home > bioproject > PRJDB3993
identifier PRJDB3993
type bioproject
sameAs
organism Streptococcus pneumoniae
title Capsule switching and antimicrobial resistance acquired during a repeated Streptococcus pneumoniae pneumonia episodes
description Seven repeated pneumonia episodes caused by a Streptococcus pneumoniae strain were analyzed in a pediatric patient with cerebral palsy. A total of 10 S. pneumoniae strains were obtained and serotype 6B was isolated from the first 5 episodes whereas 6A was isolated from the last 2. Whole genome sequencing showed clonality of the 10 isolates with 10 SNVs in the genomes. Among these SNVs, one single point mutation in the wciP gene was presumed to relate to the serotype switching from 6B to 6A, and the others in parC and gyrA were related to fluoroquinolone resistance.
data type Genome Sequencing
publication
properties 
{...}
dbXrefs
sra-run  DRR037130DRR037131DRR037132DRR037133DRR037134DRR037135DRR037136DRR037137DRR037138
sra-submission  DRA003687
biosample  SAMD00032020SAMD00032021SAMD00032022SAMD00032023SAMD00032024SAMD00032025SAMD00032026SAMD00032027SAMD00032028
sra-study  DRP002713
sra-sample  DRS020514DRS020515DRS020516DRS020517DRS020518DRS020519DRS020520DRS020521DRS020522
sra-experiment  DRX033365DRX033366DRX033367DRX033368DRX033369DRX033370DRX033371DRX033372DRX033373
distribution JSONJSON-LD
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status public
visibility unrestricted-access
dateCreated 2015-06-15T05:59:45+09:00
dateModified 2015-08-04T13:01:17+09:00
datePublished 2015-08-04T13:01:17+09:00