[M::bwa_idx_load_from_disk] read 3171 ALT contigs [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1035491, 72, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (292, 334, 420) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (36, 676) [M::mem_pestat] mean and std.dev: (313.14, 87.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 804) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (762, 2591, 3579) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9213) [M::mem_pestat] mean and std.dev: (2773.01, 2422.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12464) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (386, 915, 1527) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3809) [M::mem_pestat] mean and std.dev: (848.10, 591.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4950) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1284.758 CPU sec, 76.154 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036481, 65, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (278, 323, 407) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (20, 665) [M::mem_pestat] mean and std.dev: (283.80, 109.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 794) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1614, 2592, 3001) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5775) [M::mem_pestat] mean and std.dev: (1988.29, 1131.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7162) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (439, 1231, 2338) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6136) [M::mem_pestat] mean and std.dev: (1424.35, 1268.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8035) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1238.247 CPU sec, 56.966 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036096, 62, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (244, 307, 354) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 574) [M::mem_pestat] mean and std.dev: (261.45, 110.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 705) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1470, 2590, 2631) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4953) [M::mem_pestat] mean and std.dev: (1981.29, 1165.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6644) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (346, 385, 590) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1078) [M::mem_pestat] mean and std.dev: (396.00, 141.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1322) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1240.664 CPU sec, 69.187 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036315, 51, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (237, 331, 369) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 633) [M::mem_pestat] mean and std.dev: (271.69, 123.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 766) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (491, 1923, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6866) [M::mem_pestat] mean and std.dev: (1701.81, 1303.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8991) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (433, 978, 1815) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4579) [M::mem_pestat] mean and std.dev: (1279.41, 982.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5961) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.131 CPU sec, 53.932 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035933, 72, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (286, 331, 395) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (68, 613) [M::mem_pestat] mean and std.dev: (311.95, 95.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 722) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (260, 1645, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7322) [M::mem_pestat] mean and std.dev: (1659.99, 1481.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9676) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (457, 1191, 2038) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5200) [M::mem_pestat] mean and std.dev: (1455.25, 1110.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6781) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1232.305 CPU sec, 66.492 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036152, 49, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (291, 328, 400) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (73, 618) [M::mem_pestat] mean and std.dev: (318.07, 95.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 727) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (450, 2590, 2620) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6960) [M::mem_pestat] mean and std.dev: (2031.93, 1577.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9130) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (365, 805, 1775) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4595) [M::mem_pestat] mean and std.dev: (951.96, 738.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6005) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1222.720 CPU sec, 53.756 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1036646, 59, 32) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (253, 343, 413) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733) [M::mem_pestat] mean and std.dev: (298.89, 110.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 893) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (287, 1920, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7259) [M::mem_pestat] mean and std.dev: (1634.91, 1307.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9583) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (410, 850, 1471) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3593) [M::mem_pestat] mean and std.dev: (991.60, 816.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4654) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1273.740 CPU sec, 75.620 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036347, 51, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (308, 335, 608) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1208) [M::mem_pestat] mean and std.dev: (384.33, 188.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1508) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1069, 2182, 2935) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6667) [M::mem_pestat] mean and std.dev: (1866.39, 1398.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8533) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (871, 1575, 2731) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6451) [M::mem_pestat] mean and std.dev: (1573.81, 1026.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8311) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1244.550 CPU sec, 56.941 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1036039, 67, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (159, 264, 336) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690) [M::mem_pestat] mean and std.dev: (244.79, 129.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (688, 2591, 2971) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7537) [M::mem_pestat] mean and std.dev: (2139.24, 1733.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9820) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (445, 1012, 2424) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6382) [M::mem_pestat] mean and std.dev: (1438.84, 1359.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8361) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1247.787 CPU sec, 69.005 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035913, 70, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (279, 339, 639) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1359) [M::mem_pestat] mean and std.dev: (378.20, 232.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1719) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (456, 2599, 2625) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6963) [M::mem_pestat] mean and std.dev: (1954.00, 1461.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9132) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (377, 1227, 1899) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4943) [M::mem_pestat] mean and std.dev: (1253.56, 996.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6465) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1224.938 CPU sec, 54.182 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1035996, 64, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (212, 338, 533) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1175) [M::mem_pestat] mean and std.dev: (312.50, 200.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1496) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (926, 2596, 3644) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9080) [M::mem_pestat] mean and std.dev: (2852.49, 2602.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13264) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (477, 1617, 3025) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8121) [M::mem_pestat] mean and std.dev: (1578.19, 1298.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10669) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1242.053 CPU sec, 68.592 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1035178, 68, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (287, 329, 389) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (83, 593) [M::mem_pestat] mean and std.dev: (315.75, 64.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 695) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1038, 2376, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5775) [M::mem_pestat] mean and std.dev: (1878.08, 1197.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7354) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (483, 1033, 4461) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12417) [M::mem_pestat] mean and std.dev: (1983.76, 2364.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16395) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1229.902 CPU sec, 54.367 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036499, 70, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (237, 321, 370) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636) [M::mem_pestat] mean and std.dev: (276.95, 113.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 769) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (432, 2480, 2607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6957) [M::mem_pestat] mean and std.dev: (1719.65, 1138.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9132) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (297, 418, 1088) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2670) [M::mem_pestat] mean and std.dev: (592.06, 487.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3461) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1290.359 CPU sec, 76.545 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1036344, 77, 13) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (214, 297, 369) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 679) [M::mem_pestat] mean and std.dev: (258.29, 104.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 834) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (542, 2595, 2807) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7337) [M::mem_pestat] mean and std.dev: (1832.06, 1240.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9602) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (435, 1067, 3059) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8307) [M::mem_pestat] mean and std.dev: (1679.23, 1478.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10931) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1245.420 CPU sec, 56.714 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035665, 70, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 326, 365) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (50, 575) [M::mem_pestat] mean and std.dev: (282.05, 106.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 707) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (576, 2593, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6690) [M::mem_pestat] mean and std.dev: (1843.68, 1173.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8728) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (798, 1226, 1853) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3963) [M::mem_pestat] mean and std.dev: (1150.06, 600.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5018) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1241.561 CPU sec, 66.949 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036269, 53, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (237, 291, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663) [M::mem_pestat] mean and std.dev: (273.98, 135.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 816) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1476, 2599, 3630) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7938) [M::mem_pestat] mean and std.dev: (2079.67, 1384.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10092) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (465, 1167, 2176) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5598) [M::mem_pestat] mean and std.dev: (1620.29, 1452.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7429) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.646 CPU sec, 53.534 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 1036504, 68, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (284, 335, 444) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 764) [M::mem_pestat] mean and std.dev: (300.30, 124.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 924) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (130, 2589, 2647) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7681) [M::mem_pestat] mean and std.dev: (1722.85, 1570.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10198) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (430, 964, 2511) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6673) [M::mem_pestat] mean and std.dev: (1168.81, 884.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8754) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1246.383 CPU sec, 70.130 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035085, 55, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (192, 332, 587) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1377) [M::mem_pestat] mean and std.dev: (347.00, 299.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1772) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.85) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1421, 2599, 2956) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6026) [M::mem_pestat] mean and std.dev: (2178.51, 1441.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7944) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (372, 516, 1480) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3696) [M::mem_pestat] mean and std.dev: (928.38, 766.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4804) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1228.677 CPU sec, 54.212 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1036050, 58, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (255, 328, 425) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765) [M::mem_pestat] mean and std.dev: (288.96, 107.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 935) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (127, 2590, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7588) [M::mem_pestat] mean and std.dev: (1777.53, 1653.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10075) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (351, 438, 1698) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4392) [M::mem_pestat] mean and std.dev: (942.79, 926.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5739) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1237.414 CPU sec, 64.136 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 1035144, 68, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (199, 340, 507) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1123) [M::mem_pestat] mean and std.dev: (302.30, 193.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1431) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.34, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (287, 1938, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7244) [M::mem_pestat] mean and std.dev: (1622.77, 1316.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9563) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (524, 1238, 2058) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5126) [M::mem_pestat] mean and std.dev: (1314.52, 956.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6660) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1271.407 CPU sec, 78.533 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036856, 64, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (287, 331, 464) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 818) [M::mem_pestat] mean and std.dev: (320.15, 121.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 995) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (351, 1911, 2608) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7122) [M::mem_pestat] mean and std.dev: (1612.34, 1499.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9379) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (395, 910, 1397) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3401) [M::mem_pestat] mean and std.dev: (999.95, 706.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4403) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1235.944 CPU sec, 54.965 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036031, 68, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (202, 330, 418) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 850) [M::mem_pestat] mean and std.dev: (274.86, 154.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1066) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (654, 2598, 2625) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6567) [M::mem_pestat] mean and std.dev: (2030.94, 1422.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8538) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (371, 1001, 1395) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3443) [M::mem_pestat] mean and std.dev: (1075.80, 847.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4467) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1243.634 CPU sec, 68.725 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035643, 69, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (211, 317, 375) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (272.86, 128.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1471, 2596, 2698) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5152) [M::mem_pestat] mean and std.dev: (1995.73, 1246.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6983) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (360, 451, 1708) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4404) [M::mem_pestat] mean and std.dev: (1045.50, 1025.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5752) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1241.083 CPU sec, 54.673 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035772, 58, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (287, 333, 371) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (119, 539) [M::mem_pestat] mean and std.dev: (302.24, 67.38) [M::mem_pestat] low and high boundaries for proper pairs: (33, 623) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (586, 2595, 2624) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6700) [M::mem_pestat] mean and std.dev: (1997.09, 1280.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8738) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (366, 424, 1298) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3162) [M::mem_pestat] mean and std.dev: (707.95, 579.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4094) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1243.800 CPU sec, 70.205 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035971, 52, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (270, 342, 678) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1494) [M::mem_pestat] mean and std.dev: (381.61, 267.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1902) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (256, 2583, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7324) [M::mem_pestat] mean and std.dev: (1662.85, 1274.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9680) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (345, 443, 933) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2109) [M::mem_pestat] mean and std.dev: (537.00, 425.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2697) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1230.339 CPU sec, 54.153 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 1036291, 66, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (255, 325, 395) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675) [M::mem_pestat] mean and std.dev: (289.18, 119.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 815) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (115, 1906, 2603) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7579) [M::mem_pestat] mean and std.dev: (1378.92, 1252.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10067) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (385, 796, 1212) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2866) [M::mem_pestat] mean and std.dev: (841.94, 563.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3693) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1281.203 CPU sec, 76.171 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035873, 51, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (258, 300, 688) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1548) [M::mem_pestat] mean and std.dev: (383.77, 330.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1978) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (565, 2601, 2945) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7705) [M::mem_pestat] mean and std.dev: (2190.55, 1600.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10085) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (418, 903, 1379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3301) [M::mem_pestat] mean and std.dev: (1027.57, 706.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4262) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1261.467 CPU sec, 57.751 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1035655, 66, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (254, 325, 395) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 677) [M::mem_pestat] mean and std.dev: (264.68, 112.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 818) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (267, 1724, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7308) [M::mem_pestat] mean and std.dev: (1489.90, 1351.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9655) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (403, 1522, 2085) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5449) [M::mem_pestat] mean and std.dev: (1140.62, 891.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7131) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1242.771 CPU sec, 70.953 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036392, 68, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (266, 324, 387) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 629) [M::mem_pestat] mean and std.dev: (275.82, 89.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 750) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (802, 2583, 2618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6250) [M::mem_pestat] mean and std.dev: (1870.08, 1217.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8066) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (724, 944, 1407) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2773) [M::mem_pestat] mean and std.dev: (916.95, 514.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3456) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.606 CPU sec, 54.256 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1035883, 68, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 313, 363) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (66, 561) [M::mem_pestat] mean and std.dev: (285.88, 57.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 660) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (390, 2586, 2834) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7722) [M::mem_pestat] mean and std.dev: (1947.76, 1610.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10166) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (383, 882, 1314) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3176) [M::mem_pestat] mean and std.dev: (941.88, 748.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4107) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1244.368 CPU sec, 67.492 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 1036117, 66, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (278, 327, 402) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (30, 650) [M::mem_pestat] mean and std.dev: (287.18, 103.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 774) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (621, 2597, 2626) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6636) [M::mem_pestat] mean and std.dev: (1849.60, 1227.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8641) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (438, 1224, 1547) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3765) [M::mem_pestat] mean and std.dev: (1040.00, 570.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4874) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1230.174 CPU sec, 54.205 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 1035865, 59, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (276, 339, 446) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 786) [M::mem_pestat] mean and std.dev: (279.23, 113.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 956) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (427, 2522, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6976) [M::mem_pestat] mean and std.dev: (1720.94, 1258.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9159) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (816, 1854, 3032) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7464) [M::mem_pestat] mean and std.dev: (2556.55, 2239.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11513) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1243.229 CPU sec, 65.054 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035923, 65, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (271, 335, 772) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1774) [M::mem_pestat] mean and std.dev: (358.66, 240.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2275) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1182, 2064, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5466) [M::mem_pestat] mean and std.dev: (2013.90, 1357.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7446) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (572, 1398, 1850) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4406) [M::mem_pestat] mean and std.dev: (1371.39, 935.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5684) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 2666668 sequences (240000120 bp)... [M::mem_process_seqs] Processed 2666668 reads in 1257.233 CPU sec, 76.782 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1036603, 67, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (229, 318, 373) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661) [M::mem_pestat] mean and std.dev: (254.11, 116.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 805) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (578, 2597, 2915) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7589) [M::mem_pestat] mean and std.dev: (2036.52, 1490.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9926) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (374, 1103, 2975) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8177) [M::mem_pestat] mean and std.dev: (1533.00, 1333.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10778) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1233.115 CPU sec, 55.063 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 1036172, 51, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (185, 335, 417) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 881) [M::mem_pestat] mean and std.dev: (301.80, 177.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1113) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (328, 1890, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7177) [M::mem_pestat] mean and std.dev: (1553.73, 1249.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9460) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (320, 944, 2524) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6932) [M::mem_pestat] mean and std.dev: (1254.28, 1148.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9136) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 2666668 sequences (240000120 bp)... [M::mem_process_seqs] Processed 2666668 reads in 1252.988 CPU sec, 71.015 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036006, 68, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (253, 328, 369) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (21, 601) [M::mem_pestat] mean and std.dev: (276.84, 96.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 717) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (303, 1902, 2848) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7938) [M::mem_pestat] mean and std.dev: (1818.31, 1716.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10483) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (566, 1109, 1713) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4007) [M::mem_pestat] mean and std.dev: (1127.17, 849.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5154) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1236.756 CPU sec, 54.755 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1035797, 62, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (296, 357, 856) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1976) [M::mem_pestat] mean and std.dev: (517.04, 444.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2536) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (161, 1922, 2600) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7478) [M::mem_pestat] mean and std.dev: (1616.60, 1500.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9917) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (320, 766, 1463) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3749) [M::mem_pestat] mean and std.dev: (863.15, 646.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4892) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 2666668 sequences (240000120 bp)... [M::mem_process_seqs] Processed 2666668 reads in 1248.471 CPU sec, 70.637 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 1035697, 60, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 304, 356) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (29, 574) [M::mem_pestat] mean and std.dev: (266.03, 86.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 683) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (344, 2089, 3519) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9869) [M::mem_pestat] mean and std.dev: (2436.08, 2473.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13044) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (388, 756, 1706) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4342) [M::mem_pestat] mean and std.dev: (1172.35, 1141.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5739) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1232.901 CPU sec, 54.315 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035999, 74, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (212, 304, 384) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 728) [M::mem_pestat] mean and std.dev: (256.89, 118.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 900) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (517, 2578, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6808) [M::mem_pestat] mean and std.dev: (1870.55, 1314.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8905) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (324, 1039, 1732) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4548) [M::mem_pestat] mean and std.dev: (1041.85, 873.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5956) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1291.592 CPU sec, 76.440 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 1036354, 50, 29) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (232, 323, 392) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 712) [M::mem_pestat] mean and std.dev: (268.78, 105.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 872) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (586, 2573, 3396) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9016) [M::mem_pestat] mean and std.dev: (2794.26, 2547.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12983) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (315, 719, 1341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3393) [M::mem_pestat] mean and std.dev: (730.07, 569.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4419) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1254.461 CPU sec, 57.350 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036328, 66, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 329, 452) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 836) [M::mem_pestat] mean and std.dev: (281.34, 92.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1028) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.42, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (655, 2578, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6526) [M::mem_pestat] mean and std.dev: (1783.32, 1222.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8483) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (370, 451, 1173) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2779) [M::mem_pestat] mean and std.dev: (846.68, 756.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3872) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1238.946 CPU sec, 70.231 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035314, 69, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (315, 336, 392) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (161, 546) [M::mem_pestat] mean and std.dev: (326.34, 50.20) [M::mem_pestat] low and high boundaries for proper pairs: (84, 623) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (274, 2292, 3141) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8875) [M::mem_pestat] mean and std.dev: (2309.67, 2221.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11742) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (515, 1231, 2491) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6443) [M::mem_pestat] mean and std.dev: (1416.13, 1290.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8419) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1248.140 CPU sec, 55.380 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 1035955, 71, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (291, 327, 390) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (93, 588) [M::mem_pestat] mean and std.dev: (304.33, 79.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 687) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (430, 1915, 2934) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7942) [M::mem_pestat] mean and std.dev: (1876.58, 1656.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10446) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (389, 1001, 1773) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4541) [M::mem_pestat] mean and std.dev: (1151.96, 1027.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5925) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1253.941 CPU sec, 68.251 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035600, 53, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (265, 329, 436) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 778) [M::mem_pestat] mean and std.dev: (301.51, 119.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 949) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (366, 1644, 2607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7089) [M::mem_pestat] mean and std.dev: (1572.08, 1327.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9330) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (335, 951, 1484) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3782) [M::mem_pestat] mean and std.dev: (758.56, 551.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4931) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1224.180 CPU sec, 53.922 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035986, 66, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 299, 372) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (48, 588) [M::mem_pestat] mean and std.dev: (272.64, 95.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 696) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (322, 2589, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7201) [M::mem_pestat] mean and std.dev: (2026.35, 1548.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9494) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (390, 890, 2803) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7629) [M::mem_pestat] mean and std.dev: (2002.06, 2270.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11084) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1238.877 CPU sec, 63.356 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036671, 45, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (281, 334, 415) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (13, 683) [M::mem_pestat] mean and std.dev: (306.60, 105.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 817) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (737, 2590, 2624) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6398) [M::mem_pestat] mean and std.dev: (1871.15, 1345.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8285) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (433, 1509, 1858) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4708) [M::mem_pestat] mean and std.dev: (1136.76, 714.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6133) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1272.278 CPU sec, 78.685 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1035604, 71, 32) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (236, 332, 485) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 983) [M::mem_pestat] mean and std.dev: (303.41, 167.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1232) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1211, 2591, 2628) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5462) [M::mem_pestat] mean and std.dev: (1969.22, 1264.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7029) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (368, 1067, 1900) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4964) [M::mem_pestat] mean and std.dev: (1179.20, 998.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6496) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1231.925 CPU sec, 55.155 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035481, 63, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (239, 315, 436) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 830) [M::mem_pestat] mean and std.dev: (268.60, 138.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1027) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (335, 1609, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7166) [M::mem_pestat] mean and std.dev: (1625.35, 1329.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9443) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (304, 773, 1784) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4744) [M::mem_pestat] mean and std.dev: (950.47, 872.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6224) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 2666668 sequences (240000120 bp)... [M::mem_process_seqs] Processed 2666668 reads in 1249.428 CPU sec, 72.285 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1035610, 74, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (224, 341, 1170) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3062) [M::mem_pestat] mean and std.dev: (572.86, 623.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4008) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (338, 2577, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7163) [M::mem_pestat] mean and std.dev: (1728.28, 1384.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9438) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (515, 1162, 1527) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3551) [M::mem_pestat] mean and std.dev: (1145.24, 761.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4563) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1232.137 CPU sec, 54.256 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1036734, 70, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (317, 358, 439) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (73, 683) [M::mem_pestat] mean and std.dev: (338.32, 83.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 805) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (133, 1899, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7573) [M::mem_pestat] mean and std.dev: (1572.58, 1415.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10053) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (972, 1239, 2341) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5079) [M::mem_pestat] mean and std.dev: (1180.89, 771.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6448) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1255.657 CPU sec, 69.840 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 1035913, 58, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (265, 311, 339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (117, 487) [M::mem_pestat] mean and std.dev: (299.32, 59.12) [M::mem_pestat] low and high boundaries for proper pairs: (43, 561) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (243, 2587, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7359) [M::mem_pestat] mean and std.dev: (1646.15, 1243.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9731) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (421, 1217, 1655) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4123) [M::mem_pestat] mean and std.dev: (1091.24, 629.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5357) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1227.283 CPU sec, 54.087 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036019, 59, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 337, 420) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 732) [M::mem_pestat] mean and std.dev: (289.38, 121.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 888) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (268, 2588, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7297) [M::mem_pestat] mean and std.dev: (1779.84, 1322.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9640) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (384, 1263, 2063) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5421) [M::mem_pestat] mean and std.dev: (1424.21, 1201.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7100) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1294.338 CPU sec, 77.195 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1036107, 51, 12) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (179, 318, 378) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 776) [M::mem_pestat] mean and std.dev: (263.71, 135.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 975) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (140, 1908, 2605) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7535) [M::mem_pestat] mean and std.dev: (1721.79, 1655.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10000) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (472, 790, 1543) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3685) [M::mem_pestat] mean and std.dev: (1136.50, 1020.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5218) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1242.594 CPU sec, 56.808 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035442, 70, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (169, 309, 492) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1138) [M::mem_pestat] mean and std.dev: (329.52, 259.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1461) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (335, 2573, 2640) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7250) [M::mem_pestat] mean and std.dev: (1679.41, 1432.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9555) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (701, 1170, 1765) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3893) [M::mem_pestat] mean and std.dev: (1121.64, 631.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4957) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1244.423 CPU sec, 67.763 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1035549, 60, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (282, 340, 533) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1035) [M::mem_pestat] mean and std.dev: (389.11, 229.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1308) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (350, 2319, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7139) [M::mem_pestat] mean and std.dev: (1767.95, 1233.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9402) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (307, 1230, 3648) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10330) [M::mem_pestat] mean and std.dev: (1907.69, 1928.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13671) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1225.098 CPU sec, 53.987 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036311, 70, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (235, 343, 659) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1507) [M::mem_pestat] mean and std.dev: (451.02, 376.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1956) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (592, 2598, 2855) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7381) [M::mem_pestat] mean and std.dev: (1941.48, 1279.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9644) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (743, 1306, 1818) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3968) [M::mem_pestat] mean and std.dev: (1170.00, 677.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5043) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1240.673 CPU sec, 70.216 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036862, 54, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (238, 343, 429) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 811) [M::mem_pestat] mean and std.dev: (282.73, 113.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1002) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (174, 2587, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7500) [M::mem_pestat] mean and std.dev: (1760.75, 1463.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9942) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (385, 624, 1332) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3226) [M::mem_pestat] mean and std.dev: (916.19, 686.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4173) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.949 CPU sec, 54.181 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035568, 71, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (273, 326, 398) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (23, 648) [M::mem_pestat] mean and std.dev: (298.55, 100.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 773) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (711, 2577, 2628) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6462) [M::mem_pestat] mean and std.dev: (1653.10, 1187.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8379) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (641, 1123, 1540) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3338) [M::mem_pestat] mean and std.dev: (853.19, 431.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4237) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1247.568 CPU sec, 62.934 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1036077, 68, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (250, 337, 396) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688) [M::mem_pestat] mean and std.dev: (296.93, 108.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 834) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (409, 2582, 2917) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7933) [M::mem_pestat] mean and std.dev: (1989.28, 1854.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10441) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (448, 1126, 1825) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4579) [M::mem_pestat] mean and std.dev: (1346.89, 1033.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5956) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1263.018 CPU sec, 77.742 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1035468, 66, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (262, 347, 378) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (30, 610) [M::mem_pestat] mean and std.dev: (304.61, 119.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 782) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (467, 2592, 2927) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7847) [M::mem_pestat] mean and std.dev: (1979.11, 1410.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10307) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (404, 941, 1434) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3494) [M::mem_pestat] mean and std.dev: (872.83, 528.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4524) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1228.021 CPU sec, 55.406 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 1036562, 59, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 322, 388) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (25, 630) [M::mem_pestat] mean and std.dev: (287.78, 99.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 751) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (273, 1957, 2618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7308) [M::mem_pestat] mean and std.dev: (1739.16, 1372.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9653) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (487, 943, 1850) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4576) [M::mem_pestat] mean and std.dev: (1165.13, 984.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5939) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1232.099 CPU sec, 67.103 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035989, 61, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 341, 899) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2147) [M::mem_pestat] mean and std.dev: (527.04, 505.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2771) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1322, 2588, 2874) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5978) [M::mem_pestat] mean and std.dev: (1995.78, 1375.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7530) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (433, 1132, 1692) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4210) [M::mem_pestat] mean and std.dev: (1156.76, 873.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5469) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1222.973 CPU sec, 53.894 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1035940, 61, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (290, 310, 402) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (66, 626) [M::mem_pestat] mean and std.dev: (299.53, 87.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 738) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (923, 2588, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5993) [M::mem_pestat] mean and std.dev: (1976.21, 1345.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7683) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (241, 816, 1784) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4870) [M::mem_pestat] mean and std.dev: (884.43, 773.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6413) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1232.056 CPU sec, 67.656 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1035610, 65, 13) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (256, 321, 377) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (14, 619) [M::mem_pestat] mean and std.dev: (269.78, 92.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 740) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1038, 2591, 3166) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7422) [M::mem_pestat] mean and std.dev: (1933.34, 1303.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9550) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (334, 434, 1949) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5179) [M::mem_pestat] mean and std.dev: (876.00, 751.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6794) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.566 CPU sec, 54.048 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036218, 58, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (270, 331, 606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278) [M::mem_pestat] mean and std.dev: (377.11, 261.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1614) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (311, 2581, 2619) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7235) [M::mem_pestat] mean and std.dev: (1762.77, 1333.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9543) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (296, 433, 1466) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3806) [M::mem_pestat] mean and std.dev: (811.74, 782.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4976) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1262.969 CPU sec, 75.297 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 1035937, 71, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (308, 352, 957) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2255) [M::mem_pestat] mean and std.dev: (550.00, 450.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2904) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (307, 1936, 2619) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7243) [M::mem_pestat] mean and std.dev: (1614.06, 1382.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9555) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (411, 796, 1570) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3888) [M::mem_pestat] mean and std.dev: (976.83, 735.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5047) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1228.185 CPU sec, 56.293 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 1036135, 70, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (285, 341, 885) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2085) [M::mem_pestat] mean and std.dev: (448.06, 339.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2685) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.80) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (183, 2017, 2602) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7440) [M::mem_pestat] mean and std.dev: (1593.79, 1424.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9859) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (402, 1171, 3230) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8886) [M::mem_pestat] mean and std.dev: (1846.52, 1858.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11714) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1232.283 CPU sec, 70.156 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036054, 61, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (203, 311, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731) [M::mem_pestat] mean and std.dev: (253.98, 115.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 907) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (273, 2582, 2838) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7968) [M::mem_pestat] mean and std.dev: (1835.66, 1704.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10533) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (347, 458, 1240) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3026) [M::mem_pestat] mean and std.dev: (770.59, 680.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3919) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.523 CPU sec, 53.733 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 1035845, 55, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (274, 326, 410) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (2, 682) [M::mem_pestat] mean and std.dev: (295.06, 83.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 818) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (830, 2599, 2990) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7310) [M::mem_pestat] mean and std.dev: (2164.72, 1387.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9470) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (381, 993, 1946) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5076) [M::mem_pestat] mean and std.dev: (1097.95, 811.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6641) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.440 CPU sec, 69.485 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035545, 65, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 322, 395) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777) [M::mem_pestat] mean and std.dev: (291.19, 121.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 968) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1422, 2593, 2979) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6093) [M::mem_pestat] mean and std.dev: (2060.64, 1326.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7650) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (334, 521, 1622) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4198) [M::mem_pestat] mean and std.dev: (819.79, 890.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5486) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.124 CPU sec, 53.669 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1036127, 62, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (282, 339, 614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1278) [M::mem_pestat] mean and std.dev: (381.61, 217.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1610) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1250, 2589, 2620) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5360) [M::mem_pestat] mean and std.dev: (1926.84, 1174.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6730) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (331, 1005, 1748) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4582) [M::mem_pestat] mean and std.dev: (1097.68, 880.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5999) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1223.585 CPU sec, 61.841 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 1035935, 68, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (291, 338, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 837) [M::mem_pestat] mean and std.dev: (324.57, 139.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1019) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (389, 2590, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7064) [M::mem_pestat] mean and std.dev: (1814.33, 1297.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9289) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (365, 1232, 1811) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4703) [M::mem_pestat] mean and std.dev: (1039.47, 727.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6149) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1237.156 CPU sec, 77.163 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036558, 66, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (252, 322, 408) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720) [M::mem_pestat] mean and std.dev: (272.09, 105.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 876) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1475, 2591, 2829) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5537) [M::mem_pestat] mean and std.dev: (1955.60, 1151.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6891) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (366, 1098, 1820) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4728) [M::mem_pestat] mean and std.dev: (988.94, 919.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6182) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.218 CPU sec, 54.666 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035702, 56, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 304, 401) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 709) [M::mem_pestat] mean and std.dev: (273.64, 123.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 863) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (518, 2589, 2731) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7157) [M::mem_pestat] mean and std.dev: (1900.71, 1421.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9370) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (368, 1159, 2695) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7349) [M::mem_pestat] mean and std.dev: (1782.24, 1823.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9676) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.266 CPU sec, 67.535 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035309, 67, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (261, 330, 372) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (39, 594) [M::mem_pestat] mean and std.dev: (287.17, 100.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 705) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (644, 2590, 2840) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7232) [M::mem_pestat] mean and std.dev: (1870.30, 1222.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9428) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (308, 1122, 2084) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5636) [M::mem_pestat] mean and std.dev: (1223.38, 1024.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7412) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1212.183 CPU sec, 53.482 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036060, 69, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 318, 362) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (68, 558) [M::mem_pestat] mean and std.dev: (281.72, 76.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 656) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (392, 2592, 2639) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7133) [M::mem_pestat] mean and std.dev: (1955.74, 1357.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9380) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (416, 1334, 1940) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4988) [M::mem_pestat] mean and std.dev: (1183.70, 746.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6512) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1233.621 CPU sec, 70.191 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035810, 67, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (266, 329, 370) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (58, 578) [M::mem_pestat] mean and std.dev: (290.32, 94.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 682) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (383, 2587, 3154) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8696) [M::mem_pestat] mean and std.dev: (2631.97, 2666.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13299) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (375, 715, 1614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4092) [M::mem_pestat] mean and std.dev: (962.75, 805.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5331) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.620 CPU sec, 53.247 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1035826, 69, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (262, 305, 364) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (58, 568) [M::mem_pestat] mean and std.dev: (278.91, 75.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 670) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (281, 2594, 2905) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8153) [M::mem_pestat] mean and std.dev: (1964.54, 1486.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10777) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (373, 1709, 3435) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9559) [M::mem_pestat] mean and std.dev: (2060.12, 1732.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12621) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1265.051 CPU sec, 75.890 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035232, 52, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (199, 299, 362) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688) [M::mem_pestat] mean and std.dev: (259.96, 100.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 851) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (607, 2596, 3495) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9271) [M::mem_pestat] mean and std.dev: (2924.12, 2789.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14083) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (306, 511, 1566) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4086) [M::mem_pestat] mean and std.dev: (861.84, 735.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5346) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1230.272 CPU sec, 56.372 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1036059, 78, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (299, 340, 821) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1865) [M::mem_pestat] mean and std.dev: (466.48, 375.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2387) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (268, 2593, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7297) [M::mem_pestat] mean and std.dev: (1770.57, 1262.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9640) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (357, 849, 1240) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3006) [M::mem_pestat] mean and std.dev: (833.84, 706.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3889) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 2666668 sequences (240000120 bp)... [M::mem_process_seqs] Processed 2666668 reads in 1236.437 CPU sec, 71.236 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 1036311, 76, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (231, 312, 409) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 765) [M::mem_pestat] mean and std.dev: (278.22, 142.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 943) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (236, 1910, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7364) [M::mem_pestat] mean and std.dev: (1663.29, 1479.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9740) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (458, 1222, 1604) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3896) [M::mem_pestat] mean and std.dev: (1005.57, 642.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5042) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.010 CPU sec, 53.323 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035581, 50, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (285, 352, 717) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1581) [M::mem_pestat] mean and std.dev: (445.84, 347.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2013) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (561, 2597, 2937) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7689) [M::mem_pestat] mean and std.dev: (2062.64, 1642.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10065) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (288, 394, 1744) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4656) [M::mem_pestat] mean and std.dev: (909.04, 1010.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6112) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.473 CPU sec, 65.717 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035639, 60, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (255, 316, 383) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 639) [M::mem_pestat] mean and std.dev: (276.33, 101.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 767) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (516, 2571, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6807) [M::mem_pestat] mean and std.dev: (1922.22, 1357.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8904) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (475, 909, 1941) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4873) [M::mem_pestat] mean and std.dev: (1304.50, 1268.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6379) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.457 CPU sec, 53.172 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035567, 69, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (249, 309, 369) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (9, 609) [M::mem_pestat] mean and std.dev: (278.61, 89.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 729) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (141, 1621, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7545) [M::mem_pestat] mean and std.dev: (1493.49, 1597.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10013) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (362, 1129, 1794) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4658) [M::mem_pestat] mean and std.dev: (1134.00, 767.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6090) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.339 CPU sec, 60.807 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036570, 48, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (238, 306, 414) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 766) [M::mem_pestat] mean and std.dev: (259.25, 128.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 942) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1909, 2603, 2967) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5083) [M::mem_pestat] mean and std.dev: (2232.47, 1316.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7498) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (361, 1057, 1522) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3844) [M::mem_pestat] mean and std.dev: (1127.38, 839.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5005) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1253.339 CPU sec, 77.015 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035905, 61, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (240, 325, 464) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 912) [M::mem_pestat] mean and std.dev: (298.90, 156.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1136) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (340, 1901, 2605) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7135) [M::mem_pestat] mean and std.dev: (1482.98, 1168.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9400) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (390, 1083, 1654) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4182) [M::mem_pestat] mean and std.dev: (1167.39, 909.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5446) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1224.044 CPU sec, 55.313 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035761, 63, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (272, 322, 372) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (72, 572) [M::mem_pestat] mean and std.dev: (306.03, 65.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 672) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1074, 2576, 2982) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6798) [M::mem_pestat] mean and std.dev: (1989.00, 1540.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8706) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (428, 975, 1587) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3905) [M::mem_pestat] mean and std.dev: (866.88, 612.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5064) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1216.028 CPU sec, 66.962 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036068, 57, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (287, 351, 1130) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2816) [M::mem_pestat] mean and std.dev: (591.08, 580.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3659) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (337, 2581, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7156) [M::mem_pestat] mean and std.dev: (1888.50, 1433.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9429) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (329, 581, 1219) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2999) [M::mem_pestat] mean and std.dev: (773.29, 655.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3889) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.440 CPU sec, 53.372 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1036444, 65, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (262, 312, 378) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (30, 610) [M::mem_pestat] mean and std.dev: (297.25, 83.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 726) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (207, 2594, 2655) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7551) [M::mem_pestat] mean and std.dev: (1896.29, 1591.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9999) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (351, 617, 1080) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2538) [M::mem_pestat] mean and std.dev: (803.80, 650.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3406) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.993 CPU sec, 67.801 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1035273, 61, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (283, 317, 416) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (17, 682) [M::mem_pestat] mean and std.dev: (307.29, 78.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 815) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (373, 2590, 2975) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8179) [M::mem_pestat] mean and std.dev: (2252.48, 2079.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10781) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (323, 899, 1635) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4259) [M::mem_pestat] mean and std.dev: (970.20, 847.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5571) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.660 CPU sec, 53.515 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1036188, 65, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (261, 311, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (95, 510) [M::mem_pestat] mean and std.dev: (309.70, 72.64) [M::mem_pestat] low and high boundaries for proper pairs: (12, 600) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (222, 1913, 2619) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7413) [M::mem_pestat] mean and std.dev: (1675.67, 1357.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9810) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (378, 762, 1350) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3294) [M::mem_pestat] mean and std.dev: (929.81, 663.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4266) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1270.469 CPU sec, 76.184 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1036254, 65, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (279, 332, 434) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744) [M::mem_pestat] mean and std.dev: (284.38, 108.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 899) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (226, 1915, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7387) [M::mem_pestat] mean and std.dev: (1711.87, 1524.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9774) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (229, 547, 1477) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3973) [M::mem_pestat] mean and std.dev: (823.85, 696.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5221) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.408 CPU sec, 55.952 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036080, 55, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (300, 345, 443) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (14, 729) [M::mem_pestat] mean and std.dev: (299.02, 80.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 872) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (294, 1960, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7239) [M::mem_pestat] mean and std.dev: (1686.68, 1229.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9554) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (538, 1099, 1859) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4501) [M::mem_pestat] mean and std.dev: (1216.88, 797.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5822) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1214.617 CPU sec, 68.029 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1035851, 67, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 323, 372) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 622) [M::mem_pestat] mean and std.dev: (263.18, 103.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 747) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (429, 1697, 2959) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8019) [M::mem_pestat] mean and std.dev: (1763.78, 1421.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10549) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (414, 959, 1412) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3408) [M::mem_pestat] mean and std.dev: (847.56, 577.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4406) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.016 CPU sec, 53.517 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1036770, 66, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (216, 322, 376) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 696) [M::mem_pestat] mean and std.dev: (258.23, 102.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 856) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.85) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (234, 1927, 2964) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8424) [M::mem_pestat] mean and std.dev: (1899.92, 1788.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11154) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (372, 1003, 1386) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3414) [M::mem_pestat] mean and std.dev: (880.72, 546.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4428) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.113 CPU sec, 63.908 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1035378, 57, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (313, 352, 849) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1921) [M::mem_pestat] mean and std.dev: (455.50, 338.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2457) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (367, 2596, 2918) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8020) [M::mem_pestat] mean and std.dev: (1740.43, 1291.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10571) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (485, 999, 1592) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3806) [M::mem_pestat] mean and std.dev: (903.50, 647.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4913) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.218 CPU sec, 53.754 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 1035765, 65, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (282, 326, 363) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (120, 525) [M::mem_pestat] mean and std.dev: (309.69, 48.71) [M::mem_pestat] low and high boundaries for proper pairs: (39, 606) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (503, 2579, 2626) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6872) [M::mem_pestat] mean and std.dev: (1779.61, 1359.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8995) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (606, 1262, 1621) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3651) [M::mem_pestat] mean and std.dev: (1167.57, 733.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4666) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.169 CPU sec, 59.280 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036205, 55, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (232, 330, 398) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 730) [M::mem_pestat] mean and std.dev: (292.02, 123.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 896) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (770, 2600, 2955) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7325) [M::mem_pestat] mean and std.dev: (2105.56, 1518.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9510) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (351, 389, 1197) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2889) [M::mem_pestat] mean and std.dev: (741.79, 574.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3735) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1245.601 CPU sec, 77.213 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036142, 56, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (242, 336, 1165) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3011) [M::mem_pestat] mean and std.dev: (599.54, 606.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3934) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (269, 1916, 2625) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7337) [M::mem_pestat] mean and std.dev: (1691.19, 1242.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9693) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (374, 856, 1928) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5036) [M::mem_pestat] mean and std.dev: (1102.65, 920.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6590) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.449 CPU sec, 54.624 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036497, 67, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (203, 300, 368) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698) [M::mem_pestat] mean and std.dev: (258.94, 119.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 863) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (379, 2091, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7075) [M::mem_pestat] mean and std.dev: (1822.16, 1439.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9307) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (346, 628, 1494) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3790) [M::mem_pestat] mean and std.dev: (962.74, 930.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4938) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.030 CPU sec, 69.443 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1035802, 66, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (262, 347, 497) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 967) [M::mem_pestat] mean and std.dev: (300.80, 125.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1202) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (280, 2499, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7282) [M::mem_pestat] mean and std.dev: (1612.82, 1219.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9616) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (303, 652, 1311) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3327) [M::mem_pestat] mean and std.dev: (724.09, 561.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4335) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.999 CPU sec, 54.008 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036841, 68, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (246, 324, 376) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636) [M::mem_pestat] mean and std.dev: (279.94, 117.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 766) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (930, 2593, 2887) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6801) [M::mem_pestat] mean and std.dev: (2115.51, 1586.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8758) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (415, 1000, 1303) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3079) [M::mem_pestat] mean and std.dev: (866.91, 516.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3967) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.604 CPU sec, 64.758 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1035619, 54, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (279, 318, 383) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (71, 591) [M::mem_pestat] mean and std.dev: (296.38, 70.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 695) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (437, 2591, 2964) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8018) [M::mem_pestat] mean and std.dev: (1928.04, 1541.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10545) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (366, 1005, 1487) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3729) [M::mem_pestat] mean and std.dev: (1008.21, 828.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4850) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.483 CPU sec, 53.381 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036352, 64, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (292, 342, 422) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (32, 682) [M::mem_pestat] mean and std.dev: (291.09, 94.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 812) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1362, 2600, 2955) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6141) [M::mem_pestat] mean and std.dev: (1897.09, 1163.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7734) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (392, 927, 1364) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3308) [M::mem_pestat] mean and std.dev: (883.88, 510.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4280) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1268.716 CPU sec, 75.503 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1034977, 56, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (262, 314, 369) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (48, 583) [M::mem_pestat] mean and std.dev: (282.53, 91.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 690) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (932, 2601, 2989) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7103) [M::mem_pestat] mean and std.dev: (2045.00, 1366.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9160) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (384, 858, 1299) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3129) [M::mem_pestat] mean and std.dev: (837.62, 498.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4044) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.231 CPU sec, 55.341 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 1035629, 61, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (227, 317, 417) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 797) [M::mem_pestat] mean and std.dev: (279.84, 127.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 987) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (367, 2580, 3730) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10456) [M::mem_pestat] mean and std.dev: (2677.36, 2604.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13819) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (410, 1093, 1454) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3542) [M::mem_pestat] mean and std.dev: (936.92, 681.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4586) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1217.529 CPU sec, 68.995 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 1035743, 58, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (239, 333, 416) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 770) [M::mem_pestat] mean and std.dev: (288.30, 133.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 947) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (139, 2583, 2607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7543) [M::mem_pestat] mean and std.dev: (1739.98, 1328.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10011) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (377, 739, 1654) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4208) [M::mem_pestat] mean and std.dev: (916.05, 754.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5485) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1224.421 CPU sec, 54.284 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 1036159, 65, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (271, 320, 478) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 892) [M::mem_pestat] mean and std.dev: (309.53, 148.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1099) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1239, 2597, 2922) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6288) [M::mem_pestat] mean and std.dev: (2188.41, 1479.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8105) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (371, 463, 2323) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6227) [M::mem_pestat] mean and std.dev: (1277.60, 1264.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8179) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.252 CPU sec, 66.198 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1035426, 73, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (220, 307, 349) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607) [M::mem_pestat] mean and std.dev: (264.23, 97.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 736) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (244, 2311, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7354) [M::mem_pestat] mean and std.dev: (1768.90, 1220.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9724) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (474, 899, 1571) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3765) [M::mem_pestat] mean and std.dev: (906.40, 573.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4862) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.004 CPU sec, 53.302 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035206, 83, 32) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (235, 339, 527) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1111) [M::mem_pestat] mean and std.dev: (307.22, 178.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1403) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1173, 2595, 2880) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6294) [M::mem_pestat] mean and std.dev: (1997.89, 1331.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8001) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (465, 922, 2269) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5877) [M::mem_pestat] mean and std.dev: (1489.71, 1517.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7681) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.023 CPU sec, 59.118 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035477, 48, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (280, 326, 570) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1150) [M::mem_pestat] mean and std.dev: (377.62, 260.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1440) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1128, 2593, 3173) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7263) [M::mem_pestat] mean and std.dev: (1938.10, 1192.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9308) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (386, 1289, 2394) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6410) [M::mem_pestat] mean and std.dev: (1412.17, 1357.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8418) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1241.677 CPU sec, 78.298 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036846, 70, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (286, 330, 452) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784) [M::mem_pestat] mean and std.dev: (309.95, 90.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 950) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (369, 2596, 2628) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7146) [M::mem_pestat] mean and std.dev: (1701.81, 1274.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9405) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (408, 762, 1533) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3783) [M::mem_pestat] mean and std.dev: (1015.00, 671.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4908) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1214.922 CPU sec, 54.128 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035224, 67, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (262, 318, 356) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (74, 544) [M::mem_pestat] mean and std.dev: (284.66, 84.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 638) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1456, 2596, 3487) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7549) [M::mem_pestat] mean and std.dev: (1993.36, 1240.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9580) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (706, 1451, 1944) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4420) [M::mem_pestat] mean and std.dev: (1192.31, 650.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5658) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1225.255 CPU sec, 68.463 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1035266, 73, 29) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (258, 314, 396) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672) [M::mem_pestat] mean and std.dev: (280.06, 87.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 810) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (321, 1975, 3639) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10275) [M::mem_pestat] mean and std.dev: (2671.93, 2723.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13593) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (349, 1228, 2909) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8029) [M::mem_pestat] mean and std.dev: (1773.03, 1839.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10589) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1214.659 CPU sec, 53.513 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 1036044, 64, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (284, 322, 591) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1205) [M::mem_pestat] mean and std.dev: (367.50, 238.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1512) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (132, 1910, 2618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7590) [M::mem_pestat] mean and std.dev: (1554.46, 1643.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10076) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (373, 1155, 1986) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5212) [M::mem_pestat] mean and std.dev: (1084.65, 788.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6825) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1223.191 CPU sec, 66.908 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036358, 57, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (276, 341, 857) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2019) [M::mem_pestat] mean and std.dev: (448.83, 360.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2600) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (304, 1908, 2639) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7309) [M::mem_pestat] mean and std.dev: (1577.98, 1366.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9644) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (485, 1106, 1564) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3722) [M::mem_pestat] mean and std.dev: (1062.64, 703.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4801) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.517 CPU sec, 53.300 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 1036307, 56, 36) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (273, 350, 752) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710) [M::mem_pestat] mean and std.dev: (413.98, 362.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2189) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (223, 2171, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7372) [M::mem_pestat] mean and std.dev: (1780.09, 1439.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9755) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (311, 526, 1646) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4316) [M::mem_pestat] mean and std.dev: (905.15, 865.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5651) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1280.494 CPU sec, 75.900 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1036280, 75, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 334, 375) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (51, 591) [M::mem_pestat] mean and std.dev: (284.53, 92.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 699) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (470, 2592, 2650) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7010) [M::mem_pestat] mean and std.dev: (2070.47, 1455.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9190) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (540, 925, 1874) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4542) [M::mem_pestat] mean and std.dev: (977.11, 598.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5876) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1227.042 CPU sec, 56.670 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1036516, 52, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (263, 325, 569) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1181) [M::mem_pestat] mean and std.dev: (346.73, 212.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1487) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (279, 2588, 3235) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9147) [M::mem_pestat] mean and std.dev: (2706.00, 2721.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13593) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (477, 1428, 2912) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7782) [M::mem_pestat] mean and std.dev: (1794.48, 1772.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10217) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1224.876 CPU sec, 65.110 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035452, 66, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (237, 326, 417) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777) [M::mem_pestat] mean and std.dev: (283.14, 137.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 957) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1174, 2606, 2992) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6628) [M::mem_pestat] mean and std.dev: (2080.34, 1386.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8446) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (331, 693, 936) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2146) [M::mem_pestat] mean and std.dev: (586.85, 381.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2751) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1205.912 CPU sec, 53.151 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1035564, 61, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (273, 323, 374) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (71, 576) [M::mem_pestat] mean and std.dev: (295.02, 94.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 677) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (362, 2573, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7106) [M::mem_pestat] mean and std.dev: (1742.58, 1315.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9354) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (401, 1024, 1630) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4088) [M::mem_pestat] mean and std.dev: (1133.38, 971.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5317) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1222.308 CPU sec, 67.985 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1035288, 52, 30) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (265, 334, 485) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 925) [M::mem_pestat] mean and std.dev: (300.68, 118.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1145) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (533, 2597, 3476) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9362) [M::mem_pestat] mean and std.dev: (2271.67, 1722.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12305) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (399, 1085, 1647) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4143) [M::mem_pestat] mean and std.dev: (1088.32, 817.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5391) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1212.385 CPU sec, 53.552 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1035962, 53, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (241, 291, 369) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625) [M::mem_pestat] mean and std.dev: (277.43, 89.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 753) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (995, 2602, 3619) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8867) [M::mem_pestat] mean and std.dev: (2771.13, 2289.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11929) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (398, 1147, 1395) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3389) [M::mem_pestat] mean and std.dev: (982.68, 554.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4386) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.202 CPU sec, 58.006 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036687, 68, 33) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (274, 327, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (64, 589) [M::mem_pestat] mean and std.dev: (299.44, 89.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 694) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.80) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (264, 2205, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7317) [M::mem_pestat] mean and std.dev: (1869.17, 1581.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9668) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (332, 884, 2328) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6320) [M::mem_pestat] mean and std.dev: (1116.10, 1099.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8316) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1236.752 CPU sec, 76.113 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035285, 58, 32) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (278, 342, 406) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (22, 662) [M::mem_pestat] mean and std.dev: (297.39, 99.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 790) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (246, 2580, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7326) [M::mem_pestat] mean and std.dev: (1640.92, 1172.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9686) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (396, 1092, 1726) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4386) [M::mem_pestat] mean and std.dev: (1153.84, 849.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5716) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.643 CPU sec, 54.776 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035241, 67, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (233, 308, 365) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629) [M::mem_pestat] mean and std.dev: (269.67, 110.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 761) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1436, 2597, 3705) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8243) [M::mem_pestat] mean and std.dev: (2491.67, 1959.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10512) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (370, 879, 1553) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3919) [M::mem_pestat] mean and std.dev: (994.47, 783.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5102) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.661 CPU sec, 67.143 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 1036057, 50, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (224, 300, 344) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 584) [M::mem_pestat] mean and std.dev: (270.43, 88.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 704) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1521, 2598, 2622) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4824) [M::mem_pestat] mean and std.dev: (2105.15, 1160.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6749) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (279, 965, 1772) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4758) [M::mem_pestat] mean and std.dev: (1090.76, 937.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6251) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1216.120 CPU sec, 53.637 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1035139, 69, 30) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (271, 326, 383) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (47, 607) [M::mem_pestat] mean and std.dev: (295.57, 92.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 719) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1087, 2585, 2812) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6262) [M::mem_pestat] mean and std.dev: (1743.86, 1127.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7987) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (374, 1038, 1892) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4928) [M::mem_pestat] mean and std.dev: (1108.39, 993.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6446) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1224.957 CPU sec, 66.122 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1035507, 52, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (285, 333, 579) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1167) [M::mem_pestat] mean and std.dev: (358.92, 225.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1461) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1159, 2594, 2884) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6334) [M::mem_pestat] mean and std.dev: (1943.51, 1286.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8059) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (396, 951, 1295) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3093) [M::mem_pestat] mean and std.dev: (862.67, 580.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3992) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.076 CPU sec, 53.748 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 1036465, 72, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (273, 347, 396) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (27, 642) [M::mem_pestat] mean and std.dev: (291.47, 103.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 765) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (595, 2499, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6655) [M::mem_pestat] mean and std.dev: (1773.40, 1142.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8675) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (398, 1550, 2469) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6611) [M::mem_pestat] mean and std.dev: (1353.20, 957.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8682) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1264.764 CPU sec, 75.587 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036026, 69, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (271, 331, 399) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (15, 655) [M::mem_pestat] mean and std.dev: (291.53, 97.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 783) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (207, 2525, 3508) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10110) [M::mem_pestat] mean and std.dev: (2482.84, 2616.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13411) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (405, 787, 2398) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6384) [M::mem_pestat] mean and std.dev: (1192.95, 1261.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8377) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.095 CPU sec, 56.267 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1036458, 60, 11) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (288, 340, 562) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1110) [M::mem_pestat] mean and std.dev: (334.77, 235.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1384) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (437, 2288, 2897) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7817) [M::mem_pestat] mean and std.dev: (1531.06, 1212.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10277) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (355, 366, 1062) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2476) [M::mem_pestat] mean and std.dev: (748.18, 681.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3475) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1225.734 CPU sec, 61.193 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1036364, 54, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (305, 356, 1009) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2417) [M::mem_pestat] mean and std.dev: (524.04, 448.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3121) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (830, 2590, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6188) [M::mem_pestat] mean and std.dev: (1997.72, 1259.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7974) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (310, 717, 1117) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2731) [M::mem_pestat] mean and std.dev: (742.05, 503.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3538) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1200.477 CPU sec, 52.837 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036302, 67, 35) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (203, 314, 377) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725) [M::mem_pestat] mean and std.dev: (270.06, 113.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 899) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (704, 2600, 3246) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8330) [M::mem_pestat] mean and std.dev: (2343.13, 2035.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10872) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (476, 1041, 2024) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5120) [M::mem_pestat] mean and std.dev: (1356.82, 1078.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6668) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1214.990 CPU sec, 65.928 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035824, 70, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 351, 716) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1628) [M::mem_pestat] mean and std.dev: (365.33, 302.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2084) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (193, 2450, 2894) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8296) [M::mem_pestat] mean and std.dev: (1807.02, 1532.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10997) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (602, 1276, 1968) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4700) [M::mem_pestat] mean and std.dev: (1315.53, 899.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6066) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.478 CPU sec, 53.182 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036274, 62, 10) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (273, 332, 385) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (49, 609) [M::mem_pestat] mean and std.dev: (307.75, 87.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 721) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (174, 1900, 2618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7506) [M::mem_pestat] mean and std.dev: (1730.52, 1637.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9950) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (362, 1201, 1465) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3671) [M::mem_pestat] mean and std.dev: (1114.30, 790.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4774) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.444 CPU sec, 56.307 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1035668, 58, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (236, 318, 368) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 632) [M::mem_pestat] mean and std.dev: (254.67, 112.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 764) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1051, 2473, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5728) [M::mem_pestat] mean and std.dev: (1766.78, 1170.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7287) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (429, 960, 1269) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2949) [M::mem_pestat] mean and std.dev: (980.15, 649.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3789) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1250.448 CPU sec, 76.864 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 1035570, 57, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (274, 325, 389) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (44, 619) [M::mem_pestat] mean and std.dev: (304.98, 89.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 734) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (783, 2031, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6264) [M::mem_pestat] mean and std.dev: (1751.85, 1114.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8091) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (359, 1064, 1349) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3329) [M::mem_pestat] mean and std.dev: (995.57, 717.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4319) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.803 CPU sec, 55.164 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036288, 70, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (297, 335, 387) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (117, 567) [M::mem_pestat] mean and std.dev: (327.96, 58.61) [M::mem_pestat] low and high boundaries for proper pairs: (27, 657) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1891, 2599, 3581) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6961) [M::mem_pestat] mean and std.dev: (2110.30, 1307.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8651) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (425, 1204, 2018) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5204) [M::mem_pestat] mean and std.dev: (1263.21, 892.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6797) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.234 CPU sec, 67.062 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036613, 63, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (268, 320, 396) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (12, 652) [M::mem_pestat] mean and std.dev: (306.84, 113.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 780) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (202, 2582, 2604) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7408) [M::mem_pestat] mean and std.dev: (1473.95, 1208.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9810) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (411, 594, 1564) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3870) [M::mem_pestat] mean and std.dev: (1029.48, 881.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5023) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1205.749 CPU sec, 53.316 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036125, 56, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (244, 340, 408) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736) [M::mem_pestat] mean and std.dev: (286.98, 119.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 900) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (774, 2587, 2941) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7275) [M::mem_pestat] mean and std.dev: (1910.58, 1318.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9442) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (379, 447, 1097) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2533) [M::mem_pestat] mean and std.dev: (767.73, 557.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3251) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.679 CPU sec, 65.192 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036154, 80, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 331, 715) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1595) [M::mem_pestat] mean and std.dev: (446.26, 364.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2035) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (415, 2591, 2643) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7099) [M::mem_pestat] mean and std.dev: (1734.34, 1333.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9327) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (311, 794, 1521) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3941) [M::mem_pestat] mean and std.dev: (812.91, 684.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5151) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1204.584 CPU sec, 53.012 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035779, 70, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (280, 340, 528) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1024) [M::mem_pestat] mean and std.dev: (334.57, 160.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1272) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (314, 2564, 2623) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7241) [M::mem_pestat] mean and std.dev: (1823.25, 1451.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9550) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (343, 640, 1466) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3712) [M::mem_pestat] mean and std.dev: (960.86, 813.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4835) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1262.636 CPU sec, 75.287 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 1036760, 63, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (294, 354, 751) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1665) [M::mem_pestat] mean and std.dev: (418.72, 250.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2122) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (216, 2580, 2634) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7470) [M::mem_pestat] mean and std.dev: (1805.61, 1504.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9888) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (382, 886, 1774) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4558) [M::mem_pestat] mean and std.dev: (1075.44, 792.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5950) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.837 CPU sec, 55.892 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035833, 53, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (239, 327, 426) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 800) [M::mem_pestat] mean and std.dev: (252.29, 120.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 987) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (503, 1955, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6830) [M::mem_pestat] mean and std.dev: (1637.02, 1242.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8939) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (414, 1147, 1424) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3444) [M::mem_pestat] mean and std.dev: (950.70, 707.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4454) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1216.675 CPU sec, 67.487 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 1036504, 50, 30) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (210, 322, 702) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1686) [M::mem_pestat] mean and std.dev: (406.43, 322.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2178) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1251, 2593, 2964) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6390) [M::mem_pestat] mean and std.dev: (1905.60, 1268.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8103) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (419, 890, 1930) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4952) [M::mem_pestat] mean and std.dev: (1250.83, 1054.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6463) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1203.993 CPU sec, 53.186 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 1036185, 65, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (287, 340, 1201) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3029) [M::mem_pestat] mean and std.dev: (670.31, 669.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3943) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (939, 1958, 2608) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5946) [M::mem_pestat] mean and std.dev: (1828.89, 1089.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7615) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (480, 880, 2250) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5790) [M::mem_pestat] mean and std.dev: (1407.78, 1265.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7560) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.091 CPU sec, 65.407 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1035935, 62, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 320, 361) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (58, 563) [M::mem_pestat] mean and std.dev: (296.70, 76.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 664) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (591, 2599, 2924) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7590) [M::mem_pestat] mean and std.dev: (1949.16, 1259.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9923) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (341, 877, 1482) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3764) [M::mem_pestat] mean and std.dev: (1071.00, 925.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4905) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1200.832 CPU sec, 52.881 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1035714, 53, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 312, 368) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (65, 570) [M::mem_pestat] mean and std.dev: (289.77, 78.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 671) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (263, 1915, 2619) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7331) [M::mem_pestat] mean and std.dev: (1646.12, 1254.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9687) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (800, 1254, 1416) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648) [M::mem_pestat] mean and std.dev: (1050.22, 617.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3522) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1196.253 CPU sec, 54.457 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036515, 72, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (244, 327, 350) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (32, 562) [M::mem_pestat] mean and std.dev: (271.36, 100.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 672) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1230, 2595, 2958) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6414) [M::mem_pestat] mean and std.dev: (2102.85, 1347.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8142) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (426, 1055, 1642) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4074) [M::mem_pestat] mean and std.dev: (992.96, 650.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5290) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1256.744 CPU sec, 75.594 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1035745, 58, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (243, 314, 351) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (27, 567) [M::mem_pestat] mean and std.dev: (287.02, 97.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 679) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (357, 2579, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7122) [M::mem_pestat] mean and std.dev: (1679.91, 1132.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9377) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (382, 769, 1258) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3010) [M::mem_pestat] mean and std.dev: (912.30, 680.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3886) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1222.378 CPU sec, 56.028 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1036037, 67, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (269, 335, 389) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (29, 629) [M::mem_pestat] mean and std.dev: (298.05, 87.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 749) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (343, 2589, 3755) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10579) [M::mem_pestat] mean and std.dev: (3053.52, 2959.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14893) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (345, 852, 1827) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4791) [M::mem_pestat] mean and std.dev: (1125.14, 1050.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6273) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.238 CPU sec, 65.568 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1034946, 71, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (298, 354, 626) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1282) [M::mem_pestat] mean and std.dev: (372.41, 216.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1610) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (921, 2598, 2631) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6051) [M::mem_pestat] mean and std.dev: (1859.70, 1119.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7761) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (350, 915, 1693) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4379) [M::mem_pestat] mean and std.dev: (1048.48, 917.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5722) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.131 CPU sec, 53.415 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1035932, 53, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (240, 324, 372) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 636) [M::mem_pestat] mean and std.dev: (282.20, 100.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 768) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1440, 2589, 3386) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7278) [M::mem_pestat] mean and std.dev: (2193.00, 1483.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9224) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (376, 532, 1113) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2587) [M::mem_pestat] mean and std.dev: (638.00, 441.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3324) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.857 CPU sec, 67.431 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036197, 66, 12) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (241, 324, 381) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661) [M::mem_pestat] mean and std.dev: (266.07, 115.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 801) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (268, 2476, 3641) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10387) [M::mem_pestat] mean and std.dev: (2670.98, 2816.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13937) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (697, 1430, 3321) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8569) [M::mem_pestat] mean and std.dev: (1654.36, 1335.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11193) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.479 CPU sec, 53.265 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1036205, 57, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (252, 326, 374) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (8, 618) [M::mem_pestat] mean and std.dev: (273.00, 114.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 740) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (347, 2584, 2938) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8120) [M::mem_pestat] mean and std.dev: (2134.80, 1878.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10711) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (345, 442, 1212) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2946) [M::mem_pestat] mean and std.dev: (695.36, 560.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3813) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1249.092 CPU sec, 74.375 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035809, 61, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (254, 362, 1126) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2870) [M::mem_pestat] mean and std.dev: (575.48, 528.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3742) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (283, 2579, 2937) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8245) [M::mem_pestat] mean and std.dev: (1876.98, 1649.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10899) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (331, 670, 1730) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4528) [M::mem_pestat] mean and std.dev: (965.55, 876.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5927) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.151 CPU sec, 55.272 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 1036601, 69, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (293, 330, 609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1241) [M::mem_pestat] mean and std.dev: (380.40, 236.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1557) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (576, 2488, 2608) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6672) [M::mem_pestat] mean and std.dev: (1919.00, 1386.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8704) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (339, 976, 1831) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4815) [M::mem_pestat] mean and std.dev: (1143.21, 1164.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6307) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.672 CPU sec, 66.272 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1036719, 61, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 311, 807) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1887) [M::mem_pestat] mean and std.dev: (384.64, 334.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2427) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (724, 2588, 2893) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7231) [M::mem_pestat] mean and std.dev: (2013.88, 1468.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9400) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (316, 856, 1543) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3997) [M::mem_pestat] mean and std.dev: (866.76, 687.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5224) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.157 CPU sec, 53.265 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036391, 63, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (297, 329, 425) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (41, 681) [M::mem_pestat] mean and std.dev: (282.63, 114.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 809) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (216, 2581, 2766) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7866) [M::mem_pestat] mean and std.dev: (1997.43, 1900.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10416) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (343, 1140, 1831) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4807) [M::mem_pestat] mean and std.dev: (1210.00, 987.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6295) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.141 CPU sec, 65.656 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 1035875, 55, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (227, 304, 380) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 686) [M::mem_pestat] mean and std.dev: (259.00, 106.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 839) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (418, 2594, 2897) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7855) [M::mem_pestat] mean and std.dev: (2076.53, 1487.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10334) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (928, 1557, 2271) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4957) [M::mem_pestat] mean and std.dev: (1476.54, 669.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6300) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1204.172 CPU sec, 53.054 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1036472, 52, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (242, 329, 362) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (2, 602) [M::mem_pestat] mean and std.dev: (282.41, 126.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 790) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (248, 1885, 2915) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8249) [M::mem_pestat] mean and std.dev: (1737.91, 1747.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10916) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (404, 659, 1611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4025) [M::mem_pestat] mean and std.dev: (890.31, 676.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5232) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1197.931 CPU sec, 53.801 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1036057, 61, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (304, 332, 421) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (70, 655) [M::mem_pestat] mean and std.dev: (323.36, 51.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 772) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (429, 2567, 2618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6996) [M::mem_pestat] mean and std.dev: (1538.28, 1169.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9185) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (413, 763, 1289) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3041) [M::mem_pestat] mean and std.dev: (815.47, 509.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3917) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1263.049 CPU sec, 75.818 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 1035192, 53, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (210, 313, 588) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1344) [M::mem_pestat] mean and std.dev: (377.73, 320.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1722) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (256, 2589, 3492) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9964) [M::mem_pestat] mean and std.dev: (2544.21, 2493.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13200) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (388, 706, 1313) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3163) [M::mem_pestat] mean and std.dev: (722.57, 509.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4088) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1217.786 CPU sec, 55.950 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 1036774, 63, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (284, 322, 416) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (20, 680) [M::mem_pestat] mean and std.dev: (304.06, 94.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 812) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (254, 1916, 2820) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7952) [M::mem_pestat] mean and std.dev: (1697.98, 1499.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10518) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (377, 412, 1268) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3050) [M::mem_pestat] mean and std.dev: (713.76, 674.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3941) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.044 CPU sec, 67.703 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1036205, 63, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (284, 327, 492) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 908) [M::mem_pestat] mean and std.dev: (289.59, 155.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1116) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (307, 2540, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7222) [M::mem_pestat] mean and std.dev: (1771.29, 1371.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9527) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (340, 445, 1430) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3610) [M::mem_pestat] mean and std.dev: (799.71, 627.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4700) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1204.885 CPU sec, 53.325 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036302, 52, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (265, 310, 373) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (49, 589) [M::mem_pestat] mean and std.dev: (295.31, 91.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 697) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (271, 2495, 3479) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9895) [M::mem_pestat] mean and std.dev: (2523.06, 2536.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13103) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (884, 1187, 1849) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3779) [M::mem_pestat] mean and std.dev: (1247.16, 760.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4744) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.874 CPU sec, 66.946 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035747, 55, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 317, 375) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (42, 597) [M::mem_pestat] mean and std.dev: (292.00, 91.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 708) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (984, 2588, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5877) [M::mem_pestat] mean and std.dev: (1971.69, 1199.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7508) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (328, 1154, 2041) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5467) [M::mem_pestat] mean and std.dev: (1164.78, 1011.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7180) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1204.489 CPU sec, 53.012 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1036058, 57, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (296, 343, 435) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (18, 713) [M::mem_pestat] mean and std.dev: (299.14, 100.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 852) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (383, 2588, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7070) [M::mem_pestat] mean and std.dev: (1878.28, 1356.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9299) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (607, 982, 1908) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4510) [M::mem_pestat] mean and std.dev: (1066.41, 786.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5811) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1256.916 CPU sec, 74.875 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035377, 58, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (277, 326, 459) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 823) [M::mem_pestat] mean and std.dev: (303.48, 111.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1005) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1031, 2594, 2620) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5798) [M::mem_pestat] mean and std.dev: (1860.55, 1148.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7387) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (303, 609, 1191) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2967) [M::mem_pestat] mean and std.dev: (638.17, 424.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3855) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.312 CPU sec, 55.652 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1036569, 59, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 346, 389) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (14, 639) [M::mem_pestat] mean and std.dev: (280.47, 104.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 764) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (279, 2035, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7260) [M::mem_pestat] mean and std.dev: (1688.67, 1566.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9587) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (539, 1017, 2062) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5108) [M::mem_pestat] mean and std.dev: (1323.00, 859.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6631) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1212.375 CPU sec, 66.345 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035115, 62, 12) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 308, 372) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (48, 588) [M::mem_pestat] mean and std.dev: (281.67, 76.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 696) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (288, 2598, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7275) [M::mem_pestat] mean and std.dev: (1678.96, 1352.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9604) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (460, 1040, 1838) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4594) [M::mem_pestat] mean and std.dev: (1056.82, 642.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5972) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.031 CPU sec, 53.201 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1036734, 62, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (263, 316, 358) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (73, 548) [M::mem_pestat] mean and std.dev: (298.29, 80.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 643) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (243, 2580, 2608) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7338) [M::mem_pestat] mean and std.dev: (1724.47, 1381.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9703) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (270, 405, 607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1281) [M::mem_pestat] mean and std.dev: (341.90, 130.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1618) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.938 CPU sec, 66.172 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1036475, 63, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (240, 330, 383) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669) [M::mem_pestat] mean and std.dev: (282.15, 121.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 812) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (190, 2590, 2863) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8209) [M::mem_pestat] mean and std.dev: (2121.00, 1979.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10882) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (430, 1123, 1466) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3538) [M::mem_pestat] mean and std.dev: (1144.11, 811.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4574) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.162 CPU sec, 53.608 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1036511, 56, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (297, 331, 778) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1740) [M::mem_pestat] mean and std.dev: (460.60, 361.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2221) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (113, 1645, 2602) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7580) [M::mem_pestat] mean and std.dev: (1386.42, 1348.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10069) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (381, 1119, 1464) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3630) [M::mem_pestat] mean and std.dev: (1021.94, 737.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4713) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.152 CPU sec, 53.378 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035157, 74, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (221, 325, 405) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 773) [M::mem_pestat] mean and std.dev: (283.15, 138.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 957) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (187, 1755, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7456) [M::mem_pestat] mean and std.dev: (1620.58, 1575.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9879) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (345, 370, 1612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4146) [M::mem_pestat] mean and std.dev: (873.74, 884.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5413) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1253.742 CPU sec, 75.139 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035919, 66, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (238, 326, 448) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 868) [M::mem_pestat] mean and std.dev: (273.88, 148.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1078) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (323, 2327, 2958) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8228) [M::mem_pestat] mean and std.dev: (1968.00, 1742.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10863) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (280, 728, 1047) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2581) [M::mem_pestat] mean and std.dev: (714.89, 474.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3348) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1228.837 CPU sec, 56.248 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 1035793, 62, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (287, 341, 411) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (39, 659) [M::mem_pestat] mean and std.dev: (308.74, 100.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 783) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (574, 2606, 3401) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9055) [M::mem_pestat] mean and std.dev: (2444.81, 1946.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11882) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (436, 1015, 1195) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2713) [M::mem_pestat] mean and std.dev: (900.25, 516.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3472) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1223.205 CPU sec, 66.245 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 1036224, 65, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (263, 338, 475) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 899) [M::mem_pestat] mean and std.dev: (289.73, 109.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1111) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (420, 2591, 2624) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7032) [M::mem_pestat] mean and std.dev: (1845.45, 1298.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9236) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (354, 1007, 1665) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4287) [M::mem_pestat] mean and std.dev: (919.71, 598.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5598) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.306 CPU sec, 53.925 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035729, 52, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (279, 323, 400) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (37, 642) [M::mem_pestat] mean and std.dev: (299.91, 106.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 763) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1228, 2593, 2960) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6424) [M::mem_pestat] mean and std.dev: (2064.08, 1292.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8156) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (350, 819, 1676) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4328) [M::mem_pestat] mean and std.dev: (1005.10, 761.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5654) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1222.898 CPU sec, 67.199 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035713, 79, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 328, 758) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1754) [M::mem_pestat] mean and std.dev: (491.26, 434.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2252) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1155, 2597, 2970) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6600) [M::mem_pestat] mean and std.dev: (2057.71, 1337.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8415) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (405, 942, 1830) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4680) [M::mem_pestat] mean and std.dev: (1242.92, 1066.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6105) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.375 CPU sec, 53.384 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (36, 1036280, 76, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (295, 354, 721) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1573) [M::mem_pestat] mean and std.dev: (381.67, 254.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1999) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (199, 2320, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7453) [M::mem_pestat] mean and std.dev: (1810.61, 1575.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9871) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (411, 499, 1725) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4353) [M::mem_pestat] mean and std.dev: (839.00, 770.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5667) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1255.600 CPU sec, 75.011 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1036918, 55, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (288, 340, 383) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (98, 573) [M::mem_pestat] mean and std.dev: (326.73, 42.33) [M::mem_pestat] low and high boundaries for proper pairs: (3, 668) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (708, 2597, 3223) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8253) [M::mem_pestat] mean and std.dev: (1970.94, 1389.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10768) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (355, 655, 1287) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3151) [M::mem_pestat] mean and std.dev: (758.90, 507.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4083) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1224.121 CPU sec, 56.012 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 1036625, 47, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (269, 329, 980) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2402) [M::mem_pestat] mean and std.dev: (523.09, 447.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3113) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (404, 1924, 2608) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7016) [M::mem_pestat] mean and std.dev: (1741.20, 1315.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9220) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (318, 396, 1636) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4272) [M::mem_pestat] mean and std.dev: (999.19, 1187.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5749) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1212.942 CPU sec, 66.634 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036563, 66, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 334, 491) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 939) [M::mem_pestat] mean and std.dev: (288.19, 130.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1163) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (253, 2590, 2620) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7354) [M::mem_pestat] mean and std.dev: (1753.98, 1373.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9721) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (376, 874, 1713) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4387) [M::mem_pestat] mean and std.dev: (1031.45, 830.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5724) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.657 CPU sec, 53.439 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036267, 56, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (277, 334, 368) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (95, 550) [M::mem_pestat] mean and std.dev: (313.95, 74.57) [M::mem_pestat] low and high boundaries for proper pairs: (4, 641) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (409, 2595, 3829) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10669) [M::mem_pestat] mean and std.dev: (2866.38, 2633.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14089) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (402, 781, 1663) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4185) [M::mem_pestat] mean and std.dev: (1055.96, 845.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5446) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.195 CPU sec, 64.718 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 1035824, 66, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (278, 316, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (76, 581) [M::mem_pestat] mean and std.dev: (302.88, 71.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 682) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (416, 2324, 2635) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7073) [M::mem_pestat] mean and std.dev: (1716.87, 1204.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9292) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (684, 913, 2229) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5319) [M::mem_pestat] mean and std.dev: (1402.21, 1301.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6864) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.616 CPU sec, 53.407 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035130, 62, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (204, 297, 361) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675) [M::mem_pestat] mean and std.dev: (253.83, 122.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 832) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (628, 2580, 2985) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7699) [M::mem_pestat] mean and std.dev: (2028.49, 1404.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10056) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (414, 1268, 1903) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4881) [M::mem_pestat] mean and std.dev: (1095.00, 760.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6370) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1201.218 CPU sec, 52.862 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036030, 71, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (272, 340, 399) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (18, 653) [M::mem_pestat] mean and std.dev: (288.86, 99.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 780) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (273, 2587, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7287) [M::mem_pestat] mean and std.dev: (1803.26, 1293.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9625) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (1052, 1553, 3051) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7049) [M::mem_pestat] mean and std.dev: (1887.81, 1628.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9048) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1270.969 CPU sec, 75.169 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1035939, 63, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (261, 325, 399) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 675) [M::mem_pestat] mean and std.dev: (282.89, 120.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 813) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1033, 2589, 3219) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7591) [M::mem_pestat] mean and std.dev: (2040.56, 1681.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9777) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (463, 1055, 2466) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6472) [M::mem_pestat] mean and std.dev: (1598.63, 1628.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8475) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.539 CPU sec, 55.395 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036202, 49, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (282, 332, 793) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1815) [M::mem_pestat] mean and std.dev: (500.89, 437.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2326) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (204, 2557, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7443) [M::mem_pestat] mean and std.dev: (1642.91, 1295.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9856) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (304, 782, 1931) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5185) [M::mem_pestat] mean and std.dev: (1157.76, 1298.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6812) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1223.071 CPU sec, 67.663 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035890, 54, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (249, 318, 372) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (3, 618) [M::mem_pestat] mean and std.dev: (278.18, 86.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 741) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (340, 2356, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7159) [M::mem_pestat] mean and std.dev: (1718.60, 1419.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9432) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (349, 1081, 2687) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7363) [M::mem_pestat] mean and std.dev: (1535.64, 1674.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9701) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.131 CPU sec, 53.926 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1037281, 59, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (257, 315, 376) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (19, 614) [M::mem_pestat] mean and std.dev: (288.15, 98.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 733) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.41, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (393, 2297, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7053) [M::mem_pestat] mean and std.dev: (1738.13, 1401.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9273) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (320, 570, 1628) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4244) [M::mem_pestat] mean and std.dev: (907.83, 856.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5552) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1217.448 CPU sec, 66.729 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035427, 56, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (248, 335, 892) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2180) [M::mem_pestat] mean and std.dev: (435.61, 347.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2824) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (385, 2566, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7081) [M::mem_pestat] mean and std.dev: (1766.38, 1309.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9313) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (393, 918, 1389) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3381) [M::mem_pestat] mean and std.dev: (873.91, 672.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4377) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.105 CPU sec, 53.401 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035992, 73, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (263, 333, 436) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782) [M::mem_pestat] mean and std.dev: (302.71, 132.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 955) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (284, 2588, 2975) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8357) [M::mem_pestat] mean and std.dev: (2130.27, 1773.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11048) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (463, 1470, 1890) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4744) [M::mem_pestat] mean and std.dev: (1380.36, 955.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6171) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1272.878 CPU sec, 76.037 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 1036250, 55, 29) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (272, 322, 385) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (46, 611) [M::mem_pestat] mean and std.dev: (287.34, 95.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 724) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (524, 2585, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6779) [M::mem_pestat] mean and std.dev: (1988.54, 1317.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8864) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (411, 852, 1316) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3126) [M::mem_pestat] mean and std.dev: (882.82, 507.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4031) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.669 CPU sec, 55.672 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036717, 69, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (299, 344, 585) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1157) [M::mem_pestat] mean and std.dev: (356.42, 214.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1443) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1357, 2600, 2899) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5983) [M::mem_pestat] mean and std.dev: (2023.85, 1349.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7525) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (532, 1181, 1781) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4279) [M::mem_pestat] mean and std.dev: (1054.57, 599.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5528) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.571 CPU sec, 66.168 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036782, 50, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (294, 347, 711) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1545) [M::mem_pestat] mean and std.dev: (397.79, 299.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1962) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.41, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (157, 2582, 2620) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7546) [M::mem_pestat] mean and std.dev: (1802.59, 1548.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10009) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (421, 925, 1143) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2587) [M::mem_pestat] mean and std.dev: (861.41, 568.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3309) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1197.930 CPU sec, 52.987 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035561, 54, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 339, 555) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1115) [M::mem_pestat] mean and std.dev: (359.40, 218.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1395) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (299, 2492, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7229) [M::mem_pestat] mean and std.dev: (1610.51, 1377.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9539) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (347, 736, 1420) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3566) [M::mem_pestat] mean and std.dev: (778.00, 525.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4639) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.375 CPU sec, 69.143 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1036556, 60, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (270, 337, 540) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1080) [M::mem_pestat] mean and std.dev: (316.65, 170.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1350) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (768, 2595, 2914) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7206) [M::mem_pestat] mean and std.dev: (2155.75, 1464.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9352) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (368, 888, 1424) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3536) [M::mem_pestat] mean and std.dev: (977.68, 724.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4592) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1197.680 CPU sec, 52.757 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1035149, 59, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (241, 305, 364) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 610) [M::mem_pestat] mean and std.dev: (274.58, 109.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 733) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (311, 2092, 2622) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7244) [M::mem_pestat] mean and std.dev: (1601.74, 1382.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9555) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (435, 490, 1418) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3384) [M::mem_pestat] mean and std.dev: (873.94, 554.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4367) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1197.875 CPU sec, 52.782 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1036613, 51, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (283, 327, 419) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (11, 691) [M::mem_pestat] mean and std.dev: (283.82, 103.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 827) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (237, 2050, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7371) [M::mem_pestat] mean and std.dev: (1645.85, 1494.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9749) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (285, 1029, 2449) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6777) [M::mem_pestat] mean and std.dev: (1311.45, 1450.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8941) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1248.572 CPU sec, 74.920 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1034751, 72, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (278, 319, 403) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (28, 653) [M::mem_pestat] mean and std.dev: (287.40, 98.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 778) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (293, 2577, 3478) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9848) [M::mem_pestat] mean and std.dev: (2650.00, 2610.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13094) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (386, 962, 2003) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5237) [M::mem_pestat] mean and std.dev: (1064.32, 917.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6854) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.309 CPU sec, 56.050 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1036053, 69, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (268, 315, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (46, 601) [M::mem_pestat] mean and std.dev: (293.78, 96.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 712) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.41, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (476, 2162, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6875) [M::mem_pestat] mean and std.dev: (1736.22, 1193.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9008) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (409, 1188, 2181) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5725) [M::mem_pestat] mean and std.dev: (1172.50, 861.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7497) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.775 CPU sec, 65.097 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1035601, 57, 33) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 328, 385) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (10, 635) [M::mem_pestat] mean and std.dev: (290.63, 99.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 760) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (336, 1936, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7155) [M::mem_pestat] mean and std.dev: (1646.52, 1294.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9428) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (343, 1133, 2749) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7561) [M::mem_pestat] mean and std.dev: (1490.21, 1295.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9967) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.714 CPU sec, 53.430 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036146, 68, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (194, 301, 390) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 782) [M::mem_pestat] mean and std.dev: (253.77, 112.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 978) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1646, 2596, 2967) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5609) [M::mem_pestat] mean and std.dev: (2194.47, 1223.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7089) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (429, 1179, 1929) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4929) [M::mem_pestat] mean and std.dev: (1312.78, 1033.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6429) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.887 CPU sec, 65.076 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1036148, 68, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (257, 344, 850) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2036) [M::mem_pestat] mean and std.dev: (487.53, 426.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2629) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (420, 2583, 2782) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7506) [M::mem_pestat] mean and std.dev: (1933.84, 1672.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9868) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (288, 926, 1755) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4689) [M::mem_pestat] mean and std.dev: (994.42, 938.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6156) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.181 CPU sec, 53.193 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1035678, 75, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (226, 308, 415) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 793) [M::mem_pestat] mean and std.dev: (272.24, 127.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 982) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (342, 1953, 2635) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7221) [M::mem_pestat] mean and std.dev: (1726.04, 1499.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9514) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (497, 867, 1815) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4451) [M::mem_pestat] mean and std.dev: (1339.77, 1212.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6188) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1269.715 CPU sec, 75.671 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 1036659, 52, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (283, 338, 600) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1234) [M::mem_pestat] mean and std.dev: (357.40, 193.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1551) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (142, 1892, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7558) [M::mem_pestat] mean and std.dev: (1682.06, 1426.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10030) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (372, 949, 1711) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4389) [M::mem_pestat] mean and std.dev: (964.50, 776.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5728) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.814 CPU sec, 55.775 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035781, 68, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (295, 328, 362) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (161, 496) [M::mem_pestat] mean and std.dev: (314.68, 54.37) [M::mem_pestat] low and high boundaries for proper pairs: (94, 563) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (432, 2582, 2620) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6996) [M::mem_pestat] mean and std.dev: (1917.13, 1390.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9184) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (290, 445, 1426) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3698) [M::mem_pestat] mean and std.dev: (659.05, 557.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4834) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1227.803 CPU sec, 68.904 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035634, 54, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (259, 314, 381) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (15, 625) [M::mem_pestat] mean and std.dev: (278.51, 95.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 747) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.41, 12.80) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (381, 2597, 2848) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7782) [M::mem_pestat] mean and std.dev: (1953.69, 1606.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10249) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (423, 1027, 1679) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4191) [M::mem_pestat] mean and std.dev: (1107.92, 912.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5447) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1202.819 CPU sec, 53.645 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1035382, 56, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (248, 322, 349) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (46, 551) [M::mem_pestat] mean and std.dev: (274.76, 92.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 652) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1192, 2514, 2631) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5509) [M::mem_pestat] mean and std.dev: (1782.55, 1089.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6948) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (420, 1047, 1899) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4857) [M::mem_pestat] mean and std.dev: (1156.00, 977.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6336) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.573 CPU sec, 65.880 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1035514, 57, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (193, 308, 361) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 697) [M::mem_pestat] mean and std.dev: (249.62, 122.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 865) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.41, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (573, 2590, 4171) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11367) [M::mem_pestat] mean and std.dev: (2674.37, 2407.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14965) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (371, 580, 1880) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4898) [M::mem_pestat] mean and std.dev: (1021.32, 854.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6407) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1205.025 CPU sec, 53.064 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035447, 67, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (308, 356, 588) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1148) [M::mem_pestat] mean and std.dev: (423.21, 243.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1428) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1156, 2597, 3628) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8572) [M::mem_pestat] mean and std.dev: (2867.67, 2670.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13550) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (386, 775, 1806) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4646) [M::mem_pestat] mean and std.dev: (1172.11, 1064.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6066) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1196.118 CPU sec, 52.725 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035823, 55, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (234, 307, 350) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (2, 582) [M::mem_pestat] mean and std.dev: (282.63, 82.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 698) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (134, 1629, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7550) [M::mem_pestat] mean and std.dev: (1460.11, 1181.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10022) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (369, 731, 1393) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3441) [M::mem_pestat] mean and std.dev: (1009.52, 816.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4465) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1225.038 CPU sec, 77.647 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 1036431, 57, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (262, 319, 414) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718) [M::mem_pestat] mean and std.dev: (283.70, 101.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 870) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (862, 2606, 3693) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9355) [M::mem_pestat] mean and std.dev: (2929.28, 2404.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12549) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (369, 736, 1409) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3489) [M::mem_pestat] mean and std.dev: (784.35, 572.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4529) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.031 CPU sec, 54.680 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 1036064, 45, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (265, 324, 398) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 664) [M::mem_pestat] mean and std.dev: (278.81, 107.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 797) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (153, 1894, 2954) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8556) [M::mem_pestat] mean and std.dev: (2075.43, 2094.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11357) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (379, 860, 1466) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3640) [M::mem_pestat] mean and std.dev: (963.82, 719.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4727) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.201 CPU sec, 67.950 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1036014, 58, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (276, 320, 391) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (46, 621) [M::mem_pestat] mean and std.dev: (299.93, 90.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 736) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (299, 2596, 3173) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8921) [M::mem_pestat] mean and std.dev: (2718.46, 2634.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13258) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (876, 1122, 1782) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3594) [M::mem_pestat] mean and std.dev: (1152.08, 571.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4500) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1203.069 CPU sec, 53.066 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1036687, 74, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (259, 326, 370) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (37, 592) [M::mem_pestat] mean and std.dev: (293.05, 82.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 703) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (288, 1919, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7266) [M::mem_pestat] mean and std.dev: (1800.49, 1605.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9592) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (727, 1321, 2593) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6325) [M::mem_pestat] mean and std.dev: (1597.17, 1252.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8191) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.066 CPU sec, 64.172 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036220, 52, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (241, 311, 838) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2032) [M::mem_pestat] mean and std.dev: (428.94, 379.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2629) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (812, 2599, 2940) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7196) [M::mem_pestat] mean and std.dev: (2128.76, 1536.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9324) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (332, 395, 857) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1907) [M::mem_pestat] mean and std.dev: (497.00, 341.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2432) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1202.085 CPU sec, 52.941 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035357, 49, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 307, 399) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 669) [M::mem_pestat] mean and std.dev: (282.00, 115.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 804) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1078, 2600, 5254) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 13606) [M::mem_pestat] mean and std.dev: (3288.24, 2823.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 17782) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (392, 857, 2233) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5915) [M::mem_pestat] mean and std.dev: (1281.56, 1085.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7756) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1265.795 CPU sec, 75.881 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035226, 60, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (215, 302, 361) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 653) [M::mem_pestat] mean and std.dev: (273.56, 101.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 799) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (825, 2591, 3236) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8058) [M::mem_pestat] mean and std.dev: (1976.53, 1547.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10469) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (346, 1057, 1563) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3997) [M::mem_pestat] mean and std.dev: (993.25, 719.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5214) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.655 CPU sec, 56.180 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035880, 68, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (234, 306, 403) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741) [M::mem_pestat] mean and std.dev: (256.05, 101.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 910) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (178, 1919, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7489) [M::mem_pestat] mean and std.dev: (1465.19, 1356.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9926) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (321, 493, 1585) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4113) [M::mem_pestat] mean and std.dev: (976.90, 847.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5377) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.178 CPU sec, 65.255 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036204, 59, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (258, 315, 369) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (36, 591) [M::mem_pestat] mean and std.dev: (297.19, 84.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 702) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (332, 2072, 2631) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7229) [M::mem_pestat] mean and std.dev: (1766.70, 1441.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9528) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (585, 1105, 1438) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3144) [M::mem_pestat] mean and std.dev: (1035.87, 691.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3997) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.239 CPU sec, 53.386 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035741, 50, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (253, 309, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631) [M::mem_pestat] mean and std.dev: (272.10, 106.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 757) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (303, 1926, 3624) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10266) [M::mem_pestat] mean and std.dev: (2692.82, 2742.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13664) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (398, 1030, 1285) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3059) [M::mem_pestat] mean and std.dev: (815.16, 434.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3946) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1225.764 CPU sec, 68.012 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1034880, 63, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (284, 333, 417) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (18, 683) [M::mem_pestat] mean and std.dev: (290.94, 105.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 816) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (512, 2596, 2848) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7520) [M::mem_pestat] mean and std.dev: (2107.27, 1501.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9856) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (417, 786, 1549) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3813) [M::mem_pestat] mean and std.dev: (929.38, 711.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4945) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.402 CPU sec, 53.904 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035095, 59, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (188, 322, 434) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 926) [M::mem_pestat] mean and std.dev: (280.86, 132.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1172) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1021, 2579, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5806) [M::mem_pestat] mean and std.dev: (1944.22, 1320.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7401) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (320, 1226, 1971) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5273) [M::mem_pestat] mean and std.dev: (1354.65, 1005.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6924) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1264.101 CPU sec, 75.509 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 1035449, 88, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (294, 326, 437) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (8, 723) [M::mem_pestat] mean and std.dev: (312.36, 98.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 866) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (468, 2588, 2842) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7590) [M::mem_pestat] mean and std.dev: (2085.92, 1779.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9964) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (378, 1007, 1658) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4218) [M::mem_pestat] mean and std.dev: (1074.94, 1032.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5498) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.011 CPU sec, 56.271 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1036522, 53, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 355, 809) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1893) [M::mem_pestat] mean and std.dev: (464.58, 353.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2435) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (728, 2515, 2851) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7097) [M::mem_pestat] mean and std.dev: (1743.02, 1204.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9220) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (394, 995, 1485) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3667) [M::mem_pestat] mean and std.dev: (1017.50, 773.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4758) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.839 CPU sec, 67.487 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035894, 78, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (283, 347, 964) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2326) [M::mem_pestat] mean and std.dev: (538.12, 494.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3007) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (285, 2576, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7281) [M::mem_pestat] mean and std.dev: (1746.44, 1401.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9613) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (383, 851, 1597) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4025) [M::mem_pestat] mean and std.dev: (906.85, 660.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5239) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1206.408 CPU sec, 53.336 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035113, 66, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (237, 318, 363) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 615) [M::mem_pestat] mean and std.dev: (272.00, 93.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 741) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (395, 2586, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7043) [M::mem_pestat] mean and std.dev: (1750.70, 1339.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9259) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (376, 1320, 2475) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6673) [M::mem_pestat] mean and std.dev: (1605.88, 1582.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8772) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1214.920 CPU sec, 67.940 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1036024, 60, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 318, 385) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (22, 627) [M::mem_pestat] mean and std.dev: (280.10, 95.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 748) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (296, 1793, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7256) [M::mem_pestat] mean and std.dev: (1604.30, 1367.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9576) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (346, 1101, 1656) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4276) [M::mem_pestat] mean and std.dev: (996.89, 714.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5586) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1204.991 CPU sec, 53.278 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 1036824, 64, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (228, 312, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681) [M::mem_pestat] mean and std.dev: (270.54, 124.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 832) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.80) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (815, 2532, 2905) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7085) [M::mem_pestat] mean and std.dev: (1890.88, 1299.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9175) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (432, 1147, 1583) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3885) [M::mem_pestat] mean and std.dev: (1085.92, 751.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5036) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1212.623 CPU sec, 64.206 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1035612, 63, 32) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (265, 338, 393) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (9, 649) [M::mem_pestat] mean and std.dev: (280.57, 94.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 777) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.80) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1466, 2606, 3911) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8801) [M::mem_pestat] mean and std.dev: (3339.62, 2746.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14325) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (372, 672, 1404) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468) [M::mem_pestat] mean and std.dev: (858.81, 650.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4500) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1242.070 CPU sec, 76.604 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1035525, 72, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (236, 332, 361) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 611) [M::mem_pestat] mean and std.dev: (267.75, 114.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 736) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1431, 2597, 2694) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5220) [M::mem_pestat] mean and std.dev: (1992.50, 1181.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6719) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (380, 871, 1744) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4472) [M::mem_pestat] mean and std.dev: (970.30, 762.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5836) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.030 CPU sec, 53.645 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035278, 69, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (224, 324, 414) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 794) [M::mem_pestat] mean and std.dev: (284.43, 114.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 984) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1411, 2561, 2824) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5650) [M::mem_pestat] mean and std.dev: (1947.70, 1145.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7063) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (315, 845, 1503) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3879) [M::mem_pestat] mean and std.dev: (972.00, 806.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5067) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.366 CPU sec, 64.754 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036275, 60, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (231, 324, 374) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 660) [M::mem_pestat] mean and std.dev: (280.02, 121.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 803) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1080, 2575, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5670) [M::mem_pestat] mean and std.dev: (1853.84, 1103.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7200) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (451, 936, 1487) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3559) [M::mem_pestat] mean and std.dev: (981.63, 491.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4595) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1200.403 CPU sec, 52.828 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035777, 55, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (235, 305, 391) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 703) [M::mem_pestat] mean and std.dev: (252.90, 108.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 859) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.80) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (241, 1904, 3654) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10480) [M::mem_pestat] mean and std.dev: (2842.51, 2993.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14817) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (375, 1261, 1638) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4164) [M::mem_pestat] mean and std.dev: (1247.84, 878.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5427) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.810 CPU sec, 63.217 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035566, 61, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (270, 321, 428) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 744) [M::mem_pestat] mean and std.dev: (281.78, 87.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 902) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (380, 1912, 2683) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7289) [M::mem_pestat] mean and std.dev: (1821.64, 1446.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9592) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (797, 1188, 1552) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3062) [M::mem_pestat] mean and std.dev: (1111.73, 546.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3817) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1197.676 CPU sec, 52.670 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1035467, 68, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (251, 336, 515) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1043) [M::mem_pestat] mean and std.dev: (314.06, 165.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1307) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (734, 2585, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6374) [M::mem_pestat] mean and std.dev: (1874.80, 1193.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8254) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (417, 955, 1443) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3495) [M::mem_pestat] mean and std.dev: (1051.74, 801.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4521) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1264.452 CPU sec, 75.382 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035665, 67, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (259, 316, 365) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (47, 577) [M::mem_pestat] mean and std.dev: (272.86, 86.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 683) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (478, 2587, 2627) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6925) [M::mem_pestat] mean and std.dev: (1881.79, 1429.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9074) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (349, 831, 1655) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4267) [M::mem_pestat] mean and std.dev: (894.50, 829.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5573) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.934 CPU sec, 55.691 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1035682, 52, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (253, 327, 436) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 802) [M::mem_pestat] mean and std.dev: (288.80, 147.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 985) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (215, 2052, 2604) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7382) [M::mem_pestat] mean and std.dev: (1563.77, 1253.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9771) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (851, 1172, 2198) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4892) [M::mem_pestat] mean and std.dev: (1278.80, 865.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6239) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.864 CPU sec, 66.020 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035770, 67, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (280, 327, 383) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (74, 589) [M::mem_pestat] mean and std.dev: (291.48, 88.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 692) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (365, 2571, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7115) [M::mem_pestat] mean and std.dev: (1736.71, 1296.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9365) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (362, 1916, 2566) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6974) [M::mem_pestat] mean and std.dev: (1809.53, 1662.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9178) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1198.009 CPU sec, 52.941 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1035048, 64, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (272, 342, 382) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (52, 602) [M::mem_pestat] mean and std.dev: (302.70, 103.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 716) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (435, 2137, 2628) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7014) [M::mem_pestat] mean and std.dev: (1812.12, 1390.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9207) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (699, 1071, 2268) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5406) [M::mem_pestat] mean and std.dev: (1249.26, 806.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6975) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.345 CPU sec, 69.269 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036760, 67, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (303, 339, 740) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1614) [M::mem_pestat] mean and std.dev: (364.71, 254.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2051) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (385, 2589, 2964) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8122) [M::mem_pestat] mean and std.dev: (1974.37, 1602.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10701) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (386, 607, 1475) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3653) [M::mem_pestat] mean and std.dev: (947.38, 768.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4742) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1201.164 CPU sec, 53.115 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 1036557, 58, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (248, 333, 466) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 902) [M::mem_pestat] mean and std.dev: (319.77, 179.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1120) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (305, 2586, 2641) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7313) [M::mem_pestat] mean and std.dev: (1815.67, 1418.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9649) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (442, 884, 1498) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3610) [M::mem_pestat] mean and std.dev: (892.11, 516.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4666) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.101 CPU sec, 63.473 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035946, 55, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (291, 337, 485) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 873) [M::mem_pestat] mean and std.dev: (333.70, 114.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1067) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (173, 2071, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7502) [M::mem_pestat] mean and std.dev: (1818.65, 1656.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9945) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (427, 1153, 1734) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4348) [M::mem_pestat] mean and std.dev: (1176.18, 848.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5655) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 2666668 sequences (240000120 bp)... [M::mem_process_seqs] Processed 2666668 reads in 1236.792 CPU sec, 76.339 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 1036262, 75, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (227, 320, 387) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 707) [M::mem_pestat] mean and std.dev: (273.93, 98.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 867) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (216, 2386, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7413) [M::mem_pestat] mean and std.dev: (1749.62, 1538.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9812) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (373, 912, 1362) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3340) [M::mem_pestat] mean and std.dev: (926.69, 689.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4329) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1205.200 CPU sec, 53.296 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1035316, 70, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 318, 411) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 713) [M::mem_pestat] mean and std.dev: (301.31, 127.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 864) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (389, 2576, 2946) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8060) [M::mem_pestat] mean and std.dev: (2020.48, 1713.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10617) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (400, 658, 1511) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3733) [M::mem_pestat] mean and std.dev: (879.48, 709.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4844) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1230.992 CPU sec, 68.694 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1035773, 74, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (290, 335, 416) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (38, 668) [M::mem_pestat] mean and std.dev: (304.22, 122.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 796) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (360, 2059, 2856) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7848) [M::mem_pestat] mean and std.dev: (1727.64, 1679.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10344) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (387, 828, 1391) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3399) [M::mem_pestat] mean and std.dev: (991.45, 726.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4403) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1214.767 CPU sec, 53.497 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036172, 66, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (253, 327, 857) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2065) [M::mem_pestat] mean and std.dev: (401.93, 351.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2669) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (207, 1875, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7416) [M::mem_pestat] mean and std.dev: (1440.55, 1403.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9819) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (267, 600, 1559) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4143) [M::mem_pestat] mean and std.dev: (692.09, 655.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5435) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.380 CPU sec, 65.023 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1035905, 53, 12) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (250, 333, 392) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 676) [M::mem_pestat] mean and std.dev: (283.15, 102.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 818) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (788, 2577, 2627) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6305) [M::mem_pestat] mean and std.dev: (1802.76, 1301.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8144) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (349, 422, 1681) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4345) [M::mem_pestat] mean and std.dev: (922.75, 818.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5677) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.885 CPU sec, 53.277 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1035392, 43, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (286, 321, 408) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (42, 652) [M::mem_pestat] mean and std.dev: (274.32, 98.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 774) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (339, 2579, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7152) [M::mem_pestat] mean and std.dev: (1836.50, 1448.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9423) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (416, 793, 1235) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2873) [M::mem_pestat] mean and std.dev: (780.48, 463.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3692) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1267.590 CPU sec, 74.860 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035381, 54, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (303, 336, 466) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 792) [M::mem_pestat] mean and std.dev: (322.80, 141.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 955) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (134, 1890, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7568) [M::mem_pestat] mean and std.dev: (1598.31, 1576.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10046) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (357, 1193, 1464) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3678) [M::mem_pestat] mean and std.dev: (1096.05, 866.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4785) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1222.123 CPU sec, 55.668 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1035799, 57, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (288, 340, 405) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (54, 639) [M::mem_pestat] mean and std.dev: (312.82, 84.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 756) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (330, 2491, 2934) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8142) [M::mem_pestat] mean and std.dev: (1891.43, 1587.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10746) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (313, 886, 3604) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10186) [M::mem_pestat] mean and std.dev: (2118.13, 2314.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13477) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.848 CPU sec, 68.243 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035508, 72, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (197, 302, 415) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 851) [M::mem_pestat] mean and std.dev: (269.40, 137.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1069) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (310, 2511, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7207) [M::mem_pestat] mean and std.dev: (1695.33, 1400.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9506) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (305, 1046, 1579) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4127) [M::mem_pestat] mean and std.dev: (953.25, 654.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5401) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1197.976 CPU sec, 52.900 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 1036423, 53, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (295, 349, 781) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1753) [M::mem_pestat] mean and std.dev: (411.16, 309.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2239) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.41, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (540, 1801, 2608) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6744) [M::mem_pestat] mean and std.dev: (1749.69, 1514.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8812) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (377, 987, 2184) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5798) [M::mem_pestat] mean and std.dev: (1284.40, 1145.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7605) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.240 CPU sec, 66.149 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 1035992, 63, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (229, 326, 373) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 661) [M::mem_pestat] mean and std.dev: (277.00, 114.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 805) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (814, 2557, 2623) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6241) [M::mem_pestat] mean and std.dev: (1857.88, 1298.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8050) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (357, 967, 1603) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4095) [M::mem_pestat] mean and std.dev: (863.14, 572.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5341) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1204.252 CPU sec, 53.031 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036393, 62, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (257, 326, 374) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (23, 608) [M::mem_pestat] mean and std.dev: (284.69, 99.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 725) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (246, 1949, 2604) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7320) [M::mem_pestat] mean and std.dev: (1507.19, 1335.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9678) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (418, 848, 4055) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 11329) [M::mem_pestat] mean and std.dev: (2110.52, 2423.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14966) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1217.590 CPU sec, 63.264 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1035498, 58, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (268, 325, 986) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2422) [M::mem_pestat] mean and std.dev: (512.94, 417.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3140) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (390, 1609, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7071) [M::mem_pestat] mean and std.dev: (1651.54, 1440.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9298) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (895, 1364, 2371) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5323) [M::mem_pestat] mean and std.dev: (1222.38, 752.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6799) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1244.207 CPU sec, 77.414 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035710, 67, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (272, 317, 380) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (56, 596) [M::mem_pestat] mean and std.dev: (298.77, 84.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 704) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (222, 2021, 2852) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8112) [M::mem_pestat] mean and std.dev: (1722.18, 1537.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10742) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (406, 1050, 2164) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5680) [M::mem_pestat] mean and std.dev: (1507.17, 1453.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7438) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.879 CPU sec, 54.258 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035448, 62, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (257, 328, 390) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 656) [M::mem_pestat] mean and std.dev: (291.35, 87.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 789) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1415, 2600, 3401) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7373) [M::mem_pestat] mean and std.dev: (2100.60, 1517.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9359) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (386, 929, 2410) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6458) [M::mem_pestat] mean and std.dev: (1357.36, 1425.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8482) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1229.469 CPU sec, 66.379 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035864, 60, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (289, 338, 445) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 757) [M::mem_pestat] mean and std.dev: (321.76, 102.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 913) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (709, 2600, 3590) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9352) [M::mem_pestat] mean and std.dev: (2471.47, 1950.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12233) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (370, 798, 1137) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2671) [M::mem_pestat] mean and std.dev: (827.91, 607.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3438) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.392 CPU sec, 53.241 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 1035750, 72, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (253, 328, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631) [M::mem_pestat] mean and std.dev: (261.49, 119.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 757) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (481, 2587, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6871) [M::mem_pestat] mean and std.dev: (1920.76, 1300.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9001) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (350, 415, 1312) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3236) [M::mem_pestat] mean and std.dev: (587.70, 474.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4198) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1223.106 CPU sec, 67.753 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (70, 1035866, 72, 13) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (251, 321, 388) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 662) [M::mem_pestat] mean and std.dev: (285.11, 103.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 799) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (322, 2592, 3247) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9097) [M::mem_pestat] mean and std.dev: (2463.90, 2297.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12022) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (441, 1109, 3104) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8430) [M::mem_pestat] mean and std.dev: (1645.46, 1582.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11093) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1204.037 CPU sec, 53.111 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036675, 49, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (235, 304, 359) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 607) [M::mem_pestat] mean and std.dev: (252.95, 112.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 731) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1117, 2591, 2885) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6421) [M::mem_pestat] mean and std.dev: (1890.73, 1192.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8189) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (298, 629, 1787) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4765) [M::mem_pestat] mean and std.dev: (863.55, 717.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6254) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1267.503 CPU sec, 75.218 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036014, 53, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (291, 333, 409) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (55, 645) [M::mem_pestat] mean and std.dev: (303.69, 69.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 763) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (440, 2594, 2835) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7625) [M::mem_pestat] mean and std.dev: (2199.21, 1792.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10020) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (439, 852, 2146) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5560) [M::mem_pestat] mean and std.dev: (1042.86, 710.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7267) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.987 CPU sec, 55.425 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036411, 57, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (291, 334, 422) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (29, 684) [M::mem_pestat] mean and std.dev: (303.33, 102.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 815) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1035, 2585, 3822) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9396) [M::mem_pestat] mean and std.dev: (2776.62, 2540.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12938) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (491, 1278, 2414) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6260) [M::mem_pestat] mean and std.dev: (1624.39, 1521.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8183) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1193.298 CPU sec, 59.897 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036096, 45, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (252, 341, 386) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 654) [M::mem_pestat] mean and std.dev: (284.26, 121.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 788) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (301, 2590, 2962) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8284) [M::mem_pestat] mean and std.dev: (1919.24, 1779.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10945) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (705, 866, 1704) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3702) [M::mem_pestat] mean and std.dev: (865.56, 438.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4701) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.217 CPU sec, 53.435 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035923, 63, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (277, 316, 425) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721) [M::mem_pestat] mean and std.dev: (291.35, 126.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 869) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.41, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (290, 1690, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7253) [M::mem_pestat] mean and std.dev: (1477.14, 1322.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9574) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (444, 933, 1498) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3606) [M::mem_pestat] mean and std.dev: (922.73, 549.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4660) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1201.167 CPU sec, 59.518 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036312, 48, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (270, 332, 465) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 855) [M::mem_pestat] mean and std.dev: (317.00, 161.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1050) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (126, 2575, 2740) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7968) [M::mem_pestat] mean and std.dev: (2051.87, 1832.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10582) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (342, 726, 2016) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5364) [M::mem_pestat] mean and std.dev: (1057.75, 1033.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7038) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1201.709 CPU sec, 52.989 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036522, 75, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (234, 318, 415) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777) [M::mem_pestat] mean and std.dev: (269.91, 125.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 958) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (347, 2594, 2880) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7946) [M::mem_pestat] mean and std.dev: (1681.33, 1270.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10479) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (412, 844, 1924) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4948) [M::mem_pestat] mean and std.dev: (1060.30, 740.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6460) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.311 CPU sec, 62.274 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 1035852, 69, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (282, 323, 422) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (2, 702) [M::mem_pestat] mean and std.dev: (303.79, 85.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 842) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (455, 2590, 2620) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6950) [M::mem_pestat] mean and std.dev: (1831.72, 1293.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9115) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (391, 455, 1586) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3976) [M::mem_pestat] mean and std.dev: (863.80, 686.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5171) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1254.133 CPU sec, 76.980 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (73, 1035846, 56, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (261, 310, 373) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (37, 597) [M::mem_pestat] mean and std.dev: (282.34, 98.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 709) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1178, 2602, 3575) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8369) [M::mem_pestat] mean and std.dev: (2456.62, 1902.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10766) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (314, 1085, 1565) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4067) [M::mem_pestat] mean and std.dev: (1026.67, 878.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5318) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1212.505 CPU sec, 54.285 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 1036279, 54, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (270, 327, 429) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 747) [M::mem_pestat] mean and std.dev: (294.51, 135.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 906) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (139, 2031, 3610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10552) [M::mem_pestat] mean and std.dev: (2452.54, 2665.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14023) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (330, 448, 1150) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2790) [M::mem_pestat] mean and std.dev: (585.45, 478.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3610) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.728 CPU sec, 62.534 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036025, 56, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (274, 331, 402) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (18, 658) [M::mem_pestat] mean and std.dev: (284.70, 118.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 786) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (490, 2539, 3335) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9025) [M::mem_pestat] mean and std.dev: (2765.46, 2703.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13578) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (338, 430, 2182) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5870) [M::mem_pestat] mean and std.dev: (1083.91, 1229.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7714) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.265 CPU sec, 53.311 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 1035682, 61, 13) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (272, 318, 357) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (102, 527) [M::mem_pestat] mean and std.dev: (297.23, 71.78) [M::mem_pestat] low and high boundaries for proper pairs: (10, 612) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (225, 2588, 3531) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10143) [M::mem_pestat] mean and std.dev: (2628.51, 2598.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13449) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (398, 773, 1935) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5009) [M::mem_pestat] mean and std.dev: (1158.00, 1174.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6546) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1223.374 CPU sec, 69.279 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036282, 71, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (242, 314, 351) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 569) [M::mem_pestat] mean and std.dev: (263.27, 103.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 678) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.80) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (430, 1904, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6985) [M::mem_pestat] mean and std.dev: (1659.11, 1231.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9170) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (407, 880, 1447) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3527) [M::mem_pestat] mean and std.dev: (1010.08, 741.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4567) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1217.079 CPU sec, 53.895 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035518, 68, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 316, 377) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (47, 597) [M::mem_pestat] mean and std.dev: (275.54, 87.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 707) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (615, 2318, 2621) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6633) [M::mem_pestat] mean and std.dev: (1782.78, 1228.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8639) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (355, 959, 1457) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3661) [M::mem_pestat] mean and std.dev: (795.06, 540.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4763) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1260.664 CPU sec, 75.621 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1035531, 68, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (244, 317, 354) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 574) [M::mem_pestat] mean and std.dev: (280.33, 101.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 687) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (196, 2585, 2958) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8482) [M::mem_pestat] mean and std.dev: (1985.83, 1705.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11244) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (369, 779, 1149) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2709) [M::mem_pestat] mean and std.dev: (704.52, 388.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3489) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1216.490 CPU sec, 55.638 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 1035663, 60, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (284, 329, 365) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (122, 527) [M::mem_pestat] mean and std.dev: (303.77, 63.71) [M::mem_pestat] low and high boundaries for proper pairs: (41, 608) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (581, 2576, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6689) [M::mem_pestat] mean and std.dev: (1726.02, 1230.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8725) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (853, 1777, 2315) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5239) [M::mem_pestat] mean and std.dev: (1559.29, 1048.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6701) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.444 CPU sec, 65.455 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 1035627, 68, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (259, 310, 353) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (71, 541) [M::mem_pestat] mean and std.dev: (293.49, 76.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 635) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (835, 2601, 2638) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6244) [M::mem_pestat] mean and std.dev: (1821.45, 1152.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8047) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (406, 915, 2548) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6832) [M::mem_pestat] mean and std.dev: (1580.48, 1432.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8974) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.802 CPU sec, 53.826 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1036086, 58, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 351, 425) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 725) [M::mem_pestat] mean and std.dev: (279.55, 110.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 875) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (230, 2056, 2605) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7355) [M::mem_pestat] mean and std.dev: (1629.56, 1387.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9730) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (635, 1363, 1895) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4415) [M::mem_pestat] mean and std.dev: (1150.42, 825.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5675) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 2666668 sequences (240000120 bp)... [M::mem_process_seqs] Processed 2666668 reads in 1241.549 CPU sec, 72.155 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035900, 62, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (265, 327, 421) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 733) [M::mem_pestat] mean and std.dev: (293.37, 126.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 889) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (624, 2209, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6579) [M::mem_pestat] mean and std.dev: (1759.34, 1171.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8564) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (358, 453, 1337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3295) [M::mem_pestat] mean and std.dev: (900.33, 897.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4489) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.316 CPU sec, 53.859 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 1035606, 68, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (232, 338, 388) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 700) [M::mem_pestat] mean and std.dev: (273.81, 135.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 856) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1031, 2602, 2940) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6758) [M::mem_pestat] mean and std.dev: (2009.78, 1346.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8667) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (454, 849, 1539) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3709) [M::mem_pestat] mean and std.dev: (930.96, 643.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4794) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1214.513 CPU sec, 61.583 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1035272, 76, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (248, 316, 361) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (22, 587) [M::mem_pestat] mean and std.dev: (268.90, 93.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 700) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (270, 2592, 3633) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10359) [M::mem_pestat] mean and std.dev: (2815.97, 2731.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13743) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (415, 1183, 1740) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4390) [M::mem_pestat] mean and std.dev: (1262.04, 1046.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5715) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1256.260 CPU sec, 77.686 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 1035385, 48, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 314, 413) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 745) [M::mem_pestat] mean and std.dev: (249.74, 107.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 911) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (559, 2573, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6727) [M::mem_pestat] mean and std.dev: (1825.59, 1409.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8783) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (480, 1161, 1607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3861) [M::mem_pestat] mean and std.dev: (937.15, 578.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4988) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.731 CPU sec, 54.513 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 1036460, 60, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (262, 320, 383) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (20, 625) [M::mem_pestat] mean and std.dev: (276.36, 107.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 746) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (156, 2072, 2637) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7599) [M::mem_pestat] mean and std.dev: (1745.82, 1688.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10080) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (321, 453, 1370) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3468) [M::mem_pestat] mean and std.dev: (831.52, 740.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4517) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.366 CPU sec, 66.252 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1035506, 75, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (234, 306, 467) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 933) [M::mem_pestat] mean and std.dev: (262.61, 144.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1166) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (330, 1930, 2629) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7227) [M::mem_pestat] mean and std.dev: (1751.49, 1529.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9526) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (388, 889, 1314) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3166) [M::mem_pestat] mean and std.dev: (982.83, 767.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4092) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.602 CPU sec, 53.287 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1036500, 52, 13) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (297, 342, 398) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (95, 600) [M::mem_pestat] mean and std.dev: (316.57, 76.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 701) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (270, 2590, 2975) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8385) [M::mem_pestat] mean and std.dev: (1940.15, 1717.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11090) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (437, 1628, 3346) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9164) [M::mem_pestat] mean and std.dev: (2126.00, 1925.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12073) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.528 CPU sec, 61.813 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035113, 68, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (319, 354, 414) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (129, 604) [M::mem_pestat] mean and std.dev: (337.87, 71.35) [M::mem_pestat] low and high boundaries for proper pairs: (34, 699) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (183, 1910, 2599) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7431) [M::mem_pestat] mean and std.dev: (1429.08, 1113.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9847) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (388, 1266, 1927) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5005) [M::mem_pestat] mean and std.dev: (1111.06, 873.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6544) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.813 CPU sec, 53.411 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036624, 66, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (274, 333, 400) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (22, 652) [M::mem_pestat] mean and std.dev: (309.20, 116.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 778) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (391, 2225, 2607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7039) [M::mem_pestat] mean and std.dev: (1556.64, 1159.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9255) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (629, 1192, 1413) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2981) [M::mem_pestat] mean and std.dev: (1042.00, 476.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3765) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1245.336 CPU sec, 74.349 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035427, 61, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (291, 340, 453) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 777) [M::mem_pestat] mean and std.dev: (305.20, 121.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 939) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (361, 2586, 2926) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8056) [M::mem_pestat] mean and std.dev: (1880.75, 1595.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10621) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (417, 896, 1323) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3135) [M::mem_pestat] mean and std.dev: (870.89, 589.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4041) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.822 CPU sec, 56.008 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1036102, 71, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 317, 422) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 716) [M::mem_pestat] mean and std.dev: (302.06, 119.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 863) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1431, 2590, 3468) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7542) [M::mem_pestat] mean and std.dev: (2135.61, 1516.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9579) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (206, 1106, 2537) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7199) [M::mem_pestat] mean and std.dev: (1205.35, 1098.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9530) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1217.241 CPU sec, 66.854 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036724, 69, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (274, 333, 422) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 718) [M::mem_pestat] mean and std.dev: (291.38, 124.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 866) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (208, 2296, 3605) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10399) [M::mem_pestat] mean and std.dev: (2733.86, 2740.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13796) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (449, 1298, 2006) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5120) [M::mem_pestat] mean and std.dev: (1245.79, 908.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6677) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.926 CPU sec, 53.986 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 1036281, 71, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (243, 337, 646) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1452) [M::mem_pestat] mean and std.dev: (333.24, 249.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1855) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (376, 2585, 2945) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8083) [M::mem_pestat] mean and std.dev: (2008.06, 1673.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10652) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (496, 1264, 1880) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4648) [M::mem_pestat] mean and std.dev: (942.27, 559.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6032) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1217.038 CPU sec, 67.885 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 1035808, 55, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (279, 328, 365) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (107, 537) [M::mem_pestat] mean and std.dev: (308.79, 41.42) [M::mem_pestat] low and high boundaries for proper pairs: (21, 623) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1240, 2594, 2888) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6184) [M::mem_pestat] mean and std.dev: (1980.94, 1081.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7832) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (308, 564, 1166) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2882) [M::mem_pestat] mean and std.dev: (645.58, 494.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3740) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1214.554 CPU sec, 53.608 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1036083, 62, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 331, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 643) [M::mem_pestat] mean and std.dev: (279.60, 116.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 775) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (536, 2587, 2972) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7844) [M::mem_pestat] mean and std.dev: (1842.69, 1349.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10280) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (401, 1294, 3032) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8294) [M::mem_pestat] mean and std.dev: (1634.00, 1480.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10925) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1212.635 CPU sec, 59.576 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036249, 55, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (243, 324, 621) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1377) [M::mem_pestat] mean and std.dev: (360.69, 262.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1755) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (214, 1925, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7414) [M::mem_pestat] mean and std.dev: (1588.23, 1432.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9814) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (345, 923, 1538) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3924) [M::mem_pestat] mean and std.dev: (914.71, 610.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5117) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1269.723 CPU sec, 75.114 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036284, 60, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 327, 380) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (41, 606) [M::mem_pestat] mean and std.dev: (300.82, 98.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 719) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (340, 1639, 2950) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8170) [M::mem_pestat] mean and std.dev: (1846.30, 1695.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10780) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (335, 448, 1386) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3488) [M::mem_pestat] mean and std.dev: (810.29, 765.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4539) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1223.099 CPU sec, 55.942 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036498, 65, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (274, 326, 398) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (26, 646) [M::mem_pestat] mean and std.dev: (289.29, 99.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 770) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (581, 2585, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6674) [M::mem_pestat] mean and std.dev: (1829.80, 1170.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8705) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (371, 839, 2030) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5348) [M::mem_pestat] mean and std.dev: (1036.10, 843.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7007) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1217.309 CPU sec, 68.763 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (76, 1035916, 63, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 326, 367) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (91, 551) [M::mem_pestat] mean and std.dev: (305.86, 69.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 643) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1053, 2592, 2876) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6522) [M::mem_pestat] mean and std.dev: (1904.09, 1206.62) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8345) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (346, 547, 1507) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3829) [M::mem_pestat] mean and std.dev: (838.10, 798.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4990) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1231.694 CPU sec, 54.494 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1037440, 66, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (261, 329, 414) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 720) [M::mem_pestat] mean and std.dev: (292.94, 124.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 873) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1115, 2580, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5597) [M::mem_pestat] mean and std.dev: (1759.23, 1105.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7091) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (312, 439, 1532) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3972) [M::mem_pestat] mean and std.dev: (996.78, 954.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5192) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.420 CPU sec, 66.133 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036151, 66, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (252, 335, 396) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 684) [M::mem_pestat] mean and std.dev: (286.05, 120.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 828) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (323, 2586, 2957) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8225) [M::mem_pestat] mean and std.dev: (1923.36, 1771.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10859) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (399, 1047, 2595) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6987) [M::mem_pestat] mean and std.dev: (1670.43, 1827.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9183) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.821 CPU sec, 53.778 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035188, 69, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (243, 308, 389) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 681) [M::mem_pestat] mean and std.dev: (276.82, 102.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 827) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (433, 2590, 3512) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9670) [M::mem_pestat] mean and std.dev: (2459.14, 2133.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12749) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (675, 794, 1697) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3741) [M::mem_pestat] mean and std.dev: (991.31, 763.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4763) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1270.679 CPU sec, 75.687 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 1036905, 67, 29) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (290, 335, 395) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (80, 605) [M::mem_pestat] mean and std.dev: (310.73, 64.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 710) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1226, 2594, 3638) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8462) [M::mem_pestat] mean and std.dev: (2262.37, 1915.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10874) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (348, 672, 1796) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4692) [M::mem_pestat] mean and std.dev: (1115.28, 1006.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6140) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.507 CPU sec, 55.238 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036521, 64, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (290, 335, 390) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (90, 590) [M::mem_pestat] mean and std.dev: (319.98, 95.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 701) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1232, 2590, 3611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8369) [M::mem_pestat] mean and std.dev: (2139.18, 1835.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10748) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (421, 770, 1562) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3844) [M::mem_pestat] mean and std.dev: (929.86, 606.87) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4985) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1217.462 CPU sec, 66.894 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1035480, 52, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (276, 329, 466) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 846) [M::mem_pestat] mean and std.dev: (303.64, 130.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1036) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1696, 2596, 2624) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4480) [M::mem_pestat] mean and std.dev: (1935.39, 1205.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6758) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (356, 1263, 1852) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4844) [M::mem_pestat] mean and std.dev: (1220.70, 826.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6340) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.952 CPU sec, 53.623 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1036368, 74, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (249, 326, 390) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 672) [M::mem_pestat] mean and std.dev: (278.29, 117.14) [M::mem_pestat] low and high boundaries for proper pairs: (1, 813) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (293, 2589, 2619) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7271) [M::mem_pestat] mean and std.dev: (1819.25, 1265.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9597) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (411, 1033, 2006) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5196) [M::mem_pestat] mean and std.dev: (1277.33, 985.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6791) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1206.461 CPU sec, 62.965 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035457, 64, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (239, 308, 382) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668) [M::mem_pestat] mean and std.dev: (269.49, 115.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 811) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (405, 2585, 2830) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7680) [M::mem_pestat] mean and std.dev: (1811.08, 1445.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10105) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (352, 868, 2173) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5815) [M::mem_pestat] mean and std.dev: (1114.40, 1083.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7636) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1206.805 CPU sec, 53.160 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1036387, 74, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 329, 377) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (71, 581) [M::mem_pestat] mean and std.dev: (308.04, 71.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 683) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (273, 1941, 2923) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8223) [M::mem_pestat] mean and std.dev: (1843.24, 1704.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10873) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (356, 831, 2480) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6728) [M::mem_pestat] mean and std.dev: (1381.78, 1124.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8852) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.245 CPU sec, 59.359 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1036256, 57, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (273, 325, 384) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (51, 606) [M::mem_pestat] mean and std.dev: (291.28, 86.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 717) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (908, 2597, 4005) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10199) [M::mem_pestat] mean and std.dev: (3150.56, 2745.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14132) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (402, 923, 1465) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3591) [M::mem_pestat] mean and std.dev: (877.04, 590.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4654) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1257.708 CPU sec, 77.403 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036085, 57, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (295, 333, 386) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (113, 568) [M::mem_pestat] mean and std.dev: (310.89, 67.13) [M::mem_pestat] low and high boundaries for proper pairs: (22, 659) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (374, 2598, 3902) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10958) [M::mem_pestat] mean and std.dev: (2785.39, 2560.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14486) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (455, 755, 2061) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5273) [M::mem_pestat] mean and std.dev: (1273.70, 1116.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6879) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1219.639 CPU sec, 55.415 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 1036387, 56, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (288, 340, 666) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1422) [M::mem_pestat] mean and std.dev: (401.26, 322.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1800) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1213, 2591, 2849) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6121) [M::mem_pestat] mean and std.dev: (1954.80, 1252.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7757) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (432, 686, 1432) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432) [M::mem_pestat] mean and std.dev: (876.19, 590.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4432) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1217.472 CPU sec, 60.792 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 1035417, 69, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (274, 322, 444) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 784) [M::mem_pestat] mean and std.dev: (265.30, 120.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 954) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (701, 2587, 2987) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7559) [M::mem_pestat] mean and std.dev: (2174.75, 1826.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9845) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (865, 1308, 4746) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 12508) [M::mem_pestat] mean and std.dev: (2507.21, 2413.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 16389) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1212.837 CPU sec, 53.417 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1036967, 58, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (273, 318, 401) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (17, 657) [M::mem_pestat] mean and std.dev: (286.00, 88.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 785) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (818, 2578, 2998) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7358) [M::mem_pestat] mean and std.dev: (2052.15, 1651.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9538) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (425, 1028, 1498) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3644) [M::mem_pestat] mean and std.dev: (1085.05, 733.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4717) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1223.312 CPU sec, 65.901 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1035695, 62, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (251, 301, 800) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1898) [M::mem_pestat] mean and std.dev: (438.05, 432.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2447) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1130, 2602, 2966) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6638) [M::mem_pestat] mean and std.dev: (1898.37, 1245.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8474) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (377, 793, 1402) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3452) [M::mem_pestat] mean and std.dev: (887.46, 816.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4477) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1205.950 CPU sec, 53.217 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1035972, 66, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (291, 329, 404) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (65, 630) [M::mem_pestat] mean and std.dev: (308.71, 89.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 743) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (179, 1481, 2603) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7451) [M::mem_pestat] mean and std.dev: (1554.51, 1474.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9875) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (967, 1270, 1950) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3916) [M::mem_pestat] mean and std.dev: (1309.24, 759.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4899) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1268.671 CPU sec, 75.768 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 1036191, 41, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (293, 347, 503) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 923) [M::mem_pestat] mean and std.dev: (321.09, 145.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1133) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (238, 2167, 2631) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7417) [M::mem_pestat] mean and std.dev: (1596.54, 1202.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9810) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (347, 453, 1404) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3518) [M::mem_pestat] mean and std.dev: (627.05, 452.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4575) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1214.785 CPU sec, 55.932 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1035496, 64, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 316, 367) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (46, 581) [M::mem_pestat] mean and std.dev: (283.90, 113.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 739) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (957, 2600, 3237) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7797) [M::mem_pestat] mean and std.dev: (2126.12, 1414.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10077) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (351, 403, 913) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2037) [M::mem_pestat] mean and std.dev: (534.41, 396.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2599) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1227.411 CPU sec, 63.897 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035816, 56, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (283, 335, 876) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062) [M::mem_pestat] mean and std.dev: (476.29, 407.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2655) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1722, 2599, 4456) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9924) [M::mem_pestat] mean and std.dev: (3191.98, 2613.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13645) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (380, 780, 2365) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6335) [M::mem_pestat] mean and std.dev: (1321.73, 1239.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8320) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.886 CPU sec, 53.830 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 1036338, 55, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (280, 338, 436) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 748) [M::mem_pestat] mean and std.dev: (306.30, 77.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 904) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (407, 2309, 2605) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7001) [M::mem_pestat] mean and std.dev: (1727.04, 1182.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9199) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (326, 779, 1185) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2903) [M::mem_pestat] mean and std.dev: (728.92, 477.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3762) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.988 CPU sec, 66.718 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036794, 59, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (290, 320, 376) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (118, 548) [M::mem_pestat] mean and std.dev: (315.47, 58.77) [M::mem_pestat] low and high boundaries for proper pairs: (32, 634) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (260, 1920, 2618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7334) [M::mem_pestat] mean and std.dev: (1585.25, 1432.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9692) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (316, 449, 1119) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2725) [M::mem_pestat] mean and std.dev: (607.41, 423.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3528) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1203.972 CPU sec, 53.158 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035290, 66, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (238, 307, 382) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 670) [M::mem_pestat] mean and std.dev: (275.23, 111.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 814) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1350, 2602, 5963) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 15189) [M::mem_pestat] mean and std.dev: (3397.55, 2957.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 19802) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (382, 1213, 1904) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4948) [M::mem_pestat] mean and std.dev: (1201.28, 964.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6470) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.062 CPU sec, 58.071 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1035396, 58, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (280, 331, 391) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (58, 613) [M::mem_pestat] mean and std.dev: (310.50, 76.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 724) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (220, 2594, 3629) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10447) [M::mem_pestat] mean and std.dev: (2679.29, 2755.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13856) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (410, 779, 1896) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4868) [M::mem_pestat] mean and std.dev: (1180.42, 1150.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6354) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1261.900 CPU sec, 75.585 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035690, 63, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (256, 334, 443) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 817) [M::mem_pestat] mean and std.dev: (295.36, 132.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1004) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (201, 2586, 2618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7452) [M::mem_pestat] mean and std.dev: (1840.78, 1460.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9869) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (433, 1091, 2111) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5467) [M::mem_pestat] mean and std.dev: (1265.55, 1110.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7145) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.749 CPU sec, 55.846 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036141, 58, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (207, 310, 371) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 699) [M::mem_pestat] mean and std.dev: (276.51, 120.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 863) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (280, 2580, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7273) [M::mem_pestat] mean and std.dev: (1845.54, 1448.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9604) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (397, 1129, 2416) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6454) [M::mem_pestat] mean and std.dev: (1336.56, 1246.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8473) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.042 CPU sec, 62.594 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1035650, 61, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (268, 325, 373) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (58, 583) [M::mem_pestat] mean and std.dev: (287.80, 77.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 688) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (478, 2579, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6871) [M::mem_pestat] mean and std.dev: (1893.08, 1173.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9002) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (376, 774, 1453) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3607) [M::mem_pestat] mean and std.dev: (955.67, 712.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4684) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.852 CPU sec, 53.466 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035900, 73, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (289, 341, 821) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1885) [M::mem_pestat] mean and std.dev: (396.14, 296.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2417) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (297, 2582, 2819) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7863) [M::mem_pestat] mean and std.dev: (1837.56, 1559.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10385) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (295, 427, 1671) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4423) [M::mem_pestat] mean and std.dev: (656.57, 669.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5799) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.220 CPU sec, 69.512 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1035731, 64, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (238, 325, 558) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1198) [M::mem_pestat] mean and std.dev: (327.54, 230.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1518) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (638, 2596, 3415) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8969) [M::mem_pestat] mean and std.dev: (2391.39, 2008.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11746) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (290, 439, 2016) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5468) [M::mem_pestat] mean and std.dev: (1148.73, 1105.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7194) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.536 CPU sec, 53.785 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035076, 44, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (182, 339, 372) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 752) [M::mem_pestat] mean and std.dev: (266.93, 167.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 942) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (660, 2590, 2978) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7614) [M::mem_pestat] mean and std.dev: (1954.51, 1271.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9932) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (448, 548, 1286) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2962) [M::mem_pestat] mean and std.dev: (787.80, 571.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3800) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1258.066 CPU sec, 75.050 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035603, 55, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (292, 352, 838) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1930) [M::mem_pestat] mean and std.dev: (497.62, 389.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2476) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (270, 1911, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7308) [M::mem_pestat] mean and std.dev: (1621.37, 1319.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9654) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (308, 788, 1414) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3626) [M::mem_pestat] mean and std.dev: (793.64, 619.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4732) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.242 CPU sec, 56.122 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1036154, 55, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (206, 325, 404) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 800) [M::mem_pestat] mean and std.dev: (262.10, 110.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 998) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (152, 1992, 2628) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7580) [M::mem_pestat] mean and std.dev: (1588.98, 1441.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10056) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (358, 929, 1489) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3751) [M::mem_pestat] mean and std.dev: (1086.87, 854.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4882) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 2666668 sequences (240000120 bp)... [M::mem_process_seqs] Processed 2666668 reads in 1228.858 CPU sec, 69.505 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1034699, 81, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (266, 320, 376) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (46, 596) [M::mem_pestat] mean and std.dev: (280.81, 95.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 706) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (267, 2592, 2902) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8172) [M::mem_pestat] mean and std.dev: (1961.63, 1720.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10807) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (384, 726, 1585) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3987) [M::mem_pestat] mean and std.dev: (1072.41, 914.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5188) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.893 CPU sec, 53.814 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 1035355, 62, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (287, 324, 376) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (109, 554) [M::mem_pestat] mean and std.dev: (308.44, 65.90) [M::mem_pestat] low and high boundaries for proper pairs: (20, 643) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (438, 2118, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6963) [M::mem_pestat] mean and std.dev: (1779.09, 1315.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9138) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (422, 926, 1245) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2891) [M::mem_pestat] mean and std.dev: (857.63, 521.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3714) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1212.619 CPU sec, 65.741 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1035503, 67, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (263, 316, 350) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (89, 524) [M::mem_pestat] mean and std.dev: (301.14, 62.84) [M::mem_pestat] low and high boundaries for proper pairs: (2, 611) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (429, 2589, 2630) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7032) [M::mem_pestat] mean and std.dev: (1877.07, 1364.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9233) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (391, 790, 1915) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4963) [M::mem_pestat] mean and std.dev: (1251.62, 1189.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6487) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.818 CPU sec, 53.476 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036868, 51, 30) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (277, 337, 378) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (75, 580) [M::mem_pestat] mean and std.dev: (311.07, 65.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 681) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (162, 1650, 2603) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7485) [M::mem_pestat] mean and std.dev: (1435.35, 1300.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9926) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (228, 882, 1780) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4884) [M::mem_pestat] mean and std.dev: (1068.30, 1229.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6436) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.999 CPU sec, 57.446 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035661, 69, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (290, 326, 412) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (46, 656) [M::mem_pestat] mean and std.dev: (292.41, 97.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 778) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (444, 2598, 2618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6966) [M::mem_pestat] mean and std.dev: (1993.68, 1443.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9140) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (342, 1023, 1443) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3645) [M::mem_pestat] mean and std.dev: (958.21, 820.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4746) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1231.870 CPU sec, 78.354 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035750, 70, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (276, 336, 408) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (12, 672) [M::mem_pestat] mean and std.dev: (289.33, 108.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 804) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1233, 2580, 2640) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5454) [M::mem_pestat] mean and std.dev: (2024.85, 1233.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6958) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (364, 528, 2206) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5890) [M::mem_pestat] mean and std.dev: (1066.59, 996.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7732) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1210.148 CPU sec, 54.082 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036111, 58, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (254, 332, 384) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 644) [M::mem_pestat] mean and std.dev: (270.02, 109.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 774) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (139, 2066, 2604) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7534) [M::mem_pestat] mean and std.dev: (1647.29, 1503.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9999) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (373, 1135, 1907) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4975) [M::mem_pestat] mean and std.dev: (964.25, 631.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6509) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.053 CPU sec, 64.794 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 1035596, 64, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 321, 472) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 882) [M::mem_pestat] mean and std.dev: (293.12, 108.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1087) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (616, 2591, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6604) [M::mem_pestat] mean and std.dev: (1859.19, 1284.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8600) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (324, 440, 903) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2061) [M::mem_pestat] mean and std.dev: (585.36, 469.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2640) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1197.590 CPU sec, 52.878 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 1036336, 75, 13) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (270, 326, 372) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (66, 576) [M::mem_pestat] mean and std.dev: (308.30, 77.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 678) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1030, 2591, 2850) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6490) [M::mem_pestat] mean and std.dev: (1966.66, 1213.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8310) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (229, 845, 1577) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4273) [M::mem_pestat] mean and std.dev: (834.38, 635.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5621) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.967 CPU sec, 68.060 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1035557, 63, 29) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (220, 297, 376) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 688) [M::mem_pestat] mean and std.dev: (253.81, 101.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 844) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (278, 2261, 2607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7265) [M::mem_pestat] mean and std.dev: (1724.52, 1369.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9594) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (391, 918, 3030) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8308) [M::mem_pestat] mean and std.dev: (1599.00, 1663.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10947) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.674 CPU sec, 53.598 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036528, 55, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (269, 331, 889) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2129) [M::mem_pestat] mean and std.dev: (479.79, 426.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2749) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1868, 2600, 2910) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4994) [M::mem_pestat] mean and std.dev: (1958.43, 1081.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6285) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (302, 526, 1551) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4049) [M::mem_pestat] mean and std.dev: (697.47, 655.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5298) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1267.090 CPU sec, 75.896 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036062, 59, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (249, 315, 403) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 711) [M::mem_pestat] mean and std.dev: (283.77, 108.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 865) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (510, 2595, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6831) [M::mem_pestat] mean and std.dev: (1803.02, 1259.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8938) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (442, 1183, 1638) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4030) [M::mem_pestat] mean and std.dev: (1301.10, 938.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5226) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1221.336 CPU sec, 56.019 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035309, 61, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (243, 318, 514) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1056) [M::mem_pestat] mean and std.dev: (298.98, 207.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1327) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (298, 2581, 2785) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7759) [M::mem_pestat] mean and std.dev: (1827.86, 1528.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10246) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (449, 966, 1292) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2978) [M::mem_pestat] mean and std.dev: (944.68, 562.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3821) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1222.200 CPU sec, 67.421 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035980, 57, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (229, 323, 375) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 667) [M::mem_pestat] mean and std.dev: (275.14, 117.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 813) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (592, 2593, 2620) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6676) [M::mem_pestat] mean and std.dev: (1865.94, 1337.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8704) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (380, 880, 1702) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4346) [M::mem_pestat] mean and std.dev: (1161.80, 915.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5668) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.604 CPU sec, 53.644 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1036560, 68, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 317, 670) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1476) [M::mem_pestat] mean and std.dev: (391.30, 332.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1879) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.41, 12.80) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (298, 2351, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7243) [M::mem_pestat] mean and std.dev: (1731.85, 1572.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9558) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (381, 793, 1522) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3804) [M::mem_pestat] mean and std.dev: (942.17, 833.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4945) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.351 CPU sec, 66.206 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035378, 57, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (270, 304, 384) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (42, 612) [M::mem_pestat] mean and std.dev: (283.38, 92.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 726) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (152, 2180, 2894) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8378) [M::mem_pestat] mean and std.dev: (1977.45, 2022.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11120) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (461, 928, 1883) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4727) [M::mem_pestat] mean and std.dev: (1014.89, 710.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6149) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1204.299 CPU sec, 53.154 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1035671, 53, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (248, 317, 362) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (20, 590) [M::mem_pestat] mean and std.dev: (263.52, 104.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 704) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (370, 2575, 2607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7081) [M::mem_pestat] mean and std.dev: (1658.44, 1147.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9318) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (454, 1043, 1842) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4618) [M::mem_pestat] mean and std.dev: (1255.65, 1049.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6006) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1202.206 CPU sec, 55.813 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035093, 65, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (240, 316, 382) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 666) [M::mem_pestat] mean and std.dev: (278.58, 119.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 808) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (445, 2597, 3490) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9580) [M::mem_pestat] mean and std.dev: (2768.77, 2585.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13112) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (410, 740, 1449) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3527) [M::mem_pestat] mean and std.dev: (900.00, 774.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4566) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1250.651 CPU sec, 74.835 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036670, 52, 4) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (242, 318, 352) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (22, 572) [M::mem_pestat] mean and std.dev: (278.55, 77.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 682) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (432, 2594, 3014) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8178) [M::mem_pestat] mean and std.dev: (2043.29, 1601.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10760) [M::mem_pestat] skip orientation RR as there are not enough pairs [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_process_seqs] Processed 2666668 reads in 1218.336 CPU sec, 55.880 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 1035965, 74, 30) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (212, 308, 599) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1373) [M::mem_pestat] mean and std.dev: (364.12, 321.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1760) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (272, 2585, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7304) [M::mem_pestat] mean and std.dev: (1734.66, 1266.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9648) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (351, 1204, 1566) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3996) [M::mem_pestat] mean and std.dev: (931.59, 637.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5211) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.705 CPU sec, 63.628 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1035127, 76, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 319, 366) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (93, 548) [M::mem_pestat] mean and std.dev: (302.73, 68.51) [M::mem_pestat] low and high boundaries for proper pairs: (2, 639) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (205, 1892, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7441) [M::mem_pestat] mean and std.dev: (1509.43, 1401.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9853) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (332, 540, 1143) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2765) [M::mem_pestat] mean and std.dev: (615.22, 461.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3576) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1200.659 CPU sec, 53.012 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1036826, 59, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (240, 319, 381) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 663) [M::mem_pestat] mean and std.dev: (266.15, 103.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 804) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1876, 2600, 3749) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7495) [M::mem_pestat] mean and std.dev: (2483.60, 1572.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9368) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (366, 841, 1694) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4350) [M::mem_pestat] mean and std.dev: (965.91, 925.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5678) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.613 CPU sec, 66.824 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036245, 69, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (224, 320, 467) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 953) [M::mem_pestat] mean and std.dev: (293.86, 160.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1196) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1078, 2572, 2607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5665) [M::mem_pestat] mean and std.dev: (1837.72, 1137.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7194) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (373, 913, 1614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4096) [M::mem_pestat] mean and std.dev: (1039.12, 861.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5337) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1200.088 CPU sec, 53.153 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035322, 52, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 301, 350) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (41, 556) [M::mem_pestat] mean and std.dev: (267.23, 89.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 659) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (245, 2513, 2837) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8021) [M::mem_pestat] mean and std.dev: (1854.84, 1656.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10613) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (424, 926, 1763) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4441) [M::mem_pestat] mean and std.dev: (860.26, 623.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5780) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1261.661 CPU sec, 74.918 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1035976, 56, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (273, 325, 362) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (95, 540) [M::mem_pestat] mean and std.dev: (308.71, 69.08) [M::mem_pestat] low and high boundaries for proper pairs: (6, 629) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (433, 2576, 2685) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7189) [M::mem_pestat] mean and std.dev: (1798.26, 1314.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9441) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (302, 490, 1655) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4361) [M::mem_pestat] mean and std.dev: (799.61, 749.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5714) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1206.544 CPU sec, 55.616 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035663, 81, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (272, 337, 459) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833) [M::mem_pestat] mean and std.dev: (335.59, 150.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1020) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (494, 2593, 2928) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7796) [M::mem_pestat] mean and std.dev: (2124.89, 1655.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10230) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (403, 1017, 2386) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6352) [M::mem_pestat] mean and std.dev: (1404.69, 1219.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8335) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.459 CPU sec, 65.896 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035987, 60, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (287, 349, 670) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1436) [M::mem_pestat] mean and std.dev: (353.04, 239.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1819) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (200, 2202, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7448) [M::mem_pestat] mean and std.dev: (1697.51, 1309.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9864) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (450, 1129, 1443) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3429) [M::mem_pestat] mean and std.dev: (979.16, 651.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4422) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1200.313 CPU sec, 53.111 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1036262, 61, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (245, 336, 766) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1808) [M::mem_pestat] mean and std.dev: (423.75, 375.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2329) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (850, 2594, 3619) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9157) [M::mem_pestat] mean and std.dev: (3080.59, 2872.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14570) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (371, 1217, 2691) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7331) [M::mem_pestat] mean and std.dev: (1711.46, 1816.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9651) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1212.591 CPU sec, 66.414 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (71, 1036241, 57, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (268, 325, 380) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (44, 604) [M::mem_pestat] mean and std.dev: (299.93, 90.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 716) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (203, 2573, 2856) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8162) [M::mem_pestat] mean and std.dev: (1839.65, 1554.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10815) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (965, 1198, 2447) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5411) [M::mem_pestat] mean and std.dev: (1502.61, 944.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6893) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1192.433 CPU sec, 52.856 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 1036006, 51, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (248, 338, 372) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 620) [M::mem_pestat] mean and std.dev: (284.25, 98.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 744) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (377, 2059, 2962) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8132) [M::mem_pestat] mean and std.dev: (1859.94, 1709.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10717) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (410, 1099, 1561) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3863) [M::mem_pestat] mean and std.dev: (1097.75, 835.09) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5014) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1188.109 CPU sec, 53.802 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036612, 60, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (244, 314, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 649) [M::mem_pestat] mean and std.dev: (271.73, 121.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 784) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (614, 2599, 2717) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6923) [M::mem_pestat] mean and std.dev: (1929.98, 1372.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9026) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (324, 898, 1507) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3873) [M::mem_pestat] mean and std.dev: (921.79, 708.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5056) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1252.053 CPU sec, 74.514 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035948, 59, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (262, 316, 510) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1006) [M::mem_pestat] mean and std.dev: (326.83, 161.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1254) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (320, 1911, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7199) [M::mem_pestat] mean and std.dev: (1625.78, 1291.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9492) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (349, 918, 2026) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5380) [M::mem_pestat] mean and std.dev: (1275.50, 1153.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7057) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1204.155 CPU sec, 55.571 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1037004, 48, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (285, 319, 365) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (125, 525) [M::mem_pestat] mean and std.dev: (311.68, 49.21) [M::mem_pestat] low and high boundaries for proper pairs: (45, 605) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (333, 1779, 2630) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7224) [M::mem_pestat] mean and std.dev: (1599.31, 1257.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9521) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (314, 376, 2189) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5939) [M::mem_pestat] mean and std.dev: (1405.06, 1741.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8371) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1209.120 CPU sec, 67.178 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 1036199, 59, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (271, 319, 392) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (29, 634) [M::mem_pestat] mean and std.dev: (274.74, 82.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 755) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (460, 2570, 2607) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6901) [M::mem_pestat] mean and std.dev: (1812.09, 1326.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9048) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (423, 1034, 2842) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7680) [M::mem_pestat] mean and std.dev: (1893.05, 2113.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10347) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1194.280 CPU sec, 52.802 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035191, 55, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 323, 650) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1422) [M::mem_pestat] mean and std.dev: (348.44, 251.44) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1808) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (432, 2592, 3632) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10032) [M::mem_pestat] mean and std.dev: (2492.11, 2338.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13232) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (736, 1004, 1470) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2938) [M::mem_pestat] mean and std.dev: (883.82, 408.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3672) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.170 CPU sec, 62.636 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1036759, 83, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 321, 711) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1613) [M::mem_pestat] mean and std.dev: (372.36, 281.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2064) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1198, 2599, 2941) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6427) [M::mem_pestat] mean and std.dev: (2042.76, 1378.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8170) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (394, 623, 1109) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2539) [M::mem_pestat] mean and std.dev: (748.74, 473.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3254) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1197.577 CPU sec, 52.781 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035996, 69, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (249, 318, 366) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (15, 600) [M::mem_pestat] mean and std.dev: (287.36, 99.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 717) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (384, 2584, 2888) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7896) [M::mem_pestat] mean and std.dev: (1839.26, 1502.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10400) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (473, 1317, 1889) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4721) [M::mem_pestat] mean and std.dev: (1139.94, 706.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6137) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1246.143 CPU sec, 74.463 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036464, 47, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (293, 366, 906) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2132) [M::mem_pestat] mean and std.dev: (499.94, 391.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2745) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1064, 1916, 2828) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6356) [M::mem_pestat] mean and std.dev: (1879.27, 1244.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8120) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (550, 940, 1357) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2971) [M::mem_pestat] mean and std.dev: (951.61, 520.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3778) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1202.041 CPU sec, 55.389 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 1035685, 51, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 322, 378) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (45, 600) [M::mem_pestat] mean and std.dev: (278.91, 85.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 711) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (376, 2589, 3632) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10144) [M::mem_pestat] mean and std.dev: (2843.65, 2801.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14048) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (393, 883, 1338) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3228) [M::mem_pestat] mean and std.dev: (860.25, 535.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4173) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1211.688 CPU sec, 66.201 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035486, 53, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (248, 332, 395) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 689) [M::mem_pestat] mean and std.dev: (282.10, 122.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 836) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (477, 2084, 2601) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6849) [M::mem_pestat] mean and std.dev: (1721.67, 1231.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8973) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (375, 881, 1237) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2961) [M::mem_pestat] mean and std.dev: (894.45, 629.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3823) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1192.319 CPU sec, 52.631 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 1035619, 68, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (265, 328, 489) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 937) [M::mem_pestat] mean and std.dev: (289.91, 155.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1161) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (702, 2585, 3575) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9321) [M::mem_pestat] mean and std.dev: (2449.61, 2213.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12194) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (381, 853, 1304) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3150) [M::mem_pestat] mean and std.dev: (795.22, 517.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4073) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1205.775 CPU sec, 64.851 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035489, 60, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (215, 291, 340) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 590) [M::mem_pestat] mean and std.dev: (255.77, 104.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 715) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (295, 2582, 2982) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8356) [M::mem_pestat] mean and std.dev: (2165.40, 2054.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11043) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (287, 397, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7244) [M::mem_pestat] mean and std.dev: (942.39, 938.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9563) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1188.983 CPU sec, 52.566 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 1035827, 58, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (230, 303, 386) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 698) [M::mem_pestat] mean and std.dev: (271.67, 111.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 854) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (336, 2141, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7155) [M::mem_pestat] mean and std.dev: (1696.59, 1253.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9428) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (620, 1112, 1843) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4289) [M::mem_pestat] mean and std.dev: (957.50, 563.49) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5512) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1177.177 CPU sec, 52.596 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036627, 61, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (284, 342, 674) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1454) [M::mem_pestat] mean and std.dev: (399.54, 283.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1844) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (376, 1903, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7066) [M::mem_pestat] mean and std.dev: (1629.78, 1288.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9296) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (249, 1034, 1840) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5022) [M::mem_pestat] mean and std.dev: (919.80, 857.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6613) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1229.211 CPU sec, 73.927 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1035468, 61, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (280, 323, 361) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (118, 523) [M::mem_pestat] mean and std.dev: (307.56, 49.23) [M::mem_pestat] low and high boundaries for proper pairs: (37, 604) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (171, 2452, 3469) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10065) [M::mem_pestat] mean and std.dev: (2555.67, 2699.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13363) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (383, 991, 1342) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3260) [M::mem_pestat] mean and std.dev: (990.29, 743.42) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4219) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1194.292 CPU sec, 54.961 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (41, 1036530, 63, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (260, 313, 384) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (12, 632) [M::mem_pestat] mean and std.dev: (276.69, 114.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 756) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (707, 2591, 2928) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7370) [M::mem_pestat] mean and std.dev: (1871.26, 1330.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9591) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (351, 582, 1373) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3417) [M::mem_pestat] mean and std.dev: (926.60, 834.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4439) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1200.618 CPU sec, 65.878 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035749, 66, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (303, 341, 563) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1083) [M::mem_pestat] mean and std.dev: (351.96, 157.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1343) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (322, 2582, 2698) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7450) [M::mem_pestat] mean and std.dev: (1844.66, 1410.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9826) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (553, 990, 1985) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4849) [M::mem_pestat] mean and std.dev: (1151.00, 790.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6281) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1195.172 CPU sec, 52.915 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036636, 53, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (285, 330, 558) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1104) [M::mem_pestat] mean and std.dev: (339.77, 150.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1377) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (668, 2593, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6497) [M::mem_pestat] mean and std.dev: (2017.31, 1336.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8440) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (356, 473, 1014) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2330) [M::mem_pestat] mean and std.dev: (602.05, 339.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2988) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1191.233 CPU sec, 64.006 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035749, 52, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (271, 329, 596) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1246) [M::mem_pestat] mean and std.dev: (344.68, 204.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1571) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (331, 1933, 2964) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8230) [M::mem_pestat] mean and std.dev: (1984.48, 1819.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10863) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (414, 1350, 2621) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7035) [M::mem_pestat] mean and std.dev: (1688.45, 1525.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9242) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1186.874 CPU sec, 52.359 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1036129, 64, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (289, 347, 427) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (13, 703) [M::mem_pestat] mean and std.dev: (303.29, 116.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 841) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (667, 2598, 3630) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9556) [M::mem_pestat] mean and std.dev: (2716.00, 2423.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12519) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (232, 532, 1413) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3775) [M::mem_pestat] mean and std.dev: (889.22, 871.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4956) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.709 CPU sec, 73.567 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036088, 79, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (266, 348, 930) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2258) [M::mem_pestat] mean and std.dev: (472.27, 426.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2922) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.80) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (248, 2521, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7352) [M::mem_pestat] mean and std.dev: (1908.68, 1604.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9720) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (401, 971, 1208) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2822) [M::mem_pestat] mean and std.dev: (895.42, 569.70) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3629) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1192.475 CPU sec, 54.731 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (68, 1036401, 62, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (244, 326, 368) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 616) [M::mem_pestat] mean and std.dev: (275.57, 121.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 760) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1061, 2590, 2957) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6749) [M::mem_pestat] mean and std.dev: (1929.81, 1368.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8645) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (340, 516, 2101) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5623) [M::mem_pestat] mean and std.dev: (1216.68, 1295.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7384) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1187.316 CPU sec, 61.897 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1036845, 61, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (281, 316, 421) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701) [M::mem_pestat] mean and std.dev: (284.43, 113.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 841) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1537, 2591, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4768) [M::mem_pestat] mean and std.dev: (2034.59, 1045.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6218) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (393, 421, 1339) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3231) [M::mem_pestat] mean and std.dev: (795.33, 694.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4177) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1177.453 CPU sec, 52.073 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036670, 57, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (224, 301, 359) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 629) [M::mem_pestat] mean and std.dev: (260.35, 115.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 764) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (418, 2586, 2970) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8074) [M::mem_pestat] mean and std.dev: (2008.25, 1590.16) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10626) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (739, 1290, 2087) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4783) [M::mem_pestat] mean and std.dev: (1421.12, 991.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6131) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1195.249 CPU sec, 63.417 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035999, 60, 29) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (285, 337, 388) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (79, 594) [M::mem_pestat] mean and std.dev: (313.84, 61.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 697) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (211, 2589, 2622) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7444) [M::mem_pestat] mean and std.dev: (1774.87, 1768.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9855) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (456, 1053, 1628) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3972) [M::mem_pestat] mean and std.dev: (1041.74, 644.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5144) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1182.186 CPU sec, 52.032 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1037213, 56, 26) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (237, 316, 388) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690) [M::mem_pestat] mean and std.dev: (275.66, 123.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 841) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (127, 2587, 2890) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8416) [M::mem_pestat] mean and std.dev: (2009.08, 1854.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11179) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (456, 1265, 2049) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5235) [M::mem_pestat] mean and std.dev: (1253.74, 1005.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6828) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1177.755 CPU sec, 51.928 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036284, 57, 13) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (275, 323, 359) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (107, 527) [M::mem_pestat] mean and std.dev: (306.80, 69.48) [M::mem_pestat] low and high boundaries for proper pairs: (23, 611) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (258, 2585, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7320) [M::mem_pestat] mean and std.dev: (1834.87, 1529.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9674) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (408, 535, 2068) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5388) [M::mem_pestat] mean and std.dev: (1136.00, 985.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7048) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1216.224 CPU sec, 73.663 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036171, 61, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (283, 336, 363) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (123, 523) [M::mem_pestat] mean and std.dev: (312.27, 67.57) [M::mem_pestat] low and high boundaries for proper pairs: (42, 603) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (130, 1220, 2876) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8368) [M::mem_pestat] mean and std.dev: (1662.88, 1835.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11114) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (396, 1051, 1826) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4686) [M::mem_pestat] mean and std.dev: (1327.52, 1134.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6116) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1179.381 CPU sec, 54.183 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035884, 53, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (281, 339, 431) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 731) [M::mem_pestat] mean and std.dev: (294.57, 135.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 881) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (432, 2599, 2950) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7986) [M::mem_pestat] mean and std.dev: (2177.67, 1817.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10504) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (328, 846, 1343) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3373) [M::mem_pestat] mean and std.dev: (864.05, 608.28) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4388) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1179.323 CPU sec, 58.885 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1035434, 71, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (235, 332, 366) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 628) [M::mem_pestat] mean and std.dev: (285.40, 107.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 759) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (457, 2588, 2886) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7744) [M::mem_pestat] mean and std.dev: (1733.34, 1417.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10173) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (585, 1554, 2000) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4830) [M::mem_pestat] mean and std.dev: (1452.13, 914.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6245) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1178.532 CPU sec, 52.081 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035983, 51, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (295, 346, 386) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (113, 568) [M::mem_pestat] mean and std.dev: (323.54, 47.03) [M::mem_pestat] low and high boundaries for proper pairs: (22, 659) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1657, 2595, 2623) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4555) [M::mem_pestat] mean and std.dev: (2156.94, 1171.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6842) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (417, 840, 1707) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4287) [M::mem_pestat] mean and std.dev: (984.00, 672.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5577) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1183.417 CPU sec, 61.734 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 1036742, 50, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 335, 381) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (30, 615) [M::mem_pestat] mean and std.dev: (277.17, 100.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 732) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (664, 2595, 2673) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6691) [M::mem_pestat] mean and std.dev: (1908.51, 1139.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8700) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (326, 403, 1564) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4040) [M::mem_pestat] mean and std.dev: (613.50, 486.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5278) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1169.877 CPU sec, 51.669 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (66, 1035889, 54, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (271, 333, 384) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (45, 610) [M::mem_pestat] mean and std.dev: (315.46, 70.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 723) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (334, 2030, 2615) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7177) [M::mem_pestat] mean and std.dev: (1568.22, 1282.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9458) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (396, 1010, 2568) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6912) [M::mem_pestat] mean and std.dev: (1273.16, 1262.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9084) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.963 CPU sec, 73.488 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035301, 59, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (284, 321, 350) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (152, 482) [M::mem_pestat] mean and std.dev: (316.83, 57.24) [M::mem_pestat] low and high boundaries for proper pairs: (86, 548) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (242, 2239, 2872) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8132) [M::mem_pestat] mean and std.dev: (1602.68, 1436.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10762) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (423, 1058, 2595) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6939) [M::mem_pestat] mean and std.dev: (1425.47, 1263.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9111) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1181.082 CPU sec, 54.515 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1035081, 58, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (231, 305, 352) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 594) [M::mem_pestat] mean and std.dev: (266.25, 98.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 715) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (343, 2514, 3657) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10285) [M::mem_pestat] mean and std.dev: (2870.69, 2856.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14297) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (246, 434, 1023) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2577) [M::mem_pestat] mean and std.dev: (615.39, 539.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3354) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1180.436 CPU sec, 57.184 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035684, 63, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (228, 301, 362) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 630) [M::mem_pestat] mean and std.dev: (277.91, 88.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 764) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (405, 1926, 2618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7044) [M::mem_pestat] mean and std.dev: (1612.77, 1329.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9257) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (383, 1118, 1862) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4820) [M::mem_pestat] mean and std.dev: (1304.59, 1074.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6299) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1171.824 CPU sec, 51.678 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035668, 63, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (222, 310, 378) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690) [M::mem_pestat] mean and std.dev: (257.67, 108.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 846) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (331, 2117, 2621) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7201) [M::mem_pestat] mean and std.dev: (1798.70, 1430.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9491) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (375, 516, 1075) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2475) [M::mem_pestat] mean and std.dev: (768.05, 586.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3175) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1182.346 CPU sec, 62.937 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1035922, 71, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (285, 332, 760) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1710) [M::mem_pestat] mean and std.dev: (437.64, 354.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2185) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (231, 2572, 2760) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7818) [M::mem_pestat] mean and std.dev: (1863.66, 1630.38) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10347) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (360, 1222, 1771) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4593) [M::mem_pestat] mean and std.dev: (1060.61, 950.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6004) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1172.776 CPU sec, 51.964 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035492, 61, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (205, 303, 384) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 742) [M::mem_pestat] mean and std.dev: (250.76, 123.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 921) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (124, 1930, 2938) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8566) [M::mem_pestat] mean and std.dev: (2019.80, 2201.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11380) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (412, 610, 1771) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4489) [M::mem_pestat] mean and std.dev: (1016.35, 833.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5848) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1172.079 CPU sec, 51.660 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1035884, 66, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (246, 320, 485) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 963) [M::mem_pestat] mean and std.dev: (289.11, 143.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1202) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (580, 2355, 2619) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6697) [M::mem_pestat] mean and std.dev: (1771.18, 1164.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8736) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (371, 936, 1626) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4136) [M::mem_pestat] mean and std.dev: (863.29, 799.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5391) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1218.581 CPU sec, 73.064 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035521, 62, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (291, 334, 629) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1305) [M::mem_pestat] mean and std.dev: (338.62, 158.40) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1643) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1299, 2589, 2652) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5358) [M::mem_pestat] mean and std.dev: (1882.02, 1166.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6711) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (543, 1446, 2056) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5082) [M::mem_pestat] mean and std.dev: (1276.74, 780.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6595) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1175.126 CPU sec, 54.061 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1036860, 56, 29) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (282, 340, 403) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (40, 645) [M::mem_pestat] mean and std.dev: (301.34, 81.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 766) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (444, 2578, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6963) [M::mem_pestat] mean and std.dev: (1621.21, 1154.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9136) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (393, 931, 1630) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4104) [M::mem_pestat] mean and std.dev: (977.76, 887.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5341) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1181.233 CPU sec, 61.514 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035439, 52, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (266, 321, 354) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (90, 530) [M::mem_pestat] mean and std.dev: (294.67, 64.76) [M::mem_pestat] low and high boundaries for proper pairs: (2, 618) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (442, 2590, 2623) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6985) [M::mem_pestat] mean and std.dev: (1810.00, 1309.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9166) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (825, 1049, 3516) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8898) [M::mem_pestat] mean and std.dev: (1916.11, 1902.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11589) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1171.843 CPU sec, 51.726 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036644, 67, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (241, 325, 445) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 853) [M::mem_pestat] mean and std.dev: (315.83, 165.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1057) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (257, 1912, 2610) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7316) [M::mem_pestat] mean and std.dev: (1718.97, 1408.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9669) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (405, 1354, 2928) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7974) [M::mem_pestat] mean and std.dev: (1958.95, 1992.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10497) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1178.887 CPU sec, 62.347 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035457, 52, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (263, 330, 565) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1169) [M::mem_pestat] mean and std.dev: (322.19, 193.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1471) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (510, 2142, 3052) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8136) [M::mem_pestat] mean and std.dev: (2113.02, 1888.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10678) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (393, 971, 1749) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4461) [M::mem_pestat] mean and std.dev: (955.69, 658.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5817) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1171.927 CPU sec, 51.672 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1034971, 67, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (286, 340, 391) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (76, 601) [M::mem_pestat] mean and std.dev: (311.63, 65.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 706) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (143, 1953, 2619) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7571) [M::mem_pestat] mean and std.dev: (1619.23, 1598.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10047) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (342, 422, 1278) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3150) [M::mem_pestat] mean and std.dev: (708.84, 580.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4086) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1220.681 CPU sec, 73.451 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 1035755, 47, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (252, 338, 366) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 594) [M::mem_pestat] mean and std.dev: (301.54, 81.71) [M::mem_pestat] low and high boundaries for proper pairs: (1, 708) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (567, 2597, 3708) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9990) [M::mem_pestat] mean and std.dev: (2879.30, 2736.34) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13825) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (379, 711, 2486) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6700) [M::mem_pestat] mean and std.dev: (1297.96, 1334.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8807) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1180.079 CPU sec, 54.422 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1036558, 48, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (273, 327, 1135) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2859) [M::mem_pestat] mean and std.dev: (611.05, 613.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3721) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (263, 1914, 3480) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9914) [M::mem_pestat] mean and std.dev: (2378.12, 2584.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13131) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (384, 1013, 1892) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4908) [M::mem_pestat] mean and std.dev: (1180.81, 965.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6416) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1187.333 CPU sec, 62.439 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1035457, 53, 32) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (270, 310, 384) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (42, 612) [M::mem_pestat] mean and std.dev: (285.02, 93.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 726) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (328, 2588, 3631) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10237) [M::mem_pestat] mean and std.dev: (2657.21, 2649.20) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13540) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (310, 449, 1592) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4156) [M::mem_pestat] mean and std.dev: (812.19, 733.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5438) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1168.782 CPU sec, 51.539 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1036132, 61, 10) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 317, 374) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (53, 588) [M::mem_pestat] mean and std.dev: (297.48, 89.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 695) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1050, 2599, 2891) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6573) [M::mem_pestat] mean and std.dev: (2031.68, 1311.63) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8414) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (439, 1482, 3495) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9607) [M::mem_pestat] mean and std.dev: (2158.10, 2087.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12663) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1180.831 CPU sec, 61.559 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035906, 52, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (239, 315, 350) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (17, 572) [M::mem_pestat] mean and std.dev: (269.67, 97.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 683) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1885, 2595, 3730) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7420) [M::mem_pestat] mean and std.dev: (2520.56, 1520.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9265) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (352, 931, 1487) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3757) [M::mem_pestat] mean and std.dev: (886.62, 609.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4892) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1171.733 CPU sec, 51.865 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1035784, 48, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (277, 330, 481) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 889) [M::mem_pestat] mean and std.dev: (310.84, 141.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1093) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1054, 2589, 2616) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5740) [M::mem_pestat] mean and std.dev: (1749.77, 1056.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7302) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (380, 991, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7067) [M::mem_pestat] mean and std.dev: (1559.05, 1609.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9296) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1171.544 CPU sec, 51.608 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035937, 73, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (268, 339, 424) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 736) [M::mem_pestat] mean and std.dev: (281.23, 101.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 892) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.85) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (353, 2227, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7121) [M::mem_pestat] mean and std.dev: (1648.69, 1167.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9377) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (264, 960, 1873) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5091) [M::mem_pestat] mean and std.dev: (1185.67, 1218.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6700) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.018 CPU sec, 72.912 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035795, 49, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (265, 323, 358) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (79, 544) [M::mem_pestat] mean and std.dev: (293.30, 67.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 637) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (588, 2594, 2663) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6813) [M::mem_pestat] mean and std.dev: (1943.00, 1479.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8888) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (381, 777, 1364) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3330) [M::mem_pestat] mean and std.dev: (933.83, 672.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4313) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1174.564 CPU sec, 54.033 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1036570, 49, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (295, 332, 370) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (145, 520) [M::mem_pestat] mean and std.dev: (324.03, 54.48) [M::mem_pestat] low and high boundaries for proper pairs: (70, 595) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (425, 2583, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6989) [M::mem_pestat] mean and std.dev: (1807.72, 1188.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9177) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (393, 1081, 1333) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3213) [M::mem_pestat] mean and std.dev: (883.92, 511.17) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4153) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1185.234 CPU sec, 62.614 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (57, 1036504, 66, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (273, 328, 390) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (39, 624) [M::mem_pestat] mean and std.dev: (293.74, 79.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 741) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1018, 2593, 3801) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9367) [M::mem_pestat] mean and std.dev: (2949.82, 2571.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13235) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (404, 978, 2463) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6581) [M::mem_pestat] mean and std.dev: (1219.60, 924.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8640) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1175.597 CPU sec, 51.930 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1036586, 65, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (193, 297, 337) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 625) [M::mem_pestat] mean and std.dev: (250.09, 119.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 769) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (357, 2202, 2731) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7479) [M::mem_pestat] mean and std.dev: (1692.80, 1265.37) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9853) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (360, 625, 1676) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4308) [M::mem_pestat] mean and std.dev: (771.71, 604.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5624) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1184.443 CPU sec, 61.891 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036604, 58, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (221, 307, 381) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701) [M::mem_pestat] mean and std.dev: (261.45, 115.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 861) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (405, 2590, 2637) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7101) [M::mem_pestat] mean and std.dev: (1842.91, 1407.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9333) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (433, 1348, 3793) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10513) [M::mem_pestat] mean and std.dev: (2019.50, 1946.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13873) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1173.140 CPU sec, 51.743 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (39, 1036228, 70, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (250, 326, 435) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 805) [M::mem_pestat] mean and std.dev: (278.35, 125.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 990) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (470, 2594, 3460) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9440) [M::mem_pestat] mean and std.dev: (2772.79, 2605.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13193) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (356, 461, 800) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1688) [M::mem_pestat] mean and std.dev: (516.42, 294.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2132) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1226.816 CPU sec, 73.767 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036320, 64, 31) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (228, 333, 415) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 789) [M::mem_pestat] mean and std.dev: (272.26, 111.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 976) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (253, 2215, 2882) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8140) [M::mem_pestat] mean and std.dev: (1869.63, 1632.36) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10769) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (375, 959, 1517) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3801) [M::mem_pestat] mean and std.dev: (937.68, 738.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4943) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1178.120 CPU sec, 54.152 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035577, 74, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (317, 340, 394) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (163, 548) [M::mem_pestat] mean and std.dev: (336.41, 40.08) [M::mem_pestat] low and high boundaries for proper pairs: (86, 625) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (843, 2592, 2851) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6867) [M::mem_pestat] mean and std.dev: (2038.40, 1442.50) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8875) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (473, 1229, 3875) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10679) [M::mem_pestat] mean and std.dev: (2024.28, 2082.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14081) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1186.124 CPU sec, 61.289 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1036095, 64, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 316, 355) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (91, 531) [M::mem_pestat] mean and std.dev: (306.80, 45.10) [M::mem_pestat] low and high boundaries for proper pairs: (3, 619) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (807, 2599, 2949) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7233) [M::mem_pestat] mean and std.dev: (2073.90, 1427.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9375) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (278, 1095, 1579) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4181) [M::mem_pestat] mean and std.dev: (1044.89, 804.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5482) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1175.294 CPU sec, 51.958 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1035855, 53, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (287, 358, 469) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 833) [M::mem_pestat] mean and std.dev: (320.56, 102.67) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1015) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (265, 1994, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7288) [M::mem_pestat] mean and std.dev: (1535.52, 1220.84) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9629) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (389, 885, 1868) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4826) [M::mem_pestat] mean and std.dev: (1125.82, 1070.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6305) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1188.539 CPU sec, 61.475 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036465, 59, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (293, 344, 935) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2219) [M::mem_pestat] mean and std.dev: (513.48, 438.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2861) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (613, 2590, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6625) [M::mem_pestat] mean and std.dev: (1883.55, 1336.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8629) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (349, 1270, 1739) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4519) [M::mem_pestat] mean and std.dev: (1043.31, 786.91) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5909) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1172.204 CPU sec, 51.647 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (58, 1036305, 73, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (231, 325, 355) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 603) [M::mem_pestat] mean and std.dev: (288.26, 99.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 727) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1667, 2590, 3486) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7124) [M::mem_pestat] mean and std.dev: (2015.32, 1375.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8943) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (511, 1098, 1791) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4351) [M::mem_pestat] mean and std.dev: (1106.96, 678.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5631) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1213.923 CPU sec, 72.948 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1036221, 60, 25) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (292, 357, 919) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2173) [M::mem_pestat] mean and std.dev: (429.93, 348.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2800) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (180, 2099, 2849) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8187) [M::mem_pestat] mean and std.dev: (1589.05, 1302.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10856) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (388, 463, 1755) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4489) [M::mem_pestat] mean and std.dev: (842.95, 911.53) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5856) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1180.971 CPU sec, 54.403 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035679, 66, 32) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 327, 374) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (44, 594) [M::mem_pestat] mean and std.dev: (285.31, 82.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 704) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.80) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (283, 2122, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7252) [M::mem_pestat] mean and std.dev: (1678.08, 1297.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9575) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (345, 741, 1311) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3243) [M::mem_pestat] mean and std.dev: (783.87, 596.98) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4209) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1187.235 CPU sec, 63.993 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 1036792, 61, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (261, 346, 1012) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2514) [M::mem_pestat] mean and std.dev: (538.81, 451.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3265) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1172, 2589, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5474) [M::mem_pestat] mean and std.dev: (1904.86, 1110.00) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6908) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (382, 1175, 2829) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7723) [M::mem_pestat] mean and std.dev: (1260.65, 1150.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10170) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1180.250 CPU sec, 52.291 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035621, 63, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (252, 310, 363) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (30, 585) [M::mem_pestat] mean and std.dev: (279.15, 100.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 696) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1048, 2589, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5740) [M::mem_pestat] mean and std.dev: (1880.69, 1110.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7304) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (403, 1095, 2496) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6682) [M::mem_pestat] mean and std.dev: (1517.14, 1322.26) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8775) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1191.018 CPU sec, 62.983 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (33, 1036174, 67, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (281, 310, 368) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (107, 542) [M::mem_pestat] mean and std.dev: (312.00, 65.57) [M::mem_pestat] low and high boundaries for proper pairs: (20, 629) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (395, 2594, 3802) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10616) [M::mem_pestat] mean and std.dev: (2957.99, 2967.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14827) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (289, 386, 3741) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 10645) [M::mem_pestat] mean and std.dev: (2115.79, 2724.02) [M::mem_pestat] low and high boundaries for proper pairs: (1, 14097) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1182.472 CPU sec, 52.254 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1035565, 68, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (300, 350, 824) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1872) [M::mem_pestat] mean and std.dev: (438.78, 373.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2396) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1387, 2598, 3489) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7693) [M::mem_pestat] mean and std.dev: (2215.95, 1649.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9795) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (395, 1017, 1290) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3080) [M::mem_pestat] mean and std.dev: (850.27, 541.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3975) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1194.333 CPU sec, 63.471 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036304, 62, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (256, 307, 358) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (52, 562) [M::mem_pestat] mean and std.dev: (295.19, 77.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 664) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (555, 2589, 2958) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7764) [M::mem_pestat] mean and std.dev: (2099.32, 1591.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10167) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (380, 925, 3009) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8267) [M::mem_pestat] mean and std.dev: (1454.67, 1210.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10896) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 2666668 sequences (240000120 bp)... [M::mem_process_seqs] Processed 2666668 reads in 1209.149 CPU sec, 71.381 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035425, 49, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (301, 332, 487) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 859) [M::mem_pestat] mean and std.dev: (324.18, 149.54) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1045) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (598, 2188, 2705) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6919) [M::mem_pestat] mean and std.dev: (1729.95, 1371.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9026) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (358, 548, 870) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1894) [M::mem_pestat] mean and std.dev: (657.38, 423.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2406) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1178.824 CPU sec, 52.340 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (67, 1035641, 60, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (254, 305, 419) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 749) [M::mem_pestat] mean and std.dev: (289.86, 128.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 914) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1061, 2601, 3241) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7601) [M::mem_pestat] mean and std.dev: (2189.68, 1534.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9781) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (362, 612, 6435) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 18581) [M::mem_pestat] mean and std.dev: (2106.76, 2738.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 24654) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1198.428 CPU sec, 62.850 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1035396, 36, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (269, 328, 356) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (95, 530) [M::mem_pestat] mean and std.dev: (293.21, 59.36) [M::mem_pestat] low and high boundaries for proper pairs: (8, 617) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (232, 2208, 2598) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7330) [M::mem_pestat] mean and std.dev: (1678.47, 1241.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9696) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (366, 854, 1830) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4758) [M::mem_pestat] mean and std.dev: (981.14, 791.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6222) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1180.451 CPU sec, 52.042 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035593, 68, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 318, 985) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2461) [M::mem_pestat] mean and std.dev: (513.73, 538.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3199) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (531, 2590, 2769) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7245) [M::mem_pestat] mean and std.dev: (1976.44, 1430.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9483) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (346, 436, 1084) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2560) [M::mem_pestat] mean and std.dev: (721.53, 658.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3354) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1194.318 CPU sec, 64.689 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (44, 1035345, 43, 30) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (276, 336, 368) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (92, 552) [M::mem_pestat] mean and std.dev: (321.23, 69.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 644) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (399, 2581, 2932) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7998) [M::mem_pestat] mean and std.dev: (1944.54, 1621.19) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10531) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (320, 522, 1677) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4391) [M::mem_pestat] mean and std.dev: (987.79, 944.12) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5748) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1183.168 CPU sec, 52.154 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (60, 1035504, 51, 28) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (198, 305, 362) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690) [M::mem_pestat] mean and std.dev: (248.90, 111.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 854) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (418, 2501, 3136) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8572) [M::mem_pestat] mean and std.dev: (2657.47, 2577.64) [M::mem_pestat] low and high boundaries for proper pairs: (1, 12968) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (348, 441, 1376) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3432) [M::mem_pestat] mean and std.dev: (804.56, 656.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4460) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1239.772 CPU sec, 74.377 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (61, 1036205, 52, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 325, 465) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 901) [M::mem_pestat] mean and std.dev: (287.39, 147.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1119) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1334, 2602, 2623) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5201) [M::mem_pestat] mean and std.dev: (2008.17, 1120.95) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6492) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (357, 889, 1857) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4857) [M::mem_pestat] mean and std.dev: (1129.61, 1013.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6357) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1197.345 CPU sec, 55.094 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035715, 66, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (272, 330, 374) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (68, 578) [M::mem_pestat] mean and std.dev: (301.58, 75.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 680) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (523, 2206, 2608) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6778) [M::mem_pestat] mean and std.dev: (1856.95, 1489.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8863) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (420, 563, 1781) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4503) [M::mem_pestat] mean and std.dev: (1150.73, 1134.92) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5864) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1200.496 CPU sec, 65.309 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035863, 68, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (221, 293, 359) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 635) [M::mem_pestat] mean and std.dev: (248.04, 101.94) [M::mem_pestat] low and high boundaries for proper pairs: (1, 773) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1041, 2121, 2949) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6765) [M::mem_pestat] mean and std.dev: (1815.08, 1245.79) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8673) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (299, 781, 1899) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5099) [M::mem_pestat] mean and std.dev: (1144.06, 991.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6699) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1195.050 CPU sec, 53.179 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (40, 1036289, 70, 17) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (240, 318, 363) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 609) [M::mem_pestat] mean and std.dev: (274.72, 103.32) [M::mem_pestat] low and high boundaries for proper pairs: (1, 732) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (719, 2602, 3287) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8423) [M::mem_pestat] mean and std.dev: (2204.21, 1468.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10991) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (316, 974, 2767) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7669) [M::mem_pestat] mean and std.dev: (1136.88, 1065.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10120) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1195.011 CPU sec, 62.238 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035676, 74, 29) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (290, 334, 925) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2195) [M::mem_pestat] mean and std.dev: (564.65, 508.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2830) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (157, 1469, 2600) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7486) [M::mem_pestat] mean and std.dev: (1587.81, 1542.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9929) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (345, 883, 2028) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5394) [M::mem_pestat] mean and std.dev: (1132.67, 1007.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7077) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1189.066 CPU sec, 52.411 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1035784, 61, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (232, 326, 697) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1627) [M::mem_pestat] mean and std.dev: (361.49, 338.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2092) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (555, 2600, 3481) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9333) [M::mem_pestat] mean and std.dev: (2872.95, 2715.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13736) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (604, 1370, 2233) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5491) [M::mem_pestat] mean and std.dev: (1437.84, 1179.06) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7120) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1215.031 CPU sec, 64.004 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (72, 1035720, 49, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (277, 332, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (73, 583) [M::mem_pestat] mean and std.dev: (300.93, 71.18) [M::mem_pestat] low and high boundaries for proper pairs: (1, 685) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (479, 2521, 2921) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7805) [M::mem_pestat] mean and std.dev: (2048.85, 1552.04) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10247) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (356, 470, 1210) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2918) [M::mem_pestat] mean and std.dev: (814.07, 599.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3772) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::process] read 2666668 sequences (240000120 bp)... [M::mem_process_seqs] Processed 2666668 reads in 1227.674 CPU sec, 75.601 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 1035390, 62, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (289, 342, 393) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (81, 601) [M::mem_pestat] mean and std.dev: (311.08, 71.31) [M::mem_pestat] low and high boundaries for proper pairs: (1, 705) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1226, 2590, 2880) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6188) [M::mem_pestat] mean and std.dev: (2078.19, 1187.99) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7842) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (393, 1124, 2868) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7818) [M::mem_pestat] mean and std.dev: (1606.59, 1721.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10293) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1185.599 CPU sec, 53.079 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1036114, 79, 27) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (244, 309, 860) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2092) [M::mem_pestat] mean and std.dev: (454.82, 424.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2708) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (323, 2583, 2926) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8132) [M::mem_pestat] mean and std.dev: (1972.39, 1621.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10735) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (376, 565, 1138) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2662) [M::mem_pestat] mean and std.dev: (662.08, 420.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3424) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1207.757 CPU sec, 68.035 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 1035575, 55, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (254, 328, 393) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 671) [M::mem_pestat] mean and std.dev: (298.02, 119.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 810) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (476, 1446, 2602) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6854) [M::mem_pestat] mean and std.dev: (1573.98, 1327.21) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8980) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (345, 1255, 1732) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4506) [M::mem_pestat] mean and std.dev: (1196.33, 1037.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5893) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1190.019 CPU sec, 52.490 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1036006, 54, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (269, 310, 359) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (89, 539) [M::mem_pestat] mean and std.dev: (292.02, 59.29) [M::mem_pestat] low and high boundaries for proper pairs: (1, 629) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (402, 1998, 2611) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7029) [M::mem_pestat] mean and std.dev: (1825.24, 1301.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9238) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (354, 442, 1497) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3783) [M::mem_pestat] mean and std.dev: (640.78, 480.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4926) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.715 CPU sec, 66.328 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1034828, 47, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (252, 305, 367) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (22, 597) [M::mem_pestat] mean and std.dev: (267.57, 96.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 712) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (214, 2160, 2643) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7501) [M::mem_pestat] mean and std.dev: (1929.47, 1754.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9930) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (417, 453, 980) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2106) [M::mem_pestat] mean and std.dev: (641.26, 453.55) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2669) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1198.776 CPU sec, 52.816 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (63, 1035719, 61, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (282, 337, 475) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 861) [M::mem_pestat] mean and std.dev: (321.02, 139.58) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1054) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.35, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1025, 2596, 2945) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6785) [M::mem_pestat] mean and std.dev: (2005.93, 1247.10) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8705) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (359, 786, 1618) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4136) [M::mem_pestat] mean and std.dev: (911.33, 725.88) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5395) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1252.124 CPU sec, 74.631 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (43, 1035835, 54, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (251, 300, 401) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 701) [M::mem_pestat] mean and std.dev: (267.47, 138.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 851) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (401, 2035, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7016) [M::mem_pestat] mean and std.dev: (1590.08, 1139.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9221) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (268, 433, 1119) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2821) [M::mem_pestat] mean and std.dev: (627.47, 480.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3672) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1200.450 CPU sec, 55.519 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (62, 1035492, 71, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (283, 329, 390) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (69, 604) [M::mem_pestat] mean and std.dev: (307.21, 75.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 711) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (481, 2150, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6865) [M::mem_pestat] mean and std.dev: (1790.97, 1386.45) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8993) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (391, 1073, 1837) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4729) [M::mem_pestat] mean and std.dev: (1287.33, 1123.60) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6175) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1199.433 CPU sec, 64.667 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (47, 1036334, 66, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (287, 338, 405) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (51, 641) [M::mem_pestat] mean and std.dev: (317.25, 89.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 759) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (73, 1979, 3018) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8908) [M::mem_pestat] mean and std.dev: (2548.88, 2792.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13718) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (388, 904, 1608) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4048) [M::mem_pestat] mean and std.dev: (966.00, 647.13) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5268) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1206.869 CPU sec, 53.277 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (50, 1036051, 65, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (252, 324, 883) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2145) [M::mem_pestat] mean and std.dev: (461.46, 422.05) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2776) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (219, 1913, 2601) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7365) [M::mem_pestat] mean and std.dev: (1595.97, 1301.46) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9747) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (422, 1186, 1233) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2855) [M::mem_pestat] mean and std.dev: (895.75, 602.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3666) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1196.531 CPU sec, 62.416 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1036033, 63, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (257, 330, 374) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (23, 608) [M::mem_pestat] mean and std.dev: (259.05, 119.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 735) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (616, 2579, 2891) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7441) [M::mem_pestat] mean and std.dev: (2090.43, 1757.48) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9716) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (291, 764, 1378) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3552) [M::mem_pestat] mean and std.dev: (785.43, 564.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4639) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1190.910 CPU sec, 52.462 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1034801, 57, 33) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (296, 329, 404) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (80, 620) [M::mem_pestat] mean and std.dev: (312.95, 87.43) [M::mem_pestat] low and high boundaries for proper pairs: (1, 728) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (592, 2597, 3451) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9169) [M::mem_pestat] mean and std.dev: (2810.35, 2576.75) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13117) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (424, 759, 1685) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4207) [M::mem_pestat] mean and std.dev: (954.50, 819.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 5468) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1206.704 CPU sec, 62.516 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (65, 1036073, 67, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (276, 315, 491) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 921) [M::mem_pestat] mean and std.dev: (295.15, 108.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 1136) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1145, 2594, 2635) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5615) [M::mem_pestat] mean and std.dev: (2053.44, 1279.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7173) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (386, 1080, 1450) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3578) [M::mem_pestat] mean and std.dev: (957.15, 783.41) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4642) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1224.867 CPU sec, 76.038 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (56, 1035764, 63, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (271, 315, 369) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (75, 565) [M::mem_pestat] mean and std.dev: (297.91, 69.27) [M::mem_pestat] low and high boundaries for proper pairs: (1, 663) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (428, 2504, 2613) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6983) [M::mem_pestat] mean and std.dev: (1746.74, 1269.15) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9168) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (347, 1016, 1778) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4640) [M::mem_pestat] mean and std.dev: (1045.32, 909.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6071) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1193.972 CPU sec, 53.363 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1035943, 40, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (284, 345, 443) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 761) [M::mem_pestat] mean and std.dev: (316.54, 133.83) [M::mem_pestat] low and high boundaries for proper pairs: (1, 920) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1131, 2599, 3950) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9588) [M::mem_pestat] mean and std.dev: (2946.10, 2670.03) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13626) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (357, 448, 1185) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2841) [M::mem_pestat] mean and std.dev: (673.52, 545.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3669) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1201.024 CPU sec, 63.082 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (42, 1036080, 58, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (258, 315, 373) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (28, 603) [M::mem_pestat] mean and std.dev: (290.36, 94.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 718) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1209, 2606, 3614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8424) [M::mem_pestat] mean and std.dev: (2337.32, 1487.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10829) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (408, 1147, 2097) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5475) [M::mem_pestat] mean and std.dev: (1450.87, 1255.65) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7164) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1199.573 CPU sec, 52.934 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1036462, 69, 24) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (253, 335, 379) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 631) [M::mem_pestat] mean and std.dev: (281.24, 116.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 757) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (283, 2374, 2674) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7456) [M::mem_pestat] mean and std.dev: (1839.84, 1489.86) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9847) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (342, 784, 1416) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3564) [M::mem_pestat] mean and std.dev: (894.04, 666.69) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4638) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1201.471 CPU sec, 64.107 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (59, 1035262, 56, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (222, 326, 378) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 690) [M::mem_pestat] mean and std.dev: (260.86, 107.24) [M::mem_pestat] low and high boundaries for proper pairs: (1, 846) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (222, 2420, 2612) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7392) [M::mem_pestat] mean and std.dev: (1757.11, 1476.96) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9782) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (349, 967, 1968) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5206) [M::mem_pestat] mean and std.dev: (1460.37, 1332.22) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6825) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1208.580 CPU sec, 53.326 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (45, 1035435, 61, 15) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (278, 346, 416) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (2, 692) [M::mem_pestat] mean and std.dev: (319.82, 128.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 832) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (210, 1753, 2620) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7440) [M::mem_pestat] mean and std.dev: (1694.38, 1532.74) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9850) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (365, 754, 1126) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2648) [M::mem_pestat] mean and std.dev: (758.53, 540.82) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3409) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1264.514 CPU sec, 74.935 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (46, 1036310, 57, 29) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (263, 336, 398) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 668) [M::mem_pestat] mean and std.dev: (295.07, 106.35) [M::mem_pestat] low and high boundaries for proper pairs: (1, 803) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (291, 2588, 2957) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8289) [M::mem_pestat] mean and std.dev: (2132.33, 1906.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10955) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (420, 836, 2425) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6435) [M::mem_pestat] mean and std.dev: (1374.52, 1260.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8440) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1206.580 CPU sec, 55.388 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035919, 73, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (281, 332, 434) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 740) [M::mem_pestat] mean and std.dev: (285.35, 103.08) [M::mem_pestat] low and high boundaries for proper pairs: (1, 893) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (217, 1792, 2614) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7408) [M::mem_pestat] mean and std.dev: (1539.65, 1318.39) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9805) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (384, 1003, 1437) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3543) [M::mem_pestat] mean and std.dev: (1007.50, 793.76) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4596) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1193.028 CPU sec, 57.410 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1035799, 69, 19) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (264, 328, 384) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (24, 624) [M::mem_pestat] mean and std.dev: (265.85, 104.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 744) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.40, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1213, 2590, 2631) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5467) [M::mem_pestat] mean and std.dev: (1955.34, 1202.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6885) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (401, 1354, 3098) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8492) [M::mem_pestat] mean and std.dev: (1814.42, 1585.77) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11189) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1185.887 CPU sec, 52.215 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (64, 1035975, 60, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (247, 302, 353) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (35, 565) [M::mem_pestat] mean and std.dev: (269.75, 113.52) [M::mem_pestat] low and high boundaries for proper pairs: (1, 724) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1219, 2585, 2649) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5509) [M::mem_pestat] mean and std.dev: (1940.83, 1345.56) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7323) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (374, 1269, 2036) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5360) [M::mem_pestat] mean and std.dev: (1273.16, 994.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7022) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1202.808 CPU sec, 63.781 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (55, 1035851, 64, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (291, 346, 781) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 1761) [M::mem_pestat] mean and std.dev: (496.96, 400.25) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2251) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (281, 2577, 2959) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8315) [M::mem_pestat] mean and std.dev: (1881.57, 1638.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10993) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (370, 1181, 2278) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6094) [M::mem_pestat] mean and std.dev: (1456.10, 1433.68) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8002) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1189.538 CPU sec, 52.551 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (54, 1035857, 61, 21) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (267, 344, 416) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 714) [M::mem_pestat] mean and std.dev: (302.14, 107.59) [M::mem_pestat] low and high boundaries for proper pairs: (1, 863) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.39, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (435, 2042, 2759) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7407) [M::mem_pestat] mean and std.dev: (1739.16, 1179.66) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9731) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (444, 907, 2062) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 5298) [M::mem_pestat] mean and std.dev: (1153.89, 1082.81) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6916) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1202.549 CPU sec, 61.304 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::process] read 2666668 sequences (240000120 bp)... [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (69, 1036300, 68, 20) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (243, 330, 409) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 741) [M::mem_pestat] mean and std.dev: (282.09, 100.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 907) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.36, 12.83) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (608, 2588, 3624) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9656) [M::mem_pestat] mean and std.dev: (2825.76, 2606.73) [M::mem_pestat] low and high boundaries for proper pairs: (1, 13253) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (458, 1127, 2429) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6371) [M::mem_pestat] mean and std.dev: (1490.75, 1324.01) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8342) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1227.475 CPU sec, 76.011 real sec [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (49, 1035992, 65, 16) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (249, 303, 370) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (7, 612) [M::mem_pestat] mean and std.dev: (258.68, 96.33) [M::mem_pestat] low and high boundaries for proper pairs: (1, 733) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (358, 2250, 2996) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 8272) [M::mem_pestat] mean and std.dev: (1901.71, 1695.93) [M::mem_pestat] low and high boundaries for proper pairs: (1, 10910) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (373, 714, 3258) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 9028) [M::mem_pestat] mean and std.dev: (1173.62, 1267.72) [M::mem_pestat] low and high boundaries for proper pairs: (1, 11913) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1195.511 CPU sec, 53.303 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (53, 1036269, 55, 18) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (301, 349, 888) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2062) [M::mem_pestat] mean and std.dev: (515.44, 393.51) [M::mem_pestat] low and high boundaries for proper pairs: (1, 2649) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (661, 2284, 2609) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6505) [M::mem_pestat] mean and std.dev: (1721.20, 1258.97) [M::mem_pestat] low and high boundaries for proper pairs: (1, 8453) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (334, 483, 1426) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 3610) [M::mem_pestat] mean and std.dev: (817.56, 614.11) [M::mem_pestat] low and high boundaries for proper pairs: (1, 4702) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1184.229 CPU sec, 53.235 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (48, 1035498, 55, 23) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (258, 333, 417) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 735) [M::mem_pestat] mean and std.dev: (296.57, 131.30) [M::mem_pestat] low and high boundaries for proper pairs: (1, 894) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.38, 12.82) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (237, 2351, 2617) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7377) [M::mem_pestat] mean and std.dev: (1690.14, 1512.78) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9757) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (331, 464, 1147) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2779) [M::mem_pestat] mean and std.dev: (674.95, 538.85) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3595) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1189.772 CPU sec, 52.331 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (51, 1036289, 71, 22) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (271, 324, 421) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 721) [M::mem_pestat] mean and std.dev: (300.12, 117.47) [M::mem_pestat] low and high boundaries for proper pairs: (1, 871) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (278, 1898, 2606) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7262) [M::mem_pestat] mean and std.dev: (1616.60, 1212.61) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9590) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (365, 896, 1130) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 2660) [M::mem_pestat] mean and std.dev: (768.71, 474.80) [M::mem_pestat] low and high boundaries for proper pairs: (1, 3425) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1194.393 CPU sec, 64.087 real sec [M::process] read 2666668 sequences (240000120 bp)... [M::process] 0 single-end sequences; 2666668 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (52, 1035872, 64, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (239, 345, 426) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 800) [M::mem_pestat] mean and std.dev: (280.19, 134.89) [M::mem_pestat] low and high boundaries for proper pairs: (1, 987) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.81) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (222, 2592, 2629) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7443) [M::mem_pestat] mean and std.dev: (1895.10, 1359.57) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9850) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (398, 1217, 1857) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 4775) [M::mem_pestat] mean and std.dev: (1088.38, 829.07) [M::mem_pestat] low and high boundaries for proper pairs: (1, 6234) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2666668 reads in 1196.733 CPU sec, 52.761 real sec [M::process] read 2275416 sequences (204787440 bp)... [M::process] 0 single-end sequences; 2275416 paired-end sequences [M::mem_pestat] # candidate unique pairs for (FF, FR, RF, RR): (34, 883510, 51, 14) [M::mem_pestat] analyzing insert size distribution for orientation FF... [M::mem_pestat] (25, 50, 75) percentile: (289, 319, 382) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (103, 568) [M::mem_pestat] mean and std.dev: (312.68, 47.57) [M::mem_pestat] low and high boundaries for proper pairs: (10, 661) [M::mem_pestat] analyzing insert size distribution for orientation FR... [M::mem_pestat] (25, 50, 75) percentile: (455, 464, 473) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (419, 509) [M::mem_pestat] mean and std.dev: (464.37, 12.84) [M::mem_pestat] low and high boundaries for proper pairs: (401, 527) [M::mem_pestat] analyzing insert size distribution for orientation RF... [M::mem_pestat] (25, 50, 75) percentile: (1447, 2591, 2980) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 6046) [M::mem_pestat] mean and std.dev: (1937.45, 1125.90) [M::mem_pestat] low and high boundaries for proper pairs: (1, 7579) [M::mem_pestat] analyzing insert size distribution for orientation RR... [M::mem_pestat] (25, 50, 75) percentile: (560, 1534, 2890) [M::mem_pestat] low and high boundaries for computing mean and std.dev: (1, 7550) [M::mem_pestat] mean and std.dev: (2006.71, 1671.23) [M::mem_pestat] low and high boundaries for proper pairs: (1, 9880) [M::mem_pestat] skip orientation FF [M::mem_pestat] skip orientation RF [M::mem_pestat] skip orientation RR [M::mem_process_seqs] Processed 2275416 reads in 1004.957 CPU sec, 43.480 real sec [main] Version: 0.7.17-r1188 [main] CMD: /home/csyk2proj/tools/bwa.kit/bwa mem -p -t24 -R@RG\tID:KPGP-00227\tPL:ILLUMINA\tSM:KPGP-00227 -C /home/csyk2proj/data/bwa.kit/hs38DH.fa - [main] Real time: 52873.688 sec; CPU: 586165.691 sec