home > bioproject > PRJEB2673
identifier PRJEB2673
type bioproject
title Mouse_Transposon_Validation
description An in vivo tumorigenesis system that samples tissue and developmental contexts in the whole animal by using DNA transposons to deliver and stochastically express pools of candidate cancer gene cDNAs. Each transposon carries a promoter-less cDNA that traps promoters and enhancers as it translocates in the genome. If a transposon traps a promoter that expresses an oncogenic cDNA at an appropriate level, in a susceptible tissue, at a suitable developmental stage, so as to give a transformation phenotype with selective clonal advantage – tumorigenesis occurs. Exome sequencing uncovers cooperating mutations to the expressed cDNAs, and also insertional profiles of the tumour clones. This data is part of a pre-publication release. For information on the proper use of pre-publication data shared by the Wellcome Trust Sanger Institute (including details of any publication moratoria), please see http://www.sanger.ac.uk/datasharing/
data type Other
sra-run  ERR069940ERR069941ERR069942ERR069943ERR069944ERR069945ERR069946ERR069947ERR084967ERR084968 More
sra-submission  ERA081635ERA087397ERA121034ERA123492ERA129566
biosample  SAMEA1094156SAMEA1094155SAMEA1094161SAMEA1094157SAMEA1094162SAMEA1094153SAMEA1094154SAMEA1094160SAMEA1094158SAMEA1094152 More
sra-study  ERP000896
sra-sample  ERS053085ERS053086ERS053082ERS053083ERS053084ERS053080ERS053081ERS053079ERS076872ERS076873 More
sra-experiment  ERX047793ERX047794ERX047795ERX047796ERX047797ERX047798ERX047799ERX047800ERX062733ERX062734 More
distribution JSONJSON-LD
bioproject.xml  HTTPS FTP
status public
visibility unrestricted-access
dateCreated 2012-01-19T00:00:00Z
dateModified 2012-01-19T00:00:00Z
datePublished 2012-01-19T00:00:00Z