| identifier |
PRJDB4861 |
| type |
bioproject |
| sameAs |
|
| organism |
Mus musculus
|
| title |
Role of p53 in HSV-1 encephalitisis |
| description |
p53 is a multifunctional host cellular protein in the cellular response to a broad range of stress because of its ability to regulate various cellular pathways. Recently, we reported that p53 plays an important role in the replication of herpes simplex virus type 1 (HSV-1) in a cultured cell line (Maruzuru et al., J. Virol., 2013). However, the involvement of p53 in viral pathogenesis remains unclear. To investigate the effect of p53 knock-out on global viral and host cellular gene expression in the brains of infected mice, we performed whole-transcriptome shotgun sequencing analysis of the brains from infected p53+/+ and p53-/- mice following intracranial infection. |
| data type |
Transcriptome or Gene Expression
|
| publication |
|
| properties ▽ |
{...}
|
| dbXrefs |
|
| distribution |
JSONJSON-LD
|
| Download |
|
| status |
public |
| visibility |
unrestricted-access |
| dateCreated |
2016-05-20T11:33:45+09:00 |
| dateModified |
2016-05-23T13:23:12+09:00 |
| datePublished |
2016-05-23T13:23:11+09:00 |