identifier |
PRJDB5831 |
type |
bioproject |
sameAs |
|
organism |
Cricetulus griseus
|
title |
CHO-DG44 |
description |
Chinese hamster ovary (CHO) cells have chromosome number distribution. Previously, DG44-SC20 and DG44-SC39 cell lines with modal chromosome numbers 20 and 39 were isolated from parental CHO-DG44 cells, and IgG3 expressing cells named IgG3-SC20 and IgG3-SC39 were established, respectively. Even though all of the IgG3-SC20 clones and half of the IgG3-SC39 clones contained the same number of vector integration sites (one each), antibody productivities of IgG3-SC39 clones were higher than those in any of the IgG3-SC20 clones. In this study, we performed transcriptome analysis to investigate the characteristic of high producer cells with chromosome aneuploidy. |
data type |
Transcriptome or Gene Expression
|
publication |
|
properties ▽ |
{...}
|
dbXrefs |
|
distribution |
JSONJSON-LD
|
Download |
|
status |
public |
visibility |
unrestricted-access |
dateCreated |
2017-06-02T06:15:07+09:00 |
dateModified |
2019-06-02T13:02:02+09:00 |
datePublished |
2019-06-02T13:02:02+09:00 |