| identifier | PRJNA210778 | ||
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| type | bioproject | ||
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| organism | Homo sapiens | ||
| title | RNA-seq of Tumor Initiating Cells (TICs) from Lung Squamous Cell Carcinoma (LSCC) lines reveals PRKCI dependent Hedgehog (HH) Signalling | ||
| description | RNA-seq analysis was performed on TICs and the parental counterparts of 4 LSCC cell lines. In addition, PRKCI knock down (KD) variants of these cells were sequenced. Subsequent analysis revealed that activation of HH signaling, a known driver of the TIC phenotype, is dependent on PRKCI expression.Overall design: Examination of TICS, parental cells, parental PRKCI KD cells, and TIC PRKCI KD cells | ||
| data type | Transcriptome or Gene expression | ||
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