home > bioproject > PRJDB8564
identifier PRJDB8564
type bioproject
sameAs
organism Eremothecium gossypii
title Genomic analysis of a riboflavin-overproducing Eremothecium gossypii (Ashbya gossypii) mutant isolated by disparity mutagenesis
description Eremothecium gossypii (Ashbya gossypii) naturally overproduces riboflavin and has been utilized for industrial riboflavin production. Regarding, a riboflavin-overproducing mutant isolated by disparity mutagenesis, its genomic analysis was carried out. In the genomic analysis, 33 homozygous and 1377 heterozygous mutations were detected. Among these heterozygous mutations, the proportion of mutated reads in each gene was different, ranging from 21 to 75%. This study provides new insights into riboflavin production in this fungus and the usefulness of disparity mutagenesis for the creation of new types of mutants for metabolic engineering.
data type Genome Sequencing Variation
publication
17650208
21573938
25128926
properties 
{...}
dbXrefs
sra-run  DRR185903DRR185904
sra-submission  DRA008709
biosample  SAMD00180042SAMD00180043
sra-study  DRP005291
sra-sample  DRS104100DRS104101
sra-experiment  DRX176381DRX176382
distribution JSONJSON-LD
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status public
visibility unrestricted-access
dateCreated 2019-07-15T10:06:04+09:00
dateModified 2019-07-19T13:00:20+09:00
datePublished 2019-07-19T13:00:20+09:00