identifier | PRJEB4772 | ||||||||||||
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type | bioproject | ||||||||||||
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title | Transcriptional landscape, long non-coding RNAs and post-transcriptional regulation in hematopoietic stem/progenitor cell differentiation | ||||||||||||
description | Hematopoietic stem cells (HSC) possess life-long self-renewal activity and generate a series of multipotent progenitors that differentiate into lineage-committed progenitors and subsequently mature cells. Recently, functionally distinct stem and progenitor cell types have been identified, however, a systems-wide understanding of the underlying gene regulation is lacking. Here, we present the global transcriptome of ex vivo isolated mouse multipotent hematopoietic stem/progenitor cells (HSPCs, LinnegSca-1+c-Kit+) and myeloid committed precursors (LinnegSca-1-c-Kit+) as revealed by next-generation sequencing (RNA-seq). | ||||||||||||
data type | Transcriptome or Gene expression | ||||||||||||
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distribution | JSONJSON-LD | ||||||||||||
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status | public | ||||||||||||
visibility | unrestricted-access | ||||||||||||
dateCreated | 2014-10-09T00:00:00Z | ||||||||||||
dateModified | 2014-10-09T00:00:00Z | ||||||||||||
datePublished | 2014-10-08T00:00:00Z |