home > bioproject > PRJDB5226
identifier PRJDB5226
type bioproject
sameAs
organism Danio rerio
title Effects of local gut tumor on whole-organismal gene expressions in zebrafish
description How tumors affects whole-organismal physiology remains largely unknown. To address this, we established the novel gut tumor model in zebrafish, Danio rerio. This model develops tumor at an early stage of juvenile development, when zebrafish larvae are small (<4mm), enabling us to perform whole-organismal RNA-seq experiments. Control or tumor-bearing zebrafish were dissected into the three parts under microscope: the liver, the gut/gut tumor, and others. Tissues from >10 individuals were pooled and RNA-extracted. Analyses on these RNA-seq samples identified a set of host genes affected by the gut tumor, contributing to discovering novel tumor-organ interactions and their mediators in zebrafish.
data type Transcriptome or Gene Expression
publication
properties 
{...}
dbXrefs
sra-run  DRR075397DRR075398DRR075399DRR075400DRR075401DRR075402
sra-submission  DRA005199
biosample  SAMD00065411SAMD00065412SAMD00065413SAMD00065414SAMD00065415SAMD00065416
sra-study  DRP004473
sra-sample  DRS075492DRS075493DRS075494DRS075495DRS075496DRS075497
sra-experiment  DRX069311DRX069312DRX069313DRX069314DRX069315DRX069316
distribution JSONJSON-LD
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status public
visibility unrestricted-access
dateCreated 2016-10-19T01:17:20+09:00
dateModified 2018-09-19T13:04:09+09:00
datePublished 2018-09-19T13:04:07+09:00