home > bioproject > PRJEB2930
identifier PRJEB2930
type bioproject
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title NuRD-mediated gene repression in mouse embryonic stem cells
description To obtain a global view of NuRD-mediated transcriptional regulation, gene expression profiles of wild-type and Mbd3-null ES cells were compared by microarray analysis. In the absence of Mbd3, which encodes a core structural component of NuRD, the complex does not form and embryonic development stalls at the implantation stage.
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publication
NuRD-mediated deacetylation of H3K27 facilitates recruitment of Polycomb Repressive Complex 2 to direct gene repression.
properties 
{...}
dbXrefs
sra-run  ERR103025ERR103026ERR103027ERR103028ERR103029ERR103030ERR103031ERR103032ERR103033ERR103034 More
sra-submission  ERA097665
biosample  SAMEA1095980SAMEA1095979SAMEA1095981SAMEA1095978
sra-study  ERP001288
sra-sample  ERS104129ERS104127ERS104126ERS104128
sra-experiment  ERX080476ERX080471ERX080467ERX080474ERX080466ERX080463ERX080462ERX080465ERX080475ERX080461 More
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status public
visibility unrestricted-access
dateCreated 2012-03-13T00:00:00Z
dateModified 2012-03-13T00:00:00Z
datePublished 2012-03-13T00:00:00Z