| identifier |
PRJDB2979 |
| type |
bioproject |
| sameAs |
|
| organism |
Hepatitis C virus subtype 1b
|
| title |
HCV NS5A sequencing |
| description |
Recent advances in interferon-free treatment could lead to the eradication of HCV from patients infected with HCV. One of the direct-acting anti-viral agents, HCV NS5A inhibitor is available for these combination therapies. However, naturally occurring resistance-associated variants (RAVs) to HCV NS5A inhibitors in treatment-naïve patients with chronic hepatitis C are still unknown. Here, we performed ultra-deep sequencing and analyzed previously reported RAVs in a total 132 HCV genotype 1b-infected Japanese patients who had never used HCV NS5A inhibitors. We also performed direct-sequencing by Sanger method and examined the differences between the results of the two methods. |
| data type |
Targeted Locus (Loci)
|
| publication |
|
| properties ▽ |
{...}
|
| dbXrefs |
|
| distribution |
JSONJSON-LD
|
| Download |
|
| status |
public |
| visibility |
unrestricted-access |
| dateCreated |
2014-07-16T02:45:04+09:00 |
| dateModified |
2014-09-30T00:11:28+09:00 |
| datePublished |
2014-09-30T00:11:28+09:00 |