home > bioproject > PRJNA271271
identifier PRJNA271271
type bioproject
sameAs
GEO  GSE64538
organism Macaca fascicularis
title Next generation sequencing reveals a controlled immune response to Zaire Ebola virus challenge in cynomolgus macaques immunized with VSVΔG/ZEBOVgp
description RNA deep sequencing analysis was perfromed on PBMCs obtained from cynomolgus macaques (CMs) prior to and after immunization with VSV carrying ZEBOVgp (VSVΔG/ZEBOVgp) and at multiple points after ZEBOV challengeOverall design: We selected two groups of animals either (3 animals in each group) immunized with VSVDG/ZEBOVgp or VSVΔG/MARVgp. A baseline blood draw was taken at day -28, with post immunization and challenge blood draws at days 0, 4, 7, 14 and 35. Analysis for this study was done on PBMC isolated from whole blood of each animal.
data type Transcriptome or Gene expression
organization
publication
25589554
external link