| identifier |
PRJDB6510 |
| type |
bioproject |
| sameAs |
|
| organism |
Mus musculus
|
| title |
Analysis of functional roles of Regnase-1 in airway epithelial cells controlling mucosal immunity |
| description |
Regnase-1 is an RNase critical for the regulation of immune cell activation. In addition to hematopoietic cells, we found that Regnase-1 is expressed in the airway epithelial cells. Mice lacking Regnase-1 specifically in airway epithelial cells showed the enhanced induction of immune reaction in response to Pseudomonas aeruginosa infection. Thus, we performed transcriptome analysis using wild-type and Regnase-1-deficient MTECs (mouse tracheal epithelial cells) to analyze the underlying mechanism of Regnase-1 mediated regulation of airway epithelial cell activation. |
| data type |
Transcriptome or Gene Expression
|
| publication |
|
| properties ▽ |
{...}
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| dbXrefs |
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| distribution |
JSONJSON-LD
|
| Download |
|
| status |
public |
| visibility |
unrestricted-access |
| dateCreated |
2017-11-16T04:22:08+09:00 |
| dateModified |
2019-11-16T13:15:33+09:00 |
| datePublished |
2019-11-16T13:15:33+09:00 |