description |
The global epidemic of multidrug resistant Salmonella Typhimurium DT104 provides an important example, both in terms of the agent and its resistance, of a type-specific epidemic occurring within an endemic infection pattern. Here, with a unique collection of isolates collected contemporaneously from humans and animals in Scotland, benchmarked against a sample of international-derived isolates, we have used whole genome sequencing to dissect the phylogenetic histories of the bacterium and its antimicrobial resistance genes through the entire course of the epidemic. |