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identifier PRJEB14365
type bioproject
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title Origins of MLL cancer stem cells govern leukemic self-renewal mediated by B-catenin and Hoxa9
description From mice, strand-specific DNA-Seq and RNA-Seq of granulocyte-myeloid progenitors (GMP) and hematopoietic stem cells (HSC). Cancer stem cells (CSC) were created with MLL-ENL transfections using puromycin for both GMP and HSCs. Further knock-outs were created of -catenin (Ctnnb1) and Hoxa9.
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