| identifier | PRJDB9617 | ||
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| type | bioproject | ||
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| organism | Mus musculus | ||
| title | Transcriptome analysis in HBZ-transgenic/IL-6 knockout mice | ||
| description | A viral gene, HTLV-1 bZIP factor (HBZ), triggers systemic inflammation and T-cell lymphoma in transgenic mice. Here we show that loss of IL-6 accelerated inflammation and lymphomagenesis in HBZ transgenic mice. To understand the molecular mechanisms for the acceleration of inflammation and oncogenesis in HBZ-Tg/IL-6 KO mice, we performed RNA-seq analysis using splenic CD4+ T cells from 4 strains: WT, HBZ-Tg, IL-6 KO, and HBZ-Tg/IL-6 KO. | ||
| data type | Transcriptome or Gene Expression | ||
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| distribution | JSONJSON-LD | ||
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| status | public | ||
| visibility | unrestricted-access | ||
| dateCreated | 2020-03-31T01:11:09+09:00 | ||
| dateModified | 2020-05-23T13:24:14+09:00 | ||
| datePublished | 2020-05-23T13:24:14+09:00 |