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identifier PRJDB2049
type bioproject
sra-study  DRP000631
organism Aspergillus oryzae 3.042
title Genome Sequencing and Comparative Genomes and Transcriptomes Analysis of Aspergillus oryzae 3.042 and A100-8
description Aspergillus oryzae has a very long history of use in the production of traditional fermented foods and beverages. Comparison of the genomes of the A. oryzae 3.042 and A. oryzae A100-8 which diverged by the N+ ion implantation mutagenesis reveals considerable similarities. However, some differences between gene-sequences were observed such as: SNPs, nucleotide deletion or insertion; some of these may reflect the ability of A. oryzae to secrete proteases and explain the mechanism of mycelium growth. Both A. oryzae 3.042 and A. oryzae A100-8 have a strikingly larger proportion of genes encoding proteases, 50% of these are extracellular enzymes. Transcriptional analysis of the two strains during three different growth processes provided further insights into the genes and pathways involved in secreting proteases and cell growth. This has led to the development of the different levels of functional genomic analysis—the transcriptome, proteome, and metabolism, as well as high-throughput approaches for determining phenotypes.
data type Other
external link
sra-run  DRR002367
sra-submission  DRA000600
biosample  SAMD00006241
sra-study  DRP000631
sra-sample  DRS001665
sra-experiment  DRX001776
distribution JSONJSON-LD
status public
visibility unrestricted-access
dateCreated 2014-05-12T00:46:27+0000
dateModified 2014-12-18T05:11:41+0000
datePublished 2014-12-18T05:11:41+0000