home > bioproject > PRJDB7205
identifier PRJDB7205
type bioproject
sameAs
organism Homo sapiens
title Investigation of energy metabolism regulators in adipocytes and cancer cells
description Cancer cells acquire certain important characteristics, including a unique metabolic phenotype, upon transformation and metastasis. Some of these characteristics are also associated with the regulation of preadipocyte function, as well as the differentiation of adipocytes, pointing to commonalities between the mechanisms of pathogenesis associated with oncogenesis and adipogenesis. To investigate the commonalities in p53-dependent metabolic regulation between adipocytes and cancer cells, we performed RNA-seq analysis with two distinct systems: 1) H1299 cells infected with adenoviruses expressing either p53 or LacZ and 2) preadipocytes treated with doxorubicin to induce DNA damage or untreated.
data type Transcriptome or Gene Expression
publication
30061407
properties 
{...}
dbXrefs
sra-run  DRR142741DRR142742DRR142743DRR142744DRR142745DRR142746DRR142747DRR142748
sra-submission  DRA007067
biosample  SAMD00131347SAMD00131348SAMD00131349SAMD00131350SAMD00131351SAMD00131352SAMD00131353SAMD00131354
sra-study  DRP004333
sra-sample  DRS071384DRS071385DRS071386DRS071387DRS071388DRS071389DRS071390DRS071391
sra-experiment  DRX135455DRX135456DRX135457DRX135458DRX135459DRX135460DRX135461DRX135462
distribution JSONJSON-LD
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status public
visibility unrestricted-access
dateCreated 2018-07-11T07:11:53+09:00
dateModified 2018-08-29T06:19:57+09:00
datePublished 2018-07-18T13:01:31+09:00