| identifier |
PRJDB4053 |
| type |
bioproject |
| sameAs |
|
| organism |
Bombyx mori
|
| title |
Identification of the enzyme that trims the 3'-end of piRNAs in silkworms |
| description |
Piwi-interacting RNAs (piRNAs) are predominantly expressed in germline cells and function in transposon silencing. Unlike other small RNAs, piRNAs are processed from long single-stranded RNAs independently of Dicer. At the final step in piRNA biogenesis, 3' ends of precursor piRNAs (pre-piRNAs) that are longer than the mature length are trimmed by the exonuclease Trimmer in cooperation with its partner protein Papi, and subsequently 2'-O-methylated by Hen1, resulting in mature piRNAs. We performed piRNA profiling in silkworm BmN4 cells in which Trimmer and/or Papi have been depleted. |
| data type |
small RNA sequencing
|
| publication |
|
| properties ▽ |
{...}
|
| dbXrefs |
|
| distribution |
JSONJSON-LD
|
| Download |
|
| status |
public |
| visibility |
unrestricted-access |
| dateCreated |
2015-07-06T10:38:15+09:00 |
| dateModified |
2016-02-25T13:06:19+09:00 |
| datePublished |
2016-02-25T13:06:17+09:00 |