| identifier |
PRJDB8540 |
| type |
bioproject |
| sameAs |
|
| organism |
Simian rotavirus A strain RRV
|
| title |
Bottleneck Size-Dependent Changes in the Genetic Diversity of Rotavirus |
| description |
RNA viruses form a dynamic distribution of mutant swarm due to the accumulation in the viral genome. The genetic diversity of a viral population is affected by several factors, including a bottleneck. Human-to-human transmission exemplifies a bottleneck effect in that only part of a viral population can reach the next susceptible hosts. In the present study, the rhesus rotavirus (RRV) strain of Rotavirus A was serially passaged five times under at a multiplicity of infection (MOI) of 0.001 in duplicate. Using next generation sequencing, we obtained SNPs information of RRV populations, and then estimated a nucleotide diversity, synonymous/non-synonymous substitution rate and evolutionary rate. |
| data type |
Genome Sequencing
|
| publication |
|
| properties ▽ |
{...}
|
| dbXrefs |
|
| distribution |
JSONJSON-LD
|
| Download |
|
| status |
public |
| visibility |
unrestricted-access |
| dateCreated |
2019-07-09T01:35:22+09:00 |
| dateModified |
2019-07-12T13:05:58+09:00 |
| datePublished |
2019-07-12T13:05:58+09:00 |