSGGFPFQRPVTHAQQERYVAGLQAQRAAGPAVEVHVLEPPAPPPPIPHTAAEAEAAAAAQRVAGRAALQMAAMEGRTAEGLGGPPAMTQGPLGVPVARARRRLEMGGPGGPSVVGLSPREAALARAAAYMGRRAGGAGGGLVVGGTELVAGAGALDAAAAAGREAAAAAAVVRPSVAVQAAPEHAPRNPKVMTAPAGRLVGGGGSSRPGTSTSGAPTSTAATSLSSKSTSTNKSKGGAAVRPPSLGRQLVREARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TB11</accession>
    <name>A0A835TB11_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GrpE protein homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_009679</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Essential component of the PAM complex, a complex required for the translocation of transit peptide-containing proteins from the inner membrane into the mitochondrial matrix in an ATP-dependent manner.</text>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homodimer.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="7">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 8">Belongs to the GrpE family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000033">
        <property type="protein sequence ID" value="KAG2442192.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TB11"/>
    <dbReference type="OrthoDB" id="201635at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000774">
        <property type="term" value="F:adenyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042803">
        <property type="term" value="F:protein homodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051082">
        <property type="term" value="F:unfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006457">
        <property type="term" value="P:protein folding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00446">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.22.10:FF:000001">
        <property type="entry name" value="Protein GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.20.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.22.10">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_01151">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000740">
        <property type="entry name" value="GrpE"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013805">
        <property type="entry name" value="GrpE_CC"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009012">
        <property type="entry name" value="GrpE_head"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF010741">
        <property type="entry name" value="PRK14143.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237:SF40">
        <property type="entry name" value="CELL CYCLE AND APOPTOSIS REGULATOR PROTEIN 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21237">
        <property type="entry name" value="GRPE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01025">
        <property type="entry name" value="GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00773">
        <property type="entry name" value="GRPEPROTEIN"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58014">
        <property type="entry name" value="Coiled-coil domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51064">
        <property type="entry name" value="Head domain of nucleotide exchange factor GrpE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01071">
        <property type="entry name" value="GRPE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 7" id="KW-0143">Chaperone</keyword>
    <keyword evidence="9" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0346">Stress response</keyword>
    <feature type="coiled-coil region" evidence="9">
        <location>
            <begin position="29"/>
            <end position="84"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU000640"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU004478"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2442192.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="221" mass="24006" checksum="C76D8F5DC36FED28" modified="2021-09-29" version="1">MKAAEEAEAAAAPAEAVPATPLERVKHALESETLDKDVLTAALAELEAEMGRLQSAASEAGDRAKSLEASVASAKDQYLRLNADFDNFRRRTREESAALTDSVRGDVIKEMLPIVDNFELARTQVKAETEAEQKINNSYQGLYKQMVDLMRSLGVEAVPTTGTPFDPNIHDAIMREPSNSHPDGTVLQEFRKGFAIGGKLIRPAMVKVSYTEEGPAASSEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TB29</accession>
    <name>A0A835TB29_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Peptidase M14 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_010494</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 3">Belongs to the peptidase M14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000039">
        <property type="protein sequence ID" value="KAG2439863.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TB29"/>
    <dbReference type="OrthoDB" id="10253041at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004181">
        <property type="term" value="F:metallocarboxypeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd06234">
        <property type="entry name" value="M14_PaCCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.3120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.630.10">
        <property type="entry name" value="Zn peptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050821">
        <property type="entry name" value="Cytosolic_carboxypeptidase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040626">
        <property type="entry name" value="Pepdidase_M14_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000834">
        <property type="entry name" value="Peptidase_M14"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12756:SF11">
        <property type="entry name" value="CYTOSOLIC CARBOXYPEPTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18027">
        <property type="entry name" value="Pepdidase_M14_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00246">
        <property type="entry name" value="Peptidase_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53187">
        <property type="entry name" value="Zn-dependent exopeptidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS52035">
        <property type="entry name" value="PEPTIDASE_M14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase M14" evidence="4">
        <location>
            <begin position="188"/>
            <end position="479"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor/acceptor" evidence="3">
        <location>
            <position position="443"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001947"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005988"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU01379"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS52035"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2439863.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="483" mass="51155" checksum="872FC31662C29BC3" modified="2021-09-29" version="1">MSCRQLTRASAGWMLDRALPSAQLAASALRSATARDCGHRRLHIGRAAAAAAVHATHTPAAAAALAQHGYHISSAMDAGNIEVVGVSDGGKAIDLNIRPDPYCETDKRAHYQWFHFKLAGVAGRELSLRLLNAGGASYGPGWEGYQACASHDLEDWYRVPTAYDAASGVVTITHQPGAADVVHYAFFAPYSLDRHAALLGRLQRAALPAGGPAAGGSAGGSAGPAAPVRVRVLGSTIDGRDIDLVQVGPSTSASPPPSNGTAPLLRVWVVARQHPGESMASWFAEGLLERLTDPQDGVARRLLEKAVFYVVPNCCPDGSFRGHLRTNAAGVNLNRTWADPHPAISPESFHVRNEMDRTGVDLFLDVHGDEELPHVFVVGNNGIPAWGPRLEGLQAAFCDAFKRHAPEFQTAKGYPLDVANTANMGIASKQIGQRFGCLALTLEMPFKDSADLPDPRVGWSGGRAKRLGAAVLGAILEVAPQLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TB40</accession>
    <name>A0A835TB40_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Wax synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011362</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000047">
        <property type="protein sequence ID" value="KAG2437104.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TB40"/>
    <dbReference type="OrthoDB" id="548170at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008374">
        <property type="term" value="F:O-acyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006629">
        <property type="term" value="P:lipid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044851">
        <property type="entry name" value="Wax_synthase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595">
        <property type="entry name" value="LONG-CHAIN-ALCOHOL O-FATTY-ACYLTRANSFERASE 3-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31595:SF57">
        <property type="entry name" value="OS04G0481900 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="30"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="55"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="381"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="136"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="147"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="210"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="220"/>
            <end position="247"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2437104.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="449" mass="47544" checksum="424D10898D7921F3" modified="2021-09-29" version="1">MTTATPKAGGHKAGRLHDNAGSAASLASRWVAKLVGLGLVVATITLRGSALPRVLLHYLYALGLYFFVGFLMDGPGAVAVEALGLQLVPTFDAPWLSTSLADFWGRRWNITTSSVLRTLVYDPLAEGRLVATRHEAPGEPAEVHRQQQPHHRHHHHHQQQQQHTAAMLETTLRAHGEAPEPACTGLLAASSLIALGPPSSVSGRPSEAVGGHDDSDAHASAHASESGSFASSSHSGRSSLSESGSGDCDPRHPDAGTTHRSSEMAPDEPAPAREAPHHGAKPQPPPSEPCEASNPGALAASTSTAATGGVWAPGSLLRRTLAVHACCLASGLCHEYAIWHVSGKSWHWKWTLFFYMQAPLMTLEGFGRRWLRRRGLRVPRLLANALTLAVLEATAYPLFFGFVETDTDLAKRVVAAVSHNYQEMLQPLRPLLASAAAALAGGGSAGAEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TD79</accession>
    <name>A0A835TD79_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_009344</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443274.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TD79"/>
    <dbReference type="OrthoDB" id="418595at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="7"/>
            <end position="43"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2443274.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="176" mass="17209" checksum="DC80774DD7DA7FD3" modified="2021-09-29" version="1">MAGVARAAAGAKGGPRWRGAHACRGAANGGSGEPTRAVPHPDDAGALRREVTRPGVWFTYILCALGADMYGRGFTLPALLAAPYIPAAAGSAGAAGPAVLTKLLPGWVLAGAGEQLAGASGAGRGNGLGLGLGAGGSRLGGFVSALKAPAMSWLWGVAAGALIEVILLARLPVPPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TD99</accession>
    <name>A0A835TD99_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009371</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TD99"/>
    <dbReference type="OrthoDB" id="543916at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039715">
        <property type="entry name" value="ZCCHC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491">
        <property type="entry name" value="ZCCHC10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491:SF0">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032703307" evidence="2">
        <location>
            <begin position="28"/>
            <end position="619"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="43"/>
            <end position="82"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="101"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="126"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="217"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2443304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="619" mass="63724" checksum="C633B7027437CAC7" modified="2021-09-29" version="1">MMAGGTDGRPSPAVPLLWACLLAVVLLLHLSLDLKGPDSGTYSIQTPGHAKPKASSSSSGGSSSSSSSRPGGPGARGDGTGSAAAAAAATSYSEAVGSAAAAGASRPSAKGASATALADGRERRSLSSSRSLATTTAAAGSISGGSGRVALELQLQLGLGPEVERELQRLGAQVADWDSYSPTLRSGGSSNGSSTHCSPSSSGGSSSSSSSSSSSSSSSRAAAAVRVGYYTRHTGTLWDWMAVAGALALDWERRNPAWWYAKYGMSADTAAAIWAGNGTRTLCPPQYDVLVYCDTVVDARPVLQRLVAGGGGGGQGGGSGREGGEAGGGCDKPIVLQVTNRFDWKVRDTGAYLGLMRAAAASPRVWQGLELPPQRHLMLRPVGAAVLPPPPLPAGGSGGGGLDRSSTFAVVVKGNRAKHPDRDVLLPQLRRLGLMPSRSGGSSSSSSTAGGRIGQQALVHVYDRQYGGPAALAQHRGVVHLPYQMSIMGMYELLAAGGVYLLPSPGFFRQLRQKHRFATAFVPLLSRAAVRRRDGGRLNWTAYVEWYHPDFEQAMVYWDSWEQLQELMARPPDDPLWAAKRAAARAAMGRVRAASLQGWRGVLGQAAAAACAGAGGGGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TDW1</accession>
    <name>A0A835TDW1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011611</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000050">
        <property type="protein sequence ID" value="KAG2436100.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TDW1"/>
    <dbReference type="OrthoDB" id="550288at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004969">
        <property type="term" value="F:histamine receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003980">
        <property type="entry name" value="Histamine_H3_rcpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40430">
        <property type="entry name" value="T. BRUCEI SPP.-SPECIFIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR40430:SF1">
        <property type="entry name" value="T. BRUCEI SPP.-SPECIFIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01471">
        <property type="entry name" value="HISTAMINEH3R"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="159"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="783"/>
            <end position="823"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="24"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="55"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="166"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="259"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="294"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="333"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="344"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="372"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="411"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="427"/>
            <end position="454"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="455"/>
            <end position="472"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2436100.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="855" mass="84988" checksum="D358B2F57722F7A8" modified="2021-09-29" version="1">MDPEDAPLAAPETADPTMGAAEEQTLEDPVEASAAGDEDAVAPGTGADAEEEPAADASEPAADSYAEDDFHEHDEAADAAEPAEEPEAPAPDAAGPSGADEEAAAEAAEGRDEMLEPNGKILTYISPSFQRAASAVYKIQADPEELAEAKEALLAGIASTGPSRNASSVARAASGSGSGAAAPAAAAAGSASSAASKQASFSSQAASASGAAPAAGGAAPAPGSAAGSQPASKAGSFTSAAPPPAASASSASLGGGAASRGASFSSAAPAAAPEASAVSATSSSLKRQQSGGSAAAAAAAVAAGEGPQPSAPSASGAPSGAASRATSFVRAGQASQSQRTGSRPGSTEPPESSAPSTSSVAPPPPLPPRGQSAASTASGVRRAPSTSSSAGQPGAEPSLAPAAPPAPAPAYGPAASSPAYALPPLPGSAAGSRPRSAASASASAADPAAAAASPQPSPPPPAEPPSPPPPPHHLSTTRVQPKGPLDACAAQSASEHVRSVWSTANICGIRSLPNALSPDFRERLYQELVAAAQRERAGDTSGDRGRRADLSYGLEGGPLAMPLSVGQKQVARIHPLRGMFTQYEYLPSEYDRVKLMGKFDRLKHKLSQATPSEFVVRAPPVPPRGAPAFSEYAYVVDPAEAYDSSVLADNDVGRSKVVAGPFYPAGRPNAITSLKGRLDECMMGLCRQLSEDWPTGFLQIFEDANGSVVVSFDKARAVSEGDLTSYMNTLAKRHHLVAAFHLLKDATQWGLVDADTGAVFYVLWPPWVRHKYLGPHAAAAFGETANGRPGTRGSDSSDEEGGGGGDGAYDGEEGPRSGGGLLESYGDGASLGLVSTATGMANDGYGRMGSAMRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TIB5</accession>
    <name>A0A835TIB5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">S5 DRBM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_010944</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1 5">Belongs to the universal ribosomal protein uS5 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000044">
        <property type="protein sequence ID" value="KAG2438245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TIB5"/>
    <dbReference type="OrthoDB" id="309483at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990904">
        <property type="term" value="C:ribonucleoprotein complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005840">
        <property type="term" value="C:ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003735">
        <property type="term" value="F:structural constituent of ribosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006412">
        <property type="term" value="P:translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.230.10:FF:000002">
        <property type="entry name" value="30S ribosomal protein S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.230.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020568">
        <property type="entry name" value="Ribosomal_Su5_D2-typ_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000851">
        <property type="entry name" value="Ribosomal_uS5"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005324">
        <property type="entry name" value="Ribosomal_uS5_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013810">
        <property type="entry name" value="Ribosomal_uS5_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014721">
        <property type="entry name" value="Ribsml_uS5_D2-typ_fold_subgr"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48277:SF1">
        <property type="entry name" value="MITOCHONDRIAL RIBOSOMAL PROTEIN S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00333">
        <property type="entry name" value="Ribosomal_S5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03719">
        <property type="entry name" value="Ribosomal_S5_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54768">
        <property type="entry name" value="dsRNA-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54211">
        <property type="entry name" value="Ribosomal protein S5 domain 2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50881">
        <property type="entry name" value="S5_DSRBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4 5" id="KW-0687">Ribonucleoprotein</keyword>
    <keyword evidence="2 4 5" id="KW-0689">Ribosomal protein</keyword>
    <feature type="domain" description="S5 DRBM" evidence="7">
        <location>
            <begin position="163"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="30"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="129"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="53"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="132"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008945"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022980"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00268"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="RuleBase" id="RU003823"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2438245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="354" mass="36713" checksum="107723243346FC78" modified="2021-09-29" version="1">MMPSLRSANSLHGSFAASAVISSPIATATASLDISQERGLSTEASGEGESEDSGLKHSNGDEEPPDRRRASDFEPGGRGGRDGRGGGGGGGGAFNPQTRRPGGSDAQAGPGLEMLELVATARELFTRDVAAGSGGSGGSGGGGVGPLPPLPRELREALYGHRWDRVIVDVRRTHTPVRGRGKDEEYTAMVATGNMRGVFGLGIGVAQSAQLATARAHLDSLGRLAAVPLYRGHTLYHHVDHSFHHLQMRLMPRPSGWGLRCPDLLYELCGLVGVRDASVRVRGQRKNKFFVAQCFLEALQKQTTPHDGVEATGMYIREVFRSGGGGGGGGGSANSGGGGGGALPCGLKRGVDVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TMK4</accession>
    <name>A0A835TMK4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_010346</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440465.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TMK4"/>
    <dbReference type="OrthoDB" id="10620873at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="43"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="208"/>
            <end position="234"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="414"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="462"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="584"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="58"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="77"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="464"/>
            <end position="476"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2440465.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="615" mass="61509" checksum="60CA310A5708A225" modified="2021-09-29" version="1">MQQLAAGRTLLAERPSARFAAPTRTGARLCRASAHKFPGFLGKIVSSGGKGKGKHRGHDHDHGHDDPSGMWQSQGHHWHDADSEAAPHLDGPAADYVALHPAPVEDDPFHPDLPANADAATAAAVWGPDMHGVLEVARPSAVGSGGAPGTRFVLAGAGGDAASQRHAALLAQLRERALEGSSDDDESWRRMDIPGLLLSPHHAAAIQSLSSASDSEDGLGGAAAAAGGPRARRRGGGWDGLLAPDFADLTLAREADAAAQAAAELVPPELRHLARAANILGVHSAARRGAAAGLGLGLALGLGGGAGSAASGEASGSEAGAELHMLEEANRFLGLPEEPLTPQQLEAAAALLLSSNNISPAGGLQSSWCVTGSVADTGFDADADTASDCEPGFAAAAAAVAAGDAALIGGNTVAQSARPARGSSGGADRAGSSSSSGSSTSSARAAAVAALSEEGIDWLGGPPAVAAATNGSSGAAAEEESRSVQLRRSPGPVGGVDAATRSRVAATVAGHVADAHAHVVRRGSTGTVPSSVDGERYQQQQRYSLTRGVVGAAGQEAADAAAAAVAAEARRAVWGEGGWPYDSAVRSTDVVEELKHEIQEQQEAAEHGSARLGLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TQ18</accession>
    <name>A0A835TQ18_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009343</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443271.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TQ18"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="26"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="91"/>
            <end position="101"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2443271.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="206" mass="20459" checksum="A012B34035C453BF" modified="2021-09-29" version="1">MAAALMLQVRQDAGHSGRVLSVHRQCTGTPHSQAPAPTCSPAASTSADRLAGIDNGGLPSDGCGTGGQNRGGGGAGGSGRAGKVSIDAASDGGGGGGGHSSGRGVGSDLLQALLWPVLALFAMFAFWFAFWTLGRSLEKAATTHGDSIKEAATKRGDSIEKAAGKLNWMAVIGGVSYAVTHLLVELLARRGGNGGGAAAGLRQAPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TRR1</accession>
    <name>A0A835TRR1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009574</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000032">
        <property type="protein sequence ID" value="KAG2443165.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TRR1"/>
    <dbReference type="OrthoDB" id="543962at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="283"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="12"/>
            <end position="29"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2443165.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="344" mass="35141" checksum="E9C93303964860EB" modified="2021-09-29" version="1">MRHGNLILSTEGLDEDQDDEEEQNDDEEQGPGKLLFGFEEEVAGSESAGPVELVVARAPAEGEAAERARASTLRGLAAGLAGGYEAAMVIEVKASVNYEVNIWQALAAGLELAQSNLRNGTSSPAAPVRVLLTDACKWYFLGLQALGGNGTAGGASAAAAASAPASDTVAASGAAGATGSAAAGSGKQGAQSGFEFTLASKGTFRLFDCRYVQADVLSPVVDFAPQLVQAMYCLYSAMYPDEDINGLPAAVAEGNRQAQQAGAAWLHGRSKLLTKLASPESALKAERARAAAAEARAAAAEARVADAEKARADAEKARADAAEQRLEEMNAKLAAAAAGKAEPS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TRT3</accession>
    <name>A0A835TRT3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_009284</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443210.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TRT3"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="20"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="47"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="64"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="78"/>
            <end position="182"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2443210.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="182" mass="21655" checksum="B6E10D23F280BBF7" modified="2021-09-29" version="1">MYNLDRSIVNGREISVTFSREGRKTPRDMMRIESKTKGDDRRDDRRRSRSRSPRRSSRRDSRSPRRSRSRSPRRSRSPRVDRGRDRSPRDRSPRADRSPRADRSPRDRSPHDRSPRADRSPVHAERERSPDRDRERVREDSRSPPPRERSPAPRDRSPAPRERSPSPRRDSPPRDDYAGDDF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VU31</accession>
    <name>A0A835VU31_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_014894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000111">
        <property type="protein sequence ID" value="KAG2425893.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VU31"/>
    <dbReference type="OrthoDB" id="528013at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.20">
        <property type="entry name" value="Vitelline membrane outer layer protein I (VOMI)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005515">
        <property type="entry name" value="VOMI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036706">
        <property type="entry name" value="VOMI_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841:SF0">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER 1 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03762">
        <property type="entry name" value="VOMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51092">
        <property type="entry name" value="Vitelline membrane outer protein-I (VMO-I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="197"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2425893.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1280" mass="135462" checksum="1EF6AFA0E5DA7165" modified="2021-09-29" version="1">MTDPPPSASGPPTPRAPPAIVASTWNASGDGNMRAPAARAGPSGQPPSAAASAPVTTAGLASPRSGYTAALLPPPFSARSRQASMSHPRPVAEGAEQDEGALVPVEDVADEHTAAVGGSGRSVRIERPASRAGPVAGAAVGVAGGGVAVADIAAAKGPSLKPSMSTANKVSPAPHYEQQHVTATSTATPSSATAPPLPPNDTDKVLNEFDVNRDQRLDANELAALVSKMVQEREDKRRLVWGLGAVLVVLVVLLGALTGMTWAVVAAFKDTDVKGGVMYVKGSTSEVVQTASSEMTIVGDDLQPELGECAPGRASACALINRQALAAVNTTTATAANANGTAAVLTQQPESVVRTATFVGTPIKFSSRVNIKQLMELKYLYITGMGEVEVALVVQGVARVPDPDSVWGTVVHIITGAGTITLDDTVIRFEEGIAPVFVKAGFIVSHSRRSLLGIYDVLGFFNFISDLEVFNLPPDQPKPSLPASNFMMRLKVYEPCVFPFDPTNDRCIAPPTDGAPNPDSRRRLLQQQQLGPLAPPSPSSPVLPLLASPDAPPSAAYAGAAAAAGPAAAGERRRRTLATAPHTHARLLADAGDAGAFLHDLAGVEVVNGSRYMTHTETALVWQGFMRTVYEYALFPAYRRVEVASNSSALMSVWQEEALPDGAELTPQTWFCGQLPLPASKLDKFKDLKGTSNVNFTFLGYTELYGKSARHFRLSVRQPVDSTTTSTTANTGGLNTTGAFSLPEVVEFDYFDNRKDFSPLGFEVNHPIAGHIMIQVVEYANLTAADISSSTFAVPATATCTNDTSIPRLSSPFTVPPFYDPTLRSTPRANRDKLIAANPTPSTGRRLAEEAAQRAAEWAALDHANGTDIAAWPRWALEVYGSGGDRVHVRERLLMESGRLRGRIMQELDCYANKYTKRWEPAALPCTVEASVIQYRHLEVIGACDGSNIAAFPFLKINGNAAINTCTKQATGCTKVTLALQSVVAAVPVANLLAAWIGLRDLEMFLCAGYNLADFEGYVTGLLGTGVSLIRGELVGTLKWSPCCVWVNEVSLEGFVGVSAGSYDLSSSIGKWMIVKEPWYWKGGAVDATRNRQPEVQNQGALEPVMVGAAEWGDWGEIGYCHERLPADSGTSNARPITGFSQRLEASGGSGKDDTGLNGLKVKCTNGDEVVVEKGSWGDWSSSISSCPAGKYITAARIKIQPNQGLFTDDTAANGVEFRCSDNTVIKSGAGDYGSWSAWAACPASQYICGLQVKTQPAQGIFGDDTAVNGLRFYCCYLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VU36</accession>
    <name>A0A835VU36_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Kinesin motor domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_014908</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000111">
        <property type="protein sequence ID" value="KAG2425908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="545269at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003777">
        <property type="term" value="F:microtubule motor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007018">
        <property type="term" value="P:microtubule-based movement"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.850.10">
        <property type="entry name" value="Kinesin motor domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027640">
        <property type="entry name" value="Kinesin-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001752">
        <property type="entry name" value="Kinesin_motor_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036961">
        <property type="entry name" value="Kinesin_motor_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968">
        <property type="entry name" value="CENTROMERE PROTEIN E"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47968:SF36">
        <property type="entry name" value="KINESIN HEAVY CHAIN ISOFORM X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00225">
        <property type="entry name" value="Kinesin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00380">
        <property type="entry name" value="KINESINHEAVY"/>
    </dbReference>
    <dbReference type="SMART" id="SM00129">
        <property type="entry name" value="KISc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50067">
        <property type="entry name" value="KINESIN_MOTOR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2 5" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="1" id="KW-0493">Microtubule</keyword>
    <keyword evidence="3 4" id="KW-0505">Motor protein</keyword>
    <keyword evidence="4" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Kinesin motor" evidence="7">
        <location>
            <begin position="663"/>
            <end position="1003"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1045"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1407"/>
            <end position="1575"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1692"/>
            <end position="1726"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1790"/>
            <end position="1827"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1852"/>
            <end position="1886"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="1946"/>
            <end position="2028"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="2177"/>
            <end position="2246"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="2367"/>
            <end position="2429"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="5">
        <location>
            <begin position="2454"/>
            <end position="2488"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1049"/>
            <end position="1074"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1095"/>
            <end position="1144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1145"/>
            <end position="1161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1170"/>
            <end position="1180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1216"/>
            <end position="1228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1258"/>
            <end position="1298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1306"/>
            <end position="1355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="1359"/>
            <end position="1370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1380"/>
            <end position="1389"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="729"/>
            <end position="736"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023054"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00283"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2425908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2676" mass="276876" checksum="42D0F27B5E599FD9" modified="2021-09-29" version="1">MAGCSSCSARAAPLGPQRRQQQHGRRQQQGCSGVAVTAACTASYDAATSASARRAVSWRLLAAPPPFGCRSLAQPPFGCCGQRSHLGVCSPRCLMAAAGGVATLRLPQPGAASFRLLRAAQPPRRLLAALPYGGCWRRRHPSVAAAWRSLLSAAAGSAATSASARRAASWRLLAASPQFGCRSLAQPPFGCCGQRSHLGVCSPRCLMAAAGGVATLRLPQPGAAPLRLLRAAQPPRRLLAALSHGGCWRRRHPSVAAAWRSLLSAAAGSAATSASARRAVSWRLLAAPPPFGCRSLAQPPFGCCGQRSHLGVCSPRCLMAAAGGVATLRLPQPGAASFRLLRAAQPPRRLLAALSHGGCWRRRHPSVAAAWRSLLSAAAGSAATSASARRAASWRLLAASPQFGCRGLAQPPFGCCGQRSHHGVCSPRCLMAAAGGVATLRLPQPGAASFRLLRAAQPPRRLLAALSHGGCWRHRHPSAAAAWRSLLSAAAGSAATSASARRAVSWRLLAAPPPFGCRSLAQPPFGCCGQRSHLGVCSPRCLMAAAGGVATLRLPQPGAASFRLLRAAQPPRRLLAALPYGGCWRHRHPSVAAAWRSLLSAAAGGAATSASARRAASWRLLAASPPFGCSSLAQPPFGCCGRRSHLGVCSPRCLMAAAGGTATLLRQLRIRPPVRSGAPPLSIKGQYGSFTFDYVIEEGTSQEETFEYAILPSVQNFLQGVSSVVLAYGANSTGKTYSLEGGPAASRREGAIPRALHAICKNLAVVPKHRYKLYVTYCALSAGVEAQLVDLLAPGSPPVSLKDGSATTALARLLHYQVESYEDVYEVLRQGRMTRAAAFTAAGGSPDLRGGRGAAGAVRGSAAPLTGPAHVMLNIQLTGFAASGEQLATNLTFVELAAPEAKDMMGYPSGTDGGVTRSLSLAYTALSGVIAALRAGGGRGGGGESPPPRHSHVPWRDSPLTRWLKGCLAGAGSILVIAHVAPGPEAAADTLATLSYVNRLRSGPKSDGLVVTATWDAAGGAAPGFEAAAAQQEVLQATLQRASQAQQAQRERMERELLLDRERHDRARERERQGQRLGEGEAEGERFGSPIQVRGSPSSMAGSSLRPQSQARYSPPTQLAPSLDTRYTTAPASVTSHRSVSVPRSGTPAASAAAVTAGPGSSRPPAGSTVAASVRSSLHSQPHAAPGPVVAASTPRSHHSQLSSPKRSSHTPEPSEPAAPLAASAAPSIQPLRTSDVLSAGGGGQSTRASSVMPPPSTSRQPSQRLAPSAPPSNASASLPPQSLASAPLAPPSHTSTHPPAPSMPPAAQSAAASQSQSRAGPLSDLLASLQLGGGSQQQRQQQDQQQQHQLQPQPFAVSESSFGPSSASRRTGAPPSDFGAAGPAPTATGAGAAAAYAAAGADAAALDALGRQVEQLRAELGAERRETQRLRAEVSSLESAHRTAADMADAQSALALAEARVQVEALRKQLDTSEGAKQVLVRRVQQLQEQQGAVLDLQAESSLLEAQVRALQDSLDGARSAHSSLAGQLADAKAAAEALRQDRDHLQRQNIELSEKLQAQVRALSDETARLRSQVLEAAGQVEAEQVARRAAEAALAQVRVQVESSRGAEGSALQQAAALAAQVKELGGALEAVRAERNKLQEAKWRSDERAEQLGLELEAALTQRAKQDMEARAAATKAESDLRSAIVAAEGLKVELGGARSQADSLKQELRAAQLAAEEAARRESALATDVQEVEGLMRELDRDLEVQVNAVWRQLRSERADSLFGRLDVGSLPPARRWRPVLTALVGIVKRNANEAERQAQALEQARERCAALEASAAAANELATSLAAHQQIKAAQLAELDESRRGVALMDQALAEANRECQRLHRQLEEATAAHKAFAAEASAREARMQAHLAEREATLQAQVSDREERLRAATAEHEKRLAAVTAEWENRLQTQLGNVEAQAEADAAEAAAKLRDLLDQRDSALSAAEAEGAARLAAAVAEREAQLQRAVAEADARLREAVAEREARLAALAGERESLARQVASLSAVQADDRQERDALRLRAHGRDQLLNILWSEVRAAKLAAMGPGGAGGSPPRTPAPGGFGFGVASSSSLSSSPAGAGLLAAAAAADADAAGPMDWGEPLCQERLLQCITTVRVQVSKLQGEVGSLRAGAGLAEELGAQLGAARGRLGEAQRGVEQLTARVGALEEQLREEQKNRSSLQQQLASGEAAAAALQSSLSEARQTIASLQEEAAVLSKSRDTWKDTATQQEAQLRELYTEGELRAGELARLRAEAQAAATDACGATARVRLLESQLQDAQSQVEALGARLSATDKALGDANARAAALNGQLVLAESEARLKAQELLARVASAEDGEKLAKANAKEAMDRLEVRLRDASEQGSKLVADLDGLRAERNEAQLRADDLQRQLLEARARLADGELTARQLAKVVAERDGLQEQVNGLRTAHLQAADEARSLRRQLDAAQDQVARLGEDKARLAAAVEGQRLEAIMAGMAGRAAGAAAAVGAAGGVGVGVGAGGGIGSSLGRISALSRPGGGGGGVAEGVGLGGGAEARGTPAPAYRAYGGLSYPAVGVGSYGASPTVARPIASYGAGYGGGAAAGLAPFSPQAPATASSAPVYGETSLRVGMGMGGYVPQSGAGAGGAGEAMAVRVHIQASPADVGGTPAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VUR1</accession>
    <name>A0A835VUR1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_014894</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000111">
        <property type="protein sequence ID" value="KAG2425891.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VUR1"/>
    <dbReference type="OrthoDB" id="528013at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.20">
        <property type="entry name" value="Vitelline membrane outer layer protein I (VOMI)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005515">
        <property type="entry name" value="VOMI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036706">
        <property type="entry name" value="VOMI_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841:SF0">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER 1 HOMOLOG A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR18841">
        <property type="entry name" value="VITELLINE MEMBRANE OUTER LAYER PROTEIN I-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03762">
        <property type="entry name" value="VOMI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51092">
        <property type="entry name" value="Vitelline membrane outer protein-I (VMO-I)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="239"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="197"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="17"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="34"/>
            <end position="54"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="182"/>
            <end position="194"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2425891.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1279" mass="135391" checksum="26C42CC3BB05B1B3" modified="2021-09-29" version="1">MTDPPPSASGPPTPRAPPAIVASTWNASGDGNMRAPAARAGPSGQPPSAAASAPVTTAGLASPRSGYTAALLPPPFSARSRQASMSHPRPVAEGAEQDEGALVPVEDVADEHTAAVGGSGRSVRIERPASRAGPVAGAAVGVAGGGVAVADIAAAKGPSLKPSMSTANKVSPAPHYEQQHVTATSTATPSSATAPPLPPNDTDKVLNEFDVNRDQRLDANELAALVSKMVQEREDKRRLVWGLGAVLVVLVVLLGALTGMTWAVVAAFKDTDVKGGVMYVKGSTSEVVQTASSEMTIVGDDLQPELGECAPGRASACALINRQALAAVNTTTATAANANGTAAVLTQQPESVVRTATFVGTPIKFSSRVNIKQLMELKYLYITGMGEVEVALVVQGVARVPDPDSVWGTVVHIITGAGTITLDDTVIRFEEGIAPVFVKAGFIVSHSRRSLLGIYDVLGFFNFISDLEVFNLPPDQPKPSLPASNFMMRLKVYEPCVFPFDPTNDRCIAPPTDGAPNPDSRRRLLQQQQLGPLAPPSPSSPVLPLLASPDAPPSAAYAGAAAAAGPAAAGERRRRTLATAPHTHARLLADGDAGAFLHDLAGVEVVNGSRYMTHTETALVWQGFMRTVYEYALFPAYRRVEVASNSSALMSVWQEEALPDGAELTPQTWFCGQLPLPASKLDKFKDLKGTSNVNFTFLGYTELYGKSARHFRLSVRQPVDSTTTSTTANTGGLNTTGAFSLPEVVEFDYFDNRKDFSPLGFEVNHPIAGHIMIQVVEYANLTAADISSSTFAVPATATCTNDTSIPRLSSPFTVPPFYDPTLRSTPRANRDKLIAANPTPSTGRRLAEEAAQRAAEWAALDHANGTDIAAWPRWALEVYGSGGDRVHVRERLLMESGRLRGRIMQELDCYANKYTKRWEPAALPCTVEASVIQYRHLEVIGACDGSNIAAFPFLKINGNAAINTCTKQATGCTKVTLALQSVVAAVPVANLLAAWIGLRDLEMFLCAGYNLADFEGYVTGLLGTGVSLIRGELVGTLKWSPCCVWVNEVSLEGFVGVSAGSYDLSSSIGKWMIVKEPWYWKGGAVDATRNRQPEVQNQGALEPVMVGAAEWGDWGEIGYCHERLPADSGTSNARPITGFSQRLEASGGSGKDDTGLNGLKVKCTNGDEVVVEKGSWGDWSSSISSCPAGKYITAARIKIQPNQGLFTDDTAANGVEFRCSDNTVIKSGAGDYGSWSAWAACPASQYICGLQVKTQPAQGIFGDDTAVNGLRFYCCYLVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VVW7</accession>
    <name>A0A835VVW7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_013451</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000074">
        <property type="protein sequence ID" value="KAG2431322.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VVW7"/>
    <dbReference type="OrthoDB" id="1875751at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006417">
        <property type="term" value="P:regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032:SF6">
        <property type="entry name" value="RNA-BINDING (RRM_RBD_RNP MOTIFS) FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48032">
        <property type="entry name" value="RNA-BINDING PROTEIN MUSASHI HOMOLOG RBP6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0677">Repeat</keyword>
    <keyword evidence="2 3" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="15"/>
            <end position="88"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="5">
        <location>
            <begin position="102"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="277"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="279"/>
            <end position="299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2431322.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="299" mass="30611" checksum="6E74EBEA86FD71A4" modified="2021-09-29" version="1">MASEEQAPSSGTPGGKLFLGGLSWDTAEEKLKEYFAKYGEVQDVVVMRDRVTRKPRGFGFITFADPAAAQAACAEPHTIDGRQIDAKPSVPHGEGGQQPRSKKIFVGGLAPETDDASLKAYFEQYGAVVEALVMVDHNSQRSRGFGFVTFAEEPSVEKVFAAGQMHELGGKQVEVKSATPKGSGPQAGRGAGRGAVSAGGAYGGRGYGGGGRGGYYQGQGYGGYGYGAFPGYGAGGFGGYGYGNYGMMGYGAGYGGMMGYGGYGGYGNYGYGNQPYGNQQGGRGGRGGGGSGSAGEGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VWX0</accession>
    <name>A0A835VWX0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ABC transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_013060</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000068">
        <property type="protein sequence ID" value="KAG2432342.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VWX0"/>
    <dbReference type="OrthoDB" id="6500128at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005743">
        <property type="term" value="C:mitochondrial inner membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042626">
        <property type="term" value="F:ATPase-coupled transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006879">
        <property type="term" value="P:intracellular iron ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1560.10">
        <property type="entry name" value="ABC transporter type 1, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036640">
        <property type="entry name" value="ABC1_TM_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003439">
        <property type="entry name" value="ABC_transporter-like_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039421">
        <property type="entry name" value="Type_1_exporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221">
        <property type="entry name" value="ATP-BINDING CASSETTE SUB-FAMILY B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24221:SF470">
        <property type="entry name" value="MITOCHONDRIAL ABC TRANSPORTER ATM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00005">
        <property type="entry name" value="ABC_tran"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="ABC transporter" evidence="6">
        <location>
            <begin position="4"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="113"/>
            <end position="139"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="120"/>
            <end position="131"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF00005"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2432342.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="234" mass="23266" checksum="B6EB2161432E4453" modified="2021-09-29" version="1">MQVGERGLKLSGGEKQRVAIARAFLRSPRLLICDEATSALDSATEAAIMESLKELAQGRSTLFVAHRLSTVRGCDRIVVLRGGRVVEEGSHDQLMERGGEYAAMWNLQADQHDDEDAGADGMGGGGGGGGSNSHVDDGGVTDTEAEIELALEAQHTQQAAAAAAAAANGSSKRPVSVAAAAGAVVGGKGGPAGLSLDSMDEVATYSRRAAAAVVAAAASATAAAAAVGGGVNAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VWX5</accession>
    <name>A0A835VWX5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">FIST C-domain domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012931</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000067">
        <property type="protein sequence ID" value="KAG2432357.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VWX5"/>
    <dbReference type="OrthoDB" id="538389at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032436">
        <property type="term" value="P:positive regulation of proteasomal ubiquitin-dependent protein catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000209">
        <property type="term" value="P:protein polyubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14939">
        <property type="entry name" value="F-BOX ONLY PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14939:SF5">
        <property type="entry name" value="F-BOX ONLY PROTEIN 22"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="494"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="786"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="272"/>
            <end position="293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="294"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="501"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="786"/>
            <end position="805"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="806"/>
            <end position="837"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2432357.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="868" mass="82854" checksum="594658DC9DA37BE0" modified="2021-09-29" version="1">MLGAMDFALLFVANYEGVKGGLAAPVLEALAAKLPPGTQVVGCATSGLMGVGPGGPFELDPSDGGGGGRRRGARPGAVSVLLGRMPGCRVRAFCNLAPVPPTPGAASRRRSSDSSRAGGPPAAVVAANAAVRQWLTSPDPRAAGLAAAVAAATAGAAGATAAQTRKGPAVAAAAAAAPAGPEDGDHAGAAAAAGPAAAAAAAATAASLGLQSVWLLMAGSNAAYNQLDGLLEWMQRDDRARPVIAGGVSSGRGDLFFHPGLPPRPPKERTASGGGGGGGSGGGGGGSAGGGGEEAAPAAAGSTGAEATGAAKRSRSRSRGRAAATAATAAATSEITAAAPVSVGFCHWDPATAKGLCYVGLAVCAGGGDAAGGSEQPAAAAWAPAAAAAASGAGAGAGRGTAHAEGEAACGAVAAVRACAYAMRGCAGLPNQPVFERVGVSREELVVRRQRPAAAAAAAGAAGAEAAAAAAPAGAAAGAEAEAGAVAAAAAEHAAAVSSSSEDEEEDSEEDSDDGDDGGELVIVSGGVAAGERGSSLHDQLRRVVAETHSLPYLALWRAERGDRSITHGLDVQAFTGGRLVLGQVEPQLLALYGVVGFRTDDRAALDAICGTPGTAGAGGAAEAGGGAGGGGGSGAGAGAGNGGGGGGVPAGSVVCCQLADITPEGCRLHLRSELPVLRSVCSAYPLLPGGRPDPRSWAGYDVARRAALAAGGRSGPVALCVFSCTGRGRAIFGEANAENEARIADEVLQRGVPFLGGYMNGELGPYVRHGYAGWFFNPLCVQPPGSSSSTTTATSSSSGSAGSRYGEGGGAGGGGGGTRGSHSGAGGGKGGGGGGSAPRCTVVAGGRVLPLDKTQMQGYTSVYAALG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VX80</accession>
    <name>A0A835VX80_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase 48 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_006658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000066">
        <property type="protein sequence ID" value="KAG2432672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="542883at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000148">
        <property type="term" value="C:1,3-beta-D-glucan synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003843">
        <property type="term" value="F:1,3-beta-D-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006075">
        <property type="term" value="P:(1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003440">
        <property type="entry name" value="Glyco_trans_48_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741:SF48">
        <property type="entry name" value="1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741">
        <property type="entry name" value="LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02364">
        <property type="entry name" value="Glucan_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1303"/>
            <end position="1324"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1331"/>
            <end position="1357"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1363"/>
            <end position="1382"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1428"/>
            <end position="1445"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1457"/>
            <end position="1481"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1530"/>
            <end position="1556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1568"/>
            <end position="1587"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1607"/>
            <end position="1626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1638"/>
            <end position="1658"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1678"/>
            <end position="1701"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase 48" evidence="3">
        <location>
            <begin position="818"/>
            <end position="995"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase 48" evidence="3">
        <location>
            <begin position="1070"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1728"/>
            <end position="1765"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1728"/>
            <end position="1742"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2432672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1765" mass="184724" checksum="C2606A75C74B213E" modified="2021-09-29" version="1">MPLLPAPPALPTSMPAAATHPTETTTAASPPPPPPSTGATPTASPAMPAGPAASPTPAPAQGMGLATAKGVSFEVWKLREATLLTTAPVWNALVRSLRQRDLLSDTEARNMSFRAVDSLSPSRMLALVPPAVAAEDGDGGELSDGMARHGSVTLPGGGAGAGGVTGRWARLSSTVTAANALNLSSGSGMAGGGGGGTFNGMMALGALGTLNGSRRHAGQLESLKAVARGENTFLPPLAVYVAQIPQMLSSWRPTAEQLDVLLEACVYWLALLVGAGAVRYPSTSSDLGHLACEREALEGAVVSRADRRTERVRREGGVGSAAAPLVETRQEAAARQRERERAARMQGGGLAQQRHELALPGGGGGGVGGGAAPADNAAAAAAAAASAASAASAAAAAAAAAAAAAAAAASAPHEWVGVVPAEVLVFELFGQSSMGGGTAASPTAQGARRALLAEVHKLVKKLKETMEVYTNTEKRVAATRKAEAEARKAAERAGAAAFLARQQAAAAPSAPAAGAAIAAEAAATDSQRALEAARAAVGAAEAEVVAARDKAVEGLGAALHCTALAATKVHDLPVSVAALAYNVVTMRHYLQDHTLEVMHRSLAAVAARSRGGGGGGGGGDQQPAAAAQEQRKGQQQRGGGQPPGQVHQQGKEAPVPFREDFIEVAEWLSGILSSSDEGTAPRNEEAVALLADFCSGLNCPNMPPPPPVAAMRSVTTLIPHYHETVIYALSSADAGRVLGPGLQGGLGGDEVLFANDSLSCPQRSQLLTYLLSEFPDEFQNLLERCASAGVRPLPEAEKGQPYDLYDFLPGGGRLYEHRAQLLLWASFRCQTLSRTVDGMSMYRIALALQAALDSLELHAARQLHHQAVAEAAAAAAGAEGGGGAVATAATVPAAGDAAAAAPSPNALVLTKEQATAVRAALRDPKHEVVEDLVEALLACLPGLGPLLDKKYGTVVASQVYASLASSRSLKDRWVAHGVALLASRYPSLRVAYLEPVESVTLIQEPDYAFKLAWYDSALFRAVPLEEAARRSGLKRAQLHRERRQLWDLRAAELETLFRLRQPLNVCGDGGGPILGEGKPENQNAAAPYCLGLLQQAIDMNQDNTLAQSLKLRNVTREFESLHSPGGARTNGGGPRALAGPLEPSAQHVAIVGYPEWIFSYRCGLLADLAAATERTFGTQIQRVMGFPSAARAHYGHPDLWNRLFSMTRGGVSKPNAGQHVSEDVFGGYNALKRGGLSKYVNYISVGKGRDMGLDSILGFEGKISKGCGEQLMSRDVRFIGAHTDFFRSASLYNTGPGHFINTWITVYTIRAGLWVMLLLLLGGVGEGSGNIAAAIGAVQILQLGTLPLLSFVFNMWIENGLAYALRTLLRQLIAGGLLFHIFRSVSSAFHLTRSTLFGGATYIATGRGFSLQRKTLTQVFINYGRSHMYLGLDVLAMSILILVAGNNGQRSMPIPVVSLWSSFLVAAALLAGPFWFTPFYFRLSLVLQDAREFLAWLGGSSARGVAASWSEWNRGELATLRNDDGKQVPLYRFWSTSTLLLPRAVTCTLSVIVAVTSAKFDTKGVPDLAWVFAGSAATWLALGAWSISKRGYVASGLKPGWRWVKGGVQVIILLAVCFVVVFTLFIEKRGLRFSSVLIVLYANQQAASLMVAVMTLWMPRVMWARRQTDTAFRQLDAGLGMFLAAVLLLVCFIGEIGLIMVDKVQALVQFNDRYYSIWAAGQEGDLGDSGGGGGGGGGGGTVQGLLRRPKGKGGGGTEADKAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VXX7</accession>
    <name>A0A835VXX7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_013067</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000069">
        <property type="protein sequence ID" value="KAG2431995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VXX7"/>
    <dbReference type="OrthoDB" id="544992at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052980">
        <property type="entry name" value="Crinkler_effector"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129:SF1">
        <property type="entry name" value="ATP-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33129">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2431995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="486" mass="53822" checksum="B8D133A671DBA9C1" modified="2021-09-29" version="1">MMRALCSQAVPAPGEVLRLEGAGFVPDVDLRGVYIRECYKGLADVMLTSPLKKFILTGTPGVGKSTIFYYFVGRLLQQRSTPPPFIIWQHAFYSGGRAFCYNTKTGDTLCGEVSSFMAALMNPDTWYIADAMPPELKTKAHLLLITSPKRDTYKVLEKRGARMLHMPPWSLEELQACRSKLDLSVSEAFVKKCFEYGGGVARYSLLQLEASNNDVEELLREGLLQQLRGAIDTSSVSQVRAALADVATQDMGLDTSHRVIHIKTDSSYSKRLLEFASRWVAERFMNKAAAEDEYGLVSLVNGSQDTFRGLMHEVWMHRTLPKGGEFTIAPVKLTGGTPKLVREAEYTLKLPPCKEEVFEEVVDLARKGCEEGVYYKPVSARLPLVDSLLRVGGVMNLFQMTVSPDKPVDFAKLEGLLGDLGITPQQEARLIFVVPEDIYPNFKINVKTGECGQKKASPTAPALATRPKLCIMRVPRAQVGVRALSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VXY8</accession>
    <name>A0A835VXY8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013938</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000082">
        <property type="protein sequence ID" value="KAG2429988.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VXY8"/>
    <dbReference type="OrthoDB" id="547935at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="84"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="104"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2429988.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="395" mass="40866" checksum="9ACE26DC9AC51521" modified="2021-09-29" version="1">MLQDSRGGAPLHIYMQGDSALRQQKNFLCHLLQPGFSGDLWALDVALRHAEPISGCYSPELGVRVTHVDNSCCNTDTLAHLARTDNDPYGSPEPPAWRPGGVGTSSSSSSGNGSSTQSHQSLPATHRDTTLVLYLNCGLHLMHLGVARPFECLPEQYGYMRLLRDFSDAAARLYPLSPQLAGNIPAITAACRNGLFIGESSRLLRERMLMAVAMLRRRHHGRAYITGSAAAAAAASAHHRPAGGGASAHGLGAAAADLVMTAARAPTGAPSAAAASGRRLMDSSAAAAATATTSVAAAGHASPYETVQNSQAVAEGGGAEAAAREWALAEGASASAASAAVPPTTVDVVDGYAITAGQCWASQVSDGRHYPYLVPMQVPFQLVCSPPAAAKVRNP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VXZ5</accession>
    <name>A0A835VXZ5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_014096</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000087">
        <property type="protein sequence ID" value="KAG2429161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="548621at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.120.10.80">
        <property type="entry name" value="Kelch-type beta propeller"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015915">
        <property type="entry name" value="Kelch-typ_b-propeller"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006626">
        <property type="entry name" value="PbH1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011050">
        <property type="entry name" value="Pectin_lyase_fold/virulence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319">
        <property type="entry name" value="G PROTEIN-COUPLED RECEPTOR-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11319:SF35">
        <property type="entry name" value="OUTER MEMBRANE PROTEIN PMPC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24681">
        <property type="entry name" value="Kelch_KLHDC2_KLHL20_DRC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00710">
        <property type="entry name" value="PbH1"/>
        <property type="match status" value="7"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF117281">
        <property type="entry name" value="Kelch motif"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51126">
        <property type="entry name" value="Pectin lyase-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="3064"/>
            <end position="3082"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="110"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="181"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="574"/>
            <end position="599"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="716"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1060"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1243"/>
            <end position="1272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1969"/>
            <end position="1993"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2082"/>
            <end position="2115"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2137"/>
            <end position="2196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="181"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="574"/>
            <end position="585"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="718"/>
            <end position="730"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="732"/>
            <end position="753"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="764"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1373"/>
            <end position="1386"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1973"/>
            <end position="1993"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2085"/>
            <end position="2100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2161"/>
            <end position="2196"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2429161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="3086" mass="311705" checksum="DF10D4A4973226BB" modified="2021-09-29" version="1">MGTTTTGGGGSGGGGQRHQLQQQQHRQRGVMRNASVGATPPSAAQQQQQLPRLLLAARGPGVFRWPHKAEEDLPHDPHFGEAVAIDGCGRRIISRCGGLLLHLPGLPPPTPASRVHHDGAGALQPPHTPPAAAAGSSTAAAAVTAAAGANNNDFDAAAGDDAKPALGVGLLGSSFAAGRGGAASSSFAAGHGSHGSPQKAPAPAEDVQQQQQSQPPPPPPQQQQQQPQVVEALVVEPLDVRELASKWLPALYLPPPPTVPPPRGCACVPTAGPGEKPTASTAGDAAAAVAADGGSGAAAGAAAAADAAAAVSATRSIAFGVTAASAYQQQGSALGVGSTIGATLLPAAAGSAAAAGAVPAAAAGGMPAAAAAAATVARLEHQYDGYLLPYPLYMYGNNNDVYDDSGLLLICGDMSDGGSSSSLGGGLVAARYNNNDRHDDYLHEDDIVAVATLLLPRLAHAGTRDRPWCEGGAAVCRGSTTAESRYEHVSLTSGNGLVYTFGGRKGAWPADIAPSSTIEEVDMRSLSLRSQAISGWQNVSGRAGHTMIEYQDAAGRRHLVIFGGVMYDATAAASSSSSSSSSDTSGGAGGGSSSVSTADPAANETLLNDVASVGLQDFAWVPHKPTGTAPRARKHASAVLWGTEVMLVFGGVLADGTTSSELWAYNITERRWLGQVTPQTSSYGDSPPALRSAALAVSGSTLLVYGGYKNTVLTVYAPSPPPPPPSPPTQVGPGGGGSSTGGNGTGGATGGAAGRRRGLAAADSPPPPPPSPSPPSPRPPSPPRPPPTVSLSQFQLSKALWAVDIRLAPWSPPAYVATWVRASVSMTTPQPDGSSAAASDGVLLAGFDASLSTSEEPHSLAVYVAGGCKSSKLETQSTWRGWYARYSNTAAYNITAAVSAFTDAVTAAAAAAKAGTAIPSLSFAVTLSRSRLFAHPDLLSGSGTSWVNADGGSVDLTTGQVSPLPGSLNPAFVRSQAWVINADGSGMATGGYRDADAGTDVVVTSRRLQLKWRSGGTWLPDGASLKHAFFESSSATSVMVSMLPLSLAEQPVTYGGAGAGAGAGASGNGSSSGSSSASGGAGGGKSKTGLIFLGKYDTTSSEQPEVSVGLVADAATYALTPLCAPDPASSCISVSASFTGPMRPPRREWYAAAPLAASYSGSAYDGSGSTSYSIATPLVLMYGGVAVTGGPPPGKRPEMNSGGGAAILRTALVGCDTRNQVPTNDWSTYSTCAWTKISSSVTLKTGGTGTTSSTSPAGGTTTTTGSTTPTLTAGRRRQLLAAAAAAAAAAEGGSGSTATATAAVASEEEASVEQMAAAAAESVLAAGAAAATTSAARLTLTDELDGSADATGFDDYGDGDAESSESRTNHETCSCASSGGASSSGAEGRLQWRRRQMAAAGATAARRVLQDGTSTATRTYYDSATVVAYQVDGSLPLAVRAKRGSPALVYDDVLNLRTGGSGHSPGPRVGASLSLLTGGDGRSVLLFGGATFNKTAAMANDNAVTTDELTLGADIHFLRYYGGGEPVQPLPASGVRDCPQDYTLAAIQPAGNGSSSSNSSSSNSSSGVISACVSAAPFVWGYDSSPLPASAPIAIPTIPDLPTALTTTFSCSSSRVVRVEVVASSSQMGASQAGVRITTWNGTVLMQTDGLSTSAGGMSALPSPPGTVTVLGTVELPPGLIQVWMTAFDGLGWTRDEDGMGPAAACCGATNKTCCPQLRLYSVGCNTYLTGFGSAEAMWDVGSANRRSPDYGVFRKVFAVAVAPTSASLPSGASASYLQYPFAQRGSYLHSFELRPAAGSPLPPPRHRHAAVFVNDSSMASNFGTMGVLLVYGGASSYTGVSNPGNRLSDTWVFCLANNTWMQLRPAGSPPPALVDAAITAVESQVFLGGGEYYNAASGTWQQDSSVYQLDLGLGAFYWRKLTGGANIYNTSSSSHSAYSMAYVKEANQVAFSTPTDLLMIPITIRSTVDTRGSGSSSSSSGNSSSSSSADSANAQLAGMTSVSTKSLSPLLSSMYDGDTALLTSVDLVNVTYNQPVAITAAILVQGRFSKPSKGSSKSTRLGARLLRELGHAEVMGLRRPLAVGDDGSNDASGNDAASSWQGERLGEQPPITVAPGGRRRLKLVYDGELDDFSLHHEEASTADSVGDGMSVGGRRLQQADPPPPPSPAPPPSPSPLPPPAPPPSPAPPSPSPPPPPLVTLKPWAAATAAAAWSAASNDQLLTTYLEGIALTVVDCNGNDNAMIVQQPGAVFQNLLFRNCAATAVVVDTGSTATTVRFANCVFLNNNGTRGGALRVAAGSNVSLADCFFLGNQAAYGGAVYVEAGAVLATMDGVLLMRNGNGPTSQAGGGLYAAPGSCVASLYGSAFDGNGNIRGLAANGTAAAGGTSTGGGVMLQQPACATDISRCAFARNAAGTGAGVSITSVDSILTLTISRCTFGSNNATSYGGGGLALQVIYGGISLTNVTFDDNVAAKRGGGVFSSNVRLLNATDCTFTRNGVRLGTGGGWCAEKEGSIRIDRAAVQANDALYGGGFSFSRDLTVNLTDSVFEDNLAVHAGALEASSCTWLQLDRCRFRNNSALSAGGVSIMQTSSGVRLNNCTFLANRLVVNSSMGVSAGETCGRHGVGGGGGACFDVSADVVISGGVWENNTATNGGAMWVAQKCNPIIDDTCGYVRLYGVTLRDNLADGGGGGAAFLYEANDLLASCDLFPNSTAASDLSTADDLFALAVPMTPLAAASDALVVAAASSSNSSSNSSSSSSGVLGNNATVVSVCGGAWAGNRAQYGALLATTAAAVTVVEPAGAFKSSYRSNDLLPVLVEVVDAFGQRITGGSTEAAATLGAVAATTQPLGVTTQSATGGLAGFVSLRVREVPGNYSFNISVSGTFHALAPEPLAVVVRRCWVGEVEKEADLCVPCAAGTFSFAPDNATCDACPEHAECAPNSTVADSGFIVLHEDGYWRSSPFSPQVLECPNSDACTYDGNASVAAVPWVNGSRQEVLLAALHQINARGPTAVSPNASAGALALWRQVQCSEGYTGNVCGGCLSGYGITGDATCSKCPNKSLNTLYFFLVSLINVFMIMITVSGNK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VY89</accession>
    <name>A0A835VY89_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014041</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000085">
        <property type="protein sequence ID" value="KAG2429461.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VY89"/>
    <dbReference type="OrthoDB" id="10253878at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="63"/>
            <end position="89"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2429461.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="89" mass="9579" checksum="009BCA45D071C795" modified="2021-09-29" version="1">MQRVGSELYVLEVRHCEGGFKDLRRSGAPDEGPAYQDADAAAQVFQAVAPVGLKQMQLRKLLLPSPPHHPPHAAALVGTMRHPSTTPSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VYZ2</accession>
    <name>A0A835VYZ2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012315</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000057">
        <property type="protein sequence ID" value="KAG2434487.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2021138at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050697">
        <property type="entry name" value="Adenylyl/Guanylyl_Cyclase_3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Guanylate cyclase" evidence="2">
        <location>
            <begin position="701"/>
            <end position="755"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="504"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="948"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1053"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1671"/>
            <end position="1717"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1907"/>
            <end position="1927"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1941"/>
            <end position="1965"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2065"/>
            <end position="2122"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2300"/>
            <end position="2378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2640"/>
            <end position="2661"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2746"/>
            <end position="2855"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2882"/>
            <end position="2972"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3065"/>
            <end position="3100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3247"/>
            <end position="3272"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3403"/>
            <end position="3423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="506"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="957"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1015"/>
            <end position="1028"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1054"/>
            <end position="1077"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1166"/>
            <end position="1186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1941"/>
            <end position="1960"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2067"/>
            <end position="2078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2079"/>
            <end position="2098"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2111"/>
            <end position="2122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2303"/>
            <end position="2313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2327"/>
            <end position="2350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2366"/>
            <end position="2378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2642"/>
            <end position="2661"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2766"/>
            <end position="2789"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2835"/>
            <end position="2855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2906"/>
            <end position="2915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="2938"/>
            <end position="2947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2953"/>
            <end position="2972"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="3407"/>
            <end position="3420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2434487.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="3516" mass="353579" checksum="460D708DE963F022" modified="2021-09-29" version="1">MLLVNNSSDAASSAPPAALILHTMGSTQELAGSGLLADLSELVSNHNTGEIQWPDISQLYRLQLSTYMGKIVSVPLDGGSGYMLSRTDVLTRMGISEPPQSWTELLDFIAYYLQSLSTAAALRNATSVAASGAAPLPPYPLCMPVGVACQHRFNLNVVWTSIAQTHGVEQGVHFNASAGMEPLVDSPAAAEAFRLLSALLEAAAPMEPDEACTHGALGFARGRCALVIAGMIPQLKYFTDPSVRATVAQSDIRVSPMPGSELVWPRSNGDVAAAAGAGGGLVPCTTRLCPYASAVTCSTPYCSRTRLINFAPAALLWTLTASINAKAPYLAQLLAFQVLSYLASPERYGPAEPVSPLVALAPVRDRFASVDGANADIYTRAGYDLGLMEVGLAVARGGSRRHPNRAWPLRMAGSKLYNSVVEDLLSDVRAGRIALGGPPVSATPYYRAAVAAAAAAAAAASTSGSSTALPLPSLLPPPPGSGSWMRSSSWAASLLAAIATYSSNSGGQGGRGGSSGDPDDSGISGDTDGGMPLAAAGLLDSIGLAAALAAARDTLAAHYIPEAYLAKYLTSLGRSDLSVASVSAAAGGSGPAAARRGGEPASQQLQVIIPVSVASVFVFLVAALVLALQLRRGCRSRRCCRLGCCEHAVGFGCCYWWCRRPCAGGGAATSAGGFLQQGPDSSSSPMNAAATYAPEPFQPAVIVVTDIESSTQLWEELPAEVMAAAMQLHHRVVRRLLLRHDGYESHTEGDSFICIFRNAHRAVTFGADLQTELVRLPWPRQLLEHPLCKPVYTLLPELYPFKRNKATRTVTPAAAPDAQSGLETMLQQAGDGGATAAVPPPPVPRPQTVVSAPHQQTAFSGGEVADGACGLSHWSRPADAAPAEPAAAAAAMALNLLSSSLCDDDIAAAVALQLANRTTVTTTATSCDNTITGMAAAVSAALVAGGGGGGGGGTAQGGAQPQPQGGRPQLPQSGSFRLMSRRGSYGPASAAHYQQQPGRHALLQPQPVNPEDGSSHGAAGAADGSSAENHAVAAAEAMAGVQSLLLAPNTMLTRQRTQPASAPPASQQHAAAVASRATPVNVRAVATVIGYEESQQSLMLEGSSPDDGSAAYAWYMGTAPGAHLAAARAATTGTESYGRLSARWPLRGAAHEAAAGDAAAAAACRDTAGDAAVQQQQPQPLPQRSSPARRQHPASRLLARLFNRDRAAATSATAAPAAVDAAKVATAGSGRNLLTRGIAGAVAAAATTGAGGTSAASALARRNPTHLQLCRCSTTSSLGGGHGSNSPYVTSPRRWALTPASPPAGGATDDDMFEVSLALAPVAEAVAPSADGMSHELAAASAAAGGAGAGAWGGAGASGPSPTGRALAVAPAAVAAGRPVSPHAAWLIPAGEADVMGSEDEDDEVTYTMAFLAGANGRLPSLCAAPGLPSLPSSRRCSSGAFGPAATLMALPPLPRPASWQQEGYAMPAAISTAQVPQRIAQYFAARKEVDLHHQKQLGLDTLSPSPAAAAARPAAKRATTLVYRGLRVRVGMWALPSLSPSELRHNAAAARLVVGGPCLAAAKALADMAHGGQVLVAGAAEGELQQELRYLKLKSANGGGGISLLQLGVYDDLSQHQAVAAAAQSAARQPLDEAALADLLSLDVELELAHLQLQRLRLPSMQDGYSRLEDAVTPSAATPVRAQLTPRSRTQPRLPRQALSPPGPPPSATPSAVAAATAAVPPPRGATHVLCLVPAALSARVVHTPPLRVPATLGRVSELHDAPTGAVAYLVVQVPRVAALMAWDVEAAGESLRLFRDTARRLLSAAPVRGYQVPALEDQLHVAFPAVAALAALGFAEALRLALLDAPWPQALLDHELGERIEIPARDTAAAVPQSLLAIPSSAAAVAAAAAPAVSLADAALQLHRPGEGMTSQRPPPALTPSGGASAAMPRLAVGRTPTALAAAAPGGDSDSAGGAEAAGDLRRGSTSSGWNLLRFFPTSAGGAAAGGDVAEAGRGKGPGLGAAVSVPATPAAAVHRLISAASSALTTPRKAVRWNFASQRGRGISTSPTHAGVSRTAAGILQHTPAASSQQHSGSRQPQRARAPQHQEQQEQQQQQLASAPPLTALRLPIDKDDRPPPEREGAALLAAEAGASQRPESWTDTSVLLGSSSVPGTQRQPHLHSTGLLLAAARNSSRGGGGVDLLGSGAEGVSSGGLSWQQQMQQFAAATDAISGSSVPLAGPFSDKINDKGSAAGCTRVSGLDTLRFAEYYSHCIGSAAGLEPLGQQAAAAEPAAVAAALLTPQLSAAAAAGGLRHSGYPAGTSSDSDSAIPQLQVDGQRGGGWASGAAGTAAVTGGCPSATPSSATTPVSQLGGGSGEARKRWQSQQSQPMSLRAQQRPQLIPMRGLRIRMGVATGPAEWRISRSAQALVYTGATVAAAIKLASVASAGQLLCDRATHMQATASTSGAAPAAAAAHSSDAAAPYGLAPAVAAALRDPQPAVAFSPLVARSKAKAMVGAQLCSFTQRSRAVPIPAAFPGQPTPAVTAVFGAAGLRSAPSGTTDVLRASTLLPLLRPSQPSLHNQQAPLIASYTSYKAPPGPGAASAFAPAAALALAHAASPAGRVQQPGSYEPGHGAATLRRGGSSCLASAPANAFVMRDGSSYSHGGSGQQQQASGQPAQLQQELPCTYSQLPTCCALGADTEPGLRAVIAAVAAAAAGSFGDGGSGGAQHAAGCAGPINMAVPPATSRPRSSHAALLTTSPSNMQAFRAPPPPAAVAPETGVQQHYQQQQQQQQQQQQQQQQQQQQRIRAASATPLPSPHAQRPPSRLRLLTTACGGAHPSATGAGNSRAQNASGSHHTASSAASNTGSNTATGMATTTLLLTSATSQSYSRMPLTETTAAGTYTSGGGGSTQGSSGAPPQRLLSSYPQSRASLDMAARPKSPGEVEEAPALSPDEPPPPPPPFAVVGRAASGGTASSSSAGQASSACAPPNLASSSAGLFLFANGTNGGASTTTASNYWGGGLSVTNARLASLPELPERGASGHQHEEDSCVASFIVDATVGADGPAVVAAAPAATVNAGVGRERAPNRSGLPPPLGSSPPAAVRPSHGGGAPSTVELPLLLASPTQAASATGSHDAGLQLIASSKVPLRSSASGPHEHAGTGAAAAAAALPIARTAAAALLSAEALLPTGGSSASAAPSVMLTAGSSQGGAPAPAAGAARAAAHVQAYPGSSAGVSNVRLRRLSSVRYQGGFDMVISSANSTASGTGGMRRGRGTATSASDDFAPDVGRIRTPGGAVDTHDRHSCVANTAGSDACGAASPAVAAAAASLRVPSFLAGSLLRSPMMPLLRVSCASPPERRNSSSRAAVSFARASMPTEVEASAAAAAAAAAAVRVAPAAAPGGLVGSRDTDGCYAAATAAEDPQQREGHQQEEGHHGGLLWSPFDASATPCSSSLPLPAAADLTTAASAQPALAARTKESSLAVWAAGRSAGAGGGMFPRSAGAEPGSLLLLPLRACSQSERPLQHPAYRQS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W1H8</accession>
    <name>A0A835W1H8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase 48 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_006658</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000066">
        <property type="protein sequence ID" value="KAG2432671.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="542883at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000148">
        <property type="term" value="C:1,3-beta-D-glucan synthase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003843">
        <property type="term" value="F:1,3-beta-D-glucan synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006075">
        <property type="term" value="P:(1-&gt;3)-beta-D-glucan biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003440">
        <property type="entry name" value="Glyco_trans_48_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741:SF48">
        <property type="entry name" value="1,3-BETA-GLUCAN SYNTHASE COMPONENT FKS1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12741">
        <property type="entry name" value="LYST-INTERACTING PROTEIN LIP5 DOPAMINE RESPONSIVE PROTEIN DRG-1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02364">
        <property type="entry name" value="Glucan_synthase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1294"/>
            <end position="1315"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1322"/>
            <end position="1348"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1354"/>
            <end position="1373"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1419"/>
            <end position="1436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1448"/>
            <end position="1472"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1521"/>
            <end position="1547"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1559"/>
            <end position="1578"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1598"/>
            <end position="1617"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1629"/>
            <end position="1649"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1669"/>
            <end position="1692"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase 48" evidence="3">
        <location>
            <begin position="681"/>
            <end position="986"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase 48" evidence="3">
        <location>
            <begin position="1061"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="307"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="608"/>
            <end position="652"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1719"/>
            <end position="1756"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="11"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="37"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="307"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="328"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="360"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="610"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1719"/>
            <end position="1733"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF02364"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2432671.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1756" mass="183750" checksum="3BD3BA55BFC0EF62" modified="2021-09-29" version="1">MPLLPAPPALPTSMPAAATHPTETTTAASPPPPPPSTGATPTASPAMPAGPAASPTPAPAQGMGLATAKGVSFEVWKLREATLLTTAPVWNALVRSLRQRDLLSDTEARNMSFRAVDSLSPSRMLALVPPAVAAEDGDGGELSDGMARHGSVTLPGGGAGAGGVTGRWARLSSTVTAANALNLSSGSGMAGGGGGGTFNGMMALGALGTLNGSRRHAGQLESLKAVARGENTFLPPLAVYVAQIPQMLSSWRPTAEQLDVLLEACVYWLALLVGAGAVRYPSTSSDLGHLACEREALEGAVVSRADRRTERVRREGGVGSAAAPLVETRQEAAARQRERERAARMQGGGLAQQRHELALPGGGGGGVGGGAAPADNAAAAAAAAASAASAASAAAAAAAAAAAAAAAAASAPHEWVGVVPAEVLVFELFGQSSMGGGTAASPTAQGARRALLAEVHKLVKKLKETMEVYTNTEKRVAATRKAEAEARKAAERAGAAAFLARQQAAAAPSAPAAGAAIAAEAAATDSQRALEAARAAVGAAEAEVVAARDKAVEGLGAALHCTALAATKVHDLPVSVAALAYNVVTMRHYLQDHTLEVMHRSLAAVAARSRGGGGGGGGGDQQPAAAAQEQRKGQQQRGGGQPPGQVHQQGKEAPVPFREDFIEVAEWLSGILSSSDEGTAPRNEEAVALLADFCSGLNCPNMPPPPPVAAMRSVTTLIPHYHETVIYALSSADAGRVLGPGLQGGLGGDEVLFANQLLTYLLSEFPDEFQNLLERCASAGVRPLPEAEKGQPYDLYDFLPGGGRLYEHRAQLLLWASFRCQTLSRTVDGMSMYRIALALQAALDSLELHAARQLHHQAVAEAAAAAAGAEGGGGAVATAATVPAAGDAAAAAPSPNALVLTKEQATAVRAALRDPKHEVVEDLVEALLACLPGLGPLLDKKYGTVVASQVYASLASSRSLKDRWVAHGVALLASRYPSLRVAYLEPVESVTLIQEPDYAFKLAWYDSALFRAVPLEEAARRSGLKRAQLHRERRQLWDLRAAELETLFRLRQPLNVCGDGGGPILGEGKPENQNAAAPYCLGLLQQAIDMNQDNTLAQSLKLRNVTREFESLHSPGGARTNGGGPRALAGPLEPSAQHVAIVGYPEWIFSYRCGLLADLAAATERTFGTQIQRVMGFPSAARAHYGHPDLWNRLFSMTRGGVSKPNAGQHVSEDVFGGYNALKRGGLSKYVNYISVGKGRDMGLDSILGFEGKISKGCGEQLMSRDVRFIGAHTDFFRSASLYNTGPGHFINTWITVYTIRAGLWVMLLLLLGGVGEGSGNIAAAIGAVQILQLGTLPLLSFVFNMWIENGLAYALRTLLRQLIAGGLLFHIFRSVSSAFHLTRSTLFGGATYIATGRGFSLQRKTLTQVFINYGRSHMYLGLDVLAMSILILVAGNNGQRSMPIPVVSLWSSFLVAAALLAGPFWFTPFYFRLSLVLQDAREFLAWLGGSSARGVAASWSEWNRGELATLRNDDGKQVPLYRFWSTSTLLLPRAVTCTLSVIVAVTSAKFDTKGVPDLAWVFAGSAATWLALGAWSISKRGYVASGLKPGWRWVKGGVQVIILLAVCFVVVFTLFIEKRGLRFSSVLIVLYANQQAASLMVAVMTLWMPRVMWARRQTDTAFRQLDAGLGMFLAAVLLLVCFIGEIGLIMVDKVQALVQFNDRYYSIWAAGQEGDLGDSGGGGGGGGGGGTVQGLLRRPKGKGGGGTEADKAKKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W4M5</accession>
    <name>A0A835W4M5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pyruvate phosphate dikinase AMP/ATP-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_010312</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440427.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W4M5"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050242">
        <property type="term" value="F:pyruvate, phosphate dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.80.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010121">
        <property type="entry name" value="Pyruvate_phosphate_dikinase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE DIKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931:SF9">
        <property type="entry name" value="PYRUVATE, PHOSPHATE DIKINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="2">
        <location>
            <begin position="23"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="2">
        <location>
            <begin position="67"/>
            <end position="137"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2440427.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="216" mass="23688" checksum="45224AD1CAFC23E3" modified="2021-09-29" version="1">MAPIRRIYGFARGNSDGNKSMKELLGGKGANLCEMARCGLNVPPGFTITTEVCEEFYANGGKLPEALKVEVKAAVAAVEAEMGLKFGDVNTPLLVSVRSGAAVSMPGMMDTVLNLGLNDAIVEGFAAKYGARFAMDCYRRLMQMFGDVVLEIPHEAFETKLTALKARKGVQYDVQLDADDLRELVTAYKQVYKDHKQELPQDPWQQLFLGINAVFK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W523</accession>
    <name>A0A835W523_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_011248</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000046">
        <property type="protein sequence ID" value="KAG2437608.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552574at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005777">
        <property type="term" value="C:peroxisome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039889">
        <property type="entry name" value="CCD33"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21623:SF2">
        <property type="entry name" value="COILED-COIL DOMAIN-CONTAINING PROTEIN 33"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21623">
        <property type="entry name" value="SPERIOLIN-BINDING FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00239">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="3">
        <location>
            <begin position="182"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="345"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="605"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="908"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1148"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="699"/>
            <end position="726"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1023"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="356"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="619"/>
            <end position="629"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="917"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="949"/>
            <end position="964"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="983"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1164"/>
            <end position="1173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1253"/>
            <end position="1270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1278"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1300"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1343"/>
            <end position="1371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2437608.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1371" mass="141491" checksum="221599E7755DA09B" modified="2021-09-29" version="1">MLARTETSELSRSPEFALSSFVLRLPQPLAGSPADQPLLQVQLFAAPSIDGPGSTAASSTMDELVGSGVVQCRPDMAARLLRGERVTTPVVLTDAVMGLAGGAGAESGLSSLAAGLASLGVGMGGGGRGREVLLELLLLDAHLVLPRDAFALKASYAGAPAAAAADRRASGAGGSAGGSECVLRILVSRAENLPLVMGEGGVEVEPDTFVAAKRLRDGREGGGAQALTRTVAGTRRPVWNQALELRYSEAELAAGEQLLLALVNNSNSRLMIKAALPLAPLVPDHTYNLRLLLPGGPLGSAVHLYVSLVLTGAAAAGRRHLRAHMAAAQQLLQARLADSSATALGELVPPGRGAEGAEEPELGSEPPGGDDGEVFGVWRVVGSPEQAAEPPALPDPDPYTSLDTSSEAAVRAALQKMADSHAAAVQAATLGGGSALEVTPLRAAGGQDPQPLLWPHDHMVSMLAGAASSVAPSGSSSGASGAQVLQLALYHLPPPTEHPGPAPGPRASLTKEERLLGSGPVGNGEAAGAQGGRRQARLLGLAATPLQPRPAAGLGPGQVQLVKDVPVQAVPSSSSSPPSPKPAAEVRLDLELRRRDTAAVVASLEQQAAEGNGDAASPGGNGGGGGSGLGSADMASSMTWQGQAGALAAAAAGGAGGGPNGPVVEALVEDCVVKQGAVGRLIRQLDAAASTAEVASWRVADAESRVRAANDDNAKLRQLLHEEKEAWRIPQLLPDAASLSRDELVERCESAMAAYGRERRRNAELVHRLQQLHAEQVDTLELKKRYQQLQDAHMEQARNYGDLEGVDGRSAALRATIKTQEEVIRNLEALLAAAVDKAKAAAQQAAELKGAAATAEALREDMGKAAHLLQEQEKALQQSRAEAAHADQEAQQLRTQLAALAGEDQARAAGLEQQATEARERVAQLESELERARQQAAEAEQRVAEAEQRTAAAEQRVAEAEQLASKLRAELEEAQKNPPPPAEVEQPAPEVGAAPAGEGEGEAAGGEGKGEGEAGATVPSAELEAAQARIAELDAELEAAKARIAELEAELEAGKARVKELEEAPGGPEEVSRLEGEVVALTEEKTAGLLRAEYAEGAAEAAQAELIDVTKKFAREIAELKTRLAEKDAALMGGFGDLDQLRRGELPHLDMMGTGGLGAHGGPPQTPPPPPGMIMPNHQQARRPSGSPSTGARPPLQRVRSDGGSRGGTPPTGERAGSAGTGHPDARVGSPGLFPPIKGGTAQPDSHASKSAPPAPSQKAPPPAPPPPARLPAGRRVPSPQQQQQQHALQKPGQPAPPMPEDDEDDDEDGDEEDEDDDEEDDEEEDDDDDDDNEDDDEPMPPARGRGQAPQPAAARPAVPQRLPAATQRRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W5P9</accession>
    <name>A0A835W5P9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cleavage/polyadenylation specificity factor A subunit C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_011566</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000049">
        <property type="protein sequence ID" value="KAG2436631.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6109at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058543">
        <property type="entry name" value="Beta-prop_RSE1/DDB1/CPSF1_2nd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050358">
        <property type="entry name" value="RSE1/DDB1/CFT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004871">
        <property type="entry name" value="RSE1/DDB1/CPSF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10644">
        <property type="entry name" value="DNA REPAIR/RNA PROCESSING CPSF FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23726">
        <property type="entry name" value="Beta-prop_RSE1_2nd"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03178">
        <property type="entry name" value="CPSF_A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="RSE1/DDB1/CPSF1 second beta-propeller" evidence="3">
        <location>
            <begin position="915"/>
            <end position="1443"/>
        </location>
    </feature>
    <feature type="domain" description="RSE1/DDB1/CPSF1 C-terminal" evidence="2">
        <location>
            <begin position="1523"/>
            <end position="1876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="194"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="597"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="756"/>
            <end position="821"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="846"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1298"/>
            <end position="1352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="98"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="614"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="767"/>
            <end position="788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="796"/>
            <end position="807"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="851"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="880"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="906"/>
            <end position="915"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1090"/>
            <end position="1110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1135"/>
            <end position="1150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1298"/>
            <end position="1323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF03178"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF23726"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2436631.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1912" mass="190277" checksum="116C1F457B46BCB9" modified="2021-09-29" version="1">MSTCIYKECHPPTGVTQSEAAYLTHAPLPPGTAAAAAAAAAAAAEHGPAAGPRGSGAAAAAGAAAAAASAPVQHPNLVVVRINRLEIYRVRWTPGPGASSGGGGSSSSGDGATAGQGGGPGAGAGGAGGGGGGGGTARLELVYGCHLHGAVESMAVLSGGSPRRRDALLLTFRDAKLSVLEWDVRHHTLRTTSMHFFQGGPPPPPPGPLSGAGGFPPPPPPLHPSQGGGGGTHQGPAMAQQAQGQGQAQQREARTAVPLPPRVVADPAGRCAAVTMYFCQLALVPAIEGEALEALGGCAGGAGGAAAVGNSYVLNLHRMMGVREVRHATFLHGYTEPVLLLLHEPDPTWAGRLRERKDTCCLTAISISLRLKRHTVLWRAAGLPYDAYRLLPLPQRPAALVLSPNLVMLTSQASQPQAAALNSNALPGEVPPPLVFDPAREAPSVTAARVAAEYALNVHPDCAPALGRSAALVSDLEAVAAGACAAWLTPTTCLLGLQSGSLLALHLRLEPHVPPEQRITAVRTGGGPVATAMVGLSMAAAARAPAAVAAAALGAAAAAATGNLPYDLYRGPKGLIFLGSWTGDSVLMQLKPRAEGAAAVEERPAAKRQKRAGAGAGAGGEAGGGGGGGGEDGGAALTNRSAAVEAAAAAGAKAAAAEGGGGPQRYNLRLLDSLPSLGPVRDLLHVDTSVSPYTAGGGGAGGGGGPLGASRGGPTSFLCVGQGQTGALVLARQGLVPDVVTEVGLAGIAGVFAVRHRNPDDDDDDGIGGGGGIGGGGGVEEDGGGGAAGEAAVVVGEEEGEEEEGEGQEGGGKRRYGSGEPAAAATAAAAAAAGVKPEATDDATAIKTEPADGGDAAAAAATAAGGAGVKRGRSPEPPTDGAIVPVPDPAAAKPPGSSSGNGVGGSSSSSSSSGPPYHSFLLITMGTSRTMVLKCAEGLDDVTTSPECEYLTDQPTIAAGNLFHNAVIVQACPGGVRLLEGMSLVQDLPISELQALGGVAAASRPGVAPPTITHMQVADPYVLLTLSNGTALLLEADLLSMTLALVTGAAAEQLLAAPARSASHRIAAACLQQDETGWMATGAGLGAAAAGAGPGAEMEAEAEAPAPAGGAAEGEEGAVKKEAAAAADEEAAAAGDGGGSGGAGGGGGGSSSGSKFLWICRRSGRLECYSLPSMRLVFSSSSGLAGREEVLLPGPAAMMSMADLFGAATAEEDEPAGAAAAAAAAATAGGAGGGAGRGAGGSSMEDPVVEMRVDAFRGASSGGVPDCQRPVLLALTASGNLVAYQAYNPHGFHLGSSSSTSAGAGVGGSSTSTSSSSGSGLALRRLPLDTLSHEAPAPLGPPGAPAAAGGGGAGAGPVALGPRLIRFDHIAYTDPLTRARGPSHSGVFVAGGRPLWLVAGRGGLAAHAMWSEGPVAALTPFHNVNCPLGFITACSARGQLKVCCLPPQTRLDGAWVTRRVSLKVTPHRLAWFREGGILAAITSRAAPCRPRPAEEPGGDPAAAAAYAAAGAAAAGRGKEEAWELRLLEPNAGGRLWVSQLLPPGEQALCLRFVYLRNAATGETDTLLAVGTGTPLGEDYPCLGRLLLYSVAAEAVDLGRGNMSRRWSATLVASRDTASAVTSVQEFKSQLLVTCGSRVEMYEWKAAAGSGSGGSSGSSGGSLDKRAFFDLPSLATGLVTVKDYLLASDVHQGLYFLRYSDASRVIEFMSKDFDGRDVLTCGVVIAEPKLHFLAADAAGTLQMMEFYGKRDTNPEFWAGQRLAPMGLLHVARRVGVAASVALASRDGRNRHALLCGSAEGGLAFVAPVPDAGAAARLAALQAHLSSALPHVAGLNPRSFRHRFIRIPKALGGGEYHRSPLPPRNNSGLLDGQLLFGFPHLSRQAQAAAAEAVGTSPQQLMDDLRAIATAATFG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W5R2</accession>
    <name>A0A835W5R2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">pyruvate, phosphate dikinase</fullName>
            <ecNumber evidence="3">2.7.9.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HYH02_010312</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>pyruvate + phosphate + ATP = phosphoenolpyruvate + AMP + diphosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:10756"/>
            <dbReference type="ChEBI" id="CHEBI:15361"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:33019"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58702"/>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
            <dbReference type="EC" id="2.7.9.1"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PEP-utilizing enzyme family.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.9.1" evidence="3"/>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440425.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W5R2"/>
    <dbReference type="OrthoDB" id="6123450at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016301">
        <property type="term" value="F:kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050242">
        <property type="term" value="F:pyruvate, phosphate dikinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1490.20">
        <property type="entry name" value="ATP-grasp fold, A domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.60">
        <property type="entry name" value="Phosphoenolpyruvate-binding domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.30.10">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.189.10">
        <property type="entry name" value="Pyruvate Phosphate Dikinase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013815">
        <property type="entry name" value="ATP_grasp_subdomain_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008279">
        <property type="entry name" value="PEP-util_enz_mobile_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018274">
        <property type="entry name" value="PEP_util_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000121">
        <property type="entry name" value="PEP_util_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023151">
        <property type="entry name" value="PEP_util_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036637">
        <property type="entry name" value="Phosphohistidine_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002192">
        <property type="entry name" value="PPDK_AMP/ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010121">
        <property type="entry name" value="Pyruvate_phosphate_dikinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015813">
        <property type="entry name" value="Pyrv/PenolPyrv_kinase-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040442">
        <property type="entry name" value="Pyrv_kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01828">
        <property type="entry name" value="pyru_phos_dikin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931">
        <property type="entry name" value="PHOSPHOENOLPYRUVATE DIKINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22931:SF9">
        <property type="entry name" value="PYRUVATE, PHOSPHATE DIKINASE 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00391">
        <property type="entry name" value="PEP-utilizers"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02896">
        <property type="entry name" value="PEP-utilizers_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01326">
        <property type="entry name" value="PPDK_N"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51621">
        <property type="entry name" value="Phosphoenolpyruvate/pyruvate domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52009">
        <property type="entry name" value="Phosphohistidine domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00742">
        <property type="entry name" value="PEP_ENZYMES_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00370">
        <property type="entry name" value="PEP_ENZYMES_PHOS_SITE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0418">Kinase</keyword>
    <keyword evidence="9" id="KW-0460">Magnesium</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="12">
        <location>
            <begin position="10"/>
            <end position="91"/>
        </location>
    </feature>
    <feature type="domain" description="Pyruvate phosphate dikinase AMP/ATP-binding" evidence="12">
        <location>
            <begin position="103"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilising enzyme mobile" evidence="11">
        <location>
            <begin position="221"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="domain" description="PEP-utilising enzyme C-terminal" evidence="13">
        <location>
            <begin position="323"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011994"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00391"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF01326"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="Pfam" id="PF02896"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG2440425.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="688" mass="74924" checksum="FA2DC2F8100B54A6" modified="2021-09-29" version="1">MVPAVLGASVLWSWNIPRAVKYREINKITGLKGTAVNVQTMVYGNMGETSGTGVCFTRNPANGTAELFGEFLINAQGEDVVAGIRTPMPIKLMADVMPPIYAELVANTTMLEKHMKDMQDVEFTVQEGRLFMLQCRNGKRTGTAALRIALELEAEGLITKDEAVLMVEPRHLDQLLHPQFQDEKKYAKDVITRGLAASPGAAVGRLVFSADEAEEWKARGERVILCRHETSPEDVGGMHVAEGILTCRGGMTSHAAVVARGWGKPCVCGCEQLHIDLKSKTLTFELHGKEVQLHEGDWVSLNGTTGEVINGAQPLKKPEVTGGDLGKFMAWVDKARRLRVLTNVDTPEDAAIARTNGAQGIGLCRTEHMFFSTHERIAAMRRMIAEEELESSHKMEALETLKAFQRDDFEGIFKAMDGLPVTIRLLDPPLHEFLPQEGPAMEALCKQLAAELNASVERVEARLNGLREVNPMMGLRGCRLGIVHPEITDMQAVAIFEAATKVMAAGGKVHPHIMVPLVATIDEMDHQLNVIHAAAKRVADASGKKVPYKVGTMIEVPRAALQAGHLAERAEFFSFGTNDLTQMTFGISRDDAQAKFLTTYTRNGILQTDPFDTLDIVGVGEMVKIAVERGRATKPNLELGICGEHGGDPTSIAFFNKVGLDYVSCSPLRVPIARLAAAQAAIKAGKAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W6R4</accession>
    <name>A0A835W6R4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_011046</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000045">
        <property type="protein sequence ID" value="KAG2437666.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W6R4"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17487">
        <property type="entry name" value="MFS_MFSD5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="6"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="45"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="134"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="175"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="206"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="268"/>
            <end position="285"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="291"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="381"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="413"/>
            <end position="433"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="439"/>
            <end position="457"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2437666.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="485" mass="52575" checksum="F17DAA0A973443B8" modified="2021-09-29" version="1">MEQVYWVIFGVLAFIVAGLVLTQAKEGGLVSGAGSQLQAFFALRNNYVFVYALMMAGDWLQGPYVYALYQHYGYDVKDIGRLFIAGFGSSMIFGTVVGSLADKHGRKKAALLYVITYAASCATKHSPDYGILMVGRLLGGIATSLLFSAFESWLVAEHFSRGFDEKWLGDTFSKAVFVGNGLMAILAGLVASYLVDSLKLGPVAPFDAAIVVLLAGGAVIYASWPENYGDHAHAAEGVLDVLRRQFAVAAGAIIGDQRIALLGAMQSLFEASMYTFVFLWTPALAPAGERIYHGMIFACFMTASMAGSSLSGILMKRYKVESYMKYVFGLSAVALAVPFLFHVSIADQPSSDSHRRSLQEATLAAGKEVVRGISLQGQMQLVAFCLFEVLVGVFWPSMMTLRARFIPEETRSTIINVFRIPLNFFVCVVLYNVHLFPLSSMFALCATFLAIACVLQVRLERLIQVRPEPAAGVPPAALGAEPGKV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W740</accession>
    <name>A0A835W740_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_010448</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000039">
        <property type="protein sequence ID" value="KAG2439813.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W740"/>
    <dbReference type="OrthoDB" id="531307at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2439813.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="151" mass="15019" checksum="3944BE73937CD0A7" modified="2021-09-29" version="1">MVGSSGHKKAPAAARPAVSLAAALLVLLVLLVPAGPLLLQRGGQLLASAQQTDRQVNSDGGLYAALTNPAITSIGIAYSGASLAPYAQALYDAVAASGPFQLNRSLTLYGAAAGASLDFAYVAGVVKAAPGTTLTLKGACVLLQACCCYSL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W7V7</accession>
    <name>A0A835W7V7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Anaphase-promoting complex subunit 1 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_010679</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the APC1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000042">
        <property type="protein sequence ID" value="KAG2438881.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="26401at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005680">
        <property type="term" value="C:anaphase-promoting complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060090">
        <property type="term" value="F:molecular adaptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031145">
        <property type="term" value="P:anaphase-promoting complex-dependent catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051301">
        <property type="term" value="P:cell division"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007091">
        <property type="term" value="P:metaphase/anaphase transition of mitotic cell cycle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070979">
        <property type="term" value="P:protein K11-linked ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024990">
        <property type="entry name" value="Apc1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041221">
        <property type="entry name" value="APC1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827:SF3">
        <property type="entry name" value="ANAPHASE-PROMOTING COMPLEX SUBUNIT 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12827">
        <property type="entry name" value="MEIOTIC CHECKPOINT REGULATOR TSG24 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18122">
        <property type="entry name" value="APC1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0131">Cell cycle</keyword>
    <keyword evidence="2" id="KW-0132">Cell division</keyword>
    <keyword evidence="3" id="KW-0498">Mitosis</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Anaphase-promoting complex subunit 1 C-terminal" evidence="6">
        <location>
            <begin position="1367"/>
            <end position="1516"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="750"/>
            <end position="780"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="787"/>
            <end position="806"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="846"/>
            <end position="902"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1266"/>
            <end position="1326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="755"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="863"/>
            <end position="876"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="877"/>
            <end position="890"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1269"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1297"/>
            <end position="1316"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010547"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022618"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022776"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023306"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF18122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2438881.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1846" mass="176471" checksum="D081103033DA7EEF" modified="2021-09-29" version="1">MRSCAAASGTVAPGAGVGPGPGAAPGWAAAGVGAACMVAAAGAVGAGAVPGAGGPAVATKPDVPSYTHAGLLMALGLTGQLDRLSWTDLYRYLSDEHDPTTIAVLVGMAAQRRGSMDATVTRMLFLHLPARHPTSFPELELSPLVQAAALMGVGLLYEGSAHRVMAETLVEEIGRRPLSPAAAAAFAAGGAGGAGAGGAGGAGAGGLLGGGGGAGGAGALPPGASPLAVTHDREGYALAAGFALGMVTLGLGGSRAAAGLADLQLEERLTYYMLGSTDASAAARRAGGMWGGGGGAGGGGGGGGFDRVFGHNGTGAGAKLGHAPGLWGGDGAGPAALSAPAGARSGEGGANGGANGQGVALVVLEPDNALNLSITSPAATVALALMYLRTHNAAIAARFALPDTPYGLDATRPDVVTLRALGGALVMWDDVRPCEGWLQASMPPLFRGPLDKLIDKVVQHLHAAPAAATAAAAAAAAGGAGGAASRRAGRTASSAPGDVHAVALAHVSALSGLCLAIGLKYAGSANAAAYETLRGAALALLAAKRRVPEVVPSSTAGGGAAVATGAGQVAGGGPAAVGRLDRAPLEGALSVVVLALSLVMAGTGHLPTFHLLQSLTARRHPSQHHVLSSLGVGYGAHCAVSLALGFLFLGAGTHTFSTTNSSVAALLVALFPVLPHTPTDNRCHLQVFRHLYVLAARRRCLEAVDVDSQQLVYVPLQVALQPPPPPPAAAPSSSAAAAAAAAAAAGKHGAAAAGDGAGPRRGGGAGGGGGGGDPMQTEEGGVLRTSTKANLPWTPDGQLRPGLGPGLTPVSASTTTAITPGPPGLATAAATTAAAAAAATSPPPMLEALHLEGDSPGRLPPPHSHHHHHHHHHHSALLRGAAAAATTTTSGAGGGGAGGSAKTPASVNLVAALPGAADGTTASSPPLPFATAAAAAHAAAAAATTAMHDAPMQLPDAQQDARQAAAATAAAAANAAAKGGEDSQLLSLLHYERVAPALLPEPHQAVRLAVRGPRYWPQQLDWSSRGAAGVDGTGAGLPSAAAAAATAAAAAAQPQPAAVAAPPPPTPYGLFPFHTPLPGGGGGGGGGIGAAAGAAAGSGAGLGGGVTGATLPPHTPSASAPSSYSYLPGTGTGAGAGAGSCPSALETVYRQLLLFVKKRAGSLSYSQDPSGIRSLLSRAFHNQGLLRQGLPLDAGSLPLPLPSVAVGAAGGAGGGGGGGGGGGGRDSAAASPAAAAAAAAAGRSAGGAAAVSPGSAGRAARRQLDWRASGGGGGGGGGGSFGGGRDVDAASPSGGARRMDLDGGGRQVSPDRRRPSGDGGAAAAAGAGGASSAAGAGAAAAADASVAAAGGGGGGGGDGGGFDLVHLCATFSVDPSIMAFAQHIKAMRDLWIATEAEAEEEAAAAAAAAAADGAGAGGNSSGGSGLRRRLSLLAAPAAAMRADDVGRSASAAAAPQQQELQLLQRRRRRWQAARRRRRHGAELLSFCYSALYECITGEKTPALPMYLHLHCLVHRAAVAAAATADINAGASGFAAGANDSGGWAVVFGQGGGGHSHGGGGGGGRLAAFAAAAAAAPLHPGSLLTAAAVPLAAPLRGLQLARAYYGGPLAAAAAAAVAASCASAGAELFSDPDEQALWRPLLQPAFLDSLWCALQHRRWRPLRLLPAPAPAAAAPTPCAGVVGSSGAGGGGGGGGGGGGALGAYLRKGRMLSASDFEVVAPGVSRLAAEPELQAELGRCLALHGLPPLADVAAALDTLRQLPAWQQVKQLAAAAAAASGAAAAAGAGAGVGGRGGVGGGAGAAVGAGALVAGVGSVAPTWAVLPLLSLVLPGLSQEALLLLAAAVPL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W857</accession>
    <name>A0A835W857_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Peptidyl-prolyl cis-trans isomerase</fullName>
            <shortName evidence="1">PPIase</shortName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the cyclophilin-type PPIase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000032">
        <property type="protein sequence ID" value="KAG2443125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W857"/>
    <dbReference type="OrthoDB" id="408413at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd00317">
        <property type="entry name" value="cyclophilin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044233">
        <property type="entry name" value="CYP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47511">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47511:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00153">
        <property type="entry name" value="CSAPPISMRASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033111603" description="Peptidyl-prolyl cis-trans isomerase" evidence="1">
        <location>
            <begin position="21"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="30"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="RuleBase" id="RU363019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2443125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="236" mass="26243" checksum="32F182F9D55F1ABC" modified="2021-09-29" version="1">MARKVFALLFLGAALGSAWAEEVIPVMSDERVVFQTDYGDITFGFWPEVAPVTTAHIFKLVRLGCYTSNHFFRVDKGFVAQTSDVVGGRSLPMNAEQEAEAGKTVPLEVVQGVKHHAGVLSMARGADKNGARSSFSVLLGSAPHLDMQYAIFGKVTEGMETLRKMEELPTKREGIFVMPLKRITIQATYWYRINRPEPALTLPDAKVCEDDLHELTLRFASQAEELQRVRKKCLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W9Y8</accession>
    <name>A0A835W9Y8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Trimethylguanosine synthase</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="7">Cap-specific guanine-N(2) methyltransferase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_009567</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78479"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="Rhea" id="RHEA-COMP:19089"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:78480"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="3">
            <text>a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(2),N(7)-trimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78507"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="Rhea" id="RHEA-COMP:19090"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:167623"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="3">
            <dbReference type="Rhea" id="RHEA:78508"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78471"/>
            <dbReference type="Rhea" id="RHEA-COMP:19085"/>
            <dbReference type="Rhea" id="RHEA-COMP:19087"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="6">
            <dbReference type="Rhea" id="RHEA:78472"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="4">
            <text>a 5'-end (N(7)-methyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-methionine = a 5'-end (N(2),N(7)-dimethyl 5'-triphosphoguanosine)-ribonucleoside in snoRNA + S-adenosyl-L-homocysteine + H(+)</text>
            <dbReference type="Rhea" id="RHEA:78475"/>
            <dbReference type="Rhea" id="RHEA-COMP:19086"/>
            <dbReference type="Rhea" id="RHEA-COMP:19088"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57856"/>
            <dbReference type="ChEBI" id="CHEBI:59789"/>
            <dbReference type="ChEBI" id="CHEBI:156461"/>
            <dbReference type="ChEBI" id="CHEBI:172880"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="4">
            <dbReference type="Rhea" id="RHEA:78476"/>
        </physiologicalReaction>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the methyltransferase superfamily. Trimethylguanosine synthase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000032">
        <property type="protein sequence ID" value="KAG2443156.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W9Y8"/>
    <dbReference type="OrthoDB" id="194443at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071164">
        <property type="term" value="F:RNA cap trimethylguanosine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd02440">
        <property type="entry name" value="AdoMet_MTases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019012">
        <property type="entry name" value="RNA_cap_Gua-N2-MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741">
        <property type="entry name" value="S-ADENOSYLMETHIONINE-DEPENDENT METHYLTRANSFERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14741:SF32">
        <property type="entry name" value="TRIMETHYLGUANOSINE SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF09445">
        <property type="entry name" value="Methyltransf_15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="83"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="22"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="97"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="132"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="180"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="205"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="216"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="253"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="278"/>
            <end position="316"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="324"/>
            <end position="409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="410"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="450"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="469"/>
            <end position="481"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="482"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="592"/>
            <end position="630"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00018517"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00025783"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00047418"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00048740"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00048763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00049075"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00049790"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2443156.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="825" mass="83273" checksum="435122ECCBF1EF2C" modified="2021-09-29" version="1">MLTEEELLKSMGLWQQGGGAGACDATGADAGGSSSAPQPAGATAGGSLLRGLIGGGAQGTPFDAGPSAAPALPQRVVPATALSEEQLLARMATAGGMPPPPLAPLPPAPSPMPPPPPPPPMPPPPSPPPPTAVEAAVTAAPLPAHQQKPRGRMLTEEDILRSMGLLEGGGSGATAEGDSAPHTAGAASPAGGAAGTSAGGGAGATAGPPASRSAAPLPPGFGNPPAAGPPPSSGQGHAHPHPHLHNGPYGPHGHTHGPPHHGHPPPHGHGPPHGIAGLPPPPPGFHSHGPVPPPGMPRLPPPGFGPQHPGMPPPGMAHPSNGGWPPPGGAPPPFHGAGMPPPPPGMPMPPGAPPGFGPPPPHGVHGPPYGPPYGPAPPPGYGPPMGPPGFGGPPPPGFQPPHPHGPPHGPPHHYNHHPHHGPPPHPHGPFPHAHYMGTHPPPLDLSHGPPHQHGHPHGHGHGHGHPHGRPPMPSAPPPPTPAGGEPNDQGSAAQHQQRQQPNSEAQGQGQAEDQQKHKQQQGGAAGGEGRRTAMWTLEELERQLEMLALQADVEDGPGAGGAHAHRGARGRQRGEGSAGGGGAAAAGRRSRGGNASSGSARSSLHGQATACSHQQAQQQQQQARQGRPQAHPGAAVRHGKRDGVGSGVDTAEENDDAAFYDSFAAPARRPPPPVTDMPAVGEDDGTRRITLDPNTAAYVRTLLPRSAAKYWMQRYSLFSRFDEGVQLDTEGWWSVTPEVLASHQALRSRDLAAGGRGRVALDACCGCGGNVIQMAAGVFPVVYGVDISERRIEMARHNAAVYAVLARCQFVCADFFQVAASLKAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W9Z9</accession>
    <name>A0A835W9Z9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Tubulin--tyrosine ligase-like protein 5</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_009387</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>L-glutamyl-[protein] + L-glutamate + ATP = gamma-L-glutamyl-L-glutamyl-[protein] + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:60144"/>
            <dbReference type="Rhea" id="RHEA-COMP:10208"/>
            <dbReference type="Rhea" id="RHEA-COMP:15517"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29973"/>
            <dbReference type="ChEBI" id="CHEBI:29985"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:143622"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="5">
            <dbReference type="Rhea" id="RHEA:60145"/>
        </physiologicalReaction>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443321.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W9Z9"/>
    <dbReference type="OrthoDB" id="202825at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015631">
        <property type="term" value="F:tubulin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070740">
        <property type="term" value="F:tubulin-glutamic acid ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000226">
        <property type="term" value="P:microtubule cytoskeleton organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.470.20">
        <property type="entry name" value="ATP-grasp fold, B domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004344">
        <property type="entry name" value="TTL/TTLL_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12241:SF145">
        <property type="entry name" value="TUBULIN POLYGLUTAMYLASE TTLL5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03133">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56059">
        <property type="entry name" value="Glutathione synthetase ATP-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51221">
        <property type="entry name" value="TTL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0436">Ligase</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="54"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022598"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00041448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00049274"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2443321.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="559" mass="60119" checksum="EA831F3FFACA29AD" modified="2021-09-29" version="1">MAWTLAGWQRGDSRHQAAEHAPSRGWAAGPSSAATQRARRRAHRDVLSVPRARGSGGGGGEDGGPEDGPGGGPQQRARQPAAAGKRRQFRFWIDYQAFSSAGSAELIERALVAVGGVRAGGPPKLDASTGAKRDDGVYGYMHMDSWDLLWSVTAKAALAADLLRPHQMLAIVPGLLAVSRKTTLIRSLRDMFGDAAWGIVPRSYKLPDELDEWGQWVADNPGADTGMWMLKNNKQRGTGLRLVRTSEAFTACFETVSRPDLPPGVRLYRWYLAQQYITRPMLIDGRKFGVRVWVLVSDVAPLRLYMHGRGLVLFSSHRYDAELVGGTDDGGSGGPAPGHVTNYAQNENGDVWSLVQLAAHVGAAAFSKLWADMCRAAAMAFAAALPRCAEVMEGVRPPAHSCFQFFGLDFLVDAAARPWLLEVNATPSMKVEHENPNVAALIGAQKWPAVRDMVALVGIAPQRFEEGGAGGRGAPDRSTPAYALEELRRRGGFVPLLHLLPHPAVSTTPEAAAGAGLLRPLPWGRADRVLRDWCKGSREYQAAAAEVPALGSEAALVAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WCL3</accession>
    <name>A0A835WCL3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein-serine/threonine kinase</fullName>
            <ecNumber evidence="8">2.7.11.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_008845</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="7">
            <text>L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ATP = O-phospho-L-seryl-[pyruvate dehydrogenase E1 alpha subunit] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:23052"/>
            <dbReference type="Rhea" id="RHEA-COMP:13689"/>
            <dbReference type="Rhea" id="RHEA-COMP:13690"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.2"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="8">Mitochondrion matrix</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="1 8">Belongs to the PDK/BCKDK protein kinase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.-" evidence="8"/>
    <dbReference type="EMBL" id="JAEHOD010000028">
        <property type="protein sequence ID" value="KAG2444974.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WCL3"/>
    <dbReference type="OrthoDB" id="241648at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005759">
        <property type="term" value="C:mitochondrial matrix"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004740">
        <property type="term" value="F:pyruvate dehydrogenase (acetyl-transferring) kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010906">
        <property type="term" value="P:regulation of glucose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd16929">
        <property type="entry name" value="HATPase_PDK-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.565.10:FF:000065">
        <property type="entry name" value="[Pyruvate dehydrogenase (Acetyl-transferring)] kinase mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.140.20">
        <property type="entry name" value="Alpha-ketoacid/pyruvate dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.565.10">
        <property type="entry name" value="Histidine kinase-like ATPase, C-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036784">
        <property type="entry name" value="AK/P_DHK_N_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018955">
        <property type="entry name" value="BCDHK/PDK_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039028">
        <property type="entry name" value="BCKD/PDK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036890">
        <property type="entry name" value="HATPase_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003594">
        <property type="entry name" value="HATPase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005467">
        <property type="entry name" value="His_kinase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947:SF3">
        <property type="entry name" value="[PYRUVATE DEHYDROGENASE (ACETYL-TRANSFERRING)] KINASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11947">
        <property type="entry name" value="PYRUVATE DEHYDROGENASE KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10436">
        <property type="entry name" value="BCDHK_Adom3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02518">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00387">
        <property type="entry name" value="HATPase_c"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF69012">
        <property type="entry name" value="alpha-ketoacid dehydrogenase kinase, N-terminal domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55874">
        <property type="entry name" value="ATPase domain of HSP90 chaperone/DNA topoisomerase II/histidine kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50109">
        <property type="entry name" value="HIS_KIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4 8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6 8" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3 8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 8" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Histidine kinase" evidence="9">
        <location>
            <begin position="199"/>
            <end position="329"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006155"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00048201"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="RuleBase" id="RU366032"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2444974.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="336" mass="37717" checksum="C218329BBD8A06DD" modified="2021-09-29" version="1">MLDFGQNPIERQLLLSAQFLHKELPVRLAHRVAELENLPYGLSAKKHILQVRDWYVESFRDLRSFPHVKDAADELKFTELLRGIYRRHANAVPVMAKGVSELREELRAQQRLTELPEIHQFLDGFYLSRIGIRILIGQHIALHEPPKPNHIGLICTKCSPVLVAQDAINDARSICMREYGDAPEVSVYGSPDFVFPYVPSHLHHMLFELVKNSLRAVQDRFTDSDDPAPPIRLVVAEGGEDVTLKVSDEGGGIPRSGLANIWTYLYSTAKSPVDPRQVEDADSGPVVLAGYGYGLPISRLYARYFGGDLQIISMEGYGTDAYLHLNRLGTSQEPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WFR0</accession>
    <name>A0A835WFR0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">GDT1 family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_008291</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 6">Membrane</location>
            <topology evidence="1 6">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the GDT1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446729.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WFR0"/>
    <dbReference type="OrthoDB" id="442680at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009535">
        <property type="term" value="C:chloroplast thylakoid membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005794">
        <property type="term" value="C:Golgi apparatus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015085">
        <property type="term" value="F:calcium ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005384">
        <property type="term" value="F:manganese ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032468">
        <property type="term" value="P:Golgi calcium ion homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032472">
        <property type="term" value="P:Golgi calcium ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001727">
        <property type="entry name" value="GDT1-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049555">
        <property type="entry name" value="GDT1-like_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608:SF6">
        <property type="entry name" value="PROTEIN PAM71, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12608">
        <property type="entry name" value="TRANSMEMBRANE PROTEIN HTP-1 RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01169">
        <property type="entry name" value="GDT1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01214">
        <property type="entry name" value="UPF0016"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="86"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="134"/>
            <end position="158"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="165"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="318"/>
            <end position="339"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU365102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2446729.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="340" mass="35020" checksum="6FB977B37BEE7D9F" modified="2021-09-29" version="1">MSSTQLLKNQLSQSVGRLRPGALHAPRRFVGACGLRHAVALPALKSVPHSLQRINERTVQEPVEVEVLPARSHTAPSPLSKALSSGGLLASATAVALAASLALGLPADAAAPAADTAALSIPGIVGDSPLREGFVSGFLLIFFSEIGDKTFFIALLLALKQPKGLVFTGTFGALAVMTVVSVLLGQVLHQVDELVPENGAGLPYDDLLAAALLLYFGFKTLQDAKDAGESAAEEKEEAQEVVDGLKSSSEDTLKLILTTFTLVFAAEWGDKSFLATIALAAASSPLGVTAGAVAGHGVATGLAVAGGGFLSRYFSEQVLQYIGGSLFLVFAAATIVDLFV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WFT3</accession>
    <name>A0A835WFT3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_008409</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000026">
        <property type="protein sequence ID" value="KAG2446416.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WFT3"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd12368">
        <property type="entry name" value="RRM3_RBM45"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034207">
        <property type="entry name" value="RBM45_RRM3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="10"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="302"/>
            <end position="382"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="86"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="384"/>
            <end position="413"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="394"/>
            <end position="412"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2446416.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="497" mass="52545" checksum="33386554E9EC18C0" modified="2021-09-29" version="1">MAEVDSPPGSRLFIVCGKNVEAETLQVAFRPFGNVQNVKVIREKGVAYVKYDKASSAALAMENLNGAVLNNGRGPKLKVLLAEAPNTSRGMHPPRPAEQEISSDPDNIPPRSRLFIVVPKQAEPQQINDAIAAYDGLEYCKTDLVASKGVVFCKFTKASHALRALEDVTGRGTVGPYKVKCMLAEPKTKRGRGDGSPQDMFSPLTQATKLDYGINHHLQQDAGHMGPLDLPMGHGLSPAQIGVPDYGAIGGLGGLGGLGSFHNLGDANLAVGLGHAFNMNLGSLHTNSSTVTPHDSPTLSKQRLFVVVHKTVNQDVLARLFRKFNGMEYCDLKKDPATGRSKGFCFVNYSTPEAAAAAIAQLNGIEFPPHSNQRLKVMYAEQLGVRNNNPNGPGSASHTSTGHHAAAAAAAAQVGGARSPMAMSLQTSSPSPVHTPLSGAVNLSPEAHVASVQETLANMSMPRVGSTNGVQEELEAARRMASPISSVARELMFNVAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WFU6</accession>
    <name>A0A835WFU6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">AAA+ ATPase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_008228</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446657.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WFU6"/>
    <dbReference type="OrthoDB" id="537650at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032356292" description="AAA+ ATPase domain-containing protein" evidence="2">
        <location>
            <begin position="16"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="521"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="525"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="579"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="586"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="616"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="659"/>
            <end position="706"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2446657.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="786" mass="79581" checksum="60F1BBB558135F20" modified="2021-09-29" version="1">MLKALLSVLLRWARMGRVPMKEGALAAAEADLVQPDMGTPSIVGEAIHSFIAAVEVPVLVLCDEVQSLFLPTIGSELDAAGAEYVRNRFMKRLLVGGPHTVLWCLTGSSMAHTWISVARMPPNGHSVIASASAVHLPATYSAEHMEWAWQQLQVRHSSVVLDRRLLELCPRSVALLAVLVDAWVYGGRPSDVAAFLCDFVRLKVVDESLREWKLGLESMPLSQRLTVLDLSVPAVGADIKKELHTGLQKFLEPHLDKTVDGRYYLRDSHQRQIVRLLFHSDGTLWESWSELQYSASLTQLDAGWNLFYLGEAADYLLGPNASRRWQQLAQPLPAGTDALKAKLQVIADGIANKLQAAEASVVPAAAAAGGAQQQPGGSVELGPQELWERQPWFQKVLNSNWNDRDLMAYLNNKQARPTHLAMLVFYLRLGRNVLGHTKPWDRAAGAILDVSVIEALPGVLDQPLFVFNEAMVEALRLVSATTMAAAAAEFAAELSGSVAGTSGGGPSSANVGISGGGPSSANVGISGGGPSSANVGIGGGSSQSSAKGGISGGGPSSAKGGISGGGPSSAKGGISGGGPSSANVGISGGGRSSGKGGISGGGPSSANVGISGGGPSSAKGGISGGSSQSSAKGGISGGGPSSANVGISGGGPSSANVGISGGGRSSAKGGISGGGSLSSGKGGTSGGGSTSRGGGRGGSRGGGGRGRSARAVPDQYTSPPVGPAAAAGCSQRPPLLSTASGNCVGWGKGGQRAPTLAPSRRVRLPLVAQAIPAAAAAMGSRLLRGC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WG54</accession>
    <name>A0A835WG54_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008281</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446718.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WG54"/>
    <dbReference type="OrthoDB" id="546586at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="54"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="587"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="136"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="146"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="195"/>
            <end position="219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="226"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="418"/>
            <end position="427"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="449"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="470"/>
            <end position="483"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="507"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="518"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="546"/>
            <end position="555"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2446718.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="587" mass="57509" checksum="11511033E8A9996B" modified="2021-09-29" version="1">MPLVPHTLLFGCYFDWANSVGEFTTSTERSNAIRVIDGMTYEGAKLRCEPLHMEDGPDAVEERGAPAASDRYDGGAPDRTGGGGGGGSYHKSERAAGGGHEEKSYPREERRAAGGEKAAAAGGGYDDRYGYDEPYEGGGGGGGGYSSREGGRAAAGYEGGGGRAVPAAGGGGAAYDDRYPPEKYSRGEYPPTSGRGAGYEGGGGRGAGYYEGGGGGGGYREPAYREGGGGGRGGGGGGGGYEGGRGGYEGGRAGYEGGRGGYEGGRAGYEGGRGGGYEGGRGGYEGGRGGYEGGRGGYEGGYSSREAGYSSREGYGPAGGGGYREPARDADYGPSGGRGGAGYDERYPPAKYARTEYPPAAGGGGRGGDYWDGYEGGGRGGGGGGYEGGYEGRGGRGEPGYGPPPAKGDGYAAGPPSRSERGADYGRGDGYAAGGYPAREAGYGGSARGSGAAAAGGSTRDAGYYERGYEGGGGRGGGGGGYERGYDRGYDRGYDRGGDYYDEPGYKSGGGGGGGYGAPASRAPPAAGGAPAAAAAAPTGSGGRGAAAAYPADAGYEGSGRGGPDRSYPPARSGGGGGGGYERSAPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WG62</accession>
    <name>A0A835WG62_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_008002</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000024">
        <property type="protein sequence ID" value="KAG2446845.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WG62"/>
    <dbReference type="OrthoDB" id="536365at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033029373" evidence="2">
        <location>
            <begin position="16"/>
            <end position="175"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="48"/>
            <end position="67"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="74"/>
            <end position="94"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2446845.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="175" mass="18457" checksum="81669B80A18D27E0" modified="2021-09-29" version="1">MAAVVCAFAVMLSAAIFVSHVLRTGQQVDSIITYLSQALWVDTAFNEYTFVAQCFFTALAVVLYVCLNYPGTLAWVLAGLCGLMVLSLLVMVLWSTTIFHATGQREWDEIVAAEEEFRAYAKATAVAAPSNGGCGEAGCGAELEVKAAALHRQSAAKAANDKPRVAADIGSDGDG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WGU0</accession>
    <name>A0A835WGU0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447190.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WGU0"/>
    <dbReference type="OrthoDB" id="524901at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2447190.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="223" mass="24587" checksum="4348EF2A1BEBC5F7" modified="2021-09-29" version="1">MSPAPTPPPPKYPPFDKHRPRGWLTPEPQVTGSNVFFPDLDYLQAALLQGRVPPQELDQPRATLNLSLFTTTTRSGTKALDLFKSTGVTWKIPKGFLNRYNDCNHEVLRRAAALAGAKHDSARDVVAGVWGRVDVPTFVEACRQVMGELSAEEEEYLIALASEQVQDGTSLIRDLPFLDKCIQNGKTPTSIKGPELLPTIFLNDTTSGKTDGMMLRHTGGRIF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WH64</accession>
    <name>A0A835WH64_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">6-phosphofructo-2-kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_007783</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000022">
        <property type="protein sequence ID" value="KAG2447462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WH64"/>
    <dbReference type="OrthoDB" id="267323at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003873">
        <property type="term" value="F:6-phosphofructo-2-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004331">
        <property type="term" value="F:fructose-2,6-bisphosphate 2-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006003">
        <property type="term" value="P:fructose 2,6-bisphosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006000">
        <property type="term" value="P:fructose metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:000644">
        <property type="entry name" value="GpmB, Fructose-2,6-bisphosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003094">
        <property type="entry name" value="6Pfruct_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013079">
        <property type="entry name" value="6Phosfructo_kin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606:SF44">
        <property type="entry name" value="6-PHOSPHOFRUCTO 2-KINASE_FRUCTOSE 2,6-BISPHOSPHATASE LONG FORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10606">
        <property type="entry name" value="6-PHOSPHOFRUCTO-2-KINASE/FRUCTOSE-2,6-BISPHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01591">
        <property type="entry name" value="6PF2K"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00991">
        <property type="entry name" value="6PFRUCTKNASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="6-phosphofructo-2-kinase" evidence="4">
        <location>
            <begin position="84"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="23"/>
            <end position="34"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01591"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2447462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="319" mass="33782" checksum="0F674576C0D80797" modified="2021-09-29" version="1">MPPSCAETESGLGLDDADEADADAATGLASAPSGSAAAGATVEALATAGPSGSSGGAGAAAGCEGEGSSGLGQVGGGARVRSSGTVVRKNKLIIIMVGLPGRGKTFLCNKIVHYLNVSATLGHATRHFNVGAYRRIQKGAHEVQSAAFFDHNNEAGMEARNRALNAALDDLVSWLRTDSGQVAVFDATNTTESRRNLLRSKFHGHFQYLFIETICSDPAVLEQNYRNKMKYSPDYKGVDVDQAVADFLARIAKYEEVYEPIVDRNLHYIKLTDMVTGRGYMDINRISGYLPGKIVFFLMQVRSSACAFASVFRATGGAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WH75</accession>
    <name>A0A835WH75_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">FAS1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_007684</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000022">
        <property type="protein sequence ID" value="KAG2447356.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WH75"/>
    <dbReference type="OrthoDB" id="544886at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005615">
        <property type="term" value="C:extracellular space"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="FunFam" id="2.30.180.10:FF:000094">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.180.10">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050904">
        <property type="entry name" value="Adhesion/Biosynth-related"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036378">
        <property type="entry name" value="FAS1_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000782">
        <property type="entry name" value="FAS1_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900:SF77">
        <property type="entry name" value="FI19380P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10900">
        <property type="entry name" value="PERIOSTIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02469">
        <property type="entry name" value="Fasciclin"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00554">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82153">
        <property type="entry name" value="FAS1 domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50213">
        <property type="entry name" value="FAS1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032281836" description="FAS1 domain-containing protein" evidence="2">
        <location>
            <begin position="31"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="103"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="domain" description="FAS1" evidence="3">
        <location>
            <begin position="287"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="38"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="82"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="83"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50213"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2447356.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="378" mass="36979" checksum="24F73C494DE0EB02" modified="2021-09-29" version="1">MGHTHRAPALAAAALLLVVLLGCSVGTASAAGRRALLQGEPPQQPQRGDEAGGTGGASAAPLPLQLPRTPASSAEPVLLSPLLPLPASPSPPPPGPVAADDAPAAVNATSEMPPNATVAIDAYNVTGAAAKVAANETSAVSTIFAPTDAAFADLAAALGLASPVDLFNATLNGTAANITALHVIPGVALTAANITAAGNITATSLLGYNITVSALPNGTVTATIPGSNIVADVITPDVPFNGSIVHVINKVLLPPLNETAGWTVPIANATAAVTDAQPAAQKRNPAAASAPSPAASSPPVGIAVEALNATGVASLLNASTVATIFAPDNAAFISLASQLNMTSRYQLFASPFATNVTLLHIIPGRLGGAMVCVCGAGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WH80</accession>
    <name>A0A835WH80_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">PHD-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_007941</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447199.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1903104at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003682">
        <property type="term" value="F:chromatin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042393">
        <property type="term" value="F:histone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000977">
        <property type="term" value="F:RNA polymerase II transcription regulatory region sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045944">
        <property type="term" value="P:positive regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016181">
        <property type="entry name" value="Acyl_CoA_acyltransferase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056511">
        <property type="entry name" value="IDM1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032308">
        <property type="entry name" value="TDBD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011011">
        <property type="entry name" value="Znf_FYVE_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001965">
        <property type="entry name" value="Znf_PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019787">
        <property type="entry name" value="Znf_PHD-finger"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47025">
        <property type="entry name" value="AUTOIMMUNE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47025:SF2">
        <property type="entry name" value="AUTOIMMUNE REGULATOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23209">
        <property type="entry name" value="IDM1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16135">
        <property type="entry name" value="TDBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00249">
        <property type="entry name" value="PHD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55729">
        <property type="entry name" value="Acyl-CoA N-acyltransferases (Nat)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57903">
        <property type="entry name" value="FYVE/PHD zinc finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50016">
        <property type="entry name" value="ZF_PHD_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="PHD-type" evidence="8">
        <location>
            <begin position="1887"/>
            <end position="1947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="12"/>
            <end position="72"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="87"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="348"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="445"/>
            <end position="888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1041"/>
            <end position="1061"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1073"/>
            <end position="1151"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1210"/>
            <end position="1283"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1402"/>
            <end position="1446"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1618"/>
            <end position="1705"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1821"/>
            <end position="1840"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1855"/>
            <end position="1880"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2269"/>
            <end position="2309"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="2351"/>
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    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2502"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2594"/>
            <end position="2615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="2640"/>
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    <feature type="region of interest" description="Disordered" evidence="7">
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            <begin position="2735"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="2832"/>
            <end position="2913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="16"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="144"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
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            <begin position="187"/>
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            <begin position="2269"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
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            <begin position="2597"/>
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        </location>
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            <begin position="2641"/>
            <end position="2650"/>
        </location>
    </feature>
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            <begin position="2742"/>
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        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50016"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
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            <dbReference type="EMBL" id="KAG2447199.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2913" mass="288914" checksum="997ADDCF190285D8" modified="2021-09-29" version="1">MEGAEDVLRAAVVVGDGDRQPAPELAEEHDAAAPGQVPTANTALRAASPDGTSEAAAQQGADERKNKASTTHVAEALATSAAAMGQVPAGVASADDPAQPTNHQGSAPTDAEAMPCAGPSAAAVPQDPSQQQTSDEGDRGCPKAAPAEAAAGQVAAAAPASKQQPDAAGAPPSGDDKAMQMEPVPAPDGDGADAQAQLAADETHVAASAATASAAGEAATAVEVEGSNVPHAKEEPADADAGVVKAEHGGEAATAAPVSHSADADSGGPVGVQDAEHAAEPGAADAANTTAAAGSGPQAEPLAEKPAQGAPGNGPGSAFAMGLLGPNPDAAVGAVMYDLWANEGSVTGLTGSKRRGGATAPAAPTAAAARSGGGGGPPPAKRAKQEAAALRAADISKAPAKTAAASSGRRPARSAAAAAATTAAEAEAEAKPDAVAKSAAKLKGKAAADDAVGPSKLPATAKGKAAGKMGEAGADEGTTADAGKATGAASKKEEAAASKKGKAAAKKGEAADAAAGDAAEDKKGKAAAKTGKSETSAGVKQEAVEPQTSGPAEAKRGAASKGKGVQQAKKKDDAAGASAAAALASESKDVKAEPSAAKPQGKRKAATASGKKGKAVDGKDEAAAAPKEEKEEAGAGPSTAAAADSQATESGKPATSAAAAPEKQEPSAKSKRGAAAAEAKKPGARTSSRKTASASVVSKDNATAGGTSKEATSPGEGAKAAPAAAADVDMKDAGEKADEPAATGGGSEGAKDAAPIADGSKGEAGGDKEATAAASKPGERSTRLPRRSKLLKATPADSAAAKPTADAVATTTAEPAADAAGTSDKAAGGEGAAAEAATASIKAEAADEPATQAAAAAAATADDGETSKPARQPPPPGPPGFTEDPDWLDWPIKLTDDHVDFIRKLAHKVFLAKEAPPRDAKALLRCSGMWGRKLEYRKRDGREGTYRPIYSGIVTDKGTLACTCDACKQEKTHSLTEFEVHCGGTHKKPADHTWVIDLGLNLRDLALMTCRCLGLGHIAAGTGQGRISGAAVKAALGESALGTGEGKKRGGGGGGKPRKSAAAAAAADGEGGAAALVSPRARGTGSSPAGRKAGRPKAAGSSTETESDAETETETEDDLDEFEEPVERTVPTGGTARQRAAAAQEAAAAADRHAPVPVGTCTVCLRALPENYKELAAEPVNATVLECPKCHGHCHTSCAAPFGLPPPRPAPAPAAAAAPDAAPAADAAAGQPAVVSEQAAEGAAPSTEAAAPPAQSTGPAADATAPAADAPPAADTAPSGAAADTVMTEAGSALPPAADAPPAAAEAVAVAAAPAPTTAEGEAAPAAAGADAAAAPVADVPADITATVAAAAPSAAAPAEATATAAAAPAEAACDWQCPHCRQVGRGKRMKRPNPTYLDQDSAAAAAGAGPAPDRPGRGRGRGSRPPGSGAVAGGGRGRGRGRGRNIMNMTQAEIAEMYFAKARMAMAKGGDGSVPKPAASSGAGAGGMGGLVGAPLAGGAALPGAAAASTAGTVGPSSDAAAAPSVIGDIAPPAAATVPGADSTAAAASAEGAAAQAQGAAPVDTAAAGADTAVPVSAGDGAAAATPAGGDAEAAARAKREQEDAALARAIAIAEGWGGGGEEYGEEYGEDEEEEEEEEEEAVDDDDEDYEGGRRRKRLKGASAPPPRTHFSIAPPTLQHPAASPASRPAAGAAPPPPGGGRIQMTLPVTMRASAARSNASARRQVCGRTLFDGLPGGLKHDDVVWYTLQGKRLLRGVVQLQSCGAPSSGILCGHCNTIVSASAFEAHAGHKHRRNPYEAILTDDGMTLKRIAERLVPVAASQAGPASPPQPRSKAGSGALAAAAAAAAAAASAAAAVQHDQQHHHQHHEAGEEEAEEEMVDLVDDAACVLCHEPEFDREGFSDKTVLICDQCEKEYHIGCLRQHKMVDMQAVPEGEWFCSDECVRIRDALSEDVAAGEVLTPGNPAYRWQILRGKNGKQQTWHALSTVLSILQESFDPIIDTGSGADLLPAMVYADTAGDYDFQGMYSILLRYRGPDKEARGKPVLAALFRVLGSSMAEMPLVATRYDCRRQGHLRALVDALRHKLLGLGVRAIVLPATADAQPAWRQLEFQDLDEPSTRVARSEHRMVIFPHTTVLARPLIRVPGYDQSQLQSAQEATDSAFIAACGKAMEEARAASGKEIVESEEKIYAAMDAAAAAAAEVQAAKAAALAERGIFPGRRGGRGRGRGRGRGLAAAAPGGYGAAYAPGPMEVDAYGPPIPGSGGLEGEPYAGGMGPYPGVPPHLALLPGSPSATGRGRGRGRGRRGRAHLGAYAAYPGHPGADMGDPAAAGYSGAVAEVEEGAMAYGPGGWGGHSMPMPSSRGRGRPRGRGRGTGAGPGRPRGRGRGRGRGRAAAAALYAGGVAGAGSTYPAYDAEGAGEEDEGEDGDDTWAGYGGVGEVASAVGSAVAAGETGEGMMAAAMGAASRFSMGPLQGAMVAAAAAAAAAAAKQYAPQMAAADAAGRPRQPSDGAGAAGIQPAPFGMPQQQQQQPGQLPGAPGLAAFSAAASGAPAAGMPGGFGLDAAGQAGAQAPAAVAAAAAAYKWALEQFTQKQQQQQPPAQTASAGPPGGGAAAYGMAARAYGNALNVGMAPTAAPGRGGGGGAPSVGGWNQPQGWPQPQQVQPAQAHYQPPAPQQQPQQPQQPQQPQQPQSMQPSQQQLQACNFLASLAGGSGLSGGGAAPGPAAGVSGGGWVAPAAQPPPAAQHPYQPQPHHQPPQQHHHHQPHQQHQMHGSMVSYHQPHQPPMPAAQPQHYHQPPSAWPQAGVGGGNPSLTDQNYHETLAALQRQQERQNQQTLMGIPPAQQQQHQQFPQHAGYPSGMAPPPQPPQQQQQYGYPDPQAQAAAQFAAYGQYGPSGGAPGLFGQQPQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WI60</accession>
    <name>A0A835WI60_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Rhodanese domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_007523</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447601.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WI60"/>
    <dbReference type="OrthoDB" id="566238at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00158">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.250.10">
        <property type="entry name" value="Rhodanese-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001763">
        <property type="entry name" value="Rhodanese-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036873">
        <property type="entry name" value="Rhodanese-like_dom_sf"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00581">
        <property type="entry name" value="Rhodanese"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00450">
        <property type="entry name" value="RHOD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52821">
        <property type="entry name" value="Rhodanese/Cell cycle control phosphatase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50206">
        <property type="entry name" value="RHODANESE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Rhodanese" evidence="2">
        <location>
            <begin position="87"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="90"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="230"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="59"/>
            <end position="77"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="239"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50206"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2447601.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="273" mass="29017" checksum="6593FB664333D82D" modified="2021-09-29" version="1">MGREPPVNKDAKAAAAADPAAKLEELYRGFAHRFEGVPEVTAQEVYAWITSSQQVAATDPQQGSILSGSEQQQAGPLSSSSSPPPPPPPAVVLVDVRSHAEQQVSVLPGSTTLTQKQFEARGPETFHGVRVVCYCTAGYRSGMYAAKLRRCHSHLQVYNMRGSILAWTQAGLPLADPRDGSHTKRVHVFSEGWALQGDGYEPVVFRRPLVSLALDSVGAAAQGLLRAVTGGGGRHRHAAAAGAQAQAQQPQQPQQPQQGHQQEPSGKQLGVDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WI83</accession>
    <name>A0A835WI83_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">EF-1-gamma C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_007775</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000022">
        <property type="protein sequence ID" value="KAG2447450.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WI83"/>
    <dbReference type="OrthoDB" id="249703at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003746">
        <property type="term" value="F:translation elongation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1010">
        <property type="entry name" value="Translation elongation factor EF1B, gamma chain, conserved domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050802">
        <property type="entry name" value="EF-GSTs"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001662">
        <property type="entry name" value="EF1B_G_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036433">
        <property type="entry name" value="EF1B_G_C_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43986:SF1">
        <property type="entry name" value="ELONGATION FACTOR 1-GAMMA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00647">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01183">
        <property type="entry name" value="EF1G"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF89942">
        <property type="entry name" value="eEF1-gamma domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-1-gamma C-terminal" evidence="2">
        <location>
            <begin position="190"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="88"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM01183"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2447450.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="367" mass="37174" checksum="7D34C8A2DED91E47" modified="2021-09-29" version="1">MGCGASTHAQVAQKARGSQQESGGAPVPVAEDARAPEQLIGQTAAGPGVVSDGVTPKGLQGRISGVEAGPANGQQQQDGEARAFNGNGNGNGGLAIALHGTEGPQGSGYEAAADANSNGGGSLLDPAVTPHGGTATVTLGLGGGGGGVGGGGGGGESAAHGFNARSRYTNQSELSMASTSYDLSGRGDSDSEDELEALFTMASWKRFYSYNKKKHHDLLTYFWRKFPPSGYSLWCVSYRYGDLLLAPFMADNVAAGYMARLEELPALAGGGGGGGGGDGGGAHLADEVFCQMYSLHDYEMDEYRVVGLLLAPGSALPTALAALSAFDGFTYLKADSGSTHVKQFVSALLVGKSPLTSLSLLSGREVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WI99</accession>
    <name>A0A835WI99_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_007342</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000020">
        <property type="protein sequence ID" value="KAG2447887.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WI99"/>
    <dbReference type="OrthoDB" id="20872at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017907">
        <property type="entry name" value="Znf_RING_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24171">
        <property type="entry name" value="ANKYRIN REPEAT DOMAIN-CONTAINING PROTEIN 39-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12796">
        <property type="entry name" value="Ank_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13920">
        <property type="entry name" value="zf-C3HC4_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00248">
        <property type="entry name" value="ANK"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50297">
        <property type="entry name" value="ANK_REP_REGION"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00518">
        <property type="entry name" value="ZF_RING_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 7" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="6">
        <location>
            <begin position="83"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="9">
        <location>
            <begin position="1088"/>
            <end position="1129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="357"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="578"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1035"/>
            <end position="1081"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="357"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="8">
        <location>
            <begin position="373"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="578"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1056"/>
            <end position="1065"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2447887.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1176" mass="113560" checksum="F6422805D9F2F81F" modified="2021-09-29" version="1">MVACKHGHPDCVEYLVTNGGDPLLTDERRHNTCLHFAALYGHSECVHKLLGSRAAYRVQVPVAQITCVDDGTTTKFIDRHNGWGLSALHIAVFQGSVSTVRALLRHGADLESVICASKVENSPIRCAVGSNALHIAALTGNIIMAKLILEQQETFPGLELRSRTNAAGLKPGDYAQSARNPVLIHLLDERLPVTLLRQIWMNYSLEQSLPPRHQTLGSMLQKLKLMFNLELISIQRNITYLAAQQQAAATQQQQQTMTTAEAASGTATPAKPASAAAAAAAVAPAAAPAPATPASPKGAADAGAAPVALVADASAPGGTAGTLTQSPTAAAATATTAATNGGALASAAATPAAASTPVAPATATVPASPAPKQAHHHHHHHRGAGGGAGMEPANVRLLWARRQEEITQLLATVTALHDSLKQLCRRDDPSGEEDPAGGPSRADRAATYEAVLDFILSTLITPRTVSAILHAAKKLVSASVTGSAALAAGGAPPELPPADSDSQHGLALLSTALRAVETCLQAAVFLTSPAALEQQPQPAAAAAAGTQPGATANAAADGIASDPVVAAGTQAAAPVTAVASTDASPTSGTPRAGAAEAPATATPAAVTPDATPPAAAPSHAASATLVSDPLASIAPASASGGAASAAPPGSVAAAGLAGGVSSPRAAAIAAAAAGAVSVLTGGTPLSTGHATLLMPAAAVGAGAGGRPGPGPGFMTVDGISPNSAFATHWSAHLHTLIAQLQWDIGVQRHRRRRAHAAAAAARSAAAAAAVVAATANATTANTTTANAAAPATANGATAGTPTAAPPAATAAGADAATATAAGGAAVAAASAAPATLPEVRVVRAPAPNAAGNAADAAAADTGAAPNAPAAHLLRAISSRRGDAVQDIVTSQTRGGATTVTAAAGSGSDSGVSTPVAGRGAAAATAAAAAVVVAAVAAADGASPAHPEAAAGGDPQVATVTGAVITGGVIRTDEIIPLVSGVFPHPRAATGAADATAGAAAVSPATPGAAAAEPPVASATAAAAAAPVTAVAAGSKRGAAATPSKDAAARGKDSGAAGAGDAGGLDGPDDTPGVSDSGSEWSDDDRNVCSICMDLPVAVLVAGCQHGLCVQCAFQLCVKGRELPSCPFCRQKIGGFEAKEVVAAAAAAAGAAAGAASAGAGAGAAVTRAGAAGGARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJY1</accession>
    <name>A0A835WJY1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_006125</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000016">
        <property type="protein sequence ID" value="KAG2448772.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJY1"/>
    <dbReference type="OrthoDB" id="546618at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38663">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR38663:SF1">
        <property type="entry name" value="L-ORNITHINE N(5)-MONOOXYGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="83"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="219"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="314"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="98"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="230"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="323"/>
            <end position="337"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2448772.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="377" mass="38628" checksum="5AFA821D07FDCC45" modified="2021-09-29" version="1">MVTFPTRYAPQVKQFDVDVHWLGRMRQAHLHDFSRQPGGPAARLAALRAAVGGGSATPEAVAALRALQAKGVLRVEEEVEVEAADWSDRQGQRQHSRGCSSSSDDSCGSDNEDGDDGSEGGLLLHADHVWCATGSVVDAGRDPLLRGLAEQCPVQLHGGLPELTPELRWCEGLDVFVAGAYAALRLGPGAGNLMGARTAAVRLVRLWQREAGASLCPYFKAPLPPPPQPQQQQQQQQQQSAAGYEVEADDGAVGPLTRVAAAPLRGASAAAAGSSRRRPKGRKATGVAGAAAGAVSAVGTAIVAQATVAAAAEQGPEPAGHMAPGGDGAGTDAGAVGGAAAPEQQQQQQQVLAVCERQALCYCDAIVRPGANSSSAA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WJZ6</accession>
    <name>A0A835WJZ6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Tubulin delta chain</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="12">Delta-tubulin</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HYH02_006829</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="13">Acts as a positive regulator of hedgehog signaling and regulates ciliary function.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="3">Cell projection</location>
            <location evidence="3">Cilium</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Microtubule organizing center</location>
            <location evidence="1">Centrosome</location>
            <location evidence="1">Centriole</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="4 14">Belongs to the tubulin family.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000018">
        <property type="protein sequence ID" value="KAG2448245.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WJZ6"/>
    <dbReference type="OrthoDB" id="10250004at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005814">
        <property type="term" value="C:centriole"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005929">
        <property type="term" value="C:cilium"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005200">
        <property type="term" value="F:structural constituent of cytoskeleton"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030030">
        <property type="term" value="P:cell projection organization"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007017">
        <property type="term" value="P:microtubule-based process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02189">
        <property type="entry name" value="delta_zeta_tubulin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1440">
        <property type="entry name" value="Tubulin/FtsZ, GTPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002967">
        <property type="entry name" value="Delta_tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008280">
        <property type="entry name" value="Tub_FtsZ_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000217">
        <property type="entry name" value="Tubulin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036525">
        <property type="entry name" value="Tubulin/FtsZ_GTPase_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017975">
        <property type="entry name" value="Tubulin_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003008">
        <property type="entry name" value="Tubulin_FtsZ_GTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11588">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00091">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01224">
        <property type="entry name" value="DELTATUBULIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01161">
        <property type="entry name" value="TUBULIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00864">
        <property type="entry name" value="Tubulin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55307">
        <property type="entry name" value="Tubulin C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52490">
        <property type="entry name" value="Tubulin nucleotide-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00227">
        <property type="entry name" value="TUBULIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="11" id="KW-0966">Cell projection</keyword>
    <keyword evidence="8" id="KW-0970">Cilium biogenesis/degradation</keyword>
    <keyword evidence="9 14" id="KW-0342">GTP-binding</keyword>
    <keyword evidence="6 14" id="KW-0493">Microtubule</keyword>
    <keyword evidence="7 14" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Tubulin/FtsZ GTPase" evidence="16">
        <location>
            <begin position="37"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="15">
        <location>
            <begin position="241"/>
            <end position="321"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="15">
        <location>
            <begin position="252"/>
            <end position="266"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00004138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00009636"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00014184"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022701"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022794"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023134"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023273"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00030594"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00046149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="RuleBase" id="RU000352"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="SMART" id="SM00864"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG2448245.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="521" mass="54727" checksum="DFE1DA5F0AB3646D" modified="2021-09-29" version="1">MPTITLQLGQCGNQLGCSFFNTLATEFSSHDYGTEAVHEYYRPSPDPNLYTARSVLIDMEPKVVAGARSAAAASGSWWRYPSAGYLVMQSGSGNNWAQGFHGYGPQVHDDAVELVRKEVEQADSLTGFLLLQSMAGGTGAGLGTYVAAALRDEYHSAFIANCCVWPYESGEVIVQPYNTLLTLSHLADVSDGLVLLENEALHRTAAKLYGIARPSFGDMNGIAARALAAALLPSQARGPYAGGAYTPPAPQHQHHHHHPAHGHAAGHGRNSPGSGSTGGGSGVQLPALRRADSSGGRLGGESPGLGSRAGSATPPPASGGGGSGFGVCTAPLAELLTRLCGHPAYRLLTLRSVPQLPPANIDFTTFTWPALTKRLRQMLVTGSVLEEGLDWSITPQSPGSAAAAAAGPGLAGPSVNRALASWLILRGQGAGEVDVGDFADPALTAAWSAEPLAVSYSAGRFGRCAMSACLLSNDRRMQEHAYGMLESRAFVHQYEKYGLSVADFQECFARIEDIAQRYARL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WNA1</accession>
    <name>A0A835WNA1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_004642</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000010">
        <property type="protein sequence ID" value="KAG2450807.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WNA1"/>
    <dbReference type="OrthoDB" id="437790at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060287">
        <property type="term" value="P:epithelial cilium movement involved in determination of left/right asymmetry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055289">
        <property type="entry name" value="OFD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39063:SF1">
        <property type="entry name" value="OFD1 CENTRIOLE AND CENTRIOLAR SATELLITE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39063">
        <property type="entry name" value="ORAL-FACIAL-DIGITAL SYNDROME 1 PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="125"/>
            <end position="305"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="325"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="19"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="125"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="158"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="170"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="343"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="402"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="460"/>
            <end position="472"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="512"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2450807.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="641" mass="67716" checksum="C83F6F27CBEDC49C" modified="2021-09-29" version="1">MQEIRDRSAAILGHAGATLSGGSGAGSPIGAGGGFGFYHGQQQSGGVPMHPPQSQGGMFQGPQGSQQGDTPPYMTYVMHSTPYGQQVQQPQQGMTPRAAAAAEAAARAQFMEAQHQQQQQMMFEYAQQQHHHQQQQQQQQQQREMYMRQQQADAEAEAQQRDREELAFLRQQQQQQQQQQQARDQQPPQQQRSQSGPGQGQQQQRPPQYLTPQHQEEQEEQEDPRVDFPFLTHNGGAQDDDAPYPHAIQRHNSGSGVAVPPPTPQEVPTPVHEPATEPPRGASPDRGAAHVSFSDPPATQVSHPGLRDMQAFGSMRSSVEPFAAADAAGAAGGASTAASQPAAPVAPPPGLVLTSSLGSQPAQPIEEEEAPPPPPPKPIIPGLVMVSGFTPRGTAAGMTAPAAPPPPPPPVEEPPLPPPPPPPQDVESVMQAKMRMLQEQRERALAAQVAPIRRLQSQKSASSRASTSTSAGGAAGPYLPGSPSTSSPGMDTRPGLLPREDSNSELIAREAEDTVAPELSTITSRRVLLRRSSLDSGVGGPRGNSRRELKTSVSFVRSEASGLSTPLEAPGAGSEILRGHGGGHSMRSIALGMTLDEIPSSLGDADYQLPGLGDDDDGVEAPEELGGYGNFAAEFSAGSVF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WNB2</accession>
    <name>A0A835WNB2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Sugar phosphate transporter domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_004657</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000010">
        <property type="protein sequence ID" value="KAG2450822.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WNB2"/>
    <dbReference type="OrthoDB" id="6418713at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004853">
        <property type="entry name" value="Sugar_P_trans_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050186">
        <property type="entry name" value="TPT_transporter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11132">
        <property type="entry name" value="SOLUTE CARRIER FAMILY 35"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03151">
        <property type="entry name" value="TPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 5" id="KW-0472">Membrane</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 5" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="6"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="43"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="67"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="159"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="5">
        <location>
            <begin position="235"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="domain" description="Sugar phosphate transporter" evidence="6">
        <location>
            <begin position="6"/>
            <end position="267"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="Pfam" id="PF03151"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2450822.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="301" mass="32032" checksum="8ABE44BFD1290C82" modified="2021-09-29" version="1">MVDLKFSYPMAVSVMGMAMSGLLGFICCRVLRLVEAHAVVRWRFWFTKILPIGFFMAITLWTGNEVYLYLTVAFIQMLKAFTPVVTMLCLFVARLEDPTRAMVASVLLTATGTAVAAYGEVRMSVVGLVLMFSSETAESIRLVMTQFLLVGLKFHPIEGLMYLAPACSLWLLAGCAAVELRTIVAKGHLAIVAANPGLFLCAAVMGFAVNTLAYTTIKLASSLTLKVLGTVKNTLLVVCGVLFLGELVTGLQGLGYLISLAGFAWYNYVKAQQIASGGGVAGGAAAVPAPLEGRSSAGGRH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRH6</accession>
    <name>A0A835WRH6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methyltransferase FkbM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_003018</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452788.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRH6"/>
    <dbReference type="OrthoDB" id="5835829at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006342">
        <property type="entry name" value="FkbM_mtfrase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052514">
        <property type="entry name" value="SAM-dependent_MTase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01444">
        <property type="entry name" value="fkbM_fam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203:SF13">
        <property type="entry name" value="EXPRESSED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34203">
        <property type="entry name" value="METHYLTRANSFERASE, FKBM FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05050">
        <property type="entry name" value="Methyltransf_21"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Methyltransferase FkbM" evidence="1">
        <location>
            <begin position="57"/>
            <end position="205"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF05050"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452788.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="227" mass="24918" checksum="4D0B19E2CF44152E" modified="2021-09-29" version="1">MLRSNTSDFAVLEQHVCNCDFCSLGRQLPLERHAVTSVLDLGGNCGLAATVFAAVYPNARVVTVEPGTSTFQLLAVNTAHNRRIQAVYGAAWGSSTLLTLAGAIYDHSAKQDATDWATSVGPLQSAAASVSDLVPAWSVDDLLAKYHLGAVDVLKVDVEGSEAVMFRDSKTVQWLRRVKCLVIEWHHGFLTDKQYDKFLAIMDRYGLKPLGRFGEHEGFCRPQELKH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRJ9</accession>
    <name>A0A835WRJ9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">IMP-specific 5'-nucleotidase 1</fullName>
            <ecNumber evidence="4">3.1.3.99</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_003209</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>IMP + H2O = inosine + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27718"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:17596"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58053"/>
            <dbReference type="EC" id="3.1.3.99"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subunit">
        <text evidence="3">Homotetramer.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the ISN1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.99" evidence="4"/>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452177.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRJ9"/>
    <dbReference type="OrthoDB" id="185373at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008253">
        <property type="term" value="F:5'-nucleotidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000287">
        <property type="term" value="F:magnesium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006190">
        <property type="term" value="P:inosine salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071590">
        <property type="term" value="P:nicotinamide riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071592">
        <property type="term" value="P:nicotinic acid riboside biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009117">
        <property type="term" value="P:nucleotide metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009453">
        <property type="entry name" value="ISN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28213:SF1">
        <property type="entry name" value="IMP-SPECIFIC 5'-NUCLEOTIDASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06437">
        <property type="entry name" value="ISN1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-0546">Nucleotide metabolism</keyword>
    <keyword evidence="7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005307"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011881"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012894"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00015544"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023080"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00047413"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2452177.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="480" mass="53608" checksum="CAC5431BD40E532B" modified="2021-09-29" version="1">MLHRAHTKATYVTSGRQCAGRSCVARPLLPAQRSVRDVALATAAPPAAGSTSQAAQAPAAPANGAPSPAALTGGPVAEVNIGYWELLNTAESGEVFSQRARSASDAAVLRRKGHLKEQDRLIDFMRRMHETHTCEEVMLKMERWIAEHRQDPKRSRLRRLIPGIGIFFTPLKLVEAFREYDAFFALSRRKYIPPNFAELRHVVNIAQVHASADTLKLITFDADGTLYADGAHMEQDNQMIAHIINLMRSNVQVAIVTAAGYPGEPEKFEKRVMGLLEAFRKLKLSPEVTSRFHIMGGECNYLLRVRPDDKRLEFVPDNEWKTATMQSWKEEDIVALLDEGEAMLQEGAKRLNLAVNVIRKNRAVGIVPTQPTIYEVLEDIALTIQTQLVAKVPFCAFNGGNDVFVDVGNKLLGLEALMRYLQVAPPEVLHVGDRFTDSGNDVATRDICSVLWVANPEETGFFIKMLLKDIRKSRWQPYIE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WSJ0</accession>
    <name>A0A835WSJ0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Hydroxyproline O-arabinosyltransferase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_001627</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453403.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WSJ0"/>
    <dbReference type="OrthoDB" id="2016014at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056508">
        <property type="entry name" value="HPAT-like"/>
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    <dbReference type="InterPro" id="IPR044845">
        <property type="entry name" value="HPAT/SRGT1-like"/>
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    <dbReference type="PANTHER" id="PTHR31485:SF17">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31485">
        <property type="entry name" value="PEPTIDYL SERINE ALPHA-GALACTOSYLTRANSFERASE"/>
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    </dbReference>
    <dbReference type="Pfam" id="PF23452">
        <property type="entry name" value="HPAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="domain" description="Hydroxyproline O-arabinosyltransferase-like" evidence="7">
        <location>
            <begin position="82"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF23452"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2453403.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="408" mass="45371" checksum="31B7FD0D155D163E" modified="2021-09-29" version="1">MRKGAKAEPVTNWHRAGAILLGVLAGYVVGGAVMETADMFYSTPVTPKGGASSGVKIMADGSPTTSAATKTADTRPAGDTIHSVITGNGSPYQNFQGRIMYGTYKLVQKMPGGEKLTGFTRILHRMKPDEFMDEIPTFRANPLHPKCDEWCDFPVADRPNAVAQWIAAAAKDPSMIKGAWILLLECDYVWMRPVQAPDAYDSKTVGLQFMFDYIMPSHPDAAPLMRKLSDNKVDPSVIPRSGPAPVLIRYTDLAGVVPEWERVTAAIEADPVAVKVLDWVREMYAWDVALALRNVTLTTESPPHSHLIAQPPHDLVIGDAAMLHYTWGTLYFEGKTEIWRWEKRDYTSRDVALKVPMLKEPPQPWKEGWRIQDGLPVTRDLHETMTKMLKQMNAAIATLPDLRNRPHA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WTL1</accession>
    <name>A0A835WTL1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Apple domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_002759</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452521.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="536369at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003609">
        <property type="entry name" value="Pan_app"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013122">
        <property type="entry name" value="PKD1_2_channel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23202:SF119">
        <property type="entry name" value="TWENTY-FOUR, ISOFORM B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23202">
        <property type="entry name" value="WASP INTERACTING PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14295">
        <property type="entry name" value="PAN_4"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08016">
        <property type="entry name" value="PKD_channel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50948">
        <property type="entry name" value="PAN"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4 6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 6" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3 6" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="4594"/>
            <end position="4615"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="4685"/>
            <end position="4708"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="4793"/>
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    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
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            <begin position="4835"/>
            <end position="4858"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="4870"/>
            <end position="4891"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="6">
        <location>
            <begin position="4911"/>
            <end position="4933"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="7">
        <location>
            <begin position="2162"/>
            <end position="2235"/>
        </location>
    </feature>
    <feature type="domain" description="Apple" evidence="7">
        <location>
            <begin position="2533"/>
            <end position="2626"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="2900"/>
            <end position="2920"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="3821"/>
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            <begin position="3986"/>
            <end position="4009"/>
        </location>
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    <feature type="region of interest" description="Disordered" evidence="5">
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            <begin position="5563"/>
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        </location>
    </feature>
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            <begin position="5691"/>
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    </feature>
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            <begin position="6192"/>
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    </feature>
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        <location>
            <begin position="6329"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="4223"/>
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        </location>
    </feature>
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        <location>
            <begin position="5108"/>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="5139"/>
            <end position="5148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="5396"/>
            <end position="5409"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="5">
        <location>
            <begin position="5574"/>
            <end position="5588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="5691"/>
            <end position="5709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="5753"/>
            <end position="5767"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="6192"/>
            <end position="6206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="6231"/>
            <end position="6241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="6336"/>
            <end position="6345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="6367"/>
            <end position="6376"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50948"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2452521.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="6376" mass="663328" checksum="D24E5103CF384983" modified="2021-09-29" version="1">[encoded data, 6376 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUP7</accession>
    <name>A0A835WUP7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_000474</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454634.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10602632at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
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        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000980">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
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        <property type="entry name" value="MAPK"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
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        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
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        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
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    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
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            <begin position="1"/>
            <end position="182"/>
        </location>
    </feature>
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        </location>
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    </feature>
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        <source>
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        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
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    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
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    </evidence>
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        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
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        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1409" mass="139587" checksum="CF07A4AAB72F5688" modified="2021-09-29" version="1">MLRALTYLHDHKILHRDIKPANILMDPDTCVAKLCDFGFARWTDCGPRDVQRCTSYVVTRWYRAPEVLVSDEYGPSSDVWSFGCLMAELATRRPLFQGTSTVDQLWRIMRCCGPLTPSQTQLMCSDPRLQTLVGLMPAAPIKPLRTRLPEVEPRLLELVATCLALDPAARPTARELLRLPYFWDLPRYIAGHAQLEAWYREDQGAAAAEAEAAAATTAAAAARLKAAPLPVAAPLPRVAQPPAVDATVTAPAAALPGAVKAAPAVLGGDRLSMHNQANKPPSQQQLQQQPQVSMMMALNQAAAAAARAAKAASLKQEAVAAVAAADVLAAAQLQQEPPAATSQSYAPPAAAAAPVDDPMDVAPVASGCGSGAVVSAEQQLSSSAECGNHQEQHAAKRAQAEASTAVPAELPAPAPAPLEVPAAAISPVTAMPKSFQQLQHVLDCEDDKAAGRGRRQQQPQPQQQGCADGATAAAAAAVSQAVAAGATCAAAASAGSGCAAPSAFSGPGGGDDHQQQQQQSSDGQFLVVDLMGSTGVQTATPTAPTDGVLTGLLVTPGASGSQQPIAMSPMTDSAGGLHGAAAAVTAAAAGAAAAPAGGSGQRIPRRNPSMVLLQTQNSMMLMANEFDSATTPVGAPPPRESQDGPLPHERPGVAALTTTSGAHPQAATVGGSRTRGVRRTVTCIALGNEAQQGMGVNAGAGAGAGAAAGARAAAGGRAHARAVAMDGAAAAAAHGVSRVAARLAAAGGAGVRGATVSGGIAPHAPQAPQLAIMRPARPPQPSLLQQSQPHAQTGPHTFMSLATVHTADAPIVLPPTLMHTRSIAVYPTADGAVAPPAHSHVPGGSMTSLPAGSDTFVGGGGGGRGDMGMLLQHLSYDASAYTPPVGAAGSVSSPMPQQQDVPVGSQPAALVASDRRRRCATQYGMVAVSSGQRAHASASDFDAAAGATSSGSHRSVEGQVQQQTAGGRLFDSSASPRGTHRSLPWRGPSRLSQIGLRLDSPSGAAAAAAGSGEGSTSPPMAVSMGMGLTPTNSGPYPAAAVAVTTPSNHSAWMALSGGVVGGSGGGGMTNGGLGAHGFPTTWPAPAALVPVTSSADLNNKPTALSAAELGAASSGAPLARRSSAGASQQACDGAALLPVALTSSGPAVSSPASRLRRRTVTGDVLLVLPLSGDPVDAALVQQGGDGGVQSGQATAGTPRAGAIRGHRSVEASFTTSALGPPGSPRAAVSATAAAAVAVAAAGSGGGISVITRSSATASGLGVLMAAGGGVGSPRVLPMVAVDSVQGSHVPSRSAQAGGGSQKSMAVAAPAAASGNTGLVVVGAGYAGNGAQPQAQQQRRPQELGGQQRSLSSSGNAASAHTDAPATAPTVPPHVTGASSSSSRSSGGGGAGSGTINKLVQAFKRVVSKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WV01</accession>
    <name>A0A835WV01_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_000631</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WV01"/>
    <dbReference type="OrthoDB" id="783096at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016788">
        <property type="term" value="F:hydrolase activity, acting on ester bonds"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440:SF0">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR32440">
        <property type="entry name" value="PHOSPHATASE DCR2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2454798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="168" mass="18171" checksum="7AF3074E7DF33F87" modified="2021-09-29" version="1">MALEKMAGRKVPAVAFTHIPLPEYDSAFVCNLPADATNITIGTMADFGMKSKSGMGKVLANNCSFGSTLGVFHEGVYSANVNGGLFSAMAMRGDVKMFNVGHDHVNDFCTPFYGIQLCYGGGFGYHAYGKAGWPRRARTIDLYGNGTVHTYKTLDSWGAYAEIDHQSF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WV17</accession>
    <name>A0A835WV17_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RBR-type E3 ubiquitin transferase</fullName>
            <ecNumber evidence="4">2.3.2.31</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_001978</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="2">Might act as an E3 ubiquitin-protein ligase, or as part of E3 complex, which accepts ubiquitin from specific E2 ubiquitin-conjugating enzymes and then transfers it to substrates.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[E2 ubiquitin-conjugating enzyme]-S-ubiquitinyl-L-cysteine + [acceptor protein]-L-lysine = [E2 ubiquitin-conjugating enzyme]-L-cysteine + [acceptor protein]-N(6)-ubiquitinyl-L-lysine.</text>
            <dbReference type="EC" id="2.3.2.31"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RBR family. Ariadne subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.3.2.31" evidence="4"/>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453768.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WV17"/>
    <dbReference type="OrthoDB" id="10009520at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0061630">
        <property type="term" value="F:ubiquitin protein ligase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20346">
        <property type="entry name" value="BRcat_RBR_ANKIB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd22583">
        <property type="entry name" value="Rcat_RBR_ARI7-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd23141">
        <property type="entry name" value="RING-HC_ARI6-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.120.1750:FF:000005">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.40.10:FF:000019">
        <property type="entry name" value="RBR-type E3 ubiquitin transferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1750">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045840">
        <property type="entry name" value="Ariadne"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048962">
        <property type="entry name" value="ARIH1-like_UBL"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031127">
        <property type="entry name" value="E3_UB_ligase_RBR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002867">
        <property type="entry name" value="IBR_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044066">
        <property type="entry name" value="TRIAD_supradom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11685">
        <property type="entry name" value="RBR FAMILY RING FINGER AND IBR DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF19422">
        <property type="entry name" value="Ariadne"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01485">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22191">
        <property type="entry name" value="IBR_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21235">
        <property type="entry name" value="UBA_ARI1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13923">
        <property type="entry name" value="zf-C3HC4_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00647">
        <property type="entry name" value="IBR"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51873">
        <property type="entry name" value="TRIAD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="7" id="KW-0677">Repeat</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0833">Ubl conjugation pathway</keyword>
    <keyword evidence="10" id="KW-0862">Zinc</keyword>
    <keyword evidence="8 11" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="14">
        <location>
            <begin position="127"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="RING-type" evidence="13">
        <location>
            <begin position="131"/>
            <end position="177"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="12">
        <location>
            <begin position="25"/>
            <end position="36"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001798"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00003976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00012251"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS51873"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG2453768.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="542" mass="62020" checksum="3D86BE45CED36808" modified="2021-09-29" version="1">MSDSDEEFRSGSEDEEMSDYGASDADMDVEDDDDDYGFAGAEEVSAVPKVPYKVLPKEELTKQREKALREVQDVLGVDEDTAMRLLRKYKWDASRVQEEWFSKYDQVRDSLGLIDEPGPSGRPAAETEERCYICFDSYPVRDMRAAACKHYFCKDCWRGYITQALSSGPACLDLRCPSTECKKKVCVPSSLVMELASGEEQSKYSTYLVRSFVEDNSAMCWCTGKNCENAIQCLVDRGPNEAMDVICSCSATFCFNCKEEAHRPVSCETVTKWLTKNSAESENMNWILANTKPCPKCSRPIEKNQGCMHMTCSQCRFEFCWLCQGDWKEHGERTGGFYACNRFETAKKKGEYDDESRRRENAKASLERYMHYFERFDAHSKAREKARLDASKVSKDWLEQLADITKTPTSQLKFINEAWNQIVECRRMLKWTYAYGYYAFEDADRNTEVARHKGFFEFLQGDAERSLERLHEAAEKDLGAHVTKARNLADGGFDVDAFQTFRKNLIGLTDVTAGFFDKLVKQLEKGFGSMEADYAGEKQVKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WV23</accession>
    <name>A0A835WV23_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="15">Glutathione-disulfide reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_001010</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="8">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
        <text evidence="8">Binds 1 FAD per subunit.</text>
    </comment>
    <comment type="similarity">
        <text evidence="1 10">Belongs to the class-I pyridine nucleotide-disulfide oxidoreductase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2453964.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WV23"/>
    <dbReference type="OrthoDB" id="5956163at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004362">
        <property type="term" value="F:glutathione-disulfide reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0045454">
        <property type="term" value="P:cell redox homeostasis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034599">
        <property type="term" value="P:cellular response to oxidative stress"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006749">
        <property type="term" value="P:glutathione metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.390.30">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.50.50.60">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036188">
        <property type="entry name" value="FAD/NAD-bd_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023753">
        <property type="entry name" value="FAD/NAD-binding_dom"/>
    </dbReference>
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        <property type="entry name" value="FAD/NAD-linked_Rdtase_dimer_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046952">
        <property type="entry name" value="GSHR/TRXR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001100">
        <property type="entry name" value="Pyr_nuc-diS_OxRdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004099">
        <property type="entry name" value="Pyr_nucl-diS_OxRdtase_dimer"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012999">
        <property type="entry name" value="Pyr_OxRdtase_I_AS"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF004776">
        <property type="entry name" value="PRK06116.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR42737:SF9">
        <property type="entry name" value="GLUTATHIONE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07992">
        <property type="entry name" value="Pyr_redox_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02852">
        <property type="entry name" value="Pyr_redox_dim"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF000350">
        <property type="entry name" value="Mercury_reductase_MerA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00368">
        <property type="entry name" value="FADPNR"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00411">
        <property type="entry name" value="PNDRDTASEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51905">
        <property type="entry name" value="FAD/NAD(P)-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55424">
        <property type="entry name" value="FAD/NAD-linked reductases, dimerisation (C-terminal) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00076">
        <property type="entry name" value="PYRIDINE_REDOX_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="3 8 10" id="KW-0274">FAD</keyword>
    <keyword evidence="2 10" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="8" id="KW-0520">NAD</keyword>
    <keyword evidence="8" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="4 10" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6 10" id="KW-0676">Redox-active center</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FAD/NAD(P)-binding" evidence="12">
        <location>
            <begin position="47"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="domain" description="Pyridine nucleotide-disulphide oxidoreductase dimerisation" evidence="11">
        <location>
            <begin position="395"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="7">
        <location>
            <position position="493"/>
        </location>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="102"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="167"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <begin position="226"/>
            <end position="233"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="319"/>
        </location>
        <ligand>
            <name>NAD(+)</name>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="8">
        <location>
            <position position="360"/>
        </location>
        <ligand>
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </ligand>
    </feature>
    <feature type="disulfide bond" description="Redox-active" evidence="9">
        <location>
            <begin position="93"/>
            <end position="98"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007532"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023284"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR000350-4"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF02852"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF07992"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2453964.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="15">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="514" mass="54668" checksum="773DB637C0FC0C3E" modified="2021-09-29" version="1">MNVAMNLAQGLPRHCLKAVRTRSARLQRGLCTRVSASAGAGEQYDFDLFTIGAGSGGVRGSRFASSYGAKVAVCELPFDYISSDTKGGVGGTCVLRGCVPKKLMVYAAEYADDFKASQGFGWTLPAGAATHSWTGFIEAKRKELQRLNGAYKNTLKNAKVELVEGRGRVVDAHTVEVDGKRYRAKNILIAVGGKPHKLDIPGAELCITSDEALELPECPKKVAVLGSGYIAVEFAGIFSRFGAEVHTVYRQPLPLRGFDGEVRKFAAEQYAAAGLHLHHSSNPVSVSKQANGKLSLVVKGPDGATSTLTDLDQVMMATGRVPKTSGLGLEEAGVKMGSKGQVVVDEYCRTNVPSIWAVGDVIDRIQLTPVALMEGMAVAKSVALNTPTVPDYTAVPSAVFSNPEIATVGYSEEQAAEKFGDLDIYTTSFKPMRNTVSGSPLRTFMKVVVDAASQKVVGMHMVGAEAAEIMQGFAVAVKVGVTKQQLDSVVGIHPSAAEEFVTMRTVSRQVRKSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WV28</accession>
    <name>A0A835WV28_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_001288</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454255.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WV28"/>
    <dbReference type="OrthoDB" id="537063at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="241"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="370"/>
            <end position="446"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="43"/>
            <end position="66"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="85"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="118"/>
            <end position="138"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="149"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="251"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="277"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="370"/>
            <end position="381"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="382"/>
            <end position="393"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="435"/>
            <end position="446"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2454255.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="685" mass="68666" checksum="8EDF9AC39837C758" modified="2021-09-29" version="1">MRTTLTALADKQAGMPGGAPSAAGLMDGSSADAATPPTLTPCSSSRSHASDGSSGSGSGCSKSSGSRSGGGEAAGRKVRRGGSVRGAAAWVAAAARAVRTAARAAQTSLRTSMRRRGGSSSSSSSSSRHCVLGAAAGPDAGGAGRHMSQVREEQVREEQGREQGQRQPPSAQEGGEECQHAGPGGADGSVDGQAARGALRPASRTGAAGKTSPAAAEAEAVGRQLLRQLLQQSPSQAVASLAAATGAPQGSSGGGGGGGGSNAGAATATAPTSSPDTTPAPPAPPGPPGPHCGGAACRLGPAAASLLAPLGALPAAVASGAAEPTMIPAYLRPECAHFDAARGLVTAPTAELAAAAAAAGGGQLYGLPTPSAAEALPPEAAEGGGGGGGGGGRRLSRTATRGRSLRRIPPEVLGRGPPTAGAAPDAEEEGEGERQQQPEPAAAAAAAGGRFPLTVTAWHDLDPRRPDNVLTFYGGVGGAVPYIDRSCGQVANGAVAFRQGFGCGARMEGGVLPGWSSRSGSPFTLVWIGRFGADTGEHEQWLLGLGRSKAGYERELFWSSHELFTYNTNTGFAMKHAFSEGRRPPSGEWTFEALVRYPGATSAAFFRRSQSSRLARWPLFCHPRSVSGDSLSLGADWRDWGNAPWNPKCLSGGAVAVVLVYNRALSGADLQLLSSYYAPRFGFQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WV38</accession>
    <name>A0A835WV38_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_000416</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454572.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WV38"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12413">
        <property type="entry name" value="RRM1_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12414">
        <property type="entry name" value="RRM2_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12416">
        <property type="entry name" value="RRM4_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001727">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000182">
        <property type="entry name" value="RNA-binding motif protein 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="15"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="303"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="591"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="748"/>
            <end position="845"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="250"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="392"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="860"/>
            <end position="1153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="408"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="425"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="535"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="565"/>
            <end position="578"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="579"/>
            <end position="590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="860"/>
            <end position="875"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="902"/>
            <end position="920"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="921"/>
            <end position="957"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="958"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="973"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1010"/>
            <end position="1020"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1021"/>
            <end position="1031"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1052"/>
            <end position="1062"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1087"/>
            <end position="1117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1121"/>
            <end position="1140"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2454572.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1187" mass="126536" checksum="A5B668F7D741F538" modified="2021-09-29" version="1">MPAAKSAEDAEKDLRTVFVRGVSFDAVEKDLEAAFSDVGPVKQCFLVRVKGQPKHRGFGFVQYALPEDAERAVGELDGKSLKGRKLQVELANKRAPLEERKKKRKGAAEEDAPAAEATADADGAVAADADDADAVLAKQPAGKQAAPAAPAPATKRPRAATDAAATSEKHKLLRAVAVGNLTPPAISQAVALARKVGAVEEVMNPAPPEVLREAKLEADGCTGAVVVVVYKTVKDAMTAVSKLHSQVITLAPPGQQQGGKKKGKGKKGGDADADEEAAGGEAAQHITLWAREVKGEGAHVKQWRVILRNLPFKITEAALQKALSPVGFVWELKVPRSPDGRVKGFAFAAFTCRAHAEKAISTLNGRELMGRTIVVDWAVSKAQYEAAAKATAKEAGKETGEAGQDKGDGDDDDDDNDDPDRPESGSEEGEDDEEQGDDDAEEEDEDSEEEIGMDSDDNDGDILDDDEEEEDEEDDDEEDGEEDEDAQDDEDEEQEEDDDDAGQDADARRERGLLSSVLQDVLKEHEGEQQQADGKGTKDRDGKQPQQKQDAKAAKPAAKPTWQGEESHDPDAAAERSRPGSTSNPTSSLETTVFVRGLPLDVTQPQLQSRLELFGPVKSCRLVMDKASGKPKGTAFVEFREAEAASKAAEACARGRRNEGPGITLAGRPLDVDLALSGDGARSLATQRQAGKAVGKDRRNLYLAKEGAITEGSPAWNAMSPHDQAKRKRAAEEKNVKLKSPNFVISRTRLSVRNIPPGWTEAKLKRLFVDAVKERATKENPRVVQAKILKEENRYEASGARKSKGLGFVEFESHEHALTALRQLNNNPGTSFGRERRPIVEFAIDNVKVLKKIEHLREKAKQNAERQAKAKEERQAAAGEANGDKPGKKQRGKKAKGGEGDAGQNAEAEAAGGEDAATDGPKSKRDKRQERKDKKKKEAKEEKGGKEEKGQKRKAADGDADEDDEGDGGMTSRQRKRQRQKERVAHKKQLLKEGGVPALVAEVEAKRAQRAQGGAAAADGPKGKQQQDGRRAQNGGKADAEGLAGVARRKRQAEEQELDRIAEQGLNSKGPRGNGGAQQGGKRRRRSEMGEEGDGRADKLDRLVEQYKVKLSGEKPKQQAGGKGGQGGKGGQGGKGGQGGKGRKGGKGAAVGGTTATKIGGGGAAATAGGVAALVSGAASGMRRWFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVR0</accession>
    <name>A0A835WVR0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_001109</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454068.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVR0"/>
    <dbReference type="OrthoDB" id="202415at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032514919" description="Glycosyl transferase CAP10 domain-containing protein" evidence="4">
        <location>
            <begin position="22"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="5">
        <location>
            <begin position="178"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="25"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="46"/>
            <end position="67"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2454068.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="498" mass="55624" checksum="E2335825BC6A9C2C" modified="2021-09-29" version="1">MLGVPLLALVALLLCAHACAAAAPSKESTSSPRRGDAVAGVAVRRSVRDSGGDEGDGRGDDNVDDHGSTQYPPGGADRGFPSYEEAEGYMKLKCKNYEVTYEQIEHDLAIHRQLGTHYNSTRYAIKWLHRRNGMPIGFFGGRAYLLMKPDWKNLAHHAKLHVAYMRMMVHLEETFGRAIPDVVLVVSSADIPRYVSPRLVNVSSPEPQLPPTRDSGSGSKTLAGFVPGPYPVAGICKSDFWPDMLLIPNFHFHMKLYDSVSLAPIHEFRKKHPWATREPVLFGRFSHYNLMREAGDASTYKLGQKGEDICTNGNATCMGREHFVTRVAKQDSERLDVKFAGMQPMAGHARFKYLINLNGQSISSRLEQLLPLGSLVFTEASGYYAYYYRTLLKHRVNVLEFWRRWPEEVFEELDWAQAHDEEAEAVAAEGARTAATFLTGAGRTCYWFRLLHGLAHTLRFEPRLVKWPGAKLVREVLEQGLQHAPGGQDLAAASSWAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVS6</accession>
    <name>A0A835WVS6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_000416</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454571.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVS6"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd12413">
        <property type="entry name" value="RRM1_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12414">
        <property type="entry name" value="RRM2_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12416">
        <property type="entry name" value="RRM4_RBM28_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001727">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000182">
        <property type="entry name" value="RNA-binding motif protein 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051945">
        <property type="entry name" value="RRM_MRD1_RNA_proc_ribogen"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039">
        <property type="entry name" value="RNA-BINDING MOTIF PROTEIN 14B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48039:SF5">
        <property type="entry name" value="RNA-BINDING PROTEIN 28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="4"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 5" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="15"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="303"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="583"/>
            <end position="669"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="7">
        <location>
            <begin position="740"/>
            <end position="837"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="92"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="138"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="250"/>
            <end position="279"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="392"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="852"/>
            <end position="1145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="114"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="392"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="408"/>
            <end position="418"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="425"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="527"/>
            <end position="545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="557"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="571"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="852"/>
            <end position="867"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="894"/>
            <end position="912"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="913"/>
            <end position="949"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="950"/>
            <end position="959"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="965"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="1002"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1013"/>
            <end position="1023"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1044"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1079"/>
            <end position="1109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="6">
        <location>
            <begin position="1113"/>
            <end position="1132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2454571.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1179" mass="125662" checksum="5F9ED57978BEC626" modified="2021-09-29" version="1">MPAAKSAEDAEKDLRTVFVRGVSFDAVEKDLEAAFSDVGPVKQCFLVRVKGQPKHRGFGFVQYALPEDAERAVGELDGKSLKGRKLQVELANKRAPLEERKKKRKGAAEEDAPAAEATADADGAVAADADDADAVLAKQPAGKQAAPAAPAPATKRPRAATDAAATSEKHKLLRAVAVGNLTPPAISQAVALARKVGAVEEVMNPAPPEVLREAKLEADGCTGAVVVVVYKTVKDAMTAVSKLHSQVITLAPPGQQQGGKKKGKGKKGGDADADEEAAGGEAAQHITLWAREVKGEGAHVKQWRVILRNLPFKITEAALQKALSPVGFVWELKVPRSPDGRVKGFAFAAFTCRAHAEKAISTLNGRELMGRTIVVDWAVSKAQYEAAAKATAKEAGKETGEAGQDKGDGDDDDDDNDDPDRPESGSEEGEDDEEQGDDDAEEEDEDSEEEIGMDSDDNDGDILDDDEEEEDEEDDDEEDDDEDEEQEEDDDDAGQDADARRERGLLSSVLQDVLKEHEGEQQQADGKGTKDRDGKQPQQKQDAKAAKPAAKPTWQGEESHDPDAAAERSRPGSTSNPTSSLETTVFVRGLPLDVTQPQLQSRLELFGPVKSCRLVMDKASGKPKGTAFVEFREAEAASKAAEACARGRRNEGPGITLAGRPLDVDLALSGDGARSLATQRQAGKAVGKDRRNLYLAKEGAITEGSPAWNAMSPHDQAKRKRAAEEKNVKLKSPNFVISRTRLSVRNIPPGWTEAKLKRLFVDAVKERATKENPRVVQAKILKEENRYEASGARKSKGLGFVEFESHEHALTALRQLNNNPGTSFGRERRPIVEFAIDNVKVLKKIEHLREKAKQNAERQAKAKEERQAAAGEANGDKPGKKQRGKKAKGGEGDAGQNAEAEAAGGEDAATDGPKSKRDKRQERKDKKKKEAKEEKGGKEEKGQKRKAADGDADEDDEGDGGMTSRQRKRQRQKERVAHKKQLLKEGGVPALVAEVEAKRAQRAQGGAAAADGPKGKQQQDGRRAQNGGKADAEGLAGVARRKRQAEEQELDRIAEQGLNSKGPRGNGGAQQGGKRRRRSEMGEEGDGRADKLDRLVEQYKVKLSGEKPKQQAGGKGGQGGKGGQGGKGGQGGKGRKGGKGAAVGGTTATKIGGGGAAATAGGVAALVSGAASGMRRWFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WW34</accession>
    <name>A0A835WW34_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">HTH myb-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_001933</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453721.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WW34"/>
    <dbReference type="OrthoDB" id="552649at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="27"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="290"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="507"/>
            <end position="612"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="48"/>
            <end position="62"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="77"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="341"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="368"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="513"/>
            <end position="525"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="526"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="612"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2453721.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="896" mass="86496" checksum="CFF968AA19888021" modified="2021-09-29" version="1">MGALGGKLKTAVQIRSHAQKYFNKLEKAGDAAEIQVPPPRPKRKSVTAAQRAAAAAAAAEQQLNPRSGSEERGYGEPQDDNDGGSDGGAEDGEPGYGQHDRLGSPEDLPLTAELQGMQLQPPRSGAAAAGALGPLAAAAGLPQLPVLQQQQQQQSAVVQQQLAQLQELQQMQLQPFAAPGLMPFHATASAAAAQLPVLAAAAAAGQAGGSVSGGAGSVPLGLAGLAPATAVAMAAATAAAVLPPSGGGLPQASPFTTLQGPLALPATLGGSTPSQLLAAATAGALALPSSPSPPPLLGPGLPAVGVGALGQQQQQTQQQQQAQMQTHQQTQPTPSGTTLSAQAQLQMQASPQQQQQHQATPLESASFGAGGGGPGVGPGGFSLADSIARNIAINMAQWAQAQVQVPDAAPAPASAPDRQTVEAVAAAAAAAAAAAATAVISAAGEAIQQRIQEKAAAGFLPFLVHPLAELIPPSLAARSGSAATTSEQSAPPWALPQQQQSLLHVLGGSASTGRGGGSAGGGAGGPQPQSAVGAPPVRLQQQSSQQRQQLSPPFGLGTGAAGAEQQLTGTRDDTHTGQHTGGTGGTVTPGSSAQQQGGAVSGPASNSPQHMSPSFAAAAAAGAGTGGGAGGGGASVSMAGGLGGLPSSSLVASLGGGASISLGGAAAMSLGVDLQPPPQLLAAAAASPVPMDWDVAAAVARASQLQQQRQTAPGLGLIAPQPAALQSSASAGLLRTLSLPAAWEGTAAAQAAAALQSREVLSRLAAAYTSDAPSSAYPQLQVAVVAAAAAAAQPQSQTQTLPELLPSRLSVEQVQAPVSLPGGGGTSSAFQVLRPSTSQQLLQQQYQLDGAGAAAAAAAAAAAVAARGPGAAAVAAAAPAAAAAAGAAHQGGGADG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WW55</accession>
    <name>A0A835WW55_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_000961</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2455142.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WW55"/>
    <dbReference type="OrthoDB" id="562450at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030149">
        <property type="term" value="P:sphingolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393:SF6">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="264"/>
            <end position="359"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="476"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="698"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="275"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="484"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="706"/>
            <end position="721"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2455142.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="826" mass="89939" checksum="D63AA4EF7827D788" modified="2021-09-29" version="1">MHVQELRGNKEGNVWSSLSGTPEIIRLIAARLPRNEAARCFRLLSRDVAESLKGSHDVIYVPKERASLGYFSDDVYIATQPWFGVDFVARFARPEPWRSLSYAVRLRLLCLAASSHHAPSLDAALAFSGVGLTSTAIVEAAAASGDLDACRRLVAAGCECSFRAVELAAFRGRLPVLQWIWWEPNPAFSEEKRQRLEQEQRDWDRMDRQARAMEARTPPPPPPPATLRRAFGWADTAYVAFAACAGGQGEVLTWLERGMWRRAGEAPNEQEEAEQPQAQQQPQPAGEVAAGAAAGGLELQEADKEAAAEEQDGDEEVEEDSDGSEDPDPDPDQATEKPLPTQQEVAAARAGRFAPPTGFKRSWLERQAMAREAASRGHTALLRRLLLPPGVVEYGRLPRDRHFSEIDFAVVTHATYGCPLEELQALFGAWEPGQRGVPGGRDGAVWLLRAATSPTPDWRAKADYVCEKLRLRVEGRAGTKPSSEEDVEEGDNGDDGGPAWVRVRELLQYGFEGVPFDRTDWEAVAASPDLLARWRYLASCGLPYGWRAWAAEVAAAGGNVAALTELLDARARAVANGDAAAEMEPAEAAARAAWLWHRQREADRMQQQYQAMHDQVLLELAADVQQRIHEERRRQPPDFVGPAAEAAARAGQVAVLSLLRDRCGPGVLKLEHAGLASRHGHVEAVGFLAEALEPVPRPAPAQAAGSWGGGGLQGQGQGRGRGAGEAAAMQAYTEAVLVWTRAWSLMAKAGAGVALLQLLRERHGASPDLEAVAEGGSVEATEWAFEQLRAEMEPGAVFFHRHLASSLQCRGNMATAAWFRERGLSM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WW56</accession>
    <name>A0A835WW56_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_000381</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454534.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WW56"/>
    <dbReference type="OrthoDB" id="541358at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="172"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="310"/>
            <end position="335"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="322"/>
            <end position="334"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2454534.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="434" mass="45657" checksum="35C87B970F27D5B1" modified="2021-09-29" version="1">MSLTPELITQFGLLGKVRTGQPLLDALLCLLLPLVLRWAQPRLNRLSLQATATLRQWLTGKAGRKEVVRVIEHVAYEDGYYYDPDGQPANAVLQQALLSYINNCTTSLDAAVASSHSPLAISAPTGPGAARTCARTCARSCTCACACSSPMKALQDMGTAYLSLERRRRRLAAPGDDAASDSDDEGSGERSGSGKSSSGGGGSVSSAGRLREAAAYGLNLAPPVRVWQDLGNGVEFMRYTYVHSSSGSSTYKRRRIGHVVKLRSFGTDGPARVAGLITAALQDHRAQKAARPADRHRYLYVPTCLDPPAISPAPGEPSAGADGRGGGGGGGGGKAAAPQVAAVFKRYRLSSEKTFASLFHPAKDELLRLVAQFEGRQGRFAVPGYPQKLGLLLYGPPGTGARAFEGGDSCARLSAVTWGLGGRPGPRGRYGSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WX79</accession>
    <name>A0A835WX79_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Stress-associated endoplasmic reticulum protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_000907</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endoplasmic reticulum membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the RAMP4 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2455087.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WX79"/>
    <dbReference type="OrthoDB" id="16679at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005789">
        <property type="term" value="C:endoplasmic reticulum membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030968">
        <property type="term" value="P:endoplasmic reticulum unfolded protein response"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010580">
        <property type="entry name" value="ER_stress-assoc"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15601:SF0">
        <property type="entry name" value="GEO09675P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15601">
        <property type="entry name" value="STRESS ASSOCIATED ENDOPLASMIC RETICULUM PROTEIN SERP1/RAMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF06624">
        <property type="entry name" value="RAMP4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0256">Endoplasmic reticulum</keyword>
    <keyword evidence="6 7" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 7" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 7" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="7">
        <location>
            <begin position="40"/>
            <end position="58"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004389"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005500"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022824"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2455087.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="10">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="69" mass="7470" checksum="24B0DA4733849C9E" modified="2021-09-29" version="1">MTVSKRVANAKSGKFHKGVHKRGLVDEAKQKASKLPVGPLMLGFFIFVVIGSAILQIIRTATNPRELPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WYV3</accession>
    <name>A0A835WYV3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">ornithine decarboxylase</fullName>
            <ecNumber evidence="6">4.1.1.17</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_000893</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-ornithine + H(+) = putrescine + CO2</text>
            <dbReference type="Rhea" id="RHEA:22964"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:16526"/>
            <dbReference type="ChEBI" id="CHEBI:46911"/>
            <dbReference type="ChEBI" id="CHEBI:326268"/>
            <dbReference type="EC" id="4.1.1.17"/>
        </reaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1 9">
            <name>pyridoxal 5'-phosphate</name>
            <dbReference type="ChEBI" id="CHEBI:597326"/>
        </cofactor>
    </comment>
    <comment type="pathway">
        <text evidence="5">Amine and polyamine biosynthesis; putrescine biosynthesis via L-ornithine pathway; putrescine from L-ornithine: step 1/1.</text>
    </comment>
    <comment type="subunit">
        <text evidence="7">Homodimer. Only the dimer is catalytically active, as the active sites are constructed of residues from both monomers.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 10">Belongs to the Orn/Lys/Arg decarboxylase class-II family.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="4.1.1.17" evidence="6"/>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2455071.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WYV3"/>
    <dbReference type="OrthoDB" id="5034579at2759"/>
    <dbReference type="UniPathway" id="UPA00535">
        <property type="reaction ID" value="UER00288"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004586">
        <property type="term" value="F:ornithine decarboxylase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0033387">
        <property type="term" value="P:putrescine biosynthetic process from arginine, via ornithine"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd00622">
        <property type="entry name" value="PLPDE_III_ODC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.20.20.10:FF:000005">
        <property type="entry name" value="Ornithine decarboxylase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.10">
        <property type="entry name" value="Lyase, Ornithine Decarboxylase, Chain A, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009006">
        <property type="entry name" value="Ala_racemase/Decarboxylase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022643">
        <property type="entry name" value="De-COase2_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022657">
        <property type="entry name" value="De-COase2_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022644">
        <property type="entry name" value="De-COase2_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022653">
        <property type="entry name" value="De-COase2_pyr-phos_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000183">
        <property type="entry name" value="Orn/DAP/Arg_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002433">
        <property type="entry name" value="Orn_de-COase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482">
        <property type="entry name" value="ARGININE/DIAMINOPIMELATE/ORNITHINE DECARBOXYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11482:SF6">
        <property type="entry name" value="ORNITHINE DECARBOXYLASE 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02784">
        <property type="entry name" value="Orn_Arg_deC_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00278">
        <property type="entry name" value="Orn_DAP_Arg_deC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01179">
        <property type="entry name" value="ODADCRBXLASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01182">
        <property type="entry name" value="ORNDCRBXLASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50621">
        <property type="entry name" value="Alanine racemase C-terminal domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00878">
        <property type="entry name" value="ODR_DC_2_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00879">
        <property type="entry name" value="ODR_DC_2_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0456">Lyase</keyword>
    <keyword evidence="3 9" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 N-terminal" evidence="12">
        <location>
            <begin position="1"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="domain" description="Orn/DAP/Arg decarboxylase 2 C-terminal" evidence="11">
        <location>
            <begin position="226"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="9">
        <location>
            <position position="299"/>
        </location>
    </feature>
    <feature type="modified residue" description="N6-(pyridoxal phosphate)lysine" evidence="9">
        <location>
            <position position="11"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008872"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00034115"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00034138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00046672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00049127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRSR" id="PIRSR600183-50"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="RuleBase" id="RU003737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="Pfam" id="PF00278"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="Pfam" id="PF02784"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2455071.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="368" mass="40065" checksum="3832904DDEECCF9B" modified="2021-09-29" version="1">MPRVVPFYAVKCNPEPGILKLLNALGAGFDCASKGELDMMLRMGVSPNRIIFAHPCKRASDIRYAREHNVQYTTFDTVSELHKIAQMNPDFKCVLRIRADDPDARVPLGLKYGAEVSEAGVLLRTAKELGLSVVGVSFHVGSACQNLSTFSGAIENARKVFDEAGTLGFNMELLDIGGGFTGHFDECGNVMFGEIANTINAALATNFPPEMGVRVIAEPGRYFAETSSTLLTPVYGQRDRTAADGTVKKDYWLTDGLYGSFNCILYDGQNPAYKVVRSPLMSESTDSRTFLSTLWGPTCDSADCVYKDVSLPVLRNGDWLMWNNAGAYTVAGACDFNGIEFTTPGKLYVWSDSAVDAEEAADEQVMNA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B0K1</accession>
    <name>A0A836B0K1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_009066</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000029">
        <property type="protein sequence ID" value="KAG2444126.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="551765at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.190.10:FF:000640">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050697">
        <property type="entry name" value="Adenylyl/Guanylyl_Cyclase_3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="649"/>
            <end position="671"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="3">
        <location>
            <begin position="697"/>
            <end position="751"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="532"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1033"/>
            <end position="1068"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1086"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1289"/>
            <end position="1314"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1347"/>
            <end position="1406"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1516"/>
            <end position="1551"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1570"/>
            <end position="1604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1686"/>
            <end position="1714"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1747"/>
            <end position="1815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1840"/>
            <end position="1947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1960"/>
            <end position="1989"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2093"/>
            <end position="2121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2142"/>
            <end position="2173"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2199"/>
            <end position="2288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2338"/>
            <end position="2357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2402"/>
            <end position="2425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2440"/>
            <end position="2492"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2860"/>
            <end position="2888"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2980"/>
            <end position="3004"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3320"/>
            <end position="3388"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3465"/>
            <end position="3485"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3597"/>
            <end position="3641"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3776"/>
            <end position="3862"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3875"/>
            <end position="3947"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="3977"/>
            <end position="4045"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="4091"/>
            <end position="4122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1048"/>
            <end position="1064"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1123"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1302"/>
            <end position="1312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1369"/>
            <end position="1394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1530"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1571"/>
            <end position="1590"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1750"/>
            <end position="1759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1911"/>
            <end position="1923"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1925"/>
            <end position="1935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1964"/>
            <end position="1977"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2096"/>
            <end position="2121"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2157"/>
            <end position="2173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="2259"/>
            <end position="2270"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="2272"/>
            <end position="2281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2872"/>
            <end position="2887"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="2980"/>
            <end position="2997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="3776"/>
            <end position="3788"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3789"/>
            <end position="3806"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3837"/>
            <end position="3856"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="3924"/>
            <end position="3947"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="4028"/>
            <end position="4044"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2444126.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="4122" mass="408991" checksum="915D528968E5DD89" modified="2021-09-29" version="1">[encoded data, 4122 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3S1</accession>
    <name>A0A836B3S1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008328</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutA family.</text>
    </comment>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446767.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3S1"/>
    <dbReference type="OrthoDB" id="2017693at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010038">
        <property type="term" value="P:response to metal ion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004323">
        <property type="entry name" value="Ion_tolerance_CutA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011322">
        <property type="entry name" value="N-reg_PII-like_a/b"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015867">
        <property type="entry name" value="N-reg_PII/ATP_PRibTrfase_C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419">
        <property type="entry name" value="DIVALENT CATION TOLERANCE CUTA-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23419:SF8">
        <property type="entry name" value="FI09726P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03091">
        <property type="entry name" value="CutA1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54913">
        <property type="entry name" value="GlnB-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010169"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2446767.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="187" mass="19164" checksum="9C4515BF609B9E39" modified="2021-09-29" version="1">MPSVIFALQPRFFGTLALVALLCASSFAWYFSLSGPAIGASGGGGALVRQVAAMSTPAGAAAAAGGSSPTGAIVVYVTVPSAEVGEALAGKLVEAKLAACVNILPGLTSVYFWDGKVNKDPELLLIIKSREELLGELTSFVRANHPYDEPEVIGLPILGGSPSYLQWLMDNTDRKAAAAAAAAAEKQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3S4</accession>
    <name>A0A836B3S4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_008000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
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            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000024">
        <property type="protein sequence ID" value="KAG2446840.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3S4"/>
    <dbReference type="OrthoDB" id="537362at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2446840.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="313" mass="35024" checksum="113882A6D676F40F" modified="2021-09-29" version="1">MRETWLEFAAQQQRARKPKSFSKASSTDVDALLHCAQLQHVRGEALAPQDVQIPAGTPECDSFVWEQGGGENAMTPELLKYHQTQLEKFGVEFDKLGGFEMHDTHSKGKLIPFNCGGRYFSGGFDGCVAPYGLNQESVVFQSRIIYEHKCREMTTTDKQQAIVELLGAYAYNSCPVLLDLTNGRTHNIYTIRGTCVYVWKDLKPTQAYILQARHLQAADRLRAALDLQLGQIPEEEQRTMRHVQQALAPVIGGAAALQEQLDSLLPFMAPEERELVSQDLVRSWAQGADFTQPPEEQIQIPALSLPATPSFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4P1</accession>
    <name>A0A836B4P1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_007428</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447502.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4P1"/>
    <dbReference type="OrthoDB" id="553174at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="617"/>
            <end position="641"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="653"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="472"/>
            <end position="496"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="516"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="16"/>
            <end position="35"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="36"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="50"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="61"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="90"/>
            <end position="104"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="339"/>
            <end position="350"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="351"/>
            <end position="365"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="472"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="516"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="551"/>
            <end position="564"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2447502.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="697" mass="65035" checksum="F4744BC5F59B40DE" modified="2021-09-29" version="1">MDPRATHGAHTGCCYRTTATTGSSNAGTGSSSSSSGGSGSSSSGGRGSRLRVAAASSSAAGAGGALGKEGGVGAGGGEGPGAAAAAAAEDEARPGEEQAEAREAFEEDRELLLHCPDALINAAAGLSPAAATAVFAPTGGGGGGGAVIGPSSSSASSSLGLLAAAAATAASSAAASPHLLAPLSLSPGTIAAAALAADAGSNRRRRQAGGWLYGAGTDEFRGYITVGVDPADVENTDPAAGSYEEADGSFHGFSRTLGVMADEPAGPAAGQSVAAAAAGAGPSASSSWPAAVAEAAAAVAAALGTGGAGGSAGSSSSAAGGWAAGGFKGGGGWRGGEAAGHAHAAGYDTPQMPPSTPPSQPPMLPMPERASRPIAIPLPHPGGPGAASTAAGMMAGDWRAAGATGASGADEELPSAAAADGAVGATAAAARRPGAGSSSSAASAHSAPVQGALTNAAATAAGVDAAASRASVDGYRGGSSSRGCGGGSSSSGGRVRRVTFAPEVGREELQQLVAAAPQSGGAAAGAPAAPRVPPSARPGSSSSRGRGGGSSNAAADTTSTSSSSFCSDDAAAALAAVPYTRLVDRDEAAVLAGSSTAAAAGAGEGGSSNRRGSMRHAALKAGAAARGALVLLPLTGALAWVSARLLLSPDRTAVALAGLGCLLTAASASLATYLALTAATAASRDPAAAPEYSSSIV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4P3</accession>
    <name>A0A836B4P3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">WW domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_007540</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447621.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4P3"/>
    <dbReference type="OrthoDB" id="547603at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00201">
        <property type="entry name" value="WW"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.20.70.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001202">
        <property type="entry name" value="WW_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036020">
        <property type="entry name" value="WW_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12752:SF9">
        <property type="entry name" value="KRAMER, ISOFORM I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12752">
        <property type="entry name" value="PHOSPHOINOSITOL 3-PHOSPHATE-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81995">
        <property type="entry name" value="beta-sandwich domain of Sec23/24"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51045">
        <property type="entry name" value="WW domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50020">
        <property type="entry name" value="WW_DOMAIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="WW" evidence="2">
        <location>
            <begin position="359"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="100"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="234"/>
            <end position="299"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="585"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="805"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="101"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="127"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="234"/>
            <end position="244"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="245"/>
            <end position="258"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="263"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="585"/>
            <end position="618"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="635"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="661"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="805"/>
            <end position="819"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="820"/>
            <end position="829"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2447621.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="859" mass="89994" checksum="D88B22B9125B607A" modified="2021-09-29" version="1">MVSARGDVARGPGAAPKAVATKLPLGPAASLVLPLATVLAKLGNDPQQLLGWEVRVAAPAGRGLRKLPGSSSGSAPASGQAAGLRARSVLGVVVGVEIQHHQSSNTNSARRTLEQQEAHSTHYPSNQQQQQPLGQRPAKQQQQQQQQQQEPQAVLRVVRRATLDTCGGFEGEQELLLPLEPGVVARGDLVGRALWLDAVPSDLLTAARRGLLLQLIRRELLRLHDAAAAGPLLPGASAAPLAQHHPQHPPDHHHRHQQHPPDQRQQQQQQQCQQQRQQQRQQQQQPRTREAEQAVLARMPMPSRQELLAGDRAELVEAITAAGGFAEVALQLGLRCSRRPHGFWSGPGSWRRLAEELAAFVAAAWTELPAPDEPGRVYYYNQVSGRTTWRRPAAMSAAPSWVAGGAPGAAESATVAAAGGAAGRGGSSRGVGAKGVLEAEAAADKVMPSRAVIMKAKRRDLHGAVMMHGGYEAVAAALGRRVTWALSRRLVGGPPEQLRRELEAAAEELGLPAGVMPTARELQDAGHGALLTAVRQSGGFQVVARQLRFTPRGKRRPRGSWEDPKRLAAELAAFAAATAAAAASSKGAVGDGSSSSNSSSSSSSSNSSSSSNSSSSSSHAVDPGTEPQRAPGQDAVAEAGARAPAAAGEPDTQQQHHHGHEHPEQQEHEQQQQQQRRGELLLPFPTRSQLLAAGRQDLVAALQNHYHGADRRALLAQLGGLQLTSRRGTNRNALSLELVVAAIQAGHHTPQSIRAYLAAEAGVEVSQQYLGQYLRRNSSRAAPDAVAPAPATSLAHAAVASVTAGAGAGPAGKRSAATPGGEGGGGGRGADAEAGGSADALLVRRGHGRYELAPGLDRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4U5</accession>
    <name>A0A836B4U5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Golgi SNAP receptor complex member 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_007201</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of several multiprotein Golgi SNARE complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the GOSR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000020">
        <property type="protein sequence ID" value="KAG2447741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4U5"/>
    <dbReference type="OrthoDB" id="422156at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048219">
        <property type="term" value="P:inter-Golgi cisterna vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023601">
        <property type="entry name" value="Golgi_SNAP_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094:SF2">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094">
        <property type="entry name" value="GOS-28 SNARE- RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027109">
        <property type="entry name" value="Golgi_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="220"/>
            <end position="239"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR027109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2447741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="240" mass="26093" checksum="BD2D71E7D8C84781" modified="2021-09-29" version="1">MAYRSPAPARPPGQTRVWEDLRKEARRLEGELDVKLAAFTKLCSSFEASYKLNTADNSLGADQLAQTKAAEVEDLLQRLSDINDEMAAIVGGSTDSRSHTLARHRDILQEFTQEFRKVNATLGAALDRVKLLAGASDSPHLSVNVQNTSGALLRERGTIQNSANMVDDILSQAANVSGNLLGQRRVFEGAMDKLVQVGSRFPVVNGLLNAIRRKKSKDTLVLAGVIAACVLFTILYVMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B633</accession>
    <name>A0A836B633_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_006044</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000016">
        <property type="protein sequence ID" value="KAG2448687.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="550242at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="17"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="138"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="285"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="407"/>
            <end position="432"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="586"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="636"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="731"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="863"/>
            <end position="935"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="17"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="46"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="142"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="298"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="602"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="637"/>
            <end position="658"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="737"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="888"/>
            <end position="903"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2448687.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1350" mass="131348" checksum="0C8F2C898688FC48" modified="2021-09-29" version="1">MVASGSGEYLQDLATQTASGGASAGAGAAQRAGMRVAPASGSFSGAADTAQDAAPPASQPATSNAGANKPDDTSVLADTSAVGKAGAASAPPAAEPTSPAAAAAKRAAAGVAAAPDAHLAPPLLPAAASTRRGRLPPLEVQGSEAESASGSEDVSPPAPRLSARASTLPAAATATAAAVAAGVRVRSAEEGAKRGSSQEATAAAPAMLNMTTSSLAVASEADAKGAAVASLHRPEDLLISPRFGSGAHSDCLFTMATGASRASEVAWIAGGFEGVDVDCASQPASQAPFLQPRPPAVPGAGARPSPSQPSQQQHIMPCRAGWSLDGRSSLRKLPSGYAGATASTGGGGGGAPPLASAHGMSCVLGNASNSGMPPSTFARATVGPSTSARASGILQLRQSMSGLCPVNEDQQHLHPLDTPMGTGGGGSSSTRLPPLLLATAMRSSARGSAAADAVASMLSGDLGSLGGSGSVGGSSNSCAPSASHLPWVLTPSGAPVLLGGGHHRRLPHQRPPPLVEPYVPPALGTYDSCAFPSGTLSGLLSGPLLSGVLPSGIFSTSGGADNGPGSFGLGPSLGSLHTYSPSAFHGRSSIPGSRGPVTPRGAGAGAGGAGGSGPGIGTRYVTQVAHLNSLADRMAVAQQSSASGGANSGPNSLLGLGQRPAPQTLSGPMTHWPVADGCVLEDSGVLLDCNSHHMRDGSPHAAALDPATIEHAAANAAAANYLATRRGSLHGAVGPHSSGNHAGSGPNNIGKYQTGSGPNSFGRHSVSGTPAVAGLAPGGSPADSQQLIFRVHSVHSAAAVGSNVAGASSGGVGGISASASVTGDYADQPSPFLLGMHSAGVSGAGSGSTHAAPNFSRMSSSNLEMQRSAGSGGMGSVGLLAPQPPSQPQQQSSSRFTRQSTTSVASSNHSVCSLRRGPSRLGQAPGSTAGGMNPSLRFALTRTTSHGLSSNTASASGLDGGDALTSVAVLLHTRSSYNCATYCSASMDGSGAAAGGSVGAVAGAAASGSGMVSGTMSDCGGVEGVGAPSPELDLQQGQRSAPIRGRALKIGGSPDPYDVMELMLTDPLADPRKAAATAAVAAAAEAAVTSMAADAAAAAARRAHAYSAAGMWPAEDRSAVATQSSPRAGAGWATFVAEADAQAQPEGLNHVLVSIDEMAGSATTLVRVGELGMARRPTSLANMHAASPILLGGLMPGDDGTPAPIPAGSGHSSIAMHGGGDIDRACNSRRSVVSIASAVLATPYSFTLQPPGVAGGAQGATTGSEVSGAAAGANDEAALVGPSGDADSGAYAPLSGLYTTSRLSMGAATAEDEAVAAAAKRRASSSGVNTFSRLASGFRKKVEKLKKVLS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B761</accession>
    <name>A0A836B761_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005460</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449304.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B761"/>
    <dbReference type="OrthoDB" id="546939at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="24"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="173"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="222"/>
            <end position="241"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="288"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="354"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="109"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="363"/>
            <end position="373"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="385"/>
            <end position="394"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="395"/>
            <end position="414"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449304.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="422" mass="42203" checksum="8DDB2B6DEB99C57A" modified="2021-09-29" version="1">MEDAVELAERLLLVDFSADYQAPRSVQPAAAAGQSRPGSRSVTPPRAAVQAARDLCQRIGDAATSKKAVSGPAPSHLVSLKLPTQLAAPQQQPQHQLQPNVTQTPTRCGSMTARDRYGSQAAAVALSPVRPAGQLLAAAPAASPGFMTARGPRTSSGGGAHQLGMRTSLDTALPLQQPSPARPAQQQQQQPARSQARSSSHIPYGAAAAAANMLAQAIGAAKPAKPAGTPPRAPYGSAKPAAAADASGADVPSLLLSRLSGQQPGQASTGGGSGGVVTVIGGALGSPLSPSRSAAAQTGSPLTSRQRGSSVTASSITLAPHSSGALTARSPRTPSLLGLQAAVAVAGVTLPAEQPPLSARPRHPAEAEADAAKGGKLSLQLQLPPREEVSKELGGKQQQQPPAGGAGPRGIVPGLRLGSIAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B7V3</accession>
    <name>A0A836B7V3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">GPI inositol-deacylase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_004786</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450277.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B7V3"/>
    <dbReference type="OrthoDB" id="348976at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909">
        <property type="entry name" value="ALPHA/BETA-HYDROLASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47909:SF2">
        <property type="entry name" value="GPI INOSITOL-DEACYLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="192"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="204"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2450277.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="314" mass="32461" checksum="0CC82B5D1B5D4761" modified="2021-09-29" version="1">MARASASVDGSKPSPRRGVLLLPGLGNNAGDYGPLAAQLEARGLAVEVAQVTRPDWGRNAAALTDINWWRGTLKPRPAVNWYLDYVDGAMQRLKRRLEQEAPGAPITMLTHSAGGWLGRVYLLDWGTAGVDRFVSLGSPHCPPPAGAAGVVDQTRGILNYVNDACPGAFHSELTYVTICGKFVRGVPLAGPGSSSSSSSSSSSSSGGGKGAPGGGLRGLLAKFAGAGYQQVCGSPEVWGDFIVPQPAAHLEGALQVDLDGVFHSPLGEKLPFFGPWYGSEQVLERWVHHITGDEAPAGAVEAVAAAAAGSASAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B7Y5</accession>
    <name>A0A836B7Y5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">SET domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_004885</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450381.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B7Y5"/>
    <dbReference type="OrthoDB" id="5945798at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd20071">
        <property type="entry name" value="SET_SMYD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.170.270.10">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053209">
        <property type="entry name" value="Gramillin-biosynth_MTr"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001214">
        <property type="entry name" value="SET_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046341">
        <property type="entry name" value="SET_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019734">
        <property type="entry name" value="TPR_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47643:SF2">
        <property type="entry name" value="TPR DOMAIN PROTEIN (AFU_ORTHOLOGUE AFUA_5G12710)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00028">
        <property type="entry name" value="TPR"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82199">
        <property type="entry name" value="SET domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48452">
        <property type="entry name" value="TPR-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50280">
        <property type="entry name" value="SET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SET" evidence="2">
        <location>
            <begin position="451"/>
            <end position="765"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="583"/>
            <end position="604"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="684"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="8"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="691"/>
            <end position="711"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50280"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2450381.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1100" mass="111937" checksum="AD7504BC326E216D" modified="2021-09-29" version="1">MPLVEQQEQERRRLSAEPREAQPEVAGRCRLCRPRFSGQPLARLTPIRLSQLRVGYVHTGSYVICRTLVTPYKMRAVATVVTDCPEDGEDEGTRLGCQMRLLLHNLPGGRTGGDGTLSAAQPQYGLSAGTVLAVKEPYLAAAGSCPGSGGGVGGGVGGGAAAGVLGTGRSYDAPAATPKPQQRSQPFLRVDSPSDLLVISDPQHPLVAGTAWERHVVAAAAAGAAVRGNCSGASAPQLTSTVATAADAATTDTDEAAHWQAQGNALFGSGHFVDALHAYQQGLAAAGHQQQQQGQAQPQSQSLSEAELATALLNSSAAACLGFGAYESARAYASLALRRAPGDAAALLHLARALDGLGRYSEAAAACEAHIAAAAAAAAAAAAAAAAGVSEATGSSGIAATAGKDTAQRFLAELRRRAAQAERGEYDEAALAREAAASSTPRLEGHADFIGPVAVADAGEGRGRGLVTTVPVRAGQLLLAMRADVASFASDVDVPANVCRDARSASDVAVLGAASAQLKWDLPSAVLGCPRLAARLAHLHAGGQAKVPPLPSATECGFVPTWRPAAGTGADAGADAGAAQGAPGAAALAVQEGGSDSPDGSNVDDAEAAARAFELAVRGPGAVAQSSQRCAFQLGLLKEAPKAAAGHRRRHHHLVRVDMERLSRLCVANGFAFTQLVLRQEQQQQQQQSQGGNGADAGGVGASSSGAGKGDGGFGKPAATGLWGLASYFNHACVANATRYFIGDFMFVRAACALPAGSELSITYLSPMLSYEERSAKLLRRGFPCGCELCSEEAEWRRRHPDRAQQVEELLGRMELLCALAPAALHPAGSHDAKLPDSSTCTAAGHAGADQQCGAAGGRDGPAASPAAAPAAVAPIAIARDAQQPYPAERQRQRQRNWAADVCGALEALEAALHGRTWRTALHAPAVRAAKALGACGALRDAAYAQELAFAALLCRNYHHHHHHDAAQQQAAAGAAAGARQTAGSHSTAAAAGGGASEPAGGGVLAAAARVVAAASDDEAGVMTRIDGQGCVLSPEAAVQAAMDVAAVWRQLAAAAAAAQETPEAAMQRERAWDATARGLWSRYFGGDPVLFAARFGGDP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B9Z6</accession>
    <name>A0A836B9Z6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_003243</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452212.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B9Z6"/>
    <dbReference type="OrthoDB" id="10688516at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2452212.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="275" mass="29279" checksum="0B71ED7A1C1E640B" modified="2021-09-29" version="1">MVAAEENVGSLGGSLADVTERLAGVGLAEGVSTCQLEAPAPTGPCPPLPANVLSLIGRHLTLEERLLAGGACKAWRSGLHEAITLLEYQLDDGSCAEARRHTCQGWAALLAAAGAAASPITAIRARVGLSGNLTTSNSVSVLVAGLASHSHLQHLSVLQAPHNSGHTLPARTRAEGGRLRRRARWARPPFTVFPSISSREMHCLCSRLSRLVSLSLRECIFLAGFDSWLHDLRSLQRLELVPTQEAVCQHVRSPDKRGRVRLRTAGGNQGIRRAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BAK7</accession>
    <name>A0A836BAK7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_003254</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452225.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="547273at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037">
        <property type="entry name" value="FORMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13037:SF24">
        <property type="entry name" value="POLYCOMB PROTEIN PCL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0945">Host-virus interaction</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="482"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="524"/>
            <end position="548"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="703"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1354"/>
            <end position="1545"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1623"/>
            <end position="1656"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1755"/>
            <end position="1781"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2111"/>
            <end position="2140"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2528"/>
            <end position="2554"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3013"/>
            <end position="3038"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3379"/>
            <end position="3405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3486"/>
            <end position="3633"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3645"/>
            <end position="3724"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3797"/>
            <end position="3822"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="16"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1357"/>
            <end position="1371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="1385"/>
            <end position="1423"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1450"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1500"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1526"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1632"/>
            <end position="1654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1763"/>
            <end position="1773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="2122"/>
            <end position="2137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="2541"/>
            <end position="2554"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="3388"/>
            <end position="3399"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="3486"/>
            <end position="3496"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="3542"/>
            <end position="3561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3576"/>
            <end position="3588"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3688"/>
            <end position="3715"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022581"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2452225.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="3846" mass="379272" checksum="8A3B761D9924D8FB" modified="2021-09-29" version="1">MRKFKMLQSRDGKSGNAFSSFSSVASGTNRGGSTDMEDGFVIRGVHKGEEMDKQSLQARTPSFAADAPAPVYRHRPRPSHITKETLEAKQRAEVKRTQAANKFRTAAQLARLAAHSKLAGQRGLGTSVANQVVAKKWKEVGNLLKKTAGGVSRIRALVEKDKRSYLAAANEALRLAAVGVLDVKLTVRSEKELEHLSYLRQGDASLYTPEALNTRMAVKSQTEFREVVREWWRWLPLVTLPLDQRITDDEKMMPTDMRGMTKPVYCAMAQIIQRALLPRFGLKPNPAYEPEEDWAFDCKGRRFLLFPQLLNALFELADMWCPTTEAADYVIMLSELLETCKTLESRHGLFSKLIRKYQRRYGARDEHELPISGGYVADYSTTAGRAVGAAGGGGAQAARDAPDEADQALKMATVEDEEDPGHKAATNWWAKIMERNKKFMEAKAARLAAEAVAALAAGAKAQQEPEKIHLSPIHEALHWTASGHTSPDISESGALPPVTTESGQSGIMVPLAFANLLPPAGVALPPELDKDTTAGGGDGGEGGDLERGGLRVQYMGKGVKGQIGGPAGRPPPVASHLRELLKAALVEVGASNDKGEAASVLTEDGTIAYNQVGPTTMVELINVLVNDKRMSTKNLRLLMGSFHYGASPSNASPAGGTPAVGSFIGGLDLVPDEAPPAVMTTALNAAAAAAAAAGRSRLAVSSMMTPVSDSPPVSGSGGVEPLDGKLAAEAEGGDAPPSPQRAGTPSSPLRAGTPPPPPPVFAARPRTPQLDPVTLAAIRAALQDAGFKPSELSDLLSSHGAGLSSDVRPEVISRVAQTLAASGFDTPALVAFLFPREPSASGEALDPDHPDHPGHRAGHLRPLTPVQLEAMRLALEKAGVDKAHIDLVRSWGGDIRAVQAVSAALEAAGFTPMEIHRFIAPAASTALIDALSRGGLKAGAAAGLVKSDGSGLALELDPRDLADAADAMAMAGFTAPQMVKVIGSDAAAVPPLEPAGMAACRDALLAEGFTTEELEGVVLTTDSTALQEGVGAVTLARVVGALARGGLTSDAIRRFLRYDMSRAATISLSQAAISAMHNAIEAAGLNGSPNRFIVPEQGVVPMMPGGAAVAPEASAGLVAQVGGALVEAMFTPAQIRAFLMPDVWEGEDDDNPGLLLPGPSAYNTVSGAAGTGSSPLAPRSSMTSGAARRRLFLSARDVVVFRAVLMAAGFSTEELMRLVHPDGRGLDPDADPDLAARAVAALASSGFKGHEIQLFLQLRDPAPAMTPAEAGAARGALLAAGFETQELSDLLRCDGLGLMVDPEPEPVFMAQVAVVLAGAGFPTFHICQYLSPELPAVPLEVAVVGKYWAMGREDGLSSSSRAPSRAASHAPWMVASEEQTGFTDSDSDDEEGGDESEDPEGDGESSEEGGELEGEEGREDGDGGEGPAERAVDGSLRTGLPPAALARPTTDATADSSSPAVTGNGDGTTPAAAAKPRPRVKLMEPGQDGEPESSARASNARAGDGQGAAARSAAAPPPELGGPGGARRAALAKPPRSALRTGAGAAASVISRGGMSAMMPLDMEEEDEESPLAKLALPPHTLAAMRAAVMRRCKGLSVKQLRQVAPHMGMPAAQVAALAAGNDAPSAAPAPAAAPPPPPAKPKDNTPPLPPPPSFLGLLAATAAATAPAGAAPNSGAAAAGTASSAAPAAGASSGATPAGAQSGSAAAAMGAAPSFSFAVPAAAAAIGPPAPAEPAKPAAAAAPTAAAKGAAGGAPAAAPAAADDKDKDKEEGGGSISIGDRSWLPSDPVVVGRLCQALSYEGFTPYQIRCFFMQPAVAAAMEAIRAARAAAAAAAAAAQAAGGAAAYNINGNALNLSISGFSAFTGITGLVAPLGDAGDDVESQLAARLDRFDHITPSLLVLIKAMLRSSGFTDEHLSNLLSPDGRRLDPDWDSESASMMVAAMAAAGWPAHLIRLMLTTGPPVGALTPNELGFINDALLESGFSRRQLAQVLRRDHSGPGATVDPTTLAQMATAMAQAGFSSGQLCQFLGPPPVSSAANAMSEGSTHLSHPLLSPLIQALSAAPANAANTPAASAQPTLSRLAAANLSALNNATAASGAASGATSVTANTTTRSVGGPPIQLPPKAPLSTGPPPADTTAAAAVTANTVPLPAIVSYTNYNAAAGGETLSSRSVMDIRNVAASCGIASAKLLDMVRPDGRGLQPHADPRVVERVGFHMATHGYTPAQVQRFLLPHGGCDYGRLDAATCSAIRGVLVAAGFKQNDLKNYLAGNGQVATAAAPAPALAAMAYALAAAGTTADQIRQLMRPTATPAVAAAALAAEKAEKAGGTKAADAAAAAAAAGRAAVMAVVTPEVCEVICNALRVSGYSMSQLTRVLRHDGTGLRADVGPLRLAQVVAALATAELPAQTIRMFIRPMGGVAPSLAANIKMTLERAPGLGPSKVAAVFDGNELKDDVDQSTLADIATALATAGFPGEVIRRLIGHPSCFVFAPPAPPEARGGPSNSLSALPEMQPPAMSAAAAVAVGGTGISPPRARPSAPGGGGGGGGGGGGGGGISSNPAIAAAATAVANATVRDMSGGGLVGGLSPTVCAPPALPPAKQAAMREALANIRNAASTANAANAGAANAGGAAIASAATNAAIAAIFGVAANPTNAAANAASAAAAPAGAAANAGGGGGALTSAAAVAASSSSLCTTTSASSLGGLTASSAQPSSLVVLGGGGSTSLVAEASAASDIMMDPARVAQLLAEASYSPEDIQAFLGMEFKQYQQPQQQQQQQQQQQLAAGAAGAVAAGAGAGAGAGTGGGGGGGGGGAAASGGGFMGLSLSSGMVGTTAPVLLRASASGMIPAGMTATTGPGGGGLSVQGPSLAPYRQSDPGAPRAARADRATSRLAAVATSSISVALDAAGAVASSGYEAGGGSGPLGGGGGIGGGGGGGLLGGGGGGGGGLLVGGGGGGLMVGGGGGGLMVGGGGGGLMVGGGLMVGGGGLMVGGGGLLGGAALGRLRGDALGNNGPLGRGTRSEQSSPMRQHPALSAAAAAAAVGPRTSLNGLGAAPATSRAAAAAAATSNASVATNPAHFFAADSASGAAGASEAAGSSPALAGWPDFEFRGWASGAPLVVAGCDAVLGWASGLRPAAGRPDGLPNGLEAQFAAYLHRLMWHLAGGDALKAAAIAAAAAVGADPAAASAAIAATADTAHPPPPLVRLLAAHLNRLLRRARGGAAAAASGAAPPPPGAAWAAWADGAAGGAAAGVMSTCVSALVHRPSSAAAGAGGGLSADAVAPSLLRFLVVSAVRQGLLQLGDGVGGGDGLAADVAPPPPSQQTYYNRTSMNGTVTSFSGGATAAAAAGNSGAAGYEGGAGGNSVAALLASEASSGSQVGPPVLASNRSRQQQQGAASPNEHLRALPVGYARAWGEAPLTRRLGPLTSPGGGGTGGGGFGSGGFGSGGFGSGGGGGSGPSTSYGAAAAAMMAGGGRFGSGGGGGGGLGSGGGSGAASPTSLVYRPLPQRQNPNVTAAKAGSPRETLPPWPLQRAFMYEEGAGGSSGGGSGGGSGGGAGPGNPSAPPSPGGGGSRQQAGGAAAAAAGAAGGLVLPPAVRPGSRGNSRPASPSRPVAADDGDHIGGGSGKLPVLTRAGSLGRLTAAADDSQSPALPITSPSGGHGHGHSHHHVGSPSARPLSGGPHGASALRSSSSLLDNLTSAPQQSQQQQQKQSEGDGGGSSAAAAEAALCRLLAELLRWLVAPLGLPDPAGRGAAQPQQWSGWLAAEKFRLRAQLARLGGAAATAAATAAAAAAGGAPRRSSAPPSRTPADAAAAAPAAAAAEAEAAGGSSSFMLTQLADFGA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BBN6</accession>
    <name>A0A836BBN6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_002455</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453125.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BBN6"/>
    <dbReference type="OrthoDB" id="19045at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046404">
        <property type="term" value="F:ATP-dependent polydeoxyribonucleotide 5'-hydroxyl-kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003690">
        <property type="term" value="F:double-stranded DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046403">
        <property type="term" value="F:polynucleotide 3'-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006549">
        <property type="entry name" value="HAD-SF_hydro_IIIA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013954">
        <property type="entry name" value="PNK3P"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006551">
        <property type="entry name" value="Polynucleotide_phosphatase"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01664">
        <property type="entry name" value="DNA-3'-Pase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01662">
        <property type="entry name" value="HAD-SF-IIIA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE/KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12083:SF9">
        <property type="entry name" value="BIFUNCTIONAL POLYNUCLEOTIDE PHOSPHATASE_KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08645">
        <property type="entry name" value="PNK3P"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="52"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="13"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="17"/>
            <end position="27"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2453125.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="242" mass="26717" checksum="955F0CB40A26A050" modified="2021-09-29" version="1">MSGRPRRAPKRSKKYDDEVDDFSDADSDVPLSDSDSDRKPRKKAAAAARGKKSLDAFTTDEGWSFEPPSIFYKEYGDAQPGDKIAAFDLDGTLVNTKSGATFAKDDLDWKWYNKSAPEKIQAYADEGYKIVVFTNQGTIKSAVKGKAAEKILARIDSIMEELGVPVQVFACTMDDHYRKPERGMWDFFVSRFNGGVAPDHAKSFFVGDAAGRTADFADTDKGFAENVGIGFRTPEEEFGVAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BC16</accession>
    <name>A0A836BC16_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Dynamin-type G domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_001663</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453440.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BC16"/>
    <dbReference type="OrthoDB" id="5061070at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005874">
        <property type="term" value="C:microtubule"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005525">
        <property type="term" value="F:GTP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003924">
        <property type="term" value="F:GTPase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008017">
        <property type="term" value="F:microtubule binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd08771">
        <property type="entry name" value="DLP_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.300:FF:001030">
        <property type="entry name" value="Dynamin-related protein 5A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022812">
        <property type="entry name" value="Dynamin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001401">
        <property type="entry name" value="Dynamin_GTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045063">
        <property type="entry name" value="Dynamin_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030381">
        <property type="entry name" value="G_DYNAMIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566">
        <property type="entry name" value="DYNAMIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11566:SF169">
        <property type="entry name" value="DYNAMIN-LIKE PROTEIN C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00350">
        <property type="entry name" value="Dynamin_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00195">
        <property type="entry name" value="DYNAMIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00053">
        <property type="entry name" value="DYNc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51718">
        <property type="entry name" value="G_DYNAMIN_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dynamin-type G" evidence="3">
        <location>
            <begin position="103"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="51"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="669"/>
            <end position="692"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="394"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="669"/>
            <end position="680"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51718"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2453440.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="813" mass="88874" checksum="06CA61BE5CE801CC" modified="2021-09-29" version="1">MSTSSRHHENPVYDRERDAAPGGDQHISSSHARAHHAGSGSGMHGQHKPGSIQVQAGGMVRRSQAADSSLRESTQELFETSEAQIRYRAYSRLQAAAVAMGESLAIPEIVAIGGQSDGKSSLLEAFLGFRFNVREVEMGTRRPLIVQMVHDPTAQEPRCRLQEEDSDEYGPPIVPETAVADAIQRRTEEHLRKMGGIAVSSKPIVMRAEYAYCPNLTIIDTPGFILKAKTGELDNTPDEIMSMVKAQASPPHRMILFLQQSSVEWASSLWLRVVQEVDPYFQRTVIVASKFDNRLKEFAERWEVDKYLSATGYLPPNVRPFFVALPKDRVIQSSAEWRRSMTEVDAAIYKHMRDGIKGGFDEERFASRIGFSNLKKFLEEELSRRYREAAPATLALLQERCDAVSAELMAAEIRLKSAEDVGALRRAAMKYADTVARQVVSLLQGSAEPDPVQHGLTTDEERAASRAPQWPGVSGASVQPLHHDSKLFGGAAFERCLEEFHMAVAHTRFPTSMSNDRLRNIMYAYKGKHHNGGAAKAAEDIARQAAKEALGPLLDAACVRLAFILRRLFDIAADRAAATMGSKDNLHPYISFHAALRSAHQSFISRLEEQARAMLRTHLEAATSQFAMNMYAHVPDPGDPLDVDEEDGDADGAGEDAEVLNERLKAVQLGGGAGAPGGPGRFEDNTPSRRATKSRRVALQNAGGMGGVLAGGGASSSDDVVSASEALFRKIRLAVATQYAPATLKSTFLDPMTDRLGLEVSLDLFARSDSDFGAMFSAAGAVAALASKRDMLARRVEGLIKCKNEFQELAKCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BD03</accession>
    <name>A0A836BD03_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_000812</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BD03"/>
    <dbReference type="OrthoDB" id="545471at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2454987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="111" mass="11921" checksum="62C3BB1A99DDE99C" modified="2021-09-29" version="1">MTSQGAGQRAAWLEAKCGALTKEVDALQAKLHDLHSTDLMSLRRAYKSLAQHVQALEHLPALLERAAEPSVTPEWVAGQTRLVAGVSAAVYAVGRLLAAMKVRGAMRSCEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SBZ5</accession>
    <name>A0A835SBZ5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_015164</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000123">
        <property type="protein sequence ID" value="KAG2424492.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SBZ5"/>
    <dbReference type="OrthoDB" id="10266058at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd12230">
        <property type="entry name" value="RRM1_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12231">
        <property type="entry name" value="RRM2_U2AF65"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="209"/>
            <end position="309"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="344"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="73"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="425"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="600"/>
            <end position="621"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="635"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="84"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="122"/>
            <end position="134"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="142"/>
            <end position="159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="430"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="507"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="639"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="665"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="686"/>
            <end position="700"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2424492.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="737" mass="73904" checksum="416F170C83A5ADDC" modified="2021-09-29" version="1">MQGNLANISEASEHLPDSLSPTGTLLGGAPQLAGTVGADQRSGYVVTELGIDSADHSPRQDAATGVVIGSETGLAERMSGGSGVSVSVPSGTPAEEAEQPPPPQPGHFQGNPASPGLVQYGPLGGAAAGSGGGVSSVRAAPVAPPPPPTQPHPGQPGEPQPSQQLWDELRQRDAQILVLQKKLAHFRSWLAGVHAKVQAANPSAINNYKRLYVGNLPPHTTEEDLKAFLHGLMVRTGANAAPGNAILSCKLKSAPGAGGGLPPPGLPPGPPDKHYAFIELRSVEEASNAMAFDGVAFRNAYLKVRRPSNYDVATAMMLGPTTPDPTIDLSQLEICRTVVENSPHKLFVGGLPCEWSEDMVKELLAPYGTLKSFNLVMDKSTGKSKGYAFCEYSEDSSADLLIKNLHMRRVGSKALTVKRAMEGNRSAAGSMGGSAAGGGGGGGSGGSSGGGAPPLTLSPAGHSGSLHHTPLGGQHLGAHHSHATGSIGSPPPLPLTPVGVAAMAKLASTSPAAPSTASPAQQHQHQHQHQHQQAGAASGAAAAAAAAAAAMAAALGGVGPDTSSQTALQVADAITALLQQHSGHLASRNLLAAAAAAAAAAGGGHPPGTPPPQPGAASTAAGIAAALQQFQRSAELAGSGAGTSMAGGTGASSGELQAVGSRGQGHPHQHHQYAPHQHAHAHHQHQQQQQQQEAAAAAAAAQEAAQQQFAAAAAAAQQQGVGPFDLSGLTGQGMGFW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SEC9</accession>
    <name>A0A835SEC9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pherophorin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_015031</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000116">
        <property type="protein sequence ID" value="KAG2425424.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SEC9"/>
    <dbReference type="OrthoDB" id="545621at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48184:SF1">
        <property type="entry name" value="MEMBRANE-ASSOCIATED PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48184">
        <property type="entry name" value="RICIN B-TYPE LECTIN DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="19"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032607851" description="Pherophorin domain-containing protein" evidence="2">
        <location>
            <begin position="20"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="158"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="182"/>
            <end position="198"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="202"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="264"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="291"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="325"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="361"/>
            <end position="406"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2425424.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="452" mass="44908" checksum="EDD2C7C019626EBC" modified="2021-09-29" version="1">MRLLFAAALVAAAVTCVSASPDITCTGTIYVKSGYAGASYGITLTPQGDSDRSYVWDLKDVPSGVPGKPTWDDLANSMKLSCTCLDDNTASCAEDYGEVILRVWAEPGSRGNGGGVSVNVTCAAAADGKSCAGAVSPMPGGWGSRLSAIAILYNDPEFRLPKSRPKTPTTPAGAPKPSPSPESDDNDGEDEDEDDDDDRSPSPKPSPSPKPSPAPSPSPSPKPSPSPGPSPSPSPVPSPSTEAAGSNADGAGDDDDDDDNRSPSPKPSPSPKPSPSPKPSPSPKPAPGSSNRKKPSGRNRPGGKKHSGRNGRRLLQAAVAVGRRPVSSGTPAVSTSSSISAPAPSVSVSSSGSAVVRTMPSPAPPSPPSPPSPPSPSPPSPAPPSPSSATPSPPSPPSPTSSPKPVPSTSASGGVARKPGKSGASGSGVGRRRTPSKSGGGGGGLPRKPRGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SGD0</accession>
    <name>A0A835SGD0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015091</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000119">
        <property type="protein sequence ID" value="KAG2425041.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SGD0"/>
    <dbReference type="OrthoDB" id="346907at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="372"/>
            <end position="434"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="482"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="821"/>
            <end position="854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="388"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="504"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="505"/>
            <end position="529"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2425041.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="864" mass="85435" checksum="E58D615A82F5C1DD" modified="2021-09-29" version="1">MDAKEADTFLHSFDNSHRVSISRNVTVRGEHPHTLLDARFLKRRVHLAGNATLTFERLVVARGRQPSATSASSLDVLSLSGDAAVVFRDVVLAYALCVPLAVTMKYGPAVPRPPALAGATGQEQQQQVLRLLPGEMCVPELAAPRPGGGGKPLLSPNCWNDSVVMVDYAIQGSTLDPAGVRVNQGTVLNLNTTFVCEHRVPLECVGAKGLPACVAEAVVALGLSEWDSYDLAPAVAPSPPPGSGGPGAAGGSGPPVLAVVLPCVLGGVALLAALAGGVWWWRRRSAAAGAPYQHHLQHKAGGGGGAAYGAKGGRHNGATAVTAANGKAAAAAPGDDLALAPRSGSSSSGLLLGASPTTAAAAATYTYTSTGSATTTATWPSLRPGETLPPQRAATATTLPAPQPTEGAGAGGHQQQQQQQQQQPGGAGGHGLHTQLNPYLVHSVRPQASHASTTADTATATSATLTATTEAQLANPLQLAATPSSRQLQLQHLQRQATAGSSSIEGGGGGGGGGGGGRAGSAPGAGAGAAVGVSGDVGGASGSGAHGSGLAGSGSHSGPLVGAVGAVGAVAPPPLVPRLDLVLGRDVVASREAVLGRGTFATVLRGQLLTSAPAAAPAVAAAAGPGSGGGALQLGLQPLPLPAPVPVAVKLFHRDVVGGTCEDIKSLQQEVAILARCRHPNIVALYGAGSTADLPHQRGPKADEGGGEEHVEEDIADIGDRELPGDGISASVVTGGGAQTRFEGDDVLSFGAGFGRVRRVGQDVDEGEGGQAAVEEAGEGGPQIRMWQVGVEAAEVAGGVGDGAIGWELGGVVLLDQGHDGVGGEAQPRVGAGQGRAPHVGELDGGSTQDGGGKVAELCDGAAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SJL9</accession>
    <name>A0A835SJL9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_015148</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000122">
        <property type="protein sequence ID" value="KAG2424668.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SJL9"/>
    <dbReference type="OrthoDB" id="556813at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="39"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="36"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="31"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2424668.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="92" mass="9412" checksum="9743217AE3BC257A" modified="2021-09-29" version="1">MTPSCGPSSSNPAPASAASAAAAPGSQNQQGARRRRRPGGFMLVVAAGVAGVAAWVALTVKQTDALSQDQATIKGRLDSLERSALRLPWPSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SPU3</accession>
    <name>A0A835SPU3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013533</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000076">
        <property type="protein sequence ID" value="KAG2431003.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SPU3"/>
    <dbReference type="OrthoDB" id="550145at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="209"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="486"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="571"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="77"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="209"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="414"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="425"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="486"/>
            <end position="498"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="508"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="575"/>
            <end position="591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2431003.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="679" mass="67774" checksum="E175DADB208FA54B" modified="2021-09-29" version="1">MLQALLAAKADPNKPVGLPHEYDLTPLQLAAALCRPGAVSQLLAAGADPSATLVKRSSSKPIRPPDGRPSDYGDQQAAATAAVLAAATATSSNRARSQQQHNQHQHQHHNPPPPDPHGGGLQAPPLIDANLGSAAEGDTPLHTAVRQALEPDLVPLVLRQVAERGLVSRADVQEAVGELARQRLGGAFAALEALLDASGAATATATAGATAGAAGPGSSSNSGHSSGGGGGASSRDSQHHQQQQQQQQHRRQPPSAVHKANAAGATPLGLALAEPQDSARNCVALLASHPALDLVGTDVVLRAVGQRSRLPHAHLLLAAVQERAGAAAAAAAGGGGAGGVAAAAQRLLAAALSLYCGDRELVQSQTLEQARMALSVARSSARMAADRGWAGGRRPRLQQLQLQLQLQVRSTVAPQPPAPQPAPQGPAASGAGQSPQRQAQPAQAPQSPQQPAAAAADGSSTPQPSPATLAAAAAAAAAAGEAAVATAAAQPSQQPAAQGDDGGSRQLPPLPPLPPPPPGAVAVRLLRKTLVMAGVGLLARGLLGRRSTLRVALVMATAGVLTDGLWRGGGDVGGQRDAAGRQRAVGRQRQGAGPGATGAGAAAAAADGGDAGGLGGECCVCMSTKAVLGFVHGGVVHNCICASCMREMEQRYGSGAGSRSRRCPICKAHAQAVVRVVST</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SPZ4</accession>
    <name>A0A835SPZ4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_015158</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the Iojap/RsfS family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000122">
        <property type="protein sequence ID" value="KAG2424680.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SPZ4"/>
    <dbReference type="OrthoDB" id="21330at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043023">
        <property type="term" value="F:ribosomal large subunit binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0090071">
        <property type="term" value="P:negative regulation of ribosome biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017148">
        <property type="term" value="P:negative regulation of translation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004394">
        <property type="entry name" value="Iojap/RsfS/C7orf30"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043">
        <property type="entry name" value="IOJAP SUPERFAMILY ORTHOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21043:SF0">
        <property type="entry name" value="MITOCHONDRIAL ASSEMBLY OF RIBOSOMAL LARGE SUBUNIT PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02410">
        <property type="entry name" value="RsfS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="190"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="236"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="327"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="452"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="690"/>
            <end position="941"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="236"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="335"/>
            <end position="351"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="359"/>
            <end position="380"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="452"/>
            <end position="485"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="495"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="690"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="754"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="776"/>
            <end position="785"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="790"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="845"/>
            <end position="855"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="872"/>
            <end position="908"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2424680.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="941" mass="95745" checksum="E833A396BA7A7148" modified="2021-09-29" version="1">MLHSLQKRTGSVDFDFVFAQNPAAQEQLREAARDSIIERLSVVLGRRKGRRLDAEALQRLQPEELAAACTQARLPAAAFRDAPTMAAALHAFLYPRDGPADVLGPSAPAPAAAAAAAAAAAAAASTARAAQVLGAAAGGLRSGPAVAVGAEGPTAFQRASWAAFGEGESRAGFPGAGGFGAGAGGGLGVGASSGSGQSTGLEAEEQEAEAARRAAEAAEAAADALLEGELGRRLSALSSSGSSSSSGGAAAVQPQKARRSPLFPQSAPQGHPDHLCAEGGAAEAAEAAEALPPALPDGATQPASSVVSAAQFVPRSYAPASVPFVHHTSTEQQEDQQLASAAAAAARQAPQRHSAGDGPLPPPGSPYAPLPSPHAAPPPGEVLRAVRRALSRRGYPTKDPGQLRSVLLLSRPQLLDILGDFNALPGGHGAGLSREQLAAALLQLTAAPDRGEAAAAGSSSSRSSSSSSSSSVSRANSAASAKAASGRYRQLRMNEAAREEEHHQQRERSQAAGAAAAAEWDEEAAAFGDPRRREVLAAARRRRQLMQAAAVPEEIATWLVKARAQDVMLFSLPSPAGAATHAVVATALSQRHAYAAAHAVRYQIKDKLEALVAEEVEAQAQAQARSKAETGASAGAAAAAAAGPAAVPGPPAVAGVNGSDWLSLEAGSVQVHVLTAPARQYYRLEELFGAEEEEEEEEEEEVEEEVEEVEEAEELEEVEEAEELEEEEELEEEEELEEVEEAEATRYGHGPDTAAAAAAAAAGAAAAAAAAAAGLGHRGAGGGSLRGARRQQPLPAAMQAPPVPHDWWEQRGPGQPPHGHELRPGQGPTTVVGPSRVGGKHDGEAAAAAEAVQEPGPGPAPLQGARRRLQKAAAGAEAEAEAEAATGAAAAAQGQGQGQQQQQQQQQARARRPRVQLFGPGAAGERQPDTLETAQVGAGQA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SR77</accession>
    <name>A0A835SR77_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_013813</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="5">Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. GCN2 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000080">
        <property type="protein sequence ID" value="KAG2430336.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SR77"/>
    <dbReference type="OrthoDB" id="25592at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050339">
        <property type="entry name" value="CC_SR_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 2-ALPHA KINASE EIF2-ALPHA KINASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11042:SF186">
        <property type="entry name" value="KINASE, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0418">Kinase</keyword>
    <keyword evidence="2 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="214"/>
            <end position="514"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="133"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="46"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="159"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="246"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00037982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2430336.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="518" mass="54565" checksum="8C0E59E8C17C7748" modified="2021-09-29" version="1">MSLETKDDTATQHISTTGMASSPGGEVTAAGTPLAPPVTAEQQPPAASTSARSSCSFGSSNSTSSCGSAGSDDTVGRSSLLLSDDGVAAFRDGAEEVEGEEKEWVSGGSAEDAAAGCAEAPVAEVITITDNTACASPPSNAEEAPAAASTQREEAAASDNEEGEYYEDDVDDGYYENDEDYYSDDNEEGEEEAPAPMSTEETKAYLAAHGLDTCVTLAELGTGGFGAVSLVEIKLPDGTLIKAARKVLNQNGRDGGLAALRAALQRELDGLAAAEGCEHAVQCLGHKMPTEEGEPAELLLTYSEGGSVAGLLSTLAHTYMRGLAEAPERKRSGKNKYKYEQLPYPGSTLMDEQDMRSMLRALVLSIKHMAARGYLHCDLKPANVLFDYAPDGSKVFRVCDFNLATRMGSDGSIPRAPGGTFGYCAWETHCQLVPIEQPRPHSITLAADIASAGLTLAAATGLHSLAGGTLAYLEYERDLPRRTPPALKELIEWMVAVDPSQRPSPDQVLAHRWMAGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SR87</accession>
    <name>A0A835SR87_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">MATH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013715</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000079">
        <property type="protein sequence ID" value="KAG2430351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SR87"/>
    <dbReference type="OrthoDB" id="6359816at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00121">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.210.10">
        <property type="entry name" value="Apoptosis, Tumor Necrosis Factor Receptor Associated Protein 2, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045005">
        <property type="entry name" value="BPM1-6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002083">
        <property type="entry name" value="MATH/TRAF_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008974">
        <property type="entry name" value="TRAF-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR26379">
        <property type="entry name" value="BTB/POZ AND MATH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR26379:SF187">
        <property type="entry name" value="OS07G0655300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF22486">
        <property type="entry name" value="MATH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49599">
        <property type="entry name" value="TRAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50144">
        <property type="entry name" value="MATH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MATH" evidence="1">
        <location>
            <begin position="39"/>
            <end position="178"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS50144"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2430351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="428" mass="43016" checksum="AD0EEE2EED6EB474" modified="2021-09-29" version="1">MPSPETSDSEVEASPFVGRYTGGTGCLATQSLRQVDTVCGTHTYSLAGYTLARAMGPGTRLCSDLFEVGGQLFRLEVYPAGLDAAGHKYLGLFLTTPGSCRPGHLLYELSVIDKSTLKPVHITESRTAATPPPPAPATLQAPAPGVVAGFPRFVKSNFLHRNSRRFLHDDTLTIRATVKMLTGWSSFPVPPPAPQVFALHPTSPGALAAATAAAATGAVGGLPPALPTTAGGLTLIPPCAALAPQQTQTVLQLQSQQQQQLLYSGLQPAMSAAGAAYMLATVPPAQLQQAAGWTAGYPCPCPCSGGGASPAQHHGAYGSAGGAPALLYTQQQQQQPQQLQAAAGWQQGMSLLSHGGGGGGGGGLAGVGSAGGSGPPLTYGYGGAAALVPAQGTAPAVLQAGPGGHVTYGGGHTAIWQAPPVAVGTAPF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SVB2</accession>
    <name>A0A835SVB2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012448</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000059">
        <property type="protein sequence ID" value="KAG2433987.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SVB2"/>
    <dbReference type="OrthoDB" id="9973266at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004422">
        <property type="term" value="F:hypoxanthine phosphoribosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032263">
        <property type="term" value="P:GMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046100">
        <property type="term" value="P:hypoxanthine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032264">
        <property type="term" value="P:IMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032265">
        <property type="term" value="P:XMP salvage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06223">
        <property type="entry name" value="PRTases_typeI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.2020">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029057">
        <property type="entry name" value="PRTase-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000836">
        <property type="entry name" value="PRTase_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363">
        <property type="entry name" value="HYPOXANTHINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43363:SF1">
        <property type="entry name" value="HYPOXANTHINE-GUANINE PHOSPHORIBOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53271">
        <property type="entry name" value="PRTase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0328">Glycosyltransferase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022676"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2433987.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="209" mass="23766" checksum="F247B0C13A59B314" modified="2021-09-29" version="1">MHISYNEIHQAIADCVEHTDVYESFKPTLIIAIGSGGFIPARMLRTFLKAKCGKSLPIQTIGLVLYDDNLDKYDPETAVVRKTQWLNYSHGEGTGISLQGHNILIVDEVDDTRKTLSYAVAELAKDAEKQRHDYEAKRKGDEPEWQPPKLGVFVVHNKLKDKEGALPEDLLASRYFKCMDVPDNWIVYPWDALDIEAHQQRSDERRAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SWG7</accession>
    <name>A0A835SWG7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Pherophorin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012392</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000058">
        <property type="protein sequence ID" value="KAG2434378.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SWG7"/>
    <dbReference type="OrthoDB" id="538826at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032277290" description="Pherophorin domain-containing protein" evidence="2">
        <location>
            <begin position="28"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="41"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="46"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="79"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="99"/>
            <end position="112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2434378.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="243" mass="25703" checksum="290DBA90204DB28B" modified="2021-09-29" version="1">MAPLGRGFVWLQLVVFLTLALTQFTSSNIIKVDPDTQAWKVDRPASNHHKPASSKRHPPSLRSPAGGRRVLHPPPPQQQPGGSSPSAGPSGDRDIPLPADTPSPAASPPPPPALPPALKVVFSLEWNFTGDVDIVVSPPPPANTTISFVQKGCLTCPSTGYGRLTTPKTNARSGPETVEFETPLLGRYSVCALYMTAANITGRVAIPARGVSRAFAATTTGRALNYRACDATEPGYIFSYDLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SYG7</accession>
    <name>A0A835SYG7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Lysophospholipase NTE1-like P-loop domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011769</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000052">
        <property type="protein sequence ID" value="KAG2435473.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SYG7"/>
    <dbReference type="OrthoDB" id="421051at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056556">
        <property type="entry name" value="NTE1_P-loop_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF24179">
        <property type="entry name" value="NTE_Ploop"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Lysophospholipase NTE1-like P-loop" evidence="2">
        <location>
            <begin position="5"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="72"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="213"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="216"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="3">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF24179"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2435473.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="284" mass="26767" checksum="588614733407308B" modified="2021-09-29" version="1" fragment="single">MRRQVTSWMAAQEEEYRFIVLEADVAASPWSSVCVAQADCILLVAPEGSEPQLSGPESLLVFNAASPAFARPKAARSGLTPGGPTAPLSRGMTPAASAAHLGGVAAAAAGAAGAGSPPPAAAAAAAPGRSPLRFSGVAAEAAAAAEGGRGSGGAGGGGAGGGGGGGGGAVGGVGASMHPFQAKGLAHQQLYGGASNPAMLRRVELVLLHSTAASNSGGGRGGGPGGGGGPGGGSRAGGAAGGGGGGAGAAGANIPHGTAQWLALRPNLSRHHHIRLSRTADIQR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SYH0</accession>
    <name>A0A835SYH0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Reverse transcriptase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_014409</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000095">
        <property type="protein sequence ID" value="KAG2428226.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SYH0"/>
    <dbReference type="OrthoDB" id="545196at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000477">
        <property type="entry name" value="RT_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19446">
        <property type="entry name" value="REVERSE TRANSCRIPTASES"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00078">
        <property type="entry name" value="RVT_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50878">
        <property type="entry name" value="RT_POL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Reverse transcriptase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="163"/>
            <end position="180"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50878"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2428226.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="180" mass="19919" checksum="F6449291D29F6900" modified="2021-09-29" version="1">MLSKAISNRLQPALDAVVDELQTVFITGRWIGDNALYHQALIEWMRLDVDADGALYFLDIEKAYDRVHRQWLYASAEGLGFGPRMLHWIRLLTANGSARVCVNGMLSDPFPVLNGLPQGSTASPPLWVIQLQPLTSYLRRQVEQGALHTPLLPDGTPAPPAGHHADDTTLTARDPRCGWA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SZM4</accession>
    <name>A0A835SZM4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_011643</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000050">
        <property type="protein sequence ID" value="KAG2436134.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162894at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05579">
        <property type="entry name" value="STKc_MAST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000147">
        <property type="entry name" value="probable serine/threonine protein kinase IREH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001418">
        <property type="entry name" value="Serine/threonine protein kinase 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058783">
        <property type="entry name" value="IREH1/IRE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26031">
        <property type="entry name" value="IREH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="892"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="337"/>
            <end position="368"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="483"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="860"/>
            <end position="885"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1047"/>
            <end position="1136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1297"/>
            <end position="1334"/>
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            <begin position="1466"/>
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            <dbReference type="ARBA" id="ARBA00048679"/>
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            <dbReference type="SAM" id="MobiDB-lite"/>
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    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
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    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
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    <sequence length="1656" mass="175815" checksum="BB73D600D3682370" modified="2021-09-29" version="1">MDDLALLSRSGQAPGPGHFGQPGRSRAAPKRASVAGEAVIYEEQELQHPYPGVERSSSAEHRATHAAVRLASVPQAWDRCNSADGVDPAVAKQLATAVESKLKLAPLLAKRLERVSHSSGSFSSRSVTIVNSGQPVPSGRNTPQRRISGADYNKLNYLVTSLEGARGDRGLKVEGSARLPQVGFKETGGSPTTSKNGAANNHNFEEAKRQVDRDLRLFLEDVRDLYAQISLREGADVPIVLEVIASIMDIAEECLETPIEDFKLTITDIVDNIEEERSACQQRTIRALYTRLLFILTRCSRLLITEQQHLFATEPRNRRRHSQVFGPGFTTKTQKELGLHLPPQQQTSDTAGSTPKEEEEEPVFRSHTMPVKTMITMAQRLKQERPLDSGGWAEPPQLARIESEQLPESPAGPVGPVSASGQLELNTLRHQSQSSDLEGFGGASDSSMTSASKKKKSLFNKISKGIKNFVADGFKRKVKEGLKDAPDGLQRPQSEMGPAGHQQPLRFRIGSDPPRATDSPGGSRRGTKTGVSDGNLDGNPPAPTRKLDQQRSVRFQETPVTIIGENDDSASRRPPERDRTSGSCSAGGGHAHAHAHPHPHSHSGASLSTGGGTGAAPLSPDADADADLDLENGKRAKLMVNTEGPHTPPPTEPGGMGMDPSERTSASPQPSSELGARGTGRAKPFRRASVDLFALGHMMPPGTEPMSPDGAAPPDDLSVICSICEEAWLSTHLEEHSIHCAVLRTLSGNGLSIDAQLTTIANVLEEWLETPLAFPALGPAPNVFHVKNQLMKLIKAARNAAALQPDGSKVPTTRCFSIQAELGEMLETAEQAGKLAVVTQTYAHRVMRLISEKVNLLAETGGPRQRAQGGSDAGDSGTSTPRSMPGMSIEEFEIIKPISRGAFGRVYLARKLATGDLFAIKVMKKRDLIRKNMVESVTNERNILAMAQNPFVVRFYYSFTSRENLYIVMEYINGGDCYSLMRKFGALDEEVARQYIAETVLALEYCHAQGIIHRDLKPDNLLINAQGHVKLTDFGLSCVGVIDRTDNLNGSQPMDTDGPEHEGPDSTWGPSAEGNGDAMDASGPRPTDDGPISNISLDGALQSGSQHGGANGRMSVPGQALGGAASSLGLPPRPVGQHQRIVAPEHESRRAVGTPDYLAPELLLSTGHGPEVDWWALGAILYEFITGAPPFNADTPEEIFDNILDRRITWPDEDDMSCDCRDLIDKLLHPNPLKRLGHRGAGEVKLHPWFEGLDWTGLVRNKAAFIPAVEDETDTSYFESKHVSQRSMAEDLDKLRTSVAGGSERSSAQVGPCSGPAQLGVGPSSGPPGGRTQVDRLKDAYYREGSGLRSVGSSNSHGSSHMSRTSYTGQAGPVASGGQMMQCGPDLTSLDAATVSRMCSSPSHAIHAHMHSSGPESATMPHGGSYGGPRHSGNVVSVASGSLHPRNSVGSSSGVAPLLLGGVGARNSGSGGRNSGSGARNSGSGARGSASGSAGAGGMSERPSPGSIGTGAGGTMSGLNTCGGTGEGTDVGSMRGAGMYEEEAEDGYPDDEDYVGEEGVEVEVEEHNGEDNGAGLGDGGGPNSGRPRAGVLLDEPTAGTVSGSGDEEGIDLSHDPFNNFSFTNFTGLSAANMEKIQKLREHFNRRTSYSGPDQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T035</accession>
    <name>A0A835T035_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SRCR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_013375</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000073">
        <property type="protein sequence ID" value="KAG2431389.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="6477838at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
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        <property type="entry name" value="Scavenger receptor cysteine-rich protein type 12"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.250.10">
        <property type="entry name" value="SRCR-like domain"/>
        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.100.10.20">
        <property type="entry name" value="Vitelline membrane outer layer protein I (VOMI)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001190">
        <property type="entry name" value="SRCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036772">
        <property type="entry name" value="SRCR-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005515">
        <property type="entry name" value="VOMI"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036706">
        <property type="entry name" value="VOMI_sf"/>
    </dbReference>
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        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48071:SF28">
        <property type="entry name" value="SRCR DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23106">
        <property type="entry name" value="EGF_Teneurin"/>
        <property type="match status" value="1"/>
    </dbReference>
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    </dbReference>
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    </dbReference>
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        <property type="entry name" value="SPERACTRCPTR"/>
    </dbReference>
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        <property type="match status" value="11"/>
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        <property type="match status" value="1"/>
    </dbReference>
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        <property type="match status" value="11"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51092">
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    </dbReference>
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        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
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        <property type="entry name" value="EGF_2"/>
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        <property type="entry name" value="SRCR_1"/>
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    </dbReference>
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        <property type="entry name" value="SRCR_2"/>
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    </dbReference>
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    <keyword evidence="7" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="8" id="KW-0325">Glycoprotein</keyword>
    <keyword evidence="6 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <keyword evidence="2 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 10" id="KW-1133">Transmembrane helix</keyword>
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            <begin position="2327"/>
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        <source>
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    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="PROSITE" id="PS50287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2431389.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="4739" mass="477815" checksum="52E649632BAADA25" modified="2021-09-29" version="1">[encoded data, 4739 characters]</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T0X0</accession>
    <name>A0A835T0X0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HYH02_012014</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000054">
        <property type="protein sequence ID" value="KAG2435017.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T0X0"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08530">
        <property type="entry name" value="STKc_CNK2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000097">
        <property type="entry name" value="Probable serine/threonine-protein kinase nek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF6">
        <property type="entry name" value="SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10 11" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10 11" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 11" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="13">
        <location>
            <begin position="16"/>
            <end position="276"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="284"/>
            <end position="306"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="319"/>
            <end position="428"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="328"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="12">
        <location>
            <begin position="352"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="12">
        <location>
            <begin position="366"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="45"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="RuleBase" id="RU000304"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="13">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG2435017.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="474" mass="50320" checksum="A9605A855C48EF88" modified="2021-09-29" version="1">MSAGAGYGGLPKFPNFKVHKLLGKGSYGKVYKVERESDKQLYALKEADLGSMSQAERADAVNEVRLLVSIGHHNVIRYHEAFLLGNKLCTVMEYAPFGDLRYYISKGAKLRTPFPEEAVWRIFLQLCKGLQALHSQNIIHRDIKPANIFLCANDLLKIGDLGIAKALTSMNFARTQIGTPCYMAPEVWSGRPYSYSSDIWSLGAVLYEMMTFRTPMEGRTMADLRNRIIGGRYTPIPPGRYSPELTGICHSLLATDPAKRPSPSSILGSSAAAKWMHILPAAGPPARRWTSDGAPAKPGAGGGLGLMDTIVVPRDLKQLPKRLPPPSYDSDAAAARPAAPQPPSAGGPPGVQRSSSWSQGAAIQVPSSAPSSAPNSKPPTPSGGAQGSKAPSRENSRAPSPDVRALQDNRKGAGGPGAPLPPLFPRVPSGGLNPAAAAAAAAAAAYGQRWTPNAPPLAFAVPRVPVPSRRVSYS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T1U5</accession>
    <name>A0A835T1U5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012350</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000058">
        <property type="protein sequence ID" value="KAG2434328.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T1U5"/>
    <dbReference type="OrthoDB" id="529546at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039715">
        <property type="entry name" value="ZCCHC10"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491">
        <property type="entry name" value="ZCCHC10 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13491:SF0">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032610405" evidence="2">
        <location>
            <begin position="24"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="59"/>
            <end position="94"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="153"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="206"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="622"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="724"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="928"/>
            <end position="952"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="162"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="224"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="634"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="724"/>
            <end position="757"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="764"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="821"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="936"/>
            <end position="945"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2434328.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="952" mass="96183" checksum="E68EE292375057A7" modified="2021-09-29" version="1">MRGLGLTVAALVALAALAGSSSGGGGGSSAGDDSLPSVDRLLAPLLPLVVPDAGGANWRLGEDFGDQPSAGAGSDAAEEESDGARVGQGRDTIRGGLNPGELRAALRALEAVARLPRVRASLGLYRVHELGEPRVRPLVEALLAELPRALAEAEGAEQPQAGAEEEGAEGAGGGGSGSEVLEVLRGIQAGVRSLLGLPPDASSPMLDMIKGGSSSSSGGSSSGSSSGGSSSGALSYSPPAHSYPLLRRAAVARVAQLWLLHLLPAPAGAVWVLKARVLIIDILRQLFALHVAGMSSRHVLEFMHISKAAGTSLCKTAEASGCAALDFGMGRTCLMREFDDTPRWLNASHHWAAIAPTAVPHTSHPLAFLMYGYPRSPKKARSCPQRLSMLKKMRLDFFANEYTVYNDAVLGSKAITAQWRKAGSSNSGSSGSSSSSSTADAEEAGRAAAAYTAYVVHMSAGGREGPALVGPEAAAVAAAEVDAEGGMGAALGEAAEARRGMNASAAAAAATGAAGGLFRRAYSDVVRGTHLCRRFAYAIALRDPAARLRSHLLFIADTYLRSYGRPGLVAAFEAGRNSSAWWRSFAPPLMDNYLVRSLGGEAVFALPPGAIGGLQLQLGGGGGGGGGGGGAAEAGGSQAAAEQQQQGAADTGSAASSSSSSSSSSPSSSASSSLPPYLALAEAVLAQMDVVLVLESDPALSTRTTTYGLGWGPSLADFALRRSSSSSASSSGGSSTSGSSGSSSSSSGSAHGSTAGGWEAVLSSGGGGGGGGSEARREERRRRLQATDGEERGRGRRRRGKEEEEEDEEEGDSKAGSEQQGAGSEAGTATATATSGKAAIGSPLLQLLPRLSVIRELEAEAVRYDNLLYGWGRLLAALDDVVWRLAAAGGVEPVPGLFARGGRGEDGAEVVPPKCGYIHLTDGGVGGGGGGLGGRKGARRARRRGLLPAESG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2022-12-14" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T1Y3</accession>
    <name>A0A835T1Y3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012400</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000058">
        <property type="protein sequence ID" value="KAG2434388.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T1Y3"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032565163" evidence="2">
        <location>
            <begin position="21"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="124"/>
            <end position="145"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2434388.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="155" mass="15627" checksum="B96619074EC74C0F" modified="2021-09-29" version="1">MKVARPSGGMLSWLASPAVAVLPAGGGGLGSLQGLVADVDLAADMAVAAAAAGGHMGLLDRLLAVTAAAPPPPPQATWLAAHFWQDAAAAVMYSRCRLQQRQQRYSALWAGGWAGRLGGAAAAAAAGAAGSSPEEDEDAAGWGVEEQERWVVRGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T8A8</accession>
    <name>A0A835T8A8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">CDAN1-interacting nuclease 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_010420</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440543.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T8A8"/>
    <dbReference type="OrthoDB" id="1272at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029404">
        <property type="entry name" value="CDIN1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31661:SF1">
        <property type="entry name" value="CDAN1-INTERACTING NUCLEASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31661">
        <property type="entry name" value="SIMILAR TO CDNA SEQUENCE BC052040"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14811">
        <property type="entry name" value="TPD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="248"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="248"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="7">
        <location>
            <position position="298"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023480"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2440543.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="298" mass="31814" checksum="C3AB3A103716A5E1" modified="2021-09-29" version="1" fragment="single">VRCVHTDCCYSPLSDVAKQVTGLEYELYLQKRLAEAGLAFWTEAELRTMGFHKTPDCKLKVPVAVRSRSGGEHLVCWVDSKATFGDSRTHVKQVEEQYRTYVNRYGPGMVIYWFGYVDDLNTDPHVLLCDDFPDAASIIRITNALTLTPHLAQQQQQQQPAAALLPPAASATAAAPAAVPPAAGAASAAAAVAAAGVVRSGGLGAALGVGGRPLVPASPSKMARRVSGMAEPEPTSLRCWRAPAVPRAEASRGAAGSAPNDTCTQHSHRRAAAGRHRNWSAGRVSARDCNQQLRQLRQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T9H1</accession>
    <name>A0A835T9H1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">MPN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_010118</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase M67A family. BRCC36 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000036">
        <property type="protein sequence ID" value="KAG2441279.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T9H1"/>
    <dbReference type="OrthoDB" id="446074at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070552">
        <property type="term" value="C:BRISC complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004843">
        <property type="term" value="F:cysteine-type deubiquitinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008237">
        <property type="term" value="F:metallopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0070536">
        <property type="term" value="P:protein K63-linked deubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd08068">
        <property type="entry name" value="MPN_BRCC36"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.140.10:FF:000184">
        <property type="entry name" value="Predicted protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.140.10">
        <property type="entry name" value="Cytidine Deaminase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000555">
        <property type="entry name" value="JAMM/MPN+_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050242">
        <property type="entry name" value="JAMM_MPN+_peptidase_M67A"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037518">
        <property type="entry name" value="MPN"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033860">
        <property type="entry name" value="MPN_BRCC36"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10410">
        <property type="entry name" value="EUKARYOTIC TRANSLATION INITIATION FACTOR 3 -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01398">
        <property type="entry name" value="JAB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00232">
        <property type="entry name" value="JAB_MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF102712">
        <property type="entry name" value="JAB1/MPN domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50249">
        <property type="entry name" value="MPN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="MPN" evidence="3">
        <location>
            <begin position="252"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="200"/>
            <end position="227"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="215"/>
            <end position="227"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008021"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50249"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2441279.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="538" mass="57263" checksum="B97F6174BEC7E39D" modified="2021-09-29" version="1">MSFGGQTYQFADFLEFAVAPGALPSEITVRKVFKVSKPLRVKLSGSFDINTQEFRTKASVKERIFGGSIRFIPEEGAVEYRKRLSVFGLVSAQVWSRWDLLGPDANSPNSHHNGSGGGFFSRLTRPRVGCGLALGDVPPGCALLSAARLPALLVRPLSYSFKSSLPLSSVLRVKAYCDVTVRLPRRLSLWVDAHGAGGEAFGDEEEEEGQQAGVGVPGGSRAGGGGGGGAGLLVRLRRTALQTGARMSLERVEVTNEVLLAVLAHAHSTESEEVMGLLLGDITEPVRGGGAVCRISLAFPQIRTDRRKDRVETSPEQMARCSAHAERLTRETGSRVRVVGWYHSHPHITVLPSHVDVRTQAMYQLLDPGFVGLIVSAFNRDAATEASTVQLTAFQALPDVDPQAAGGLIRKEVRLALCAAASQLERSFSDLMVVQRMLLMEENEVYKKALASALAASSRSSAVGSGAFPTPELVELHHAGVYQAHMARLVQTALHPSLAALGALVAQQRAQAAQLGAEVAALEAQVAAQVATGAGGRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TA64</accession>
    <name>A0A835TA64_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Serine/threonine protein phosphatase 2A regulatory subunit</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_010536</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="4">The B regulatory subunit might modulate substrate selectivity and catalytic activity, and also might direct the localization of the catalytic enzyme to a particular subcellular compartment.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the phosphatase 2A regulatory subunit B56 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000039">
        <property type="protein sequence ID" value="KAG2439907.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TA64"/>
    <dbReference type="OrthoDB" id="10264446at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000159">
        <property type="term" value="C:protein phosphatase type 2A complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019888">
        <property type="term" value="F:protein phosphatase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000041">
        <property type="entry name" value="Serine/threonine protein phosphatase 2A regulatory subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002554">
        <property type="entry name" value="PP2A_B56"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257">
        <property type="entry name" value="SERINE/THREONINE PROTEIN PHOSPHATASE 2A PP2A REGULATORY SUBUNIT B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10257:SF3">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE 2A 56 KDA REGULATORY SUBUNIT GAMMA ISOFORM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01603">
        <property type="entry name" value="B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF028043">
        <property type="entry name" value="PP2A_B56"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="49"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="11"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00009745"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRNR" id="PIRNR028043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2439907.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="488" mass="56550" checksum="6724606CCCD136A1" modified="2021-09-29" version="1">MLKSMKQKFSGKKDASKNKDDSQPSTSAKAGAPAASSKAPAPRPISAIREKPPLPAINEQTLQQYYAEPLPSFRDVSPAEKQYLFVQKLHLCSFGFDFADPTKHVREKEIKRQTLLELVDYANSGAGKFTEGVSEDIIYMLSNNLFRTLPPVRSHGDAEGNYDAEEEEPSLDPAWPHLQIVYEFLLRYVVSNDTDAKIAKKYIDQQFVLKLLELFDSEDPRERDYLKTILHRIYGKFMVHRPFIRKAINNVFYRFIFETERHNGVAELLEILGSIINGFALPLKEEHKLFLQRALMPLHKPKCVAMYHQQLAYCVTQFVEKDSKLAEPVLTALLKYWPVTNSQKEVLFLGELEEILELTQAPEFQKVMIPLFRQLAKCLNSQHFQVAERSLFLWNNEYIVNLVAQHRHQLLPILFPALEENTNSHWNPAVHGLTCNVRKMFQELDEALYEECKRKYEEEQASERAAMETRDRKWEYLQKLAVQKSNGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TA68</accession>
    <name>A0A835TA68_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Cytochrome P450</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_012363</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1 5">
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2 6">Belongs to the cytochrome P450 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000058">
        <property type="protein sequence ID" value="KAG2434345.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TA68"/>
    <dbReference type="OrthoDB" id="548633at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0020037">
        <property type="term" value="F:heme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005506">
        <property type="term" value="F:iron ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.630.10">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001128">
        <property type="entry name" value="Cyt_P450"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017972">
        <property type="entry name" value="Cyt_P450_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002403">
        <property type="entry name" value="Cyt_P450_E_grp-IV"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036396">
        <property type="entry name" value="Cyt_P450_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050121">
        <property type="entry name" value="Cytochrome_P450_monoxygenase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305">
        <property type="entry name" value="CYTOCHROME P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24305:SF166">
        <property type="entry name" value="CYTOCHROME P450 12A4, MITOCHONDRIAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00067">
        <property type="entry name" value="p450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00465">
        <property type="entry name" value="EP450IV"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00385">
        <property type="entry name" value="P450"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48264">
        <property type="entry name" value="Cytochrome P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00086">
        <property type="entry name" value="CYTOCHROME_P450"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 6" id="KW-0349">Heme</keyword>
    <keyword evidence="4 5 6" id="KW-0408">Iron</keyword>
    <keyword evidence="3 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0503">Monooxygenase</keyword>
    <keyword evidence="6" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="binding site" description="axial binding residue" evidence="5">
        <location>
            <position position="150"/>
        </location>
        <ligand>
            <name>heme</name>
            <dbReference type="ChEBI" id="CHEBI:30413"/>
        </ligand>
        <ligandPart>
            <name>Fe</name>
            <dbReference type="ChEBI" id="CHEBI:18248"/>
        </ligandPart>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001971"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010617"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR602403-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU000461"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2434345.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="212" mass="22416" checksum="AE224B860A5062FE" modified="2021-09-29" version="1">MVEARISSELEGAGLLAAPGRPEPRQLSWGDLGGLKYLNAVIHESMRLMPPASGGTVRAVPRDTELAGYTVAKGAMLWIPFYAMQRSERVWGPDAAEFRPERWLSGGGGGTAGVAAGVGVGAAEEDDIVRAADAQAARGFLPFSEGPRSCVGQSLALLELRTALALLCGRFRFRLADDMGGVQGAVSEARQHITLKPGDRGLLMHAIPRMPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="4" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TB83</accession>
    <name>A0A835TB83_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_010357</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440477.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TB83"/>
    <dbReference type="OrthoDB" id="10561380at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2440477.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="97" mass="9713" checksum="022533F21AC50DDA" modified="2021-09-29" version="1">MASTATLKDVRKLADEVSALGLPQQDIEPRTLLRPADMRRRGVLPAAAAAAAAGSAAIASESGGFGGNAAYAARLDAVAPSGQSLGRLAAQLRQSLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TB95</accession>
    <name>A0A835TB95_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011990</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000054">
        <property type="protein sequence ID" value="KAG2434991.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TB95"/>
    <dbReference type="OrthoDB" id="547933at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="2">
        <location>
            <begin position="491"/>
            <end position="1060"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="453"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="680"/>
            <end position="701"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="864"/>
            <end position="909"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="990"/>
            <end position="1010"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1066"/>
            <end position="1112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="466"/>
            <end position="476"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="864"/>
            <end position="874"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="875"/>
            <end position="884"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="996"/>
            <end position="1007"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1075"/>
            <end position="1098"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2434991.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1112" mass="110435" checksum="DEA53458E5B52A15" modified="2021-09-29" version="1">MISGELSGAPVSGPRRGTSNGFPQPSFLCGSADGEGLPLGRSASSCAPVSTCPSASPHDLQQGQQEPQPQQLITALQLAAGCTTAASLRTMATHSSTAAGPCCCNNALSADTCMPPTTMPPPPSMTMTEQRYMKEVLGPSGGRSDTTSDTASCQQQQLTQQLRQSQAPAAQEVALLLLAAAGTTSPIAAAWAGARAASLRCPPPALQQQEAAALLGGAQPVAVVLQSQPPAAAAEGPVTAAPSASRPPQLAAQVRRLEVSGDGGRTPAAAAPAACTAAAAVHSSSTSSTDAVLAAAAPPSPPRGRALDRLIALSGLPLARATTLPAGFTPLPSEMRSGGLLLLPSPTSHRPTAPAVVLAAAAADTADTQLPPPPTGAAHVCPAGSSTGGGGGAAACAAAGGGSFADNPATSSCQQLPRRPLDAGCVDQLAPQSPAAGADAAKVEVEVQETELAEAEEAKEAQVQEADAEEVQEAEEVGSPLELLRDVGGLLTQLAPTPPGALGTTWQGTWCGRAVAVKLVCCSAWGGPNAPLLRAACRAARAVQHPNLVPVYAVRVAALDTRAFAMLDPPPRVGAGWAASSAGRTTGRLQRFLAAPAAPLPPPLPVDTTGGCCSYKPTCDPDSAAVASPAAPPPTPPPLVTVRNAAFLNAASEPAAGAPAGATSLLAGAAAAAGLPAAPAAATGRAGSGGDDAASRAPAGPRSLTVYPAGDLLPPAAPRPAEQAAALRALSCLRLQPGGCVVAVIRELCDMGNLCVLACAPETPFRASRTWPLHVARRALLRTAREIAAGLAALHAAGVPHGALTPTNVLLSSSSAADRRGFTARVSEPCSPGLSTTAGNALAALGPAMTFMAPELLVTAATTTTTTTTTGGSPAPAPPAPPPAGALSAGDGANSTNGDPSRLHHHHHCAQHRQHHHCASPPVHECFAMAAVGASADGRGVSAAEQAAALAAGCAADVYSYGMLLYLMAAGEMPFAGEHLVPVLMAVSTEGRRPHWPPPPPPPPPPAAAAAAAAAAAPAVAGGGSLGQHAALQPLYAQCVAAEPGLRPTMEQVLAQLVALEAQLKAAKRATGRRLPPPQRQPQPQQPPLPPPPPPPPRSTAVVAAAVPRADL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TCY5</accession>
    <name>A0A835TCY5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPIase cyclophilin-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009537</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000032">
        <property type="protein sequence ID" value="KAG2443124.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TCY5"/>
    <dbReference type="OrthoDB" id="408413at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.100.10">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029000">
        <property type="entry name" value="Cyclophilin-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002130">
        <property type="entry name" value="Cyclophilin-type_PPIase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044233">
        <property type="entry name" value="CYP23-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47511">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47511:SF1">
        <property type="entry name" value="PEPTIDYL-PROLYL CIS-TRANS ISOMERASE CYP23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00160">
        <property type="entry name" value="Pro_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50891">
        <property type="entry name" value="Cyclophilin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50072">
        <property type="entry name" value="CSA_PPIASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032439326" description="PPIase cyclophilin-type domain-containing protein" evidence="1">
        <location>
            <begin position="21"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="domain" description="PPIase cyclophilin-type" evidence="2">
        <location>
            <begin position="30"/>
            <end position="185"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50072"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2443124.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="236" mass="26280" checksum="4B433800515935D8" modified="2021-09-29" version="1">MARKVFALLFLGAALGSAWAEEVIPVMSDERVVFQTDYGDITFGFWPEVAPVTTAHIFKLVRLGCYTSNHFFRVDKGFVAQTSDVVGGRSLPMNAEQEAEAGKTVPLEVVQGVKHHAGVLSMGRYDDPNSGASSFSVLLGDAPHLDMVYTAFAKVTEGMETLRKMEELPTKREGIFVMPLKRITIQATYWYRINRPEPALTLPDAKVCEDDLHELTLRFASQAEELQRVRKKCLPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TFA3</accession>
    <name>A0A835TFA3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_009441</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000032">
        <property type="protein sequence ID" value="KAG2443026.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TFA3"/>
    <dbReference type="OrthoDB" id="38730at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044:SF3">
        <property type="entry name" value="KETOPANTOATE REDUCTASE N-TERMINAL DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34044">
        <property type="entry name" value="NUCLEAR PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2443026.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="337" mass="34610" checksum="C8D97F8B4733B839" modified="2021-09-29" version="1">MGSIGLTHAVRRRSLLLLLRQGPIYVCTTNDALDWVLEVTPRSRRRDLVLFQNGWLAPWLGHNSLWLGGAGEAAAAKDLGAAAADVAEGKAAARKAAGVGAVTGPTTTATGAGAGAAPGVAGEGDEVTLVALYMAAGPDGTAKDGLRTVASGRWAHHVSRTLARGGVRCRAVRGADMYVAVVEKLLWACVFWMLSSALGGMKVGDIVEEHRDDVAALTAELLPPLCRQLRAMAAVPAAAVAVAAGEEEDSAGREAAGAAAAAAATLEAGTERVVAALVEYSLSIAGAVPSRDMAVAEFRWRNGALLDMGPTPRHVAWLRRAGVPQELLQAHGVAAGV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TGB2</accession>
    <name>A0A835TGB2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Methenyltetrahydrofolate synthase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_009295</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443222.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TGB2"/>
    <dbReference type="OrthoDB" id="433414at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10420:FF:000001">
        <property type="entry name" value="Methenyltetrahydrofolate synthase domain-containing protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10420">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002698">
        <property type="entry name" value="FTHF_cligase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024185">
        <property type="entry name" value="FTHF_cligase-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037171">
        <property type="entry name" value="NagB/RpiA_transferase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13017">
        <property type="entry name" value="5-FORMYLTETRAHYDROFOLATE CYCLO-LIGASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13017:SF0">
        <property type="entry name" value="METHENYLTETRAHYDROFOLATE SYNTHASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01812">
        <property type="entry name" value="5-FTHF_cyc-lig"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF100950">
        <property type="entry name" value="NagB/RpiA/CoA transferase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0694">RNA-binding</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="291"/>
            <end position="363"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="315"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="338"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="354"/>
            <end position="363"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00015518"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2443222.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="363" mass="38718" checksum="5336689786E70498" modified="2021-09-29" version="1">MASPDAGRAPTGGAFDAESYNAERLKLDEQLARDASAEAAAPGSVAGAWKWAIRKKIWDYMEENDIARFPRPVHHRIPNFVNADVAAERLSDLPEFVNAQCIKVNPDTPQKMVRNLVLTRNKTLLTPQPRLRTGFFSRLTSASFPPQDLNEACTSAGVAKYGEPLSLDTPVKVDLIVVGSSCVDPASGARLGKGEGFAELEYGILRYMGAIDEHTLVVTTVHDCQVLEPGAIDVSKMLEHDVPVDIIVTPTRVIRTNTNLPKPPGILWHKLSPQKLGQIRILQQLKQRIERETGTKLPSGPDETLPPLAARGKRQQGGGGGSGGGGRGGRNRPRGNRGGRGEGGGGGGGGGGRGRGERAPQAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TKH8</accession>
    <name>A0A835TKH8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009688</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000033">
        <property type="protein sequence ID" value="KAG2442204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34491">
        <property type="entry name" value="A-TYPE INCLUSION PROTEIN, PUTATIVE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34491:SF74">
        <property type="entry name" value="DUF4456 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="126"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="387"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="493"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="557"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="677"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="813"/>
            <end position="843"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="998"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1195"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1232"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1331"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1391"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1486"/>
            <end position="1530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1661"/>
            <end position="1704"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1847"/>
            <end position="1916"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2044"/>
            <end position="2066"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2145"/>
            <end position="2187"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2252"/>
            <end position="2284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2374"/>
            <end position="2429"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2467"/>
            <end position="2618"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2751"/>
            <end position="2813"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2841"/>
            <end position="2876"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3046"/>
            <end position="3108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3214"/>
            <end position="3265"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3282"/>
            <end position="3310"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3324"/>
            <end position="3355"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3562"/>
            <end position="3663"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="3724"/>
            <end position="3770"/>
        </location>
    </feature>
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        <location>
            <begin position="3820"/>
            <end position="3883"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="2291"/>
            <end position="2328"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="140"/>
            <end position="149"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="388"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="501"/>
            <end position="511"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="558"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="586"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="679"/>
            <end position="698"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="816"/>
            <end position="832"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="833"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1002"/>
            <end position="1016"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1037"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1157"/>
            <end position="1171"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1177"/>
            <end position="1187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1257"/>
            <end position="1268"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1269"/>
            <end position="1281"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1341"/>
            <end position="1353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1391"/>
            <end position="1405"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1426"/>
            <end position="1442"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1486"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1502"/>
            <end position="1512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1661"/>
            <end position="1672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1692"/>
            <end position="1702"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1865"/>
            <end position="1885"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1900"/>
            <end position="1913"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2161"/>
            <end position="2181"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="2254"/>
            <end position="2266"/>
        </location>
    </feature>
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        <location>
            <begin position="2267"/>
            <end position="2284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2380"/>
            <end position="2395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="2396"/>
            <end position="2410"/>
        </location>
    </feature>
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        <location>
            <begin position="2467"/>
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    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2498"/>
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            <begin position="2530"/>
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            <begin position="2551"/>
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            <begin position="2575"/>
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        <location>
            <begin position="2779"/>
            <end position="2788"/>
        </location>
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        <location>
            <begin position="2789"/>
            <end position="2802"/>
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        <location>
            <begin position="2854"/>
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        <location>
            <begin position="2867"/>
            <end position="2876"/>
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    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="3047"/>
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        <location>
            <begin position="3070"/>
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        <location>
            <begin position="3220"/>
            <end position="3243"/>
        </location>
    </feature>
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        <location>
            <begin position="3256"/>
            <end position="3265"/>
        </location>
    </feature>
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        <location>
            <begin position="3293"/>
            <end position="3310"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3326"/>
            <end position="3338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="3566"/>
            <end position="3586"/>
        </location>
    </feature>
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        <location>
            <begin position="3587"/>
            <end position="3607"/>
        </location>
    </feature>
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        <location>
            <begin position="3627"/>
            <end position="3648"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="3727"/>
            <end position="3746"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="3820"/>
            <end position="3838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="3846"/>
            <end position="3875"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2442204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="3915" mass="392379" checksum="FEA14FBF96A29977" modified="2021-09-29" version="1">MMASKQAPDGAGATNGGLRLCAAPSQLLLAGSTAEHHQCSSQLAALQQRRLALAAAGLTSPAAVASCSSRRHLHSQRSQLSALRASARAGSSGYRPHLRAAATSALTAAGHAVAAFNRRAAAEAAANAASAPQTQSTESSRADNHEDAVGDKYQKARLAARLNYREELTALAGAVPNYDGLTVLAAALKQQQECYKERYKLAKELAQGPQELMSKLFAMESASEQATDKGQAAAALRAQHMAVMQQALKGMRSGPAAAEAMGAAQGRLEGAFGRLNAWAAALDPFGVAARLRAAAAALAAATAAAAAAATAAAAAGGGTVAEDPRELEGRVARALGVGGDLRDVSGRDASSRADHAALCMVVALDALWACGSSDRGPELLAAARRRGGGGGGGFGDSDDSGGGGGFSGGGGGGGGGDSSSSGVDAEWLDGLLLGGVAVVEALAAWHLALADAEEAAYITPTCAGAGAGAGAGAGAGAGAGAGAGAGAGLVSGAAAGDARPVPLPPPPPPPKSQTATMTHCELVSLFFIVAQWQPNIHILKCKFEDLMGAMWRWRQGRRQQQQQQQQPQYGCLARTPGTGSPAGGSRRAEADTTPDERGVLYTMGWGSLPVLARLVAAVAVPALRAPLWPPETPDGAKSGAELEVEQRVAAAGPSPFAADASTAAAAAVMGAAAAAAEGTAGGGGGGGGGVGSSGGGVVADGADEEDVADVQPPPVDVRRNLCAVLLQLHCHVAEQAAEVALQAAAAPAALTAAAPAGCSSVPAAAEADAKSAGEAGAATLDPVRAFWRAYEAAARDFATAALMQAVMDLEEEPSSGAAAAPHAGAGTAAKTADGGGGGGGRQAAGLGKVDDCAAAPPSAQAAASAKAAAAMAAVDAMAAAARADGSAAADVAARGAGLLASRRRLWRQQYAATLRGLGEEGVCGAPSGAPSGAFSSGAGGASGGGGGGASGAGGITGRQAAATFRLMAAGRRRNLVATEGLRQVMAAAATSLPAALRRQLSPPSPSPLLAPAPAPPWLTGAAAASGGGDSSASCITGPPPPPPPPPPPPPPQPQLVALRSGEWPGRGAREALARALLMADTAQAPTPWFLVEGGEALRQLAAHWAALELLHFHTRNLWWGMLHFQHDQTCQQGLEGAGEAGGTAACSAAAAAAGGGAARAGGLPAHGGPGGNEDQDRDPQQDGKEEEAVAAEEEEAAKEACWQALWEKSRFVGAYLHMQDVRLRAARWLLRGPPPRRQRQQRPAQGREAAGRTRGEQQQQQQQQQQQQPKNSSALRQTNAQAHHDPTFNHPELRAQVQDARGQEEQDKGPQLRPRPLAALGLARLALQVAPSGDGEGGSSTAGSSCINGSSTSKGMSLQVRFVPLLLTAEEQTAYLEADALANLMGGGGSSGGGSNGGGGSGGCSSGPQPPDSDDDDDREGGEGGEAAVAPSQSASTAAAAAGATATASAACGRRQQWRRRQQQLAEPAAECGPSEVIAFAIITSSSTGSSSSSSHQLDIRLPPPPAPPPLPTGDKGGGSSAAHERAREEERASLADSLVCALDGAGFARLWPHTAAATATATAAATATATAAAAAGGSAGGGGGQGCALQLLFEALALARARLLSAGRDFVVVGVPEETPLIEHEGSAAGALSATSATAALMHRHGLGAAIPIAPGSCGGGGGGGGGGGGSGRHRQQRLQHPQLLSPPPGQGAGAGDGAGGRQAWEGAWGAARRAVACQSVCRLLGLLGPADDVHHLIAVQNLVPKLQQLGKQREEVMARVHSSRAAAARGGSGGSGGARGGLAAAVAERAERAREAEMEAAARGMAELRQLGVMEARLQRGLAERMVGLLGNEESRRELCGSRWLRQPQPQPQPQPQPEELEGQQQGFQREGRAAEGPAGGRRAQARGRSRDGRAGRTAGGGESGESGEGGAGEKRACPLPLLLLLAGSTAEHHQCSSQLAALQQRRLALAAAGLTSPAAVASCSSRRHLHSQRSQLSALRASARAGSSGYRPHLRAAATSALTAAGHAVAAFNRRAAAEAEAAAIKADSALEGAAAAAATVHPSSGAAKGPDALLPSSDDGTSMTKVEKQLRVEERQRMRQELQAQFGQVGSWDALPHLAAYVSGLAPRVSAGHNVLKQQKFQVMLAEKALERAAEGPAPAAAAAAAASGAGGGRGSGRTQQHQQQHQQQHQQQGQPQDVGGESLQQLQRRLEAARAQELEAQAGLLPLLARAVAACELLSAWIQELAPLRVSGQLLAQERAWKAAQQAAAGGGGGGGGGGSPAGAAATASSGSGMGAPAADGAQTALIMQQQQEQEQQQEQEQQQEQEQQQQQQEQQQQQQQQRVLVSISALVTLWGGCSAAVAPSEEAREALMQQAAALAAALVLEHDDDDEAEQQQQQQQPQQPQQQLGQEEEEEEEEEEEEKEEGGGGPAGGSSADPPEPAPTYPELRCLAFLLSMWHARLQPIHCGLAELERVVTAKGSVSAAPATSTSAVRYGQRCEQGDQQLRRDHQQQQQGQGQQQQGQQGQGQQQQGQQGQGQEQQGQGQGQGQGQGQGQGQGQGQGQGQEQEQQGQEQQGQEQGQGQGQGQGQEQEQQQQQQQQQQQPGKQAEASAVPAGGAAAAGGGPPVAAAAPPADLAPAALERLRDLCDAGPLRSLARLAAALTVPALRAAPRRDDDDGTEAAAAAAAAAAPAGQVAAAANPFIAAAAAAAAAVGGSLGGQEGDRQPPPLECQHEACGLLFALHLQTLVSVLLVVLGLVTGTDERQGGGGVGGDDEDDAGDAGAGSQRSSSGGSGRGGGGASSSSSSSSSSSSSAGAGGGEPSRKSSAEAAYEAAMAAAREALLLDVAAGGGNGECEVTSSSRRRSSSSSGASSSSSGSSSGGGSGSGGGSGVLVVTARSVQAAYAAASRCLAPRLAARHLQKGWDDEGALEDALAAAAAVAVAGAAGRAGDCGGGGGGGGGGGATAAAAAAAVAAAMDAYEAQAEAAVVQSLQQSLEAWRVAAAEVAAAAPPDERTVNLGRLEMQLVAARVRNRALTLAARLGAAAALRQVPEALGCSSQGGGGGGGGSGGGSGGGSGGARGAAAAERGLAGPREEKKPEAAAQGQPPPQQQQQPQQPLVALRSGEWPGRGAREALARALLRADTAQAPTPWFLVEGGEALRQLAAHWALLDSLREDGGALCSGGGGGGAELQRRLAAGVKAGLEWLKQATTAAATDWVRMRQRAGVQRPAAGGGEAAAAGGGGAQAEAEAGGGEVPLVQGRQRGPGQRKDGREEQQVRQLAALGLARLGLQVAPWGDGEGGSSTTGSSSSGGSSTSKGSSASLQVRFVPLLLTDRWQQQQQQQQQQQQQPYPSGSMQRGGGEARDCVRSLEPAPTAATAAATAAATAAATAAAGFAAAAAASVCAPAAFVAYRDALLLPVLVVERPRGDSTEAWAAERAAAAAALHSRLEQDGLCVLLPDKELLPPPAAGSGGGGGSGGGGGGSCRPAGGCPLLLTFEAIAKVRAAWLERGRDCVVCVLMDRDTLMQQQHQQHHHHQQQQQQQQQHAGADCLVSAVSALSGAAYRVAQALDLGRHPLQPPQPPQPLQPLQPPQPPQQAWPQAPRTAAAAAAAGGAATTEGGGGRGGHVTSDKGAPGPRGRQQQQQQQQGQQQGQQQEQQRQYHHQQDVPGGSSCPGQPEWEFAWSLVRRVAVCQGVCERLGLLGPRDDQWILSDAEQVEEQLNRAFKEHQELMRDMASGSSSGTTGSSSSSSSSSSGAVRGSNAPRGMAARVAARAQRSREEQQQLEARRLALVGRIVGLGRELESRLPGLLGCEDGGRLLCGSRWLHGGGGGGGEAAGKAGGAVGGGSSSSSSSSSGGGGKSKGGGGSPAGRQGGPQVGSGGGGPQEPWRPPPLSLLVVECDAADPRVLLPPLPVRQALGLGLEP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TPT9</accession>
    <name>A0A835TPT9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_009520</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000032">
        <property type="protein sequence ID" value="KAG2443106.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TPT9"/>
    <dbReference type="OrthoDB" id="531835at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="11"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="21"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="48"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="60"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="113"/>
            <end position="133"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2443106.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="186" mass="18745" checksum="8E7F0C60E6484F06" modified="2021-09-29" version="1">MQQQQQEPQQQGGGGGGRGPGIWPFGGPRAAPRRGRDVKDAFEAMQQGGSGCGGGGQRRPLREELADQGPRGDGDGDQPNNHPHHDYHHPLNSPAAVPCSGGQGIADDRKQQQGGGSSGSNGSSGGGGGGGGSSSADADDEARVAAARRRGGDSWARRVSAAFTAKAGDGKDEEGEWVGAVGGWVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TPU9</accession>
    <name>A0A835TPU9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_009484</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000032">
        <property type="protein sequence ID" value="KAG2443070.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TPU9"/>
    <dbReference type="OrthoDB" id="546319at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.10">
        <property type="entry name" value="Tetratricopeptide repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011990">
        <property type="entry name" value="TPR-like_helical_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81901">
        <property type="entry name" value="HCP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="171"/>
            <end position="248"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="287"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="483"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="576"/>
            <end position="595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="105"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="117"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="171"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="192"/>
            <end position="203"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="229"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="287"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="577"/>
            <end position="592"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2443070.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="812" mass="80749" checksum="0FA30E1DEC2AFBC3" modified="2021-09-29" version="1">MQGGPTFEVALRSCPPAKLVYGHVPTANVNAAASRIAGHAVKGDACLLLSPTGAMAGTGGTSGGASSSSRQLLQLPPPDLLLDALLGGTRLAQQLLANPRQQGPSSPPATPPPQSPAPHQQPNTAAPASAAAAAPAVASPGRKQARCPQAAISAILQGRNALASVGAAAASMSGSSGSSSQWTGGAGGGAGASAAPSVSAALGRAPSWEPPLAPPCKSARNSLESPPHPPHHQHHQLHPPPHRPAHAPHSLVSALAAAVASGDGIARPASPGVSCLARQLAAGSLLGGGGGSSPAHGGHGALSQEAAATASGGSYPQPHKRRHSVDSVEASDACMSPSDAATAATAAAAVAVQAACMELDAAGPVAAVCCEPAGPEASPVAVAAKARRSLQEAAVLQGPGLGAKAAQQQQQEQVEAAPAEQQQAGLEVDVPWQELPCDVVAYVATQLPQQASQAVAMSGVCRGWRVALLGNLPALRRITFNLDPTNHLRGSSSSSSKPTSITPTTGSSGGGGVGAVACAVGLRRRSAARDAAAASADATGRGEEEQAAMAVALSRQYGVGSFVLPCAHTAAGGLEGMEEHTQEPEPEAKEPVVPRAAARRPPALLLEAARGASNPSAQLVMAQLLEGSGDADGSLRWWRKLAIAGDVMGVFKLGMACYDGSHGMQSDPEAAHMWLSRAVRHILQVDSLSAIQLDEQHGSGGGAGSGGGGAGGGAPAGAVGAAGGTGAGGAGGQPRVSLRMRRKLAALDPTLLRMLGWSSIVLGYLEFDGVAGRSVWGMGDRSEAVRLFRLAEGCGCNEAAAVLGWLYNTGQY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TQ35</accession>
    <name>A0A835TQ35_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_009281</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552208at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051345">
        <property type="entry name" value="Importin_beta-like_NTR"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363:SF54">
        <property type="entry name" value="NUCLEAR TRANSPORT RECEPTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12363">
        <property type="entry name" value="TRANSPORTIN 3 AND IMPORTIN 13"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="315"/>
            <end position="405"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="734"/>
            <end position="756"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="787"/>
            <end position="842"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1014"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1108"/>
            <end position="1128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1269"/>
            <end position="1290"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="1421"/>
            <end position="1452"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="320"/>
            <end position="338"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="361"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="383"/>
            <end position="395"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="792"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1030"/>
            <end position="1052"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1108"/>
            <end position="1118"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2443205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2078" mass="207789" checksum="072A5562F745F26A" modified="2021-09-29" version="1">MTEAQLSLVRSAVNALYVAQDGATRKAADHWLQNFRNSAGAWQLCLALLARPGLADYEYHFAAHSLRLACSKDILDPNVLQSLAAQVASLLLTSVNAGAWPVASQLSSALAALAVRATCWEEEALVPHLLSLLAPQVATAMLADLALGNAALSGAPGGVGGAGSPVVLAAVAAEAGAVYALLQVVSNLPEACTSRAVCAHAQRKAVVAAALASDAMVAPLLRAAVVGSRNLGAGGATGAPAGAASSGAALRRAGLQLLRAWAEQLGTAPRALEHEVELVSCLYESLVTSDTAALAAECLCGLINNCVPHRARDGDGGENSLSGYHSDSSSSSSMLLLSDAPPGGGAPLGFSGMRRGGTTGTFGTTGSTTTSNWSEAGFRRSRGMGGGPGGAGGPSRGSSGAHQRNVSPLAAAAAAAAGHASGTGMLGMAGLAAGAGLSVQGVLALSPERQLAATLLLQRLLDGLQGLLQSAAVVYRQQHQAGLISPPPGVAPDSEVAFWCLWTDGAVLQAICSVLCAAASAVLPPALRGDSALQGRFAVLWPQLMALLGHSNPEVALACVSFWQDTYLAQLLQSCAPPPAAAAPQTALQAHLAAQQAAQRLAMLQGHLPLLGQLLAGLVSRAALGTEAAAAATADARDLPEEVRMVRRELGATMRDLVDLVGLGHVAAFLERMITEHASQLTVAATTAASSASGSTAPSTVHSAAHSIANSAANSNANSIEVVPVGPGEEIGGTGGAGGIDPATAVAGGKPGAPPARGPGGLVVWTRLESSLYAANVALCSGGGLAGAIKTPNRPNNRLPPNEGSTGSTGSTSTLASPPGPPAAHQPQGHPHPQSHHGPRAAAAVAVNGPPVDDAHVASIMNTAAAAVVHPASSLKLAGTALTLVGGMAPWFALHPEALARPLDAVRAALRSPDEKLARNAATAMNRLCVHRGCAALLLGRYSGWVASLLELLPGPDVTLRHKPAPGVDMTSRELLIASLMRLACNGAAFGTTTNTTTTSADAITVADASATGAGTDADSNGNVAMGEQPAASDGAGAAAPSSAAGEASGDELTPRELLRRLLAPRMMAAIEELDKLAELVRDNTSTGALPTHLQHWRGSRRQLQVQQQQHHMQQLQQRHGHPPLPPPPPPPALPLGFPFTPADAVNARAPLCRVTAPVELQRLGAVATVAAQRVGGLASMLMFIPAAGQVQDMGGGGHSRVIRNAHEALLATAPPDGDASAVVVASLVVQMVRTVWPHLIGCLQAAGPTGETAAGMKDGDGAVADGVKAADAAATSDEHKNQDQEQQAAEQRAVLLETLEGAHLLPAACSLLQGSLLVAAAAGHVLSTGAADLLASANAVLGVSHGAPPIPPTEQQVAAMQWPANLDWPEAGPGTASGGAGRLAAAAIGLHQQQQRQMLAQAQGPPLCVLQLVLGCMPVCNDLLSLKQTAQRQQNDAQQQQQQQLQQLQQQLQGLQPLQPLQQQQQQQQQVAMDAQSMQQLMEGSAVAERCVQEACTVAKEACLSLLAPRSLPGRSTTSTSLAPDPERMLAVLPVLQSLLLNAPQGIAASRDLLEAMVATAVSCMHCSDPEACRSLLDWTTLLLGTTGFVPQLGSNGPSAASTVLAATAAVSSTAGTPGGAGPQAAAGTGAAVGVKGPGGAGGGGRGGSGSGLSALIVRCRSSPMYESAYAEIGSQLDLPIPCAPPNSIGLVYSQSVAESGVLGPAAAAAAAAAAANAAAARAAGASAVASAPSAANSSSPDLASLQAQLQAQAQMQAQMQIQAQLQAQATAAAQAQALGLQGLGGAGGIPALGMLGGAGAAGMMGLGGMGGMGGMGGMGGLGGLGQQQQQQMLVMQGGRLTSINVNTLGTNMNFNNMNAMGMNAMGGAAGGLNVNVMDMLMGAGGGMGMGVGMGMGGRPMGHMLGIAAAPPPPAPAPPPLPQPVVGCLGSVLVLSLMVAASGGMPPDLMLPISNCLHSGWQAMGGARFRTWLRSAAMELSAPPGGHNAAVAAFTGGMGGMSGMGGMGGMAGGMGGGMGGGGPFGMGGGLPWARLKSDLLALSLTELWGDDCERDVMKFKRALKALCGGKKKGIGPY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TQ41</accession>
    <name>A0A835TQ41_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Plastocyanin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_009787</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000034">
        <property type="protein sequence ID" value="KAG2441995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TQ41"/>
    <dbReference type="OrthoDB" id="262547at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.420">
        <property type="entry name" value="Cupredoxins - blue copper proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008972">
        <property type="entry name" value="Cupredoxin"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2441995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="131" mass="14312" checksum="3329D290E2897A5C" modified="2021-09-29" version="1">MFHCHNLMHEDFEMMRSFSVVPTPGSRTAATALPLQAQPTIVQNLNVVYDLYDDPLYPPAAARPSAGLTPLRVPGAATTAALSFPITNALYRIYYPNGSPNVSPLLADPALNPWIVKICQPQGAQQRQQPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VQQ1</accession>
    <name>A0A835VQQ1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015549</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000415">
        <property type="protein sequence ID" value="KAG2421994.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VQQ1"/>
    <dbReference type="OrthoDB" id="547029at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="48"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="346"/>
            <end position="369"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="52"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="72"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="1"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2421994.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="450" mass="45564" checksum="B212571016C6A628" modified="2021-09-29" version="1" fragment="single">EEREEEEREGVGEAEAEVGPRHPSAAAELLSALRPRWDPTRAAAEAAELAAAGGGAGGGNSWVAGGSGNGGSSSQQQQPQPPWELAAAAPSVTLDALVSAIKHELPQQQGALQSLKTQHAVVATRLQWARQREADAELTRATSSHGRAAAGGAAGLRAAAVARGGAAVRARSQGLRSMCESLISDMLDLTMCRIEARPGAAAVAAEVAAWRAARPGALAGVSRHVAEAVMWEVVDEMVAEAYDELHHLAAVADGFAFDLLVEAVAFSQAKYQFGGGGGGGAGGWAGAGGGGRDGVRARLRDAEARREAHVAHSIAARRAATQSRNAAKAAHIAAASVMAGNSASGAAAVAGEGDGGGGGEDDDGGGGGGGYDDGAYAAYVQQLAAASKPIKVGGFNILLRQNPHVFYFQRRGVPQPPHPPDVVAVPHADLPARVRHYLRGAAGPPPPPPA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2023-02-22" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VR27</accession>
    <name>A0A835VR27_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_015396</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000196">
        <property type="protein sequence ID" value="KAG2422713.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VR27"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2422713.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="204" mass="18850" checksum="A8E1A9CD8CEB4AF9" modified="2021-09-29" version="1">MRAGGGSGSSSGLLLVLRSGSSRSSSSLSGSLSGSLLSGSLLRGSLLSGSLLSGSLLSGSLSGSLLGGSGLSGSVRCGSSCGLSGRPPLTLAAAGAAAEALTALAASTGGRVGGRRGMVAAGVYWQPPLTLAAAGAAAEALTALAASTGGHVGGRRGMVAAGVCWQPPLTLAAAGAAAEALTALAASTGGRVGGRRGMVAAGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VRS3</accession>
    <name>A0A835VRS3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015017</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000116">
        <property type="protein sequence ID" value="KAG2425410.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VRS3"/>
    <dbReference type="OrthoDB" id="196393at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="40"/>
            <end position="60"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="74"/>
            <end position="319"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="130"/>
            <end position="146"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="147"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="157"/>
            <end position="189"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="190"/>
            <end position="201"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="210"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="222"/>
            <end position="251"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="260"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2425410.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="319" mass="28919" checksum="79A05869D0169CD5" modified="2021-09-29" version="1">MEPPLRRAQVPAELGEKAVRIMAASSGGAVRGQELANRWGKVQSPPDWPPGSGRPAAGHVRGAAAAAAAVDRLPGSGGGMGRLSAGGGGGFGAEQDYEVDPNDVGNPFARRPPGPAASVLDSVRRPPSGSGMGGGGGAFGAGGRPGSSGARPASTGRAGGRLGSAAGGGLSPIGAGSGAGGGGGSGHGIAGVSSSSSSSSRSPREGGPGRPASAGRRPSSSSGGGGGGGGMMAGRGGGQHGVLAGGLGVSGVGLNPAGLRGSGGGGGGGGGGYAGSGGGGLRGSAGMGTAPPGGPPGGAAGGSAGEPKPTSSGFRPIYD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VU54</accession>
    <name>A0A835VU54_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Cation-transporting ATPase</fullName>
            <ecNumber evidence="13">7.2.2.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="17" type="ORF">HYH02_014997</name>
    </gene>
    <organism evidence="17 18">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="17" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="17">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12 13">
            <text>ATP + H2O = ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:13065"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 13">Membrane</location>
            <topology evidence="1 13">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 13">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type V subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="17">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.-" evidence="13"/>
    <dbReference type="EMBL" id="JAEHOD010000114">
        <property type="protein sequence ID" value="KAG2425624.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="48943at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019829">
        <property type="term" value="F:ATPase-coupled monoatomic cation transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0140358">
        <property type="term" value="F:P-type transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1110.10:FF:000023">
        <property type="entry name" value="Cation-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006544">
        <property type="entry name" value="P-type_TPase_V"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047819">
        <property type="entry name" value="P5A-ATPase_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630:SF8">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45630">
        <property type="entry name" value="CATION-TRANSPORTING ATPASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12409">
        <property type="entry name" value="P5-ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 13" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 13" id="KW-0460">Magnesium</keyword>
    <keyword evidence="11 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 13" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6 13" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="18" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9 13" id="KW-1278">Translocase</keyword>
    <keyword evidence="4 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="10 13" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="218"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="387"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="423"/>
            <end position="444"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1112"/>
            <end position="1134"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1140"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1180"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1226"/>
            <end position="1244"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1256"/>
            <end position="1275"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="1305"/>
            <end position="1327"/>
        </location>
    </feature>
    <feature type="domain" description="P5B-type ATPase N-terminal" evidence="16">
        <location>
            <begin position="2"/>
            <end position="106"/>
        </location>
    </feature>
    <feature type="domain" description="P-type ATPase A" evidence="15">
        <location>
            <begin position="254"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="556"/>
            <end position="584"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="795"/>
            <end position="839"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="556"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="819"/>
            <end position="832"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006000"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049360"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="RuleBase" id="RU362082"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="Pfam" id="PF00122"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="16">
        <source>
            <dbReference type="Pfam" id="PF12409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="EMBL" id="KAG2425624.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="18">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1370" mass="144617" checksum="57AA753F79EE278C" modified="2021-09-29" version="1">MVLYYFVGLMTAGFSFLMCKWSPRVNIFLSLSPCPLRDAQYVRIRLADGRVDLEKVQEVAMAEPQYDSQPTLAADEEEGAGRGGLLDWQVQRTHKLLEYRCTRYFYVDGVAAAAAAVAGGPVPGPGGATFTPVPAMPKGFNEQLRAAAVTLAATGHAAAVEEAQDWDLGERQLRYGTNEMAIPVKSIPMLIFDEMWHPFYVFQYFSILIWIVGDAYYSYAVCIAVITWFSIISAAYEAHQNMKRLAEIAHFECQVDVVRGGEVVRLPSSVLVPGDLVVVAPGTLPCDLVLLRGECILDENMLTGESVPVRKVAYNAVADGLGYQPDKCPGCTLFGGTVVAQARAQRAQKPLAMVCRTRFYSAKGQLLRSILFPREHEESFISDSLRFICVMLAACMGLYIWAAVVLAQVGASPDRIVVRFFDMITIAVPPALPACLTIATVFSIGRLRKKGIYVTSPDRITLAGQLDVICFDKTGTLTEQGLDLQGIVPVVQGRLHNMVGDMSLLPTQLVELLASCHGLARMGESLVGDPLDQKLFMATHWDLIDERPSLDGAYGGAYGGSGGGSPPQTDIDGNVEGPGAGAAEAAQAAAEATGTGGGVQTYVRPPGAVHAYAIVKRFEFSAALQRNLVVVRAPDNSVAVFAKGSPEAIRALADPGSIPADFDQLLGELTREGLRVLALAAGDASTVPETALLGWTQAETEANVGLKLVGLAVMANPLRPDTADVISRLQHASIRTVMVTGDHLRTAVSVAHKCNILPEQRPILLIDAADLPAPAVTTSQPAPLALLAATAPAAAAAQSPEPTPHSTPLPVLRPAHSYGEASGPGPAGEPTPLGDPSIAYPNWNGALLTEEAKAAEEAERRAAAVVGTPYHHGASAVDGSGAGSSSGGGGGGFLGDCSPASQHAHVVVQAQYPGMAAPGGTGDKGVALAVANSGNGHHHQATVTAADAAAAVAGPGLRLSVLDVEGNVTENAGSAAAYGMMARVVTGELECAVTGKGFNWLLASLDAGLLLPVLQRAGVFARMSPDNKRDLMLLLGSGIDGVEGCPHLGLRAGFCGDGANDCGALKAAHVGVSLCEAEASVAAPMTSKAQTIASMITVVAEGRCTLMATYQIFQFIIAYALVQAFETNLMYTYALNLGNYQYLIEDLFFTTVLAALMGFTEPRNKLSRSRPLTRVMSPPLMISTVLQCVVIVVFQLLSLKLLQSQPTYVRFRGGPELHDTVAPENTTTYIVALAQFVVLALVFNKGMPHRSPLWNNLWLVAALVIQTAFVIYSLFSTDAFNLNVQQLVDKTSFNGVMDNEFRWKLFGLLVAMGITAFAAEYTSIGIVKLLNWAQGRGGVVGSVRGTKAGASGTKGSVPSTVPGAIRVPAN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VV81</accession>
    <name>A0A835VV81_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">protein-serine/threonine phosphatase</fullName>
            <ecNumber evidence="2">3.1.3.16</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_014813</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="5">
            <text>O-phospho-L-seryl-[protein] + H2O = L-seryl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:20629"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="6">
            <text>O-phospho-L-threonyl-[protein] + H2O = L-threonyl-[protein] + phosphate</text>
            <dbReference type="Rhea" id="RHEA:47004"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="EC" id="3.1.3.16"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.16" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000107">
        <property type="protein sequence ID" value="KAG2426386.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
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    <dbReference type="AlphaFoldDB" id="A0A835VV81"/>
    <dbReference type="OrthoDB" id="10249888at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
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        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
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        <property type="term" value="F:RNA polymerase II CTD heptapeptide repeat phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd17729">
        <property type="entry name" value="BRCT_CTDP1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10190">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
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    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
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    <dbReference type="InterPro" id="IPR001357">
        <property type="entry name" value="BRCT_dom"/>
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    <dbReference type="InterPro" id="IPR036420">
        <property type="entry name" value="BRCT_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039189">
        <property type="entry name" value="Fcp1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004274">
        <property type="entry name" value="FCP1_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
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    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23081">
        <property type="entry name" value="RNA POLYMERASE II CTD PHOSPHATASE"/>
        <property type="match status" value="1"/>
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    <dbReference type="PANTHER" id="PTHR23081:SF36">
        <property type="entry name" value="RNA POLYMERASE II SUBUNIT A C-TERMINAL DOMAIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03031">
        <property type="entry name" value="NIF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12738">
        <property type="entry name" value="PTCB-BRCT"/>
        <property type="match status" value="1"/>
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    <dbReference type="SMART" id="SM00577">
        <property type="entry name" value="CPDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52113">
        <property type="entry name" value="BRCT domain"/>
        <property type="match status" value="1"/>
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    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
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        <property type="entry name" value="BRCT"/>
        <property type="match status" value="1"/>
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    <dbReference type="PROSITE" id="PS50969">
        <property type="entry name" value="FCP1"/>
        <property type="match status" value="1"/>
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    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="FCP1 homology" evidence="10">
        <location>
            <begin position="701"/>
            <end position="879"/>
        </location>
    </feature>
    <feature type="domain" description="BRCT" evidence="9">
        <location>
            <begin position="970"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
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        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
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            <begin position="247"/>
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    <feature type="region of interest" description="Disordered" evidence="8">
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            <begin position="447"/>
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    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="924"/>
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    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="137"/>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="8">
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            <begin position="8"/>
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    <feature type="compositionally biased region" description="Gly residues" evidence="8">
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    <feature type="compositionally biased region" description="Gly residues" evidence="8">
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            <end position="289"/>
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    <feature type="compositionally biased region" description="Low complexity" evidence="8">
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            <begin position="290"/>
            <end position="310"/>
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    <feature type="compositionally biased region" description="Pro residues" evidence="8">
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            <begin position="374"/>
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    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="501"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="539"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="585"/>
            <end position="645"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
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            <dbReference type="ARBA" id="ARBA00013081"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00047761"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00048336"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS50172"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50969"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2426386.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1063" mass="108849" checksum="EF27AE4F7B6C0F54" modified="2021-09-29" version="1">MAGPLASEEGELEDGEVELEGAPEAEESGEASGCEDDAEAAENGTGQETAGAAALKPHGSLPPPPHLQPAGLPLAPSRSGRLQDSHVLGSGMGTSPAPGAKEGGGGGATGGKDDREVEELQALLRDLTRNSSFQDVMRSLETVCRDLKQAIKKLDKLFRRVKRRKGDSIEDYPDCFQYSRRILEGLHTVNKFSQTSAYLAAPATGADAARALFKAAMNYRHDIFNAALKAELEALVRNSKAFKVVLENRRGGPPPAPTPAPGAGGASTPGAPGAGGGTPAPSGLGGEAAAGGARASSSAQQQHSQVAAAGAGAGTGADSKPTGSEQRAEAAGMGARGEEAPPLPSGLEDAGPHPMDTDAQVPPPPPNSHWRSPSPSPGPEGVPPPGPPPPDGWPPASKHTPGSGGGAAGATARSSLQGRAASSLLGAAGGGSAFKLKIVVASTPGDLRAAAAAAATTAGHEAEGDEPPAKRIRGAAEGEAGDLRWSGAPDGAWMKREEGEGGPQGPVLGGGEGGGALPAPPESPVSDAGAAGGGEDAVDTAAGAPGTGAAHIPQPPQLQPSHSQRPGSKSKDGHDDTAGGGGGGSHRERERSGRDKDRDKDRERERDRDKDRDRDRDRDRDRHRSSKDKDKDKERDKDRDKEHGSSHRSSRHRDRDRDAAAHIKSEAAGGGETGPSASAQRLAVAAAGLSDDQAAVVSSCLGRGRLVLVVDLDGVLADSCWDAQLDGPTAAALVRRAAVEAAALPEDRRELFRLPLEGGALWLKLRPGARAFLARAAERYELWARTRQGRPYADAVVELLDPHQQLFGSRVVAAGVLAKRLLTALECRAPIAAVLDTPDAAWMGEPLSGSLLALPPYAYFAVRPCAPGGAVAASGMAGRCMLEVDRDEDPERGALAAALPLLEALHGRVLHAYAGSGGAGGATANGGTGSGSGAAPPSPSHGGQQQPAVGGQSSGPALEAWDVRRVLRELRERILAGTHVTFSRVFSGGAAAGPQHPLWRLAEACGATVSAACSDSTTHVVSLSGATEKAIWAQQHGRFVVYPSWLECSCFTWRKADESLFLV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VV96</accession>
    <name>A0A835VV96_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_014790</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000106">
        <property type="protein sequence ID" value="KAG2426431.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="10693358at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031499">
        <property type="term" value="C:TRAMP complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071039">
        <property type="term" value="P:nuclear polyadenylation-dependent CUT catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071035">
        <property type="term" value="P:nuclear polyadenylation-dependent rRNA catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071036">
        <property type="term" value="P:nuclear polyadenylation-dependent snoRNA catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071037">
        <property type="term" value="P:nuclear polyadenylation-dependent snRNA catabolic process"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071038">
        <property type="term" value="P:TRAMP-dependent tRNA surveillance pathway"/>
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        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051644">
        <property type="entry name" value="TRAMP_AT-DNA-binding"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543:SF2">
        <property type="entry name" value="AGAP013096-PA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46543">
        <property type="entry name" value="ZINC FINGER CCHC DOMAIN-CONTAINING PROTEIN 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
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        <location>
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        <location>
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        <location>
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        <location>
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        <location>
            <begin position="416"/>
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            <title>Comparative genomics of Chlamydomonas.</title>
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                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
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    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1379"/>
            <end position="1437"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1438"/>
            <end position="1461"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1463"/>
            <end position="1486"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1492"/>
            <end position="1501"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1502"/>
            <end position="1522"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="1527"/>
            <end position="1540"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1555"/>
            <end position="1576"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1590"/>
            <end position="1622"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2433634.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1659" mass="162808" checksum="874DA0C5C3E9398E" modified="2021-09-29" version="1">MLWAPCAYTVGPDTDTLGPHATANHNADSWGQLQPPPAFLRPPPRFAARPAGSSSSGSSSSSSSDTDGSSSSDSDDDGGKREEEGWGRGAGGEGGAGPEPAYGGVLLPPPPRGGSAAAAAATGTSSEAAGGGSYAAVPFSYGDAAAAEEEEAGGDAEERSRERGGGGDAGMPRQPRAQEEHEPEEEEPYSPLFAVPVPDRLSGSLPANQRLHRLLVRTARFVAGAQGGEQVEVLLRVKQAANPNFRFLFPGDRLHAYYRWVVQQQPPPAAGLAGLDAQAAAVQAAAAGAGAAPGAAPGATAGGLVGGRQPPAAAGAPLGPRVPHHLSLPVRNAAPGGGDGADAAEAGAGGGGTGGGGDGGSGSGNLAGGTAAGAQAAASGSAEPKAATALPVGPKPPAAAPQGPTSRTPTPPPPSAHHLPTAPPFALAAPRPAHPAPRPPAQPVSLPAFLYPSTVAYPSTTTATATAAAPTTATAATTATTDPTVDQPPPSQPPPPATRSIIDKLVAYVAKNGITFEAVVRKREAANPAFAAFLAPWGPHHAYYRARLEAAVGAEAVAAAWSGGGGGGGNGGGGGGGNGGGGGGGNGGGNGGGNGGGGNGGGNGGGNGGGGGGNGGGGGGNGGGNGGGNGGGNGGGNGGGNGGASAAAASNGHGASGGGAVAGSASGAAGAAGARAGGATEAAVGGDPGTPPPPGTEEDDHQSAAQPQPQPQQPQQQQLPQPLPAGAASAEAAEAAAAATGEPSSTAPAPAPEVEAVEAGQGEREEENSTAAAAAGQGPVAQQVPSSPRRSGLAAITVSGCARPPPAVTLKANPKLSSSSSSGAQRPPPPKVGGKAAGAAVAGPEGEDALGEEAEAEAGAGAKEPEGALAAPREREHQRRGRGDGLQQPQQQQQQQQQPPQQQQQQQQQQVDGNGDAGEGQQVVMVFEPMPPLDGEEDEEEEEGEGNARRGAGVGGGMRHSQSRSSLGLGGGHGSSGGGSGSASDSDSGSDLDSGSDLDSEPADSDLDEDVEADRRREARRRQRQAQRLRRRGHVARGASAEPPPAADSGEAAAAAAAAAAAAGLDPEAAARLEARRQAARLLLAKAKAQQEVAAAAQRSRAIHHHRHFFLRGAEEEEDAAAAAAAQAGGGGALTAGGAGSAAAAAALERRAGGGGVGGGVSVSAAEVLALERLAARQKEAAAALERAKAAEEEARRRRELEAEAAALRAAELERQRKEAEAAAAAAPKAAAGGSSRFGPPPPTAPPALPAGVAAVAAAAVGARPAESSLAVLRDLVTAAAAAAAQHRAAFEAMLRDPSQVLRTDRRDASGGDAAADSRRGRRRRRRSDGGHSDSQDDSAHTSSGAAAQNASRRDGVKRRRGAAGPRSRSRSRSRSRSRSRDAPKGRRREQQGKEREREKREREKRERDEGGPAGDLDGKGASKEKGERRKEKEQGQKRRRDSKRARSSRSRSRSRSRGRGARGGEKARLKGREREVAREARDGRRGGGSRSRSRSRSGSRSRREGRSGREERAERKRDSRGGHAAPGKRHSRSRSRSRSRSTDRGRGPGGSSRGVGSAAAAGREGTAGPSVGAAPPSAPCATAGSGRPAAGLPLGSAGAPGAASGGAATTGAAGTTAGPAATGALGATAAASGAGAAGAGADLRSRLRQLLAGGGGGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W205</accession>
    <name>A0A835W205_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_012357</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000058">
        <property type="protein sequence ID" value="KAG2434338.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="545881at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050697">
        <property type="entry name" value="Adenylyl/Guanylyl_Cyclase_3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="652"/>
            <end position="677"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="3">
        <location>
            <begin position="2325"/>
            <end position="2364"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="794"/>
            <end position="898"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="934"/>
            <end position="1102"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1164"/>
            <end position="1288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1309"/>
            <end position="1339"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1434"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1470"/>
            <end position="1489"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1494"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1648"/>
            <end position="1674"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1696"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1811"/>
            <end position="1860"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2122"/>
            <end position="2144"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="398"/>
            <end position="407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="408"/>
            <end position="421"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="846"/>
            <end position="858"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="934"/>
            <end position="951"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="978"/>
            <end position="997"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1002"/>
            <end position="1022"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="1039"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1273"/>
            <end position="1284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1446"/>
            <end position="1456"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1497"/>
            <end position="1507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1515"/>
            <end position="1529"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1750"/>
            <end position="1759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1760"/>
            <end position="1776"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1831"/>
            <end position="1840"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2434338.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2425" mass="242819" checksum="79254A733F866AAD" modified="2021-09-29" version="1">MAVTRPPAWSAEANTVTSAEHLVVVCGLHPSQPTLRTLAADHSRRALVPGADERLAVVDVLVEKSKANVTVNARAVGRAEAAVEVLLRAHAAGNTSWLRQLNASAAAGAELPAEVLTPRLGSADGPAAAPLLLLYRRDWWQRLVEIWGLGGNSGDDSGSGGGSGNTTFAEQLLPPTWDLLVRLLGVLRNSDLDGNGSADHVLCADLQPGCKGWAVLAAVYASVAQTQGTQQGMWFNATDLRPAVGGPAMQAALQTYAALAASNAAPFTPGGAAVSLSNVSVSPDDLLQGGGGSGSSGGGPACGAVNPLFAAGRCLFTIDWATAALRLTQNDAQGMNMTGHVGAAPLPGSTLVANRSASSATQLQPCTPLSCPNASASDSAQLAAAEQLLLRLQAAAKDVPPTAAPTQQPAPPPQGPQPQLQPPLLLVNRAPLLGEASPAWAVEPRQAAASYLRTDDFVRLVDFELGLKGAALLAAARARAAGAGSGTGNSSSAIGTMVSSLAGATATAAALVAMSAPEAAQLLDLHPADLAAVAQAVGASLDHPNAAVDISLPYSAEYRAVLDDLAASMLQLVANTTAVGNGSAAPEDQVAVLTASASVRVVAVGTAFPYPAILLRLYWQATGFTPPSQAGDGGTNSSEGNVASTQSAALRIGLPVAVAVGGALALALLGVVCYAFVARRRASERALFRAMKPPGAGPTTTLVMTDVQNSTLLWEVLDVHVMDECLSLHHHVMREAIAANRGYEVFTEGDAFCVVFYSPDSALGFALHVQEHLLTQPWPEELLQQPDGCEVWARRCAPQPPPQSSLTREQAGAGAGMVGPGALPVLLEGAVEGPSTDGTNTPTRGLTGGGANSDGGSWGANQPSRLRPARGPSPLRQATSASGLRSGRDPEPAPAVSAAPKPAALLAVLLDTSGPLQGSPTEGAAAAASLLPAEAAAGPTAQQDPQPAPQQGGQGGGAGVDDGAHEAVVALRPGALLVEEDEDDSDKDGEAGGEEEVERPSNRSSRPSAPSRALRPVPRPSATGLLAPAPPEGELILPVRPPPPLEDGPFPAPPPHPRPSGSGTAGGARPPRSSRRMLPAAACLSDNGFSPQPPPAQPQPAALAAAPALLVAPMKPELPELRQERSLPLAQGQDAAALADAAAEVAGDEAAAAATAAATVLVTSRRPSQNGKAGGAQAAPITAPAGRGTGGGSLANGGLVTASQLPRALPPPMSATGGRPVSGSNLPRPNVLPGGGPQALPRQQQQQQHVSGKLALMAGGSSQAGSGKLPIGEAEDEDDDEDDATRDWRKHINWNAEDATPPPLVSSLGSAFGPGYEQLAAPDGASATLPEPTAAHSPRAQAQQQHAAAAWQVAALMGGERHADGNGSGATLRATFDGSTGSWAPVSAHAAAPGDAGALALGVGAAHTKPLGTATLGRFRASLPRLFQTNASLPARPQLDLSNGGASVGGAGTGGGEAGTALRQAANVYGSSSGGGARAPSGPLKTRPLPMLHLATSMPAPGSALPMPGAPPPSRAASRTPASALAAVGAGHSSGASHALSSTAGRRGTVHRLSMALYRTNAASNAYSNVYSNAYSNCAATSNAAPFISPSATGRYGLNPSASMAAYGHGYGPDMYGAGAAAGTSPFMYGYGSSNHHLPLMGPAYATSPPASVTSEAPMGTPRLASGAGPRRGSLPRFVASLANSLRRSKATLLGGGGAGSSLAGAVPSESSLACPSTSPPSGVPLGPHPLHGNSGQPRRSHGDDPSARQDPSNHQLSRASSAAGPAPAHTSPSTATAGAAAAAAVSSSGQLPSSGLLMVAVAPLYVGPDDPAADADAPTSPAEVELGGMQQQQQQQQQQPTAAGGGGLRPGRASLMGGGSVTSPLDALWRDLNSVNSLCRQTDIGDGSGAGGGSGVAAWLASAGCTIGGVLCSMFTTVPPDQVTPRLRTRLTQEAGAAPAAGEPRLSSSALLAKLGGRSVVGGGGATAAAASAGSALMAAVNGLPSPGGDRDRGSGGTFSGYAGFGLGAAGGGGVGGAGAAGGEPVPVLAFRGLRVRVGLHSGVRVNEVVSLGKEAAGAAADYKGDVVQICKEVSDVAMGGMVVLSGSAFRALQLLAGGRGKSRAPEAMLLHLGEHVIKPPQAAEDRPSRSAGTGGQPDAPPPTRELYAAVFPSLACRLALLPSPVRTHSELVPGCLSAPAGLVAPVFCNVVGVEALLAWEALVQERLMRAAAVASAANLAACRPLVGGEAVAPLDTAVGGLGMVREALDLFGDMAQEAASRHGGYVVASSADGGHWVLVFGCAEAAVGWGLDMLQAMLTAEWPDGFLEHELTEEAWEGGVLVERGLRLRIGVDFGRAMVRLVPRSGRLDYVGRPMNRAARIAAKAKAASVLMSGAAWSAARPALGSSVAATNLGTMQLKGVKEQLELWEVRAVRTGDAEHYME</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W2Q9</accession>
    <name>A0A835W2Q9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Methyltransferase small domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012093</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000055">
        <property type="protein sequence ID" value="KAG2434894.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W2Q9"/>
    <dbReference type="OrthoDB" id="269872at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003676">
        <property type="term" value="F:nucleic acid binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002052">
        <property type="entry name" value="DNA_methylase_N6_adenine_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052663">
        <property type="entry name" value="RF_glutamine_MTase_cyano"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47441">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47441:SF3">
        <property type="entry name" value="RELEASE FACTOR GLUTAMINE METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00092">
        <property type="entry name" value="N6_MTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="123"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="193"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="93"/>
            <end position="103"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="104"/>
            <end position="116"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="194"/>
            <end position="222"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2434894.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="542" mass="55277" checksum="9A0009649389A8E0" modified="2021-09-29" version="1">MRGVLGTPPAAECPAAMTRGVHALGRLLPRACPLAGCSCCSLPPASSPSSSLPSTGPLHAPPVPRRAAAAVRSSTSAAAASSSPSSPTPAPASKPVAAAAGPAAPSPAPSPAPSPAAPLASTPQLPLCRRPAAHVEPLAAVERWRRAQAERIAALGDSWEQRDGGPGAELLLRELDWVLDDVIEAVSYGPPPAAAAAASSSSSSATASTTTSASTTASAPAATAARWEETSWRLLEPALRAAATRRRDTSGWAVRLREPTSVLWEWWERRLTDRVPFQYLISSAHWHTYVLAVGPGVLVPRPETEIFPRLVAEALARRPGLAAAPWADLGTGSGAIAIAAADVLRKKNKAAEVWAVDLSPTAVAYASFNAALVLGTAESSSSSSSSGNGATQPAAAPQHVRVALGSWFGPLRAVGLAGRLGGVLSNPPYIPRREMSGLQEEVGRHEPAGALDGGEGPGLDSLQELCDGAAEMLAPGGLIAFETAGGEQADLVADLLRRQEGAAVAAAGGPDGGGSGAFEDVEVLEDCCGVRRFVRAYRRAAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W314</accession>
    <name>A0A835W314_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">PAS domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_011919</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000053">
        <property type="protein sequence ID" value="KAG2435418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="533766at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009881">
        <property type="term" value="F:photoreceptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014954">
        <property type="entry name" value="DUF1825"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000014">
        <property type="entry name" value="PAS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052994">
        <property type="entry name" value="Tiny_macrocysts_regulators"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057352">
        <property type="entry name" value="TPR_TmcB/C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31600:SF2">
        <property type="entry name" value="GAMETE ENRICHED GENE 10 PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31600">
        <property type="entry name" value="TINY MACROCYSTS PROTEIN B-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08855">
        <property type="entry name" value="DUF1825"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25474">
        <property type="entry name" value="TPR_TmcB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50112">
        <property type="entry name" value="PAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0157">Chromophore</keyword>
    <keyword evidence="4" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0600">Photoreceptor protein</keyword>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0716">Sensory transduction</keyword>
    <keyword evidence="4" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="282"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="375"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="440"/>
            <end position="457"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="477"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="506"/>
            <end position="529"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="1885"/>
            <end position="1909"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2088"/>
            <end position="2108"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2120"/>
            <end position="2136"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2343"/>
            <end position="2362"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="4">
        <location>
            <begin position="2558"/>
            <end position="2584"/>
        </location>
    </feature>
    <feature type="domain" description="PAS" evidence="5">
        <location>
            <begin position="787"/>
            <end position="849"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1660"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1834"/>
            <end position="1854"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2142"/>
            <end position="2233"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2315"/>
            <end position="2336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="2616"/>
            <end position="2655"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="1721"/>
            <end position="1731"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="1732"/>
            <end position="1744"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="1841"/>
            <end position="1854"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="2144"/>
            <end position="2157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="2203"/>
            <end position="2215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="3">
        <location>
            <begin position="2315"/>
            <end position="2333"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="2628"/>
            <end position="2638"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="2639"/>
            <end position="2653"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022543"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50112"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2435418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2686" mass="286530" checksum="0A9631742AE2894A" modified="2021-09-29" version="1">MNEFNNIVKEATQLSGMAGRFPDFDLQGKQMYLDKMQEMSDRYEVFIKRLELSQDPAAKEYLRTTNAQMLEGGFTLNQMFAGLKQSVTEYRKWVEQEERVSGDPVAHQEFLKYFREMWGASVLGRLDLSYLVKTTDPQVILKAQNDPQFWVMLKEISTSPSPAAMTKWMDHPTLGPLVAELWKSAQKGRHANQQQDGQGSDLLDRRSTLENGVFGVLFTLSKENSETRIRIRWVLLKILLDGWQLFATVIQPAKQGWDINPDGAAWSVVSVLNFTWLADLSYSAYLALLYSAVALLVVNIGLCVWVAWCFKEQKFPVVWPIKVLRVFSSIFFQAFDVASLNLLQLGFSCRFTGPVTPHMHMDLFPAYSCASSPHVVHAVTSGIFLLLFVVIALLLNMAEVEVNPLSRRPLALGHSGAEVMAFAIKALLTLVDVFLGWRKVAACAYLALSLALAWQYLRWNPNLVAWVNYLKAGVSGSIVWCCATLMLLVFAPGVKSSEQSSWSSAMTITMLAGLAPAFGVGAAMSWFAIRKMTHTALQAMADAKPDQPLQDICDNLDDPRDVEIVARSARVWRDRYTLDPDAVQKAHNIIKAGLAMFPGSAYMVLLHADFMIDVLGVSQSGARRIEDARKLSPSLMCRFMMFVRQQQATQKAAGSHANDGVSMDLLGYVEYQRKQRMVVRLHREALQAMCNFWKALDASRVSFTHLSKALGKIESSVSQAQAAYRVVLESYGTNPKLIRLYGKFLEKIKNDPWGAAEYFAEADRLEEVKNGDARGPLLPDGTPLGRMDEMAAAVLVINATGEIQMANKQTHNLFGHKRGTLEAKPLAMLLAPHCARRVSEELARMVANSSVTALMNGGRTESGRSTDGSVMSDGPDLVVVGMHVDRVAFSVKLSIRKASGVGEDSTFIALLEPAPPVPNMAKVWVSPNGIVAAADPQFVAHFGWKATEVNGSNLTALMMVQSTESVVMCGGQGEDEEVAIPKTTTESATETVKRLLRLAKVNSDTVGNKPVQGLHCLVAHKYDSQPVPCNVTVVETTSAEISVHELRLQLASDDPAQLLVVNRKGSILHASTELASALKDSAAAGTAGGGPRFGGVTGQISSRIAGAGGLSGGGGGFVFGADLLTGFTLCDFLPAPWKDMHVRFLKDITSSSPPTRSLWSCRKAAAQPTLELRSMTGRPLYMHVSITTGDLNGESTHVISLQRSSLEAALSERRVRLTVSEDGLVSAASRGLALQMLGLEPGRVIGRGLWEVVSEEPADTPGKAAVRASTPAGPHLLGALIERALANPGASWRVDVSNPLPRKSGGGPALALARQQSAMVRAKAAVMQVHVEPPSDEEAAAGQGNRVYVDLWPLHAVSGVLQLDAAGRITSVLEEHTRPAGLLFGLHHDALVGEALSSLVTMPPGRTTAAELLSLHGAKKSNLKTKQKDVAVKVGPVHKLRATHTDGKPLVLDVQVVGKPGPNEPLIAILRLHAAPMLPAAAAVAPAAAPPPARAVDGVANKGGTAAAETAAAAGVAVVAALNRKPSLDDLLEKVEAAEVAAAAGKVAAGARNSKESFSVGQVHTPPTGGSLRRGDSTVVKAIGTDAAAAVAAAAAAAVAAASGSMEDAGAAPLPLPMPANLLAGMSNSSLPVPGVTAAAAAATGRNKLADLVRSVGGEQQAAGSGKMVLGSGDGSLPPAPRTRPGASRRSNNGDGGSVVAAELPHAVLPETTGVDVQSVDGDDREEDQDSEGGGGGGGQGGKGKGADRILSWVASKGAYYQNSVAAKTDDEGSVKALSEDACSDIHAGNSDMTGAAYAASERTERTAATVTTMATAQTLAGLKSATAAPDVPYADDDAASEGGQSAMSAQSASGAEYKRGKRFRKLVKLMDSGQAQQVQKRFKLHALITVGILAAVHVVCFVLTVVSIGQQRASMLQLGRSAELQLSLHQILADVRSLDVIVQNKSLPTLYTASDSSMFLSRISVNAEKIKDRLNEILQNHHDSDSPVMALFYFTTIRVWNGRDQNGSDVFTNTTIWDFGTRIYSMTKLVEQSGAQWLADGRSFVDQDPGQFLIKSGPDFFRASRRILDALLYTAVDSAKKVNTLQLVFLAVEGAAISCAAACYLAYLLRAVAAQRYKLYGTFLVIPVGLTRALASQNTTLLVDEDEDEDEDDEEGDRTAMAQANNDGSDGENEDGAGKQAAKQKRTLGFSASAVTPSADTPGGGGSKGAGGAGPRKKVAPWDAAQREGTRVPAGAVRASDVLLGGDDDDGASGLIAQQRTYTGSFNSSRSRGGFGGCWGWARRLVFRSRSLGTVAPLPTTRLGSILGPRGWAPSTQQAVAQQPPGASSSSKRTLKYDSNDTSVMLTPFVMWSVLVIAFYATAVVEMRDIVDTVAVHSVVNFMNARTSRNVFLSQELAVVEDPAQVPAKQLALQAGVKLVRDAFYTLQLGNRAYLTAGNATERYPLVTTGLSHASARLEDLFYGSGSCHRLFPEYLPCPGPEYRYYEISHTGFDTMMQQFLISLEAMAFNATGLPQGLGNKNFDYIYNVGYKDMIGAILQIKQEHYNIIVALFDRIMLLHIILFLLLWVIFAGFLFILLNPLIKRVSKERRRIAELMSQLPLELDVEKLVGRALGTGQQPPQGPGGVVSSGHSHTAAAGGGVAGAAPPGGGADATSKWKAIIKQASTNFKAGGKRASTDQLGNLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WB09</accession>
    <name>A0A835WB09_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_009228</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000030">
        <property type="protein sequence ID" value="KAG2444030.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WB09"/>
    <dbReference type="OrthoDB" id="8123449at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12283">
        <property type="entry name" value="RRM1_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd12285">
        <property type="entry name" value="RRM3_RBM39_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029123">
        <property type="entry name" value="RBM39_linker"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006509">
        <property type="entry name" value="RBM39_SF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01622">
        <property type="entry name" value="SF-CC1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48036">
        <property type="entry name" value="SPLICING FACTOR (PAD-1), PUTATIVE (AFU_ORTHOLOGUE AFUA_1G15810)-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF15519">
        <property type="entry name" value="RBM39linker"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="3 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="153"/>
            <end position="230"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="267"/>
            <end position="344"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="552"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="1"/>
            <end position="11"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="31"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="74"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2444030.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="647" mass="69488" checksum="4AAD796BCD1C0B4F" modified="2021-09-29" version="1">MDDWDYLEKQVDAPGASPKAAAQNGSPSQPKEGRESRERSEKPKEKDRDREKERDREKDRDKERRRSRSRSRDRKKEKDDRRRSRSRDRREKERRSRSRERRDRDRDRRDDRDRGRRAEPSYERRRERDRTPPEVRAAREAEKELREMERSTRTAFAYNLPLKADERDIYQYFSKVGKVVDIKLITDKATRRSKGFAYIEFSKVEEVIAAVALTGSVFMGQAIMVKSSEHEKNLAWEAQQQAKQSQLKAATLLSQAGGDNPVPVGPCKLYVANLNQAIAEPDLQQLFAPFGNIESVQIVRDTNGKSSGYGYVTFTMVLDATKAQEHWNGRMVVDSALKVSVSSLAPSATAAAAAALPVLAATPNLFAAGGLGAALPGALPGALPGALPGALPNLSALGGLGGTLNIPSDVASRFGLAMPGAAPAAGAAALPGALPGLVLPGPPAVAPAAAVPPPVVDSGIGELDEEESRGGLKLTSDKRQALMARLATSAGLAPHTPALPPGVAVPGMPAPVALPGPPPLPTAAAAAAGPKLDPGLSLIQSVLGPSSPIPTPCLLIKNMFEPAEAEAESGPGWAEEIAADVQDECAKYGAVLHVHVDKASKGCVYLKFGSVEAASAAQHAMNGRWFAGRQIGVEYQFLQPYNSHFKC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WB18</accession>
    <name>A0A835WB18_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">SNF2 super family</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_009019</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000029">
        <property type="protein sequence ID" value="KAG2444076.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="2801544at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043596">
        <property type="term" value="C:nuclear replication fork"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004520">
        <property type="term" value="F:DNA endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004386">
        <property type="term" value="F:helicase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031297">
        <property type="term" value="P:replication fork processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd00146">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="CDD" id="cd18793">
        <property type="entry name" value="SF2_C_SNF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10810">
        <property type="entry name" value="Tandem AAA-ATPase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014001">
        <property type="entry name" value="Helicase_ATP-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001650">
        <property type="entry name" value="Helicase_C-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035234">
        <property type="entry name" value="IgGFc-bd_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022409">
        <property type="entry name" value="PKD/Chitinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000601">
        <property type="entry name" value="PKD_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035986">
        <property type="entry name" value="PKD_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038718">
        <property type="entry name" value="SNF2-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR049730">
        <property type="entry name" value="SNF2/RAD54-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000330">
        <property type="entry name" value="SNF2_N"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766:SF3">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45766">
        <property type="entry name" value="DNA ANNEALING HELICASE AND ENDONUCLEASE ZRANB3 FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00271">
        <property type="entry name" value="Helicase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17517">
        <property type="entry name" value="IgGFc_binding"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00801">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00176">
        <property type="entry name" value="SNF2-rel_dom"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00487">
        <property type="entry name" value="DEXDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00490">
        <property type="entry name" value="HELICc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00089">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49299">
        <property type="entry name" value="PKD domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51192">
        <property type="entry name" value="HELICASE_ATP_BIND_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51194">
        <property type="entry name" value="HELICASE_CTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50093">
        <property type="entry name" value="PKD"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0347">Helicase</keyword>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Helicase ATP-binding" evidence="7">
        <location>
            <begin position="639"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="domain" description="Helicase C-terminal" evidence="8">
        <location>
            <begin position="936"/>
            <end position="1083"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="6">
        <location>
            <begin position="1678"/>
            <end position="1742"/>
        </location>
    </feature>
    <feature type="domain" description="PKD" evidence="6">
        <location>
            <begin position="1755"/>
            <end position="1838"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="20"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1097"/>
            <end position="1127"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1158"/>
            <end position="1255"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1975"/>
            <end position="1995"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="24"/>
            <end position="34"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="111"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="150"/>
            <end position="195"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="219"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="229"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="262"/>
            <end position="286"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="302"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="327"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="5">
        <location>
            <begin position="340"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="365"/>
            <end position="374"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="406"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="484"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1098"/>
            <end position="1111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1112"/>
            <end position="1126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1175"/>
            <end position="1196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="1197"/>
            <end position="1206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1207"/>
            <end position="1219"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1241"/>
            <end position="1250"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="5">
        <location>
            <begin position="1986"/>
            <end position="1995"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022806"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50093"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS51192"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS51194"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2444076.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="11">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1995" mass="207393" checksum="2E0D8B94FEF3D480" modified="2021-09-29" version="1">MDDDDDLFCDIDVDSLVARHQGVPAAAPQQPQPANVQSLRPPPPPHQRHQPQQLCAQPAGPKPLQAHNSNLALPHQPPPGATWQGKAAQHQGAHAAPPPPHRPREPHRPHGQQQQQQQQHPAPGQAALPHQHRPPVPLHQQQPSYPNHPGPSQHHQAQHQQPHVQEQQRPPQHLLPPQGLHAPPQPQGPQQQGPPHAHPNHAHQYPPHPPHPHQQLAGPGPGAAGPGQAGPQSHPPSHGGPHGPPVPQQHLYPAPHPHPHPLQHQYQQAQQHPPQQHPLSHQNQPPHQQPPHQQPPQWSTGPMPPQYQPVPQHGPLPSCPQGGPGYLPQHLQHPQHPLSGQPPPAPGGPPPQPQHQPQPQPQPQPGAAAAGAPGIASNNPFAQYAHPQHHLLHAGLNGPGQGAGPNGPAHAGPLPQGSAAPPAHAHPHPLAAQRQQQAQAQAQAQGHPLQQQQQQQQQQQGPPFQQPGAGPPHQQHPQHPPHPQQQHLPGAAGPDAGVGPGPGPGQAPAARQARVSYTGFIRLEDRGRFAFKVGFHKGLEEVWRTMKGEWDKADGQWVFPIAMYRHFKDSLTDGRLRHRGVDVTVNQDVSPPPFVLRMLDEAAGRMSEEKLYDRLLRFPEEGPNSLDARMMPFQREGVRHGLRHGGRVLIGDEMGLGKTVQACCLIKAYYGEDVPVLVVTPKSLREAWADALYMWLKLTDKEVCVIGGKEDVALVEGYKLERSTVRVFVVSYDTLSKYVEPFEALRPRMVVLDEAHYIKSMSAVRTKAVLPIVQSAKRAVLLTGTPAANKPMEIMSLLVALVPKAKITQKDFGHRYARQDRFNKYIGSRNEQELNRLLLGTGVMIRRLKSEVLKHLPPKRRQQIFIRLPDKQARAVSEASKKLEGLKQVVAAMMDGGGGGGGGGGALAGAQREAQAQIMALWRDNARLKGAAVAEYCTDLLEGEDPPKFLVFAHHKDLLNTIEDQVRKTRFKYIRIDGDTPGEDRNKLTQRFQDEEDVKVALLSIKAAGVGLTFTRSSLVVFGELSWIPGDIQQAEDRCHRIGQAATSVNIHYLLVRGSVDEIMWDCLQSKLGSVGKALDGSGAYIKVDATRELCGLGQQGAGPSGGGAGGHQQQQQQQQQQQQQQMDGFLTTAAGGLNHHHDGDEEDDFIQQPFAAARAASGGAAGPGPAPAAGGNGGAAGGAGAAGGGRGGGMVRSGSSSSSGRASGGPAGTPGGAGKTRPIESFFTKPPSPAPAMLPGGAGAGGATGAAGPRRGAGAVAAADIMAVPAVPAAAAAAAPQGLAGAGQKRPRVVDTIGADFIFSFGPNHPSVAANAVSQIAVSGTCSGAGCGISVSFPNCPAGACPASPVALDLVGSTANGDTILSKLITLTGPYAPVSGPNPGLYGGKAVRMTATGGDVSVEAVTGAIQSGDSTAIFPMDALATSYVVGGYKAKQLPPTSAWGKRFLTPTVPQRPATLYKLVPAEDGTTISLDGGAAPAGCAAASYGPSSTCSFSLPGGSFHVLDTSKPALLLMFSPGQSLGGGSGDPFATQIPHVDAMLSSYTLMAPGTLAGTSGLTNFLTVAFEGADTERAGLEVKGGAGIPWTWSQVTVAGKTFQFGVGQAAPGTYSLSHTTPGKTFSVQVDTVASYVAYGHTPGFALVGPVDPPVIPVPLTVTPSCSIDLTGSVTVSATAMDANGDLVSIAFNWGEGSAVNEVVTFAATGSYTAAVTHTYTSPGSYSITAFATDAKGATSATVSTTCQTVVVSNSAPAIPSPVTLSTCAVDLTGSVTASAAATDSNANLVSISFSWGDGTADSVLSFTATGSYPAAASHTYASPGTYTVTAVATDALGATSTPALGSCAITVTGPTTAFVTGGGWILSPAGALRAKPLAVGKASLSVSAKYQPGSAKPSGQGSNFNFKATELTKLTVVGSSKATVWGKGMVNGGAGAYSFLVSIIDEAVSGDGKSGNPPDYYRMRILDSANAVVYDNGSGSDGADPVTPLGGGNLEIHK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WCP7</accession>
    <name>A0A835WCP7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008847</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000028">
        <property type="protein sequence ID" value="KAG2444977.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WCP7"/>
    <dbReference type="OrthoDB" id="546603at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="21"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="87"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="323"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="96"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="111"/>
            <end position="122"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="124"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="194"/>
            <end position="203"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2444977.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="415" mass="43002" checksum="AD5E3C1D1BFCF7CA" modified="2021-09-29" version="1">MARAKESREVARRVDQIVKAGVSEFEDDSKPAGPLPVAQMPALPPPPMTPPTGASKPAYQAGAPLSYNAEEEAADTSYFPEQVSLNIGGGGGGFGRPAAAPAAMFGAPPAQSSSLRSFQPMDSQAPLAQAPAPQPAMLPALGAQTQMRQQQQQQTYHQQQLYQQQQHYQQPQTLPSLQHQQPELAYEPQEAAAAPPPPPPPAPTDDIWSSLQSAYRIKDPPAGPASAHSKGSSGRGAGKGAPSGEVLVLGDDDPFSGGKGMVAPNLNGTMNRTSGFGGRGGQAGNTAQPSRPAAAAKSGGWGAGNMARAGELMIGAADDDWLEGGDARQQLPPAGGFGGRGAVSQRSDEYGGGYNQQPAAGLNKAPLAQGRHADDILCEDVEDVDMLLEDEMQGIADKNLANKLAAFDAQFNDDD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WCQ8</accession>
    <name>A0A835WCQ8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Maf-like protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_008884</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000028">
        <property type="protein sequence ID" value="KAG2445015.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WCQ8"/>
    <dbReference type="OrthoDB" id="10267058at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0047429">
        <property type="term" value="F:nucleoside triphosphate diphosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00555">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.950.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00528">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029001">
        <property type="entry name" value="ITPase-like_fam"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003697">
        <property type="entry name" value="Maf-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213">
        <property type="entry name" value="BIFUNCTIONAL DTTP/UTP PYROPHOSPHATASE/METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43213:SF5">
        <property type="entry name" value="BIFUNCTIONAL DTTP_UTP PYROPHOSPHATASE_METHYLTRANSFERASE PROTEIN-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02545">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF006305">
        <property type="entry name" value="Maf"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52972">
        <property type="entry name" value="ITPase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2445015.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="209" mass="22230" checksum="D3EABD01DF4A4A92" modified="2021-09-29" version="1">MASSIKRPLPASLCHDLCRDGRSKPKGAVLVSSFDEKLPKDRFPGGGEYALETARHKALDVAGLVSEPVDLIISADTVVESNGVILEKPDDDEHAFAMISSLSGREHQVHTGVVLVLPQEADPATGSPPLIRSFVTTTHVTFDSLPEEAIRAYIATGEPFGKAGSYGIQGAAGAFVSGLRGCYFNVVGFPLHRFCSEISALIKEGKLKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WDS6</accession>
    <name>A0A835WDS6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Bidirectional sugar transporter SWEET</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_008801</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="12">Mediates both low-affinity uptake and efflux of sugar across the membrane.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3 12">Belongs to the SWEET sugar transporter family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000027">
        <property type="protein sequence ID" value="KAG2445335.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WDS6"/>
    <dbReference type="OrthoDB" id="409725at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051119">
        <property type="term" value="F:sugar transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.1280.290:FF:000004">
        <property type="entry name" value="Sugar transporter SWEET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.290">
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR047664">
        <property type="entry name" value="SWEET"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004316">
        <property type="entry name" value="SWEET_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791">
        <property type="entry name" value="RAG1-ACTIVATING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10791:SF224">
        <property type="entry name" value="SUGAR TRANSPORTER SWEET"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03083">
        <property type="entry name" value="MtN3_slv"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="10" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="11 12" id="KW-0472">Membrane</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="8" id="KW-0677">Repeat</keyword>
    <keyword evidence="6 12" id="KW-0762">Sugar transport</keyword>
    <keyword evidence="7 12" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="9 12" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4 12" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="7"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="47"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="133"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="165"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="12">
        <location>
            <begin position="191"/>
            <end position="212"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004653"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00007809"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022597"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="RuleBase" id="RU910715"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2445335.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="248" mass="26446" checksum="D81E56ABF7E711AB" modified="2021-09-29" version="1">MGSSGNVLLDTVVPGMGAVISILMYLSPLKAVLKAQREKHLGDLNPIPFSIAIANCIAWLGYGLLKKDPFVCAPNAPGVLIGTFMSITAHGMADEAAKQRIRFVVCLAAGIFPFLGVYTAFFADSAAVQQGLWGLAGNIICLVYYAAPLSTMWDVIRTRNSSSILVPLTMMNTLNAALWTTYGVAVGDPYIWAPNGIGLALSVMQIALRLVFPARAATPLPSHTHHSIEGGIDVAVIDRRAPRLRSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WFV3</accession>
    <name>A0A835WFV3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Nuclear pore complex protein NUP96 C-terminal domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_008242</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446672.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WFV3"/>
    <dbReference type="OrthoDB" id="3797628at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR021967">
        <property type="entry name" value="Nup98_C"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12110">
        <property type="entry name" value="Nup96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Nuclear pore complex protein NUP96 C-terminal" evidence="2">
        <location>
            <begin position="584"/>
            <end position="945"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="131"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="875"/>
            <end position="900"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="116"/>
            <end position="127"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="429"/>
            <end position="441"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12110"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2446672.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1170" mass="114702" checksum="51FB89C8C44D265A" modified="2021-09-29" version="1">MSEARAQLRFGDDPTAEAEVSGGVVGPPAAGGSIITGSVALGGGAATAAAAAAAADAAMAEPAPAAVPLQHALPASLAHDPVRVRALHDAFFGGGGGGGAPAAVAGDGWTQLPPQPHHHHHHHHHRQALQAAGSMIRGALPMGGAGEAARGSAATAAAAAAAAAALREGGGATSAAPSGPMATTWRRPAAALSAGAPAAVMARGAALLSEVGGGDSGGGAGAAGSGSPISLALARAVTVRPPPSAPDGPAGAVLPLKEVATARYLTDAGLAMGRSFRVGWGPGGKLVVPGAAEATTATEICVTRVRVEGEGAAYGEVSGGGAADGEEAEGLEALRERLRAALEVHLAASKPRESAAAAAAAAAAAAATDANGDVAVTDAAEGAAAGGAPPPPSVPPHWRLCVDNRELAVLVERYVRVCDQQLHNLLGGGSGGAAADGGASGAGASSAVDADHPDAARLRHEIDTWRLLEVLFARIDGEVPEEAAAAAAGGAGGAADPMSLTTPPATPGNSLALVSSGDHDMVGGGGGGGDGAAAAAAGAAPPRTLLAALQRRAALGLWLQRQARRRVEEDLAALPHGSTPAAVALHLLAAHQLAAAAGAAVAAGDTRLALLISRAGGRSSAKQQLAAQLALWQQQGFSEHIAPERLAAYHLLAGQVLETQRLLSLDWRRLLGLQLWYAAAPTSSPLTALQRYLMDRHTEPGVVPHPAPYHVEGLQPSATGAGSNSGGSGGATDVQWELLQLWSTTPAAATADCLADGRLATATGVAAAAERARQGWLAGGGCSRLLRCAGYSPNPLDHSLAWHLMTSLQACEVLPKPGAASDAAAHAGSPPPAYESELLGTTLEFISQLLLAGGLCEWALYVALTIPDLPAEAGAGGSGAASAADEEGEEGAGGGAGGSPAVRTRVVRELLAMTAPEWMGDSARESFLTNTLRIPAPLLAEARATWAHYARDDAGRCAALLAAGSVAAAHEVFTSAVAPGLFLAGAWEQLAALVAALEPAAAALPAWSAGGGLYGNFLALFGRQLTAAAAGAAAAAAPPGVGMQELLGFAAQVQEGQLALDPRVGGGAGAAGAGGAGGAAAAPVVGADEAAERSRLRRRLVLGRMAARVHGALMSCSVAGPGGAAAGWEERSVGLQAGLALQGCLAAELQLGGVAVAVAEAGARVAACSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WFV6</accession>
    <name>A0A835WFV6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">PDZ domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_008209</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the peptidase S1C family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446636.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WFV6"/>
    <dbReference type="OrthoDB" id="4217619at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004252">
        <property type="term" value="F:serine-type endopeptidase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006508">
        <property type="term" value="P:proteolysis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd00990">
        <property type="entry name" value="cpPDZ_AtDEGP1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.40.10.10:FF:000001">
        <property type="entry name" value="Periplasmic serine protease DegS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.42.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.120">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.10.10">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051201">
        <property type="entry name" value="Chloro_Bact_Ser_Proteases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039382">
        <property type="entry name" value="DEGP1/8_PDZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001478">
        <property type="entry name" value="PDZ"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036034">
        <property type="entry name" value="PDZ_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009003">
        <property type="entry name" value="Peptidase_S1_PA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043504">
        <property type="entry name" value="Peptidase_S1_PA_chymotrypsin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001940">
        <property type="entry name" value="Peptidase_S1C"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343:SF2">
        <property type="entry name" value="PDZ DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43343">
        <property type="entry name" value="PEPTIDASE S12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13180">
        <property type="entry name" value="PDZ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13365">
        <property type="entry name" value="Trypsin_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00834">
        <property type="entry name" value="PROTEASES2C"/>
    </dbReference>
    <dbReference type="SMART" id="SM00228">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50156">
        <property type="entry name" value="PDZ domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50494">
        <property type="entry name" value="Trypsin-like serine proteases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50106">
        <property type="entry name" value="PDZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="2" id="KW-0645">Protease</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0720">Serine protease</keyword>
    <feature type="domain" description="PDZ" evidence="6">
        <location>
            <begin position="226"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="69"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="81"/>
            <end position="100"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010541"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022825"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50106"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2446636.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="356" mass="36307" checksum="0DCB7403B7A66157" modified="2021-09-29" version="1">MNMLELPQGQGSGFIWDSTGHVVTNYHVIQDASDIKVTLSGGEEFSAKVVGVDQDKDIAVLQIGPLGPAASEAQGDGSSKPPQQLLAAAPPGVSGPAPAAAAASALPGSLPAGAVPVPSVPVEPVRVHPLSLCSSSADIVVGQKVFAIGNPFGLDHTLTTGVVSGTGREIQSISGRPIQDVIQTDAAINPGNSGGPLLDSGGCLIGINTAIYSPTGANNGVGFAIPVDIVKSSVGQIIQYGKVTRPILGISFAPDQSSEALGIKGILVLSAREGGPAWRAGLKGSSRDEYGRLVLGDIITAVNGVKIKTSSDLYRVLDKSQVGDTLRIQVLRENSTFEVSVVLDSNNPPPPEQPKA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WG86</accession>
    <name>A0A835WG86_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Peptidase S59 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_008242</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
            <location evidence="1">Nuclear pore complex</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nucleoporin GLFG family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WG86"/>
    <dbReference type="OrthoDB" id="3797628at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0044614">
        <property type="term" value="C:nuclear pore cytoplasmic filaments"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008139">
        <property type="term" value="F:nuclear localization sequence binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017056">
        <property type="term" value="F:structural constituent of nuclear pore"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051028">
        <property type="term" value="P:mRNA transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000973">
        <property type="term" value="P:post-transcriptional tethering of RNA polymerase II gene DNA at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006405">
        <property type="term" value="P:RNA export from nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034398">
        <property type="term" value="P:telomere tethering at nuclear periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.10.2360">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1610.10">
        <property type="entry name" value="Peptidase S59, nucleoporin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037665">
        <property type="entry name" value="Nucleoporin_S59-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007230">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036903">
        <property type="entry name" value="Nup98_auto-Pept-S59_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198:SF6">
        <property type="entry name" value="NUCLEAR PORE COMPLEX PROTEIN NUP98-NUP96"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23198">
        <property type="entry name" value="NUCLEOPORIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04096">
        <property type="entry name" value="Nucleoporin2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF82215">
        <property type="entry name" value="C-terminal autoproteolytic domain of nucleoporin nup98"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51434">
        <property type="entry name" value="NUP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0509">mRNA transport</keyword>
    <keyword evidence="7" id="KW-0906">Nuclear pore complex</keyword>
    <keyword evidence="8" id="KW-0539">Nucleus</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0811">Translocation</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="Peptidase S59" evidence="10">
        <location>
            <begin position="877"/>
            <end position="1019"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="16"/>
            <end position="38"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="775"/>
            <end position="836"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1035"/>
            <end position="1070"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1134"/>
            <end position="1167"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="9">
        <location>
            <begin position="807"/>
            <end position="825"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="1036"/>
            <end position="1046"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004567"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022816"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023010"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023132"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS51434"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2446674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1167" mass="109286" checksum="6E1EE23745178F0B" modified="2021-09-29" version="1">MFGGAFGGTTGFGQPAAQPAFGAQPAQPAASPFGGAFGAPAQQAASPFGAAAPAAGAPLFGAQSPAPAFGAAAPAAAPAFGAQTATGGFGAAGFGAAAKPAGFGGFGATAAPANPFGATTQTPGAFGATAQSAPAFGAGLGTAPSFGTTLTSAPGGFGATSTPAFGAPQSAAAFGGFGASSAPAFGAPAAAPANPFGAPAAGGFGASATPAFGAAPAATGFGAPAATPAAPFGSTTGNLFGAPAAAPSPFGAPAAAPAAGGFGGFGAAAPGAATTGTRNVPYSKTKDPDAAAGQVTFLMSISALSNYNPPNAAKSHEELRWEDYEAGVKNQSAGPAPAAAGAFGAPAAGATGGFGGFGATTTQPAAGGFGAPAANPFGAPAASAPAFGASTTPAFGAASTPSLFGAAPAAATPANPFAAPTTTPAFGGFGAAPASQPSLFGASTATTGAFGATTGAFGATTPFGGAASQPAAAPFSFNSSSPSTFGAASAPASGGLFGAPASAASPSPFGATGTFGAVGSPFGAASSASALGTSTFGAFGATAAKPASPFGAPATTTPFGATAPATGGGLFGGATNFSFNTAPAATPSLFGAASAAGGTMSFTSNLFGGSTLGQTAAPAGGLFGAAAAAPAAPAQPPTVAQPAYGAFSSLPAVPDAKVGITTRGARTGSISSGASKASPLLSLRATPVRYGASVRARSEQPPSLGGAAAAAAGGGLVGVLGATGRGPVVGGAAGATSDLLTPQAPGSAGAAAAAAAGGSGLLPLRQNPHRLFIAAPPPSTEAAGGSSFLSPARPVSAHRGGGATPPDGHDGHLHSHHHDQEDRYAETPAGARTGGSGLNGYANGYATGGGGAAASGPAFHDAPPSEAHLPRLGRLVSEGYTFSPNVDELRLLHSQNPANLAAVSNFTVSRAGVGQVRWVVPVDVRGLALADIVSISYGEVACYPDAATKPPQGQGLNKPAELTLYGVYRKDKETGALIKDGPRGQAYEKALRQMCGRMGAKFVSYKLDGGVWKFEVEHFSRYGLLDEDDEFDDGEAAAAAPPARAPRGGEEGVGEAPGGARPPRGGRLGLVGGDGEEGAGNVAAGVAASPAAGLVGRGLAGTGLGGFAFGGGPAASAAGRAAGAMVVAAMPEDSGMEPSVGPRKLLGGEGGLGASEATSGAAGGGSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WG89</accession>
    <name>A0A835WG89_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008596</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000026">
        <property type="protein sequence ID" value="KAG2446611.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WG89"/>
    <dbReference type="OrthoDB" id="544942at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="126"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="245"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="133"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="253"/>
            <end position="262"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2446611.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="335" mass="35564" checksum="8AD89689705FB40C" modified="2021-09-29" version="1">MAPTTLGATTEAACANELPVEAEPDGDWVEVRHGPHPKKFALTETQAAEVAAVQACLEATARKEESGAWERLAPYIAALPHAVQRALIPKPGEEAAAKARAAKRTEKRAARKLNDRARVLVTRVRGGGRGGRRQYAAPAAAPKPSKPTAPYATLRWPPPSVVTAALKGIPAPGAQQPQPKKKAVAFVVHTPRDPAEYAYDPEPEAAGSSGGGLVEPYYLELSEEYEEKLVKGARGAKRHAYAMGKTPAGASHHPGHGHKRGGRAGGLVLRPIAEADGSFAVRIAHPSEKRLQGVRPNGFAAVGEGRARRQLHRSSAACRATCKADVPLVQLWPYL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WG94</accession>
    <name>A0A835WG94_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="6">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_000150</name>
        <name evidence="6" type="ORF">HYH02_008255</name>
        <name evidence="5" type="ORF">HYH02_010266</name>
        <name evidence="4" type="ORF">HYH02_011468</name>
        <name evidence="3" type="ORF">HYH02_012983</name>
        <name evidence="2" type="ORF">HYH02_015313</name>
        <name evidence="1" type="ORF">HYH02_015364</name>
    </gene>
    <organism evidence="6 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000158">
        <property type="protein sequence ID" value="KAG2423162.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAEHOD010000141">
        <property type="protein sequence ID" value="KAG2423482.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAEHOD010000067">
        <property type="protein sequence ID" value="KAG2432412.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAEHOD010000049">
        <property type="protein sequence ID" value="KAG2436530.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAEHOD010000037">
        <property type="protein sequence ID" value="KAG2440688.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAEHOD010000025">
        <property type="protein sequence ID" value="KAG2446689.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="EMBL" id="JAEHOD010000012">
        <property type="protein sequence ID" value="KAG2450046.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WG94"/>
    <dbReference type="OrthoDB" id="534186at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009007">
        <property type="term" value="F:site-specific DNA-methyltransferase (adenine-specific) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009307">
        <property type="term" value="P:DNA restriction-modification system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008593">
        <property type="entry name" value="Dam_MeTrfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052055">
        <property type="entry name" value="Hepadnavirus_pol/RT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050">
        <property type="entry name" value="REVERSE TRANSCRIPTASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33050:SF7">
        <property type="entry name" value="RIBONUCLEASE H"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05869">
        <property type="entry name" value="Dam"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2423162.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2423482.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2432412.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2436530.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2440688.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2446689.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2450046.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="145" mass="16435" checksum="C0B12F51BDB49DEF" modified="2021-09-29" version="1">MEERDDYRVHWSYFRRLEAWFGPHDVDLFASAGNTQLPRFFSRFFCPGSSGVDALAQPWGGLNAYGCPPADPDFLLAVVQKLREERAAATLIVPYWPAQPWWPLLMELASRVVFLPSSTEVFTLAHRGPSCGRLPPWQVAAVRVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WHZ8</accession>
    <name>A0A835WHZ8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007436</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447511.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WHZ8"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="120"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="139"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="54"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="67"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="143"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="153"/>
            <end position="165"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2447511.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="228" mass="23445" checksum="3669C5B1948A1EB0" modified="2021-09-29" version="1">MREGFSDLASFKSGGASPESICHTLMQAGLPLVHACVLEGALVREAEREQWYRQQQQQQQQQQQGPKEGGVAAGHGSRNGGVGPAAELRLAARTPSQDDTDAGHAHDQQPTCGGGTSASTASKGWWGAWLPSAPALLWSTQQPPQPQPPLHALPPGSATSPPGSAAAAAAAVAATCHAAASTTAPTPERRAVVLDDAAHSSVAPIAAPPTLASTCRRRHVHRPALGQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WKA2</accession>
    <name>A0A835WKA2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_005995</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2449249.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="551335at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1123"/>
            <end position="1143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1164"/>
            <end position="1189"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1252"/>
            <end position="1274"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="303"/>
            <end position="327"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="473"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="602"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="889"/>
            <end position="962"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1010"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1098"/>
            <end position="1119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1292"/>
            <end position="1332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="308"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="473"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="508"/>
            <end position="527"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="889"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1014"/>
            <end position="1029"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1098"/>
            <end position="1112"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2449249.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1332" mass="135120" checksum="B2037B6AA4FBB813" modified="2021-09-29" version="1">MIAPQSVDPTADAVDGASPHRPLAPVPPYSSFIRYRTWFAKFPGYHPSQLTPGWQERLRLLVAALNGGDDGGGEPAAGEPRQQQEEPSHAAHGPLRGHGDATALAAAAVAARASSTQGQHLRVRGRTAASQGPGACSAACGGSAGCVRVAGMYVREGCIELLLEEEVEDWQREWEWGSGLSTESEEGVQALQGAETPAPALQRLLLLPQEAEMQLVAAAASDRASDRPPALQGGAQQQARAVAGAHASTCTTDTGGSGLVAAVVGAGAGAGAGAACDESAADGSSAELDISRWLAAAVAAAAGGQSGGNSSNTHCSNGSADHSASETGVPRRLLAGTLPDNTVTEPAGVAPIVASPIDDTYPGDTYLDRRLPAAQPQPQALARVQALSVHALAQRGRTPELAQEPEPERPFVLRGHVVGSGSGDADRMRTLVTVGFTRAAGADGSGAGGGAGEPVVDEDELIAVIVAALVEQRNEGDRRRREQERQLHERQQPQQQEQEHGQGRRLEQQAARQPPAPAATAATAPGRVVRAAAPAAAAAAETVDEGERARAVVPPPRVPPAVAPTLLAGCPLGAVTVGPRVLLVPPPPLPSLLAAQLQQSSVAEGGGLPPPSGLGPESATDSAVPPLLPLPRSRGVSPRSRHQRLRLTCYPVSRRLATTTAGAAADAADGVSDSPTTALAPTAAGSTHIDTGQLQVHVRSRGAYLRSSVAWQQQAPVRGGEAVAAAVAASERRVWRPQVAALELQEPHLQPGVAMLDVRWRGVPCAAVPLVLTSDPELARELAVAAAAWPRSADELDALLLDFGTWEFYVADMSAMAAALAEAAAAAMEAAAEARAPLPRLPPPAPLVVTLGRHLLGYATVAGWRRVAARLRADLSWMGLGEVARGVPEVPEAPQEPGAAGQQQATVTASAAAAAPAPPVSSTAGTGGDVSPGVDTAAGGLHSASEAASGTPADSRGSGSGSKQGLLDCSELLCHAGEDAGAVTVTAGATLCGPMSCGLGSCAAAGGGGGVNPGAGSSSRSSSSGSRAGEWGGSGKCEGRRKGAPDPGAQDKGGTHDDVKDHLQFADAVAMQQGHMRYFDLACMVLLGLRTLAQAASAAGSSGSGSGTSSSGAPPPPPSPHSAGWVLLVLAVSTFAGVLSTLARPMLSAPAWAALERRCRLLRYYCYAVAKAMVFAGLGWPPGVSAYLLTPGMLLLEGAMVQPREGLVALLVMNTASFAQIAQKLSRERNAAAAAAEREASPLFGVFADREAVASAALIAGRTLLLGVATNLLFNAYVRRLYARRHADAAAHRRTGTGAGSMASAKEYDSGGSGGGGGRQAAHVTVSSQATR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WKB6</accession>
    <name>A0A835WKB6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005774</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000015">
        <property type="protein sequence ID" value="KAG2449020.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WKB6"/>
    <dbReference type="OrthoDB" id="547231at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0022900">
        <property type="term" value="P:electron transport chain"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006885">
        <property type="entry name" value="NADH_UbQ_FeS_4_mit-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12219:SF8">
        <property type="entry name" value="NADH DEHYDROGENASE [UBIQUINONE] IRON-SULFUR PROTEIN 4, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12219">
        <property type="entry name" value="NADH-UBIQUINONE OXIDOREDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="294"/>
            <end position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449020.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="423" mass="44390" checksum="D2097A6A74A5623B" modified="2021-09-29" version="1">MPPLPTLWDPAGAVDKLPQPFRMIDKVLADIVEQVVDMIGTREAQRRAEDASRVDLTFAPHAVMEVAPETSCFLPIGIAGIAAVAMPDGELQVRSARDPSVCFSDRTHTSQVTAMEAGMVVSTSGRLLAAASRTTLTLYEVDIKSCEISLLAAVPLPADPEDSSPPVRLHWSDNLGHLAVCRRSGALALFSLVLPPPNVSLESVGAFVSLSLKAFGETRVEELLRVPAATVRAFCLGSASVGPSNLVWQLQQRPDKSPHSDRYHKSARGAYVWWEGANRLLLLDFEAAAGASSGAGGAVVAPPEAEASAKPGAQGTSKPSTPATKAASSKSVAPLGEASSLLTAAPAAYAGPERPPEVPQIAPMARDWLLPHDVTAAATTSDHKTMAWGLADGSVVIWDDRSCCSTKNVTALLLGFAAAYASY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WLA4</accession>
    <name>A0A835WLA4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">PPM-type phosphatase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_005659</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449516.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WLA4"/>
    <dbReference type="OrthoDB" id="10264738at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004722">
        <property type="term" value="F:protein serine/threonine phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00143">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.40.10">
        <property type="entry name" value="PPM-type phosphatase domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015655">
        <property type="entry name" value="PP2C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036457">
        <property type="entry name" value="PPM-type-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001932">
        <property type="entry name" value="PPM-type_phosphatase-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47992">
        <property type="entry name" value="PROTEIN PHOSPHATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00481">
        <property type="entry name" value="PP2C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00332">
        <property type="entry name" value="PP2Cc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81606">
        <property type="entry name" value="PP2C-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51746">
        <property type="entry name" value="PPM_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PPM-type phosphatase" evidence="2">
        <location>
            <begin position="1"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="335"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="355"/>
            <end position="371"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51746"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2449516.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="408" mass="42438" checksum="6019B31F1FD1184E" modified="2021-09-29" version="1">MASPKEVEGFAEVVRQAIVETFVRLDNDWIAVGHMSGTTVTATIVIGYLLTVANIGDSSAVLDTGCSILELTGSHRIQSNPEEQTRLRGAGCTLAPLGFHLQGPARQGELGVGPLRLWPGGLCVSRSVGDLDAGPEVVPLPHIRQVLLPSNGARIIVCSDGVWDLMSLSKAVKLCRFKPASAATAALMGAVSRDLRLLDDASIIVVDMLPSDATSWPTVALKANPKPEKSGGLFACFRPELDEPDSRDVHSSAPGHLAFLADLDSLRVYPQMRAALQRTQIQHLATVLNNAVGGKPGIDYTMHGANKVSLYRGYVENGMPRTNSSSTAVADVASEGANHSNHSAHSAGALFSDSQGGGGKSGSQHGGSGGGAAAVLPYSASVGHNEVDSPVIAFNSVPDRQSSGLAMA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WLB9</accession>
    <name>A0A835WLB9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">RING-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_006239</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000016">
        <property type="protein sequence ID" value="KAG2448890.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WLB9"/>
    <dbReference type="OrthoDB" id="8062037at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043312">
        <property type="entry name" value="AtBBR-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001841">
        <property type="entry name" value="Znf_RING"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47530">
        <property type="entry name" value="E3 UBIQUITIN LIGASE BIG BROTHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47530:SF4">
        <property type="entry name" value="E3 UBIQUITIN LIGASE BIG BROTHER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13639">
        <property type="entry name" value="zf-RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00184">
        <property type="entry name" value="RING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50089">
        <property type="entry name" value="ZF_RING_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0862">Zinc</keyword>
    <keyword evidence="1" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="RING-type" evidence="3">
        <location>
            <begin position="127"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00175"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50089"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2448890.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="172" mass="18797" checksum="82E76B5C3BF1A320" modified="2021-09-29" version="1">MLDRGTSEQHQLSREETVQEEHGAELTDEELARRLQEEEDQATYQAMAGYGSYGLDEVLQEEGEGIIGTGSEPEQSAMDLTYEDMLALGDLAGKVSKGLPPEVLARLPVEAVGSLKSGGGAILLDRCCICQVEFEDSDSATALPCRHCYHSECVRQWLQQSKACPVCSKEVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WLC9</accession>
    <name>A0A835WLC9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005526</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449374.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WLC9"/>
    <dbReference type="OrthoDB" id="10563747at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="10"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449374.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="345" mass="36330" checksum="F13084C9C1F9FA58" modified="2021-09-29" version="1">MQEPSTSSCGLSPKTPQRHLYRPSWPAPRSILRSSCQLQGTSSVAPTTAGSFGVCCPSAASTSGLASPSQARHLPGASTSPTFSYPAVNAPASEDDNVLLIPPALAAAAAALSPEDAALFDADMRDLEACGLVEWQSADDLHAAALVRLAGSTDWARLAAGLNASPVGWADEEAADRLLLSPQWREAMAHQQAHAATAAGGDAVSAMQAAVAKLRQEQDGAAEEQVEQEPQLAGTLSSAFSMSHEDRLLFGADMADLEAFGLVDWQVADLEQRVTSTRLQRLSEQMAQMLADMQAEGRQRQQQQQWQWQGREGMQQRGGSWCGVEACGAPGAPCGAEAPRLVAVV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WMF4</accession>
    <name>A0A835WMF4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3 9">Glucose-6-phosphate isomerase</fullName>
            <ecNumber evidence="3 9">5.3.1.9</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_000248</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="8 9">
            <text>alpha-D-glucose 6-phosphate = beta-D-fructose 6-phosphate</text>
            <dbReference type="Rhea" id="RHEA:11816"/>
            <dbReference type="ChEBI" id="CHEBI:57634"/>
            <dbReference type="ChEBI" id="CHEBI:58225"/>
            <dbReference type="EC" id="5.3.1.9"/>
        </reaction>
    </comment>
    <comment type="pathway">
        <text evidence="1 9">Carbohydrate degradation; glycolysis; D-glyceraldehyde 3-phosphate and glycerone phosphate from D-glucose: step 2/4.</text>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the GPI family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.3.1.9" evidence="3 9"/>
    <dbReference type="EMBL" id="JAEHOD010000012">
        <property type="protein sequence ID" value="KAG2450146.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WMF4"/>
    <dbReference type="OrthoDB" id="5831190at2759"/>
    <dbReference type="UniPathway" id="UPA00109">
        <property type="reaction ID" value="UER00181"/>
    </dbReference>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0097367">
        <property type="term" value="F:carbohydrate derivative binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004347">
        <property type="term" value="F:glucose-6-phosphate isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048029">
        <property type="term" value="F:monosaccharide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006094">
        <property type="term" value="P:gluconeogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051156">
        <property type="term" value="P:glucose 6-phosphate metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006096">
        <property type="term" value="P:glycolytic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd05015">
        <property type="entry name" value="SIS_PGI_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd05016">
        <property type="entry name" value="SIS_PGI_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000018">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000031">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.10490:FF:000048">
        <property type="entry name" value="Glucose-6-phosphate isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1390.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.10490">
        <property type="entry name" value="Glucose-6-phosphate isomerase like protein, domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="HAMAP" id="MF_00473">
        <property type="entry name" value="G6P_isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001672">
        <property type="entry name" value="G6P_Isomerase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023096">
        <property type="entry name" value="G6P_Isomerase_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018189">
        <property type="entry name" value="Phosphoglucose_isomerase_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046348">
        <property type="entry name" value="SIS_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035476">
        <property type="entry name" value="SIS_PGI_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035482">
        <property type="entry name" value="SIS_PGI_2"/>
    </dbReference>
    <dbReference type="NCBIfam" id="NF001211">
        <property type="entry name" value="PRK00179.1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11469:SF1">
        <property type="entry name" value="GLUCOSE-6-PHOSPHATE ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00342">
        <property type="entry name" value="PGI"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00662">
        <property type="entry name" value="G6PISOMERASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53697">
        <property type="entry name" value="SIS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00765">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00174">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51463">
        <property type="entry name" value="P_GLUCOSE_ISOMERASE_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="4 9" id="KW-0312">Gluconeogenesis</keyword>
    <keyword evidence="6 9" id="KW-0324">Glycolysis</keyword>
    <keyword evidence="7 9" id="KW-0413">Isomerase</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004926"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006604"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00011952"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022432"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023152"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023235"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00029321"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="RuleBase" id="RU000612"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2450146.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="584" mass="65625" checksum="28E4560E9715DE9B" modified="2021-09-29" version="1">MIHTTSNKKGELVSELPAWQALKEHVNEIEKTHLRDLLHDEARCMSMIKECEGMYCDFTRQRVTQKTLELLFELAEQSNLRGKINAMFNGEHINSTEDRAVLHVATRAHRNQKIMVDGRDVVPDVWEVLDKIKAFSDKVRNGEWLGVTGKPLKNVVAIGIGGSFLGPLFVHTALRTEPVAMRCSRDRRLRFLANVDPIDVARALDGLDPEETLVVVISKTFTTAETMLNARTVRSWLTSRLGPEAVAKHMVAVSTNLKLVKEFGIDPENAFGFWDWVGGRYSVCSAVGMLPLSLQYGFDLMQEFLAGANNIDEHFKNQPYQDNLPVLMGLLSLWNVSFLGHGAKAILPYCQALSKLAPHIQQVDMESNGKGVDINGVRLPFETGEIDFGEPGTNGQHSFYQLIHQGRVVPCEFIGIVRSQQSVYLKGEVVSNHDELMCNFFAQADALAYGKTPEQLRSDNVPDYLIPHRVFTGNRPSMSIMLPSCTAYTVGQLLAIYEHRIAVQGFIWNINSFDQWGVELGKVLASKVRTVMNSARTRDRKILPQDGFNYSTTRMINKYLEGKTQVLYPEGHDSFPIDMLRGVQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WNH8</accession>
    <name>A0A835WNH8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Cyclin-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_004969</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000011">
        <property type="protein sequence ID" value="KAG2450468.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WNH8"/>
    <dbReference type="OrthoDB" id="10264655at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016538">
        <property type="term" value="F:cyclin-dependent protein serine/threonine kinase regulator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006357">
        <property type="term" value="P:regulation of transcription by RNA polymerase II"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd20533">
        <property type="entry name" value="CYCLIN_CCNL_rpt2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.472.10:FF:000031">
        <property type="entry name" value="cyclin-L1-1-like isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.472.10">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013763">
        <property type="entry name" value="Cyclin-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036915">
        <property type="entry name" value="Cyclin-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043198">
        <property type="entry name" value="Cyclin/Ssn8"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004367">
        <property type="entry name" value="Cyclin_C-dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10026">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF036580">
        <property type="entry name" value="Cyclin_L"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00385">
        <property type="entry name" value="CYCLIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01332">
        <property type="entry name" value="Cyclin_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47954">
        <property type="entry name" value="Cyclin-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cyclin C-terminal" evidence="3">
        <location>
            <begin position="23"/>
            <end position="135"/>
        </location>
    </feature>
    <feature type="domain" description="Cyclin-like" evidence="2">
        <location>
            <begin position="27"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="130"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="406"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="168"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="257"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="293"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="325"/>
            <end position="391"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="SMART" id="SM00385"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01332"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2450468.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="406" mass="44619" checksum="9447F1B573044553" modified="2021-09-29" version="1">MKERVITYERILLKTFGFIIHCVHPHKFVNSFVHSLEGGDELQQLAWNMLNDSLRTTLCVRFKGHVVAAGAIYLAARRLQVPLPSSPAWWEAFKVPTDQMVEVVLALDALYRRPKAHYIEVNPEVLKQQQALSGPAGAKQLTPGPGELGNDSPAVAQDSSVIRGGPDLASQQLGGPPGPGTAAAVVAGSTAAPPGNAAEMLAAAVALAQQRLQGSVALASGINAAQAAAVAAAAQAAQAAAAAAKPDPDTVSTLHQGGDGQANGGGPATSAVEGGAVQSRKRSRSRDRSQDRNRRRSRSSSRSRSRSRDRHRNGSRRDHRSRSRERRDRDRDRERRDHRDHRDRDRDRERERENERERERERRDGGRDRERDRERGRERGRDDRDGADRGDLPAPPPLPPRPDRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WPI2</accession>
    <name>A0A835WPI2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_004294</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000009">
        <property type="protein sequence ID" value="KAG2451024.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WPI2"/>
    <dbReference type="OrthoDB" id="532838at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="68"/>
            <end position="87"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="141"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="141"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="174"/>
            <end position="188"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2451024.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="403" mass="39704" checksum="C66DCDC293DB0E9F" modified="2021-09-29" version="1">MSQLFGLVRRASNARSHIFALAGATAAAYFGLSESEQHLQHRHESQSRPGAAAQRITLPGLTTTALADAPPRPAAAAPTASPSPSSASAAATYSISLTGYEDVRDANGFVASALEKALRGGGRGGGRDSPLAALLGITPAGATTSSTTSSSPSSSSSSSSSSSADITSASGSGAASGSGSGSGSGSGPGLAAAAGRAAAPSGASVLSFGESPGPAAAAAGIDPAAFYTLLAKQPLHEKVLILDELVDSVIAEAEAGAEAAGLAVGLLGGGLACYALVGWWTDLALPGAGTVACSAVAGAAGHHRAKVAAQRTRSRFLSALLSQQQPANHPTANHPTANRPNTGLSNSFLAYLAAPTLAEKQRVAGDTPPAAFFADFYTALQPLLKQSKLEADAAGRAVLVQLD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRM1</accession>
    <name>A0A835WRM1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">NECAP PHear domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_003374</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452351.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRM1"/>
    <dbReference type="OrthoDB" id="10265489at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030125">
        <property type="term" value="C:clathrin vesicle coat"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006897">
        <property type="term" value="P:endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.29.30">
        <property type="entry name" value="Pleckstrin-homology domain (PH domain)/Phosphotyrosine-binding domain (PTB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012466">
        <property type="entry name" value="NECAP_PHear"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011993">
        <property type="entry name" value="PH-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847">
        <property type="entry name" value="ATP-BINDING CASSETTE ABC TRANSPORTER-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12847:SF9">
        <property type="entry name" value="NECAP-LIKE PROTEIN CG9132"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07933">
        <property type="entry name" value="DUF1681"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50729">
        <property type="entry name" value="PH domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="NECAP PHear" evidence="1">
        <location>
            <begin position="2"/>
            <end position="96"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF07933"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452351.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="103" mass="11534" checksum="11214F55135301F6" modified="2021-09-29" version="1">MIVRLSDQESAELFAECPLPDDGTPLTTAVEPVVDSSRYFVLRVVDKETSKHAFIGLGFRERTDASGFTTGLDEYRKYLLRKKEAEAMKAEHEAQENGEEAGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRP8</accession>
    <name>A0A835WRP8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_003152</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452118.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRP8"/>
    <dbReference type="OrthoDB" id="537030at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125">
        <property type="entry name" value="LP07818P1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48125:SF10">
        <property type="entry name" value="OS12G0136300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="57"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="211"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="688"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="57"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="211"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="703"/>
            <end position="728"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452118.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="758" mass="81092" checksum="9931378A9B7728FD" modified="2021-09-29" version="1">MEEGEKLQKELNDIGAEIARVSAQAESAKDAEDKRYFREKELMLRKEKLMLLEARGAAAGPGPGSTAADGSRPAAAGPPACKLRLRQDVLNTDLYFFEPMDTSSAAASAASPGVSSGSFFLDPEGKQKAELEDWLGLAMDLHGKGKPILPLIINGQVKSGKSYMLNEVLPAVANTYYCSASAASAASDSAANASAASVSAASDSTASDSVSAASDSAASDSDSDSQQQQAGGGGAMQQLSGPPNFLRVNCLDCDRSSGVGGFLKELLVKLKRSAADERLYAAASTPVPSDCSAGTMADAIQDFMRRLPRDRLNFLLVDEAQSFYLMARPAVFGDGAPRDPTLDVEAVLHMRRILKGLLLDSPHWVAWAVTGSSMATLWANVAATPTNGFSLIMHHRRLNLSPTMPLEALQVAWAQLKAQAKTWHPVRPLPKDLAWQSPPQVAMLAYLCEEWRYSRTAGTAAELVEQTMTQKLIPEVLADLRMVLQVLGQPASQLLLLRELLDPAAGVEAAKLPPAFKVLLGSFATTRDDGTLFLDYPLLAQVLQAVTTESGELLEAITAVQSISSKMFRELVVLGECCKSRSFDSLEDLHGLLREMETALALKPDTLLGTDWFTQALDHRCNSRGGKANFEKTHRAQATEDAKVGLRWFHALLRNVLCHGYISEQRQALQAYPPQLAALHSSGRVGKELTKTFDSPPPTRSKAPVASAAAAPRSAAAPRAQLQPPGAGPAVRPIVSLHLGKRLGRAAGAAVIPRRYVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WS06</accession>
    <name>A0A835WS06_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Molybdate-anion transporter</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="10">Major facilitator superfamily domain-containing protein 5</fullName>
        </alternativeName>
        <alternativeName>
            <fullName evidence="11">Molybdate transporter 2 homolog</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="14" type="ORF">HYH02_003381</name>
    </gene>
    <organism evidence="14 15">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="14" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="14">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="1">Mediates high-affinity intracellular uptake of the rare oligo-element molybdenum.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cell membrane</location>
            <topology evidence="2">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="14">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452359.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WS06"/>
    <dbReference type="OrthoDB" id="263957at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015098">
        <property type="term" value="F:molybdate ion transmembrane transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006811">
        <property type="term" value="P:monoatomic ion transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd17487">
        <property type="entry name" value="MFS_MFSD5_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008509">
        <property type="entry name" value="MOT2/MFSD5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516:SF1">
        <property type="entry name" value="MOLYBDATE-ANION TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23516">
        <property type="entry name" value="SAM (S-ADENOSYL METHIONINE) TRANSPORTER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05631">
        <property type="entry name" value="MFS_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1003">Cell membrane</keyword>
    <keyword evidence="8" id="KW-0406">Ion transport</keyword>
    <keyword evidence="9 13" id="KW-0472">Membrane</keyword>
    <keyword evidence="15" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6 13" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="7 13" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="4" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="6"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="97"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="129"/>
            <end position="151"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="187"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="226"/>
            <end position="245"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="304"/>
            <end position="328"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="340"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="367"/>
            <end position="386"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="416"/>
            <end position="436"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="13">
        <location>
            <begin position="474"/>
            <end position="494"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="12">
        <location>
            <begin position="56"/>
            <end position="80"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00003019"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004651"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00021242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022475"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00030646"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00032555"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="EMBL" id="KAG2452359.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="514" mass="53482" checksum="89D76CF1BBF0F421" modified="2021-09-29" version="1">MDLFYVVLFGTLVFVAVVLHLSGTDSSSCGSSGGGGSGGGGDAAAGGRACVEGGSDGGGSAGTGSTGGGSGAGSGSGAGGPVSEAESKRFRLFRNNYLIVFCLMMAGDWLQGPYIYALYEHYGYSVGDIGHFFIMGFGSSMVFGTVVGALADITGRRAASLAYVASYCLSCATKHSPRYGVLMAGRALGGVSTSLLFSVFESWLVAEHNRRGFPEAWLAETFSQAIFLGAGLMAILSGLLGNVLVEDLRLGPVAPFDAAIVVMLGGGALVAATWPENYGDAAARRSVLAQLGQGLAAIRTDQRIALLGAMQSLFEASMYTFVFLWTPALSPRGEKIPHGLVFSCFMTACMAGSAGTGLLIRRHPPQAYMGAVYAAAAVSLSVPLIYHTERRDPSEGGSSLRDNGAGGLSVAGKLQLLAFCGFEACIGVFWPSMMALRAHYVPEELRATIINIFRIPLNLFVCVVLYKVSAFPLSVMFGVCVGMLLLCLLCQMRLNDLTGAKDKPSLADLAAHDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WSQ2</accession>
    <name>A0A835WSQ2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_002274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452936.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="248495at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1078"/>
            <end position="1360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="15"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="127"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="760"/>
            <end position="815"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="966"/>
            <end position="985"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1118"/>
            <end position="1146"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="510"/>
            <end position="541"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="93"/>
            <end position="113"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="127"/>
            <end position="156"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="169"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="214"/>
            <end position="231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="236"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="249"/>
            <end position="265"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="346"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="363"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="760"/>
            <end position="775"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="783"/>
            <end position="793"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1126"/>
            <end position="1139"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2452936.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1362" mass="138489" checksum="A441A7DE01196E31" modified="2021-09-29" version="1">MAPVRSVGDLTAFTAASGGGAGSCVDPASLPPVKVETTRRHNAGTEGSNSAGYSASATSSLQQGGGGSSAAQGAGGSSAAHGGAGSSAMGPTPGSSAAGPTLGSSAAGPAAGSSAAGETAAISTAAGAAGAPSLTGTDRTQDSTATADGAASKAAGGFMFGAPRMKEHKEKRRKEAKRAKSQSSSNASSNPKHILGSEGQPPTEGSKGQSIGAGSSGPGPTAGAGTSGGGVLPIVGSSSMVPPNGSSAMMPSNGSSDNMMSSSTNLQADMASPTVGSTAGNTVMLEGSSGANPVANFKSIGRSRAPRTAAGSKTPGEGSSGRGSSVPTPGSGLAAPVEGAPPPVPEGEEEGESQGEGDDDSSSPRSSSDHLSIMSPPEGSDVENVLQLICNIFQLPVALVAAYRSANIFIRSTALKLTDDDQWRYSLAQWSMLNVHDLRDVLVVPDATLDDRFRNQYCVANEPRLRFFCASPLRSSTGELLGTLCMADFKERIFEPTNLLVVNNLQSLVIRQLERDMALAAERLENEVATEQLQQEMMRALDHFEKCIMFVDTSKPGWEVLYTNLAWEHVTGVPRVHVLGRSLQDFFMALGGASLDWSSTAAELASRSEFTVNRVAVRQKPDKLVSLHLRLATNQANGELEGLLPKGLPAWVKARGSEAHNYFVFVEEAQGGSTVYEALAKHVEKVPGLELSHLLGKGGFGSVYYGTWNGLPVAVKMIDNRLTKTNTEGVSLEALMGQELAHPNIVKTIKYVMRNQLNASSVSGSNSRGPGSSHQRPGRSGQPPGSQLNSRNPHVTPPVGSRHGSRNPPHGTDPAMNAAAAALVNARGATGATSANPGMMQYLTSANPGTGPMTSAQIAAAADLTSASGMNINNMQLQHMVSTMTSDATTVAGGGTDTIGSSGMPGRAANLVGSMSAGTGHGSTPLTHNPAGVAAAAAAAAAAANAAELARHVAATATAAAAAGQPGGKAAAADGDESTTTASGVTAVGPASVHASSASTAAGPPSIVSAGVPANPVSPANLSHSASATALHAKVGSSGRTPTSAQRTAAAAAIAAAPPLPAVLPPLAAAAANPAATTSITAAYPPGAPPPNLTTEQQHAAMTSRFSMAFSTITEGGDVLVPEKGSPSTSTDSHTQRPNVGSAGSGEDMGEVWIIMEFCDRGSLQDALDRGALKLRKPSGEMGETHLPMMVATACEVASALQYLHDRGIVHGDLTAWNVMLCTAADPAADRSGRNFTAKVADFGLSRNLDVRSKIKTRTYGTISHMPPECLISGIISKATDVFAFGVLLWQMYTGLRPWAGMNHGQIIYNVGMKNVQLLFPPGTPPAIADLSSSCTRTDPNTRPSFGEIMEKLGNIRASLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WT02</accession>
    <name>A0A835WT02_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_002199</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452854.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WT02"/>
    <dbReference type="OrthoDB" id="553077at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="42"/>
            <end position="125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="167"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="218"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="309"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="411"/>
            <end position="662"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="917"/>
            <end position="969"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1068"/>
            <end position="1096"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1143"/>
            <end position="1168"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="60"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="76"/>
            <end position="101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="170"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="316"/>
            <end position="325"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="326"/>
            <end position="339"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="450"/>
            <end position="503"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="549"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="565"/>
            <end position="622"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="636"/>
            <end position="647"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="938"/>
            <end position="948"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1144"/>
            <end position="1168"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452854.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1168" mass="112858" checksum="088B042CE19B543A" modified="2021-09-29" version="1">MGCSKKLKARSLLRAYARALSSRGDRSDDAAARMEAFRVAVRMTSDGRDSDGGGPDEAPDGLPALGPPAAGRSRGAAGGGGGGDGLDGLGDLQGVGPGGTAGLEPGALGSGGGGGPLTRALPGLSGGAGSGRGGLPGLALAAGGGGPLDGDVAARIAGAGLLSGSGPCRTGSSGDPCNNGPNPTTHPSSPDRSNPHADHAAAAAATAQLHDLQQQHEGGIYSSRPGSNGTIIGGAAARGGDGGVAADRNGTAPPPPLPPADRLVAALMQGTGVEDTGRLAGDGAGVGPAAARYKQMAAGGGHMNGPGGVNGGANGGDAQDAWGPLAPGGSGRGGAGAGLRNGQTGEGILQELQARGVPPQLLQQLLAKGVSAAALQAVLLEARMNGADGGMDEPGPAAAPLPLLAGAHELPPRELAPPRQMLDGPGRSASQLERSREDARATPPPPQRLLKLEREAQSGHDEAQRTADGAEPRVRVKAEALEDSGKAIAEDGNGRRQPPDAHDGAAAQQPTGSREDSGTGPSRQGVGNGREAVRAAEADQGGRAAKAQPQLSQGYEQQSLDSSRRGAGPAGSSRPQQQQQQQQQQLPVLAAGTIEAAARARGAMAAEWEGEASGNGNGAAASIRVLRGSDDDRLDGSSLGSRGPGPLQAAPRPPLGDLPSPMADVDARDSSSVLRALAAAVAANGGGGGHPLQALAAALTANGGSAGSLGGALASLAAGRDGGGGGGGRLEQLAAALVNGGSGGAVGPAGPGAGEQLGRPGGQGLAMLHGSGGGGGGGGGMLGTLLAEAQRGRAAAAGLGGDAEETALADLIRASLAEAEAAEAARARAANRALEAAARLMQVRQARARAGVQLPPESMLANALASARTRMAGSSGSAGGDELLSRLALLQSLQAGDGGGGAPGAVDLAAMLDAARGGGAAGSSGTNGAAGGGPKRHALSDDEREQLPPRKRHALGYSDDGPLLRSRGGGGNGVPLLPLHHLQLANAVGAGTGPGGHWGGDMLDAPPPPPPPPQQQQQFLADMRGLMSGLAATGGGAAGGRGREQQDMLDMLRSRAAAALAASGVPAGAGGGLGHLRGPPAGARGLLQEEEEDGPGPAAVATAMAAEAAALRRKGATGLLESQDSLGEMAQTLLGFSQMAAQTLGGGEPASGAGGGGGGGGGRKGQRW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WT21</accession>
    <name>A0A835WT21_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">EGF-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_002267</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 47 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WT21"/>
    <dbReference type="OrthoDB" id="1924787at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016757">
        <property type="term" value="F:glycosyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.10.25.10">
        <property type="entry name" value="Laminin"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000742">
        <property type="entry name" value="EGF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004263">
        <property type="entry name" value="Exostosin"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040911">
        <property type="entry name" value="Exostosin_GT47"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062:SF376">
        <property type="entry name" value="EXOSTOSIN FAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11062">
        <property type="entry name" value="EXOSTOSIN HEPARAN SULFATE GLYCOSYLTRANSFERASE -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03016">
        <property type="entry name" value="Exostosin_GT47"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00022">
        <property type="entry name" value="EGF_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="4">
        <location>
            <begin position="1"/>
            <end position="29"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033041413" description="EGF-like domain-containing protein" evidence="4">
        <location>
            <begin position="30"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="domain" description="EGF-like" evidence="5">
        <location>
            <begin position="50"/>
            <end position="61"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010271"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS00022"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2452927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="575" mass="64661" checksum="4D85769E983AE887" modified="2021-09-29" version="1">MRGNRKVATAAALLLLGIALLPLLQPAIGQKTCPEGCSKFGTCNLELGRCDCPWNYTGDACQTHNPAGFCVKRLGVDNPINTCKDGHPTLCVNACNGRGDCKGGFCHCKEGYFGTDCALSYNDQGKIEVLAGLNYRLNKRGPKIYIYEVPPEYHVKRDIHKVDRPPLQLAFMERILSGGHRTHDPEEADFFYVPGSARDLKKAFLLQPLLAYISTTWPYWNATGGARHVMPAEGDVGTCELPLKVRLFTANVTWLQFWGMYDFHPHWTQIFHNRIPCMVPGRDIVVPFMAMSSHDRFVIETPLHPRNQKRNRTNVFFFAGGVCGSGNKRALPPHCTYYKQVRYSGGVRQAVYLHFHNRTGWRVVPGTDDYARDYASSRFCLAAAGGGWGKRGIVAAMYGCIPVAATDMLYEAFEPEMDWGRFGVRISQAEIPQLADKLEAFSEAQVARMQERTACAAQHLHWSTNLGGIMGETGEFDAFNTIMAILRMRRKRPDLKPEQYYDTDEDFRNFIDCKPYDPKAAAPPLCTMFISPLYTKFDDTCPAKHFRYYMRRKMGPPGGAICVDATDLASCRRFD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WTQ7</accession>
    <name>A0A835WTQ7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_002631</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452385.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WTQ7"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="27"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032824977" evidence="2">
        <location>
            <begin position="28"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="94"/>
            <end position="115"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="115"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2452385.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="512" mass="53088" checksum="B7818B3B44B859F3" modified="2021-09-29" version="1">MARQRLATAPALALAALLVAACVKSDGTKCGNLESAPCDLSSSYCNNVGTGSSALVYILDSGINVGDTVGIQVHDGGFKDNATTICSITVPGANENTANPAPPSPLPPSPLPPSPAPPLPNIASCVAPTVCPANTLLQQVGIPNYACSTCTAAGTCLTESTNLETSPLAFTHPNAARNYLDTASCPYRRVADTQYTALVKIETSPGTIIEVPVSADAYPLVGTSPAYTSLNAYLAAATSIGDAVAVACYTTDALTTVDKYIVIQRIATATDNYACLTCKWYNTYEVRAPQPSCSCASDTAWAFPVKAVLSTISASSLSSTTEILLPAPYNDASTLADPTNPGLTRVWWAARPEANAAAWGGYIRISGPLDSAREFEFDMCAGCAQNSLGTKGYIMGKLKVKFQPTTDGKTSVMSFVEPSAGAYTTSDALQVFQSFVAPPDLNPGSFQRYTGITPVTLPFSYGTSFSVNKVTVGPVTLGRATLATVPTSNTDGVYIAVHMNVGGGFCPGSSLY</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WTR0</accession>
    <name>A0A835WTR0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">CRAL-TRIO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_001712</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cell membrane</location>
            <topology evidence="1">Peripheral membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="2">Golgi apparatus membrane</location>
            <topology evidence="2">Peripheral membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the SFH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453491.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WTR0"/>
    <dbReference type="OrthoDB" id="1434354at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd00170">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.525.10">
        <property type="entry name" value="CRAL-TRIO lipid binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001251">
        <property type="entry name" value="CRAL-TRIO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036865">
        <property type="entry name" value="CRAL-TRIO_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051026">
        <property type="entry name" value="PI/PC_transfer"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45657:SF1">
        <property type="entry name" value="CRAL-TRIO DOMAIN-CONTAINING PROTEIN YKL091C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00650">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00516">
        <property type="entry name" value="SEC14"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52087">
        <property type="entry name" value="CRAL/TRIO domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50191">
        <property type="entry name" value="CRAL_TRIO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CRAL-TRIO" evidence="6">
        <location>
            <begin position="25"/>
            <end position="199"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="224"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="4">
        <location>
            <begin position="367"/>
            <end position="401"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="227"/>
            <end position="239"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="5">
        <location>
            <begin position="271"/>
            <end position="282"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004202"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004395"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00038020"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50191"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2453491.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="406" mass="44278" checksum="A61903665CCEB240" modified="2021-09-29" version="1">MWTDHVHWRRENNVDTILQDFHFDERDKFLDAYPQGYHKLDKVGRPVYIQLIGKINVPAIMKCTDEERMFKFHVQEYERCVKVIMPIASKLAGRKVDQTFGIMDVKGVGMSALTGDVKRMLGKFTKTDQDNYPEMLGHICIINAPAVFRMLWGIVKNMIDVRTQQKIEILGPNYMEALLKHMEIENIPEFLGGQSRGTLLDDVGPWSDPELMAANGIDVEALRRGDPAGAAPGPGLAAPTFGRTPSRLNSALGPMGSMFRTPTVGRTSLEANGAGPSAAASGPSAMLAASAAATVAQLQAIAENRSRSLQERVKVLENMLPTALERARPQAATDVSVRSAPEGSLLNRVEVLEDAVETVLLAQEALIIQAQQQAQLTETALADLRNRVATAEAKASSAKAGCCTIM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WU44</accession>
    <name>A0A835WU44_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">S-adenosyl-L-methionine-dependent methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_001318</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the UPF0677 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454289.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WU44"/>
    <dbReference type="OrthoDB" id="203237at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007213">
        <property type="entry name" value="Ppm1/Ppm2/Tcmp"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011610">
        <property type="entry name" value="SAM_mthyl_Trfase_ML2640-like"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00027">
        <property type="entry name" value="mthyl_TIGR00027"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASE YKTD-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43619:SF2">
        <property type="entry name" value="S-ADENOSYL-L-METHIONINE-DEPENDENT METHYLTRANSFERASES SUPERFAMILY PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04072">
        <property type="entry name" value="LCM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0808">Transferase</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00008138"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2454289.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="361" mass="38061" checksum="E2A19A294D9B33A8" modified="2021-09-29" version="1">MESKEAGAAAAAALAATSAFTAATSTAAAPAAANKAPVPATAPVAAADTAGSSKLGLLYAVTRGQPTNYDMLVFRTLNRELGRPNANADHLAPRLRDELMPRRSWLLKHLPGSKAQLRRTLENPLWGVPGAVNFIDARTKWFDGAVAEALADGIQQVVIVAAGYDTRAYRLGAPGVRFFEIDLPSASAAKKALVEKLKFVEDPSRLPTFVAADLSRVSLAEALAGTGFDPSQRTLFTVEGLIYYLPQAAASGLLSALSGLAASGSRAYFDFMSLDALEGRGSNFPGFKVTRKSVANKGEPFLSGIGPSREAVAAALAPHGLALREFLAPKDMVGLMLPHESWSDRKPPIASFYYYAAADKP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2023-02-22" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUT3</accession>
    <name>A0A835WUT3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_000531</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454693.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUT3"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2454693.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="74" mass="8385" checksum="4B8B239F06545102" modified="2021-09-29" version="1">MVESLQKGQEELQTSYNLQHEKLQKQDEKLQKQAALIEKLHVEKNYVGNLGHLLLAFFGYVPHSVSGAAHEKLA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WV42</accession>
    <name>A0A835WV42_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_002006</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453798.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WV42"/>
    <dbReference type="OrthoDB" id="553965at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2453798.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="130" mass="13351" checksum="432099E67499B239" modified="2021-09-29" version="1">MDFRGDLDFSAYGAARNVSLPGVLRANGTAYFPTDLPGASVMVWSKGAMGTSVLQVLNLPATLGYGAATVFSPTGSCLSNLLRTAPASLDCSAAQPNSDAPGWSCTGPVLGLANEFPGVNRLSVWLLKGN</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WV80</accession>
    <name>A0A835WV80_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_001289</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454256.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WV80"/>
    <dbReference type="OrthoDB" id="539901at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.20">
        <property type="entry name" value="PAS domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003018">
        <property type="entry name" value="GAF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035965">
        <property type="entry name" value="PAS-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102:SF2">
        <property type="entry name" value="GAF DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43102">
        <property type="entry name" value="SLR1143 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01590">
        <property type="entry name" value="GAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00109">
        <property type="entry name" value="TYRKINASE"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55785">
        <property type="entry name" value="PYP-like sensor domain (PAS domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="2" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="1" id="KW-0675">Receptor</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="455"/>
            <end position="768"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="345"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="495"/>
            <end position="528"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="17"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="74"/>
            <end position="85"/>
        </location>
    </feature>
    <feature type="binding site" evidence="2">
        <location>
            <position position="482"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023170"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2454256.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="773" mass="81910" checksum="DA032D6A29D104A6" modified="2021-09-29" version="1">MGSGSSKSRAKRGPESASGAAPLTAPAPAAIKAPAAAQHNGSSSGKAPAGVATPPAVEPASRVSTSSSAQEPAEPEHKGAEAPLNEPDRMDYLCKLGVLDTEPEKRFDDITRLCCLVFKCPIALVSLVDKDRQWFKSVQGLPVRQTDRRSSFCAWTLLPEHPEVLVVENALEDIRFRNNPLVLGSPHIRFYAGCPLVATQGLRLGSLCIIDNKPRRFDAESCNMLANMAEMVVREIEKDKLIEAQKIKSEMLYRENHQLIRALDCFNEGIMLVNMSLPSWPILFVNEAWEKATGVAREALTGDAFWTSFATGDVSPEASRVKFQAAIDAQESFSIRVFVQPAAASSSSSSGTGANPQDGGSSNGNGNGRRCLSLQFRCAHNSTVDTYMPLVGIPSILSAAPVAGGPMYYFVTLLMGAANGTAAGGTPGSADPASASQRGSAFTIINTKIDPFDDVKLGPLLGKGSYGRVYRGVWNGAQVAVKVLETMAGEGGGGGGGSMLGGGGGSGSLDGGGVSSGTGGGGGGGTGGDGEVLEAVLSASISHPNVVQTYKHCTRRSGSSATDADNEGRPLLETWMVMEFCNKGGLTDAIERGWFRKRHSLFEVDYRALILTAREVAAAMTYLHSRNILHGDLTGTNVLLTASDRDERHFAAKVADFGLSRVLQGEAVTTRSYGTITHMAQELLVDGLLSKAADVYSFGVVVWEMYTGQRPFGGLSHGQILHAITTGKQLPLGPTCPQPMREFLSRCLAPKPEARPSFAEIIDLLEELEQELC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WV91</accession>
    <name>A0A835WV91_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">BTB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_000501</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454662.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WV91"/>
    <dbReference type="OrthoDB" id="539040at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000151">
        <property type="term" value="C:ubiquitin ligase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd18186">
        <property type="entry name" value="BTB_POZ_ZBTB_KLHL-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.710.10">
        <property type="entry name" value="Potassium Channel Kv1.1, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044515">
        <property type="entry name" value="ABTB1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000210">
        <property type="entry name" value="BTB/POZ_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011333">
        <property type="entry name" value="SKP1/BTB/POZ_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB/POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46231:SF1">
        <property type="entry name" value="ANKYRIN REPEAT AND BTB_POZ DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00651">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00225">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54695">
        <property type="entry name" value="POZ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50097">
        <property type="entry name" value="BTB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <feature type="domain" description="BTB" evidence="5">
        <location>
            <begin position="743"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="211"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="352"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="452"/>
            <end position="544"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="695"/>
            <end position="738"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="352"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="376"/>
            <end position="385"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="468"/>
            <end position="491"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="502"/>
            <end position="512"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="528"/>
            <end position="537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="695"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="727"/>
            <end position="736"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023043"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="PROSITE" id="PS50097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2454662.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="935" mass="91890" checksum="5391C27C603A9EA2" modified="2021-09-29" version="1">MRAQRASVEIHFQKAGFTKGGYAQVISRAEGAQVGIGFRGTVDAVKLAGGRVDAQRLPVCQSTSKREGPRMRPLRPWFRSACYDPFTGHVLMAEAERDPAGWPRFCNVVRLDAASLVSEVVDSSAIRAYLQQYTSATLAAAASATVASTDPAVAASAAAAATAAANASAGFTHILHMASDGQGGVYFVTGDESRARCAILKLTLPEDWRAGVTSGASVPGGEGSRRSPQHATAHGKRPRQDTASSASTATTSILRGSETPDVRVSMVLPAAPSTDITGLAWDARSETLLFSTPTAIYRLPQLSSPRGGAVGGGGGGGAGPAGAGGMVAGGGCVSAATGREEGEAGAGGAAARGAVGAAGSGGSGGSGNTDSAGAQGPSGAGGGAAEGSRHSRLSEAGAAAATAAAAAAVAAVAAGSGVPVAALPSAAAVAAAAIAAIPQPPVMLLVAGKEGERAPAGGPDGNPLASGTGTGGGTAGTGDGGGTGGTASGGSEGREVNSSRGPGAGGEGAGGESGREGGASATPALDARDEDEDEESPDTPPPEVAAADARFSAIGGVCVDADSNIYIIDNGSFHDRHIYKLSCGTSGVLPVVSGWGNTGNILGCPAILDNGVLVACSDPFDNGFDNWQEWDGDERCPEGMLLLVDVGARPPMGHPSAVTCMAAAVAAAAAALGVHAMGGAAAGAFLVGGGGNAGGGSGGAKSQRNGGGSRGRRSTPPGVATTGGSGAVASTSASTGRWQPGSADLTIVVGSRSFSVHRGVIAACSGYCRQRLADSGGSTGQLDLPDADADAFALLLRWLYTGATVVPATHAQAVAELADRLLLPPELCRAAQSQVLAAVTPETVVDTLLWAERLGAMASEMLRELKSWYVHHRDQVMDVAADSVRQLEDKSPALARELLEEAAAAAAVAAAAAVAAEAAAEAAGQGSSPKRARVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVV5</accession>
    <name>A0A835WVV5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Copper homeostasis protein cutC homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_001390</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the CutC family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454367.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVV5"/>
    <dbReference type="OrthoDB" id="7392499at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005507">
        <property type="term" value="F:copper ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.380">
        <property type="entry name" value="Copper homeostasis (CutC) domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005627">
        <property type="entry name" value="CutC-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036822">
        <property type="entry name" value="CutC-like_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12598">
        <property type="entry name" value="COPPER HOMEOSTASIS PROTEIN CUTC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12598:SF0">
        <property type="entry name" value="COPPER HOMEOSTASIS PROTEIN CUTC HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03932">
        <property type="entry name" value="CutC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF110395">
        <property type="entry name" value="CutC-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00007768"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00019014"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2454367.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="183" mass="19433" checksum="9D19A702D39D9A1B" modified="2021-09-29" version="1">MVMLEDIRTAKACGADGVVFGALRHDGTVDTVTTGLLWNLANDLSLDATFHRAFDMTPDPIAALDALMLIGVPRVLTSGGAPSALEGADALAELVQRGHGRITVLAGGGVTPGTAGELVRRCRLRELHSTAKRVERSAMLYRRPGMSMVSARAPQDWEWTVADERLVRGLLEAVAEAAAEACE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2024-01-24" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WVX0</accession>
    <name>A0A835WVX0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Pherophorin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_001194</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454158.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WVX0"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR024616">
        <property type="entry name" value="Pherophorin"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12499">
        <property type="entry name" value="DUF3707"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Pherophorin" evidence="2">
        <location>
            <begin position="2"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="637"/>
            <end position="667"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12499"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2454158.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1142" mass="120530" checksum="EA8B6A5EFBC59401" modified="2021-09-29" version="1">MFCFEVQVGACERPKNPCCNADVKKLELDVDVACNKTGFRTFWGKDLSNLKKTPTQPFYDIPDGAPPDGLVLKVTELGLDKSNADGMYICYQYINTGSKTPARCRTPAGLCRRDNSSSADGRVCSVALTSSDNNCCPVTGYTPPTPPSPPSPSSPPPTCTVCVEHNITMVLRPEVAKDAGAVASVSEDICSYLQYGDVFDPLQDQVDPNPACVTAFNAATAKLDVAVKICLRATSALAAQAMTAWYDPNGRLKWLQRLIPSGDTGECKVKDGTAEARISGAPVPTTAPASTAASTAPTAALPLPSASSSTAPASSSTASAPAAPLSWAANASTSISCTTFAPATFTRPALTTATAIALASLPTAPVARAAIAIAPSFPASIARAPFAFATPKTSTPASLSSPTSTTFSFSSSPLTYTTLASTSVPYASIAFAAAASTTLACTAISTSALAHAAVTSAAVSCPTLTRSSFTAATVAIAAIAHTPITTSAFTFTSFSPAFASQSTSFTPRPTFRAASPPPPPTRASAGFQIMIGPFDEFFDEETCLAYNSTTGLLQGSGCDCRDPAQLVKFITVDGSPPYELTSLGPLGPAVIRFVAAEVNRTSGNDTAVPFGCIQQPQPLPNPAVLEDRVTDIVRFGLCPPPQQPRGVGRRLQGRSEGGSSSGNNNEAGAMNAVASAALGAAGPGGGAELGPKRTTYLTFGDPSLGGLTRTGYRRLAQAALTNSPAVVLILRAPDATGRDLCASVLYDTPDQVYPSPLRLSLCNTNLLASAELRLAAIRSEPRNLNRSATSGKFIKQAPEGLVSISYPKYRPTSSDWYQPFTPEKLAEVTDRGPCLFSPAATGQKGEKRAPSDNTTLDVVRSAECSPLTRDLLFRIYKITDVDLPLGNVNSTEINGTITVPEVINQTIKIYQKYVWTHLPQIIPSLTRLNGTRFVPADPTVTLILYGTAFPVLAVEGQELVSGMTRVVLATNFVRANRISEDKPFCDNRYVVAERPDLFNETVQRVYFSNFSTLATPTGRGATNLDNTCDVYIVDYYDNQYSQPLINIMLNRYLSSGNALYAVVPSTLPVDLSTDTAQIRIFDSGIAVDRIVVPPDDLAIGRRRFLQGNSAAVTAAGGQKQELYPRCFSSHWTPFVLHATRTC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WWY6</accession>
    <name>A0A835WWY6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="4">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_002106</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type-I AFP family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453900.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WWY6"/>
    <dbReference type="OrthoDB" id="63514at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016172">
        <property type="term" value="F:antifreeze activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030149">
        <property type="term" value="P:sphingolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000104">
        <property type="entry name" value="Antifreeze_1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393:SF6">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00308">
        <property type="entry name" value="ANTIFREEZEI"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0047">Antifreeze protein</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="653"/>
            <end position="709"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="787"/>
            <end position="833"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="663"/>
            <end position="684"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="804"/>
            <end position="814"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="816"/>
            <end position="833"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006358"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2453900.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="833" mass="87180" checksum="DE1FBE34E00AFDA0" modified="2021-09-29" version="1">MTEEPGDFFSRLPAELHARIATSCLTTNEQACTYRLICKPLAGALSGPEHTTVKMSQPVPPDAFREYWCRPGACAQLSLSKRRQLTQLTASSGVLENLQFALNVSELEPDLGEMCAAAKAGHLHICQWLLENSRDKAVYWRAVSAAASGGHTRVYDWLRSAGGEWNWEALIAAADAGHEDMFWHVLADRPPRPAEPDAYYSHKLMAYKAMEVLRSVARGCSLGLMRRLWREWFVEGVDEIPGLPNGGSGIAEADEVAVVAALGQDVVHMQSLLTEAAGSATSCWMDKVKWIASLGVLGLELGGSTAAAAAAAGAAAPPAGNPANAGAAAAADDFFVAVDAPQPNAEPGFWDCAFKGAAHSRDPVGRLQALKELWQAGRLTYTLPGSGTSSSDGTAAGQPKVRVATWPAAPDGQPKGLLAALEDALSSAVAADNTQAFMHLLDWLVPTSTADSSSSGTAAAAAAATGRGERFLLSALNAALRRDKLHIIQTIHGRAPLSDAAISHLYSNAIVDGALEVMKWLEATFPDADGLGLIRVTSCGRPQEDEGGWYLSRACLSGDIDTVRHLMVVRGLRMSGGHARRAFKYAAQTGVAALIRFLAERGCEMTHKAYISAIFEGDWQTVRLLAELGCPWDNARVVAASNAAAAAGATAADAARKVAGEDGHEEEQEPEEEEDDDEDEDEDTNGNGGWSSDDDFGDDDHWTFFPNRKGKARKPADVYSKVMDDSGVTEEMLQRLVDLGCPRDTAARVETAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAAASKAAGGGGDARSDREEDDEDEDEDTNGNGGWSSGDGGGHANHWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="5" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3S9</accession>
    <name>A0A836B3S9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000024">
        <property type="protein sequence ID" value="KAG2446871.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3S9"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="52"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="100"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2446871.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="110" mass="11665" checksum="DC064D20F6A6408E" modified="2021-09-29" version="1">MANAAPPAGALPHMQFNPELNQQLTQNTFQLMAALNILPLNVGVLGVGQQLAASQPQEELKPQATPRRRAPAKGGRDKKAAADEEAEEAEGLPAIKTPKQRLQGNQAQAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3T5</accession>
    <name>A0A836B3T5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nuclear envelope membrane protein</fullName>
        </recommendedName>
        <alternativeName>
            <fullName evidence="6">Nuclear rim protein</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_008560</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the nurim family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000026">
        <property type="protein sequence ID" value="KAG2446573.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3T5"/>
    <dbReference type="OrthoDB" id="10050858at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031965">
        <property type="term" value="C:nuclear membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1630">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033580">
        <property type="entry name" value="Nurim-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31040">
        <property type="entry name" value="NURIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31040:SF1">
        <property type="entry name" value="NURIM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="4 8" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="12"/>
            <end position="32"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="57"/>
            <end position="79"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="100"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="131"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010631"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00031700"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00032957"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2446573.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="280" mass="30204" checksum="114FCB8373BE6119" modified="2021-09-29" version="1">MLRQIFAMVAWGWAACAMVAMSCWVVDLPALLPHSLSTLLPLSINAPSPIARVGGTAWQAAAWDCCLFLGLAAQHNIMARRRVKQAMRRVAGVPYCLERSVFVLAAGVALAAVVLLWQPLPLTVWQVPAPWSYALTALALAGFGIIYSSASAIESADLLGLQRAFAGAQEEPARHEGPGLVVKSWYQYVRHPIYLGYLLFLFSTPHMSAGRLLYASLNLAFVLWSLPLEEGDIAEELGKPYEAYCHAVPALIPALRPYTVRHGQGGAEGPSGDAQAKKVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3W0</accession>
    <name>A0A836B3W0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008100</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000024">
        <property type="protein sequence ID" value="KAG2446946.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3W0"/>
    <dbReference type="OrthoDB" id="542507at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010903">
        <property type="entry name" value="DUF1517"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR053023">
        <property type="entry name" value="FLAP_modulator"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33975">
        <property type="entry name" value="MYELIN-ASSOCIATED OLIGODENDROCYTE BASIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33975:SF2">
        <property type="entry name" value="MYELIN-ASSOCIATED OLIGODENDROCYTE BASIC PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07466">
        <property type="entry name" value="DUF1517"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="29"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="85"/>
            <end position="129"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="339"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="446"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="92"/>
            <end position="107"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="112"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2446946.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="467" mass="48255" checksum="4011EB6DF73F3297" modified="2021-09-29" version="1">MSLPRLQHGFRPAAASVSKCCPRVVSVASSTTRPPVGPSLEQAPAPQEQPQPRSPTGLAKLRCVALAAVAAAALVLGPADEAQAARTGGRVGGHRSHAAMSLRKRAAASRPGSGLSATSVSSHSGSTASRRYRVPMSLRLRAAPRSGSYTGSIGSARGVAAGAGAGDSSLVTVASAMQQAVHTVQGSVRPPLLIGDILAYPDLAAGIDLEALPLWASLLGLAGANILGLAVVIGILRNIQDESEPVSVVKVQVAMLERRPQLQSKLAELSGMIQVGQQGAWLILEEAILQLLQHQSHIAYGSVAKQQLASKKKAYAAFGEVAEAEAAKAKREESVVRHIGETQSEDEGDQPAPQGGGGLLGGLLSGMGMGGGPAAKEITVVTLVLATRGKLDIPDRVTDWKGLRHALQQVTGLSSDKIMAVELLWTPRSESDYLTIPQLERDYPDLVPLGPANPHPQGAVGSGSPAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4T0</accession>
    <name>A0A836B4T0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="9">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_007526</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the major facilitator superfamily. Folate-biopterin transporter (TC 2.A.71) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4T0"/>
    <dbReference type="OrthoDB" id="547072at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1250.20">
        <property type="entry name" value="MFS general substrate transporter like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039309">
        <property type="entry name" value="BT1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004324">
        <property type="entry name" value="FBT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036259">
        <property type="entry name" value="MFS_trans_sf"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR00788">
        <property type="entry name" value="fbt"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR31585:SF0">
        <property type="entry name" value="FOLATE-BIOPTERIN TRANSPORTER 1, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03092">
        <property type="entry name" value="BT1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF103473">
        <property type="entry name" value="MFS general substrate transporter"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6 8" id="KW-0472">Membrane</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 8" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5 8" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="121"/>
            <end position="142"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="148"/>
            <end position="169"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="190"/>
            <end position="207"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="219"/>
            <end position="237"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="553"/>
            <end position="575"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="581"/>
            <end position="606"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="618"/>
            <end position="638"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="650"/>
            <end position="673"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="685"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="8">
        <location>
            <begin position="727"/>
            <end position="748"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="264"/>
            <end position="425"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="446"/>
            <end position="473"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="754"/>
            <end position="838"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="15"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="319"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="349"/>
            <end position="358"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="364"/>
            <end position="377"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="454"/>
            <end position="467"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="772"/>
            <end position="800"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="7">
        <location>
            <begin position="810"/>
            <end position="828"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2447605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="864" mass="85816" checksum="CC165481279C9949" modified="2021-09-29" version="1">MPSYVPLQTEAEETGAARRQSDHPSQRLPGRIRRYFAIKWRALKSQPNLPELVAIALVYLVQGVTDLATLAQKYLLKDELGASPAQVAFVISAGNVPWTIKPAIGLISDTLPLWGYRRKSYLVAAGLGGAAGWLALAAPAGWGGAGSLGGVLGLIVAVSCASAVSDVVVDSMVVERARREAQADSGSLQSLCWAAYAVGQVGSAWFSGSLVERLGPRPVFALTALLPLLVVLAGLGVRERRGPGVIELLRRLWRGERWGCGVGAAGGEEAGPGAELAPGGGSGGAIEPEELKPLTQRLSGDGGEEGGIDADKGRSPSGGSRGGGGGGRADGGGRWGPGGAGGSSGSGGALAPPAAARAMQRLDGAGGAGGGGGGGGKELLQPGEMWGSSSFAADGHAALSSPGSEGEDDTGLGLDTSDDDGRGAAATATATAAATAAATAAATAAATAAGPAGGRRRKAGRNGRKSRGREAQQQLGVLQPLSCVSIISNGLDATAPAASGGGGSGGSCSRASGRGGGGSSHLLAACGALLGSLRATCVALWGTVRRREVAGPVLFLFLSSATPAADDAMFFFMTAPPPTGLGFSATFLGDVALAVAVASLAGVGVYHVFLRRLPLRRVLLWGSLLAAACQASSLVLATRANVAWGLPDHLFALGDSVLVSVIQNVLFMPTMVLSARLCPPGLEATLFAGLMSIGNVATGLRYLGGWVVGGAALTQALGVTATDFRNLPLLLALCSGALVLPLPLLVLVPPSLDRDRDRDRAEEEEQERGRRGQGQGQGQQPGVGQAGGGAAWGGCGGGGVRTPESSGSEGDLGLGAAGGGGGGGGGAREGLQAQGVGGDAALSAAAMRGGGVSVLQERRHVLVP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4U8</accession>
    <name>A0A836B4U8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="11">PIN domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="12" type="ORF">HYH02_007568</name>
    </gene>
    <organism evidence="12 13">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="12" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="12">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>Mg(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:18420"/>
        </cofactor>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the RNR ribonuclease family.</text>
    </comment>
    <comment type="caution">
        <text evidence="12">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4U8"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019899">
        <property type="term" value="F:enzyme binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010467">
        <property type="term" value="P:gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd09862">
        <property type="entry name" value="PIN_Rrp44-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1010:FF:000021">
        <property type="entry name" value="DIS3-like exonuclease 1 isoform X1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.690">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1010">
        <property type="entry name" value="5'-nuclease"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029060">
        <property type="entry name" value="PIN-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002716">
        <property type="entry name" value="PIN_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033771">
        <property type="entry name" value="Rrp44_CSD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF35">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RRP44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13638">
        <property type="entry name" value="PIN_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17216">
        <property type="entry name" value="Rrp44_CSD1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00670">
        <property type="entry name" value="PINc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF88723">
        <property type="entry name" value="PIN domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="8" id="KW-0269">Exonuclease</keyword>
    <keyword evidence="7" id="KW-0271">Exosome</keyword>
    <keyword evidence="6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="5" id="KW-0540">Nuclease</keyword>
    <keyword evidence="13" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="9" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="PIN" evidence="11">
        <location>
            <begin position="52"/>
            <end position="166"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="201"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="10">
        <location>
            <begin position="311"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="10">
        <location>
            <begin position="319"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="10">
        <location>
            <begin position="330"/>
            <end position="345"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00005785"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022722"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022839"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="11">
        <source>
            <dbReference type="SMART" id="SM00670"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="EMBL" id="KAG2447650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="372" mass="40281" checksum="9E41D912716BC788" modified="2021-09-29" version="1">MHLNNSYIKKTKKGKVVKVVKERYLRDDIWSGSPLDPEADPSSHKLAATAPHYLLIDTNVALHQLDFLEHPAVTDVIVCSTVLEEVQHKNLSAYQRLRAACANPAKRFYVFANEHHRDTHVTANEGESPNDRNDRALRVATRWYRDRIPQDTCPVILLTNDVANRAAAQAEGLAALGVMAYCRQHRADAKELQDLVAAATGDDDDKGGAAGGVAAAEDDDDGGRGGRAAKRKKLYSEHLPYSELQAGIKTNKFYQGTLRVSRFNPFEGWVASEHVGEDILISGRLDMNRALDGDVVAVELLPEAQWRAPNAKLPSAVGGKPGAAGGGEGGGEEGEGGEEEHEEVPEVFQVAPGEHFNDSAGSGKRPTGRVVS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4V3</accession>
    <name>A0A836B4V3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">RNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_007568</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447652.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4V3"/>
    <dbReference type="OrthoDB" id="372421at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000177">
        <property type="term" value="C:cytoplasmic exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000176">
        <property type="term" value="C:nuclear exosome (RNase complex)"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000175">
        <property type="term" value="F:3'-5'-RNA exonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004519">
        <property type="term" value="F:endonuclease activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071031">
        <property type="term" value="P:nuclear mRNA surveillance of mRNA 3'-end processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016075">
        <property type="term" value="P:rRNA catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006364">
        <property type="term" value="P:rRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.700">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.50.140">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041505">
        <property type="entry name" value="Dis3_CSD2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012340">
        <property type="entry name" value="NA-bd_OB-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001900">
        <property type="entry name" value="RNase_II/R"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR022966">
        <property type="entry name" value="RNase_II/R_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050180">
        <property type="entry name" value="RNR_Ribonuclease"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR033770">
        <property type="entry name" value="RRP44_S1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355:SF35">
        <property type="entry name" value="EXOSOME COMPLEX EXONUCLEASE RRP44"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23355">
        <property type="entry name" value="RIBONUCLEASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17849">
        <property type="entry name" value="OB_Dis3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00773">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17215">
        <property type="entry name" value="Rrp44_S1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00955">
        <property type="entry name" value="RNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50249">
        <property type="entry name" value="Nucleic acid-binding proteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01175">
        <property type="entry name" value="RIBONUCLEASE_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0271">Exosome</keyword>
    <keyword evidence="4" id="KW-0539">Nucleus</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0698">rRNA processing</keyword>
    <feature type="domain" description="RNB" evidence="5">
        <location>
            <begin position="88"/>
            <end position="420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022552"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022835"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="SMART" id="SM00955"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2447652.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="588" mass="64278" checksum="1AC66E4FEDE3EDE4" modified="2021-09-29" version="1">MIRIQTRQAEGLMDKRIVVVIDGWDADSAYPRGHYTRTLGVIGERETETEVILIENDINTNPFTPAVHDCVPPLPWAVGPAELADPNRTDLRHLCVASVDPPGCKDIDDALHVRRLPNGNYELGVHIADVTHFVKAGSAMDLEAASRGTTVYLVERRIDMLPKPLTEDICSLRCDVERLAFSVLWEVDEQANILNTHFTKSVIKSRASLTYQEAQSRIDDQSMTDELTVSLRTMNKLAKIMRARRAAAGALQLASPEVKFKIDTETHNPLDVGMYQIRDTNQMVEEMMLLANVAVAEKTLRHFASCALLRRHQTPSERQFEPILKAAAAAGFALDVATSKALAASLDGAVRADDPYFNKLVRIMTTRCMTQAQYFGSGDCAPSEYHHYGLAAPLYTHFTSPIRRYADVVVHRLLGAAIGLEPLPDSARDKEALHNCSDNLNKRHRNAQMAGRGSVELHTLIFFKDRTTVADARVTKVKANGLVVFVPKYGIEGPVFLAPKDKNNAAAPATGSGSGSGAAGSGAGASSSKQFLLDEEAQTVTAADGSVRYAVFDKCAVRIGVEEGVAHRRSLVLTLVDRAELPDSERVG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4V8</accession>
    <name>A0A836B4V8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="8">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_007583</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
            <topology evidence="1">Single-pass type II membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the glycosyltransferase 31 family. Beta3-Gal-T subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447667.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4V8"/>
    <dbReference type="OrthoDB" id="421979at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026050">
        <property type="entry name" value="C1GALT1/C1GALT1_chp1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033">
        <property type="entry name" value="BETA1,3-GALACTOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23033:SF50">
        <property type="entry name" value="HEXOSYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="6" id="KW-0472">Membrane</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0735">Signal-anchor</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="5" id="KW-1133">Transmembrane helix</keyword>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="105"/>
            <end position="148"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="181"/>
            <end position="403"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="112"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="131"/>
            <end position="140"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="181"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="200"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="7">
        <location>
            <begin position="216"/>
            <end position="235"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="7">
        <location>
            <begin position="243"/>
            <end position="291"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="335"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="7">
        <location>
            <begin position="350"/>
            <end position="384"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004606"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006462"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022968"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2447667.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="645" mass="72003" checksum="261BB46C1246A9A9" modified="2021-09-29" version="1">MLYGDDDTLFYMSGVIKLLEQFDPEQPLAITDNIWYFSQHPAPAAPRCLPCGFNLSTITTNHTFTPRPACPFCTRALACGTYSPRYRCNATHEAALRQRFGPRLLTWPLGPQEGRQQQQQQQQAEGKEGEEQGGDGDADSEEARGRFGEGMREAGAAYARWMAHHVELKERYPRDFRYKPAMDWEQRDPPARGSGGGGGEEPEGSEDTDPQTWYGGRRRRLRRRGQRRRRQRRRGLLQGQGSEEWEEWDGEEAVDGNNEEEEEEEEEEEEEEEEEEEEEEAAAVVVEEADEAAWWQQRRAKRRRGQLAWQQAAGGSAGPGRGTAEDERTTSTRWQRSQQVKQQAQQLEQQAEHLEEPQRGEPQRGEPQRGEPQRGEPQQRGEQRRRLRAAGGSSKRPSQQRFVDGTAWLSAALGLDLSRAAQGDQAAAEAREALRLPFPYCARHDERLHAKPAQSCLVSISGHGGTGVIFSVGLLRLIAPEDAIAFITKQTGCGGGDCLLGRALWFRMGIGYTDPGTPLQHGAARYERYARFIDSNTQMPSLITLADPPKVLLNARRGTARAPACDRSCVWLIEHVVGTHVRAQGKKVDDTVAAMHTHLEAHATAYAWIQEARADPAVAAGNVSVPHWIRERYGPPPGVKAGGNG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4W3</accession>
    <name>A0A836B4W3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">BHLH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_007415</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000021">
        <property type="protein sequence ID" value="KAG2447488.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4W3"/>
    <dbReference type="OrthoDB" id="690068at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003700">
        <property type="term" value="F:DNA-binding transcription factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046983">
        <property type="term" value="F:protein dimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006351">
        <property type="term" value="P:DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd11453">
        <property type="entry name" value="bHLH_AtBIM_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="4.10.280.10">
        <property type="entry name" value="Helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011598">
        <property type="entry name" value="bHLH_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044295">
        <property type="entry name" value="BIM1/2/3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036638">
        <property type="entry name" value="HLH_DNA-bd_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46412">
        <property type="entry name" value="BES1-INTERACTING MYC-LIKE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46412:SF3">
        <property type="entry name" value="TRANSCRIPTION FACTOR BIM1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00010">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00353">
        <property type="entry name" value="HLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47459">
        <property type="entry name" value="HLH, helix-loop-helix DNA-binding domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50888">
        <property type="entry name" value="BHLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="BHLH" evidence="2">
        <location>
            <begin position="137"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="114"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="202"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="376"/>
            <end position="411"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="462"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="132"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="224"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="242"/>
            <end position="252"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="376"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="450"/>
            <end position="459"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50888"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2447488.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="560" mass="55526" checksum="770E6B63AFA76C5E" modified="2021-09-29" version="1">MQPTSLTGRQQQQLGLLSLAGRAQPDMLEAARVAALLNGQGGSFNLPTTGLGSGALSGQSLNLSLGSLPTSSLPQASQQAPLQQSSQLGLPDQLALLSGFPAALFPQQYGSGDRDLQLGGMRNAGKTKSSDSRSSSAYASRHQAAEQRRRTRINERLELLRKLVPHAERANTACFLEEVIKYIEALKARTLELESQLETLTGKPVPKSLPLPTGMPSVLGGGSNSADNTTASPRTLAVVGAATSSQGGPASSQPLGGQQGAGNGAGSLASPSNTPPPTMTAQQASQQLALIQAGGSGGLPAQLTLPSAGGGGVGAGLLSAAQQSLLGFPQSGGLSLAGAGLSLGGSGLGGHGTGSISLTQFAGNLQAAAAAAAAASHGAGSHSHGSHSQQHSGLSGLGTSSHHHHHVTASQQLSELQAVQMMQSLQQHHSAAAAAAAAASAGAGSGAGAGSSRPGAGSSTFHPTNNKAFLHFNEDAYGGAFGGGAGGKAVELSLPARSLLGAAAASAATPSTSLQLTTVQLPTDSNTLLQVETARKALSGSPVSSEESGVPLKKRKVLVL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B4Y7</accession>
    <name>A0A836B4Y7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Golgi SNAP receptor complex member 1</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_007201</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="9">Involved in transport from the ER to the Golgi apparatus as well as in intra-Golgi transport. It belongs to a super-family of proteins called t-SNAREs or soluble NSF (N-ethylmaleimide-sensitive factor) attachment protein receptor.</text>
    </comment>
    <comment type="subunit">
        <text evidence="9">Component of several multiprotein Golgi SNARE complexes.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Golgi apparatus membrane</location>
            <topology evidence="1">Single-pass type IV membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 9">Belongs to the GOSR1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000020">
        <property type="protein sequence ID" value="KAG2447742.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B4Y7"/>
    <dbReference type="OrthoDB" id="422156at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005801">
        <property type="term" value="C:cis-Golgi network"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005797">
        <property type="term" value="C:Golgi medial cisterna"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000139">
        <property type="term" value="C:Golgi membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031201">
        <property type="term" value="C:SNARE complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005484">
        <property type="term" value="F:SNAP receptor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006888">
        <property type="term" value="P:endoplasmic reticulum to Golgi vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048219">
        <property type="term" value="P:inter-Golgi cisterna vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0015031">
        <property type="term" value="P:protein transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006906">
        <property type="term" value="P:vesicle fusion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023601">
        <property type="entry name" value="Golgi_SNAP_su1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094:SF2">
        <property type="entry name" value="GOLGI SNAP RECEPTOR COMPLEX MEMBER 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR21094">
        <property type="entry name" value="GOS-28 SNARE- RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12352">
        <property type="entry name" value="V-SNARE_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PIRSF" id="PIRSF027109">
        <property type="entry name" value="Golgi_SNARE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0931">ER-Golgi transport</keyword>
    <keyword evidence="7 9" id="KW-0333">Golgi apparatus</keyword>
    <keyword evidence="8 9 10" id="KW-0472">Membrane</keyword>
    <keyword evidence="5 9" id="KW-0653">Protein transport</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 10" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 10" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 9" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="10">
        <location>
            <begin position="219"/>
            <end position="238"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004409"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008473"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023034"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="PIRNR" id="PIRNR027109"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2447742.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="239" mass="26006" checksum="946E1941E71C889A" modified="2021-09-29" version="1">MAYRPAPARPPGQTRVWEDLRKEARRLEGELDVKLAAFTKLCSSFEASYKLNTADNSLGADQLAQTKAAEVEDLLQRLSDINDEMAAIVGGSTDSRSHTLARHRDILQEFTQEFRKVNATLGAALDRVKLLAGASDSPHLSVNVQNTSGALLRERGTIQNSANMVDDILSQAANVSGNLLGQRRVFEGAMDKLVQVGSRFPVVNGLLNAIRRKKSKDTLVLAGVIAACVLFTILYVMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B576</accession>
    <name>A0A836B576_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_006981</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="2">Cytoplasm</location>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000019">
        <property type="protein sequence ID" value="KAG2447952.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B576"/>
    <dbReference type="OrthoDB" id="543373at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:001849">
        <property type="entry name" value="Importin beta"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058584">
        <property type="entry name" value="IMB1_TNPO1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041653">
        <property type="entry name" value="Importin_rep_4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR034085">
        <property type="entry name" value="TOG"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057672">
        <property type="entry name" value="TPR_IPO4/5"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13513">
        <property type="entry name" value="HEAT_EZ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18808">
        <property type="entry name" value="Importin_rep_4"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25574">
        <property type="entry name" value="TPR_IMB1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25780">
        <property type="entry name" value="TPR_IPO5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01349">
        <property type="entry name" value="TOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-0653">Protein transport</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5" id="KW-0677">Repeat</keyword>
    <keyword evidence="3" id="KW-0813">Transport</keyword>
    <feature type="domain" description="TOG" evidence="8">
        <location>
            <begin position="362"/>
            <end position="608"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="SMART" id="SM01349"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2447952.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="852" mass="91407" checksum="53B2E4664ADA450D" modified="2021-09-29" version="1">MDPAAAAAAVAAIAANPPAFTELVAQLQDADNDRRKSAEAIFDALKEQSDLCMTCLARTLRTCPAVEARLFCSVMIRKVIYYRSDTDLKAPVLWDKCSPAVQTGTKQALLEALVQEPDRNVSSKVSSAVSDLAALIYDKAGWPELMPAITGMLTSSNQQQVVNALSVLADVAAYLAEHLKPQLQDFVNMLVTMLNSGVKDVTVGAANAATAFIEAYEDTRAREVLSPLVQPMLAVLGQLLSSGDEEEARGVLEMFIVLAESSARFLRPHLIPLVDAMMRVAGAGDTLEPQSRQLAVEFLVSLCEAREQSPGMMRKVPNLARTLFELVMGFLLDIEDDPGWHSAADDTNEDAGAGELYDPGQEYLDRLALSLGGKAVSDAAAPLLGTWISDAQWQKRAAVFICLAQIAEGCTKIMSAPAYLEQLARMCVMGLKDAQPHVRWAACQALGQMCTDLGPELQARHHAAILPALMEVMDNFNAPRVQAHACAAIVNFSEGVEADVLPPYLDGLIQKLLTLLQHGARLVQEGALTALASVADSSQDLFLKYYDTVMPLLLHILTSANAKEHRLMRAKALECISLVGMAVGRDRFRDHARQVLAYMQQVQAAGVDPDDPLASYMLQAGARLCKCLGPEFIEYLPLVMPSLLASAQADPDVQVVDEDEVNAEDLPDDMEAIAMGDKCLMYRSSILEEKATAVNMLSCYAEELKEGFWGYVGPVLKLVLNGVEGQSPLIKFYLNEEIRRSAAALLPSLLKCCINAAERGVPGASPAAVGEFLGAAWGPLLEALRKEPEGEIQAVQLDSIGEIVEMVPDKGLLGAEPTAAAFKIFDTVLEKVRGGGGGAGEGGAGRGGEGCL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="19" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B588</accession>
    <name>A0A836B588_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">TOG domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_006981</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000019">
        <property type="protein sequence ID" value="KAG2447950.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B588"/>
    <dbReference type="OrthoDB" id="543373at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006606">
        <property type="term" value="P:protein import into nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR040122">
        <property type="entry name" value="Importin_beta"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041389">
        <property type="entry name" value="Importin_rep_6"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10527">
        <property type="entry name" value="IMPORTIN BETA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF18829">
        <property type="entry name" value="Importin_rep_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="5" id="KW-0653">Protein transport</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="1"/>
            <end position="16"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022927"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2447950.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="302" mass="32275" checksum="CE627085B77C94AA" modified="2021-09-29" version="1">MAEKRRADRAGRRSTEDFDAEEAEQLEAENELEEELFDQVAACVGAFLKKMGDDVLPLVESLLMARYGAMLTDKSRSAEERRIAICLVDDLLENSPAGMVKHFANVLPILLEATRSEHADLRQCAVYGLGVMAAKAPAELFRPQAAAVAEIMAGIVRHPEAKSEDNDMATDNAVAALGRVLKHHPEALGPDGGAAYAQLWLGSLPLKADAVEATAMHEQLVAMCEAQDPRVVPHVAKVAVVFAEVLGGGKTYVAGPVGVRMAQLLHRLQGAVPAETVQGVVAAFTPKQQASYAAYMAGNIPE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B793</accession>
    <name>A0A836B793_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005530</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449379.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B793"/>
    <dbReference type="OrthoDB" id="541154at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052396">
        <property type="entry name" value="Meiotic_Drive_Suppr_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR37171:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE YRZF-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="360"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="650"/>
            <end position="759"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="366"/>
            <end position="378"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="662"/>
            <end position="678"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="706"/>
            <end position="728"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="745"/>
            <end position="755"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449379.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="784" mass="82193" checksum="5C0934EBDA0C87A6" modified="2021-09-29" version="1">MEQTDTKFISGLANEFNLDTAWELRAVTAFTKAGSAIRAHIRGHLHKNKQVDLLNGLMQAGLGVGSAAGAEAVPETLLQSTVYRFTSAGDFLSNYQPHRLELLPCASAQTMGVKCKGPSAVVPWHTFEDECRALLHVLPDGGQANLVVPTPTPTSAAVGNEDNLHLELFTHILRPLQQALSSTDGFFEAARATQGVTKGIWTNKSARADFVLQSCINSELLVAIEVKTSAVICVPQSSSLPAMYAAADKDSNIVECVAQLFSYLGVVPFGVLVTDQQLFCMRREGTVLLCSPSIPLAGYVHCPAERGPGRPSKAELLAATKAAETARRQFEAGGGRSADSLTAVAALYCMAKMSQQWWLQQPPQPTGGGGQGNSGGDSGADSTGANNPWSSFLQCLLAWVGIRSLEGAQHPAAAAAPRPVPDLPTDAECECTSSQLFPGRCFDPRVPGGMPPPLGNACLGVVLEGAVGGRAAAVKLVDLWQGPEGKEAVLREVRTYQLLQPLQGVNVPRLLGYGFCDEWQYFLATSLEGPTLASEEGWALGDEATCAAAFAALDAVHRCGVLHGDIALRNFVLAAVQPAGVGGGSAAGGSVYGGGGSETSITGQQPQLQPRVMLLDFGHAQLVAEAAEEWGEEPASLMQRERRALQDLLGWEPSPPLPVSRPPVDTDAGSSAKAAAASGGAGGDTGGQAQHPQPGMQEMDADMALPGGSAAASRPSPPASQRSAGPRSAFPPAPPTRLPSRPSGWHQQLQFSRPQMSHVPHPLAWNGLNGGRSASRLSWRKIAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BAM4</accession>
    <name>A0A836BAM4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_002158</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Protein modification; protein ubiquitination.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452811.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BAM4"/>
    <dbReference type="OrthoDB" id="541282at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1280.50">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036047">
        <property type="entry name" value="F-box-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001810">
        <property type="entry name" value="F-box_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052121">
        <property type="entry name" value="F-box_SCF_Substrate_Recog"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46550">
        <property type="entry name" value="F-BOX ONLY PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46550:SF1">
        <property type="entry name" value="F-BOX PROTEIN 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12937">
        <property type="entry name" value="F-box-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81383">
        <property type="entry name" value="F-box domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50181">
        <property type="entry name" value="FBOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0833">Ubl conjugation pathway</keyword>
    <feature type="domain" description="F-box" evidence="4">
        <location>
            <begin position="78"/>
            <end position="124"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="156"/>
            <end position="188"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="288"/>
            <end position="314"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="3">
        <location>
            <begin position="15"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="57"/>
            <end position="73"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="170"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="288"/>
            <end position="304"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004906"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022786"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50181"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2452811.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="433" mass="44436" checksum="33D44D4E59027961" modified="2021-09-29" version="1">MDHVGDELEQAFTDWDAEQDAGQDDLEANKHNNHDSDGNARSSAREGADSPAAPMPHASGGHASSRGAAGASSTPRPHLNLLQLPREVLLRVMSLLPATGLTAAACACKLLSELASEDTVWRRLYLCRWGKPEQHVRANGKQWKRTYLDADGEEWEATRRQHQDLDLVPLPTPAPTPSPAGPSAAGGAAAGASARAVGRCRGGGAAAAAASTIGRPVPSGASGSSSAAAAAAAPGAGGAPSVGLGAMFLDMLRAKRDTAPDRRLLDAQLGADPGDIAAKVAAWRRARGFANPGPGAGPSGSSAPQLPPRPDLSHRGRAALTFTRVNPGEEPPVYACEQTGWVHVCGDACTEGVVDARSELLVCPVSGQTTDRLVHECEEDEADGGRCGGGAGGGGEEDGLGLGITAGFGRYFTAGYECDNAQQLNKLLGYKAL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BB24</accession>
    <name>A0A836BB24_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_002781</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452544.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BB24"/>
    <dbReference type="OrthoDB" id="1717591at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0031982">
        <property type="term" value="C:vesicle"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030276">
        <property type="term" value="F:clathrin binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072318">
        <property type="term" value="P:clathrin coat disassembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0072583">
        <property type="term" value="P:clathrin-dependent endocytosis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172">
        <property type="entry name" value="AUXILIN/CYCLIN G-ASSOCIATED KINASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23172:SF19">
        <property type="entry name" value="J DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="33"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="442"/>
            <end position="536"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="582"/>
            <end position="670"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="754"/>
            <end position="791"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="43"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="83"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="96"/>
            <end position="111"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="179"/>
            <end position="192"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="217"/>
            <end position="233"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="234"/>
            <end position="243"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="245"/>
            <end position="254"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="299"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="505"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="605"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="617"/>
            <end position="627"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="628"/>
            <end position="637"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="647"/>
            <end position="670"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2452544.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="871" mass="87602" checksum="EED4A4C413328CE4" modified="2021-09-29" version="1">MAASRKNDPFNFDDIYKQAGVEDLFVKKTLGELKHKTSPGPTPVAAARAPATASTSHAAAPAAASFDLDFLSSIATPGGGGTPTNLSKPGSSANLQQQAQPAVAPKPAQHAASDDPFALFNEVPGAAPALRHAPPPPPAAAASSGLGNLLDFDDGHAFAPAPVSTPAPAPVTHTLAPAPAQPPAPAPTPAPAAPVAAPHSPPPPAYDDHSAYSPVTGASYSSASAAAAPAASAGGDGSYGRGHPGSSQSYSQPAPQHFQEPPPEARFHSTTASPGVGPSPPSFGHQHSGRSGQFEDAHSQASASGSSMSAPYAWGHASHGSASSGAGGISGYLKAFTKKAVRVAKAGLAQLEHALEGLDQGGAGAGGGGAGGGGGGQYAGSGYSTSADRGGDGGQISNDEALAWAVRLADMAPHAQQQELAQMPPPLRRRVIEVLREQIRSEHEAARSGSHVSAASSHETHDTYVPPGAGHGAPMSPPPPYRGSSDGSAYQAPHIGAPAVAAAPAAPPPAPVAPPPPPAAAHHESHDLLGMGSGGLSPMGSAVPAAAAPTTHATYPSVPAATAPSVLQPAAHTSAPAPAPVVEDLLGFGSDGPSPAAAPRPAEPAAPAAAPAAAPAQPHPPAPPPQQPAAHVPAAAVHVDDMDDFFSGGRPAAAAAAPQPPAAAAARAGSVHASASAPHLAATGRSGGVSGSGSAAALFDMLHDEDAGAGVDVGNVDVSDYADLYKGEQGHENEPEIRKRLRAQREKAKHDQMKAALKAKLELEAEEAARREQQVELKEQYKANIEAWKNRNKGNIRGLLGSLQTVLWPDSGWTPVSVGDMLEPVQVKKVWMKANLLVHPDKVRQRNGTAEQVAIADMVFDVLKDTYNSFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BB31</accession>
    <name>A0A836BB31_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Nucleolar complex protein 2</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_002526</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the NOC2 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453202.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BB31"/>
    <dbReference type="OrthoDB" id="10266662at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030690">
        <property type="term" value="C:Noc1p-Noc2p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030691">
        <property type="term" value="C:Noc2p-Noc3p complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005730">
        <property type="term" value="C:nucleolus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042273">
        <property type="term" value="P:ribosomal large subunit biogenesis"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005343">
        <property type="entry name" value="Noc2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687">
        <property type="entry name" value="NUCLEOLAR COMPLEX 2 AND RAD4-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12687:SF4">
        <property type="entry name" value="NUCLEOLAR COMPLEX PROTEIN 2 HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03715">
        <property type="entry name" value="Noc2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3" id="KW-0539">Nucleus</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="168"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="194"/>
            <end position="275"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="293"/>
            <end position="323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="4">
        <location>
            <begin position="33"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
        <location>
            <begin position="58"/>
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        </location>
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        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
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            <begin position="206"/>
            <end position="230"/>
        </location>
    </feature>
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    <feature type="compositionally biased region" description="Acidic residues" evidence="4">
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            <begin position="252"/>
            <end position="267"/>
        </location>
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        <location>
            <begin position="302"/>
            <end position="311"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="314"/>
            <end position="323"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005907"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2453202.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="748" mass="80462" checksum="BEC51BE0E16455EC" modified="2021-09-29" version="1">MAKKGHLKNAIHTRRKHKRISGRRGPPGAKGGRRTEVVKAGDEFRKEKAEAKKKGAFDDMDAEEFLQGGFEDDFEDEDGDVEGGSGSEDDDLDDIDDLEEAGDDDLDDDDDDDELDGDDDDEDGDGEEDGAVEGLSGEEEEEEEEGDEEAEEAAAAAAGDAVAADNKRLRGEISKHRAQLEALREKDPEFYKYLQEADAELLGFGDGEEDDEDDEEESDDEEDEDEEDEEAGAKKKAKKEAAKKAKKGAEPGSEEEEQEGGSEEGADDQPGTSGRIDVTSALVAKWCAAALGKAPEQEQGKKAKQQQKKNKGGAEAGNGGGAAAPGAPALGSFSYLVKAYRLACHYGDPSEDAEEGRLRITSSTVYNTIMLFMLREADGIFRRLLGLPPHGAAPSSSSSKKQADVAKNPRWRKVGPLVKSFWGNSIHLLSSVTDPALLAFTLRRLRASVGLLAPFARLRDRFLRACLGVFGGGEVAPRLQAFLALRAAAVELPAPALDNVLKGVYRTYVSNAKFVSSASAPHIAFMSTCIVELWGLDMAASYQHAFTAVRQLAALMRTALSSKSADSYKAVYCWQTVNCMELWAKVLGAHHDRPELKPLVYPVVQLLLGAARLVPTPRYFPLRLRLARALNRLAAQSGVFIPVGPLVVEALGWADLRRPPGGGGGKGGGKGAAALGADGCPDLSLQLKLGKALLRSSAVQEEVVTQLLEVLAEHLACWSCSIALPELAHVPLLALRRFAKACPVERFR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BB32</accession>
    <name>A0A836BB32_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SH2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_002865</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452630.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BB32"/>
    <dbReference type="OrthoDB" id="541552at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00173">
        <property type="entry name" value="SH2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.505.10">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036860">
        <property type="entry name" value="SH2_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55550">
        <property type="entry name" value="SH2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="189"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="490"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="490"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="500"/>
            <end position="510"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452630.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="904" mass="96387" checksum="92423808CF241F5F" modified="2021-09-29" version="1">MGGSTPPWFSSDYPDLAAKREPFPGVDRYQTSYVRYGQAEEALQGAWETETCRRTMAENGQDLNAFYPPGSLPETISLRIIEAPAEFALPVKQDRRLFPCFKVRVEAKHRGPFSLPLTLRAHVLTQQDKEHIGTWVPPEEDPNIDDKSQQRCGTELKGLSVIRHTWEPNARPHVFAQEMKKFQHQLAMPPPAPSGGATVKAEPSNSSFNGAMGPGNGRNMAHLFGGDRPDPVVTLASSAPLGGAGTGRDSLEAVMESLINAGPLSNPGNGGGVDSVASESNSGKLVNHMRTLQAQQQAALAAEQQAAAQAAALQATLQAQRAAAQAEAGGVDRRASVAQGNGAAAASAESRGFISFQDYEFTNLEFLKPTRMNKVFMVFTINIAGLDDLIYVAFNVPTIGICRAEQREKACKKLNIDFKLLSHFDHTGSNHANNNNNHNSNMNSDVSKSLALRANGPLGSALGGLPGVAPQSAMPSSVAAGGGGLSVSRLNGGSHSAGSAGDGSGCGSGSASGEVKATGGMGLHEVGMAQYATSQLQAGPGQQQMMQQMNALKQQQQQQAYGAAQQDVAFQLQQQQAQAQLQQQRMALAAAQQQQQQGLGNGMVPGAPGSGGGAGNGLGPTAEFYLAANGGSLPPPQGSAVGMGIDNGMGAMASRKRDQGPKEEENCRFQPVQQSDLPPYTAFAGLTSSDVDMLLPAPHSRMAMRDFINDVYESTGLHRKLTHMDMQALLSQAGFPSESMREHDTISQQQWDEFCAQFRNIVGTLQQVASVWNMEDPVVISGFDMDRAGTINALVNEPAGTFICRFSMSQPGCLVLTCKVGPTHPRADAMGLVHAIIKIDDLHERRVDTWIRDYAGATHLLDVYRCKRVDKRKVFATNYTRLRGLEVGDVPPPAPFAMTPGGFM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BC07</accession>
    <name>A0A836BC07_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_001027</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2453981.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BC07"/>
    <dbReference type="OrthoDB" id="540439at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="223"/>
            <end position="256"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="327"/>
            <end position="371"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="223"/>
            <end position="247"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="342"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="353"/>
            <end position="365"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2453981.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="680" mass="64439" checksum="3363EA73110045E9" modified="2021-09-29" version="1">MWPFVQPFTNGHGGPACPCRPQEQQGTKPVFFDRHATFRRLRDESLSRVVEEEPAAPAAAAAAAAAGSSAARCPYLPDWSVARSGVWALAEAGLIRAMEAAEREDVSAAAAAGSSSSSSSPAAQSPASASAPLAATAAPVAPAVPHPDAATTIEHLTQLLPRPARISTMAQEPAAASAAAPAMAAAAAAAAAVPEAAGSPATGRSQHATPFATHHVNLEPLSPAASAAAPSSQGAAPAAGAAAAPAGRQPSVPTSQSFTIGRSAAAGADGAGAASPGADGVGSSLRSWLSRVRSAGHGAAGVPVPLGLGSSATLTPLQSLRGSLRRHLHGNPHISEGGGAAASGSPSAASASGGTGHAGSAGGGAPPRRGHAHHVAFAAGLAAATSTAVAVSSVGGGAVSGFVGAATAATSAAAASVAALSTASAAVQLGGHAIAAGSDMLLNRVQGKAVKKASALVADAVLGPAASAGLRHVLLQRLRATVAGASVAWFLMNHMALSDGLVHLDFEHDFVHSAKLMLDLATSGPQVLENCRELMQIGVALTMGVANSSRGGAGAASSGGGGGAAAAAAAGSTGTAAAAAAAAAAAHAAADASHTANSSLAEAVAAEAATAIAAGEMVGGELAVAAAAVAVAAGGAAASAAGGLLAEAGSAGGGAALQEALQGALNNIESLRDGSFGRAR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BC44</accession>
    <name>A0A836BC44_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Methyltransferase type 11 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_001154</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="4">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454117.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BC44"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008757">
        <property type="term" value="F:S-adenosylmethionine-dependent methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013216">
        <property type="entry name" value="Methyltransf_11"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591:SF81">
        <property type="entry name" value="MAGNESIUM PROTOPORPHYRIN IX METHYLTRANSFERASE, CHLOROPLASTIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43591">
        <property type="entry name" value="METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08241">
        <property type="entry name" value="Methyltransf_11"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="1 4" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 4" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="2 4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Methyltransferase type 11" evidence="5">
        <location>
            <begin position="16"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif II" evidence="4">
        <location>
            <begin position="47"/>
            <end position="55"/>
        </location>
    </feature>
    <feature type="region of interest" description="SAM motif III" evidence="4">
        <location>
            <begin position="74"/>
            <end position="83"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF08241"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2454117.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="202" mass="22044" checksum="A7E22BB91B3C2D57" modified="2021-09-29" version="1">MDGYPPPLAAGCYAQAARANALSKEQGFGDRLQFQVGDALAQPFENGSFDLVWSMESGEHMPDKKKFVSELARVCAPGGTVIVVTWCHRVLGAGEAGLREDEKALLDRINEAYYLPDWCSVADYQRLFEAQGLTDIQTRDWSEEVSPFWGAVIATALTSEGLAGLAKAGWTTIKGALVMPLMAEGFRRGLIKFNLISGRKPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BC55</accession>
    <name>A0A836BC55_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">peptidylprolyl isomerase</fullName>
            <ecNumber evidence="1">5.2.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_002112</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="1">
            <text>[protein]-peptidylproline (omega=180) = [protein]-peptidylproline (omega=0)</text>
            <dbReference type="Rhea" id="RHEA:16237"/>
            <dbReference type="Rhea" id="RHEA-COMP:10747"/>
            <dbReference type="Rhea" id="RHEA-COMP:10748"/>
            <dbReference type="ChEBI" id="CHEBI:83833"/>
            <dbReference type="ChEBI" id="CHEBI:83834"/>
            <dbReference type="EC" id="5.2.1.8"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="5.2.1.8" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453908.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BC55"/>
    <dbReference type="OrthoDB" id="1902587at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009507">
        <property type="term" value="C:chloroplast"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003755">
        <property type="term" value="F:peptidyl-prolyl cis-trans isomerase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.10.50.40:FF:000047">
        <property type="entry name" value="Peptidylprolyl isomerase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.50.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044183">
        <property type="entry name" value="PNSL4/FKBP13-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046357">
        <property type="entry name" value="PPIase_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001179">
        <property type="entry name" value="PPIase_FKBP_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47833:SF2">
        <property type="entry name" value="PEPTIDYLPROLYL ISOMERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR47833">
        <property type="entry name" value="PHOTOSYNTHETIC NDH SUBUNIT OF LUMENAL LOCATION 4, CHLOROPLASTIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00254">
        <property type="entry name" value="FKBP_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54534">
        <property type="entry name" value="FKBP-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50059">
        <property type="entry name" value="FKBP_PPIASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0413">Isomerase</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0697">Rotamase</keyword>
    <feature type="domain" description="PPIase FKBP-type" evidence="2">
        <location>
            <begin position="59"/>
            <end position="153"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00277"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50059"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2453908.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="153" mass="16238" checksum="1960FDFA05C8FAB7" modified="2021-09-29" version="1">MALLQTRSVVARCSTAARRAAPARLLSVRTYAADGLTTSKSGLQWKDVEEGTGPAPAKGSTIRCHYNGRLTNGTVFDSSYQRGRPLSFQIGVGQVIKGWDMGILGAEDIPPMKEGGKRLLVIPPELGYGARGAGGVIPPNATLEFDVELLGRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCQ3</accession>
    <name>A0A836BCQ3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">APAF-1 helical domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="6" type="ORF">HYH02_001038</name>
    </gene>
    <organism evidence="6 7">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="6" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="6">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="6">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2453995.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="526819at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00200">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.370">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR041452">
        <property type="entry name" value="APAF1_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011047">
        <property type="entry name" value="Quinoprotein_ADH-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020472">
        <property type="entry name" value="WD40_PAC1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019775">
        <property type="entry name" value="WD40_repeat_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848:SF8">
        <property type="entry name" value="F-BOX AND WD REPEAT DOMAIN CONTAINING 7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19848">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF17908">
        <property type="entry name" value="APAF1_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="23"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00320">
        <property type="entry name" value="GPROTEINBRPT"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="25"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50998">
        <property type="entry name" value="Quinoprotein alcohol dehydrogenase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="4"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00678">
        <property type="entry name" value="WD_REPEATS_1"/>
        <property type="match status" value="5"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="22"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50294">
        <property type="entry name" value="WD_REPEATS_REGION"/>
        <property type="match status" value="16"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="7" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="domain" description="APAF-1 helical" evidence="5">
        <location>
            <begin position="1279"/>
            <end position="1392"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1451"/>
            <end position="1473"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1502"/>
            <end position="1525"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1530"/>
            <end position="1561"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1731"/>
            <end position="1747"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1774"/>
            <end position="1815"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1816"/>
            <end position="1857"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1858"/>
            <end position="1889"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="1947"/>
            <end position="1971"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2033"/>
            <end position="2064"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2085"/>
            <end position="2120"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2134"/>
            <end position="2175"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2176"/>
            <end position="2217"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2218"/>
            <end position="2259"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2260"/>
            <end position="2301"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2327"/>
            <end position="2350"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2351"/>
            <end position="2393"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2394"/>
            <end position="2427"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2451"/>
            <end position="2490"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2504"/>
            <end position="2537"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2600"/>
            <end position="2633"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2652"/>
            <end position="2693"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="2694"/>
            <end position="2725"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="106"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="997"/>
            <end position="1104"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1427"/>
            <end position="1448"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="1990"/>
            <end position="2009"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2548"/>
            <end position="2579"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="2854"/>
            <end position="2873"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="43"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="115"/>
            <end position="130"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="135"/>
            <end position="161"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="1055"/>
            <end position="1078"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="2548"/>
            <end position="2560"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="2862"/>
            <end position="2871"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="5">
        <source>
            <dbReference type="Pfam" id="PF17908"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="EMBL" id="KAG2453995.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="3187" mass="328320" checksum="8F798747339E686B" modified="2021-09-29" version="1">MGCGASVDRQGPAPEPRPRAAPATPPEADKGLAGRPAGAASGKLGGGSGGAAVAGKPPAGGGGVAGSVAAPPPGFPGHNLEANFTDEQLRLWNVTKMLGRLAAVAADDDGGGGSVPSSPAAGSGARAASRLARKGAGGSNGGGSGDGDAFGSGGGVGGQSGGVSAAESAENVRKQVSECAVSLEFLLEFAREIPDDWRTGQVVQQLVKGFTAPQQSRFTDLMPSRHVKRPDYFISHKWDSPFHYLVRSVKDYLSGAVPGEVYVWLDIFAVNQHPGKAQNDDLAQLNSAITNASGGTLVVLDGQAGPLGRVWCLFEIWITVRDKGLGSLHLLTYGFTNNDIRDCFQAIDVKTAKATNEDDRQRILKYIERTYDSLDEFNEMLKLLFLLDPLDYSSDIKEMLRSITFAVNPARTLQAGGGAYDGGYGGGGGYGNGGGGGYGNGYHGGAGGAGSSMSGNLDPLKSSSEAAAATAQAVAQVAAARDAWQIPKVVEKIRGMDPMAFQKDSRGGGGRAVAGPSLMIVYGVVGSGKSTFSASLARIAQERREREARRLLLAGGGLLLLQGGGGGGGGGGAPLGDDPLSALDLPEVQVDALHFCKQSDRRRTDPLRMLKSLAYQLATNVPEMRPIYTSMPSESVSKISRLEEAFMELLQRPIQDYLEGSQLPSGPAAAAAAAAAAAAAAGGGYGSAVKGRGRSKQLVLLIDGVDEADGRAGALDNNILRLLREHFPKLHPAVHIVVSCRHTNKADDPLAGLKGRYDKTRTTVYDAAMELRQGEHVRKLLEVKLHPPGCRLDPAQCSMHDPDTLRAAVTMVNDKSRDSMVYIKVVLEHMSAVVKEQLKRQREEKEVLESIKAASDIAALMASLTHGGAGAGDKLAAVAAGGAGGGAANLLQLAAAMGLNGGAGGTGSGGAAGVNFMAVGSEGSMRSGNTSSSHTPLDTEATAAAIGANIKAILAERMSDLATGGPEALVRLEEEVAAMVRGRFQAPGFSPSELAKSLAAMGGGGSPHPPAPSAARLGSPGVDDSNRITSSAPSMAARRNMSRSLAALSRKGTRMGAGGSNAAGSAVAGGGRAGGGRGDTSTPGSHGSHGSHGHGHGHDSSAEDDNFRWNWQDIKNLPNGLDAAYRQIFIGCFQKLAPQSHAQVMKLLQVLLAAREPLTRNQLLSLQLVAGVRDLHKLPGWGVLFYERGLHGGWVDVIFHMHKSLFDFLSNRRAAGPFYVDAVRGHKLIAAQLFKEIMTAQSAGPAFGGGGGGSGMSVSALSGVVGGASESLASSAVSAYTLRYAVTHLALADMLEELSQLLLNFDFWETIFEKGLGLEVLSDLIQIRGWELPKDSIAEADVVAASSTVVSHVIRWLQRDGAMLKQYPKAVLQLATDTPVNSLVSKAALSYHRRPAGRLINKDAGWPSNLMTLENSAHRTNSVAFLPKETQQQQQQSSSGGGGGGSTGLRLVTGAGDGVVRVWDMRSGDLLFAMQPPLQAYQGTPPAVKCVAVASLPDGTTLVASAGKDSAVRLWNVKTGQPSAELGKGNSVMTGTVRALAVSPDGRIILTAGDDLALRVWTPGKAEDEAALAASVAAAVAAGHVPEAAAAAAGGSAAAVAAATAAVSAAAATGGGAGRSTPGGADTDFDLGKLWCSPTITILQSKHQKIIRCIAFSADGSLFATASDDDASTNAVALCLWETAGFKVRGILRGHINSVKCVAFTPRPVAVGDPSAGGAGGGGGGPLQHVLASGSADRTVRLWHLRSPTPGKAGEGTADARAAEGQWALPNPTLQGHTATVRAVAFSPDGVKMASAGEDRTVRLWGIASRQQLAVFHGHGAVVVSLSFDSPDGLVLASCSETEVRLWDTSNYPQVTVMHGHESGVNTIGFSSDGKYLASGSDDSSLAIWRDCGEARWIKGAAVPRDAAGKAGHSGSIIALAFSPADDEAMGGGGGGSTGSAPLGGTRLLATASADKTIRLWLLQESKPLTDDQARAITTVANLLRRKRAAAASRTSEEGEADDVSGLLANRRNKKTDPELEPPPLHLEQLCVVQGHDGSVRAISFSADGLLLATGSNDRTVRLWAVPPSGGLVARTQAVMPFLVLSGHTDVIRCVAFSPVSSSRLLASASEDRTVRLWHVAPAGQGVSRLHCELRGHDSWVIACAFSSNGQRLATASLDKTVRIWSVSNGEQQLVLRGHSAGVTSVAFSPDSMTLVSGGADNTVRQWNARTGQQLAMMQGHIGQIAAVAYSPAGNAIGSGAADATIRLWDATRGQQTSGVQGDVGSFQTVAISPDDKFVSSSADDNVIRLWDMSSGEQRAVLQGHTSWIVGICFGYQDCEDGDPHLMLASCSDDCSVRVWDCETAECVRELRGHTGSVRAVAWEGLKWNFIASAGNDYTVRLWNVPRGSQVDLFKGHTDVIRALAFSPDGLMLASAAEDTTIRLYHVGHITGSDANRPDWLPALPGSGVLLKGHESWVLAVAFGPRKSESHAARLLVSGSWDQTVRLWSLPAEGGKEPHCYATLRGHGGRINSVAVSTYGGHEIIASASNDSTVWLWRRTGSAAPSPAAAAAAAAAPKASETGEGGGEGEGAAKEKAVVPAAAAPAEGAGSAGWEPVAKIRGHAGHVNAVAFNTKGIRLASASEDETVRLWDLLPSSSGDDKAVTAIQVRDFKGAQGSITVLAMSPDGQCLASGSDDHTLRLWSTRSNQQLMVLQGHGAPVSALAFDDEGAILASGSVCGTVLVWAKDAAGAGSREGWSQVAKLELALQVPDAAVSALALTHYFPTAGLPSTAADGSTVNLAPSASPGPGFIMSQHQHQQQPQQLTSLSAIPGTKLLLACGTKPREMQERGLFAAGAAHHGAGGFGGAGAGGGRAAGRRGGARSGGHGGHGGGEDDFFGGRMISSSLTLWDVDAVRAAAALSVQLRGAGGAGGGASKPYRTLKCQSAIAVTTFNDSGEILASSSFDNMVYLWRPEQQNPVARLAHPSAPDLATSLAFSQDGLLLVAGCRYSERVDVYDINKAIQSTQMRDGSVTAPLPLGDLDGSGLDGTSVATCDTSGEGLADRQVIVCRSGYKNQATHLQVLELPPPADVAAALEAAAAADAAGGSGTGAGNSGNQRVSIMTALGGGSGNAAGQQPGASGGGGANATRMPWEVLEAAGLAPKELANVYTVMPIQQMACFEDLLVVTNSHSLNFYRLGAAAAGLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCQ7</accession>
    <name>A0A836BCQ7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">CBM20 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_001056</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454014.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BCQ7"/>
    <dbReference type="OrthoDB" id="533354at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:2001070">
        <property type="term" value="F:starch binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd05467">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.60.40.10:FF:003359">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.1490">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.10">
        <property type="entry name" value="Immunoglobulins"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013784">
        <property type="entry name" value="Carb-bd-like_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002044">
        <property type="entry name" value="CBM20"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013783">
        <property type="entry name" value="Ig-like_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15048">
        <property type="entry name" value="STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR15048:SF0">
        <property type="entry name" value="STARCH-BINDING DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00686">
        <property type="entry name" value="CBM_20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM01065">
        <property type="entry name" value="CBM_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49452">
        <property type="entry name" value="Starch-binding domain-like"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51166">
        <property type="entry name" value="CBM20"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="CBM20" evidence="3">
        <location>
            <begin position="90"/>
            <end position="200"/>
        </location>
    </feature>
    <feature type="domain" description="CBM20" evidence="3">
        <location>
            <begin position="279"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="214"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="409"/>
            <end position="450"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS51166"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2454014.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="602" mass="63932" checksum="D99A49BA008D24F6" modified="2021-09-29" version="1">MAAAMKCQAPSRAQVQQRQRSHVSMSGADAGWQTVPAARDVTRASAVSRGATAAAGSLKASTPAAASTITAARGAALVARYATSTASTLPLDGPALTVRTRVVVPYHPTSHGQQLVLVGSCEELGNWDPKKGVKFTWCEGHSHEAELELPVHTNVSCKLVVLGEHDSNTWEPEANRELLLAPASLASRAAGYTMIMHWGFPDCVQVMANSLRRGTGVSPGSSGRASPGLNGSSGGVMGNPLIAGMKKALEAASSRERFSSVISGSASWEDEFGADDEPVLTQCQVTVLMPKNGPKLKPEQSLVLVGSSAALGRWDPANGLPLERAGEDSPMWTSQAELPLGDSLQAKVVVVDGVSGKAEIWEPCENRSLARYRGSKPVMVTAYYGVAPTHSLEVDRLSAAAAAGSPQVVALLRQQLANTSSQLDGLRRERDDARKAVADKEQAMKSLEGKANNAAPGRFEMVHLAEQLQTTRKLYEVTKKEAMELGGTVGVTRQLCDAAKKELAGLSKQLIAAQKAYEALAPQVERMEKQLASTNRAFDATKPELAALEAQLERARGLFDRTLSKIEAAKSLASGSSATASGDYDLTRRRVDSRVREMQFAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="20" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCV8</accession>
    <name>A0A836BCV8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="9">Gamma-tocopherol methyltransferase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_001154</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Alkaloid biosynthesis.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the class I-like SAM-binding methyltransferase superfamily. gTMT family.</text>
    </comment>
    <comment type="caution">
        <text evidence="6">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454115.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BCV8"/>
    <dbReference type="OrthoDB" id="8300214at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008168">
        <property type="term" value="F:methyltransferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009820">
        <property type="term" value="P:alkaloid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032259">
        <property type="term" value="P:methylation"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.150">
        <property type="entry name" value="Vaccinia Virus protein VP39"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050447">
        <property type="entry name" value="Erg6_SMT_methyltransf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025774">
        <property type="entry name" value="PiNMT-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029063">
        <property type="entry name" value="SAM-dependent_MTases_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068:SF11">
        <property type="entry name" value="GERANYL DIPHOSPHATE 2-C-METHYLTRANSFERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44068">
        <property type="entry name" value="ZGC:194242"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02353">
        <property type="entry name" value="CMAS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53335">
        <property type="entry name" value="S-adenosyl-L-methionine-dependent methyltransferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51581">
        <property type="entry name" value="SAM_GTMT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0017">Alkaloid metabolism</keyword>
    <keyword evidence="3 6" id="KW-0489">Methyltransferase</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="5 6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <keyword evidence="4 6" id="KW-0808">Transferase</keyword>
    <feature type="region of interest" description="SAM motif I" evidence="6">
        <location>
            <begin position="84"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004913"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022589"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022603"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00914"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2454115.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="9">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="128" mass="14010" checksum="8C63CC57F2AAC357" modified="2021-09-29" version="1">MMVRAGPLETLVKPLTTLGKVSDLKSGIANFYDESSELWENMWGEHMHHGYYPKGAPVKSNQQAQIDMIEETLKVAGVTQAKKMVDVGCGIGGSSRYISRKFGCTANGITLSPKQRPTSTAKNHALVW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BD25</accession>
    <name>A0A836BD25_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_001370</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BD25"/>
    <dbReference type="OrthoDB" id="530736at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="63"/>
            <end position="73"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2454344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="80" mass="8541" checksum="EFC0F31EE665554A" modified="2021-09-29" version="1">MTGAQHSAQHHTTPVTYLLPYRGNKQQTGDQLKEATMGGQHGTESAATKAHHSMQEATQSTGHRADETAEKAKHGLGIHG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BD49</accession>
    <name>A0A836BD49_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Fungal-type protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_001352</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454325.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BD49"/>
    <dbReference type="OrthoDB" id="2436248at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2454325.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="3">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="569" mass="61848" checksum="1CE48A0A03FCB5AC" modified="2021-09-29" version="1">MASPVTACAERSLASERVVTLYIDSGTAGVDLLETLRTLPDAELQVLWTVWGPLAARNAPEFEKAFVERSLRTSAASLGVGTAVGAADDTTATRLRACLPPFAARTLWRGPQALRECLAERITPGLPLPASVARRLFQQNAELRGPLVSTDDSQEAASADALAAHVRHVMVDFEPVVGSEMYTGHVTRAVLEDTLRLVMRYLPGPRILMDRNRVGTSGATTGNLRPDFLAWVNSVLLLKGEEKAAASELQHAVQELTTKVSDAWAAGLLPHTPLPSMLAYAAAGAVLQFFCIEHVGSGGVQATPISGIMDLTTAPGRLQALTASFNIWRLLAGYTSQGPTAPIGMGQVVSSPDGLRTYCLLPGFFRKSIRQFSLHARYTSFKLLQELYGKMSEQKHRLSIIQACDVNGVAGPRLQQHDDTYVVHLAPVGQPCMGPPATESDLACAVLGVLSGLAALHSEGYVHRDVRWPNVIFLPAERRWLLIDLEHAGQEGCDCSKDPFPLPFWSEHTLDDGKYTAQSDLRMVAEQLMSHLSFPLEVSGQELRRRLLGDRFSAAQALRHRWLARASGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835S8M0</accession>
    <name>A0A835S8M0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_015452</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000235">
        <property type="protein sequence ID" value="KAG2422334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835S8M0"/>
    <dbReference type="OrthoDB" id="445301at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0042765">
        <property type="term" value="C:GPI-anchor transamidase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016255">
        <property type="term" value="P:attachment of GPI anchor to protein"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007246">
        <property type="entry name" value="Gaa1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13304:SF0">
        <property type="entry name" value="GLYCOSYLPHOSPHATIDYLINOSITOL ANCHOR ATTACHMENT 1 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04114">
        <property type="entry name" value="Gaa1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF101447">
        <property type="entry name" value="Formin homology 2 domain (FH2 domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="65"/>
            <end position="86"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="956"/>
            <end position="976"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1060"/>
            <end position="1080"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1133"/>
            <end position="1152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="191"/>
            <end position="216"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="248"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="378"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="429"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="904"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1013"/>
            <end position="1044"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="24"/>
            <end position="47"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="196"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="248"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="378"/>
            <end position="392"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="393"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1028"/>
            <end position="1038"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2422334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1164" mass="111232" checksum="64F50684D5CBD08B" modified="2021-09-29" version="1">MDRAHETGPVGGTGDATEVDLANSRAPAASAPAPTPGPSASSPVAPSRSREKPLLLLLAAVARRAHALGLLLLLAAAGGLLALPALDRGVRFEEKGLLAGLAAPTIGQAAAGGRMMRAARRIARSATAATAAATSAAATSSRGRAAVAAWQSPGAPAALAAALAAAGLAETQLTRPRVRLPGPLLPRGFGAGAGAQGANDSSSAYSSSGTAGGGGGTGWCRCANVHTIIRARRGDGLEALAVVTPVALSPPPPPPPPPPPFSLSSSSLRWSSSPGPAAAAAAAAAAAAAAAGAAPPSAAAAPWGPLPDPALDGRAQTAAGAELALAAGAALALHLAAPAEAGGGGGRWLARDVVWVVPDWSCGVSACLAAWVDSYTGSSSSSGSSSSSSGSSSSGGGGGGSGRGTGAAAAGGGGRSGGGGGGVGVGGGGGGGGGGRATAAAAPKEEVERGGSGVAGPEVGQEAGGEEAEAEVRLRGGVIQQAVVLEVLVGPGGGPQAVELVVVGGGGLLPKLDLYWLLRYMFGWPTTPSLWRDDGRLDGAAAAVAAAARQLTGGSAGAAAGFASRLLHGLQFAWQQAVGRPGGAAAAFKEAGVDAAALRLVPGRHDPWTGAGRPIRATDPDAAPYYHPSAAAAAAAAAAAAATAAVEERGLALASGLELALRSLNNLVERVHHSPFLYLLTGLDRYVSVERYVGPAAALALAVQLQAAWSMRVVRLATAAATAAAAAAAAATGGGGGGGGGYGRGGGSAAACGPAAAAAALWGEAAARAAARTAACAAAAVGLRALSCGDGPAAPLLQRLLELAPAPAAAALLRPLHVALAAPLASPAGAAAAAAVLLGASAAASGAAALAGRLVAAAAAAAAAARSRGRRTAGGSSSRSLQAACGPSGRASLGSAVAAAAGGPPRGAANSAQPAAAQQAPGADLDAGEAATTAAAAAAAAAAAASLSLRWHAERVLVVTATAAALAALVCLNWAAAAAAGLYLAKLAAAQGLAAAAGYGCGGARLQLQLPEPPKKRRTQVQQQQQQQEEEQEQEEEAAVAGPAQGQLTAAASLRERRSLAARCAAGAVWALGLGLWLVASPLTGLLVAVALAEAVGLGGGLASGGGLAAGVDSALGWGLGPGLCSGLSAPNYWFTAVVAAPFWLFGLEGWLGQLELQLQRLAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SHM7</accession>
    <name>A0A835SHM7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_014592</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000101">
        <property type="protein sequence ID" value="KAG2427372.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SHM7"/>
    <dbReference type="OrthoDB" id="10320496at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004988">
        <property type="entry name" value="DUF273"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03314">
        <property type="entry name" value="DUF273"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2427372.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="123" mass="14086" checksum="1083F1A15B6207A9" modified="2021-09-29" version="1">MNCYCALHGYGYHLEYMNPLPQRHLFQGRLQYFFKYLPSYQWVLMIDADVVPLNYFQSLADLLDDSYDVIVTDRDNGEVQSSYFVRSSPAGEGFVRQQLALSDTKAHANYDNGDLLQVGLSAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SJM3</accession>
    <name>A0A835SJM3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_014408</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000094">
        <property type="protein sequence ID" value="KAG2428392.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="550265at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF289">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE VIK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="774"/>
            <end position="797"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="1139"/>
            <end position="1663"/>
        </location>
    </feature>
    <feature type="domain" description="Protein kinase" evidence="4">
        <location>
            <begin position="2210"/>
            <end position="2555"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="581"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="942"/>
            <end position="963"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1281"/>
            <end position="1300"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1312"/>
            <end position="1343"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1381"/>
            <end position="1428"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1568"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1633"/>
            <end position="1666"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1707"/>
            <end position="1760"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1893"/>
            <end position="1937"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2066"/>
            <end position="2141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2174"/>
            <end position="2210"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="2242"/>
            <end position="2330"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1312"/>
            <end position="1323"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1381"/>
            <end position="1411"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1581"/>
            <end position="1594"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="1636"/>
            <end position="1654"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1912"/>
            <end position="1932"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="2247"/>
            <end position="2263"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="2264"/>
            <end position="2274"/>
        </location>
    </feature>
    <feature type="binding site" evidence="1">
        <location>
            <position position="1166"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2428392.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2576" mass="257934" checksum="16FFE15FA1175382" modified="2021-09-29" version="1">MRTWQLLGAPSPFARAAVALVNVTVALPTCGPLWELVVSECSLHVSRFWPASGLVAGPAFLFFPRLKGAFSSADNLNVTCPLGDWQALLTSSATVPGLAPCGTATVHSGQQLLDALEALQPGHARLLITLAANITLPASPTPPREDNTADDATPLVELYRGGWFNRERGVPQPVLVMADLQTLNAPSGPPSTWPLGLLSFQQNYLGADRSGARGIQRIGLRSWLVTTVAEAAYIRLWYTGWLADSADGSGQQHASSWMAALMTPVTQVRDEDGGQSSVSRLSFMLSYNTSTSVSARTAPHEYDMWTGLMPASAGSSQAAPSLSLPLLPPASFAAAASASQLLQLLQLLQQDTWARTVGPRVIFLLSNVTLSKDAWPEGGAALRYPVVLAGPASGAAVWLDVAGMSLVTPPVIMTAAYAAAAGGGAGSTTNMSSGRGGTMAGDSIISLMRLRVTGLLPRPVWLLRQRGLINTARTALLNATAAAAGSGGLMGQPLAAAEGSLYPALSSWLSTCPQQDGMLLTALPPSPVVGDLLLQPDANATFVITIYNCTVETSQDVLELMAAFSLTDRLCTATVSANNGASSAATSTGSGAPAPAGSSATDRWYPWRARRAVVCDLASVNNTNAASSTSSRNSSSSALALLPAGLATALSAVLRGEMRANTGEDAAAYLLLGSRGFRDDGVAALTFTAAGGSLHDLSLRYTSIVAVTGGGGSGGAGAGGESAATCSPLALTSAIVSDTAWLANVSAAAAAAGTATAAAGSRARAAAGSGAIDALIGGVVGGAVAFLLLLLCAICAMERLRRRQRQHEEEAAEGNKARRGCMCLPGPPQARPRSPSMVAGGGKSEAVRHHYDTAQSVAGDGVRVATVAIQLMEAVKAAGNDVQQQSVAAAVPPAAAAAASAEGAGDSGAAALAAFAGGNGDSPQAAHGDSSWGFTLTMHTSRHEIHESSSRGGGGGADGGARPKQATMYDIMMTPRGGGGGLHGSAAAAGAAAAQAARGTAEIVPDTEGAPVALHWQQQQHKQQHKQGGMQGRVLHVLTTPGLPAAADAIVTTAVQAAAGGGGGAATTVAALGSPSHTRNAATTGAGVSLLRQAPSGQYTRQVSTTFAQMEMRISQLKEAVAAAASPVLASQGSGRGSKTTPRLLGKGAYGVVELGGWKGTLAAIKTVVQLVSDARRLERLASEVAIACSLSHPCLVATYDYSLEQLPLGTAAGGAGGGGGGGAMLFAPLAPPTAAYSSTEGHGDDDGTTTVRLRLVMEYCEGGTLKEALLQGLFDSEPPAAASTLTPAPSTAGATGTGGTTAAAAATAAAGKPGSTTAAGSSRGIIASKSPGGRPQPQQRVLQTQQAVAYMPHPPYGQAPSAAVAEIHASYSAYVAAAAASDRQQRQQQQHQDPAAPSSASATSSSSVPAGNRVDSGGNRRSSIDDTRPRVRNLPLALVAARDILAGLTHLHACSVIHGDLNENNILLRKASPLLPVAASAAVASAVASAAAAEMAASTTNTAPTPAASGSLPASVAAAVMLTGSTDTGSAGRLRTASTAAVGSSGGVSNNVLLGVMAAIDQRLPNYTGESLPPTAREGQAQQQQQTSHLAPAAAVAGGGCSVSAYGGASRGASSTSSTRLLLRQLNQLADVLLRPPPPPQPQPPLQPPPPLPHIEGGHPALGTSAAGTMAHAFLSQRQAVLAASSSAAQSGALCTVPHPSPAVITGAAAGTDSVSNSHSSPLRIPGPWPRAPQLAAVASAHAADPQQQQQQGVTTSSQRIEHANAATKDKMSAAAAAAATGAAGAAASSLVSPFTAPPQDLQLYSFSANTTNTVGSHAHALAAAPGYCNAGSGLAPSCSNDGPGATAAAAAACCGKVPGDNLDKQQQHDCLRKQEVALAAMAALLRDNRLPELPEQHESSGSSRSRHSSSRSSSPSGRGDDNNGAAAAANEPPPLKPQQQLLLSVAAAAAGPAAAAARFGIPAPAPAVASFTGACGDSRVSSNQTAARLAPSNSSAAEPPPHLVAALLASTTTAATATTAGPSACLSPFTAPGSRSVSASSSVSFMDALMVMSSAAAAEGLPGHLGQLPQLPPPVASGRGELAAGDEESMPVAEATLPGRPTSAGRDSDAAGGGGSSGAATPPNPLQRGPTEEDCEQEQVHHHAYATFDVGGEGLQLMSRRHAAALPAAPTAASAASGGGVPGAATTEAASQPLPANRYAKSRPPVRPRHSQQLLLGAVSHSHLRLHPQHRTPTAAIIAPRRSSSKALQQQAIASSLAPAGSSGGGDGGGGLLLQAPVYPSARSGNTTRTRTVLGGAADGGAGNHQHQHQRRPASGAGARTSQVPPAATPAAAAAAAAVVYPAGGGLRRMASLQSPPLSVAASTARPQSAASLHRLLLWQGRIADDSSGNGTSGAVATAGSGAAARMAAAAAVAGSAALMESAAQLMAHVFKISDFGLSMHVPPGDQTHISGVFQGTPVFTAPEVVFQGRLSPAADMYSFGVVLWLLLHGVSLRGAGLPMSLYRLAPIGPELLRRLSPELPPGARQLLAECLDLDPGRRPTAAEAGRRIMKLLEEALGLGLASVVLSIERVPLG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SK29</accession>
    <name>A0A835SK29_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_014652</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000103">
        <property type="protein sequence ID" value="KAG2427006.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SK29"/>
    <dbReference type="OrthoDB" id="10639427at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2427006.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="76" mass="8236" checksum="D9ABA1B1636F9B8F" modified="2021-09-29" version="1">MEPAAQRLEDAVAQAAAISEQEWVRRHKARRAAGDAEDWMHAVATPVVKRRGGARRGGPFSRGVASRLTIACLGEQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SLR2</accession>
    <name>A0A835SLR2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Cytochrome b561 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_014054</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000086">
        <property type="protein sequence ID" value="KAG2429398.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SLR2"/>
    <dbReference type="OrthoDB" id="544907at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="CDD" id="cd08760">
        <property type="entry name" value="Cyt_b561_FRRS1_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd09631">
        <property type="entry name" value="DOMON_DOH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.120.1770">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006593">
        <property type="entry name" value="Cyt_b561/ferric_Rdtase_TM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045266">
        <property type="entry name" value="DOH_DOMON"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005018">
        <property type="entry name" value="DOMON_domain"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130">
        <property type="entry name" value="CYTOCHROME B561 AND DOMON DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23130:SF171">
        <property type="entry name" value="OS01G0895300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00665">
        <property type="entry name" value="B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00664">
        <property type="entry name" value="DoH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50939">
        <property type="entry name" value="CYTOCHROME_B561"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0249">Electron transport</keyword>
    <keyword evidence="7 9" id="KW-0472">Membrane</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0732">Signal</keyword>
    <keyword evidence="3 9" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="6 9" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="2" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="369"/>
            <end position="391"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="412"/>
            <end position="438"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="458"/>
            <end position="477"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="498"/>
            <end position="519"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="9">
        <location>
            <begin position="525"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="domain" description="Cytochrome b561" evidence="10">
        <location>
            <begin position="314"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="34"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="276"/>
            <end position="302"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="688"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="34"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="8">
        <location>
            <begin position="64"/>
            <end position="75"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="76"/>
            <end position="105"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="290"/>
            <end position="302"/>
        </location>
    </feature>
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        <location>
            <begin position="688"/>
            <end position="736"/>
        </location>
    </feature>
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        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022982"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50939"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2429398.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="773" mass="75717" checksum="912234C4CFBCFFC3" modified="2021-09-29" version="1">MPGATSMTFKATTATSRWGSFLQGSTTLPISASCGCTSSSPAPASAAASASPSPKPSPSASSGPLPPTASTPSPSPAASSSGSSSDTSSSSSSSRSSSGSSTDSASASTAAATTCAPSTLGYACSLALPGGGGEALHWTAGTAAPPDNACTRSSSSSSSATSTSATASSTATANLVHFALSSPQSGYLSIGFTQRAGMMAPANAVIGRIASGSATVETYYMTSYDLDPPTNNGWAAGAAVLSTSAGGTVLCFTVAADGAAAAAAAASGHRRRQLSTAAATAATMPRRSLAATTTTTTTTTSTTTAAAAAASSSITNALGLNAAALELIWASHRSADLTATHSRWGGVSLNGLSGAAAASAASRRRDQMLALHGALAAAGWVLLVPLGLLLARHRRNVSALRRAPRVVVVAGASWDMWLALHVGCVFLGTASGAASIGVAAAELRGSGASDGSTLAHRVTGWAVLGLAVLQMLSGGIRPAPGASRRRLWTLLHANLGRAAALLAWSCTGLGVFLAVTRYSQDLTAWAAPLAATLALLLGAELGLTAAAALVAEAAYAAAPPPPPPGPDALAALLPPAPAPGLPVVGYPASAVNGALPSSQQQMQMQMPVQQQQQQQQQQRYQGVYVLPAAAAASTGTASANQMAQMVCGNGGGGGGGGGGSSRHQLFQPYQQPYHYQQEVTALPPITATGAASGATADGTVTTRPPSSSRQAQAAPRPPSAAGAAPAPAASSASSSASGGGAVQLGPLRRQQSPPSLGDSGYGDGALGLRGNKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SMT5</accession>
    <name>A0A835SMT5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_015348</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000152">
        <property type="protein sequence ID" value="KAG2423320.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SMT5"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="83"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="42"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="104"/>
            <end position="129"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2423320.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="157" mass="15892" checksum="B17EB5D0C97FFD3A" modified="2021-09-29" version="1">MADQGGAGPSRPPRLASSAKGPQRGRDADEEERDATCDAKRKQSLEVLKKYQEQRRQQLQAQLAQLEQAEWAAALAVDDAALAGGGEPAQGLDTSGATSGGAAGAAAAATAVGGAGAAAAQLPLQQAGSDPSVRGNQREASHDSSSVNVQQLRAPPR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SMW3</accession>
    <name>A0A835SMW3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="3">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_015337</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the PI3/PI4-kinase family. ATM subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="3"/>
    <dbReference type="EMBL" id="JAEHOD010000150">
        <property type="protein sequence ID" value="KAG2423365.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="381190at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005694">
        <property type="term" value="C:chromosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000077">
        <property type="term" value="P:DNA damage checkpoint signaling"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006281">
        <property type="term" value="P:DNA repair"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000723">
        <property type="term" value="P:telomere maintenance"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056802">
        <property type="entry name" value="ATR-like_M-HEAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050517">
        <property type="entry name" value="DDR_Repair_Kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057564">
        <property type="entry name" value="HEAT_ATR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003151">
        <property type="entry name" value="PIK-rel_kinase_FAT"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR014009">
        <property type="entry name" value="PIK_FAT"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139">
        <property type="entry name" value="ATAXIA TELANGIECTASIA MUTATED ATM -RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11139:SF69">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02259">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23593">
        <property type="entry name" value="HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25030">
        <property type="entry name" value="M-HEAT_ATR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51189">
        <property type="entry name" value="FAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="7" id="KW-0227">DNA damage</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="5" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="FAT" evidence="12">
        <location>
            <begin position="2262"/>
            <end position="2935"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="525"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="632"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="1568"/>
            <end position="1630"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="2030"/>
            <end position="2056"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="11">
        <location>
            <begin position="525"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="11">
        <location>
            <begin position="571"/>
            <end position="580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="591"/>
            <end position="600"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="632"/>
            <end position="642"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="651"/>
            <end position="672"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1568"/>
            <end position="1582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="11">
        <location>
            <begin position="1598"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="1615"/>
            <end position="1625"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010769"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022763"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS51189"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2423365.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2946" mass="306698" checksum="1DEF6E6D4757A917" modified="2021-09-29" version="1">MNSQLLLDLQAALGAALSSGSQNSTPASQSNDPLVVKLRNGVGMLLDACAEASRNSTAAGVEQDVVTVLSVAEFVVERLPMVFCRPDSLEVGPVRSLLGLLLAGASRFRSLVERMVSLLLRMLHLAPAGLRRALLLDLAEGAMELLMDAEQQLVVQALDQQALCCDTNPFSATTTATNINGDSSTVSLGMILTFEALLLRCGPTASSAAAAAAAAAAAGAGAGPGEGPVATAGCCVLEVQLDQYDRCMAASEAAAALLSSLVVYRSELVAPLVPHAVTQVLLQLIVAATQSPSTQTQLVLCTARIAAASEGTGFCEGLLQVALTLLEAWTTGVIALPEGGSPAPTSAGTGEEPQAAGTMAAASWHAAVSGAMQFCCAALEHRGTVALYADRLLQLCLRHCAAAASAAAPAAGGPPYSPTSPYSPYLVNLLAVLEDCPHLMPVAVRDGLMEVLLRLPPHPLQLATAGKPAVRAPTPHTQPAAAAEALRLRCAQWLAEPQVTAAIVDCVAVALGLPAGGVIPKTHVQSGVMSSSRDAQQVDSDTRVAPKPGRADMPGLERTLSADADQATLPIKDEGTERPTKRLRRTGAIGGKQQASQAAGGKYGNLQDMFASQAAIKQRALAEARTARDGGTQLAAPAAGAEAAGGGSSGDGRVAVGNARNPPAPGTARGPAGRALTAAATVVVQLMSAPATNPTPSPPPLPLSLARRQLLQSQLELLGRALAELLPLAGPELLLLAVRSLTELVRQACGAPGRAAGSASEAAAPVCDAAALTEPGLQAAVYRTTCVLVLAVLRALPELDVDLSNTAGVTAGVAAGTAGGSGTGGGGPRRGATVGADGAWAAAWGSGVQSLVDTALALVNPSPEAMCVDPESQSAEGAAATTAALVLLRTSLCTAGYSLAVSALPSACHPASRSEGLLVAWSGQCTALEKSLKRFFSATGVQGDAGLAIADSLGSKRADASQMSSAGDGRRFLTGVLGALGRNLVINLLPVGMLLPFMDFTDQSSTDRHVALSAIRMGGPDGIAATMLDEFARAVQCARSGQASIKVLEAPGLGAVAALVGGLQAAAELLAAKQVSQLARASLKAVVLGLRQLLVSLRQVARELALHSGGSGPELQPGARAAAAALLAAAASLPHLPEQLWLGLAADTLPHADSSGGGVDDEPCGSTQSAWPLLNRFAKLVEPWLGQAGGEGPGSISRAPAIAQVQVLTALRDVVHVCPASSAAKANATFAQAVFAALKSQHGIVRAAGTSLLRVCLRSGASADIFKAPAGSTANRAVREVLSRLHALMGDLRPDAGAVVRCSLLFSAVGLLADQGEGEAGLPGLTWRDCAPQLLLMVLGCLGAEDQQVRAAASCALGVLTAALDQSAQQLLLEGSHATMVLNTLGGSVLTSPRLLPELCRLLNATDAQLVRAIVPHAIGPLCCSNRLDELRELARRLDLPPAELFTLHAHHAYAYAFWKEPAAFDAFMERVEREVLERGHGDVVGRISMARMLTKQTIIMAGEPSDSWHVTGSLEPPAGLHERIEVFMRAIAAESREMETDDFVQELLLGEVAAGLFELFGKQLAQSPGSAGGAPAQAAGSKPEGRGGALLSPQRARQQHHHPHHHQSGHQHQHTVQQQQQQQQLVGSDVHHNHRTPTVESVDAEALQALRSLCVLVLMLGKHLPGHVPPVMVLLTAAVSRAIASSLELQLQSLAGWRVFLRCLAATAPSLLERVAVQASVVLLPLLQSPYGEVSSSAAGVLTLLVVDNKEHVRKALSRMPPLPAEVPGLEQVAAVLQEELQLADRRKRLAQLADSLQHDSLEVRHVALGELRFFLTDQRAFMCELVQRGCSGRTAVGAGMSPESSRAVAAGGAAQKQLGKRAAGATAAKGHSGAQGAVADAALLAQLLSALLRCCENTVRTRLGKDIRIRCGECLGLLGALDPARVAVERRAPPDLMDQDPSDAMALEAAAPAGSGAGATDKGSGVEARRVVAKSGGASAGGGGQYALEVALVENLVRVMETTGDLTVYRFTSYALQCLLQHYTGGSGDGSGGGPARITSGAAGAGGRAGAASPEPEGLYWEIRSDIRPLVKPYLTTRYTLEDVGRGGRPEVDSWLAGNPLFNAPKRPSYRRWMTLWIRAMLRFAVGPHQAAFNAMMPVMRQDLPLMSFMLPQVVHAVLVSGNATATEAVRREVVAVLQAGAAGPSEADGQLELYLQALFGLLDVLGRWVKDAWQAVGATGSTQAAAQAPGGGGGDSSVSELPARAQHVRAFIESIPMETLARAASRCGAHARAVQTFETHMRSEAIKAHAATQSRSATSGGLNPAADISRPQYKALNADVSFLLEAYGQLGEPDGLAGLCAMRPSGLSEADQVLVAERAGQWGDAMALYESAMRRDGDGGRDAADALSSEELLSAAGAALGAPGRSSCFGAAALRQGNQPVLGADSDDSAGSGALCSSQAGYVRCLLAMGHSQAVLSSVDGLLARGTCTPSAAKQFAALGVAASWRLGRWSRLRGYLHAVEVAGPEFGEHGEQQQLMPGCTPTATGLSPSDQWELDIGHLLDTLQRGDWARVRDLLEGYREESMAVLPALAQESYVRAYPHMVRLHMMQELSDVLSLLDPSCGWTGLSANERARRLRWPDRMASTQALLPTQEPLLSFRRQLSALMGDREAEALAVAGHRETMPRERAVLEAASRGVGAAAALESAKLLRARDLHHRAASELQSAIHELSAAHAAMSPAAADPKRMLARLKLCLARWSAGQGGRAPAELRRLFDDALNADNAWDKPHFHYARYLDQIYQDARRRQTGAWEASPFGGRVKVVIGDERQYYEYLPDVLRHYGEAITKGQKHVMQALPRMLTLYCEHGSDQLARGTNAPRTGRESRAATDVLNTMKLLAATNIAPPKWLVALPQLISRIAHANKEVSEVIRIVLVRLGEAFPPPGAVVSCGRDAAAQFAKRREGCG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SSC2</accession>
    <name>A0A835SSC2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013029</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000068">
        <property type="protein sequence ID" value="KAG2432309.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SSC2"/>
    <dbReference type="OrthoDB" id="337870at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="63"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="35"/>
            <end position="48"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2432309.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="80" mass="8319" checksum="1329A57031E195FB" modified="2021-09-29" version="1">MLLQHRLASRPARAAGSRRGRPLPFQGSRLPSHVAASAAAQVAEAPAASTSGPRPGLDGRPNIMSLLRSRGLIQEAAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835SXK6</accession>
    <name>A0A835SXK6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012535</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000061">
        <property type="protein sequence ID" value="KAG2433606.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835SXK6"/>
    <dbReference type="OrthoDB" id="10261302at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0071944">
        <property type="term" value="C:cell periphery"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004620">
        <property type="term" value="F:phospholipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046513">
        <property type="term" value="P:ceramide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030149">
        <property type="term" value="P:sphingolipid catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393:SF6">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12393">
        <property type="entry name" value="SPHINGOMYELIN PHOSPHODIESTERASE RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="1013"/>
            <end position="1036"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="28"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="301"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="394"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="540"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="591"/>
            <end position="611"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="760"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="394"/>
            <end position="408"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="415"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="540"/>
            <end position="553"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="554"/>
            <end position="564"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="591"/>
            <end position="610"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="774"/>
            <end position="784"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2433606.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1053" mass="107605" checksum="931C89B883C8AB8A" modified="2021-09-29" version="1">MATDADTPGHSAVAPASGSDPPALDDPSRVWLPEIVQRIARYLPPNDVALTLRLVCRSTAEQFRAPAPAASAAIAGATASKAPGTGLEYSSGPAASDPTQHPQQHQKHQKQKHVVLLTQPVPHHAFARHFGPTGRGMSALTRDCRRRLLAEVAASGVLPNVKLLLDVWPVHCPLSHRALAAAAGVGQLEVCQLLVARGCPLGGEALDAAVAGAAPGLSVRAAARAAAAAERAAANSTADSGNSNGYGSSCFDVWDQRRKQQQRATGCAAVVEWLLSLRAARVAEARAAAAAAAPAAAKQAAGARQADAHQKGKRLKGPGAEPEETEEEAGLSPGYCDGCNPLAAAARGGDVAMMYRLMALLPHKLYLASLLEAAAEGLPLPHLRTLHALLQPQEREQERVQEREREWVEQEEAAEPQVASMDKASAAAAAGKPAAAKVVNATAAEAEVAALLSPKLAAAALAAAAKAARRSGPLDEWSRERMASFAATSPTPDWREKVLWLTNVCGYPRCSDATARATALPDWRQRLAWLTAAPAAPAAPAAPAAPAAPAAQGRDGGGGHGCEVGDGTTAASAHDDVRGVGGVCGHEGAGGASGGGGGVSSGGANGGGGFPLEQDAIREAAMGGRAEALEWILGEGGVSLRPSSSMKLCAFTARAGHTGALQVLMAHGHVMDEIMLSYAARRGHLQTVQWLSQVLESPPHRIYRYRSLDDRGHMADAVHSGNLQLLQWLADAGARAAHAAAQERQREALQHRHRLPELKQAQEQGQEGEEAAAAGGGQQQGAGSGSSSSSGAGVGGGGGCYSLAGEESIMAAACGSASCGVEVLEWLAARGCPLSAGCWAAAAGGGCSEDKLEWMAAAGCPLPPRTQKARKGGGGGGRGVAAAGAAAAPDASDLLVRAATSSDPVTLRFLVGRLGLGWSMDGHELAAVMDAWPASRTNAATLAAMAELGCVLRPAVLRRSLAALRQWLTQCGETEEGGPVAAWLQQRLQEAEADVAAARGRRWWRRRCGGGSVALRCVGAAAAAVAAVAGLGVVVGRGRRRAGGERQGRPGGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T081</accession>
    <name>A0A835T081_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Multiple inositol polyphosphate phosphatase 1</fullName>
            <ecNumber evidence="4">3.1.3.62</ecNumber>
            <ecNumber evidence="3">3.1.3.80</ecNumber>
        </recommendedName>
        <alternativeName>
            <fullName evidence="9">2,3-bisphosphoglycerate 3-phosphatase</fullName>
        </alternativeName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_011475</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="13">
            <text>(2R)-2,3-bisphosphoglycerate + H2O = (2R)-2-phosphoglycerate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:27381"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:58248"/>
            <dbReference type="ChEBI" id="CHEBI:58289"/>
            <dbReference type="EC" id="3.1.3.80"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="13">
            <dbReference type="Rhea" id="RHEA:27382"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>1D-myo-inositol 1,2,4,5,6-pentakisphosphate + H2O = 1D-myo-inositol 1,2,5,6-tetrakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77115"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="11">
            <dbReference type="Rhea" id="RHEA:77116"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>1D-myo-inositol 1,2,5,6-tetrakisphosphate + H2O = 1D-myo-inositol 1,2,6-trisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:77119"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:195535"/>
            <dbReference type="ChEBI" id="CHEBI:195537"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="10">
            <dbReference type="Rhea" id="RHEA:77120"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>1D-myo-inositol hexakisphosphate + H2O = 1D-myo-inositol 1,2,4,5,6-pentakisphosphate + phosphate</text>
            <dbReference type="Rhea" id="RHEA:16989"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:57798"/>
            <dbReference type="ChEBI" id="CHEBI:58130"/>
            <dbReference type="EC" id="3.1.3.62"/>
        </reaction>
        <physiologicalReaction direction="left-to-right" evidence="12">
            <dbReference type="Rhea" id="RHEA:16990"/>
        </physiologicalReaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Membrane</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the histidine acid phosphatase family. MINPP1 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.3.62" evidence="4"/>
    <dbReference type="EC" id="3.1.3.80" evidence="3"/>
    <dbReference type="EMBL" id="JAEHOD010000049">
        <property type="protein sequence ID" value="KAG2436537.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T081"/>
    <dbReference type="OrthoDB" id="6509975at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003993">
        <property type="term" value="F:acid phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0034417">
        <property type="term" value="F:bisphosphoglycerate 3-phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0052745">
        <property type="term" value="F:inositol phosphate phosphatase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1240">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000560">
        <property type="entry name" value="His_Pase_clade-2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029033">
        <property type="entry name" value="His_PPase_superfam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963:SF8">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR20963">
        <property type="entry name" value="MULTIPLE INOSITOL POLYPHOSPHATE PHOSPHATASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00328">
        <property type="entry name" value="His_Phos_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53254">
        <property type="entry name" value="Phosphoglycerate mutase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="8" id="KW-0472">Membrane</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0732">Signal</keyword>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="163"/>
            <end position="226"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="495"/>
            <end position="534"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="14">
        <location>
            <begin position="648"/>
            <end position="695"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="14">
        <location>
            <begin position="173"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="14">
        <location>
            <begin position="675"/>
            <end position="688"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004370"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008422"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012976"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00013040"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00018097"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022729"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00031642"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00043668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00043671"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00043691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00043832"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG2436537.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="695" mass="73684" checksum="591B8E9CB8E579FD" modified="2021-09-29" version="1">MALAVMLSRGAGVFDVRRHLGTKTRYAYRLAVPGAPSVYKHPDPEGYEPTHLWLMARHGTRWPTSDRMLQINSLEALFRDARNTGAHPWLANWTAPFPDVGFLGGELHPIGADELWGLAYRLRKRFPRLSGLEYLPKRFPVVSTQVARTAASASAFTTGFFPEVGPADDPADDSPSVNPSAPASSSSSSLTAAATAAAAATTGQGKAGQQQEQQQQQQQQQGPRVAVMEVDAAGRPRRSALRSVDAAAGVPGLLSAAELDATLRELPARKRPQAVAMSMAPKAADPLLRFFDVCPAYAQHDEYTEKWMGGWMQGNWSALVPALEQRLGLARDMDPCEVEALWQLCLLEAGLEGVGDRACSLFTPQEAMQLEWVDDIHLLETQAWGADINYQIAAPLLRDAALSLKAAAAASGAPGTGAPAARLLFAHCETLIPLATLMGLFRPPAPQPPDASPAAVDAAVSAAAAQRHLQQVDTLEDLHMIVSDLHRLNDQDALRARSKARSKGGAVGSEDSHSCYPGRPVDPDQLPPPEGWYPMLPNDDSRLFKGARLAPYAANMALVLYRRRDGAAAAASSPRHLVRLLYNEQVLPIPGCGSGSGLDCDLDEFLERMEGKMDADTLDRLCGPDSPPAKAGLRGDGGASLMFDRKRVPSKSLQHRPGGFVRGGVDGAGADAGAAAGGSGEGAGGKAGGDATPAS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T187</accession>
    <name>A0A835T187_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_011351</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000047">
        <property type="protein sequence ID" value="KAG2437092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T187"/>
    <dbReference type="OrthoDB" id="544490at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032427597" evidence="2">
        <location>
            <begin position="45"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="51"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="58"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="144"/>
            <end position="157"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="158"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="208"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2437092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="208" mass="20870" checksum="E0C12FFD33AB6D63" modified="2021-09-29" version="1">MHHAAGGCGRRGHRSSNRTSLLAAVLLGAAVLMAVHVGPLGASAQNNQVAFGQNPFGNNNQNNNNQNNNNPNNPNNQNSPPPSPSAASPPSPSPSSPPSPAAMPSPPSPASPSPPTPASPSPPTPASPSQQNNATSPPLAANSPPIPRQPPSSPSPSPNNNKNKPPQFNKGFSSTFSSQGFSSPSFSQASVAQAAFTPASNPQAVPSP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T196</accession>
    <name>A0A835T196_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">TATA box binding protein associated factor (TAF) histone-like fold domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_011363</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the TAF6 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000047">
        <property type="protein sequence ID" value="KAG2437107.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T196"/>
    <dbReference type="OrthoDB" id="361039at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000124">
        <property type="term" value="C:SAGA complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046695">
        <property type="term" value="C:SLIK (SAGA-like) complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005669">
        <property type="term" value="C:transcription factor TFIID complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046982">
        <property type="term" value="F:protein heterodimerization activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016251">
        <property type="term" value="F:RNA polymerase II general transcription initiation factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003713">
        <property type="term" value="F:transcription coactivator activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051123">
        <property type="term" value="P:RNA polymerase II preinitiation complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd22931">
        <property type="entry name" value="HFD_TAF6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="CDD" id="cd08050">
        <property type="entry name" value="TAF6C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.20.10">
        <property type="entry name" value="Histone, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.770">
        <property type="entry name" value="TAF6, C-terminal HEAT repeat domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009072">
        <property type="entry name" value="Histone-fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR037796">
        <property type="entry name" value="TAF6"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011442">
        <property type="entry name" value="TAF6_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR046344">
        <property type="entry name" value="TAF6_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004823">
        <property type="entry name" value="TAF_TATA-bd_Histone-like_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10221:SF9">
        <property type="entry name" value="TRANSCRIPTION INITIATION FACTOR TFIID SUBUNIT 6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF02969">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07571">
        <property type="entry name" value="TAF6_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00803">
        <property type="entry name" value="TAF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47113">
        <property type="entry name" value="Histone-fold"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0539">Nucleus</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0804">Transcription</keyword>
    <keyword evidence="3" id="KW-0805">Transcription regulation</keyword>
    <feature type="domain" description="TATA box binding protein associated factor (TAF) histone-like fold" evidence="7">
        <location>
            <begin position="5"/>
            <end position="71"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="182"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="526"/>
            <end position="550"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="684"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="189"/>
            <end position="211"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00007688"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023015"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023163"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="SMART" id="SM00803"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2437107.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="809" mass="81825" checksum="52D6DE40A13F2FF5" modified="2021-09-29" version="1">MSNPNFITPGSIRAIALSVDVTYLTEEAAKALAPDVEYRLREVIQDALKFARHSKRTKLTTQDINDALRLRNIEPLYGFLNNNDPAKFVRATGAPDLYFVRDDTVPLEQITCAPLPKAPAATTVMPHWLFINGVQPQTEENAAVDPRPAPKRQRLAAGAAAAGAGAGAGAAAVAGQADAVAGQKRKPGQDGADAAGGAAAAAGGAPVGQPGERVAMPVAHILSDEMQRLLQQIKATLGNPSPATLDAGSDERGEGGLWGCVLELDAAERGAGANGSGLLLTPMQRAVLTTVQRDPGMQQLLPYLTKHVGDEVAGGLRQLPRLHMVLRLVQALMLNPAVSLEPYLHSLMPPLLTCLMAKSLGNGPTCDHWALRDAAAAVVARICGRFGEPYYSLQVKVSKQLLRALLDGSKPLPTHYGAVAGLAALGPATVRLLLLPQLEPYLTKLQPSLPGGGLAGAAAAVAGGSVGAPAPGAGKEGVRQFEATRVYGALLQAAGSAMYDKLMAVAADSLPQHLFRTAGRVRRSLAPKQEAEAAAAAATPTTSPGVKQEPAAAGAAPGVAAPAAAAVVAAPPPVANPAIPEVVAVPAPAPDPTMEATWQRLQSDPKATQVFQVITANPGSKQSLSLLESLQQLTNRADGRANSGQAILYQLGKLGIGPPSAAKQYRASVAAAAAAAAAAAKGQPVANGLQSPPPAGAGGAGSGMSVTPPGSALRTPGSNIAAAGGQAHLGKGGRSSGAAAAAAAGGSGAGAAGGAGSSEPASRSVRAVLAESWREDADLGEVVGALTTLFGPAFLTRLPQPPQLPIMTL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T1Y7</accession>
    <name>A0A835T1Y7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013054</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000068">
        <property type="protein sequence ID" value="KAG2432334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552169at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="190"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="198"/>
            <end position="217"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="238"/>
            <end position="303"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="319"/>
            <end position="447"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="496"/>
            <end position="540"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1032"/>
            <end position="1076"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1513"/>
            <end position="1537"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="155"/>
            <end position="182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="254"/>
            <end position="264"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="326"/>
            <end position="345"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="347"/>
            <end position="370"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="417"/>
            <end position="430"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2432334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1537" mass="149510" checksum="7D5B11E287DFD159" modified="2021-09-29" version="1">MQNPVIDPTCDEGQDDCVERDAMVAYVEKHRCSPLTGKPLNIQQLKPNRPLKSIIWAQYWSIEIARAEKRNRDGAALSAALLPLQPLCAGAGGFTSAAGPAPIAAASVVAAAATADAAAESGRAPTAAPPAPAAAPPVQGAPEPVPFTPTANPVPAADPTAQQAGAAVTTTTTTPAAGSGSAPPAPATAPLPAVEGAAAVNASSSGGGEPSNTATALPADSQAVGPAVAQAAAATATGGAPVSMTGRKGCQSEAVAGAGPAAAVTRPEKSSRRPRPGYTPVRDTRPFPLQPRCGPQRVDQMSDERTGWEQLARVIQGGSASTTGPRLQAAAAQLRAALTQRQSPRGPRPRQRHRQPRPRPHQHQHQHQHQHQPDITTRSPSRLQAPPPRQRRQQHRPSCTQCSCRCRRRRRPGSRPPGGQQTGLLPLLAPLSPPPQPEARPHQEPGPRALLPAPLCRCLVRGPPALLVPLPLIEVLLAVAVPAAVLLVLLTGGSSRLRGGPSAPPAGGGGSGALGAATTGHGHAGNGGAREEHEDAAEAVEEVGAEALAAGAGGAAGAIAVASGVEVDVAAAAAWGGATAAGATAAPAQEAAAPVAASGTMSAGRRASVGAAAAAGAGVRAAGGSGDAPTAAAGTPLGLGAAAGAAEPLRAGPQGAGSSGQSGAVGGAAAVAGVPTRQLSPTKAVARSMADLQARLKAAAAHVRGAGAAGAGVGPTASVARRFDIDLAGARLEVPAPSAPGTELSSPPPALHITAPHVTLRNGTLLLPPGGRLLVEAAGVVFEDLDVSGPGYQPPSRDQEAGLVEVAGAGCSIRMERCKVTMSSWPEVAGGAAGGGDSGGGGSAGAGGSVGGGGGSGAGGGSAAGSASKGARASKAQGARAAAAAAAQHAPARLPPPVPGSRAECSCVLLCRGASAELHHCQFLYAGRDGLLGSGAGVRVAAAECLGIACASSGFGVTEAAHMDARRCLAQANGFFGFCSEDAASHMDVGAGCIAHGNGVGFGAICGGYMQAGTRRLPQAAAAATITTTAANAGNGEAGPSNAAAGGMATPTTTTTTTTTTTTTTTTNTTSSSAAAEAAAKSAARLAEAAARALDSPAAPLGGNSLHGDTKRWRVLGAALARQGACLALANREQGFGACKRGSRLVAGDGCVALRNGEGFAVLEGGALQAGGGCLALGSTSEVGGFVASGRESRLTVGDACRAEDGTRGAGFAALGGGRMQLGASCRAARNERRGFEAAGSGSQLTAGPNAQAHRNRNYGFASEGRGCVVLLGPGAVSSGNACAGFAAQGAGARLHVGAGGRAEGNQKDGFLALQGGGLAAAAGCVAAGNGQNGFRAEDAGSALAAGERCRAEQNGMAGFLCMSGAQLTTGDDCVAAGNKQEGYSAAGAKLKTGAGCRAVANESDGFAVFRQEGHQADTDVGLLDASAGGCEAEGNGGAGFCCEDGGCKLVAGPGCAAHSNRGPAGFLARDGGAVQVAEGCVSRGNAGWGYLATGKRATLQLGGGCKAAASEAPAGSGREGLNRAGAASAEHGGKLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T6F0</accession>
    <name>A0A835T6F0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">EF-hand domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_010555</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000040">
        <property type="protein sequence ID" value="KAG2439674.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T6F0"/>
    <dbReference type="OrthoDB" id="534781at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005509">
        <property type="term" value="F:calcium ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00051">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.238.10">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011992">
        <property type="entry name" value="EF-hand-dom_pair"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018247">
        <property type="entry name" value="EF_Hand_1_Ca_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002048">
        <property type="entry name" value="EF_hand_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13499">
        <property type="entry name" value="EF-hand_7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00054">
        <property type="entry name" value="EFh"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47473">
        <property type="entry name" value="EF-hand"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00018">
        <property type="entry name" value="EF_HAND_1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50222">
        <property type="entry name" value="EF_HAND_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0106">Calcium</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="190"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="domain" description="EF-hand" evidence="3">
        <location>
            <begin position="231"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="27"/>
            <end position="153"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="27"/>
            <end position="48"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="55"/>
            <end position="95"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="106"/>
            <end position="125"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50222"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2439674.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="269" mass="28168" checksum="D32FFB9738DBC82A" modified="2021-09-29" version="1">MGCSDSSLKQRAEEQFFEEQRKLRQATLQAATSTRSPDVALTEQQQQHAAAPSRAASHMSHVSHVSHASHVSHVSHASRGSRLPSRAASLAAAGLTQRPDGTLTLAGADGEAGAAAGKGPPSAAASRKAFQPLPGQADGGGQGEDEADEKPAARVLSKVTSGVLSGSLNVGNLFRAALEDTCELALTAETLPRIVEVILTALDKDANGTIEVADLKKFIQTVCREAELQVPPDEQVVAVFRELDIDGDGSISRAELAAVMFRWFIVGVC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T8J1</accession>
    <name>A0A835T8J1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">Dienelactone hydrolase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012654</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000062">
        <property type="protein sequence ID" value="KAG2433536.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T8J1"/>
    <dbReference type="OrthoDB" id="17560at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002925">
        <property type="entry name" value="Dienelactn_hydro"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051049">
        <property type="entry name" value="Dienelactone_hydrolase-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46623:SF7">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46623">
        <property type="entry name" value="CARBOXYMETHYLENEBUTENOLIDASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01738">
        <property type="entry name" value="DLH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dienelactone hydrolase" evidence="1">
        <location>
            <begin position="71"/>
            <end position="276"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF01738"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2433536.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="289" mass="30558" checksum="7B18488A23D8F619" modified="2021-09-29" version="1">MSRRARLPAALPEFGPAVAAAALVLGLPASVLIDEALDTASPRVNSIANENAKGVRMFVARPPAPAGGSGAPTKRPAVILIHQILGLQRREADLAAALAAQEDVVAVAPDCFQGQSTLWPFRAITLGFRYALRDGASWGVESVHEAVRWLKAQPDVDPDRIIVAGFCYGGGAAVRYAAAYPGEAAAVTIFYGRPLLEASEVAKLGRTPVLGLYGTKDAQFPASMLEKFKADLTASGVPHRLEMFEGEGHAFIKEAKSVEQGGAAGRAWELFRAFIRDVAAGRTLSVEPM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835T8K6</accession>
    <name>A0A835T8K6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">GATA-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_006580</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the type IV zinc-finger family. Class A subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000041">
        <property type="protein sequence ID" value="KAG2439052.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835T8K6"/>
    <dbReference type="OrthoDB" id="2162994at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006355">
        <property type="term" value="P:regulation of DNA-templated transcription"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00202">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.50.10">
        <property type="entry name" value="Erythroid Transcription Factor GATA-1, subunit A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051140">
        <property type="entry name" value="GATA_TF"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000679">
        <property type="entry name" value="Znf_GATA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013088">
        <property type="entry name" value="Znf_NHR/GATA"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45658">
        <property type="entry name" value="GATA TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00320">
        <property type="entry name" value="GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00401">
        <property type="entry name" value="ZnF_GATA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57716">
        <property type="entry name" value="Glucocorticoid receptor-like (DNA-binding domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00344">
        <property type="entry name" value="GATA_ZN_FINGER_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50114">
        <property type="entry name" value="GATA_ZN_FINGER_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0862">Zinc</keyword>
    <keyword evidence="3 5" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="GATA-type" evidence="7">
        <location>
            <begin position="861"/>
            <end position="919"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="1"/>
            <end position="53"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="504"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="583"/>
            <end position="651"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="721"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="842"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="912"/>
            <end position="946"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="989"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="6">
        <location>
            <begin position="10"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="6">
        <location>
            <begin position="37"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="504"/>
            <end position="562"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="6">
        <location>
            <begin position="583"/>
            <end position="593"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="6">
        <location>
            <begin position="723"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="756"/>
            <end position="777"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="784"/>
            <end position="794"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="914"/>
            <end position="930"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00094"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="PROSITE" id="PS50114"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2439052.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1194" mass="112884" checksum="C360EF3A0912849F" modified="2021-09-29" version="1">MVLAVHDGNGPTTTNDGSQRSQPETSQEDPITTKVALNHEEQDDAKSGSGANLGLPMPGAGLASGGMGGTAAGAMMSASLSPMAAAFSAMNMGGMGGMGGAANPMAQAMQAAMAGGMNPMAQMMAAGGMGGMGGMGGMGGMGPQAAMAQAMQAMGAGGMGGMGGMGGMQYNPAAYMQQMQQMMGPFAAMGMGGMPGMMGAAGGPGGSAAGNGAGAAAASGGAGASGAGNGSNGGAAAAAGSPAGNGAASGGAGAAAAGGGAGGTASGGSAGPGDVVTGMPLADIAQQWQMAQQQQQQAMMAYWWQMWMMMSMMGYGGMGGMGGMNPMAAAMAGGAGGAGGADPASQMQAMMASMMGGGMGGPMGTMGGMGNPAQYQAAMQAMMMQMAGGMGGMGGMGGAANPMAAMMAAMGGGAGGAGGGAGSAGGNPMAAQWMQQAQAMQAAMAQAMGGAGGAGAAGGMMGSMGGMGPMGGMMGGMGGMPGMMGGMDPAAMAAAMGGASPAAAAQQQAQQAQAQQAQAHQHAAHQHQQQQHHQQQQQHHQHQQQQQQQVAVQQAAHYGHAGSTTPASATMGPMAVAMGFKGYHHQHQHHHQHQPQQQHTHTHTHHHGNGAAAAAPGSSPPHHHGAADALGGASGGVEPMDAAGGGMGGGTSAAAAAAAAASVLEPPDDVDMVGVAASMGLTPHDMMGTGPMHGMLHGMHVPPGMGPMGPMGMLMLPANSDEAYGDEEEAGSEVEDGDDSDAHAAFGASQQHMSGSHAQPHQQSQQPALAQHNGFGHQPHHQHQAAAAFGGPQGVPQANPQLAAAAAAVLSAAAASAKRSLDQQGGAGNGFLARGGSSAGLGVGGLSGSNSNDSKRGRRATKEQKVCKNCGTKSTPFWRKDKNDGRPLCNACGLYFSKNDAPRPKILWKQDEQNAAAAREGAGGAAAPANGGAGGSGNGAAPPPAPANPLLADNAAAAALATVMARGGLTPAAAISAIAAAAANNANNAKAGGTSPPGSAGGAAAAPGSAPAAVPGGAGVLPGAPAGALAAPVAPGAPARPPMPPNITMMAQMQVAMAAMAAAAAAKNGAAAGAAPAAGGVPGAPGARPPMALAGNPAVATLAAAAAALAQARAGAAAMPGATGAPGAAGLPAALAAAAAANQTAALLAAGAPGAGSPPPPLPPAGGSPVVGGMEGGVVEVLPAMLPEIKAEAE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TDB8</accession>
    <name>A0A835TDB8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">DUS-like FMN-binding domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="8" type="ORF">HYH02_009400</name>
    </gene>
    <organism evidence="8 9">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="8" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="8">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="8">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443334.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TDB8"/>
    <dbReference type="OrthoDB" id="10262250at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017150">
        <property type="term" value="F:tRNA dihydrouridine synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052582">
        <property type="entry name" value="tRNA-DUS-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45936:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(20) SYNTHASE [NAD(P)+]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="3" id="KW-0288">FMN</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="9" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="7">
        <location>
            <begin position="9"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="6">
        <location>
            <begin position="341"/>
            <end position="422"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="341"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="6">
        <location>
            <begin position="372"/>
            <end position="385"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="7">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="EMBL" id="KAG2443334.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="422" mass="45081" checksum="8BC9E0A8F02E2715" modified="2021-09-29" version="1">MDYRDKLVLAPMVRVGMQPMRLLAASYGADIVYSEELVAQRVIASSRVVNKSLQSIDFLDRGGEHGRVMFRTTADEKPRLVFQLGAADAVMALQAAQVVAGDVAEVGLNMGCPKAFSLQGGMGAALLRKPEIAEDIMKTLHRNLSIPVSCKIRLLDTDQDTVELARRLAACGINALAVHGRTTQQRPRDPAHWAPIKLVVEALAPGCVPVVANGDVFSWEDAQRVKRETGCAAAMIARAAMWNASVFRPQGFLPLDEVQREFVRLALKWENALPNTKYCLKEMADAPPSFQGRRGGVRALVGHEANTAVTRAKDEASLCALLGLSSTAPYEDLGEGASGAVAASSGKVKAPKQPKAPRPPRHAKQRENGQQPSNGSSAPEEASGAANGGEGLKRKRDGADEGGEAQPDGQVQRQEEADAQVA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TGF9</accession>
    <name>A0A835TGF9_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Phosphodiesterase</fullName>
            <ecNumber evidence="6">3.1.4.-</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="10" type="ORF">HYH02_009366</name>
    </gene>
    <organism evidence="10 11">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="10" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="10">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="6">
            <name>a divalent metal cation</name>
            <dbReference type="ChEBI" id="CHEBI:60240"/>
        </cofactor>
        <text evidence="6">Binds 2 divalent metal cations per subunit. Site 1 may preferentially bind zinc ions, while site 2 has a preference for magnesium and/or manganese ions.</text>
    </comment>
    <comment type="similarity">
        <text evidence="6">Belongs to the cyclic nucleotide phosphodiesterase family.</text>
    </comment>
    <comment type="caution">
        <text evidence="10">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="3.1.4.-" evidence="6"/>
    <dbReference type="EMBL" id="JAEHOD010000031">
        <property type="protein sequence ID" value="KAG2443297.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="541199at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004114">
        <property type="term" value="F:3',5'-cyclic-nucleotide phosphodiesterase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0007165">
        <property type="term" value="P:signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00077">
        <property type="entry name" value="HDc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1300.10">
        <property type="entry name" value="3'5'-cyclic nucleotide phosphodiesterase, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003607">
        <property type="entry name" value="HD/PDEase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023088">
        <property type="entry name" value="PDEase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002073">
        <property type="entry name" value="PDEase_catalytic_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036971">
        <property type="entry name" value="PDEase_catalytic_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023174">
        <property type="entry name" value="PDEase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11347">
        <property type="entry name" value="CYCLIC NUCLEOTIDE PHOSPHODIESTERASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00233">
        <property type="entry name" value="PDEase_I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00387">
        <property type="entry name" value="PDIESTERASE1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF109604">
        <property type="entry name" value="HD-domain/PDEase-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00126">
        <property type="entry name" value="PDEASE_I_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51845">
        <property type="entry name" value="PDEASE_I_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="2 6" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="1 5 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="11" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="PDEase" evidence="9">
        <location>
            <begin position="1759"/>
            <end position="2125"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="246"/>
            <end position="268"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="299"/>
            <end position="341"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1494"/>
            <end position="1517"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1543"/>
            <end position="1588"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="1978"/>
            <end position="1999"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="1352"/>
            <end position="1407"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="8">
        <location>
            <begin position="247"/>
            <end position="262"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="299"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="327"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1501"/>
            <end position="1514"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1552"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="1571"/>
            <end position="1580"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="1989"/>
            <end position="1999"/>
        </location>
    </feature>
    <feature type="active site" description="Proton donor" evidence="3">
        <location>
            <position position="1840"/>
        </location>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <begin position="1840"/>
            <end position="1844"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1844"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1881"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="1882"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1882"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="1882"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>2</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="2031"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="5">
        <location>
            <position position="2031"/>
        </location>
        <ligand>
            <name>Zn(2+)</name>
            <dbReference type="ChEBI" id="CHEBI:29105"/>
            <label>1</label>
        </ligand>
    </feature>
    <feature type="binding site" evidence="4">
        <location>
            <position position="2082"/>
        </location>
        <ligand>
            <name>AMP</name>
            <dbReference type="ChEBI" id="CHEBI:456215"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PIRSR" id="PIRSR623088-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="RuleBase" id="RU363067"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="PROSITE" id="PS51845"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="EMBL" id="KAG2443297.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2145" mass="221809" checksum="3ACF44F4BCA2BD71" modified="2021-09-29" version="1">MEADANRPLEAGTRHHLLHLTSTAASYCEMPAGGGGGGASCDLGRHSSSGRMLVDLDEAVAAAAAAAAAAASILAGSGRAQAAAGDAGGSAGGAGGCCGASYEAAGAAEADAGSGSGRGLISGTTEGDATTALGAPTTAVNSGVAGGCSAADYASLMESFMALKASYDVLLQQQDAMMDAEAAMEALSSPARPPVVLASGPSAMAAPAAAVAQAQTPAPQQTAMLKPQQLQQVVLQQQEAIQCRPISPTSSRRASLMSSAPTVVQGHAHRGMARRGSITGLMCLGLGAGGEGATAALSANSRVGSSQDDSSDQATQDAVGNCPMDGSGSGGDGGGDGASSVRGGSVVDAASIVLMDTGPSGAQCASPMSLLHKGLSSMASSGGVGELERLAAHARALKATCDVMQLQRDRAVHAATAQKATFDRALAAAQLEAEVVADSAAATKAQFDKFVLDKAEEKAAFDAVLEQTAAAAAQQKAIADKALVDFGELQANAVADKAVHDKALFDFQATAAADKAVHDKAMFDMQATAASTKAQFDKFVLDKAEEKAAFDAVLEHAEATAAQQKAIADKALVDYGELQATATANKAQFDKFVLDKAEEKAAFDAALEHAEATAAQQKAIADKALVDFGELQATAAADKAVHDKALFDMQATAASTKAQFDKFVLDKAEEKAAFDAALEHAEATAAQQKAIADKALVDFGELQATAAADKAVHDKALFDMQATAASTKAQFDKFVLDKAEEKAAFDAVLEHAEATAAQQKAIADKALVDFGELQATAASTKAQFDKFVLDKAEEKAAFDAVLEETAAQASQQKAIADKALVDFGELQATAAADKAVHDKALHDVQANAASTKAQFDKFVLDKAEEKAAFDAVLEHAEATAAQQKAIADKALVDYGELQATAASTKAQFDKFVLDKAEEKAAFDAVLEHAEATAAQQKAIADKALVDYGELQANAVADKAVHDKALFDFQATAAADKAVHDKALFDMQATAASTKAQFDKFVLDKAEEKAAFDAVLEETAAQASQQKAIADKALVDFGELQATAAADKAVHDKALHDVQANAASTKAQFDKFVLDKAEEKAAFDAVLEQTAAQASQQKAIADKALVDFGELQANAAADKAVHDKALFDVQATAASTKAQFDKFVLDKAEEKAAFDVALEHAEATAAQQKAIADKALVDYGELQENAASTKAQFDKFVLDKAEEKAAFDHVLEQTAAQASQQKAIADKALVDYGELQANAAADKAEHDKALYDVQATAASTKAQFDKFVLDKAEEKAAFDHVLEHAEATAAQQKAIADKALVDMSELQVVVAADKAVHAKALLDVQQTADATKAQFDKLVADTAEEKAAFDVALVRAAEEAAEHQRRADTMRAEAEAAAARHASERQCMDDLQAQNERLLKQQEVLQAELAMALRSYTPRTIIDAGTPADKILAMMTDLLDGSPPTIQDILFVQSAILEAHDVYKPVNLGKQLLGSSALDKDVGLSLLQQLGGQDEADEATRAANGSASGGAAHHGAPGGVAGGGAGAALTLRDFGTRDAAMGRAVSAPQQPAGLSGSLSGGSCSSSLHGEEAGAGGGGAAAGGPQSAPAVSWDTLESALTAIMALGGPLEDNNNISNNNNTPTAAESSAAASGCVSRAGGCADGFALVSGSGAGSGPLGMAAPGTPRATALAAAAALQDGGAGRALMRAVSSASRSMHARARVGTVSAGQLSLCAAGGATGGATGGGTGGGGGGLVLGTPPLERTNTAASLATTVTELCELDEFPEQPLYTEVERVLSTGVGSWQWDAFKLADASADHALSTLGYFLFHQSDLIRKFDLRPQQLAAFLRRVEDGYRPNPYHSKTHAADVLQSLHVLIHRGGLAPGYVDPLSLLACYLAAIIHDYEHGGLTNDYLINSGDELALRYNDRAPLENHHCAAAFLLLRRPEYAFMAHLPKADTDRLRKMVIELVLATDMKQHFAIMSHFTTVHRLTSATSVTPSLMSGERRRSSSNASSVNSLACSGSGVELDKILIPLDENERILSLQMALKCSDIGHVCASLPVHLRWVAALEEEFFRQGDMEKAHALPVSPLFDRAKPGITKSQVGFFDIVVIPLLSNFSRVFTNTKPLLTYTMRNYKYWSEAQKTEQQVAAAAAAQAAAAAASGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835THH2</accession>
    <name>A0A835THH2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_010319</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000038">
        <property type="protein sequence ID" value="KAG2440434.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835THH2"/>
    <dbReference type="OrthoDB" id="630895at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2440434.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="165" mass="16972" checksum="F0B971A4D18F9C5E" modified="2021-09-29" version="1">MALATSEVTWNSEETVEAVLERFAQAKSRVQLDRAEERLLLKVTPSPGGRSVSVKLSVACLAPALRCVQVVRVTTSGNVSEPLLAALFKHCDLSGVWKLRGAEGFGNFWCRCGPGAGRGGNGNGNGNGSGSGSRCCSSDSARLGARHSCRVAPTAAGVGAGRQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835TJL6</accession>
    <name>A0A835TJL6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">U-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_010729</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000042">
        <property type="protein sequence ID" value="KAG2438935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835TJL6"/>
    <dbReference type="OrthoDB" id="10064100at2759"/>
    <dbReference type="UniPathway" id="UPA00143"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004842">
        <property type="term" value="F:ubiquitin-protein transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016567">
        <property type="term" value="P:protein ubiquitination"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="CDD" id="cd16655">
        <property type="entry name" value="RING-Ubox_WDSUB1-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.40.10">
        <property type="entry name" value="Zinc/RING finger domain, C3HC4 (zinc finger)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003613">
        <property type="entry name" value="Ubox_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052085">
        <property type="entry name" value="WD-SAM-U-box"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013083">
        <property type="entry name" value="Znf_RING/FYVE/PHD"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46573:SF1">
        <property type="entry name" value="WD REPEAT, SAM AND U-BOX DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04564">
        <property type="entry name" value="U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00504">
        <property type="entry name" value="Ubox"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF57850">
        <property type="entry name" value="RING/U-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51698">
        <property type="entry name" value="U_BOX"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="U-box" evidence="2">
        <location>
            <begin position="259"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="77"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="296"/>
            <end position="329"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="343"/>
            <end position="362"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="94"/>
            <end position="112"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="304"/>
            <end position="313"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="343"/>
            <end position="355"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS51698"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2438935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="362" mass="37668" checksum="F9B6A7A4CE8BDEE5" modified="2021-09-29" version="1">MSNVVTEEKRAEWRQFGNNLLAQEFGTSRYAHKLSAVVNRAEEEAFKDWPSDQAAYEAALRRRLKKSKDGIRTMLHQAGPRPWTAGGARGADGGSTSSGAGSSRQGPPATAAGAGAVAAGAAAGAAAGAAAGAVAAGDAPALSGREKLLAEYWCLVGQLREHLTLLQRQLDKCQGSLCPKASRSRRILAEAHKRCTAEPGSAAAASYPITENTVKLMRAVLASLMPSANQAAGGAPAGAATAAAAPVIRAAAGVTEGAEPPPIFICPISQELMHDPVVAADGHTYERRLIEEWMRRGQQQGPAGAAGAGGGGPAPRSPMTNQPLPHTALVPNLALRSAIREWQEAQRRQRQERPQGARCPLP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VP32</accession>
    <name>A0A835VP32_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">Protein BCCIP homolog</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_015435</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the BCP1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000219">
        <property type="protein sequence ID" value="KAG2422485.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VP32"/>
    <dbReference type="OrthoDB" id="27543at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR025602">
        <property type="entry name" value="BCP1_family"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261">
        <property type="entry name" value="BRCA2 AND CDKN1A INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13261:SF0">
        <property type="entry name" value="BRCA2 AND CDKN1A-INTERACTING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13862">
        <property type="entry name" value="BCCIP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="267"/>
            <end position="326"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="395"/>
            <end position="468"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="30"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="89"/>
            <end position="99"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="270"/>
            <end position="284"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="402"/>
            <end position="450"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="451"/>
            <end position="468"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006781"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2422485.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="468" mass="48114" checksum="61E029C32EFE36BA" modified="2021-09-29" version="1">MPKRKADAALKKKGEEEAEDAAKKQTAGGGDEDDSEDDDDYEGEGGSEEGGSDDSDGDSDEGEGDEGEDEDESSGSGDSEDSFPSASSDEAESEDDEDGEAYKEIDCAFEFFDPQDRDFHGLRALLGTYLDGAAFDLSGLCECVIAQSAVGTVVKSAEDDDPFALLTAFNTARGAAAGATWLAELKAYLTTSCPEPALREKLEKAWSGPGTGLLVSERLINCPPQLAPPLLHFLMEEIEGAATDPAYPEAERSEFAFTRYLHFTRVYSDPQEEEGEEEDGEEGEGDKGAGPGPSGSMGPPPPKKPKTTAGGGAAAGAGASKGKQQQQPVIVYVRPEDEYLHQVCSWSYTFPVTSRPVAKGDLRPLRCVMCVEAGRVAEARAMMDLVVGNPMAGEEGPGAGGAAAAAPKQGQGKKQEAAAAGGRQAQGQGQGQEAAQAAGGNKGAAAAGPAGAKGKGKAAGGKAGGSGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VR48</accession>
    <name>A0A835VR48_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015154</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000122">
        <property type="protein sequence ID" value="KAG2424675.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VR48"/>
    <dbReference type="OrthoDB" id="514817at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.160.60">
        <property type="entry name" value="Classic Zinc Finger"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="81"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="356"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="398"/>
            <end position="417"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="530"/>
            <end position="666"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="289"/>
            <end position="322"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="374"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="400"/>
            <end position="412"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="540"/>
            <end position="572"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="582"/>
            <end position="613"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2424675.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="683" mass="68750" checksum="B056575B9151A81E" modified="2021-09-29" version="1">MEGLDAQEALQLDVVSKPAAAGDKRDPERFYCPYPGCNRSFAELWRLKVHYRAPPDIRGSGKERGHGTELTHCPKCGKTLKPGKHHVGCSGGKSAPRQTASKRNRTGADDADEAVPGSPHSKHVRGTDMDGDPHKSWQDFAHAHAGYAMGAPAMLAPLKPEHTEWPPTVPQGVFVGHGEVSWLPGQVNGFVPQLQPQRYQQPQFPPELAQYAAPGAHPHVYAQQVPFASIPGYPGQPGVATLQVTTESGQVLSIPANMAGMPPGMAGLSGTLVYHQQPPPPHDPASYLAQAQAQHAAAMHAVSAHAQQQQQQQQQQQQAGAPAVPPPVHDGMPPGAAAAAAAAAAAVAVGGSGAPGALQHDSGGRPGAPLPPHAGGGAGQGVADGGAAADAGAVPGGDAGAAAAAGSGAKPNGADEDNLGNVFDDVEEFTRDFGRIPSPPPLPPDFHTAATGGNGMLFNFSQFGQKLPRTQSHTRLDRSLSAVGLGHLDVGLDADVMYDHSDDGDLMQLLFGVPDELPTMATIHLHKWSNEEDEDDDAGEPGGEAGGAAGGGEAGAGAGGGAAGAGAGGAGSGEASAAAGRGSSGAGPGPGSEAGASGAGGGAAEGGAGGPGAGHQQPHQQTGGHDQRPLNGKMLHGHDAPLAAHPAPGGKALMNGGPGHSGDEHHRDHLLDAETFRLLQSCD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VRT0</accession>
    <name>A0A835VRT0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015320</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000142">
        <property type="protein sequence ID" value="KAG2423478.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VRT0"/>
    <dbReference type="OrthoDB" id="429813at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.300">
        <property type="entry name" value="P-loop containing nucleotide triphosphate hydrolases"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR027417">
        <property type="entry name" value="P-loop_NTPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052736">
        <property type="entry name" value="Stf3_sulfotransferase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36451:SF1">
        <property type="entry name" value="OMEGA-HYDROXY-BETA-DIHYDROMENAQUINONE-9 SULFOTRANSFERASE STF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR36451">
        <property type="entry name" value="PAPS-DEPENDENT SULFOTRANSFERASE STF3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13469">
        <property type="entry name" value="Sulfotransfer_3"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52540">
        <property type="entry name" value="P-loop containing nucleoside triphosphate hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="225"/>
            <end position="246"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="263"/>
            <end position="333"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="404"/>
            <end position="424"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="263"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="297"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="301"/>
            <end position="318"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="319"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="411"/>
            <end position="424"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2423478.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="588" mass="63321" checksum="533E0BEBABDB18C8" modified="2021-09-29" version="1">MMPAEDGQGARPRGHGASARGAPARGELPPYSYEPLKHRWELKLNFMSGVTLGPWLSFLWTHWRDIDWGLFWHRVAFLTCMSVVNTLLSAFDWLLHSRAVAAQPLHPEPLFILGHPRSGTTHLHNLLSRDPAFAFANTFHAGFPSSFLALEPARGLLAGLLAPTRPMDRMALSWELPAEDEIAVNVLSGCRVSPYAALVLPRAWRAAGVAAGGAPGGGEAVEGGSRGAAGGGGGGAGAAGSSGRAGGGVVGLRDFLDWEWEWEEEVESEEGAAAEHQAQGEEEKQQQEQATRREAQRQRQRPLPAQQRSGGAAAAAGQDAGGGAGTGTGMGAEGHPVAAAAAAAAAAPSRQSPHQRRRAALRAAAFEEWLASFMWFMKKITYRHVRLQQQRTAAATAAAAAATAPGCSGAQPPPPAAAAQPPQPPMLLIKSPVHTARLGTWLRLFPRARFVYVHRHPLEVFQSAAHMANTYYPYTYLQAPDDATTNDFIMDQYELMYSSYASRRAAVPPGRLVELGFGELEADPLAALGRVYEAFGWSDRWPAVAPLFGDYSASLADFKKNQFTRLTPEAEAVVRRRWAPSFAEFGYQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VS75</accession>
    <name>A0A835VS75_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015300</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000140">
        <property type="protein sequence ID" value="KAG2423599.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VS75"/>
    <dbReference type="OrthoDB" id="548027at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="47"/>
            <end position="324"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="478"/>
            <end position="517"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="70"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="71"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="82"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="150"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="230"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="241"/>
            <end position="267"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="290"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="301"/>
            <end position="311"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2423599.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="582" mass="59292" checksum="F5F05726E07A57FB" modified="2021-09-29" version="1">MQTFSIHNGYRQCIARTVRRTAWAGHRFVSRWGSTPSYIIDDSLPGPGPSSLAAAVAAPSATSNSSAGAGPSSGGRGGGASRRGIPRGQKQQQQQHRQQAASGAEGEGFPPPAPSTSILDVAARAHSPDSDTESDDPSPGSRRGSGRGTSGAAAARGRSGRQQQQQQQQQRDGGGAASSSSAASTTAPPGGRKFRSASAPTSAVVAGSGAAVAAAAAGAAVVAGAAGASTGRSNQNGSITNSSNNSNSSNSSNSSNSSNSSSSNSDRSGGHRSAGRGSGRQAANGYDNNNRNDTKARAHEEEEDDDDDDEAGAPPPSFLRLPDGRQLVPLRPDTAAAAAAGALSRALGVEGKAVVRFDGAAGGLKGLRVLTLAHAFMGAFGRGLSFVVDVRQSAPSASERPQAGDVSFGFRAMARSRPLEAHEAKLGAALREARFVLDLSINVRQAWDCKGDIDEEQAYDLADTFYAALAAQQADEDAEEAAAAGAAGGARSRRQQQQQPREGGGAGAGPDLPPPGVFVTADLAQGLTTFAALGLLQKRLREEGQNVVAEATMYRASASAPRLDGRDGWIFGLRLGRPGPYM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VSX5</accession>
    <name>A0A835VSX5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_015180</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000125">
        <property type="protein sequence ID" value="KAG2424319.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VSX5"/>
    <dbReference type="OrthoDB" id="10662515at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="342"/>
            <end position="361"/>
        </location>
    </feature>
    <feature type="non-terminal residue" evidence="2">
        <location>
            <position position="499"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2424319.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="499" mass="53414" checksum="FC6BF8121FCA22DC" modified="2021-09-29" version="1" fragment="single">MQRAAPSAAKAAAPAAPADAADAAEASALLLVLRVLGHGPIGEAMMGLGARGWAGARRSCRALHACVDDAGREAELTVDLAEALGVWPAGRLSRCSALTVRVMTGGGQEEGGQGMPLITTAPARQPGETEEELAHRQKEQRDMEAQIIDECKALLPDPQQLAPWLDTVAALGDKKAAVLASLVNPRLRMGNTGFDGMMVTDGVATSLQYTRTVPGVRARLHKTQRAKKVREACEEPPSECKHGDTTIADVINTAILQGLGMEEGCSMQTVAVLGWDPGRCVIATVVLVDLQGKTHTWRLTRGEFHNRSGIRTYTRKRVSRMGPDLIKKLCDLGSKTNIAAAGENTEEQEQDSGAEASDYSDLTTPAEAKLHSTALRASTSGEILQYAIQTADILPDWWRSALRRTERRCRLGVFSGKRCILDGFVAKVLREASAVLARDQQLEARKPLLQVAYGEAGMSMPASGRGELAVPTSGMFKALKRVCRATSIAAQKLPQVPRC</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VSX7</accession>
    <name>A0A835VSX7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_014445</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. STE Ser/Thr protein kinase family. MAP kinase kinase kinase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000096">
        <property type="protein sequence ID" value="KAG2428097.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VSX7"/>
    <dbReference type="OrthoDB" id="4062651at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004672">
        <property type="term" value="F:protein kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050538">
        <property type="entry name" value="MAP_kinase_kinase_kinase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016">
        <property type="entry name" value="MAP KINASE KINASE KINASE SSK2-RELATED-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48016:SF47">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="6">
        <location>
            <begin position="70"/>
            <end position="440"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006529"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2428097.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="440" mass="46165" checksum="71EC55F9EC08105B" modified="2021-09-29" version="1">MGANASSIDKQYRRINKLAPNAVWALDAVNAYARASPCEQALVRSAPSSDAREVLDELILRFKGDAASRVSAEQGGGRGVGGGVAPAPAVAATGVLPAAVSGGGASGASAAVSGATVSPALEDVLDLPNYYDRFVKLLARGNITRPREDVLAAIFRRHAYMLAVVPDSNKAVELYRAAELFPGASTEGHLLTQHGLKIDGPLFPAEGSINLLTAATNEGIPAVVKLLCQDAGGAEAEACRVLMEEKPEDVPLVPAKILPLQLGAEHTSSTGRAPGLYAAMVMPRYVSSLAAMVPLTPAAVLAGAERISKALEWIHGKGFTHMDVKAANIFVDADGRWWLGDFGSAVRAGLPVKSTTTWFAPSKLQGLPAQPQYDWHMLAVALVCEVNRTNWKDLLIEGGCTPAHKLTAAVTELHGRNDCKALAAYLDELLLRAGHVPAPT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VTX5</accession>
    <name>A0A835VTX5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_014183</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000088">
        <property type="protein sequence ID" value="KAG2429147.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VTX5"/>
    <dbReference type="OrthoDB" id="1885901at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0001730">
        <property type="term" value="F:2'-5'-oligoadenylate synthetase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003725">
        <property type="term" value="F:double-stranded RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1410.20">
        <property type="entry name" value="2'-5'-oligoadenylate synthetase 1, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.460.10">
        <property type="entry name" value="Beta Polymerase, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR043519">
        <property type="entry name" value="NT_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11258">
        <property type="entry name" value="2-5 OLIGOADENYLATE SYNTHETASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR11258:SF11">
        <property type="entry name" value="C2H2-TYPE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81301">
        <property type="entry name" value="Nucleotidyltransferase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50152">
        <property type="entry name" value="25A_SYNTH_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="49"/>
            <end position="83"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="522"/>
            <end position="532"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="533"/>
            <end position="545"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2429147.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="557" mass="59704" checksum="3E9750067F063D14" modified="2021-09-29" version="1">MRASLLAATTTAPVRPPLLLRRHQRGAAANSSSSLVAVTVSASATTAAGLARGTSSSSSSARCSSLGGSSSRPAGSSSYISTSTSRAQPVARAYTLQLHGFAEREGRYKKAPRRVEARAAQQAVFKRGQALLLEDPRVLKADLQSGRKQFAKGLNSVMQQFVKWAEEDSAAREAVDRVARTVQRVGTVKASRVIVAGSLGRGTDVTGAHDVDLLFFIHEWKNGIDLSTLAAWGDEAQMARVRREVKDALQRAQPSWRVEILNLAHYRNVLQVTLGGVKVDLLLLPDCAKGATLPQDAWALQQLQQLMRPAVFAHPDAAAYDQLRERATSPALNELLAAMPAEVKEVVRFVKGLYKLGLAPQEAERIRSFSLEVLVLAAHQQCQQTRWRRGLSANDYKLELFLDFLRRVVAAARERQVIMVDAGMWGYRREAGEQFAHCWKGGDGTPDAIRIIHPCDPTCNLERGRVHRGASDWTTLVEMAEELLELLLGGQRGTVPVVVKALARVQVSSSSGGSSSGGAGGSSSSSSDCSSNAGGGHGGGAGAADGGWDTLNRGVGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VUZ3</accession>
    <name>A0A835VUZ3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="10">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_014691</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000104">
        <property type="protein sequence ID" value="KAG2426838.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VUZ3"/>
    <dbReference type="OrthoDB" id="377346at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:000813">
        <property type="entry name" value="Aurora-like kinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR030616">
        <property type="entry name" value="Aur-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24350">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE IAL-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 7" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 7" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="10">
        <location>
            <begin position="205"/>
            <end position="470"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="1"/>
            <end position="39"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="61"/>
            <end position="114"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="543"/>
            <end position="570"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="599"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="9">
        <location>
            <begin position="960"/>
            <end position="989"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="9">
        <location>
            <begin position="82"/>
            <end position="93"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="9">
        <location>
            <begin position="96"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="543"/>
            <end position="557"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="9">
        <location>
            <begin position="599"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="active site" description="Proton acceptor" evidence="6">
        <location>
            <position position="329"/>
        </location>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="234"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="282"/>
            <end position="284"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <begin position="333"/>
            <end position="334"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="binding site" evidence="7">
        <location>
            <position position="347"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <feature type="cross-link" description="Glycyl lysine isopeptide (Lys-Gly) (interchain with G-Cter in SUMO2)" evidence="8">
        <location>
            <position position="331"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-2"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="PIRSR" id="PIRSR630616-3"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2426838.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="989" mass="101525" checksum="C41C3B15AA566EEF" modified="2021-09-29" version="1">MRRVLKKVFQKNERQDESDSTLDLNLPSDRSLGASSPLARGVNPAVEQLLFKSAAEAAGVGPTVKPPAVYQTHTGGPPSHLHQPQASQLQQHSPLKPHPPTGAAPPSPGALLPALASSSPAGAAMSAFPLAAQVVAAPGNMAVAPAAAGTPNAAVLYTAADAAAPSLPSPPRDHVAAKSYDSVTIAMGRHCPPALRREKWGVGDFDLRRLMYNGAISMVYHAVDKRSGITVALKLYKRIKLNEIERHQVAREIRLHSELCHDAIIALYAAWKDRAYVYLALEWAPGGDVYSYLKSQRGRLAEELAVPLILEPFMAGLAVIHDQGLIHRDIKPENMLLTNSFQVKIADFGLSIDSKQEIANTRLGTIDYLAPEILDCPVKQHPEDHKDRPDTGYTNKVDCWSVGVLAYELLVGQPPFAAPSAQETLRLIRTKKVEYPNWLSADAINFISSVLVRDPTLRPTIEELLQHPWIIKYSRREGAAGAGRGRARMLRRGTVDGGGVGMLVRSNTVGGVADLLPLTAQQQQQQQQQQQQMQAAQMQQQQQQQAAAASNNQQTQQYVPHPPGAAPPTTNAAAFQAQLAAAAANGQLLQPQYQQQQQQQQYQQQPQLQHAQTYGHGNALGGNHAAAAAAAYVQLQAQHQQMQLQQQLQAQQLQQQAFQQQQLQLQQQLATQHAQHHAAAVAAAAAHGGTGTGGGGGNNVMSVVMDDAEMDIGGGGGVPLYSVALPPPGAPAGSAAACPLTSSAPPGTMAPGTIGSATPALAAVAAAAADKGSAGSLLARKLKFWSSASSASSSSAAAAAATPVQVSMQQPTVHQLGPGSGGAVNAGSGGDAAAAAGLYSLSSPSSGRVGPLPPVAAPAPSAAAGLFARLTASKSKGSVTLAAAGAGGGGLPSSTSSGGASPTAAGVVGAVAMLAAPGSPASRLGSPARLGGGGGSASSKSAAMLAAAAAAAAGAGLGEPMGCSPMEGVEGSPRSGRGASFARNLGLAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VWB8</accession>
    <name>A0A835VWB8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">F5/8 type C domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013778</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000080">
        <property type="protein sequence ID" value="KAG2430300.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VWB8"/>
    <dbReference type="OrthoDB" id="531889at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.120.260">
        <property type="entry name" value="Galactose-binding domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.80">
        <property type="entry name" value="Glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017853">
        <property type="entry name" value="GH"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51445">
        <property type="entry name" value="(Trans)glycosidases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="270"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="359"/>
            <end position="390"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="275"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="359"/>
            <end position="373"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2430300.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1100" mass="113787" checksum="DB2AC10FAAF6A758" modified="2021-09-29" version="1">MWQSGACFPTGYLTRPGLNALLWACNATSAAPCTASSGSSGLAAATDSLTAGASASITFSATAAAASPYGGAWMRVPLTGAGAAGRSLSRVGLRGVFPAAPGLVRLYLELASGGVVGPLLAANGTSSYSWLAAAGTWDGVAAVVVNGTAPFSVQEVGAAAGACEETAVVDLGAERSVGLVRTRYWPSSALGSWLLAAPDTSPAAAAAAALLGSPLESLPPSWVVAVLDPSRLAALTLNLPAPVQARYIAVRHRVPPTDWAKVSVWDIQAWGPQASPSPPPSPSPPPPPSPDNWFPLAGSVKSFSLGGAVTVSSNPDPSALPCVADSNDNTQWQSDACYPTGYTSRPAMNPLLRLCTDASSRTAPAPPADTSSPGDGGGCTASTGSSGLPQATDTSVYTGAAIEADPAALAAGSPAAAFLFAALPPHPADAPEQPRLVRRVSAKVWWGSSGGGGAQVAVVLLFADGGRQEVGRLTPGVDDYAWHHITGSWTGVVAVSLESAARFQLTELALSAGPCVEWAAVDMGAVQPVGVLRFRYWSPDSAAADLHVSADGVAWTPIRTGLDPTQLSALEIYLPTVMQIRHLRLTHRVKEDGDWRKVYCWGLDAYDLFGRWGPPPPPRPQAASLRQLLGVNGIWGWGFNKFSRDLAKTGSGPALYSPVAARGRNYHAMRWDVRSPLNDPKYDTMAKSGTDVFWWLNWDNEYVGWKAAGLTVDASFQFLAEDFPPAAWGPDPAGAAYRLGAAFARHFGPRLAPPNVSLDSVEVGNEPWTGYNASFYSAILRGFSRGVKDTDPGLRVLPCALQAAEPLAEDPSNGNFVGARIGPDVAPRLDGLNLHVYSWFRDPEGVGGPPAGAVGAHRGVHPEHRGSSMNGLNNMLAWRDANMPGKPVWVTEWGWDAALPGEVCATSLCVSQHAQALYAVRGLALLARKGVAGAHWFFYANGDDCNTVFCRSGLRGSNATRFPVLPVYRSLLGLMQTAGSAAFLDVLAESPDVYAYLLGAPATAAATGGAAAATHVLVWRPVAAGEGPAEAEPSAAVTLTLPRAPTAAWAISGAGAVPVSQLGAVAVRAAAAPAPGAGADPSGPADWTLTISAVPLLLKF</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VZD8</accession>
    <name>A0A835VZD8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">ELMO domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_013397</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000074">
        <property type="protein sequence ID" value="KAG2431264.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VZD8"/>
    <dbReference type="OrthoDB" id="67155at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006816">
        <property type="entry name" value="ELMO_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050868">
        <property type="entry name" value="ELMO_domain-containing"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771:SF56">
        <property type="entry name" value="CED-12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12771">
        <property type="entry name" value="ENGULFMENT AND CELL MOTILITY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04727">
        <property type="entry name" value="ELMO_CED12"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51335">
        <property type="entry name" value="ELMO"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="ELMO" evidence="1">
        <location>
            <begin position="123"/>
            <end position="307"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="PROSITE" id="PS51335"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2431264.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="333" mass="36740" checksum="743FC74F7C0C7041" modified="2021-09-29" version="1">MASMRRRKQAKDEQLTASLLDDYDALEAEDVGPAVQQQQQPARAKAPGLSSSAIILHPGEFNLQAFVASILAWWQRMFGQIFSYATHLWPVPQRGPELSLLQAERLQQLRDKVAERFDIASPSHQDSLRRLWNLAFSGEPCTALKTPRWKDMGWQGEDPATDFRGAGLYGLDNLIYLAEVHPDTFRRLMDKSEGTRATWEYPFAVAGLNLTWALSELLELHAPTGAAAAAAAASSSSDSASGQGPRPPRGATGRAFLKLLAESDVAFEELYCAAYCLLDATWLEMRASYMEFNAVMKRVKGEVERALASRPTDMAQLRQRLLAAVPGAAAGWD</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VZF4</accession>
    <name>A0A835VZF4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="2">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="13" type="ORF">HYH02_013452</name>
    </gene>
    <organism evidence="13 14">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="13" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="13">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="8">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="similarity">
        <text evidence="1">Belongs to the protein kinase superfamily. NEK Ser/Thr protein kinase family. NIMA subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="13">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000074">
        <property type="protein sequence ID" value="KAG2431324.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VZF4"/>
    <dbReference type="OrthoDB" id="248923at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="CDD" id="cd08530">
        <property type="entry name" value="STKc_CNK2-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000097">
        <property type="entry name" value="Probable serine/threonine-protein kinase nek1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051131">
        <property type="entry name" value="NEK_Ser/Thr_kinase_NIMA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899">
        <property type="entry name" value="CAMK FAMILY PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44899:SF6">
        <property type="entry name" value="SERINE_THREONINE PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7 10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="6" id="KW-0418">Kinase</keyword>
    <keyword evidence="5 10" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="14" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="12">
        <location>
            <begin position="11"/>
            <end position="266"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="334"/>
            <end position="356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="441"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="11">
        <location>
            <begin position="493"/>
            <end position="636"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="496"/>
            <end position="551"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="11">
        <location>
            <begin position="583"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="11">
        <location>
            <begin position="603"/>
            <end position="613"/>
        </location>
    </feature>
    <feature type="binding site" evidence="10">
        <location>
            <position position="40"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010886"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="12">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="13">
        <source>
            <dbReference type="EMBL" id="KAG2431324.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="14">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="636" mass="68317" checksum="A47B4E4AABBC38F5" modified="2021-09-29" version="1">MAKDGAKDRQFKVLKFLGKGSYGSVFLVQRLADSQTYALKEMDVRSMSQAEREDSINEIRLLASVNHPNVVCYNEAFLDGNRLCIIMEYAADGDLAKVIKKQQMMKRPLPEDMIWKYFIQVVMGLQALHGMKILHRDIKPGNIMVFDNGVAKIGDLGIAKLLTKTAAAKTQIGTPHYMGPEIWKNRPYSYTSDTWAIGCLLYELTALAVPFEARSMSELRYKVLRGTYPPIPNTFSRDLQQMVRECLDPNPDKRPTMDQILASAAVQSRVKLVPHESRHPPATAGSNLVETIKVPRGNIAAIKNKLPPAQYATDMLNIGNGPGGHAQMATIEEGSEDGTTGRLPPPHAPPQYQHQPARAPPAAAVNRVPNGMPPMPPMPKPNYPPPMKAAAAAYPPPAPSAAAGGKLPQLPGHNGGAMGNDNVSAAAAAYNARLAAAGLRPPQLNAVPPPAPPSHGGASAWSYAQAPGGAGRGVSESHANYGAFYHHSGYTPNSGAAARAQQQQPAPWQAGNKWPPQQQQQQGPQSQYQSPYISPYGGQQQQQQQQQQQRQYGGGGGGGLHLPQLAQRPQVAVNSKPPPWNYGGQARRQQGNARGAAGIAGARPGGHYAGDLGGSPDARVPSYPPPQWAPRPARGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835VZH0</accession>
    <name>A0A835VZH0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Pherophorin domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012531</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000061">
        <property type="protein sequence ID" value="KAG2433600.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835VZH0"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01217">
        <property type="entry name" value="PRICHEXTENSN"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="120"/>
            <end position="172"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="186"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="456"/>
            <end position="513"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="122"/>
            <end position="170"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="186"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="460"/>
            <end position="482"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="484"/>
            <end position="513"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2433600.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="513" mass="48761" checksum="6B62395F066F7A98" modified="2021-09-29" version="1">MVAAGFTAAAADVGALVVQPFAVASCVRGGGPLAGVLTPLMKICGGLLSADDGAKLQDWLEGPTGLAAWVAAIAGGPGSGSGGAGGSCAAALAGYLIYTEVADPAGQQTCLVGQYGSSCNYSPPPPQPPPPSPPPSPPPSPPPPQPPPPSPPPPHPPPPSPPPPRPPPPTVAACASITFAAAAGVPAAALSTSPVSPAACSATTSPTTRSTTSLTTRRRPPPPPMPPSTRTSLAAASLAASPGTPFSAATITAPARASAALATPAEPAAASAPASKPAAAQPAASLPAAITPAGNSSQSSSAFAAAACPSAALAPASKPAAANASASCTLITSQPLAAESTNPSTAFAASSVPAAAYASTSLPSSSQPTAAHASTSFTLTTSQPLAAKPTNPTTAFAASSVPAAAYASTSLPSSSQPTAAHASTSFTLTTSQPLAAEPTDPTTAFAASSVPAAAYASTSLPSSSQPTAARASTSFTLTTSQPLAAEPTDPTTASTASSVPASSRAASPLAAAP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W0N2</accession>
    <name>A0A835W0N2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Aminotransferase class V domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_012104</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000055">
        <property type="protein sequence ID" value="KAG2434905.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W0N2"/>
    <dbReference type="OrthoDB" id="5978656at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.640.10">
        <property type="entry name" value="Type I PLP-dependent aspartate aminotransferase-like (Major domain)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000192">
        <property type="entry name" value="Aminotrans_V_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015424">
        <property type="entry name" value="PyrdxlP-dep_Trfase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015421">
        <property type="entry name" value="PyrdxlP-dep_Trfase_major"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092:SF2">
        <property type="entry name" value="HERCYNYLCYSTEINE SULFOXIDE LYASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43092">
        <property type="entry name" value="L-CYSTEINE DESULFHYDRASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00266">
        <property type="entry name" value="Aminotran_5"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53383">
        <property type="entry name" value="PLP-dependent transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0472">Membrane</keyword>
    <keyword evidence="1" id="KW-0663">Pyridoxal phosphate</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="3" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="183"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="211"/>
            <end position="232"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="239"/>
            <end position="272"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="278"/>
            <end position="301"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="3">
        <location>
            <begin position="321"/>
            <end position="340"/>
        </location>
    </feature>
    <feature type="domain" description="Aminotransferase class V" evidence="4">
        <location>
            <begin position="325"/>
            <end position="506"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="48"/>
            <end position="69"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022898"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF00266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2434905.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="764" mass="78740" checksum="FDA4FF7D8CC7774B" modified="2021-09-29" version="1">MGGVVDIAKHFGLKAVYVLVAWGVTRVLEEGRKRFMRRRRRRSEETGADAAPAEAATVQPGTAAAANGGAPSGRGGSGGSGGRYRLYRRPLAEYTPSNPGWLREAVTYDAAALATDLSWQCPLLIQFLARKQLFALEPEVTYLNHGSYGAAFRLSLEVQQWYQMQLEAQPVRFMETVALKGRVGGLVLVLVLVLVLVLALVLVLVLVLVLVLVLVLVLVLVLVLVLVLALALALVLVLVLVLVLVLVLVLVLVLVLVLVLVLVLVLVLVLVLVLALALALVLVLVLGLVLGLVLGLGLAVLRGSMHWASQVPVKRAMLWRVVHVPAALVAAVADAARFVGASPADVVPVTNATTAINAVLAAAVPLRRGDWVLMFNTTYPAVKSTIARVAAAAGASVIEVTLGMEELQRPALAVGAMQSALAALGGGGRRVRLAVLDHVASFPPLVLPVAEMAAVLKQVGATVVVDGAHAVGNVPNLQVPALGCDYYTTNLHKWGCSPKGAALLWAAPGPGPGGGERQAALRPLVTSHGFGLRSVQANKHAHAQGFRGEWLWQGTSDMSPWLAVPAGLAVLRGLGGPERLTPRNAALVAEAAAALRQRWQAAVARRAAAAGAGAGAAAPAGAARARTSGAGAGAAPPTAAAAAAVAAVGPRPGELLLQLGGGGDWAAGSGAPCMLAVELPAPLRGYGGCGPAEAVALQRWLRYDRAIEVPVICAMGRLWVRLSAAAYNEASDYEALGRAVEELLLPPSDAVSGGGVAAAVAKST</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W0P4</accession>
    <name>A0A835W0P4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_012133</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000055">
        <property type="protein sequence ID" value="KAG2434935.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W0P4"/>
    <dbReference type="OrthoDB" id="560746at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="35"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="39"/>
            <end position="52"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2434935.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="387" mass="40924" checksum="673EE18481103C58" modified="2021-09-29" version="1">MDLDAAQERASTATKRAARLLWTLHAAPSLFAGGGDGVSSGAPGSSSARSRPGQPPRPHPEQLGLMWSVVAEHILPGVAEGLVRASYYPCIRQPGKHTAALFRPATAVLLWCRLLLTTLHWAQAAAATADAGAGGSSVRASDAILWRRLLLHDMDLFSLLANGVAFIQQDKQQPHTMAQGFTYGDGCGEDEHLFTLQRAAAELYSTAVLAAAVLPHECATAAAVPQQGTSTGSAAAAGAQPPPSRYRVPLPVDSIAQLFGPEGPCPNPDWQAAVRQAFASASAAQDGHDQQQQACMTHARAAVQQQPQAQQMQTAAALMVPPGHVRSALRRRYPDRRLWLCDNPVCVPAPELDASGWPLPPESCACAGSWAWCSGCECECSLYCSVM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W0Q8</accession>
    <name>A0A835W0Q8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Peptidase U32 collagenase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_012897</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000065">
        <property type="protein sequence ID" value="KAG2432764.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W0Q8"/>
    <dbReference type="OrthoDB" id="426032at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR020988">
        <property type="entry name" value="Pept_U32_collagenase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001539">
        <property type="entry name" value="Peptidase_U32"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011060">
        <property type="entry name" value="RibuloseP-bd_barrel"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051454">
        <property type="entry name" value="RNA/ubiquinone_mod_enzymes"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30217:SF10">
        <property type="entry name" value="23S RRNA 5-HYDROXYCYTIDINE C2501 SYNTHASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30217">
        <property type="entry name" value="PEPTIDASE U32 FAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12392">
        <property type="entry name" value="DUF3656"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01136">
        <property type="entry name" value="Peptidase_U32"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51366">
        <property type="entry name" value="Ribulose-phoshate binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Peptidase U32 collagenase" evidence="2">
        <location>
            <begin position="513"/>
            <end position="680"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="46"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="728"/>
            <end position="772"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1092"/>
            <end position="1141"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="15"/>
            <end position="37"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="728"/>
            <end position="741"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="752"/>
            <end position="766"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1119"/>
            <end position="1132"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF12392"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2432764.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1141" mass="117771" checksum="8EE7B9369C17D292" modified="2021-09-29" version="1">MLSTAPSRKQRQLQSSAATGATASASADVEAATAQQQQRRRYTPLTSKPEVLAPVGGWPQLRAAVENGADAVYFGLEDFNARARAANFTLEELPEVMSYLHARGVKGFIALNVLVFDEELGAVEQRVRAMAAAGVDAVIVQDWGVVELMRRVAPGLPVHGSTQMSITSGEGAAWVAGLGVERVVVGRELSVREIAKVRDAVPGTEVEAFVHGALCVSYSGQCFSSEAWGGRSANRGQCAQACRLPYGLLVDGVLRELGDVSYLLSPQDLMAVEQVPDLISAGVSCFKIEGRLKGPEYVALTTQMYRRAVDAAWAHLTGEGLPTEEEEEEEAAGGPAAAAAAAAAGGAAAAAAAASDPQAAARAAVALTEQQRWDLEQVFARGQDGQHRGLTPGFLEGVAHQRLVRGRAPRHRGVYLGRVAEVGPRGVVLTLQAPLKRGDGVAFDCGRPEAEEPGGSVYDILDGGAGETSLSMGAAGSADTNTPVPPGTRVTLVLGQGVGQAEVLRRVSAGDLVWRTKDPALEARLRASWDGRAAAEARRLPVTAEVSGRVGEPLTLTLRALDTIFTSPHTTASSTSTSSATATATASTAASATASTAAPTAGCTTVSASSAVLLSTAAKRPLSAEDVARGLGPNLGEATLVVPPGGLDVSGLELEAGLFLPASELKAVRRRAVEALLGARAAAALRTAAGMAPGPVLPGLLAAAAAEPAPPQALALVRALACTGPVEPSGAARPEAAAAPAEEVEEEERRVASGAAAGPSGVQAAGASGGGGGGGGGVCIRVLCRSRAQVDAALKVPWLREVVVDFLEVQGLREAVAAVRDSGRRVVVATPRVLKPDEQRLWLFYLRLGADALLVRSAGMLHTLQQLGGPGARVPDVPYPIPLLEGDFSLNAANVLSASLLLSSTGSSSAAATAAGSSSGSEEGAPAVWRGLSRLAPTHDLHAGQVAALAGGLGGRAALLEVVVHQHLPIFHTEHCVFCRFLSTGNSYKDCGHPCESATLHLRDDKGADHLVLADMGCRNTVFNARAQSGVFFLRDLLRAGVRTLRLELVDESPEAVAPLLEGYRDVVLGRRGPGDLWRWLATLPDANGAAHGVDAGSLQPAKERAKGGMKPTAAALKQQQQQQQQQQQGQGREAAGAGRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W107</accession>
    <name>A0A835W107_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_011539</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000049">
        <property type="protein sequence ID" value="KAG2436602.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="515939at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="228"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="615"/>
            <end position="650"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1258"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1331"/>
            <end position="1354"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="186"/>
            <end position="209"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="213"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="625"/>
            <end position="634"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1278"/>
            <end position="1293"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1331"/>
            <end position="1342"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2436602.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1531" mass="149104" checksum="9E9CA3F60003D248" modified="2021-09-29" version="1">MASEIPPHFRAALNPRELPAHRVERLWALHAELTSAPGLANAAAWLPAAWPHLLQLLNDAHPDVRAAAAPLVGHLGAVLAGGGGVSGLAPSTHGAHGIHTTAPTHHATATTVLVPVVQVLTPVALAPAPGPGLAYGAARPGVPPPHLTHMAHPTHIAHQTHIAVPIPLAAGGGPGPGPLPPFPPHARPRHAHPAPGHSHGHPQQHHHHPAPAPAASAPGAPGAVPLNPLSGRMPPTALLDWALAVLPADSKVAAAQHLRPEAKASALGALCACVAAMPAPALAPYGGQLLRLCCGLLEAASTPPALLGPLLRLLLAALPGVPLAALGHALSDLADLLCGWALEPAMASADRHLVTLVLHALRPQWHSHPAFAAELTCSMANDLTAAAAALAEAVGAASTAAIAADADAQAAAVAAAQQQVASCVPLLQLLVDIFSAISLRPPPPPDAADTATAAAAAAAPLLLTRPGAATAQNLLELYPQLLAATKGIAASLAQLGPLAAGGVDEGGSGAMTEEAMAAAAAAVCRCVAVLAEAAASCTPDEMDARDVAEVCEALQSGGTGGGGGSDGASASDIAGLLAAMTLDEEAGCESVVGSKQPSAAGPVSAALRAVTGKANGAAVSGSGGDSRDENEAAGRVEPAGPSSERGTEDSRRRCAALRAWVLRLGLDWSMGALAAAAEGSGAGALAAGGPAGGAELAALTELTVQLLRLVAAELADWPRLAAGLVVEAVLEETVGGNGEGCGGLRRLRASQRLALVSAAAKVLHGALLTARVDNGSSRDGSGNEGAAKAACSVAGSVANAALSWVLEDLSAQLASQSVEPPSLATKALPWPASQAHLMPRAASKAALAGGELYAADEAVAAGAATSGSCSKTAGEDISAAAAFDCAVLQAACQRGLLPTLAAAKVEAVTWTLLTASGAAVDAGAAPPPSVLCALFDAWAAAGLCTIVGLASQRPQPQQLQLASGDPEAADSLTASTTRALRSCCAAYLSTLHSLLVLLPRRAGSAAASSGASAAGATVTASLGVLLGASACSGSDGSGGNHALLAALQLRAVAALRRLVAHPAMAAGSATAPLRSARLFALAAESVAAGMASSDASVRAAAADCGAALAAGPHRGAPPCAAAAGPPAVQPAPAAALPAAVLPAEAYAPLLAAALDGLTDTSAPAAEAAARLAAELAEAALVAATAAGVPASIGSWLPDWQDELALAPQQWSLRLPQLVRLMEAVFGQAPVAVAVPTGAAGPGGAAGGGSALLLRKRVPGAQGGSGEGAGGEREDEEGGGSAGGGGGGGGAGGGAGGTGAGGVGAGGGNVGGGKMEVLHRLALALQPLVVASSPSPASSATSTGDGDAKPTAEAAEGQAAAGAVLKPQDVFAGRCSALLVGGRSAAALAWLAVQEGAKQLVAGRLRTHLGGPTQTLGALERMLQATYSRMSQERREARGVAPSLPLRSSSSRDGAWLLLELVGGLERAVAAAAEGVTVGGSGTGRKGGPGVGAGGVKAEAQLQAQQALPQPVLAFFAANRKKYTKYASCLPP</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W1S2</accession>
    <name>A0A835W1S2_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_011629</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000050">
        <property type="protein sequence ID" value="KAG2436120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W1S2"/>
    <dbReference type="OrthoDB" id="523142at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2436120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="130" mass="14714" checksum="DA12819AD00E28F4" modified="2021-09-29" version="1">MLVTQVAGSTITVFGDRVTHPASPKEYVRTYVKVPKEHDSKTPAAAVGVELTLGYIRRAQELPATVRMQIPLGPNMVFNYTGNDFNQMFPDVGYSPFTFLYWGFNWNGHPPPGIYDNPHFDFHFMMRVSA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W1S7</accession>
    <name>A0A835W1S7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">non-specific serine/threonine protein kinase</fullName>
            <ecNumber evidence="1">2.7.11.1</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_011643</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>L-seryl-[protein] + ATP = O-phospho-L-seryl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:17989"/>
            <dbReference type="Rhea" id="RHEA-COMP:9863"/>
            <dbReference type="Rhea" id="RHEA-COMP:11604"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29999"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:83421"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>L-threonyl-[protein] + ATP = O-phospho-L-threonyl-[protein] + ADP + H(+)</text>
            <dbReference type="Rhea" id="RHEA:46608"/>
            <dbReference type="Rhea" id="RHEA-COMP:11060"/>
            <dbReference type="Rhea" id="RHEA-COMP:11605"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:30013"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:61977"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="2.7.11.1"/>
        </reaction>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="2.7.11.1" evidence="1"/>
    <dbReference type="EMBL" id="JAEHOD010000050">
        <property type="protein sequence ID" value="KAG2436135.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="162894at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd05579">
        <property type="entry name" value="STKc_MAST_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.200.20:FF:000147">
        <property type="entry name" value="probable serine/threonine protein kinase IREH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.510.10:FF:001418">
        <property type="entry name" value="Serine/threonine protein kinase 15"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR058783">
        <property type="entry name" value="IREH1/IRE-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050236">
        <property type="entry name" value="Ser_Thr_kinase_AGC"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24356:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN KINASE GREATWALL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF26031">
        <property type="entry name" value="IREH1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00069">
        <property type="entry name" value="Pkinase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="10" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8" id="KW-0418">Kinase</keyword>
    <keyword evidence="5" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="3" id="KW-0597">Phosphoprotein</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="4" id="KW-0808">Transferase</keyword>
    <keyword evidence="9" id="KW-0862">Zinc</keyword>
    <keyword evidence="7" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="Protein kinase" evidence="14">
        <location>
            <begin position="894"/>
            <end position="1252"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1"/>
            <end position="30"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="123"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="182"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="340"/>
            <end position="367"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="485"/>
            <end position="685"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="862"/>
            <end position="887"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1049"/>
            <end position="1138"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1299"/>
            <end position="1336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1348"/>
            <end position="1380"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1406"/>
            <end position="1455"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1468"/>
            <end position="1614"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="127"/>
            <end position="145"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="189"/>
            <end position="202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="344"/>
            <end position="355"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="571"/>
            <end position="582"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="13">
        <location>
            <begin position="593"/>
            <end position="603"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="13">
        <location>
            <begin position="665"/>
            <end position="674"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="871"/>
            <end position="882"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1351"/>
            <end position="1368"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1468"/>
            <end position="1477"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1478"/>
            <end position="1495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1510"/>
            <end position="1531"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="13">
        <location>
            <begin position="1542"/>
            <end position="1566"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="1574"/>
            <end position="1585"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00012513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022553"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00047899"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00048679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG2436135.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1658" mass="175987" checksum="C119C4C08D93FE22" modified="2021-09-29" version="1">MDDLALLSRSGQAPGPGHFGQPGRSRAAPKRASVAGEAVIYEEQELQHPYPGVERSSSAEHRATHAAVRLASVPQAWDRCNSADGVDPAVAKQLATAVESKLKLAPLLAKRLERVSHSSGSFSSRSVTIVNSGQPVPSGRNTPQRRISGADYNKLNYLVTSLEGARGDRGLKVEGSARLPQVGFKETGGSPTTSKNGAANNHNFEEAKRQVDRDLRLFLEDVRDLYAQISLREGADVPIVLEVIASIMDIAEECLETPIEDFKLTITDIVDNIEEERSACQQRTIRALYTRLLFILTRCSRLLITEQQHLFATEPRNRRRHSQVFGPGFTTKTQKELGLHLPTAPQQQTSDTAGSTPKEEEEEPVFRSHTMPVKTMITMAQRLKQERPLDSGGWAEPPQLARIESEQLPESPAGPVGPVSASGQLELNTLRHQSQSSDLEGFGGASDSSMTSASKKKKSLFNKISKGIKNFVADGFKRKVKEGLKDAPDGLQRPQSEMGPAGHQQPLRFRIGSDPPRATDSPGGSRRGTKTGVSDGNLDGNPPAPTRKLDQQRSVRFQETPVTIIGENDDSASRRPPERDRTSGSCSAGGGHAHAHAHPHPHSHSGASLSTGGGTGAAPLSPDADADADLDLENGKRAKLMVNTEGPHTPPPTEPGGMGMDPSERTSASPQPSSELGARGTGRAKPFRRASVDLFALGHMMPPGTEPMSPDGAAPPDDLSVICSICEEAWLSTHLEEHSIHCAVLRTLSGNGLSIDAQLTTIANVLEEWLETPLAFPALGPAPNVFHVKNQLMKLIKAARNAAALQPDGSKVPTTRCFSIQAELGEMLETAEQAGKLAVVTQTYAHRVMRLISEKVNLLAETGGPRQRAQGGSDAGDSGTSTPRSMPGMSIEEFEIIKPISRGAFGRVYLARKLATGDLFAIKVMKKRDLIRKNMVESVTNERNILAMAQNPFVVRFYYSFTSRENLYIVMEYINGGDCYSLMRKFGALDEEVARQYIAETVLALEYCHAQGIIHRDLKPDNLLINAQGHVKLTDFGLSCVGVIDRTDNLNGSQPMDTDGPEHEGPDSTWGPSAEGNGDAMDASGPRPTDDGPISNISLDGALQSGSQHGGANGRMSVPGQALGGAASSLGLPPRPVGQHQRIVAPEHESRRAVGTPDYLAPELLLSTGHGPEVDWWALGAILYEFITGAPPFNADTPEEIFDNILDRRITWPDEDDMSCDCRDLIDKLLHPNPLKRLGHRGAGEVKLHPWFEGLDWTGLVRNKAAFIPAVEDETDTSYFESKHVSQRSMAEDLDKLRTSVAGGSERSSAQVGPCSGPAQLGVGPSSGPPGGRTQVDRLKDAYYREGSGLRSVGSSNSHGSSHMSRTSYTGQAGPVASGGQMMQCGPDLTSLDAATVSRMCSSPSHAIHAHMHSSGPESATMPHGGSYGGPRHSGNVVSVASGSLHPRNSVGSSSGVAPLLLGGVGARNSGSGGRNSGSGARNSGSGARGSASGSAGAGGMSERPSPGSIGTGAGGTMSGLNTCGGTGEGTDVGSMRGAGMYEEEAEDGYPDDEDYVGEEGVEVEVEEHNGEDNGAGLGDGGGPNSGRPRAGVLLDEPTAGTVSGSGDEEGIDLSHDPFNNFSFTNFTGLSAANMEKIQKLREHFNRRTSYSGPDQGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W2T3</accession>
    <name>A0A835W2T3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SEC7 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_012165</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytosol</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000055">
        <property type="protein sequence ID" value="KAG2434969.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="430364at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005085">
        <property type="term" value="F:guanyl-nucleotide exchange factor activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0032012">
        <property type="term" value="P:regulation of ARF protein signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016192">
        <property type="term" value="P:vesicle-mediated transport"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="CDD" id="cd00171">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.10.1000.11:FF:000002">
        <property type="entry name" value="Cytohesin 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.220.20">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.1000.11">
        <property type="entry name" value="Arf Nucleotide-binding Site Opener,domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR056604">
        <property type="entry name" value="GBF1-like_TPR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032691">
        <property type="entry name" value="Mon2/Sec7/BIG1-like_HUS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023394">
        <property type="entry name" value="Sec7_C_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000904">
        <property type="entry name" value="Sec7_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035999">
        <property type="entry name" value="Sec7_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663:SF388">
        <property type="entry name" value="GOLGI-SPECIFIC BREFELDIN A-RESISTANCE GUANINE NUCLEOTIDE EXCHANGE FACTOR 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR10663">
        <property type="entry name" value="GUANYL-NUCLEOTIDE EXCHANGE FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01369">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12783">
        <property type="entry name" value="Sec7-like_HUS"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF23325">
        <property type="entry name" value="TPR_28"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00222">
        <property type="entry name" value="Sec7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48425">
        <property type="entry name" value="Sec7 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50190">
        <property type="entry name" value="SEC7"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SEC7" evidence="3">
        <location>
            <begin position="590"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="486"/>
            <end position="518"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="540"/>
            <end position="568"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="486"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="505"/>
            <end position="515"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="540"/>
            <end position="560"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004514"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50190"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2434969.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1506" mass="163827" checksum="55AA46BB04D9B79B" modified="2021-09-29" version="1">MTLHRGSPAAHTLLLNHEIASVITAMRHNAKWAMVPRYYEEDRNEPSKYDDAFRALRSEIFKFQDWRDVDPMIYLSPFLNLIKASDVSGPITGAAAVALQRILESDLLAPGTRNVEQAINQIVEDATQCKFESTNNSSDEIVLLNIVQVLGQAVDSAAGCFLTDESICKAVQAAFMLGDPVKKPKEYGDIMGYYSRQTCGAMIRTVFKNVAEQLLAAQAAEMNQQPVPEPTCRYGVRAAVNILEFLIDLIQKGPSLQGATKETVEEMVVFSLDTVHAVICVAGGALVLAEPLARLVQVDLLYSMCQAVVQYSSVSVITGFCQTLLAISSYLGHVSMAQMETVLQRVLLKLADGKGVLALEQQEAALEGLLDLVRQPNFVHDMFVNCDCRVERANLFEEVCSLISKTAFPVSKTSVGPLNFISLEALLAILNALAQSARNGQELLAAPSPANELPFYADLWGPLVAGTHPDLGALADVLLAPHPFTHHHHHHHLHHNTSHGHGHTASSKSLTTSGSAALPEPGAVLSAAEVVAAEARSAASATAGAGPGSTASGLTTAGSGLPPGSGAGVRGVPVTGPLELRCAMAERCLKARIGLAVDHFNKDFKKGFVAMQAAKLLPEQPPANTDPEAAAAAKKLLATRLGHFLRTCPGLNKTTIGELLGDPDPFYLEVLEAYTTGFDFAHLKFDSALRMFLESFKLPGEAQKIDRIINAFGRHYYAGNEDVFRCADAAYVLAYSVIMLNTDQHNNQVKNKMTLESFQRNLRGVNDGTDFDKRFLEEIYYSIVKTPLRLSEPASMDVSEQCFLQLAQVSGTQRGLVLSSESGRHLFDTTMFRLIWGPAVHAMCAIVDNCSNEALIGSALEGLQLACQIAAAHELEDVADSIIVNLSKIPLQQLAQVPASARSDVVFGRDPRLRAVTRTLAAVINKHGDSLRGGWANVMDLVVQLYRRGLLPDSFCRALNGDGDGGLVVRDGECSSLRARRLALQRAGTANSGTSSIFKHISSFTQILSLSSEPTGNDPSTGRGNTNSIAAAAAAMEAANALLSEPERAAVVAAEDCLTKCAFEDAFMDSKFLKQESLVQLVRAICGSGGPIPRPPSSSMPWDASELCLELLFTVLLRNRDRITLLWPRAYEHFATIFQHSRECDTVLVQKAIMAMMRLCQRLLPYKAADISEPLMRGIQLLSLVDEQVAHDLASTIAAEIQSLLQGAAAYIHNQQAWMSICALIKVIHLDPASYPVCLDTITWVVKESLSMLNYHTVVSTAVDLLERAVPDPRRGERPGHPNHIGQAIRLVQSAEEWLELWWISSQSKHSPEALDRLGFLAFKADTWHLLIGWLCRLAKNTSVEVRTGTMSCLQRTVVAAERLIIPAPGLARSLTELLLPLGHDLVKLMHSRDMPQCDVTVRELVRALSKMVLLYHTQLESLPSFGAIWRGILDVLAAAAAANRQQGEVLAEALPEALKNMLLVLHSKGMLVEGWKDAEGVDLWEFTWRQTARTAPSINPQSIRS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W342</accession>
    <name>A0A835W342_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_011187</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000046">
        <property type="protein sequence ID" value="KAG2437545.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="545516at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="121"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="251"/>
            <end position="290"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="426"/>
            <end position="449"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="667"/>
            <end position="694"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1086"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="162"/>
            <end position="187"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="259"/>
            <end position="269"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1086"/>
            <end position="1106"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2437545.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1292" mass="126450" checksum="492F91D84C15005C" modified="2021-09-29" version="1">MPVNFICCFVGSQLPGDEDTAKHAAGRARAKAEKETQTSARCLEGYIIPSAAAQQATGAETRAASDAAPSSGLVPASTPAAALLLSTPLKSAAIRAVGPSSSPSSHGVTQAAHVTYVQPHATPASQASTLRAAELETPERAAPPLAPASNLSDSPIASVRTAPSAPAHIAPAPSSGAQGAPAIPSGARLPPLPPSHGAATPGRSYVGGGSGGAGLSPIPSSVAAGRQSGSGFLESASRQLARAAEPLPYVSYSVSGGPQPLGGGGGGSHGDADGDEYDEAGDRTSAASSVAGRGIRGVSFGSGAGAAGARASSSAAVELGAGGGGVRTVRLPRGLRSPRTSNRALLTRQRTPYALRRYMGGQLVGPRELLDLPAAPSPAVGTGVGATARSHFGAASPSAARAAGTPSYANGGASFRSITTAAAAASAAGRRMHTHSGAAPSEPDTDPAALLDRNSAAAAPGSSARAAAFNAAARSAAIARQTAVRFGVRPLDPGAPSPGPEASVLSPRTTAPALLARQATPCPLRWGRLEDSWDGASEAALSHTLSNTFSHTYSNVMNAVSEHGAPPNFDAGGGGMDVFRYGGRSRAGGAISAMGGGNGSSMAGGPGDHSDRLSAGGVRGFSRAGSIRSGRLPSYGGGGTGAGFGGHQPHPHRALRVNVSLAKSRRSSVSSVMSLDPTEHGATEGAAGGATGGGGGPALPVVVSLRTGGGGGGNTPTRRGRRRNLAGNEVLGWETLVPRVPIAPMGAPDATSSVATPTAFAGAGGAAGGLHIPMPLPPSVGSLLRGSSAMPMPLSLMQPGGVGGGVGGACSSLLPPGSSLPPVNSLTTGVSSVLNCDNISCNSPAGVPGASGSAGAFPGPGWRQPPGALAIPLLQSAHSQPSPKPQLVSPPLHGVAVGVGGAGGRSGGSSMGQQVSFQPLMGGPPLAGIRTREMAGHMEPQGSAFPRPDLPPAPELAAELAPVSSSRGSSIAGNTLGAQPLTGFRFVPSGGGGAMGIASRVSGNGMAGGSWYGTRGTQSSDGRAAIPMPTGYASGAKSPLAVVTTAGGGLAPGGAAHTLRRSCLSMSRPASTANIASAAAAAAAVALPHHQQQQQQQQLGQYHQQHGGISNTEPRSTDGGCPTSGRLAGGASGAGRRVLQHAGSVRSHAPTEDDSAESLVKLAQAATWETNNNITSGTSGYHGNKAADDITTSGDMFATAAHGAGGARAADEDAIASGLIVLGGEDPQRVAPAAPPPTTGIAALVSPTPVPGPALTPVSLASPLRHVLGNGPPSSRLSRCTSLAQHEAQLLR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W377</accession>
    <name>A0A835W377_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">DUF1365-domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_011903</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000052">
        <property type="protein sequence ID" value="KAG2435613.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W377"/>
    <dbReference type="OrthoDB" id="3340520at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010775">
        <property type="entry name" value="DUF1365"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR33973:SF4">
        <property type="entry name" value="OS07G0153300 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07103">
        <property type="entry name" value="DUF1365"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="65"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="269"/>
            <end position="296"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="353"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="65"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="75"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="278"/>
            <end position="294"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2435613.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="353" mass="35802" checksum="0EB407DC18774871" modified="2021-09-29" version="1">MAVVDLERPPAWFARRQAADHMTADQARSFAGTTGPVKLLTDPISAGYIQNPISVYYCYSGSSSGSSSGSSSSKEAGKEAGKEPKLERCIAEVTNTPWNERVTFVFDPAGAHVAKALHVSPFMDMHNTWHLEVPSPGERLKLVVRASHPVYGDYFHADLVARRCSSGGGGSSGGSSGGSGKEAGGVLNEEAGLGRLWAYGFMPHRVAFLIYWQAVKLLGKGVPFYAPPSKGYQRLLVAEGPGPGLMGSGSGAAAKAAGDKGKACSAAANGRAADGSSSSGGGSGGGGGGGGGAAAAGTGAADATVSACGGAPGGLCPVAAWSRGSSGHSHPRNAMNGKHFVWRPAPGWPWRDS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W379</accession>
    <name>A0A835W379_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="16">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HYH02_011288</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000046">
        <property type="protein sequence ID" value="KAG2437650.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W379"/>
    <dbReference type="OrthoDB" id="423462at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0089701">
        <property type="term" value="C:U2AF complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd12539">
        <property type="entry name" value="RRM_U2AF35B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:000122">
        <property type="entry name" value="Splicing factor U2AF small subunit"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003954">
        <property type="entry name" value="RRM_euk-type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR009145">
        <property type="entry name" value="U2AF_small"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12620">
        <property type="entry name" value="U2 SNRNP AUXILIARY FACTOR, SMALL SUBUNIT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00642">
        <property type="entry name" value="zf-CCCH"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR01848">
        <property type="entry name" value="U2AUXFACTOR"/>
    </dbReference>
    <dbReference type="SMART" id="SM00361">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="8" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="3 12" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="9" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="10" id="KW-0539">Nucleus</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0677">Repeat</keyword>
    <keyword evidence="7 11" id="KW-0694">RNA-binding</keyword>
    <keyword evidence="6 12" id="KW-0862">Zinc</keyword>
    <keyword evidence="5 12" id="KW-0863">Zinc-finger</keyword>
    <feature type="domain" description="C3H1-type" evidence="15">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="domain" description="RRM" evidence="14">
        <location>
            <begin position="65"/>
            <end position="147"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="15">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="12">
        <location>
            <begin position="12"/>
            <end position="40"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="12">
        <location>
            <begin position="149"/>
            <end position="176"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="190"/>
            <end position="260"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="195"/>
            <end position="238"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="13">
        <location>
            <begin position="250"/>
            <end position="260"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG2437650.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="260" mass="29778" checksum="336D7504EA649FCC" modified="2021-09-29" version="1">MAEHLASIFGTEKDRVNCPFYFKIGACRHGDRCSRLHNRPTISPTILMANMYQNPLLNAPLGPDGLPIRVDPRAAQEHFEDFYEDVFEELAAHGELENLNVCDNFADHMVGNVYAKFRDEDAAARALTALQGRYYDGRPIIVEFSPVTDFREATCRQYEENTCNRGGYCNFMHLKPISRELRKKLFGRYKRRERSRSPRRDRDRDWDRGDRGRGRSRSRSRERGGGDRRRETSEERRAKIAAWNTERDGGGGGGGGGGGW</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W5X7</accession>
    <name>A0A835W5X7_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_010802</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000043">
        <property type="protein sequence ID" value="KAG2438344.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W5X7"/>
    <dbReference type="OrthoDB" id="106784at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="322"/>
            <end position="360"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="29"/>
            <end position="41"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="79"/>
            <end position="89"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="108"/>
            <end position="137"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="138"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="160"/>
            <end position="173"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="198"/>
            <end position="215"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="223"/>
            <end position="236"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="266"/>
            <end position="278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="279"/>
            <end position="292"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="327"/>
            <end position="360"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2438344.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="360" mass="37084" checksum="F4A9FB85B238F785" modified="2021-09-29" version="1">MLLAAPAGTKRAAPDAGSQEDGVQEQRPGRAGSSDGGAQASGRGGSRSRSRSASPGSDSGDERGGAAAGSAQDGDGERRSHKRHKKDKKEKKDKDKKDKRSHKKKEHKERSKSKGKEKDRRDKERGRDKERERRKGGDAAGGDAAGGGAAAGDEAFVDNFVDDVPYEDLDYEDQGPPRRSPPPRAAARSAGGGGGGGDRYESRERGDRGDRGRYQDEDDGGRRGGASGGSGRGSGGAAERRGAAATALATDDGAPRRSRIEWIMPGSSRAPAAVAAADTGGGSGAGRRGGGASDEPPPVSSARGAGGGGLAARLFKQTLGAAANDAASRRLARDDSRDDGGRRRGDGGRDYDDDGRGRRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W694</accession>
    <name>A0A835W694_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">dihydropyrimidine dehydrogenase (NADP(+))</fullName>
            <ecNumber evidence="2">1.3.1.2</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_010693</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="pathway">
        <text evidence="1">Amino-acid biosynthesis; beta-alanine biosynthesis.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.2" evidence="2"/>
    <dbReference type="EMBL" id="JAEHOD010000042">
        <property type="protein sequence ID" value="KAG2438898.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W694"/>
    <dbReference type="OrthoDB" id="4327079at2759"/>
    <dbReference type="UniPathway" id="UPA00131"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0017113">
        <property type="term" value="F:dihydropyrimidine dehydrogenase (NADP+) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050661">
        <property type="term" value="F:NADP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0002058">
        <property type="term" value="F:uracil binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019483">
        <property type="term" value="P:beta-alanine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniPathway"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006210">
        <property type="term" value="P:thymine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006212">
        <property type="term" value="P:uracil catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.30.26.10">
        <property type="entry name" value="Dihydroorotate Dehydrogenase A, chain A, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023359">
        <property type="entry name" value="Dihydro_DH_chainA_dom2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005720">
        <property type="entry name" value="Dihydroorotate_DH_cat"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43073">
        <property type="entry name" value="DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43073:SF2">
        <property type="entry name" value="DIHYDROPYRIMIDINE DEHYDROGENASE [NADP(+)]"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01180">
        <property type="entry name" value="DHO_dh"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Dihydroorotate dehydrogenase catalytic" evidence="4">
        <location>
            <begin position="38"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004668"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00013004"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF01180"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2438898.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="185" mass="19678" checksum="98220C5F4E2F4C8D" modified="2021-09-29" version="1">MYASVAGAHITAPALLWYQAGVNLDTLRPEPSVEGYSTPGGYSWKAVKPIALAKCTSIAKLIARDYAGQGKSLSGIGGVETGGDAAEFILLGSDTVQVCTGVMIHGYPVVKNLCGGLQKFMAKHNFKSIAEFKGKSLPYVTVHSELVKRQRDAISAKKARQGLANDAEWSGEDFVKNADSMAVNR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835W9D8</accession>
    <name>A0A835W9D8_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_010109</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000036">
        <property type="protein sequence ID" value="KAG2441266.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835W9D8"/>
    <dbReference type="OrthoDB" id="542320at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2441266.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="116" mass="12638" checksum="6AD99CFB915DF40F" modified="2021-09-29" version="1">MMATMQSTVRAARSGLALAGRLPGTRCNFATDASASTVVYPGAPEESKEELEARKRRSVKAYLEEQFGRDDPDRSSLAVLLQQHGVVVKGGHAEAVRLIEALVAWKRGDYKPDIPQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WCX4</accession>
    <name>A0A835WCX4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Replitron HUH endonuclease domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_008987</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000028">
        <property type="protein sequence ID" value="KAG2445120.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WCX4"/>
    <dbReference type="OrthoDB" id="1990019at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR054424">
        <property type="entry name" value="Replitron_HUH"/>
    </dbReference>
    <dbReference type="Pfam" id="PF21859">
        <property type="entry name" value="Replitron_HUH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Replitron HUH endonuclease" evidence="2">
        <location>
            <begin position="10"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="445"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="448"/>
            <end position="464"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF21859"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2445120.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="464" mass="50728" checksum="BCE59E8F33F00B65" modified="2021-09-29" version="1">MRVARVIKHYEGTRRCAVAYERGTDAEHGHLQAVIEVDGTSAAAASKWVQRILAGLRGLHVRCVSLTQNGMHTFKGMLGYVCKDAGQPHFRLVIQGVTSTELLEGLGEYALYGECCLKKRKELGHTNWMERAFHWVIARCGGFTDSRFSVSATLTAMIRSGKYYPSAAWSLVRWGGAAMVDRAKAETIWRMVAAPADTRQEDVNRVFFSKPTYDDRYFDDSAGWEDGADDLCLAEHNPLERLMPYLPQDAFGTDGIPGTILVRPPQDAHARLYSPLFGDLGVTAAELEEALAAPNHAPGGLAPDADPSPAPSMQYVVVCPRCTDDVTFWPSEFKVVVLERNCLCNSCWDDALEVRKVRAERKVRRESDVVVNEGASGSVPRVGQKRGVAYECSEVVIPGSAAPPEPPSKRRVPTITLVTSSDEEWDAEAAAAVDAVEARQAASALIEAEAEEGEAEDASELLDE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WCX5</accession>
    <name>A0A835WCX5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_008878</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000028">
        <property type="protein sequence ID" value="KAG2445009.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WCX5"/>
    <dbReference type="OrthoDB" id="560709at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005634">
        <property type="term" value="C:nucleus"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0043565">
        <property type="term" value="F:sequence-specific DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14312:SF1">
        <property type="entry name" value="BASIC-LEUCINE ZIPPER TRANSCRIPTION FACTOR A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14312">
        <property type="entry name" value="CREB/ATF BZIP TRANSCRIPTION FACTOR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="483"/>
            <end position="509"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="166"/>
            <end position="196"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="243"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="551"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="646"/>
            <end position="675"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="167"/>
            <end position="194"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="552"/>
            <end position="561"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="646"/>
            <end position="666"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2445009.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="803" mass="81097" checksum="77995EFB3264D879" modified="2021-09-29" version="1">MIKDASGHWQLAVVQWPTPSIVYRKTQYGTAISHQGVLLSRRAGAVAHLNRVASGNILVLPQCSSFCNLGAALLLLPVQSYPATLVPVAANGRQEAAAAAAQAAPQQAAPAAPAIVPSNRGGIDSALVRRLAGEALHAGVVTGELEDDKAVLTARAAQHNLRVAHAAPPPAAGCSSSPPPAAGGRPSSPPPPPGDVAERVVQQLMMGARARAFSAPIATAMERLIAGAPLQQVVAEALQGRSASLAPPPGAAAPASATSTSAGGPTSPAPSAAASAATAAAAGSTSAATAVAGPLDGQEAAEVVRDLFVRLCFLLCGCGELPDELLWRVACAWRAGLALPPDVVEGMSALLRRRELLAATCLFYESAVLDQRRQQAAAAASSSSSAWRGWPLFRRRTPQQVAASIRVTSALAFMGPGSREPTLRLTKEVDTRGAGRYRQLLERLAASLAAPASGPYCLLTHNCQDYADYIATGAMARKAARKLALGSVLGVCAGALVVAAGTYVAWRWWFRPPAQSSEPEDVCTVQDFLGLSEAQREACLRACQQQQQQQQSEEEAAEAEAEAVLPRRHHSEEGAAPGDVVQDGGSGGGGSGSYDDHDDTLMDGSQQMAADLNTFLANLRQFYASSDRPAAPAAAAADAAAAADVASSPTSSPTSVSPTHAPVSAGSAGGGGGEAAGRVVDVARVQRAARRLRQDNQVLEAAVRGFGAQATPVVATLGVGSAALSLLGVQQHSAPTPYVQQAAAAAAAASTAAGGGGERVGGGGSGGGGAAGGAAGGTGSGEIDAADVARMMRYLNVLCEGST</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WD84</accession>
    <name>A0A835WD84_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">O-fucosyltransferase family protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_008932</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000028">
        <property type="protein sequence ID" value="KAG2445065.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WD84"/>
    <dbReference type="OrthoDB" id="533531at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd11296">
        <property type="entry name" value="O-FucT_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.11350">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.550.10">
        <property type="entry name" value="Spore Coat Polysaccharide Biosynthesis Protein SpsA, Chain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029044">
        <property type="entry name" value="Nucleotide-diphossugar_trans"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53448">
        <property type="entry name" value="Nucleotide-diphospho-sugar transferases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="101"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2445065.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="882" mass="93190" checksum="4E703845F5DB774D" modified="2021-09-29" version="1">MSIGSGPHQRGKGAEQGDAEAGYKLASRGSGGQLQFNGAGTPRPRVASSLSLSATLRKSLLLAIVLLVGYSIGAFNHRCSLSTSASGRSFVQQLTAALAGGGDGGHGSSSSGGGGGFGGFGGTDGSGSSSRAWGTAGAGGSSSGLGDFAPVNKTLRFPVCNGFANQRLSILYGMVLAKRLGRAAVLPVLVDNGLQRGDSAVLATANNQIPFEEMYDLPHFVSSMAGAGVHVLRPADAPPANTVLRLAGLSRGQQGGVSEALATTYASIRHIAIDCPLFKLGAEEMQPGFEPLVWATLNGLRPSKEAAALVDKISRAISSKAAALSRGSISSTGSGTGSGSASAAAAAAVAAAAASAADANLLTAAGAAAGGGGAIRVARSRALQAASDWAAAAYGPARPFNFIHLRIENDWIEHCRRWESIRDGIVRDNCYRHTEEVAAQLALFGFSNSTPLYVGSYWDDVEPGRREQALAKLRAAGYILVTSADVFPSSSSSSSAGGAAGASGAGGAAAAAAAPNPLEGRGREYRAMIEYFVGLRAQRFIGNSVSTFAALAMLERRRAGRWAAYYNGGNIPLASVLPLLHRLPWVFTYNSWSGQYDYLLKGAVRSALATRSFQPYCIFMGNESAAIHTWLVAHNVTVISHTPAWREQLLALAGRKAQNNVAHSHLYKTPDSLVSTFQRVDLPVVPVLDQYSYVLYTDADVFFRRPIRLDDFGLPLPRSVSMSYEMDPMFPYNAGVIVANLPVMRANYKAFIAMMLDPGASEGLYYPGYGPADQGIINKFYESDLRGRMLNQLFNAKPYSTFDASAYILHFHGPKPHEYAAYLNTGQCDFKGLCEKAFAMSLCRYTREWARWVPEEPVALRLGDACGLLDNPAFQRLRGPTS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WIB3</accession>
    <name>A0A835WIB3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Lipid droplet-associated hydrolase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_007117</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Lipid droplet</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the AB hydrolase superfamily. LDAH family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000019">
        <property type="protein sequence ID" value="KAG2448093.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WIB3"/>
    <dbReference type="OrthoDB" id="448051at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005811">
        <property type="term" value="C:lipid droplet"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016298">
        <property type="term" value="F:lipase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0019915">
        <property type="term" value="P:lipid storage"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR019363">
        <property type="entry name" value="LDAH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390">
        <property type="entry name" value="LIPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR13390:SF0">
        <property type="entry name" value="LIPID DROPLET-ASSOCIATED HYDROLASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF10230">
        <property type="entry name" value="LIDHydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0378">Hydrolase</keyword>
    <keyword evidence="3" id="KW-0551">Lipid droplet</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004502"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00008300"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022677"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022801"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2448093.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="385" mass="39906" checksum="7D58F1FDA9E708DE" modified="2021-09-29" version="1">MTGDGANSELSVLLARPWQEHRDVGGVRTELLGIEASTGPERLQVLVIPGNPGSAALYVPFMAHLHALLGGHAHILAASHAGHDGFSHHGGQVWDLAEQVAHKAALLRQVALAPGRPPLLVVAHSVGAAMMLRAIAQVEGWALLEGGGDPPLQEAAGPALAAADSCDGGGGGGAGGWPTAASAAAGGTTPAVLKLVAVFPFLEAVPRSNRRQASIRMLAAWHGCLGWLGGCLAAALPRALLARCLRLGSDMATGMADAIAARLNRSTLRNALYLAADEFKVLSEPWPWPQLASGLGRRLHVMGCDEDTWLSRAQYEELQQRVPGLQATWHSKLRHDFCVSEAQSKAVAEHVAGIAHGGREAQLPSGGGAAVEAVEAEAGHAFGKL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WIB5</accession>
    <name>A0A835WIB5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007371</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000020">
        <property type="protein sequence ID" value="KAG2447917.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="534644at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="148"/>
            <end position="167"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="442"/>
            <end position="463"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="508"/>
            <end position="565"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="614"/>
            <end position="703"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1181"/>
            <end position="1200"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1320"/>
            <end position="1340"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2154"/>
            <end position="2204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2218"/>
            <end position="2260"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="2371"/>
            <end position="2397"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="616"/>
            <end position="632"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="664"/>
            <end position="686"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="2169"/>
            <end position="2182"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2235"/>
            <end position="2246"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="2380"/>
            <end position="2397"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2447917.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="2501" mass="249968" checksum="E5CD19B5FFB06ACA" modified="2021-09-29" version="1">MAAGASDGDGDEQQQQLRAAVQDFVGMPAACILLLRDLLLEDAATASDAKQALLQLLPMQLEAVDSCGSGVAGGKDKPRVSLKTKLGLGNGRQAAGADNGCGASSGEGGAAVRSSNRIALSLMLYLFCFADSAEQAHQALMAPAAAEDAGSGANGSTSSGTGATPSGTKQAVQKLLKACAATLRAAPLVPGCGDVPVDLLRPLQGLPELGSMSAPWEAASGTLLPPDATALEERYGLSLVSVYAAHDYGLMMEQLLALKLQVEAAAAAAAPSVEAVLSGAGGSSQHAAGNVGAATSAALLGLPQPAQVALGRLAAGVAGRALRLLQDWQTAVLQLDTLRTWQQQQRRLRDAEEAGDAVVLTSASRCAMTGADATDVVRMVAYVKGLAGLLQESLPWLEPLLAAHCAAQLGQLLSAVLAPVAQGTLAMPPAAEATGAAAAAAFGLPPPSPSRARGGDSITPSGGMSALDSNFAAATEPATSAAGGNSAALARGLGRLWKAKAASHRRNVSSEALDNLGSLTPPGAPNEAEPEADDADTPGTPLGPPPQGIPANWTPSRVNDFQPDPYTRLRDWFASGNTPQKGAAAAAGGDAGAMALLGAAPLDLDAPLATVMEGLTPRSGTGTPVPGSGSRQRPPRPCASPGGVARVSAGSPSAIRGLPPLPRQSPQQQQQQQHNTPGGTTDATGTEEGGRGEDVECTVSSASERDPQELVGMQGAGHQAQASLDLDSGSFARYQGGMPGYGHGYGDSSLCPPPQLGAPPLPPLDAVPAAPFWLQQGGTDAGFGAPALDENFGGVQAAAVSGPGRAPGSVAGGSGGGGACLTNPLFVYPSEGGRLVATRATDPTAQQQHKGTVEVWVGGKSDGGAAASAAAPPPLALPQEDGGLHMYGGAGLLGAYAADAQAGGMGESGPAQPVPNKKSSSRFKSIKKLFGIRRAPNSTSGDGDSSKDVRQQYLTDGVGYIAAPPEAAGAAHFGFDAPMLDDLHMSAHVDKYGNAAHLSPMSGAPAVHGFGGVPLPSGGEQQQHYGMAVGEVGVVLDEASASGHQESALHEGLNRDGAFAMLSVGPQGAGGAQHKEGAGGKAQQQQLGRFLEVVAQASRKRDERSCNNLQQLATELQMFLSSAGYALGSNGRAAVQLPAPAGGAEPSINVEATGPPGGIRKASTSLGGAKASIKKLVTSFKGRSNGGRQASAGAHQDGPAMPALASPAEYSSMAAGPVYGSSLPAAQQAVVLEERDVSRLKMTLEMMAAELAALVAHRRLLPRASKASGSTSGPSLVSLLALSSELQMFLAQTFPPLMPLLAFRANVAVAADLSALLATDPARTAGPNGPSGARQSSSDARGSMPWELVCRGILAADSGGPSSADARRGGAGGVPLASALTVLSLFGDAVEAAQAQELRSDCPDTQNALSRQQQLYRRQAKWCLDTFVHAAARRIWATYKAQALRSELGVAVPPGAPDVAPDTAALQDLMLLQPQPLQPRWGSQQQTRGAPGPRCADSCALVQLQALVVAVGGSSGAPELQARLAAAVDDLVRQCAARTAALALGSDLTALAAVKQQVDVLSAAVARVHLELPGVRPWADTWLGALAAAAASAPTCAPIAEAAAATAAAVAQGCSAATAAAAAGGDGLGVGVDDILMTHMTSEGVLRALSTWAYDMRAVQFTPTKHTRNYWEQLCRASAAFQAVASPPVHRLDGADLALAAATAGTSGDGGSSRAAGSSNGAFGRPQVLALHSLLGLDGVGRLVAALRSHITSLLTDASPLLRRVHELYDGGVAGPRGPGLRGAGGAMGYLQLQQRWLRDRGHTDMLVSANRAMQAIGNSVAAVALLDSVLAELAACRSPHLLPLAASTLQADQCAHAALQAMANADAAAAGASSLLPPPAVSAVAPPPAGTGFAGLLLGLQGGLPPGLAGASQPAVAAAALVQDRIREQLPPAFGLPGLWRAMFEAIHQHAAPPAQRQPYPQQVQGQTLFAPARLWCVLQTQLCCLTPEEQAVHAANVGDGVYVAAAAAVQLATGAPLTPGSVLLGDTTTALQQAAALEAMKAQLATVSTASGAPTGQSAAAAVAAAAATLEQLQAWSARAELVRSSWDAAVQLTVGAGATAARLAAEPQPDRAALLASCLSQAPLTAWAPEPWMALVSQAALAGAAMQLRAAAPPPPSVSVPSQQVPGGGPGGHSMGGRAGQAASGSVVPPPSAAGGRLPPGAVRMHSTLRLLIPNQQASQPQRGPPLPSRNSSGAGAGMAAPGGASGGPDLSRASAPQPRQLLSAQSFSGAVGGVVGPGISSTGGAVAVAAGSSNAPPVLSAGPLMGQAWNPQQPQQQAAPGQAVLRPSPFVLQQAAAAASAGQQVRQLPAQVRGMGLVDPSVTPAGYGAAPPPQPLQQLQSMHSSGSHAMHSAPHPYSAAAAAAMAQPEPQLSSYLSYGGGGVGAASGGYGDVMGSAGGASMLPQSMIYGPNAFTFASNGGGGAAGPVCMSGGGEYEAGSVAANSRSQYGSDFAADE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WLF1</accession>
    <name>A0A835WLF1_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">SRCR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_005567</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449418.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WLF1"/>
    <dbReference type="OrthoDB" id="535306at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.250.10">
        <property type="entry name" value="SRCR-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001190">
        <property type="entry name" value="SRCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036772">
        <property type="entry name" value="SRCR-like_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00202">
        <property type="entry name" value="SR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50287">
        <property type="entry name" value="SRCR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="SRCR" evidence="3">
        <location>
            <begin position="83"/>
            <end position="136"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="92"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="250"/>
            <end position="273"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="46"/>
            <end position="58"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="251"/>
            <end position="269"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2449418.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="445" mass="47355" checksum="2B846D0790B892F4" modified="2021-09-29" version="1">MDQVAEARPRSALLPPGKLDTSRKYSPPRRAPPPAKATVPSPKTISPSPLVAPVSLSPVPLPSPRAQPSQSGPPLAPREGNGIRLVGGSGSRGRLEVSSLDGWLNEYEEGAVAWRPVCNMVGFDDNDAQVMCELLGYTYGRLYYSDEVVRRAPNDTATDIDMPIENLDCSPNHAPPATEVVDPTASGGRRLLLHGAASSLRRDRALLSSAFRRGTVDIPADAPYRCEFYQRTETSCDYTGPLVGVECALQPFPPAPPPPPSPPSPPDAPPARDVLLKVYGNGPGTASGGDLESNLCVPPAADAEDPQAAADEYDMCRSSTRADMLITEPASGQQAFAALCAIDDDYDLALLVANTLCKQMVDYPSSRYSSYGGTVLPSIPIPEADPPADALPPVFVPSAYADKWATIIGGEPNPRYPALQQMDFTVGSSCASGRLFAYKCTYRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WLG3</accession>
    <name>A0A835WLG3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_000028</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000012">
        <property type="protein sequence ID" value="KAG2449924.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WLG3"/>
    <dbReference type="OrthoDB" id="543991at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="300"/>
            <end position="332"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="70"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="87"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="300"/>
            <end position="320"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449924.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="678" mass="71214" checksum="DDCA197AFC1B0EDD" modified="2021-09-29" version="1">MRNLWRRWYNKNAATSWPAGQVPSLKAVLRQSKGLRPIDGLKEYFREYRKKRKQQGGQALTANDDAPSSRRARPAKRRRARSSRDDSSDEDEMEAELSVCSDEDAEAQVCSEDGEACEAAADCQDGAAVASSDEPSCAAAPAVEAASEPVAAESALPAAPMLLPGGWLAGPSAAAEVAAAGPSAELALQSLMFPTSEQVGFPQPAFAPQLQQLESPFMPMSAMPPLSMPKNAVHPAVAVGMVPLTGADCSNSSSPSLVDGPSPDLFDSLPNAPFVVLPAVPVRRGPPRLTARTRRAAAATLPPLTASSSSPVADQQQQAQSEEEHAADRCSAGGCMPPPNGRAFHHQGFDGFYPPYGPPMPYSAYPQPVCTCYPPRPVYPTFRAHSADCSSGGAASSGCCGPMPPQCFPPPHNQHQPAWGWYGPEPSCPYPCCAAPPPPCTIAGCRCGSPMPSPPHVQYAAWQGPHNAPASSEPWEAAASPAAQHGGIEHASDLEVCSSRGPEHGDLHKHQQHNAAVMVMMHHGRHAPSAYPHHHHPHPHAVSCPPWSRHSLPTSAPVPCGMVTVGSTNSVASLEVESGFVGAPSAEPCRLQRTSWPLAHDQQQPHAPASMASGAPEAAVALGKCAAATALDDEMALPRLDSLGAAGREGLDHELGMAWESFLNDGTDAMVDNVLVDV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WLG8</accession>
    <name>A0A835WLG8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">SRCR domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_005567</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449419.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WLG8"/>
    <dbReference type="OrthoDB" id="535306at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016020">
        <property type="term" value="C:membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.250.10">
        <property type="entry name" value="SRCR-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001190">
        <property type="entry name" value="SRCR"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036772">
        <property type="entry name" value="SRCR-like_dom_sf"/>
    </dbReference>
    <dbReference type="SMART" id="SM00202">
        <property type="entry name" value="SR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50287">
        <property type="entry name" value="SRCR_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-1015">Disulfide bond</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3" id="KW-0732">Signal</keyword>
    <feature type="signal peptide" evidence="3">
        <location>
            <begin position="1"/>
            <end position="23"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5033049154" description="SRCR domain-containing protein" evidence="3">
        <location>
            <begin position="24"/>
            <end position="461"/>
        </location>
    </feature>
    <feature type="domain" description="SRCR" evidence="4">
        <location>
            <begin position="99"/>
            <end position="152"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="28"/>
            <end position="108"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="266"/>
            <end position="289"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="2">
        <location>
            <begin position="267"/>
            <end position="285"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023157"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50287"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2449419.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="461" mass="49174" checksum="65BC299C148ECA90" modified="2021-09-29" version="1">MRRELSCTVVVAFLLVMDQVAEARPRSALLPPGKLDTSRKYSPPRRAPPPAKATVPSPKTISPSPLVAPVSLSPVPLPSPRAQPSQSGPPLAPREGNGIRLVGGSGSRGRLEVSSLDGWLNEYEEGAVAWRPVCNMVGFDDNDAQVMCELLGYTYGRLYYSDEVVRRAPNDTATDIDMPIENLDCSPNHAPPATEVVDPTASGGRRLLLHGAASSLRRDRALLSSAFRRGTVDIPADAPYRCEFYQRTETSCDYTGPLVGVECALQPFPPAPPPPPSPPSPPDAPPARDVLLKVYGNGPGTASGGDLESNLCVPPAADAEDPQAAADEYDMCRSSTRADMLITEPASGQQAFAALCAIDDDYDLALLVANTLCKQMVDYPSSRYSSYGGTVLPSIPIPEADPPADALPPVFVPSAYADKWATIIGGEPNPRYPALQQMDFTVGSSCASGRLFAYKCTYRSR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WMG7</accession>
    <name>A0A835WMG7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">C2 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005186</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449656.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WMG7"/>
    <dbReference type="OrthoDB" id="541621at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="CDD" id="cd00030">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.60.40.150">
        <property type="entry name" value="C2 domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044511">
        <property type="entry name" value="At1g03370/At5g50170-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000008">
        <property type="entry name" value="C2_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035892">
        <property type="entry name" value="C2_domain_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46296">
        <property type="entry name" value="BNAA05G37250D PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46296:SF8">
        <property type="entry name" value="OS06G0297800 PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00168">
        <property type="entry name" value="C2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF49562">
        <property type="entry name" value="C2 domain (Calcium/lipid-binding domain, CaLB)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="C2" evidence="1">
        <location>
            <begin position="6"/>
            <end position="63"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="Pfam" id="PF00168"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449656.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="137" mass="15236" checksum="E50B953DF704ABA7" modified="2021-09-29" version="1">MPHAEAETRVLMRNSHPLFEESLPFALDNVTEDMLVALRVFDKDIGHFNSFCGLVSLPIKQVLSTITEMGEEVVYRMPLMDKSGTSRKPGVLVFGISILAKDQYNEMRKVISAIQDPDQSLVALRAGEARDSGSVRL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WMJ0</accession>
    <name>A0A835WMJ0_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_005215</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449686.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WMJ0"/>
    <dbReference type="OrthoDB" id="556122at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.5.190">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF58042">
        <property type="entry name" value="Outer membrane lipoprotein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="66"/>
            <end position="121"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2449686.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="273" mass="30303" checksum="2630AD223CFC0056" modified="2021-09-29" version="1">MHVRRQSHLRSLSRQCRGVAPARIVKRIRQPEPVAFQEDGKPGEVAFNKGINGINEGPLKDLYARMDGLVADNKKFKADIEELKADIEELKADKKELKADKKELKADNTKFKADIEELNARVDNLQPAGDLVLLNVCAQVLDGLLFAAYSRIPPVAKPKKTKVYYKSTCTLFVQLYKRLSSKGIEDSTLKALAGSSPVKDFCKGADALMDARNLSVHPPILEELDRLVKDALKLVTPEVKARSPTLSRACDVLEQYEAVIRPAINSALISSRK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WMK4</accession>
    <name>A0A835WMK4_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_005607</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000014">
        <property type="protein sequence ID" value="KAG2449460.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WMK4"/>
    <dbReference type="OrthoDB" id="297739at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0732">Signal</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="signal peptide" evidence="2">
        <location>
            <begin position="1"/>
            <end position="15"/>
        </location>
    </feature>
    <feature type="chain" id="PRO_5032809494" evidence="2">
        <location>
            <begin position="16"/>
            <end position="556"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="62"/>
            <end position="82"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="SignalP"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2449460.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="556" mass="55883" checksum="55A146D8DBC89A8A" modified="2021-09-29" version="1">MFFLPVLLVLHCAFGLWMHTYFKAELSSMDLVGAASSAVGNAGINDLTDSGVGARITQPNGLALLIWFIALAAWLLFGRWVIWGTLKLLGNGCVRLASCLRIFAKDEEGVAITYEEALNATRVMDQLRGAATYRIHHLAGYKEYLSGDAAGKLWRAAQGKELYTRLMTFRCHVTLEEKDDDGATRYREQEVTMFDVKGDVIRAAPKLDLSTPAETLQPAVPSAALQNTVIQQLGGLAAQGTIIKSLSLQPSQVTSLVLPTQNPTYVMVDDGQVLPAAMAVAATAQLGNLGTVHEEQHGPAATTSAPAADPRFAGYAAATGVPTAVSAPMPVAATRVAGTAAAGTAAAAGTPAAAGTAAATKTAAAAGTAAAVGATAALGATAAAVGVTAAAGEDGKGRSSGNGNGKALEADDVKLSVGEEAAAAAAAAPPLYPSVPAGNQLAVTDSLQAVIAPHDSATYPGVAAVGQQPPHPGAGATLPYPTSPYPAAAVSAPSAPHMPPYAPEAPAGAYPAVPAWGGAEAAAAAAAAPGAYPPVSAGASAAYMAAEEARRQAQGQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-06-18" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WNI2</accession>
    <name>A0A835WNI2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Cas12f1-like TNB domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_004215</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000009">
        <property type="protein sequence ID" value="KAG2450942.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WNI2"/>
    <dbReference type="OrthoDB" id="541916at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR010095">
        <property type="entry name" value="Cas12f1-like_TNB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051399">
        <property type="entry name" value="RNA-guided_DNA_endo/Transpos"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30405:SF11">
        <property type="entry name" value="RNA-GUIDED DNA ENDONUCLEASE RV2885C-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR30405">
        <property type="entry name" value="TRANSPOSASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07282">
        <property type="entry name" value="Cas12f1-like_TNB"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Cas12f1-like TNB" evidence="3">
        <location>
            <begin position="38"/>
            <end position="96"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="110"/>
            <end position="164"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="118"/>
            <end position="148"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="Pfam" id="PF07282"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2450942.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="187" mass="18752" checksum="875A62032C89F533" modified="2021-09-29" version="1">MQVSIGYNNASTGHNSTTIKRPSRGPHKAMQRLLRRCYARSVTMIDKYCASQVCFNCGLRALRKILPHNGTRRYTVLACNGCGTVWNHDANAAANIRLITACLEEGLPRPAALEPPSRGGGGGQQHGGGDGGAGGGDAGGGAGDVGEGGGHRRAPSTRAATRAAAAAATSAAAAANAAAVQGGGAYG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WNL7</accession>
    <name>A0A835WNL7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">LisH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_004642</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000010">
        <property type="protein sequence ID" value="KAG2450805.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WNL7"/>
    <dbReference type="OrthoDB" id="437790at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036064">
        <property type="term" value="C:ciliary basal body"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005576">
        <property type="term" value="C:extracellular region"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="GOC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0060287">
        <property type="term" value="P:epithelial cilium movement involved in determination of left/right asymmetry"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006594">
        <property type="entry name" value="LisH"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR055289">
        <property type="entry name" value="OFD1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39063:SF1">
        <property type="entry name" value="OFD1 CENTRIOLE AND CENTRIOLAR SATELLITE PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR39063">
        <property type="entry name" value="ORAL-FACIAL-DIGITAL SYNDROME 1 PROTEIN HOMOLOG"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16045">
        <property type="entry name" value="LisH_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00667">
        <property type="entry name" value="LisH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50896">
        <property type="entry name" value="LISH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="585"/>
            <end position="614"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="711"/>
            <end position="739"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="188"/>
            <end position="520"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="549"/>
            <end position="583"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2450805.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="739" mass="81405" checksum="70C74DC5861B19F4" modified="2021-09-29" version="1">MSEPADAQEGLDQAAFNKKMLTHMQSTGVVGQVKSQLRAQLLTQLQKGQIVQLGPPPGDRPGLKRHALNSMIADYMRAVQYNYSLSVFKEESGVESRPLLTEDELMDVLKIDRETSFFQSYMKSKAHGGSDSCVLMNLVSAISEAAAAKGKESFTQTIGGDRYQLEVRMKQLEDEYQARLRNARLSPNAGVEERLAIYRQEVEEQAAAEVARQVERVREMEVAAARLDEASKARRALEAERLELDRLHSERLTKLRQREEEMMDKLRRQQRDVENVAYEYRQRILREEERLRNHKTEIQQQQDSRQEQLKQLERSLELRERAVGAREAAAEKKIAEATEAAAQAAVDARQDAEREYMELKSSLAQQRMQIEMDRSRILELRSEATAEIAAARAKEERLRALETARAEAEARAAAHAADAEVCRLQAEKLAAELAQTRDELSRRLAQASDGADAMLQNAAGAMNMLNAEAAASRTAGQQIRDALAALKRAEDEAAASAAAVASLQQERAALQNALAAAGAEGDALRTQLGRVEALMDEAVAGRAEALSHLEEAQFRHFQMERELAELRQALGRSKEEVAALKMANTVRRPPSRGADSPGRRSITLSPTRRPAPGAATTISALSLGLALGSGQGGALGQGTTGNGGASGYYWHSSQSGGGASGHHHHQSATQMEFPIAAAPPRDATLERMDRLRRQEDMLAGQEEAFRKRLAGVQDWPEYDLGSGPGSPEQPWPMDTTYMG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WPP0</accession>
    <name>A0A835WPP0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="12">Methionine synthase reductase</fullName>
            <ecNumber evidence="11">1.16.1.8</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="16" type="ORF">HYH02_003922</name>
    </gene>
    <organism evidence="16 17">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="16" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="16">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="cofactor">
        <cofactor evidence="2">
            <name>FAD</name>
            <dbReference type="ChEBI" id="CHEBI:57692"/>
        </cofactor>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="caution">
        <text evidence="16">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.16.1.8" evidence="11"/>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451316.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="1856718at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005829">
        <property type="term" value="C:cytosol"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0030586">
        <property type="term" value="F:[methionine synthase] reductase (NADPH) activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010181">
        <property type="term" value="F:FMN binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004497">
        <property type="term" value="F:monooxygenase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016705">
        <property type="term" value="F:oxidoreductase activity, acting on paired donors, with incorporation or reduction of molecular oxygen"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050667">
        <property type="term" value="P:homocysteine metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009086">
        <property type="term" value="P:methionine biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.80:FF:000001">
        <property type="entry name" value="NADPH--cytochrome P450 reductase 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="1.20.990.10:FF:000002">
        <property type="entry name" value="Nitric oxide synthase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.360">
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.990.10">
        <property type="entry name" value="NADPH-cytochrome p450 Reductase, Chain A, domain 3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.80">
        <property type="entry name" value="Nucleotide-binding domain of ferredoxin-NADP reductase (FNR) module"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.30.10">
        <property type="entry name" value="Translation factors"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR003097">
        <property type="entry name" value="CysJ-like_FAD-binding"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017927">
        <property type="entry name" value="FAD-bd_FR_type"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001094">
        <property type="entry name" value="Flavdoxin-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008254">
        <property type="entry name" value="Flavodoxin/NO_synth"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001709">
        <property type="entry name" value="Flavoprot_Pyr_Nucl_cyt_Rdtase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029039">
        <property type="entry name" value="Flavoprotein-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR039261">
        <property type="entry name" value="FNR_nucleotide-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023173">
        <property type="entry name" value="NADPH_Cyt_P450_Rdtase_alpha"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001433">
        <property type="entry name" value="OxRdtase_FAD/NAD-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017938">
        <property type="entry name" value="Riboflavin_synthase-like_b-brl"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384:SF84">
        <property type="entry name" value="METHIONINE SYNTHASE REDUCTASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR19384">
        <property type="entry name" value="NITRIC OXIDE SYNTHASE-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00667">
        <property type="entry name" value="FAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00258">
        <property type="entry name" value="Flavodoxin_1"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00175">
        <property type="entry name" value="NAD_binding_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00369">
        <property type="entry name" value="FLAVODOXIN"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00371">
        <property type="entry name" value="FPNCR"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52343">
        <property type="entry name" value="Ferredoxin reductase-like, C-terminal NADP-linked domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52218">
        <property type="entry name" value="Flavoproteins"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF63380">
        <property type="entry name" value="Riboflavin synthase domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51384">
        <property type="entry name" value="FAD_FR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50902">
        <property type="entry name" value="FLAVODOXIN_LIKE"/>
        <property type="match status" value="3"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-0028">Amino-acid biosynthesis</keyword>
    <keyword evidence="7" id="KW-0274">FAD</keyword>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="10" id="KW-0486">Methionine biosynthesis</keyword>
    <keyword evidence="8" id="KW-0521">NADP</keyword>
    <keyword evidence="9" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="17" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0949">S-adenosyl-L-methionine</keyword>
    <feature type="domain" description="Flavodoxin-like" evidence="14">
        <location>
            <begin position="114"/>
            <end position="257"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="14">
        <location>
            <begin position="417"/>
            <end position="560"/>
        </location>
    </feature>
    <feature type="domain" description="Flavodoxin-like" evidence="14">
        <location>
            <begin position="713"/>
            <end position="856"/>
        </location>
    </feature>
    <feature type="domain" description="FAD-binding FR-type" evidence="15">
        <location>
            <begin position="1317"/>
            <end position="1591"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="30"/>
            <end position="57"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="288"/>
            <end position="308"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="317"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="571"/>
            <end position="623"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="684"/>
            <end position="711"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="962"/>
            <end position="1204"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="1393"/>
            <end position="1420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="38"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="686"/>
            <end position="700"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="13">
        <location>
            <begin position="701"/>
            <end position="710"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="962"/>
            <end position="1026"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1027"/>
            <end position="1053"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1061"/>
            <end position="1073"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="13">
        <location>
            <begin position="1117"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1186"/>
            <end position="1202"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="13">
        <location>
            <begin position="1411"/>
            <end position="1420"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00001974"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022605"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022691"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022827"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00023167"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00039088"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00040659"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="PROSITE" id="PS50902"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="15">
        <source>
            <dbReference type="PROSITE" id="PS51384"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="EMBL" id="KAG2451316.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="17">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1749" mass="180035" checksum="1CF340C400971D2C" modified="2021-09-29" version="1">MVNTGVAVAGGLGALLLLTPLATFFLAASAQKRKKPRKDGEKAERKPDGKKSDDKALSVGASAAAAAPTNATAAAPAAAVATGGNAILARLKQQRAAPPAPAPAAAAVGAKPSLTFAFASQTGTGAEIARNLAAEAVEKGYKAQCMSLTELGYAALTSGRTPYLVIVASSTGDGDPPDNGGAFFVALRKKQEGKPLVGVKFTLLGLGDSNYTRFMYVPRAIKGRLLELGATEFYSCAEADEVEGIESVVDPWSEGLWAALEAEALAAATQQQAPVPLAAPATSESSAVAPASAPASTTAGSAPAPTGGNAILARLRQQRAAPADASTAQAPMAPPAADATSAAPAAAVADAGVVVKVATSVAPTAKQEPAPSASAAAAPAAAVATGGNAILARLKQQRAAPPAPAPAAAAVGAKPPLTFAFASQTGTGAEIARNLAAEAVEKGYKAQCMSLTELGYAALTSGRTPYLVIVASSTGDGDPPDNSGAFFVALRKKQEGKPLVGVKFTLLGLGDSNYTRFMYVPRAIKGRLLELGATEFYSCAEADEVEGIESVVDPWSEGLWAALEADIAPPKDQAAEQPPVAVMTAPSGPSRKSVEMMRGMSRTPVPAASAMPSKPSTPGPQTPVAATAPTLVDAPSRSLVPETSANGAVPKVEVGVAPVPATGGAALLAKMRSGGQQHTDTAVTTAPETAAKQQDAAAKPAQPPAEPAKPPVVAFTYGSQTGTGEEIARNLAAEAIQKGYKATCAPLNELGYAALTSGRTPVLVVIASSTGDGDPPDNAANFFVALRKKQEGKPLAGVKFTLLGLGDSNYTTFMGAPRAIKSKLAELGATEFHPCAEADEVDGIESVVDPWSEGLWAALKAATAVDQDAVAAVSIDGPAATAAVKPVAAKAGPSASEIAAAAAAAATAAEAAAKAAVEKEAAEKAAKEAAEKAAKEAAEKEAAEKAAKEAAAAAEKAAKEAAEKAAKEAAEKEAAEQAAREAVEKEAAEKAAKEAAEKAAKEAAEKAAAEKEAAEKAAKEAAEKAAAEAATRAAADATTAEEAAAAATNSAAAEAEELAEAEASAEALAAAAAHQHERPSSTATSDDGGSLLPSALLSVMEAGTASGANDHGLPTIKESRVFEEEPEPEAKEAAKGKGLAVLPESAGTEGGEDPLLSPRETEDGGDDMLLTPRGSVRGGGGRPDSRGSVASSTATGATGTWRRSVDLKSKTHLVAEAARRRSLEKPARLQAKPLNVNFPSREETVVKRKDEKAYGLLLGLAPVGVDTKGAPALLPCRLRLLWEKDEKRTDNILTKELLRPTREERHKLDPQGMYSPQQPFWAHISDARYETAFWSDRKVLHLELSIRGSNIAYSPGDAIGVLPTNHPDLVTNLCKRLNLNPDRVFYIAAPKDTSQGGAAPAEDLVSESGDAAPATPAGRPATHIPSPCSIGYAFTNCVDLTSPARKSLLRLLAEHAHDASEKRTLLFLSAKGGKDAYAHEIAEHQPSVLDLLVRFPSVTPPLDALLDALPPLAPRMYSITSSRKDSAKGPNRLSVALSVVRFKTRYGTRLGVASAWLDRLASPWTTEGISNPTNPVWVPIFLRRSADFKPPADLASPLIMVGPGTGVAPFRGFLQERRALIRETKPECVGEAVLFFGCRREDEDYIFKEELELMKAEGTLSALHVAFSRAQEAKVYVQDLIKAQGEKVWGLLQAGGYLYVCGDGAAMAKDVHAALLGVAVTHGGLSEADAAAYLQNLTQERRYVRDVWS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="18" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WQS3</accession>
    <name>A0A835WQS3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="5">F-box domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_003404</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
            <location evidence="1">Cytoskeleton</location>
            <location evidence="1">Cilium axoneme</location>
        </subcellularLocation>
    </comment>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451623.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WQS3"/>
    <dbReference type="OrthoDB" id="529833at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005930">
        <property type="term" value="C:axoneme"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.80.10.10">
        <property type="entry name" value="Ribonuclease Inhibitor"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR032675">
        <property type="entry name" value="LRR_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF52047">
        <property type="entry name" value="RNI-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="26"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004430"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2451623.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="5">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="473" mass="51329" checksum="DEE7F48407E6235D" modified="2021-09-29" version="1">MDFAVPEPEVSALSEPEGEGNNKSSSNVDLADAFARLNFGTTTTRASSSGHEELERHLPDAAVRSIANYLVQGEPPGHALIHLLAFCGVCRQWRGVGREVNPGVCIGFDVLENTFCAQSSIQRFRRRTVAQKEDVFCAAAKLLIGYTEVCFSGEAVSDRLVEAVAQRVGAKLVKVKLHNTKQVTDAALCALVRSAPLLECFVAEDLDRVAGKFLVPLMEDCPSLTTAHVANIPSLNWALCKQSSAQWGRKCLTKLVVRTVGLDESFGGIIAKLGSLTDIELDGPAVNIKAGALHCPSLGRVSYLVGRKSDLDEALAALMSIKELKQLELIVRNFVLTADELRVIGMLPVADLRLDSYVYKQQPTLSRSSYSHVDNEGVKALVDGICTRWCSHNNADMCPMKLSLCGATALTHDAVSALLRLPVLTELDIGGCCRITAMDKMRLVAKVKAGREMLESGRRPQVRMNSRFPGLLL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WR43</accession>
    <name>A0A835WR43_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Glycosyl transferase CAP10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_003130</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the glycosyltransferase 90 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452096.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WR43"/>
    <dbReference type="OrthoDB" id="541052at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016740">
        <property type="term" value="F:transferase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006598">
        <property type="entry name" value="CAP10"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051091">
        <property type="entry name" value="O-Glucosyltr/Glycosyltrsf_90"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203">
        <property type="entry name" value="KDEL LYS-ASP-GLU-LEU CONTAINING - RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12203:SF35">
        <property type="entry name" value="PROTEIN O-GLUCOSYLTRANSFERASE 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF05686">
        <property type="entry name" value="Glyco_transf_90"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00672">
        <property type="entry name" value="CAP10"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Glycosyl transferase CAP10" evidence="3">
        <location>
            <begin position="63"/>
            <end position="309"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00010118"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM00672"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2452096.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="369" mass="42070" checksum="B359018256041ACD" modified="2021-09-29" version="1">MFHLFRKELTPDILLLVLVYNNTMYWLEGPEGPALREVPSIASPYKHMLHKYVTHALARGRLQLPNVLFIYNSFDNGNRLGKPTRNLTAPPFSLCKSRGWYEGDDLDILVPQMIAIPDALYHVPWHLKKDLAFFRGVPSCSRIWEQTYQREEACARMHLAYLSERDRRAGNATALDVGLADVYKVVGEKKSTPYELPTYGRVPLDTHAHYKWLLNLEGFVAAYRMGQLLSMNSLVLHQRSYFMEYFYRSLQPWVHYVPFWNATSTEGSGTVAGAGAAGGGGTTALPPPPPRMDDVYDVLEQVRRMDREQPAALQRIIANAQGVAKMLSKPMRLEYYKAALEGYKELFPDMDQFLELFVQSLRSKGSDIT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRQ3</accession>
    <name>A0A835WRQ3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">Protochlorophyllide reductase</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_002914</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the short-chain dehydrogenases/reductases (SDR) family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452682.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRQ3"/>
    <dbReference type="OrthoDB" id="544331at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002347">
        <property type="entry name" value="SDR_fam"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320:SF262">
        <property type="entry name" value="DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24320">
        <property type="entry name" value="RETINOL DEHYDROGENASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00106">
        <property type="entry name" value="adh_short"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="1"/>
            <end position="42"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="110"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="173"/>
            <end position="223"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="364"/>
            <end position="387"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="13"/>
            <end position="24"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="127"/>
            <end position="150"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="3">
        <location>
            <begin position="177"/>
            <end position="186"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="188"/>
            <end position="210"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00006484"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2452682.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="6">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="387" mass="39184" checksum="9A72A55D8190BBB3" modified="2021-09-29" version="1">MADAAAGAGSEPQDPPPPQDPLPLPRSQHQHPHHQQQQLPAVRDLRGRVALVTGATSGLGLEAAAALAARGATVLFGARNPHKAARVAAEIRARFPPGTDLDLVLPSPHWPHLHPAETDNVQVDDASVGSSERGSSRRAQPAASAAAAAATPPVLCVPPLDLADPASISRFAAALLGPPPPPPPSSTAPSNGAQAQQQQQQQAVPQASGGAASGGAGSRAWVPPAGDEKAAAAAAAAAAAGEGGVWQLPLHILINNAGTSLLPPGPRSGVTDWGVNGLAQVNYLGAYQLTRLLAPKLLQGVRAQAAAAAGPSTPLSRVAGRVVAVSSVTHRCYELPADPRLFLHSTSDMTYAWTKCANVRGGREAGVAGRGGGQGWRSEGRWGAGGR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRQ5</accession>
    <name>A0A835WRQ5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">J domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_002266</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452923.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRQ5"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005783">
        <property type="term" value="C:endoplasmic reticulum"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051787">
        <property type="term" value="F:misfolded protein binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0051087">
        <property type="term" value="F:protein-folding chaperone binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036503">
        <property type="term" value="P:ERAD pathway"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd06257">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.110">
        <property type="entry name" value="DnaJ domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001623">
        <property type="entry name" value="DnaJ_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018253">
        <property type="entry name" value="DnaJ_domain_CS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051948">
        <property type="entry name" value="Hsp70_co-chaperone_J-domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036869">
        <property type="entry name" value="J_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44360:SF1">
        <property type="entry name" value="DNAJ HOMOLOG SUBFAMILY B MEMBER 9"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00226">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00625">
        <property type="entry name" value="JDOMAIN"/>
    </dbReference>
    <dbReference type="SMART" id="SM00271">
        <property type="entry name" value="DnaJ"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF46565">
        <property type="entry name" value="Chaperone J-domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00636">
        <property type="entry name" value="DNAJ_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50076">
        <property type="entry name" value="DNAJ_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0143">Chaperone</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="J" evidence="3">
        <location>
            <begin position="93"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="25"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="9"/>
            <end position="25"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00023186"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50076"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2452923.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="305" mass="30706" checksum="008EBA4AA450B689" modified="2021-09-29" version="1">MRSSSGSSAAPRRPTAAATAATTPQQQAAYAATAAATLGGYGPVLRPHAAAARVAAAAAAPGGVQPGADAGAPGASASASNTAAAASGEAAADLYEVLGVSRGATDTQLRRAYRNLLTRAHPDKPGGDAAAFRAVQRAYDVLSDPDKRRVYDSTGVIQKSPDQEFLERFAGGAYDDPRQAAAAAATDGSTLGGGGFGGGGSMADQIIVRHRATDFQSHTAGFEAWLRSRGGGGGTAGRVYTAESVAEQFGVARHSYDPVLLPRRANVLQVVCRGGGGGQLGEALALQAAPLPAELEWGHVLVAMK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRQ6</accession>
    <name>A0A835WRQ6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">tRNA-dihydrouridine(47) synthase [NAD(P)(+)]</fullName>
            <ecNumber evidence="3">1.3.1.89</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="15" type="ORF">HYH02_003277</name>
    </gene>
    <organism evidence="15 16">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="15" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="15">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="catalytic activity">
        <reaction evidence="9">
            <text>5,6-dihydrouridine(47) in tRNA + NAD(+) = uridine(47) in tRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53364"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="9">
            <dbReference type="Rhea" id="RHEA:53366"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="12">
            <text>5,6-dihydrouridine(47) in tRNA + NADP(+) = uridine(47) in tRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:53360"/>
            <dbReference type="Rhea" id="RHEA-COMP:13539"/>
            <dbReference type="Rhea" id="RHEA-COMP:13540"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
            <dbReference type="EC" id="1.3.1.89"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="12">
            <dbReference type="Rhea" id="RHEA:53362"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="10">
            <text>a 5,6-dihydrouridine in mRNA + NAD(+) = a uridine in mRNA + NADH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69851"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57540"/>
            <dbReference type="ChEBI" id="CHEBI:57945"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="10">
            <dbReference type="Rhea" id="RHEA:69853"/>
        </physiologicalReaction>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="11">
            <text>a 5,6-dihydrouridine in mRNA + NADP(+) = a uridine in mRNA + NADPH + H(+)</text>
            <dbReference type="Rhea" id="RHEA:69855"/>
            <dbReference type="Rhea" id="RHEA-COMP:14658"/>
            <dbReference type="Rhea" id="RHEA-COMP:17789"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:57783"/>
            <dbReference type="ChEBI" id="CHEBI:58349"/>
            <dbReference type="ChEBI" id="CHEBI:65315"/>
            <dbReference type="ChEBI" id="CHEBI:74443"/>
        </reaction>
        <physiologicalReaction direction="right-to-left" evidence="11">
            <dbReference type="Rhea" id="RHEA:69857"/>
        </physiologicalReaction>
    </comment>
    <comment type="cofactor">
        <cofactor evidence="1">
            <name>FMN</name>
            <dbReference type="ChEBI" id="CHEBI:58210"/>
        </cofactor>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the Dus family. Dus3 subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="15">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="1.3.1.89" evidence="3"/>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452252.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRQ6"/>
    <dbReference type="OrthoDB" id="259935at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0050660">
        <property type="term" value="F:flavin adenine dinucleotide binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0102265">
        <property type="term" value="F:tRNA-dihydrouridine47 synthase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02801">
        <property type="entry name" value="DUS_like_FMN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.70">
        <property type="entry name" value="Aldolase class I"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013785">
        <property type="entry name" value="Aldolase_TIM"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035587">
        <property type="entry name" value="DUS-like_FMN-bd"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018517">
        <property type="entry name" value="tRNA_hU_synthase_CS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR45846:SF1">
        <property type="entry name" value="TRNA-DIHYDROURIDINE(47) SYNTHASE [NAD(P)(+)]-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01207">
        <property type="entry name" value="Dus"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51395">
        <property type="entry name" value="FMN-linked oxidoreductases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS01136">
        <property type="entry name" value="UPF0034"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="4" id="KW-0285">Flavoprotein</keyword>
    <keyword evidence="5" id="KW-0288">FMN</keyword>
    <keyword evidence="7" id="KW-0521">NADP</keyword>
    <keyword evidence="8" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="16" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="6" id="KW-0819">tRNA processing</keyword>
    <feature type="domain" description="DUS-like FMN-binding" evidence="14">
        <location>
            <begin position="39"/>
            <end position="220"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="13">
        <location>
            <begin position="314"/>
            <end position="343"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00001917"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00005451"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00012376"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022630"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022643"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00048266"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00048342"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00049447"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00049513"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="14">
        <source>
            <dbReference type="Pfam" id="PF01207"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="15">
        <source>
            <dbReference type="EMBL" id="KAG2452252.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="16">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="343" mass="37805" checksum="897DA9E5CE366EAB" modified="2021-09-29" version="1">MGACRGRFASRTPDGFQAISAGKYDYRGYAVPSKQYSVCGGYPDALARVGQLLSQECEAVDFMDINMGCPIDLVCDKNAGSALLRQPKRMEQIVRATATALGEVPLTFKTRKGFNDGEDVAHTFLHKAGEWGAAAVTLHGRTRQQRYSRLADWDYIAQVGRNCATTGLQLVGNGDVFSYTDWNAHMGESGGHLASLMIGRGALIKPWLFTEIKEQRHWDISAGERLDLYRQFAAAGLEHWGSDSRGVESTRRFLLEWLSFTHRYVPVGLIEVLPQAMNHRPPAYRGRNELESLLGSDDPQDWLRISEMLLGPPPAPISFAPKHKSNSYASPPGGASEADMARG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRS7</accession>
    <name>A0A835WRS7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Splicing factor 3B subunit 1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_002958</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the SF3B1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452727.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRS7"/>
    <dbReference type="OrthoDB" id="438939at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000245">
        <property type="term" value="P:spliceosomal complex assembly"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="FunFam" id="1.25.10.10:FF:000039">
        <property type="entry name" value="Splicing factor 3B subunit 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.10.10">
        <property type="entry name" value="Leucine-rich Repeat Variant"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011989">
        <property type="entry name" value="ARM-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR016024">
        <property type="entry name" value="ARM-type_fold"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015016">
        <property type="entry name" value="SF3b_su1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038737">
        <property type="entry name" value="SF3b_su1-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12097">
        <property type="entry name" value="SPLICING FACTOR 3B, SUBUNIT 1-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08920">
        <property type="entry name" value="SF3b1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48371">
        <property type="entry name" value="ARM repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="2" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0747">Spliceosome</keyword>
    <feature type="domain" description="Splicing factor 3B subunit 1" evidence="4">
        <location>
            <begin position="308"/>
            <end position="452"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="29"/>
            <end position="59"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="146"/>
            <end position="315"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="935"/>
            <end position="958"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="3">
        <location>
            <begin position="151"/>
            <end position="191"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="3">
        <location>
            <begin position="197"/>
            <end position="211"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="292"/>
            <end position="306"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005754"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF08920"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2452727.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="958" mass="103019" checksum="641D7BA8656E4EBC" modified="2021-09-29" version="1">MADDEQRAKGVPLTGVVYDQDLYGKSDRAGYRSELVEEEEDDQDYGGGSRAFGTAAAQARGTIPDEAAEDGPGGLGFEQPKSIYEREDDYRRRRLNRIISPDRNDAFAMGDKTPDARVRTYADIMREQQLQRELDNTMVNIAKKKKEEAEAAAAAAAAGKAAAGAPSGATTTSSMPAPAASAGEAAAAAAAGKRRNRWDQSEPAKKPRSEWDTDGVEATPGLGNRWDATPGAGLTEATPGANRWDATPGVGAADATPAAGRWDDKPAGGAAGGRRNRWDEPTPARPSETPAGGWGGETPAGAGAGAGTTKRSRWDQTPALGGGATPAVGVGVTPSFFSAATPAVGALGATPLLGMETPSLSALGAGGMGGAGNVPLTPEQYQEMRLQREMWERNRPLSDEELDAMLPGEKDGYKILAPPAGYKPVIDPARKLMATPTPLVGGTPLYAMPEDNPALKADLPIAPEGLPEMKPEDMQFFSKLLQDVDEAELSTEEAKERKIMKLLLKVKNGTPPQRKSALRTLTDKARELGAGPLFNAILPLLMQPTLEDQERHLLVKVIDRILYKLDELVRPYVHKILVVIEPLLIDEDYYARVEGREIIANLSKAAGLAQMIAAMRPDIDNIDEYVRNTTARAFSVVASALGIPALLPFLKAVCLSKKSWQARHTGIKIVQQIAILMGCAVLPHLRSMVDIVKHGLKDENQKVKTITALCLAALAEAATPYGIESFDDVLEPLWRGIRSLRGKVLAAFLKAIGHIIPLMDAEHAFYYTREVMVVLRREFATPDEEMKKIVLKVVKQCVGTEGVEPDYIRAEILPDFFKAFWNRRMALDRRNYKALVETTVALANKVGCSDIVSRVVEDLKDESEPYRRMVMETIDKVITELGAADIDARLEELLIDGILYAFQEQVADDSPVMLNGFGTAVNGLGKRARPYLPQVRGGAGAGRGGAAERGRGGAGPGG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRS8</accession>
    <name>A0A835WRS8_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Peroxin-7</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_003266</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000006">
        <property type="protein sequence ID" value="KAG2452239.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRS8"/>
    <dbReference type="OrthoDB" id="361494at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990234">
        <property type="term" value="C:transferase complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.130.10.10">
        <property type="entry name" value="YVTN repeat-like/Quinoprotein amine dehydrogenase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR015943">
        <property type="entry name" value="WD40/YVTN_repeat-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036322">
        <property type="entry name" value="WD40_repeat_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001680">
        <property type="entry name" value="WD40_rpt"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847:SF637">
        <property type="entry name" value="WD REPEAT DOMAIN 5B"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR22847">
        <property type="entry name" value="WD40 REPEAT PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00400">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="3"/>
    </dbReference>
    <dbReference type="SMART" id="SM00320">
        <property type="entry name" value="WD40"/>
        <property type="match status" value="6"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50978">
        <property type="entry name" value="WD40 repeat-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50082">
        <property type="entry name" value="WD_REPEATS_2"/>
        <property type="match status" value="2"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0677">Repeat</keyword>
    <keyword evidence="1 3" id="KW-0853">WD repeat</keyword>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="103"/>
            <end position="133"/>
        </location>
    </feature>
    <feature type="repeat" description="WD" evidence="3">
        <location>
            <begin position="205"/>
            <end position="225"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="56"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="246"/>
            <end position="288"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="422"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="579"/>
            <end position="620"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="706"/>
            <end position="733"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="757"/>
            <end position="817"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="4">
        <location>
            <begin position="979"/>
            <end position="1002"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="67"/>
            <end position="84"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="4">
        <location>
            <begin position="246"/>
            <end position="255"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="256"/>
            <end position="283"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="450"/>
            <end position="464"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="465"/>
            <end position="474"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="475"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="4">
        <location>
            <begin position="498"/>
            <end position="507"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="508"/>
            <end position="521"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="547"/>
            <end position="558"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="591"/>
            <end position="602"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="706"/>
            <end position="727"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="4">
        <location>
            <begin position="769"/>
            <end position="808"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="4">
        <location>
            <begin position="984"/>
            <end position="1002"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022574"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022737"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00221"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2452239.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="7">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="1002" mass="100938" checksum="BFB75FD3E930450A" modified="2021-09-29" version="1">MSACKYYRTELGEDSLWAPWHGLPQLRYHSSHSSYSTYARAVSAWLRPGQPPQYPRAHSIVSSGGCSSPSAAAPPATLQQQQQQQQQPSLLLPLLLPATGSIPAAHERWVTCVDLAPGHMLSGSMDANVKFWDRGRHGAWIHYLRGHTGPVSAVRFSYDTTGIAAGSGHAFGSGSNGYGGGFGPGAGGGLAAAVPAAVAPRSCFSGSRDGTLRVWDLATGTCVRAYTAEGGRQWVNTVAVWRPPQPALALSPPPASQQSDIDSSWHGFNSSSSSSSSSSSSSSFGGGSSTGAANPAATVVVGTSVGQLCLYDVRQAGPAARLWGIQEVQQGAVYGTSVYGDALAAACANGCIYVWDLRRTGGGSGGGTAAAAVRHVLDEHGSACTTVALHGPTLVAGDLEGGLYVWSADTAAADHRPRLRGALPAASSNSSSRSHSRRQLPSDWQQHQPGAAPVPAVASAAAWRRGGGGGGGLGKWSSGAAAEAAAGPGPGEGWPRWGRYRRRHRRMGGGGRAKPGAGAGGAHDSSSSSEAGDEEDQEEDQGRRHGSSSCGGSSRARGAAGCSEAGVVVSILQVLAAAGGGGSQPWPLPRQQQQQQQQQQQQRAQHLRGSQHAWQRPLAQSPWLDDDWQLGIAGGGSRADAAAATAVVAAELAAARLDGAAAGAGAGDREAASACALLLSSASLGSPASAASAAASLSASSSLMMGLSPASSMSHSSSHASSTSSGFALGGGGGGAAVAPTATACGGSARSLLLSTGGGGGAGAPAPAPAYSSSLPHTPRSAQTTQQQQQQQQQQQQRLQEACAAQRQLDQRRPRPAPRLLATARHGEWVRDVALLGPLLAVSAAKDGRVALSRLDTMQVVAAWDLSAPGDGTAWYLNSNSSSSCSSQQAGAAAHAASPLAADSFSFAPAPASRLGSGGGPAPSRPAVAAVAAHNCTGYGHNQVHALAADVWGFVAGCQDTSLRLWSFVPPPPAFAAATTAGSGADGGGGEPWGGGSLPELV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WRU6</accession>
    <name>A0A835WRU6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_002335</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452999.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WRU6"/>
    <dbReference type="OrthoDB" id="529589at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2452999.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="354" mass="37430" checksum="264825B97AFE70F3" modified="2021-09-29" version="1">MTKAKVKELQDHAHFYGAAEALTRWTESVFALSALAHAALAKQPDGAAGSACVHDGKRCLMNPAVVSGAGFPAPQLPAEKIIQRFAKEAFVCRGSADRATCHLDSNCDWDDRTGACFLAHDPHSDFTNVIAMCQGTIYTPAAKACWRRRPDSSAWRPCGETGCTLFAKGSEVGPGTTTAADRCLPAAPGNMQQKDLYNMLKRLYGETYGMDELPVATIVTLANGTQVVTMAPAAGAAGFGAAALQEGHEFAKEGFGSCDTAALHHGFATSCRHAEEQEACEKDNRCRWLEDGVRGSHCVLTRHTVVQLLLGGSAFTQAALQAEAACTAAAGSRDACLAVKHVQQQQQQQSGGSS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WS46</accession>
    <name>A0A835WS46_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_002274</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452937.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="248495at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.450.40">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029016">
        <property type="entry name" value="GAF-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008266">
        <property type="entry name" value="Tyr_kinase_AS"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55781">
        <property type="entry name" value="GAF domain-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS51257">
        <property type="entry name" value="PROKAR_LIPOPROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00109">
        <property type="entry name" value="PROTEIN_KINASE_TYR"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Protein kinase" evidence="3">
        <location>
            <begin position="1067"/>
            <end position="1349"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="38"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="133"/>
            <end position="352"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="749"/>
            <end position="804"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="955"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1107"/>
            <end position="1135"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="485"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="63"/>
            <end position="76"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="93"/>
            <end position="119"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="2">
        <location>
            <begin position="144"/>
            <end position="155"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="156"/>
            <end position="165"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="189"/>
            <end position="206"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="211"/>
            <end position="222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="224"/>
            <end position="240"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="2">
        <location>
            <begin position="321"/>
            <end position="336"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="338"/>
            <end position="347"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="749"/>
            <end position="764"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="772"/>
            <end position="782"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="2">
        <location>
            <begin position="1115"/>
            <end position="1128"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2452937.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1351" mass="137741" checksum="EB2AA2F439B2EC16" modified="2021-09-29" version="1">MAPVRSVGDLTAFTAASGGGAGSCVDPASLPPVKVETTRRHNAGTEGSNSAGYSASATSSLQQGGGGSSAAQGAGGSSAAHGGAGSSAMGPTPGSSAAGPTLGSSAAGPAAGSSAADSTATADGAASKAAGGFMFGAPRMKEHKEKRRKEAKRAKSQSSSNASSNPKHILGSEGQPPTEGSKGQSIGAGSSGPGPTAGAGTSGGGVLPIVGSSSMVPPNGSSAMMPSNGSSDNMMSSSTNLQADMASPTVGSTAGNTVMLEGSSGANPVANFKSIGRSRAPRTAAGSKTPGEGSSGRGSSVPTPGSGLAAPVEGAPPPVPEGEEEGESQGEGDDDSSSPRSSSDHLSIMSPPEGSDVENVLQLICNIFQLPVALVAAYRSANIFIRSTALKLTDDDQWRYSLAQWSMLNVHDLRDVLVVPDATLDDRFRNQYCVANEPRLRFFCASPLRSSTGELLGTLCMADFKERIFEPTNLLVVNNLQSLVIRQLERDMALAAERLENEVATEQLQQEMMRALDHFEKCIMFVDTSKPGWEVLYTNLAWEHVTGIPREHVLGPVLNPSVPRVHVLGRSLQDFFMALGGASLDWSSTAAELASRSEFTVNRVAVRQKPDKLVSLHLRLATNQANGELEGLLPKGLPAWVKARGSEAHNYFVFVEEAQGGSTVYEALAKHVEKVPGLELSHLLGKGGFGSVYYGTWNGLPVAVKMIDNRLTKTNTEGVSLEALMGQELAHPNIVKTIKYVMRNQLNASSVSGSNSRGPGSSHQRPGRSGQPPGSQLNSRNPHVTPPVGSRHGSRNPPHGTDPAMNAAAAALVNARGATGATSANPGMMQYLTSANPGTGPMTSAQIAAAADLTSASGMNINNMQLQHMVSTMTSDATTVAGGGTDTIGSSGMPGRAANLVGSMSAGTGHGSTPLTHNPAGVAAAAAAAAAAANAAELARHVAATATAAAAAGQPGGKAAAADGDESTTTASGVTAVGPASVHASSASTAAGPPSIVSAGVPANPVSPANLSHSASATALHAKVGSSGRTPTSAQRTAAAAAIAAAPPLPAVLPPLAAAAANPAATTSITAAYPPGAPPPNLTTEQQHAAMTSRFSMAFSTITEGGDVLVPEKGSPSTSTDSHTQRPNVGSAGSGEDMGEVWIIMEFCDRGSLQDALDRGALKLRKPSGEMGETHLPMMVATACEVASALQYLHDRGIVHGDLTAWNVMLCTAADPAADRSGRNFTAKVADFGLSRNLDVRSKIKTRTYGTISHMPPECLISGIISKATDVFAFGVLLWQMYTGLRPWAGMNHGQIIYNVGMKNVQLLFPPGTPPAIADLSSSCTRTDPNTRPSFGEIMEKLGNIRASLGL</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WS49</accession>
    <name>A0A835WS49_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_003387</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451605.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WS49"/>
    <dbReference type="OrthoDB" id="553346at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="314"/>
            <end position="348"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="468"/>
            <end position="502"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="538"/>
            <end position="640"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="756"/>
            <end position="783"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1"/>
            <end position="20"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2451605.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="922" mass="97672" checksum="4CACD49E1766B327" modified="2021-09-29" version="1">MLPVAESASSTASSVSSFDSSPRHHHGMYGGVPHDTTTTSGEAGAPASLVSGMAWIGASVSRAAAGWQVTHNPVFEDDDGATQTAMTPLLAPSARHSLPGTAATVHLTSSPLPEALAAYAAAGVDAASAAPVRKSISASVGLPLSPAPQQRTEATGCVGAGDVLAAGGYMQGSSPQQGIGHFGRMLGPAGVSPSFADQVAATTAVSRAIRKLLKLARENSGLTRSNEQLRGELSRVQTTQLEVQARNKLLQAMLEERGNEVARLSKANLRRTVKLESQLTGCQERIRQLESMQAQLVLEGHQQVQQLEEAYGHVASISTEAASLRQEVKQYAEACAAHQERVAMLEHELAGAAAAAEQEASAAEAVEAAAAAMAAEAHEQHHNRLRLLQVLLANDELEPYQLAWTYSDWGSHAGNGAQLLPPAAECSSTVPLQQTAGGSYDRSNAGQQKQLLDSQQLQQLVCDLQHQLAGAQELHAQLQDELEAARVAMAELVAERLAARAEMARWEVAAAQSAAVAAAAQAAEVQAREGERRAQQAVGQCEAQMREVMSQLRAAQQQFAEREESLQQLLVQAEAEHEVLRRQGQQEVEGMQQQLAHAEAECDALRQQAQQELHTWEQQLAEAQANAAQLEHVVQEHKQMQLREDDDATLVTLQHELVSQLQQQLFEERQRSAVLGVEVQTATRRLLDFKQQLRAVSIANAGEPAAGPVCWDNATGTAMEDLTATATITPHSAAGSGGSPPVLEIAGALVRVHAELHDLRGRQADAEELIALQEQELKALRGEHGGSGAVIDVNVCPGSLAVTPSSSLVHEPWAGASSHAMPAMSSLLRGGCSLSMAEPVLQLRYALRQVEQTSAELAGIMCGECDAGTSDGTSAPVLPPGAVTGIESGLQEQVWVIQNLRQLTAAARRVAAWLAACLPPHS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WS53</accession>
    <name>A0A835WS53_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_002702</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000005">
        <property type="protein sequence ID" value="KAG2452462.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WS53"/>
    <dbReference type="OrthoDB" id="637682at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.70.10">
        <property type="entry name" value="Transcription termination factor 3, mitochondrial"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038538">
        <property type="entry name" value="MTERF_sf"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="31"/>
            <end position="56"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="31"/>
            <end position="53"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2452462.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="173" mass="17970" checksum="A10CF924CF67206A" modified="2021-09-29" version="1">MLLHASIGYGLSEQEVWKVLAYGSNSNNNNNDVAAASSPSSSSSSSPSSSTASFDGLSAGGNTTSGLVGAPGASPYAAGAAIVWFKSWGWSDADVAGRLLPCYPHVLAGGPEPLQAAVERLRQHSFADEDIRRMVLTFPALLSPPLSAPLLELIGRIRASAHNKYVVSGSYHV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WT58</accession>
    <name>A0A835WT58_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_002486</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453161.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="552633at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050972">
        <property type="entry name" value="SDr-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34403:SF16">
        <property type="entry name" value="GLYCINE, ALANINE AND ASPARAGINE-RICH PROTEIN-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR34403">
        <property type="entry name" value="TOL-PAL SYSTEM PROTEIN TOLA"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="73"/>
            <end position="126"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="406"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="594"/>
            <end position="615"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="711"/>
            <end position="1147"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1173"/>
            <end position="1214"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="2">
        <location>
            <begin position="1228"/>
            <end position="1319"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="146"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="490"/>
            <end position="523"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="594"/>
            <end position="609"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="711"/>
            <end position="721"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="729"/>
            <end position="779"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="2">
        <location>
            <begin position="788"/>
            <end position="1012"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1073"/>
            <end position="1106"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1113"/>
            <end position="1132"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="2">
        <location>
            <begin position="1174"/>
            <end position="1190"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1228"/>
            <end position="1241"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1267"/>
            <end position="1278"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="2">
        <location>
            <begin position="1286"/>
            <end position="1299"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2453161.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1334" mass="128713" checksum="CFF5F145C9E684BE" modified="2021-09-29" version="1">MFGGRRRKEEADAKEREVQFWKSELDKVVEEKNGWIDKFVKAADDADMLRAELFLVQREAATSRAQLEVYRKQEECRGRSDGSTAGTPGRGVLAPSVAGSRGPSQTSTPVKSAPVPVQQAVPMSPSGAQSVTGVRAAAVAAADDLVAGLRAEVGRLRRQVEAAELASHQADMRTAILEERLAEAARELDAARRQTEFMRTTAEAHQREADALRAEVLSQRFINDETANETTKILSELSAAQQRCAKLAAELSSKEQMVGLLQLQLGDMAAAAAASTGGGVPSSLSGMTSAAAGATAAAGAPAAAASAASVATTAAAAAFGISAAPAPAPAAAASASANSGPPGGSVSLSASGLGLAATIAANAGGGKPSPATVASSSAFSTAGTGPVFGGGVASGILGRGMERYGSGGGGAASGGSEWPSARQLESPLDGGKSPVFGQTSGGESGSGDATPGESSAQVTPMGRLWAAANAAAGSVSPSGTDVATPPPGTAGPSPALGGSARANGNSSSGAVSPSSDTSSASPPVASAAASAVTTAPGAAAVTIDADGGGAAPRAYQETAMQVELTPPAQPPSVLRKSLSKGFAAAAAAATGRPAAGDAAAGPVPGASSGRAHHRPPQVPHLPLATALRNGGAGSTAKAAAGAAVAGGGEASAVAHIGKRDPGQQPAPEAEDTPLAKKVVASGMGKVAAAAALFGGKAGAPPPAAADAEARAKAAAEARAKAEMGATAKAEAEAAAKAEAEARAEAEAKAKAEAEAEAKAEAEAKANADAEAKAKADAEAAKALAEAKAQAEAEAEAKAEAEAKAKAEAEAKAQAEAEAKAKAEAEAKAKAEAEAKAKAEAEAKAQAEAEAKAKADAEAKAQAEAEAKAKAEAEAKAKAEAEAKAKAEAEAKAKAEAEAKAKAVAEAKAKAEAEAKAKAEAEAEAKAKAEAEAKAKAEAEAKAKAEADAKAKAEAEAEAKAKAEAKAKAKAEAEAKAKAEAEAKSKAEAEVKAKAEAEADAKAEAEAKAKAEAEATAAKALAEAKAESSKSPPSGREAKGKGAAMDGDGLGSNVASPASSGGPIKVGRPGLVRAAAAAKKGAAAAAETSKSMESSEAGGSAAPSAGATPRTQESAAAAPAAPASAAASTAPPAASKPPQAPVPAAAQDEAGKVAGAIKGSTLSATAALLKRFNSGGLGAGAGQPSDGGSGPGSRARSPSPLTAGMGSEVGATSGSGLASVTAALRRLSGTGAAGSDATGTSTQPRSLQPTPPRLVPEGGVTGLLNKFNNATGGSSAGAVTGAGGSNSGSSAAGNAASSSTPVPTIPAPEYGFGGPASRVPASAKIAQMRSAFEKK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="17" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WT82</accession>
    <name>A0A835WT82_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="16">Calcium-transporting ATPase</fullName>
            <ecNumber evidence="16">7.2.2.10</ecNumber>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="19" type="ORF">HYH02_001989</name>
    </gene>
    <organism evidence="19 20">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="19" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="19">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="16">Catalyzes the hydrolysis of ATP coupled with the transport of calcium.</text>
    </comment>
    <comment type="catalytic activity">
        <reaction evidence="15 16">
            <text>Ca(2+)(in) + ATP + H2O = Ca(2+)(out) + ADP + phosphate + H(+)</text>
            <dbReference type="Rhea" id="RHEA:18105"/>
            <dbReference type="ChEBI" id="CHEBI:15377"/>
            <dbReference type="ChEBI" id="CHEBI:15378"/>
            <dbReference type="ChEBI" id="CHEBI:29108"/>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
            <dbReference type="ChEBI" id="CHEBI:43474"/>
            <dbReference type="ChEBI" id="CHEBI:456216"/>
            <dbReference type="EC" id="7.2.2.10"/>
        </reaction>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Endomembrane system</location>
            <topology evidence="1">Multi-pass membrane protein</topology>
        </subcellularLocation>
        <subcellularLocation>
            <location evidence="16">Membrane</location>
            <topology evidence="16">Multi-pass membrane protein</topology>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 16">Belongs to the cation transport ATPase (P-type) (TC 3.A.3) family. Type IIB subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="16">Lacks conserved residue(s) required for the propagation of feature annotation.</text>
    </comment>
    <comment type="caution">
        <text evidence="19">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EC" id="7.2.2.10" evidence="16"/>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453779.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WT82"/>
    <dbReference type="OrthoDB" id="3352408at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0012505">
        <property type="term" value="C:endomembrane system"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005886">
        <property type="term" value="C:plasma membrane"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016887">
        <property type="term" value="F:ATP hydrolysis activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0046872">
        <property type="term" value="F:metal ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005388">
        <property type="term" value="F:P-type calcium transporter activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-EC"/>
    </dbReference>
    <dbReference type="CDD" id="cd02081">
        <property type="entry name" value="P-type_ATPase_Ca_PMCA-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="2.70.150.10:FF:000029">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.1110.10:FF:000045">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000018">
        <property type="entry name" value="Calcium-transporting ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.40.50.1000:FF:000001">
        <property type="entry name" value="Phospholipid-transporting ATPase IC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.70.150.10">
        <property type="entry name" value="Calcium-transporting ATPase, cytoplasmic transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1110.10">
        <property type="entry name" value="Calcium-transporting ATPase, transmembrane domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1000">
        <property type="entry name" value="HAD superfamily/HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006068">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004014">
        <property type="entry name" value="ATPase_P-typ_cation-transptr_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023299">
        <property type="entry name" value="ATPase_P-typ_cyto_dom_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR018303">
        <property type="entry name" value="ATPase_P-typ_P_site"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023298">
        <property type="entry name" value="ATPase_P-typ_TM_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008250">
        <property type="entry name" value="ATPase_P-typ_transduc_dom_A_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR059000">
        <property type="entry name" value="ATPase_P-type_domA"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036412">
        <property type="entry name" value="HAD-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR023214">
        <property type="entry name" value="HAD_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR006408">
        <property type="entry name" value="P-type_ATPase_IIB"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001757">
        <property type="entry name" value="P_typ_ATPase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR044492">
        <property type="entry name" value="P_typ_ATPase_HD_dom"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01517">
        <property type="entry name" value="ATPase-IIB_Ca"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="NCBIfam" id="TIGR01494">
        <property type="entry name" value="ATPase_P-type"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093:SF369">
        <property type="entry name" value="CALCIUM-TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR24093">
        <property type="entry name" value="CATION TRANSPORTING ATPASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF13246">
        <property type="entry name" value="Cation_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00689">
        <property type="entry name" value="Cation_ATPase_C"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00690">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00122">
        <property type="entry name" value="E1-E2_ATPase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08282">
        <property type="entry name" value="Hydrolase_3"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00119">
        <property type="entry name" value="CATATPASE"/>
    </dbReference>
    <dbReference type="PRINTS" id="PR00120">
        <property type="entry name" value="HATPASE"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDG00002">
        <property type="entry name" value="C1.7:_P-type_atpase_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDS00003">
        <property type="entry name" value="Haloacid_Dehalogenase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SFLD" id="SFLDF00027">
        <property type="entry name" value="p-type_atpase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00831">
        <property type="entry name" value="Cation_ATPase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81653">
        <property type="entry name" value="Calcium ATPase, transduction domain A"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81665">
        <property type="entry name" value="Calcium ATPase, transmembrane domain M"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56784">
        <property type="entry name" value="HAD-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF81660">
        <property type="entry name" value="Metal cation-transporting ATPase, ATP-binding domain N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00154">
        <property type="entry name" value="ATPASE_E1_E2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="9 16" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="8 16" id="KW-0106">Calcium</keyword>
    <keyword evidence="4 16" id="KW-0109">Calcium transport</keyword>
    <keyword evidence="13 16" id="KW-0406">Ion transport</keyword>
    <keyword evidence="10" id="KW-0460">Magnesium</keyword>
    <keyword evidence="14 16" id="KW-0472">Membrane</keyword>
    <keyword evidence="6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="7 16" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="20" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="11" id="KW-1278">Translocase</keyword>
    <keyword evidence="5 16" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="12 16" id="KW-1133">Transmembrane helix</keyword>
    <keyword evidence="3 16" id="KW-0813">Transport</keyword>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="125"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="155"/>
            <end position="174"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="313"/>
            <end position="331"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="351"/>
            <end position="375"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="769"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="838"/>
            <end position="864"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="992"/>
            <end position="1011"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1031"/>
            <end position="1054"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="16">
        <location>
            <begin position="1066"/>
            <end position="1085"/>
        </location>
    </feature>
    <feature type="domain" description="Cation-transporting P-type ATPase N-terminal" evidence="18">
        <location>
            <begin position="54"/>
            <end position="141"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="17">
        <location>
            <begin position="1126"/>
            <end position="1159"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="17">
        <location>
            <begin position="1126"/>
            <end position="1143"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004127"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006124"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022448"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022568"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022692"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="ARBA" id="ARBA00022837"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="9">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="10">
        <source>
            <dbReference type="ARBA" id="ARBA00022842"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="11">
        <source>
            <dbReference type="ARBA" id="ARBA00022967"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="12">
        <source>
            <dbReference type="ARBA" id="ARBA00022989"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="13">
        <source>
            <dbReference type="ARBA" id="ARBA00023065"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="14">
        <source>
            <dbReference type="ARBA" id="ARBA00023136"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="15">
        <source>
            <dbReference type="ARBA" id="ARBA00048694"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="16">
        <source>
            <dbReference type="RuleBase" id="RU361146"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="17">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="18">
        <source>
            <dbReference type="SMART" id="SM00831"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="19">
        <source>
            <dbReference type="EMBL" id="KAG2453779.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="20">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1178" mass="126873" checksum="3F00F14492DB066B" modified="2021-09-29" version="1">MAKDKGNEGEGAPQASSINVAALEMDKDCPYSILPSILFQMNSDKDMERLHMFGGTAGLAKGLVTDLHTGLTESSAPAGDGLATAAASGLGSVDAHRTAYGENKFPEKPPPNFFMMLLEAAKDPMIIILLIVAIVTIVLGAAVPEQRAHKGWSEGLAVLGTALIVIFLGAGQDYSKERQFQKLNALKDVIDVKVTRGGKQVLVPNTEVVVGDVMFLDTGDKVIADGIVIDSQGLVLDEASLTGESDPIKKDPVSDPWVRSGTTVNEGSGHMLVLAVGAHSEWGKTMTLVSEAGDDQTPLQEQLTDVAAKVSKMGVLVAVVCFLALLIKWLIETGGGDVDKINNNGPLQFLLYAITITVVSIPEGLPLAVTLTLAYSMKKMMKDKNFVRVLSACETMGGATAICSDKTGTLTENRMTVVEGWFAGTAYPQVPEASALGPHVLELLKWNCSMNNKAFLVDQESGVTDFVGNRTECALLVMLRKLGLDYKQLREEREADQVKLYGFSSARKMASVLLRERATGNLRLYNKGAAEWVLKRCVGLARPDGSTEPMTHAKLEEMNALVTGMAKRGLRCICLSYRDYAGSDLSRPADFFEDADAVDRDLIAVAIVGIKDPVRKEVPDAVITCQKAGIVVRMVTGDNIHTAQHIARECGLLTDGDAIAMEGPVFRAMPAAELIPLLPRLRVLARSSPEDKLTLVSLLKKQGEVVAVTGDGTNDAPALKESDVGLAMGIAGTEVAKEAADIIILDDNFSSIVKSVLWGRAVYMNIRKFLVFQLSINLVAMISAAVGALYGGVPPLNVLQLLWVNMIMDTLAALALATENPYPELLDDKPHGRSEPIITGLMYTHIVVAAIYKLFWLFACLYGLPRVLPAYATLTKNEYYTTMCTKVLNGKNVLSADVALQNDVCNIMGFCGYPKGDIHSDLCVLHNEWLAVNTTVPSLQQDAVCNGQFNPTANYSGVVAPGEACARNNNLMSGQKAMDDEWDREYRLSYKPALSVLFNAFILAQVANAFVSRRIGLELNFFKGLSTSPIFNSIMVLITVLQVIIMQTPISYIFKVEPLNGPEWGACIAIGIGAIPFSWALRILLRWMLPLTANSSHWLAGLRGSRASNITASGAGPMRAAAHTRTLSGASGNHNNRTASGRTLSGPHGGGYQDTHHRTISGNPHVMVSTYLKEQQGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WT83</accession>
    <name>A0A835WT83_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_001522</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453295.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WT83"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="65"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="111"/>
            <end position="143"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="160"/>
            <end position="179"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="7"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="47"/>
            <end position="64"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="166"/>
            <end position="179"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2453295.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="335" mass="32473" checksum="7DA7FFEF5E88B398" modified="2021-09-29" version="1">MTLAAGAGAGAGAGAGAGAGAGAAPAGGAPGALQSVPVGAAVSTGWAARRSSNGSSSSSSAAEALRAHRPAQPLFLLADATASGRRGLQGGDAELDIAGAEAVLKEMMTGQRDLGGGSSSSSGNSRVGHGGGGSSSREALPSASRAVGWAADAAAAEGVGGGFVDGGDEDDEAAEAEAEAEQALGMVQCGFCGRRLGRRGVRSALLCDCCHRPFHADCCRYRGVPTRRRRLQAGEGAAGAGGGGGGGGPHADGWFHSPDCAAVSTQWFGRTAAGPQPAAAGRTWLLLPTQLRGGSASSSGGGSTSAEARNGLQQAAGVLAGEFGPRVVDAVLDRR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WU97</accession>
    <name>A0A835WU97_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_001131</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454092.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WU97"/>
    <dbReference type="OrthoDB" id="439808at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="CDD" id="cd21608">
        <property type="entry name" value="RRM2_NsCP33_like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="FunFam" id="3.30.70.330:FF:001150">
        <property type="entry name" value="RNP-1 like RNA-binding protein"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR048289">
        <property type="entry name" value="RRM2_NsCP33-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR052462">
        <property type="entry name" value="SLIRP/GR-RBP-like"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR48027">
        <property type="entry name" value="HETEROGENEOUS NUCLEAR RIBONUCLEOPROTEIN 87F-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00076">
        <property type="entry name" value="RRM_1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1 2" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="4">
        <location>
            <begin position="3"/>
            <end position="80"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="3">
        <location>
            <begin position="75"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="3">
        <location>
            <begin position="85"/>
            <end position="110"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2454092.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="149" mass="14734" checksum="863D1F4499C2CAD7" modified="2021-09-29" version="1">MSTKLYVGNLSWDTRADDLTNLFSKFGTVEDAFVATDRETGRSRGFGFVTLEANAAKSACSECDGTEFMGRTIRVNEATPLGERPPGGRGGGRGGYGGRGRGGDSYGGGYGGGRGGGYGGGYGGGRGGGGYGGGGYGGGGSGGYGEGYA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUW2</accession>
    <name>A0A835WUW2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="1">GCK domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_000575</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454738.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUW2"/>
    <dbReference type="OrthoDB" id="522768at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.287.2900">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012891">
        <property type="entry name" value="GCK_dom"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07802">
        <property type="entry name" value="GCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01227">
        <property type="entry name" value="GCK"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="GCK" evidence="1">
        <location>
            <begin position="8"/>
            <end position="78"/>
        </location>
    </feature>
    <evidence type="ECO:0000259" key="1">
        <source>
            <dbReference type="SMART" id="SM01227"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2454738.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="93" mass="10214" checksum="188D43687A4944F6" modified="2021-09-29" version="1">MEQAEGKKECPICVMFREGGCEKQFNAFMDCGVKGEKGDGDYKDCIPLFESMRQCMQRNPAVFGEVLNDVEELAKTNTEYPPAPPATATAAAQ</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="16" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUW4</accession>
    <name>A0A835WUW4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="13">Enoyl reductase (ER) domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="11" type="ORF">HYH02_002266</name>
    </gene>
    <organism evidence="11 12">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="11" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="11">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Mitochondrion</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2">Belongs to the zinc-containing alcohol dehydrogenase family. Quinone oxidoreductase subfamily.</text>
    </comment>
    <comment type="caution">
        <text evidence="11">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2452925.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WUW4"/>
    <dbReference type="OrthoDB" id="445556at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005739">
        <property type="term" value="C:mitochondrion"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016491">
        <property type="term" value="F:oxidoreductase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006631">
        <property type="term" value="P:fatty acid metabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.90.180.10">
        <property type="entry name" value="Medium-chain alcohol dehydrogenases, catalytic domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.720">
        <property type="entry name" value="NAD(P)-binding Rossmann-like Domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013149">
        <property type="entry name" value="ADH-like_C"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR013154">
        <property type="entry name" value="ADH-like_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011032">
        <property type="entry name" value="GroES-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051034">
        <property type="entry name" value="Mito_Enoyl-ACP_Reductase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036291">
        <property type="entry name" value="NAD(P)-bd_dom_sf"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43981">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43981:SF2">
        <property type="entry name" value="ENOYL-[ACYL-CARRIER-PROTEIN] REDUCTASE, MITOCHONDRIAL"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF08240">
        <property type="entry name" value="ADH_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00107">
        <property type="entry name" value="ADH_zinc_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF50129">
        <property type="entry name" value="GroES-like"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51735">
        <property type="entry name" value="NAD(P)-binding Rossmann-fold domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="7" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="6" id="KW-0496">Mitochondrion</keyword>
    <keyword evidence="3" id="KW-0521">NADP</keyword>
    <keyword evidence="5" id="KW-0560">Oxidoreductase</keyword>
    <keyword evidence="12" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4" id="KW-0809">Transit peptide</keyword>
    <feature type="domain" description="Alcohol dehydrogenase-like N-terminal" evidence="10">
        <location>
            <begin position="6"/>
            <end position="81"/>
        </location>
    </feature>
    <feature type="domain" description="Alcohol dehydrogenase-like C-terminal" evidence="9">
        <location>
            <begin position="200"/>
            <end position="287"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="146"/>
            <end position="193"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="489"/>
            <end position="516"/>
        </location>
    </feature>
    <feature type="coiled-coil region" evidence="7">
        <location>
            <begin position="384"/>
            <end position="420"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="151"/>
            <end position="163"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="8">
        <location>
            <begin position="173"/>
            <end position="183"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="8">
        <location>
            <begin position="184"/>
            <end position="193"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004173"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00010371"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022857"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022946"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023002"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023128"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="9">
        <source>
            <dbReference type="Pfam" id="PF00107"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="10">
        <source>
            <dbReference type="Pfam" id="PF08240"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="11">
        <source>
            <dbReference type="EMBL" id="KAG2452925.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="12">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="13">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="516" mass="53105" checksum="1DCE9C87BDA16026" modified="2021-09-29" version="1">MKFAPVSAADMYTARLGGVYGTDTAPQLPYTAGHDGVGVVVRVGPGVKELCEGDLVLPLRPFAGTWATATVAHQRALIKLPQDGYGLPLELLAMSRELVVAYTLLEGAGLKPGDAVILNAANSSVGQVLLQLARLLRLRTVAVARPPPQPHAAAPAAATTHTAPPNPRIGADSNSNSNSSTGSSGSGSSGSGGKWEHTVSWLRGLGATEVLKDEGSLRAELDRLHFHARPRLALDAVGGDSAARLADALAEGGELVVYGAMSGRSPALTWQALLFRDLRVRGFNLRRWAAAGVPPPPPAALASAAAGSAAFGGGLSGGSSGGPVRYRAALEALGKLVAAGMLTVAYTEYDLTEFPEALEHALERGRDTKVLLSCGRCGPAAEMLAALQQQVQQTQVHQQQQQQQQQQQQQQQQVQQVQQVQQLGAGVVPLAGASDVEVEEEREKPDVVAAAAAQPIPTGAGSGAGKQVKFALELGDEVEAVAGGVGVRAGLKKGKGGAQRGGKPVVISTADATSVE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUX6</accession>
    <name>A0A835WUX6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">Guanylate cyclase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_002078</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453872.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="568473at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0009190">
        <property type="term" value="P:cyclic nucleotide biosynthetic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="GO" id="GO:0035556">
        <property type="term" value="P:intracellular signal transduction"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.1230">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.190.10">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001054">
        <property type="entry name" value="A/G_cyclase"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR050697">
        <property type="entry name" value="Adenylyl/Guanylyl_Cyclase_3/4"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029787">
        <property type="entry name" value="Nucleotide_cyclase"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081:SF1">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43081">
        <property type="entry name" value="ADENYLATE CYCLASE, TERMINAL-DIFFERENTIATION SPECIFIC-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00211">
        <property type="entry name" value="Guanylate_cyc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF55073">
        <property type="entry name" value="Nucleotide cyclase"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53850">
        <property type="entry name" value="Periplasmic binding protein-like II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50125">
        <property type="entry name" value="GUANYLATE_CYCLASE_2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="607"/>
            <end position="626"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="950"/>
            <end position="974"/>
        </location>
    </feature>
    <feature type="domain" description="Guanylate cyclase" evidence="3">
        <location>
            <begin position="649"/>
            <end position="707"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="99"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="321"/>
            <end position="384"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="764"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1161"/>
            <end position="1198"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1212"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1319"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1372"/>
            <end position="1391"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1575"/>
            <end position="1595"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="99"/>
            <end position="117"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="118"/>
            <end position="128"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="321"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="771"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1168"/>
            <end position="1185"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="1221"/>
            <end position="1231"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1337"/>
            <end position="1356"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1578"/>
            <end position="1591"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="PROSITE" id="PS50125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2453872.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1651" mass="166390" checksum="46A4C8FE0EF74D9F" modified="2021-09-29" version="1">MEGNGTTGSGTNQLQVMVPTRLFPAYSRLARSYSLASPSMAVAVVPVDEDQLLQEALFEFSNKLNTMHDAWILQLDSYWQLEALNAILDLTNLTTAAAAGGSSSSSSSTSANTSGATAGAGSGGGGGGGGWAEVPPAFRRLSYSYDLVNIPPGMPATPTQMSLPLDGSAPLMLYRTDMLAAAGLRRPPATWAEVLAAAAAINGTDMDGDGLAEYALCFRPDTDCSYTSALGMVLLPYLQYNGTASGGFLAPEDLTPLLDSPGAAAGLALFQALLGFHIPLDLQGIECAAGDVALAFAEGECAMAFGWGELFKLSEVGTSVSGSGSPQVSNNNNNNNNNNNSSSSSSSSSSSSSSSSSSSSSSSSVAAGRQRSAKGRYAMAPLPGSSQVYDRQQRALVECGSAVQCPFGLGGRPEPLSTKDGRTLFVNRAPYLPYTGVVGLVAAGVDPARQREAYDFLAYLSAANLELSLSNDNPIVPFRTTALSADRVADFVAAGFDEAAVRSYMAVVNDTAHHPNLAPGPIIPRGEMLRAALAVAAANLSAGMDVARVAAALQAQVVDQVLNYQPTWSWRLGLKAAYWAATGYTPPPVNGTGGGDAGSSEMPAVSLAVPVASAVVVLLLSTLYEFKKHRQHRSLFGKVVAPGPFEDTTLLVTDIQDSTALWEMLSSSVMDRAIKEHHTCLRKLLLKHSGYESATEGDSFLLAFHCPEDALLFAMEAQVALLECAWPMELLDCDVCRPAYVVHNDGDKRANLLADGGDMGGGGGGLMALPRTNSGLSNKSTSEDTSSPQASNLLGTSGATGSVMSAGESNTFLTACQASWKEATAATPNNVLIFRGLRVRMGMHTGISNEADVAYNKAAARMQYSGEILNYGKSVSDAAAGGMILLSEATYRRLPMERLWDKALVMHVGEYRLKDDLPVLPLYQVTGRRLMGRLGHLAGMRFKEQLSRGVFTAPLGAVAMVYVGVAGVTALLGWDEGLTREALALLHACLGEHVRTWGGYLVEAADEQVHVVFPSASDAVLFCLAAHQAAMELPWPDALLDHELAEELIVGDAVVFRGLRLKSGVDVGHAVGEVNALTGRICYRGKVVARAARIMQNASSNQVLTSGEAWAAALSANAAVLQLRGVVGDRLGPFKLRGVAERVEVVQVRLRRLDLPGAEGWAQDLQQGGDGPGGGGATDGEGGTTTDGDGPAQSTRPGSLAAVDLGLAAAAGDGGGGGGSDRPASSSRFGFLGRRSSHASMMPTANGGDAGTRGAAAAAMASPLLQASRLGADGATTGGGGAAGAGSGPASPRLFAGLLRSAARAQSFSVATSGLIARMTRRGRTGSGAPSRTQTGGALGGQGVDGSGGSGSAASGGGITITSGGVGIQAVVDSGGAPADPNRQSIGGGTPSGGFLRSLWLGSNGGGGAGGGVSPGLTFPFTSAKRLLPSWGSNGQSNHNGGGGGSGNVAAAVATSIPANRVGGNSGGYHYMAVDASLGGASVASAAAAAGGTAAVPLPSLTATPAAALMLQTQAPAPASVDGAAGSGTPAAGSAARAVAAAAAAFLAAGGASPISPKAVDATVLAAAGAAAAAAPGSGRGAVSGGAGSSDGPGWFPGEMLADVLQGVQEEDEAAAAAAAAASSAGMSGVVAATGRQLAAAASPTRAAAHM</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="13" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WUX7</accession>
    <name>A0A835WUX7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_002490</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000004">
        <property type="protein sequence ID" value="KAG2453166.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="544551at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005524">
        <property type="term" value="F:ATP binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0004674">
        <property type="term" value="F:protein serine/threonine kinase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.200.20">
        <property type="entry name" value="Phosphorylase Kinase, domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000719">
        <property type="entry name" value="Prot_kinase_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR017441">
        <property type="entry name" value="Protein_kinase_ATP_BS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001245">
        <property type="entry name" value="Ser-Thr/Tyr_kinase_cat_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR008271">
        <property type="entry name" value="Ser/Thr_kinase_AS"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051681">
        <property type="entry name" value="Ser/Thr_Kinases-Pseudokinases"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329:SF214">
        <property type="entry name" value="PROTEIN KINASE DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR44329">
        <property type="entry name" value="SERINE/THREONINE-PROTEIN KINASE TNNI3K-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF07714">
        <property type="entry name" value="PK_Tyr_Ser-Thr"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SMART" id="SM00220">
        <property type="entry name" value="S_TKc"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00107">
        <property type="entry name" value="PROTEIN_KINASE_ATP"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50011">
        <property type="entry name" value="PROTEIN_KINASE_DOM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS00108">
        <property type="entry name" value="PROTEIN_KINASE_ST"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5 6" id="KW-0067">ATP-binding</keyword>
    <keyword evidence="4" id="KW-0418">Kinase</keyword>
    <keyword evidence="3 6" id="KW-0547">Nucleotide-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0723">Serine/threonine-protein kinase</keyword>
    <keyword evidence="2" id="KW-0808">Transferase</keyword>
    <feature type="domain" description="Protein kinase" evidence="8">
        <location>
            <begin position="825"/>
            <end position="1237"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="721"/>
            <end position="798"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="1035"/>
            <end position="1058"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="732"/>
            <end position="742"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="781"/>
            <end position="795"/>
        </location>
    </feature>
    <feature type="binding site" evidence="6">
        <location>
            <position position="852"/>
        </location>
        <ligand>
            <name>ATP</name>
            <dbReference type="ChEBI" id="CHEBI:30616"/>
        </ligand>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022527"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022679"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022741"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022777"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00022840"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU10141"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50011"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2453166.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1347" mass="142627" checksum="11E06C8D866B2B68" modified="2021-09-29" version="1">MSNLAFTPDNWPRPVQIVRAVTLYSPYRVKLDLCGGGQPARVLLNVTSSGSLLVQRFFLRNLMPSTPQDLTGFGPVPAFLSSGGRVSFSVVVFHFLPATTWVFTAPPGQSFWARERSSPGVMTEIYTGGLLQLEVPALYVLKYSSPQYSLAVCYSPVDLESCYADNDEQTTLVYCLYTFADALRNPHVRYARVFHDIGVDRVAYNPRNPIVLTTPKTYSACPGARPSMNMDAVYAGVAVRASLELIGLRFRGSLPTNYTTWPRNLPLLLGLLDNDGAGSISLINSTVEVPDLPRTVRILKSLPSKEVADPSRPNLQPSVDAWPTPSALADAQAIMDSPNVVAGGGWIVGAWAFRTFNIHPSTGLVGSIGITPELPAVPGFHISNWVLSQNAWQQFASLNVYDSFSTPNAAVWRFSNVRVEQANITNVRSVCFGAAVEQGATMRSQVAVVATDAQLRAALVRAARYIQVVADIKFDPANWPTGDNALLVEAGIIEVRGCHPTAGKRYTVDLSNLRGVVRSSGRLLLQGNLRFVNLGWTSLSANEVAALANGGMDMSLLGAFEVVPNRAGGLGTVELEGVLLQEMLGAPGAGALRPSDLLAVLHLTDVTPALRLRNVTVGSSGAMLGMWGMDESGTQSGSWVFINTEVQWAPSESSTAAAGTDSGSDNSSSTNVVAIAVPVAVGGAALIAAAVVAFVYLRRRNNGSGSSVKAAAYACKDVADPEVGAGGRKTMDNSSSTSTTGDMATGLAVAKQSTGNGDAPDSMGSGHGTDASTAGGANFTPRASTTPEGPTSSRGPLNDIDAAKRAIAAGRPSLAPCSRTAVDELELQAILGEGSYGRVYRALWRGTTVAVKVILLPARMSGRERHQRMAVMEAAISSSLSHPNVVQTYTYTVEEVQGAKARAASRLQNESLNHSTNPNSVPGMQALSVGTQDDISGTAGGAPSNTCDLVGYEIRLVQEFCDQGSLRDKLNERVFFKPMPAALAGASASLTDTERPVSMPANSPIAGAGADAATPGRVGGARNILAAVMEQNGGRVPTRRSSISMTTERMDSVDGSGSAAPAKPVMMVDLAAVLDTAIDIARAVAHLHREGIVHADLKSRNVLLKGSTHDPRGFVAKVADFGLSMRLDHDETHVSNAFHGTLVYMAPETLLKGHVSRASDVYSFGILLYELYSGETAYKDVPKALLGHAITKDNLRPVFPPALGAPFEYQLLACRCWESNPEIRPEFEFIVDELKRMRGRLCGSGEGVSAYGNSNAGSARRTDAGTTLDGARGLAPDASVGSSNLVAGGFLRPSIKPRPAEQWGMPSIHDDELEHEDEQFVATTGAGLHSGSLDHTCRSEAELKELH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A835WYA7</accession>
    <name>A0A835WYA7_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="8">C3H1-type domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_000634</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454801.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A835WYA7"/>
    <dbReference type="OrthoDB" id="749011at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008270">
        <property type="term" value="F:zinc ion binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0010468">
        <property type="term" value="P:regulation of gene expression"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-ARBA"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.1370.210">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.25.40.20">
        <property type="entry name" value="Ankyrin repeat-containing domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR002110">
        <property type="entry name" value="Ankyrin_rpt"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036770">
        <property type="entry name" value="Ankyrin_rpt-contain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045234">
        <property type="entry name" value="Unkempt-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR057444">
        <property type="entry name" value="Znf-CCCH_AtC3H23-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000571">
        <property type="entry name" value="Znf_CCCH"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493:SF50">
        <property type="entry name" value="RING FINGER PROTEIN UNKEMPT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR14493">
        <property type="entry name" value="UNKEMPT FAMILY MEMBER"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF25512">
        <property type="entry name" value="zf-CCCH_AtC3H23"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00356">
        <property type="entry name" value="ZnF_C3H1"/>
        <property type="match status" value="2"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF48403">
        <property type="entry name" value="Ankyrin repeat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50088">
        <property type="entry name" value="ANK_REPEAT"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50103">
        <property type="entry name" value="ZF_C3H1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="5" id="KW-0040">ANK repeat</keyword>
    <keyword evidence="4" id="KW-0238">DNA-binding</keyword>
    <keyword evidence="1 6" id="KW-0479">Metal-binding</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="3 6" id="KW-0862">Zinc</keyword>
    <keyword evidence="2 6" id="KW-0863">Zinc-finger</keyword>
    <feature type="repeat" description="ANK" evidence="5">
        <location>
            <begin position="100"/>
            <end position="132"/>
        </location>
    </feature>
    <feature type="domain" description="C3H1-type" evidence="8">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="zinc finger region" description="C3H1-type" evidence="6">
        <location>
            <begin position="255"/>
            <end position="282"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="157"/>
            <end position="205"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="334"/>
            <end position="357"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="422"/>
            <end position="500"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="518"/>
            <end position="559"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="7">
        <location>
            <begin position="761"/>
            <end position="792"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="162"/>
            <end position="178"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="336"/>
            <end position="349"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="7">
        <location>
            <begin position="422"/>
            <end position="441"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="455"/>
            <end position="466"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="474"/>
            <end position="495"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="530"/>
            <end position="539"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="7">
        <location>
            <begin position="761"/>
            <end position="783"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022771"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022833"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00023125"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00023"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00723"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="8">
        <source>
            <dbReference type="PROSITE" id="PS50103"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2454801.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="869" mass="87741" checksum="33E1CC06611951FA" modified="2021-09-29" version="1">MARPNEDSEVIGHYLVPANGRPAQPLLHESSTLFVDVVSDKLSAVESAVEADTSKLQTLYLILHWASSPDGQGVAGSSPEACSGSLDAAAAAGRASVTVKQRTLLMVAAHSGSLRVLAYLLARGAEPSRKSPDGMTAYDMALAGETPQAPTAIAMMRDADSHPSSSTRSSGSTTDTHSYNGTEGARMGNGRQDESEGSSIFNTSDLTRPEYSTDDFRMFNFKVLRCSKRHAHDWRACPFAHPTENARRRDPREFKYCALACPDYKQGFCIRGDVCPYSHGVFECWLHPSRYRTQLCKDGSNCHRPVCFFAHSLPELRAPTYTWVPSPADLAARPYSATSPTNSGPNGVNSAGGGATGGGGGTLPPAAAAMAAMALGAVSPNAAASMQQQLQKQQSGQCLESSSVAAEARALLSHRLSGIPVATSSSSDGAMSGPGNTSPRGQQVMMLMSGGGVNGSSASSSALVLGTHGGGTTTTGSSSSSSGANGAQSPSSGGSMAEGCNGTSGALAAAAAAVAERSDKDGGKGGHSGANGNNNANGNTNGGANGNANANGGKPINLTQPNAAASMLGFTAPRMSNAFARRHGLNPKDNPMINLQKIALQTQQQQQAQVQAAAVAAAAAAQQQQQAAVQQQAVQAQVAAQMQAGLPVGVGGAGILAAGVGGRAATTAGQRLNAAAAAAAAAAAAAAATGHAGLGSIPFGAQSAAGAAAYGMNSLYAPMQVSQMQAAAVAGLNAAAPGADASLLAAQLAALNLQQQQQPHARQMLAQQQQQQHVHVQAQMHTQSGPAGLSQPGAQLGGLGMGAIGGMNMAAAAAAAAAAGMGHGSVQYLSSGAPHPSLMHHQGMVYSGSLHAVHMFDQQQYQLGAQTEV</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B0R3</accession>
    <name>A0A836B0R3_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_009053</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000029">
        <property type="protein sequence ID" value="KAG2444112.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="OrthoDB" id="546096at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="88"/>
            <end position="180"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="235"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="344"/>
            <end position="499"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="720"/>
            <end position="773"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="786"/>
            <end position="981"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1017"/>
            <end position="1099"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1199"/>
            <end position="1222"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="88"/>
            <end position="102"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="138"/>
            <end position="154"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="252"/>
            <end position="271"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="289"/>
            <end position="298"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="349"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="383"/>
            <end position="398"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="453"/>
            <end position="484"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="810"/>
            <end position="834"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="852"/>
            <end position="880"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="881"/>
            <end position="896"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="897"/>
            <end position="907"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="915"/>
            <end position="924"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="925"/>
            <end position="938"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="946"/>
            <end position="967"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="1058"/>
            <end position="1086"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2444112.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1311" mass="139618" checksum="36B946006FFB8490" modified="2021-09-29" version="1">MGKSSAKSQARRPVNYWSKFNDWWRTVLDETGRRPEAAAINKWYEENAADTWAPHEMPTVLETRVHAKCLRSVDEVRNYFRAYRAQRRADAMHGRDNGRDCGDEGDPDVPAPRGGSRRPGTAPSKTGTHKSGVTKVVASSGRSSRSLGGRAGSSQYGTEDYATGADSAWPPPQQRQHSLDQTHMTHMAGSYEQHGGHMSLQHPPLQLPSQQHRVRIHIRQASAGSGSANVSSGAITGACQPAGPMGLPRHPPLQHHQHQQHYQHQHLHQHQMRNSAQLAHSPPDQGGVDGKEGRPDVQRGDMAYATTEAPCSSVSTASLDDLLRLHDENDMALQDDAAYCAAMGLPPHQQQPPPPHHQQQQPPPPQQQQQQLGSAPNALGSGAATGNGRGGRSGGSGSEGINLKQVMQQRHSAPTLPGLTDNVPRPGMHGNPQLHHQAYPSLHSAQPHYGNPQQHQYQQIQQQQQLQLQPGKQGQAQQMPQSQQRSSGNIGDLGSMWDELDGASEPTIYAQLTLLPRSNVKLEPQPEACTQQEQQGAGAFEARQHQQQHHMLHQQNQHMQQQQQQQHQMLQMQNGSKPARVLWSPLLSVRPMPVAPQPMPQQQQQYAQNSGVVQHAGGMQGGQQCHAPQQMQQALQQPPALPPFPSGWGLPPLEQQAQAPRISVNGSAVVPMDGVSCQQDAVGWTRDAAPPLPASMLMGTGGGSFGNGLSALQIRHEPHELNKQPNGGPAGQSGCSSVAGLSEPQPMAGSAPTENLEQPMSQPSQPAPGPAAVHSLWASEQGGDTEMVASGVAPPQAPHNTPTWYTPHMQQQQQQPGQPHDAALQQRLLQLQSAGGSGSAGPSPLPTPTGPPSASAPSAGQLAQSPSMPAVQQPQQHLPLAPVPPLPPLPPFPPRHQPQQPQQSAGPTPQPSQPPVQHQRSSSSNSGMMTPGWANQQPGHLGRPLSTSSSCSSWQSVPSAPASVQQPLPVPPSVPGSAASGPFSTMMGVRVTSWSSTPENSQGSGPATLSRPFEVSAMSQQLHAPSQPPPQPQPQHQEAQKQSLQPAAVAMPGCPNTAFANQQHQQNPVASVQQQHVPAAPVTSSPVRVRRFSQPGPDEQSRLALLQQHRHFMQEQLQAQHLQQQQQQQLQAQHLQQQQLPVQQAPQQTQTHMLPPSNSLPCVLPDIRTSMADAKVNSQAHGNGTGDGQTPALGRHVVTTGNATRPPLMRTLSAPPSETPSANVGAGGPFGDAAPVPQGHGTSGSGMALPGVTPRNQMLQAGGAGGGFGTPGMGMTSPAGWGDSALAELEGDSAWLRNMLAPDSLTSSLWG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3V1</accession>
    <name>A0A836B3V1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="1">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="1" type="ORF">HYH02_008000</name>
    </gene>
    <organism evidence="1 2">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="1" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="1">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="1">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000024">
        <property type="protein sequence ID" value="KAG2446842.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3V1"/>
    <dbReference type="OrthoDB" id="537362at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-1185">Reference proteome</keyword>
    <evidence type="ECO:0000313" key="1">
        <source>
            <dbReference type="EMBL" id="KAG2446842.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="349" mass="38913" checksum="F840995FC7C0B19A" modified="2021-09-29" version="1">MELLDALLRKHGGDTSGAPRTAYQQGEPVRELVRAAMRETWLEFAAQQQRARKPKSFSKASSTDVDALLHCAQLQHVRGEALAPQDVQIPAGTPECDSFVWEQGGGENAMTPELLKYHQTQLEKFGVEFDKLGGFEMHDTHSKGKLIPFNCGGRYFSGGFDGCVAPYGLNQESVVFQSRIIYEHKCREMTTTDKQQAIVELLGAYAYNSCPVLLDLTNGRTHNIYTIRGTCVYVWKDLKPTQAYILQARHLQAADRLRAALDLQLGQIPEEEQRTMRHVQQALAPVIGGAAALQEQLDSLLPFMAPEERELVSQDLVRSWAQGADFTQPPEEQIQIPALSLPATPSFYI</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="12" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B3V6</accession>
    <name>A0A836B3V6_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="6">RRM domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="7" type="ORF">HYH02_008503</name>
    </gene>
    <organism evidence="7 8">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="7" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="7">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="7">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000026">
        <property type="protein sequence ID" value="KAG2446514.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B3V6"/>
    <dbReference type="OrthoDB" id="431068at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003723">
        <property type="term" value="F:RNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="GO" id="GO:0006397">
        <property type="term" value="P:mRNA processing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008380">
        <property type="term" value="P:RNA splicing"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.30.70.330">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR012677">
        <property type="entry name" value="Nucleotide-bd_a/b_plait_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR035979">
        <property type="entry name" value="RBD_domain_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000504">
        <property type="entry name" value="RRM_dom"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23139">
        <property type="entry name" value="RNA-BINDING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM00360">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF54928">
        <property type="entry name" value="RNA-binding domain, RBD"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50102">
        <property type="entry name" value="RRM"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="3" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="8" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2 4" id="KW-0694">RNA-binding</keyword>
    <feature type="domain" description="RRM" evidence="6">
        <location>
            <begin position="124"/>
            <end position="208"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="5">
        <location>
            <begin position="1"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="5">
        <location>
            <begin position="9"/>
            <end position="21"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="5">
        <location>
            <begin position="22"/>
            <end position="40"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022884"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="PROSITE-ProRule" id="PRU00176"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="6">
        <source>
            <dbReference type="PROSITE" id="PS50102"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="7">
        <source>
            <dbReference type="EMBL" id="KAG2446514.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="8">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="300" mass="32249" checksum="9F06687880101919" modified="2021-09-29" version="1">MGSRDRSRSRDRRRSRSRERSRRWDRSRSRDRDRDRDRDRRRSRSKSRSRSRDRNKSSGALDASISAVQAMAALQQQQQLQRQLLAQQMLLQQQAAAAAAAAALSKPAMAQQSTTAATADRKSREIYVGNLAIGVVTADMLKELFNTILANQVADPVSTPPVVNVNLDPSAGRFAFIEFRTRELTDAAIQLDKLELCGRQMNIGRPKGYVDPNAHLVNAAKLGQAQVALATAQFALPGAAVPGALPGAAAALPGALPGLAGAAGLAGLMVTTPTAVVLLENMVTCATIRDDTERKEVSAG</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B498</accession>
    <name>A0A836B498_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">Protein kinase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_007916</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000023">
        <property type="protein sequence ID" value="KAG2447172.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B498"/>
    <dbReference type="OrthoDB" id="2436248at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.510.10">
        <property type="entry name" value="Transferase(Phosphotransferase) domain 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR011009">
        <property type="entry name" value="Kinase-like_dom_sf"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56112">
        <property type="entry name" value="Protein kinase-like (PK-like)"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="506"/>
            <end position="531"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2447172.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <evidence type="ECO:0008006" key="4">
        <source>
            <dbReference type="Google" id="ProtNLM"/>
        </source>
    </evidence>
    <sequence length="629" mass="64506" checksum="083955AC76B0189F" modified="2021-09-29" version="1">MEQADTNFISGLADEFGLGPAWELSAVTAFTGASAEIRAYIRGRPHNNKQVDLLNELMQASAAGLGVGNAAGAGGAGSAVGPLGVEVAAGAGGPDTSTEYIRRVLLKPLGAANVGGGGGDGGLLMMSAPAAAAVARLSDQPLGAKLPVLGRMAQSALASNSELGDYVVTAEADARLAADAYTLCMITTSALMGMSCNQFGGSETFTTVQMARLVDDPLSLAATSLGLHVRTDRNTTDRSGATGRQLRPDFLCWVDNVLLFKGEEKANASDLETAITELEARMATSWNPALLPGVSMPCMFAYAAAGSAVQFFAITSSGGGGAVQATAISDLLDTGTPLGRIKVVHHTLVIVRALAAYAPYAPKITMALGGRVGLGGAVEVFSEFVRKSVDLAQQHGTVMGYPGLADMYRTLSGVCCPNLVRLHSGSSSGAGGGGGSSSIRLQADGRTLVLHLEPVGLPLHGAPASEADLKQALRHVLTAVAALHAAGFVHRDIRWHNVIRLPAAASASTAGSQQPPPSAASSSSGNSSSPAGADTYVLIDLEHAAPADCDLDCRQPPHRLHTWPAADGLLDPATGRYTRQSDLCLVAAALMANLPFALSDAGRDLRQQLATRQVPSAEAALHHAWLCAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="9" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B7A5</accession>
    <name>A0A836B7A5_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Ndc10 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_005091</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000013">
        <property type="protein sequence ID" value="KAG2449558.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B7A5"/>
    <dbReference type="OrthoDB" id="549491at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003677">
        <property type="term" value="F:DNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="CDD" id="cd00084">
        <property type="entry name" value="HMG-box_SF"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.10.443.20">
        <property type="entry name" value="Centromere DNA-binding protein complex CBF3 subunit, domain 2"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR036910">
        <property type="entry name" value="HMG_box_dom_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR038279">
        <property type="entry name" value="Ndc10_dom2_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR031872">
        <property type="entry name" value="NDC10_II"/>
    </dbReference>
    <dbReference type="Pfam" id="PF16787">
        <property type="entry name" value="NDC10_II"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF47095">
        <property type="entry name" value="HMG-box"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="Ndc10" evidence="2">
        <location>
            <begin position="137"/>
            <end position="372"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="584"/>
            <end position="713"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="757"/>
            <end position="786"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1026"/>
            <end position="1101"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="674"/>
            <end position="683"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1047"/>
            <end position="1065"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="1073"/>
            <end position="1082"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF16787"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2449558.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="1158" mass="121366" checksum="59B1EC2A9A556F8D" modified="2021-09-29" version="1">MIRELSYLNATRRGIIEKAGENAGDYKPFRTAVKSAKKDAKGARLRKADVHAGTCNDTYTLAEYREMARLLAGGQVTMGKLRWRDLLKVSMTQLFVHLMHFGAGRGDDTRVMRLSYIGRPREVEVLSGGGARAFMLPITLYGAKHQKSDKPNYIALMRTKDVLCCAIRSLAESVFVRFVLYPEPFPDVGEADWDLRPLLRGLGTDVNEGLTYENMADWTKAVFAYLNIIIRKVTHAMRIGGSQALAMQGVPLNVIQRWGRWFEGLSILMAYLTNAPADGLLAMAGFGYHTGEQMKGKYWAPRFMATMPQPMLEELSVYLFPFLPQLRKQSAALPTTGKDRSISASSAVEVMTFLAQVAVQDSLEMADIVPSNPVVVRFANHPTWLHARNAYKDCLAKGVFSAARPVTMLDVMQQQQAQLMLYSARLEALPQLVVAQLAQVLGGGGGGASAALQCAAPLGQTSSSSLSAGAPFAQLQQLVGLGSHMAPQGIALGAYAQLQQHLGSGGSASGGWDHTGLQGTTPAPYVHQLSQQQLSGGGNSGCFPGFMGLQGAAQWTYAHQLQQQQQQLSGGSLPGFAGLHGGGISLPGVTGPQGAAPGPYAHQPPPQQLSGGGGGGCFPGFMGSQGAAPGPYTHQPPPQQLSGGGGGGCFPGFMGSQGAAPGPYTHQPPQQQLSGGGGGGFLGFMGSQGAAPGPYAHQPPLQQLSGGGSGGCAGSGGGSDCSVIGLHGMRLQDIAPPPLSPPALSPSSLLQPSASALLRPPHVPQPGGAPATVPHHPVRPPDTLLSPLSRSRAAFQAASAAMVAACEGRVGVLQEATAMPGAAVPGHAGAAPAKGAAGGKKRTTAAAAVEAAAAAVGKVKDAAQSGTAPAGGGSAEASGAKKELWVWRKDIAGLCVADGASPWLRPPATLCDLWSLWVKGWPGVAPPFADLFEHYGDSWYPSGDFRKRMHELKQLYHWCITKTVEVRGGSREAAAAFWTAKQEHYGRFTASGRTPELKPYWEKFVKPLSTKPDNFVAYVREQRPQDYVSPTKSMAEAERQASAGTRGVRGGVHGGVSGSGSGGGSSSEAGGAALAGGGGGGSSNAPSGGQPAVQLEKPSVTGQHLWMRKREGRVEGMPLKELNTLWAKLPAEERAYWIRRCADEKAAYKIAMASKQQE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="11" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B8B3</accession>
    <name>A0A836B8B3_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="7">Pre-mRNA-splicing factor 38</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="9" type="ORF">HYH02_000306</name>
    </gene>
    <organism evidence="9 10">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="9" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="9">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="function">
        <text evidence="7">Required for pre-mRNA splicing.</text>
    </comment>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1 7">Nucleus</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="2 7">Belongs to the PRP38 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="9">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000012">
        <property type="protein sequence ID" value="KAG2450204.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B8B3"/>
    <dbReference type="OrthoDB" id="3881at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005681">
        <property type="term" value="C:spliceosomal complex"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-KW"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-UniRule"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR005037">
        <property type="entry name" value="PRP38"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR23142">
        <property type="entry name" value="PRE-MRNA-SPLICING FACTOR 38A-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF03371">
        <property type="entry name" value="PRP38"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="3 7" id="KW-0507">mRNA processing</keyword>
    <keyword evidence="5 7" id="KW-0508">mRNA splicing</keyword>
    <keyword evidence="6 7" id="KW-0539">Nucleus</keyword>
    <keyword evidence="10" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="4 7" id="KW-0747">Spliceosome</keyword>
    <feature type="region of interest" description="Disordered" evidence="8">
        <location>
            <begin position="170"/>
            <end position="383"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="187"/>
            <end position="197"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="220"/>
            <end position="229"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="252"/>
            <end position="337"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="347"/>
            <end position="364"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="8">
        <location>
            <begin position="372"/>
            <end position="383"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004123"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00006164"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00022664"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="4">
        <source>
            <dbReference type="ARBA" id="ARBA00022728"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="5">
        <source>
            <dbReference type="ARBA" id="ARBA00023187"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="6">
        <source>
            <dbReference type="ARBA" id="ARBA00023242"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="7">
        <source>
            <dbReference type="RuleBase" id="RU367025"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="8">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="9">
        <source>
            <dbReference type="EMBL" id="KAG2450204.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="10">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="383" mass="43194" checksum="C9D1B20E35A9153D" modified="2021-09-29" version="1">MEIHGSTTTFNLENVLRQNILNSDYYKGTCSELSNWSDIVDEIYESVDHVEPWMSGNARGPSTAFCLLHRLFTLKLSAKEVKDMLDHKDSPYIRAVGFLYLRYVGDPKTLWGWVAPYVKDQEKFSPSGPNEKEVAMGDYVRDLLLSQYYFETIFPRIPKPVQDQINDELTKRSLPTTAKGNGGAGGTDRRGVDDSGNRRPASVKASLSVAFGQRAPNRSGAREEGRGRDPSLAQRDGAAAARGGRGSASPEPPRDRREAPAPRRDYDRDRDVRGGGAGADRRDNRDYGRDKDRDRGRDYDKSREYGKGRDYDRGRGDRDRGRDYDRGRDYDRGRDYARGGGAGGGRGYDDRRDERRRSRSRSQDRNGGGASRDARDVFKDARR</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B8B5</accession>
    <name>A0A836B8B5_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_004578</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000010">
        <property type="protein sequence ID" value="KAG2450741.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B8B5"/>
    <dbReference type="OrthoDB" id="546256at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="247"/>
            <end position="335"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2450741.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="335" mass="34087" checksum="6133829F2EFFBD2D" modified="2021-09-29" version="1">MVLLLVTHTIEVPSSRVPLSAIILVDAIKRKQLPANLKCRLVIPSAGHHSCSVWDASSVEELQAWIDTNLLDGTASIAEIPEEFTYGLSLELTTARAADKVATTSKTTLERINTTGARVMESMSEKLDARTNLITATRETASAAAAKVKQATSSAMESERVQRGLASLSTSLQSAGTSMNRAFTWVGSKVKESFGAEAGAGFGGAGGAQSYSGFSSEPPSYEAAAYASAPAAAAGLAGAGAGFMPVSTHAARPSSDQHHTYPPQSQHVAGPGPVTEDAGPAPQFTLDEGVASPMLSPTKEAADTDTGGGGKDDDGEGAGGLDTAPMVAPVGAAAT</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836B9A4</accession>
    <name>A0A836B9A4_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="4">AB hydrolase-1 domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="5" type="ORF">HYH02_004178</name>
    </gene>
    <organism evidence="5 6">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="5" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="5">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="subcellular location">
        <subcellularLocation>
            <location evidence="1">Cytoplasm</location>
        </subcellularLocation>
    </comment>
    <comment type="similarity">
        <text evidence="3">Belongs to the AB hydrolase superfamily. ABHD14 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="5">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000008">
        <property type="protein sequence ID" value="KAG2451582.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836B9A4"/>
    <dbReference type="OrthoDB" id="284184at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005737">
        <property type="term" value="C:cytoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="UniProtKB-SubCell"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.40.50.1820">
        <property type="entry name" value="alpha/beta hydrolase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR000073">
        <property type="entry name" value="AB_hydrolase_1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029058">
        <property type="entry name" value="AB_hydrolase_fold"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46197:SF3">
        <property type="entry name" value="AB HYDROLASE-1 DOMAIN-CONTAINING PROTEIN"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR46197">
        <property type="entry name" value="PROTEIN ABHD14B-LIKE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF12697">
        <property type="entry name" value="Abhydrolase_6"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF53474">
        <property type="entry name" value="alpha/beta-Hydrolases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0963">Cytoplasm</keyword>
    <keyword evidence="6" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="AB hydrolase-1" evidence="4">
        <location>
            <begin position="7"/>
            <end position="127"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00004496"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00022490"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="3">
        <source>
            <dbReference type="ARBA" id="ARBA00037942"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="4">
        <source>
            <dbReference type="Pfam" id="PF12697"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="EMBL" id="KAG2451582.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="6">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="157" mass="17256" checksum="1DA789258D950004" modified="2021-09-29" version="1">MRNPTAIFLHGAKYNSDFWLKLGTLKMVAEAGVRAMAIDLPGYGDTPALPYSDNNMRSELVRTVVEAAWARVNATVVLVSPSMSGRYSIPFLDRHGVMLTSYVAVAPIGVRDWGGPWEDTHKRVCALAVYGSKDALVPDAERLTKLFQNSWKAAEEA</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="15" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BA53</accession>
    <name>A0A836BA53_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">Calcineurin-like phosphoesterase domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_003570</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000007">
        <property type="protein sequence ID" value="KAG2451794.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BA53"/>
    <dbReference type="OrthoDB" id="9675250at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0016787">
        <property type="term" value="F:hydrolase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="InterPro"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.60.21.10">
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR004843">
        <property type="entry name" value="Calcineurin-like_PHP"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029052">
        <property type="entry name" value="Metallo-depent_PP-like"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051918">
        <property type="entry name" value="STPP_CPPED1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43143">
        <property type="entry name" value="METALLOPHOSPHOESTERASE, CALCINEURIN SUPERFAMILY"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR43143:SF1">
        <property type="entry name" value="SERINE_THREONINE-PROTEIN PHOSPHATASE CPPED1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF00149">
        <property type="entry name" value="Metallophos"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF56300">
        <property type="entry name" value="Metallo-dependent phosphatases"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="1" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="1" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="1">
        <location>
            <begin position="21"/>
            <end position="44"/>
        </location>
    </feature>
    <feature type="domain" description="Calcineurin-like phosphoesterase" evidence="2">
        <location>
            <begin position="57"/>
            <end position="300"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="Pfam" id="PF00149"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2451794.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="333" mass="36110" checksum="50C9ABE888DC6FEF" modified="2021-09-29" version="1">MAEKSFRRLREALGLIQHGSFFNIRTAVVFLASAALLCGIYLVASAARGTSEREGDIRVALLADAHLIGPQYVCCTESNDVDNESIMKTVERLKAAQQQIEALSPPPAAVVFLGDVIHNGYYSHNFEWYLANRNAYTVGGEIFGNFSVPVRYLWGNHDYHTSCGSAADSYDRTGLSHRLFRHFLGPAALPYSAVQMGRYKLIFLNAMLGPSWDPTHPRCDTKYASLGAEQLVWLERQLGGGGGGGGSGSGGQQPTFVFMHHPLPAALRNEAPELKHPDVLSVLLAHADNIMAVFSGHYHRHSFATIPAAKTAAQGAAAAAAHARDVYFSPMAK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="10" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BBX2</accession>
    <name>A0A836BBX2_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="2">YTH domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_001896</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000003">
        <property type="protein sequence ID" value="KAG2453683.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BBX2"/>
    <dbReference type="OrthoDB" id="306690at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0005654">
        <property type="term" value="C:nucleoplasm"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0003729">
        <property type="term" value="F:mRNA binding"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:1990247">
        <property type="term" value="F:N6-methyladenosine-containing RNA reader activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0000398">
        <property type="term" value="P:mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0048024">
        <property type="term" value="P:regulation of mRNA splicing, via spliceosome"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="CDD" id="cd21134">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.10.590.10">
        <property type="entry name" value="ph1033 like domains"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR007275">
        <property type="entry name" value="YTH_domain"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR045168">
        <property type="entry name" value="YTH_prot"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357:SF3">
        <property type="entry name" value="YTH DOMAIN-CONTAINING PROTEIN 1"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR12357">
        <property type="entry name" value="YTH YT521-B HOMOLOGY DOMAIN-CONTAINING"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF04146">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PROSITE" id="PS50882">
        <property type="entry name" value="YTH"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="YTH" evidence="2">
        <location>
            <begin position="110"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="100"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="266"/>
            <end position="307"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="469"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="547"/>
            <end position="676"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="1"/>
            <end position="22"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="32"/>
            <end position="45"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="273"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="477"/>
            <end position="497"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="498"/>
            <end position="510"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="511"/>
            <end position="530"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic residues" evidence="1">
        <location>
            <begin position="553"/>
            <end position="563"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="606"/>
            <end position="616"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Basic and acidic residues" evidence="1">
        <location>
            <begin position="622"/>
            <end position="633"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Gly residues" evidence="1">
        <location>
            <begin position="642"/>
            <end position="662"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="2">
        <source>
            <dbReference type="PROSITE" id="PS50882"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2453683.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="676" mass="68167" checksum="DC4B9FB3712A0075" modified="2021-09-29" version="1">MADEEDLLYEEDYPDFVDEADVEAGLAAQPTEDAGAPPAGAEEQNGGPGPGEDGGRGDAAAGGSGADKGEEAAARAGGNAGPSGRVATNGGPHGFNARGRPGAAAGGEAIRYFIIRSNSLQNIFISVRTGAWATTRTNDPKLDAAFRSSAEVRLIFSVMGTSAFQGYATMRTAVGAFPKPVVWENGQQFGRPFGVEWRVLFELPHDDCNHIRNRLNDNKVVYVARDCTELPQEQGDQLTRLMAERAAAAGAKPPRQQLAMLEASGRVTPPAMGPGGGGPGRMAGPRGGPMGIPMGMGGPRPRGPGMGPPGIRPGMGPGMDPMAAIMGGPVGPMGPGALLGPGGPGMAGPPGFNMDALATAMALNTFNPAALGAMLQQAGGMMGGPLGGVAAGPSPAMQAIASAMVAHMSNLPPEQQAMAMATIGSSNPLLAEAVAAVIASGGPVGGMGMAGPGGMLGGGGGGAVMVGGGPGPRQGLMMDGGPMGGIQQQQQQQQQQQRGGGGMGMGGSMGMMGQQQQQQQQQRQSLQEQQAMQQLMNMNRDDVVLEGSDGRLRSGRARSRSRSRSPVAGRRGGGGGGPPDFSSMTYDQYLQQYGRVMQEVQQRVGPRGGGGGGGAGWSQRGRSTDRSPQHVREPTPSSQGVGARGGVGDGSMPGGGGAGGAGMASKPGGQPYTEEE</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-02-05" version="7" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCU9</accession>
    <name>A0A836BCU9_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_001156</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454119.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BCU9"/>
    <dbReference type="OrthoDB" id="533800at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="48"/>
            <end position="93"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2454119.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="224" mass="26201" checksum="4BF17CCFED0D1963" modified="2021-09-29" version="1">MSTAPSSEDTRRSNASGLQCDVLRTLVKNNADDDAISTYLGALSSLQTASYREQIDRYRDEIARTREERLQEIDRYRDEIARYREQKLQLQLQLQQEIGHYREEILRLQGDLKTTNAQYSGEVKFLTERLQTTMAQYLRLQGLLSMRGIMEYIQNTMFERTDVKWDRFQAMSCWQDYVNQRPSLQKCLMKRGLVVDTAGGDLVAVYKTLSNNIHDSMTPDEYQK</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-10-08" version="14" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCX0</accession>
    <name>A0A836BCX0_9CHLO</name>
    <protein>
        <recommendedName>
            <fullName evidence="3">D-serine dehydratase-like domain-containing protein</fullName>
        </recommendedName>
    </protein>
    <gene>
        <name evidence="4" type="ORF">HYH02_000727</name>
    </gene>
    <organism evidence="4 5">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="4" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="4">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="similarity">
        <text evidence="1">Belongs to the DSD1 family.</text>
    </comment>
    <comment type="caution">
        <text evidence="4">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454897.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BCX0"/>
    <dbReference type="OrthoDB" id="20198at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="GO" id="GO:0008721">
        <property type="term" value="F:D-serine ammonia-lyase activity"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="GO" id="GO:0036088">
        <property type="term" value="P:D-serine catabolic process"/>
        <property type="evidence" value="ECO:0007669"/>
        <property type="project" value="TreeGrafter"/>
    </dbReference>
    <dbReference type="Gene3D" id="3.20.20.10">
        <property type="entry name" value="Alanine racemase"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Gene3D" id="2.40.37.20">
        <property type="entry name" value="D-serine dehydratase-like domain"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR001608">
        <property type="entry name" value="Ala_racemase_N"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR051466">
        <property type="entry name" value="D-amino_acid_metab_enzyme"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR026956">
        <property type="entry name" value="D-ser_dehydrat-like_dom"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR042208">
        <property type="entry name" value="D-ser_dehydrat-like_sf"/>
    </dbReference>
    <dbReference type="InterPro" id="IPR029066">
        <property type="entry name" value="PLP-binding_barrel"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004:SF2">
        <property type="entry name" value="D-SERINE DEHYDRATASE"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="PANTHER" id="PTHR28004">
        <property type="entry name" value="ZGC:162816-RELATED"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF01168">
        <property type="entry name" value="Ala_racemase_N"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="Pfam" id="PF14031">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SMART" id="SM01119">
        <property type="entry name" value="D-ser_dehydrat"/>
        <property type="match status" value="1"/>
    </dbReference>
    <dbReference type="SUPFAM" id="SSF51419">
        <property type="entry name" value="PLP-binding barrel"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="inferred from homology"/>
    <keyword evidence="2" id="KW-0456">Lyase</keyword>
    <keyword evidence="5" id="KW-1185">Reference proteome</keyword>
    <feature type="domain" description="D-serine dehydratase-like" evidence="3">
        <location>
            <begin position="186"/>
            <end position="286"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="ARBA" id="ARBA00005323"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="ARBA" id="ARBA00023239"/>
        </source>
    </evidence>
    <evidence type="ECO:0000259" key="3">
        <source>
            <dbReference type="SMART" id="SM01119"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="EMBL" id="KAG2454897.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="5">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="321" mass="33915" checksum="705FDD5E09A50957" modified="2021-09-29" version="1">MHVATSREALAVIAPRKIDRLVGLAAAGARVGVCYERADNLRRLNAAAAARGTHLDVLVELNVGQDRCGANSPQEVVELARAAAGLDNVRFAGIQAYHGGLQHVRDPRDRAQRVGQVVARARAAVDALRAAGLPCDTVTGGGTGTYRIEAASGVFTEVQPGSFAFNDADYARNVQEDGSVGEWEQSLWVLTQVMSVTPARGLAVVDAGTKAVSLDSGPPRLPPAFEAVHGVLMEYGSGGDEHGKLMWPQGAYQLPMSLPELGDLLLLQPGHCDPTVNLYDWVVAVRRQQQGQGGGSRTAAGGLEGWRVEGVWPIRGRGPGH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2025-04-02" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCY1</accession>
    <name>A0A836BCY1_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_000755</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000001">
        <property type="protein sequence ID" value="KAG2454927.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BCY1"/>
    <dbReference type="OrthoDB" id="541698at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="1"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="53"/>
            <end position="121"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="150"/>
            <end position="259"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="279"/>
            <end position="312"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="334"/>
            <end position="400"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="417"/>
            <end position="465"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="23"/>
            <end position="33"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="80"/>
            <end position="98"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Acidic residues" evidence="1">
        <location>
            <begin position="175"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="185"/>
            <end position="221"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="228"/>
            <end position="242"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Polar residues" evidence="1">
        <location>
            <begin position="292"/>
            <end position="302"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2454927.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="639" mass="65128" checksum="F779157F2387CB46" modified="2021-09-29" version="1">MHAAPQVLSKALNTHNFRKEQQETTSGAKNPTSILGRAAESLYNARHGLARLFGAESTDDPGAVPKPPPDLLGEPGRTKPSVSSDDPSGSPGPAQPGRGRQRRGSVTTYTLNLPGAGGSVEREVRRLAGYDGVAMGPGLVSRRSLEMLQGPSRSCNDVQAFDGAANGEAAKESSDNEEGDDEDYSFQGGKKQQQQQQQQQQQQLHQPWAAGSGVSAGAPSVQRRASSHDTIAAAAAAEASSSGMEVTDLSPSESGALPDAHLTRLGGGLGGLSVARSALQSGGGPLTHRSHAGSSSQLTVNVPSGPGGATAQLGLLRDRKGGAAAAVSTSGLRRITGDGYASSPGALSPMTPFGSAGAFGHTGTYSGPATPVPGASPGASAIPRLPNLQPAAPSRAGSKSQIVTGPVYSVGALAASISPGGGSDSRPGTSSRARRVSVATSDPNLTDTHGSPGHSGTSGGGRWYQQDTGDVEAVLAGAEEAILAAQRAAGGGLSMQDDGGGSGYGSGVGGDAQVHLPQLANVLPDRAELQLQELRKFQANLDDHISKERQAMVTGRVRRTSVLEELATGAQQPRWQMTYNTEQQASHAKLGAVDPNRRSEMDNARLARIAKDSRSSGMSAASASPVVARARRLSSVMGS</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2023-02-22" version="6" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BCZ6</accession>
    <name>A0A836BCZ6_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="2">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="2" type="ORF">HYH02_001239</name>
    </gene>
    <organism evidence="2 3">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="2" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="2">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="2">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454205.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BCZ6"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <dbReference type="Gene3D" id="1.20.1270.70">
        <property type="entry name" value="Designed single chain three-helix bundle"/>
        <property type="match status" value="1"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="1" id="KW-0175">Coiled coil</keyword>
    <keyword evidence="3" id="KW-1185">Reference proteome</keyword>
    <feature type="coiled-coil region" evidence="1">
        <location>
            <begin position="3"/>
            <end position="30"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="Coils"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="2">
        <source>
            <dbReference type="EMBL" id="KAG2454205.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="77" mass="8218" checksum="D0A389932C513FA0" modified="2021-09-29" version="1">MKVNTLEVKVDRLEADVKGLSTKADALSRIEGKLDALTSSGVKLKQIWMLQVAGGSRSRLWPGASLDGQLAVGMALH</sequence>
</entry>
<entry dataset="TrEMBL" created="2021-09-29" modified="2026-01-28" version="8" xmlns="https://uniprot.org/uniprot">
    <accession>A0A836BD88</accession>
    <name>A0A836BD88_9CHLO</name>
    <protein>
        <submittedName>
            <fullName evidence="3">Uncharacterized protein</fullName>
        </submittedName>
    </protein>
    <gene>
        <name evidence="3" type="ORF">HYH02_001449</name>
    </gene>
    <organism evidence="3 4">
        <name type="scientific">Chlamydomonas schloesseri</name>
        <dbReference type="NCBI Taxonomy" id="2026947"/>
        <lineage>
            <taxon>Eukaryota</taxon>
            <taxon>Viridiplantae</taxon>
            <taxon>Chlorophyta</taxon>
            <taxon>core chlorophytes</taxon>
            <taxon>Chlorophyceae</taxon>
            <taxon>CS clade</taxon>
            <taxon>Chlamydomonadales</taxon>
            <taxon>Chlamydomonadaceae</taxon>
            <taxon>Chlamydomonas</taxon>
        </lineage>
    </organism>
    <reference evidence="3" key="1">
        <citation type="journal article" date="2020" name="bioRxiv" volume="0" first="0" last="0">
            <title>Comparative genomics of Chlamydomonas.</title>
            <authorList>
                <person name="Craig R.J."/>
                <person name="Hasan A.R."/>
                <person name="Ness R.W."/>
                <person name="Keightley P.D."/>
            </authorList>
        </citation>
        <scope>NUCLEOTIDE SEQUENCE</scope>
        <source>
            <strain evidence="3">CCAP 11/173</strain>
        </source>
    </reference>
    <comment type="caution">
        <text evidence="3">The sequence shown here is derived from an EMBL/GenBank/DDBJ whole genome shotgun (WGS) entry which is preliminary data.</text>
    </comment>
    <dbReference type="EMBL" id="JAEHOD010000002">
        <property type="protein sequence ID" value="KAG2454430.1"/>
        <property type="molecule type" value="Genomic_DNA"/>
    </dbReference>
    <dbReference type="AlphaFoldDB" id="A0A836BD88"/>
    <dbReference type="OrthoDB" id="533856at2759"/>
    <dbReference type="Proteomes" id="UP000613740">
        <property type="component" value="Unassembled WGS sequence"/>
    </dbReference>
    <proteinExistence type="predicted"/>
    <keyword evidence="2" id="KW-0472">Membrane</keyword>
    <keyword evidence="4" id="KW-1185">Reference proteome</keyword>
    <keyword evidence="2" id="KW-0812">Transmembrane</keyword>
    <keyword evidence="2" id="KW-1133">Transmembrane helix</keyword>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="91"/>
            <end position="110"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="122"/>
            <end position="144"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="165"/>
            <end position="184"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="190"/>
            <end position="212"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="242"/>
            <end position="261"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="281"/>
            <end position="300"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="321"/>
            <end position="342"/>
        </location>
    </feature>
    <feature type="transmembrane region" description="Helical" evidence="2">
        <location>
            <begin position="348"/>
            <end position="366"/>
        </location>
    </feature>
    <feature type="region of interest" description="Disordered" evidence="1">
        <location>
            <begin position="46"/>
            <end position="78"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Low complexity" evidence="1">
        <location>
            <begin position="49"/>
            <end position="61"/>
        </location>
    </feature>
    <feature type="compositionally biased region" description="Pro residues" evidence="1">
        <location>
            <begin position="62"/>
            <end position="74"/>
        </location>
    </feature>
    <evidence type="ECO:0000256" key="1">
        <source>
            <dbReference type="SAM" id="MobiDB-lite"/>
        </source>
    </evidence>
    <evidence type="ECO:0000256" key="2">
        <source>
            <dbReference type="SAM" id="Phobius"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="3">
        <source>
            <dbReference type="EMBL" id="KAG2454430.1"/>
        </source>
    </evidence>
    <evidence type="ECO:0000313" key="4">
        <source>
            <dbReference type="Proteomes" id="UP000613740"/>
        </source>
    </evidence>
    <sequence length="372" mass="37666" checksum="1232A737E9BE10E4" modified="2021-09-29" version="1">MMISATSSQTRGLRAAAYGARAAGHPLVVVGRKPCKPVCFKEKDSIDETTTTPTPAKKSPPSSIPTPGAIPSPMPLETSTRPVNLGPVATTLYPALQYATIAAAAAAIIAPGPTGSALFRGAAMTPTNCALLVWAAAALIPSIISKRQIKKAADSGILGSPALKQLVSGCLLSGVLSLVVLTQAISLRNPVLTCTVGTLAGVATLTTAYTLVKIRESGQLLPSPRGLLGGALDLLTPRNATAAGYSVLAAATAAAGVALFTSDPATACPVFYQTKDAIHVFGSRIAGALTLGAAVSLFTIKHAADDGRQGSPMYKQLNGAAAAWAGLTAGVIGYSIATGLAMSTPVTLGFLTYYIITATFTGYNWATAPKTA</sequence>
</entry>
<copyright>
Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms Distributed under the Creative Commons Attribution (CC BY 4.0) License
</copyright>
</uniprot>