| identifier |
PRJDB5524 |
| type |
bioproject |
| sameAs |
|
| organism |
Mus musculus
|
| title |
Transcriptome-wide identification of ADAR1 p150-specific RNA editing sites in macrophage cell line |
| description |
ADARs are RNA editing enzymes that catalyze the deamination of adenosine to inosine in double-stranded RNAs. In mammals, there are two isoforms of ADAR1 including a p110 isoform, which is constitutively and ubiquitously expressed, and a p150 isoform regulated by an IFN-inducible promoter. The mutation in ADAR1 gene causes Aicardi-Goutieres syndrome (AGS), a severe autoimmune disease in human. Furthermore, the significant decrease in RNA-editing activity was found in the p150 isoform mutant associated with AGS. In this study, we will perform transcriptome-wide analysis and identify the targets of ADAR1p150 isoform. |
| data type |
Transcriptome or Gene Expression
|
| publication |
|
| properties ▽ |
{...}
|
| dbXrefs |
|
| distribution |
JSONJSON-LD
|
| Download |
|
| status |
public |
| visibility |
unrestricted-access |
| dateCreated |
2017-02-07T05:55:06+09:00 |
| dateModified |
2019-02-07T13:05:33+09:00 |
| datePublished |
2019-02-07T13:05:33+09:00 |