home > bioproject > PRJDB7935
identifier PRJDB7935
type bioproject
sameAs
organism human bile metagenome
title The Metagenomic analysis of bile samples from xanthogranulomatous cholecystitis patients
description Xanthogranulomatous cholecystitis (XGC) is characterized histologically by the accumulation of numerous foamy macrophages in the gallbladder, resulting in thickening of the gallbladder wall. Moreover, XGC is frequently diagnosed as gallbladder carcinoma. Escherichia coli antigens have been detected immunohistologically in XGC lesions, and E. coli was reported to be involved in the pathogenesis of XGC, with scavenger receptor class A and CXCL16-CXCR interactions. These resulted suggested that E. coli infections of the gallbladder play an important role in the onset and/or early stages of XGC. However, it is unclear whether other pathogens are associated with the cause and progression of XGC. In this study, we analyzed the microbiota in bile samples from XGC patients to reveal the cause and progression of XGC.
data type Metagenome
publication
properties 
{...}
dbXrefs
sra-run  DRR165747DRR165748
sra-submission  DRA007947
biosample  SAMD00159167SAMD00159168
sra-study  DRP004868
sra-sample  DRS088931DRS088932
sra-experiment  DRX156363DRX156364
distribution JSONJSON-LD
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status public
visibility unrestricted-access
dateCreated 2019-01-22T08:13:40+09:00
dateModified 2019-01-23T07:15:52+09:00
datePublished 2019-01-23T07:15:52+09:00