home > bioproject > PRJDB6276
identifier PRJDB6276
type bioproject
sameAs
organism Escherichia coli
title IncN plasmid carried blaIMP-6 in concealed-type carbapenem-susceptible Escherichia coli
description The carbapenem-susceptible carbapenemase-producing Enterobacteriaceae is a current issue, because it carries carbapenemase genes but undetectable by antibiotics susceptibility patterns only. In 2010, imipenem and meropenem-susceptible but blaIMP-6-positive Escherichia coli A56-1S strain was isolated from urine specimen in Japan, and the Carba NP test was negative. Meropenem-resistant E. coli A56-1R strain was selected from the susceptible A56-1S by 1 µg/mL meropenem. Whole genome sequencing was performed using MiSeq and PacBio RSII sequencer, and comparative genome analysis of these strains revealed that the IS26 insertion into transcriptional factor gene was found in A56-1R, while the transcriptional factor gene is intact in A56-1S.
data type Genome Sequencing
publication
properties 
{...}
dbXrefs
sra-run  DRR101600DRR101601
sra-submission  DRA006165
biosample  SAMD00093076SAMD00093077
sra-study  DRP004471
sra-sample  DRS075466DRS075467
sra-experiment  DRX095020DRX095021
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status public
visibility unrestricted-access
dateCreated 2017-08-24T06:28:18+09:00
dateModified 2018-09-19T13:04:22+09:00
datePublished 2018-09-19T13:04:22+09:00