home > bioproject > PRJEB2536
identifier PRJEB2536
type bioproject
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title RNAi of signal transduction components in HCT116 cells
description We performed RNAi knockdown experiments on 7 different signal transduction components of the Wnt pathway in HCT116 colon cancer cells and prepared RNA libraries from the poly-adenylated fraction of the RNA. SOLiD sequencing of strand-specific, barcoded transcriptome libraries yielded expression profiles allowing us to extract common pathway signatures and enabeling us to perform susequent nested effects modelling. the resulting pathway models yields new insight in the pathway topology in colon cancer.
data type Transcriptome or Gene expression
organization
publication
properties 
{...}
dbXrefs
sra-run  ERR034229ERR034230ERR034231ERR034232ERR034233ERR034234ERR034235ERR034236ERR034237ERR034238 More
sra-submission  ERA030760
biosample  SAMEA1316892SAMEA1316881SAMEA1316882SAMEA1316884SAMEA1316890SAMEA1316894SAMEA1316888SAMEA1316886SAMEA1316885SAMEA1316889 More
sra-study  ERP000671
sra-sample  ERS033061ERS033062ERS033063ERS033064ERS033065ERS033066ERS033067ERS033068ERS033069ERS033070 More
sra-experiment  ERX012725ERX012726
distribution JSONJSON-LD
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status public
visibility unrestricted-access
dateCreated 2014-04-21T00:00:00Z
dateModified 2014-04-21T00:00:00Z
datePublished 2014-04-18T00:00:00Z