home > bioproject > PRJEB10914
identifier PRJEB10914
type bioproject
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title Developmental Ecology of the Human Microbiome - Restoration Study of babies.
description Humans are the only mammals that interrupt exposure of newborns to maternal vaginal microbiota with cesarean birthing, increasingly practiced in many countries. Babies delivered by C-section acquire a microbiota that differs significantly from that of vaginally delivered infants, and C-section delivery has been associated with increased risk for immune and metabolic disorders. Here we present a pilot study that partially restores the natural primary microbiota of infants delivered by C-section by exposing them to maternal vaginal fluids at birth. Similar to vaginally delivered babies, the gut, oral, and skin microbiome of these newborns during the first month of life was enriched in vaginal bacteria absent in unexposed C-section infants. Our results demonstrate that many vaginal microbes can be restored at birth in C-section delivered babies.
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dbXrefs
sra-run  ERR1020613ERR1020614ERR1020615ERR1020616ERR1020617ERR1020618ERR1020619ERR1020620ERR1020621ERR1020622 More
sra-submission  ERA486171
biosample  SAMEA3544177SAMEA3544178SAMEA3544179SAMEA3544180SAMEA3544181SAMEA3544182SAMEA3544183SAMEA3544184SAMEA3544185SAMEA3544186 More
sra-study  ERP012216
sra-sample  ERS851326ERS851327ERS851328ERS851329ERS851330ERS851331ERS851332ERS851333ERS851334ERS851335 More
sra-experiment  ERX1099553ERX1099554ERX1099555ERX1099556ERX1099557ERX1099558ERX1099559ERX1099560ERX1099561ERX1099562 More
distribution JSONJSON-LD
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status public
visibility unrestricted-access
dateCreated 2016-01-05T00:00:00Z
dateModified 2016-01-05T00:00:00Z
datePublished 2015-09-21T00:00:00Z