| identifier |
PRJDB15572 |
| type |
bioproject |
| sameAs |
|
| organism |
Mus musculus
|
| title |
A novel way to reduce ASO toxicity |
| description |
mPCS1 is a fully PS-modified 14-mer LNA gapmer antisense oligonucleotide (ASO) with two phosphodiester-linked GalNAc units. mPCS1 targets mouse Pcsk9 (Proprotein To assess the molecular impact of BS on ASO toxicity, RNA sequencing (RNA-Seq) analysis was performed. Specifically, C57BL/6J mice were subcutaneously treated with 100 nmol/kg of mPCS1 or BRO and liver global gene expression was assessed 72 h after administration Day 3 was selected for RNA-seq analysis. |
| data type |
Transcriptome or Gene Expression
|
| publication |
|
| properties ▽ |
{...}
|
| dbXrefs |
|
| distribution |
JSONJSON-LD
|
| Download |
|
| status |
public |
| visibility |
unrestricted-access |
| dateCreated |
2023-03-27T16:32:58+09:00 |
| dateModified |
2023-11-09T13:01:23+09:00 |
| datePublished |
2023-11-09T13:01:23+09:00 |